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A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
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Busulfan FDA Label
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Carboplatin FDA Label
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Cyclophosphamide FDA Label
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Dacarbazine FDA Label
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Doxorubicin FDA Label
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Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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Erlotinib FDA Label
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Etoposide FDA Label
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Everolimus FDA Label
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Fludarabine FDA Label
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Ifosfamide FDA Label
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Irinotecan FDA Label
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Isotretinoin FDA Label
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Melphalan FDA Label
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Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2020
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Sirolimus FDA Label
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Temozolomide FDA Label
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Thiotepa FDA Label
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Topotecan FDA Label
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Tretinoin FDA Label
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Vidarabine FDA Label
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Vincristine FDA Label
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ClinicalTrials.gov (NCT03275402) 131I-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/Leptomeningeal Metastases. U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT00810238) C-Cure Clinical Trial. U.S. National Institutes of Health.
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Overview and recent advances in the treatment of neuroblastoma. Expert Rev Anticancer Ther. 2017 Apr;17(4):369-386.
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ClinicalTrials.gov (NCT03275402) 131I-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/Leptomeningeal Metastases. U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT02765243) Anti-GD2 4th Generation CART Cells Targeting Refractory and/or Recurrent Neuroblastoma
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Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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Clinical pipeline report, company report or official report of Apeiron Biologics.
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Clinical pipeline report, company report or official report of Y-mAbs Therapeutics.
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004852)
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ClinicalTrials.gov (NCT04438304) Positron Emission Tomography Imaging of Participants With Known or Suspected Neuroendocrine Tumours Using 64Cu SARTATE: A Multi-Centre, Single Arm, Non-Randomised, Blinded-Review, Phase II Study. U.S.National Institutes of Health.
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ClinicalTrials.gov (NCT04023331) 67Cu-SARTATE Peptide Receptor Radionuclide Therapy Administered to Pediatric Patients With High-Risk Neuroblastoma. U.S. National Institutes of Health.
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Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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ClinicalTrials.gov (NCT03373097) Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma
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ClinicalTrials.gov (NCT02761915) A Cancer Research UK Trial of Anti-GD2 T-cells (1RG-CART)
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ClinicalTrials.gov (NCT02107963) A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors
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ClinicalTrials.gov (NCT03635632) C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma (GAIL-N)
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ClinicalTrials.gov (NCT02311621) Engineered Neuroblastoma Cellular Immunotherapy (ENCIT)-01
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ClinicalTrials.gov (NCT01953900) iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and Neuroblastoma
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ClinicalTrials.gov (NCT01822652) 3rd Generation GD-2 Chimeric Antigen Receptor and iCaspase Suicide Safety Switch, Neuroblastoma, GRAIN
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ClinicalTrials.gov (NCT03721068) Phase I Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma
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Clinical pipeline report, company report or official report of Kuur Therapeutics.
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ClinicalTrials.gov (NCT02337309) SF1126 for Patients With Relapsed or Refractory Neuroblastoma. U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT02919046) Study Evaluating the Efficacy and Safety With CAR-T for Relapsed or Refractory Neuroblastoma in Children
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Valproic Acid FDA Label
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Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan invivo.Eur J Cancer. 2017 Sep;83:132-141. doi: 10.1016/j.ejca.2017.06.024. Epub 2017 Jul 20.
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Carnosic acid suppresses the production of amyloid- 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.Neurosci Res. 2013 Feb;75(2):94-102. doi: 10.1016/j.neures.2012.11.007. Epub 2012 Dec 17.
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Agonist regulation of adenylate cyclase activity in neuroblastoma x glioma hybrid NG108-15 cells transfected to co-express adenylate cyclase type II and the beta 2-adrenoceptor. Evidence that adenylate cyclase is the limiting component for receptor-mediated stimulation of adenylate cyclase activity.Biochem J. 1996 Sep 15;318 ( Pt 3)(Pt 3):1033-9. doi: 10.1042/bj3181033.
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N-cadherin in neuroblastoma disease: expression and clinical significance.PLoS One. 2012;7(2):e31206. doi: 10.1371/journal.pone.0031206. Epub 2012 Feb 15.
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Early and late effects of pharmacological ALK inhibition on the neuroblastoma transcriptome.Oncotarget. 2017 Nov 6;8(63):106820-106832. doi: 10.18632/oncotarget.22423. eCollection 2017 Dec 5.
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Genetic variant rs3750625 in the 3'UTR of ADRA2A affects stress-dependent acute pain severity after trauma and alters a microRNA-34a regulatory site.Pain. 2017 Feb;158(2):230-239. doi: 10.1097/j.pain.0000000000000742.
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Macrophage-Derived IL1 and TNF Regulate Arginine Metabolism in Neuroblastoma.Cancer Res. 2019 Feb 1;79(3):611-624. doi: 10.1158/0008-5472.CAN-18-2139. Epub 2018 Dec 13.
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Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma.Oncotarget. 2019 Sep 24;10(54):5645-5659. doi: 10.18632/oncotarget.27210. eCollection 2019 Sep 24.
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Prognostic Impact of Activated Leucocyte Cell Adhesion Molecule (ALCAM/CD166) in Infantile Neuroblastoma.Anticancer Res. 2016 Aug;36(8):3991-5.
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Expression of DHA-Metabolizing Enzyme Alox15 is Regulated by Selective Histone Acetylation in Neuroblastoma Cells. Neurochem Res. 2018 Mar;43(3):540-555.
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Differential role of RIP1 in Smac mimetic-mediated chemosensitization of neuroblastoma cells.Oncotarget. 2015 Dec 8;6(39):41522-34. doi: 10.18632/oncotarget.6308.
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The secretion of the angiogenic and neurotrophic factor angiogenin is COPII and microtubule dependent.Exp Cell Res. 2019 Aug 15;381(2):265-279. doi: 10.1016/j.yexcr.2019.05.025. Epub 2019 May 22.
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TRIM59 knockdown inhibits cell proliferation by down-regulating the Wnt/-catenin signaling pathway in neuroblastoma.Biosci Rep. 2019 Jan 18;39(1):BSR20181277. doi: 10.1042/BSR20181277. Print 2019 Jan 31.
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Neuron-Specific Apolipoprotein E4 (1-272) Fragment Induces Tau Hyperphosphorylation and Axonopathy via Triggering Endoplasmic Reticulum Stress.J Alzheimers Dis. 2019;71(2):597-611. doi: 10.3233/JAD-190419.
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ASIC1 promotes differentiation of neuroblastoma by negatively regulating Notch signaling pathway.Oncotarget. 2017 Jan 31;8(5):8283-8293. doi: 10.18632/oncotarget.14164.
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Adenovirus with hexon Tat-protein transduction domain modification exhibits increased therapeutic effect in experimental neuroblastoma and neuroendocrine tumors.J Virol. 2011 Dec;85(24):13114-23. doi: 10.1128/JVI.05759-11. Epub 2011 Sep 28.
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MiR-20a-5p suppresses tumor proliferation by targeting autophagy-related gene 7 in neuroblastoma.Cancer Cell Int. 2018 Jan 4;18:5. doi: 10.1186/s12935-017-0499-2. eCollection 2018.
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The p16 and p18 tumor suppressor genes in neuroblastoma: implications for drug resistance.Cancer Lett. 1996 Jul 12;104(2):183-92. doi: 10.1016/0304-3835(96)04250-4.
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ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT.Oncogene. 2016 Jul 14;35(28):3681-91. doi: 10.1038/onc.2015.434. Epub 2015 Nov 30.
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Palmitate-Induced SREBP1 Expression and Activation Underlies the Increased BACE 1 Activity and Amyloid Beta Genesis.Mol Neurobiol. 2019 Jul;56(7):5256-5269. doi: 10.1007/s12035-018-1451-8. Epub 2018 Dec 19.
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Therapeutic potential of BAK gene silencing in aluminum induced neural cell degeneration.J Inorg Biochem. 2009 Nov;103(11):1514-20. doi: 10.1016/j.jinorgbio.2009.06.010. Epub 2009 Aug 14.
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The involvement of tau in nucleolar transcription and the stress response.Acta Neuropathol Commun. 2018 Jul 31;6(1):70. doi: 10.1186/s40478-018-0565-6.
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miR-146a induces apoptosis in neuroblastoma cells by targeting BCL11A.Med Hypotheses. 2018 Aug;117:21-27. doi: 10.1016/j.mehy.2018.05.019. Epub 2018 May 26.
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Biglycan, a Nitric Oxide-Downregulated Proteoglycan, Prevents Nitric Oxide-Induced Neuronal Cell Apoptosis via Targeting Erk1/2 and p38 Signaling Pathways.J Mol Neurosci. 2018 Sep;66(1):68-76. doi: 10.1007/s12031-018-1151-x. Epub 2018 Aug 7.
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Identification of a potential tumor differentiation factor receptor candidate in prostate cancer cells.FEBS J. 2012 Jul;279(14):2579-94. doi: 10.1111/j.1742-4658.2012.08641.x. Epub 2012 Jun 14.
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Downregulation of bone morphogenetic protein receptor 2 promotes the development of neuroblastoma.Biochem Biophys Res Commun. 2017 Jan 29;483(1):609-616. doi: 10.1016/j.bbrc.2016.12.095. Epub 2016 Dec 18.
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Dual BRD4 and AURKA Inhibition Is Synergistic against MYCN-Amplified and Nonamplified Neuroblastoma.Neoplasia. 2018 Oct;20(10):965-974. doi: 10.1016/j.neo.2018.08.002. Epub 2018 Aug 25.
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Prognostic relevance of genetic alterations in the p32 region of chromosome 1 in neuroblastoma.Eur J Cancer. 1997 Oct;33(12):1983-5. doi: 10.1016/s0959-8049(97)00239-6.
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C9orf72 Proteins Regulate Autophagy and Undergo Autophagosomal or Proteasomal Degradation in a Cell Type-Dependent Manner.Cells. 2019 Oct 10;8(10):1233. doi: 10.3390/cells8101233.
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Modulation of human -synuclein aggregation by a combined effect of calcium and dopamine.Neurobiol Dis. 2014 Mar;63:115-28. doi: 10.1016/j.nbd.2013.11.004. Epub 2013 Nov 20.
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Regulatory characterisation of the schizophrenia-associated CACNA1C proximal promoter and the potential role for the transcription factor EZH2 in schizophrenia aetiology.Schizophr Res. 2018 Sep;199:168-175. doi: 10.1016/j.schres.2018.02.036. Epub 2018 Feb 28.
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Differential effects of PKA-controlled CaMKK2 variants on neuronal differentiation.RNA Biol. 2011 Nov-Dec;8(6):1061-72. doi: 10.4161/rna.8.6.16691. Epub 2011 Nov 1.
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Efficiency of CAR-T Therapy for Treatment of Solid Tumor in Clinical Trials: A Meta-Analysis.Dis Markers. 2019 Feb 11;2019:3425291. doi: 10.1155/2019/3425291. eCollection 2019.
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Cyclin E1 is a common target of BMI1 and MYCN and a prognostic marker for neuroblastoma progression.Oncogene. 2012 Aug 16;31(33):3785-95. doi: 10.1038/onc.2011.536. Epub 2011 Nov 28.
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Methylation of tumor-suppressor genes in neuroblastoma: The RASSF1A gene is almost always methylated in primary tumors.Pediatr Blood Cancer. 2008 Jan;50(1):29-32. doi: 10.1002/pbc.21279.
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Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma.Oncotarget. 2017 Jul 22;8(36):60368-60377. doi: 10.18632/oncotarget.19499. eCollection 2017 Sep 1.
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Future of Theranostics: An Outlook on Precision Oncology in Nuclear Medicine.J Nucl Med. 2019 Sep;60(Suppl 2):13S-19S. doi: 10.2967/jnumed.118.220566.
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TFH cells promote B cell maturation and antibody production in neuroblastoma.BMC Immunol. 2017 Jul 7;18(1):36. doi: 10.1186/s12865-017-0216-x.
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NDRG1 promotes the multidrug resistance of neuroblastoma cells with upregulated expression of drug resistant proteins.Biomed Pharmacother. 2015 Dec;76:46-51. doi: 10.1016/j.biopha.2015.10.015. Epub 2015 Nov 10.
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CDC20siRNA and paclitaxel co-loaded nanometric liposomes of a nipecotic acid-derived cationic amphiphile inhibit xenografted neuroblastoma.Nanoscale. 2017 Jan 19;9(3):1201-1212. doi: 10.1039/c6nr07532k.
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JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma.Nat Commun. 2019 Jul 25;10(1):3319. doi: 10.1038/s41467-019-11132-w.
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Phenotype, cancer risk, and surveillance in Beckwith-Wiedemann syndrome depending on molecular genetic subgroups.Am J Med Genet A. 2016 Sep;170(9):2248-60. doi: 10.1002/ajmg.a.37801. Epub 2016 Jul 15.
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Structural and functional analysis of cyclin-dependent kinase inhibitor genes (CDKN2A, CDKN2B, and CDKN2C) in neuroblastoma.Pediatr Res. 1998 Jan;43(1):139-44. doi: 10.1203/00006450-199801000-00021.
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Mitogen-activated protein kinase (MEK/ERK) inhibition sensitizes cancer cells to centromere-associated protein E inhibition.Int J Cancer. 2013 Feb 1;132(3):E149-57. doi: 10.1002/ijc.27781. Epub 2012 Sep 28.
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Arctic A40 blocks the nicotine-induced neuroprotective effect of CHRNA7 by inhibiting the ERK1/2 pathway in human neuroblastoma cells.Neurochem Int. 2017 Nov;110:49-56. doi: 10.1016/j.neuint.2017.09.005. Epub 2017 Sep 8.
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Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracellular calcium levels by selected L-type calcium channel blockers.Biochim Biophys Acta. 2011 Feb;1810(2):186-91. doi: 10.1016/j.bbagen.2010.09.004. Epub 2010 Oct 7.
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Inhibition of chemerin/CMKLR1 axis in neuroblastoma cells reduces clonogenicity and cell viability in vitro and impairs tumor growth in vivo.Oncotarget. 2017 Jul 27;8(56):95135-95151. doi: 10.18632/oncotarget.19619. eCollection 2017 Nov 10.
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L-3-n-butylphthalide reduces tau phosphorylation and improves cognitive deficits in APP/PS1-Alzheimer's transgenic mice.J Alzheimers Dis. 2012;29(2):379-91. doi: 10.3233/JAD-2011-111577.
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Nuclear cereblon modulates transcriptional activity of Ikaros and regulates its downstream target, enkephalin, in human neuroblastoma cells.Biochem Biophys Res Commun. 2016 Aug 26;477(3):388-94. doi: 10.1016/j.bbrc.2016.06.091. Epub 2016 Jun 18.
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The activation of type 1 corticotropin releasing factor receptor (CRF-R1) inhibits proliferation and promotes differentiation of neuroblastoma cells in vitro via p27(Kip1) protein up-regulation and c-Myc mRNA down-regulation.Mol Cell Endocrinol. 2015 Sep 5;412:205-15. doi: 10.1016/j.mce.2015.05.004. Epub 2015 May 7.
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Cytokine receptor-like factor 1 (CRLF1) protects against 6-hydroxydopamine toxicity independent of the gp130/JAK signaling pathway.PLoS One. 2013 Jun 20;8(6):e66548. doi: 10.1371/journal.pone.0066548. Print 2013.
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Facilitation of 9,10-phenanthrenequinone-elicited neuroblastoma cell apoptosis by NAD(P)H:quinone oxidoreductase 1. Chem Biol Interact. 2018 Jan 5;279:10-20.
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Low aerobic mitochondrial energy metabolism in poorly- or undifferentiated neuroblastoma.BMC Cancer. 2010 Apr 19;10:149. doi: 10.1186/1471-2407-10-149.
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G-CSF receptor positive neuroblastoma subpopulations are enriched in chemotherapy-resistant or relapsed tumors and are highly tumorigenic.Cancer Res. 2013 Jul 1;73(13):4134-46. doi: 10.1158/0008-5472.CAN-12-4056. Epub 2013 May 16.
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Functional genomics identifies therapeutic targets for MYC-driven cancer.Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9545-50. doi: 10.1073/pnas.1121119109. Epub 2012 May 23.
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Down-regulation of BORIS/CTCFL efficiently regulates cancer stemness and metastasis in MYCN amplified neuroblastoma cell line by modulating Wnt/-catenin signaling pathway.Biochem Biophys Res Commun. 2017 Feb 26;484(1):93-99. doi: 10.1016/j.bbrc.2017.01.066. Epub 2017 Jan 17.
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Down-regulation of natural resistance-associated macrophage protein-1 (Nramp1) is associated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)/1-methyl-4-phenylpyridinium (MPP(+) )-induced -synuclein accumulation and neurotoxicity.Neuropathol Appl Neurobiol. 2019 Feb;45(2):157-173. doi: 10.1111/nan.12493. Epub 2018 May 15.
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Association of CYP3A4/5 genotypes and expression with the survival of patients with neuroblastoma.Mol Med Rep. 2015 Feb;11(2):1462-8. doi: 10.3892/mmr.2014.2835. Epub 2014 Oct 31.
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Differential expression of delta-like gene and protein in neuroblastoma, ganglioneuroblastoma and ganglioneuroma.Mod Pathol. 2005 May;18(5):656-62. doi: 10.1038/modpathol.3800335.
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DFF45/ICAD restores cisplatin-induced nuclear fragmentation but not DNA cleavage in DFF45-deficient neuroblastoma cells.Oncogene. 2007 Aug 16;26(38):5669-73. doi: 10.1038/sj.onc.1210352. Epub 2007 Mar 12.
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MiR-192 directly binds and regulates Dicer1 expression in neuroblastoma.PLoS One. 2013 Nov 1;8(11):e78713. doi: 10.1371/journal.pone.0078713. eCollection 2013.
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LncRNA XIST facilitates cell growth, migration and invasion via modulating H3 histone methylation of DKK1 in neuroblastoma.Cell Cycle. 2019 Aug;18(16):1882-1892. doi: 10.1080/15384101.2019.1632134. Epub 2019 Jul 7.
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ERK1/2-mediated disruption of BDNF-TrkB signaling causes synaptic impairment contributing to fluoride-induced developmental neurotoxicity.Toxicology. 2018 Dec 1;410:222-230. doi: 10.1016/j.tox.2018.08.009. Epub 2018 Aug 18.
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The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription.Cancer Res. 2017 May 1;77(9):2522-2533. doi: 10.1158/0008-5472.CAN-16-1663. Epub 2017 Feb 16.
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DUSP5 expression associates with poor prognosis in human neuroblastoma.Exp Mol Pathol. 2018 Dec;105(3):272-278. doi: 10.1016/j.yexmp.2018.08.008. Epub 2018 Aug 30.
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Valproic acid suppresses Warburg effect and tumor progression in neuroblastoma.Biochem Biophys Res Commun. 2019 Jan 1;508(1):9-16. doi: 10.1016/j.bbrc.2018.11.103. Epub 2018 Nov 20.
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Endothelin-converting enzymes degrade -synuclein and are reduced in dementia with Lewy bodies.J Neurochem. 2017 Apr;141(2):275-286. doi: 10.1111/jnc.13974. Epub 2017 Mar 29.
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Lead Neurotoxicity on Human Neuroblastoma Cell Line SH-SY5Y is Mediated via Transcription Factor EGR1/Zif268 Induced Disrupted in Scherophernia-1 Activation.Neurochem Res. 2018 Jul;43(7):1308-1316. doi: 10.1007/s11064-018-2539-2. Epub 2018 Jun 4.
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Histone-lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, cell invasion, and DNA methylation of human neuroblastoma cells.Anticancer Drugs. 2013 Jun;24(5):484-93. doi: 10.1097/CAD.0b013e32835ffdbb.
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Aluminum Activates PERK-EIF2 Signaling and Inflammatory Proteins in Human Neuroblastoma SH-SY5Y Cells.Biol Trace Elem Res. 2016 Jul;172(1):108-119. doi: 10.1007/s12011-015-0553-7. Epub 2015 Nov 7.
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MEK inhibitor trametinib does not prevent the growth of anaplastic lymphoma kinase (ALK)-addicted neuroblastomas.Sci Signal. 2017 Nov 28;10(507):eaam7550. doi: 10.1126/scisignal.aam7550.
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Destabilization of MYC/MYCN by the mitochondrial inhibitors, metaiodobenzylguanidine, metformin and phenformin.Int J Mol Med. 2014 Jan;33(1):35-42. doi: 10.3892/ijmm.2013.1545. Epub 2013 Nov 1.
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Sumoylation of EphB1 Suppresses Neuroblastoma Tumorigenesis via Inhibiting PKC Activation.Cell Physiol Biochem. 2018;45(6):2283-2292. doi: 10.1159/000488174. Epub 2018 Mar 13.
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NF-kappaB, and not MYCN, regulates MHC class I and endoplasmic reticulum aminopeptidases in human neuroblastoma cells.Cancer Res. 2010 Feb 1;70(3):916-24. doi: 10.1158/0008-5472.CAN-09-2582. Epub 2010 Jan 26.
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Ampulla of Vater Carcinoma: Sequencing Analysis Identifies TP53 Status as a Novel Independent Prognostic Factor and Potentially Actionable ERBB, PI3K, and WNT Pathways Gene Mutations.Ann Surg. 2018 Jan;267(1):149-156. doi: 10.1097/SLA.0000000000001999.
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Differential regulation of HIF-1 and HIF-2 in neuroblastoma: Estrogen-related receptor alpha (ERR) regulates HIF2A transcription and correlates to poor outcome.Biochem Biophys Res Commun. 2015 Jun 5;461(3):560-7. doi: 10.1016/j.bbrc.2015.04.083. Epub 2015 Apr 23.
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Estrogen receptor enhances the transcriptional activity of ETS-1 and promotes the proliferation, migration and invasion of neuroblastoma cell in a ligand dependent manner.BMC Cancer. 2015 Jun 30;15:491. doi: 10.1186/s12885-015-1495-3.
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TAT-mediated transduction of bacterial redox proteins generates a cytoprotective effect on neuronal cells.PLoS One. 2017 Sep 8;12(9):e0184617. doi: 10.1371/journal.pone.0184617. eCollection 2017.
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GPR40 activation leads to CREB and ERK phosphorylation in primary cultures of neurons from the mouse CNS and in human neuroblastoma cells.Hippocampus. 2014 Jul;24(7):733-9. doi: 10.1002/hipo.22263. Epub 2014 Feb 27.
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Protective Effects of Fibroblast Growth Factor 21 Against Amyloid-Beta(1-42)-Induced Toxicity in SH-SY5Y Cells.Neurotox Res. 2018 Oct;34(3):574-583. doi: 10.1007/s12640-018-9914-2. Epub 2018 Jun 5.
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HDAC inhibitors suppress c-Jun/Fra-1-mediated proliferation through transcriptionally downregulating MKK7 and Raf1 in neuroblastoma cells.Oncotarget. 2016 Feb 9;7(6):6727-47. doi: 10.18632/oncotarget.6797.
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The role of formyl peptide receptor 1 (FPR1) in neuroblastoma tumorigenesis.BMC Cancer. 2016 Jul 18;16:490. doi: 10.1186/s12885-016-2545-1.
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MicroRNA-141 and its associated gene FUS modulate proliferation, migration and cisplatin chemosensitivity in neuroblastoma cell lines.Oncol Rep. 2016 May;35(5):2943-51. doi: 10.3892/or.2016.4640. Epub 2016 Feb 26.
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Inhibition of glycogen synthase kinase-3 by falcarindiol isolated from Japanese Parsley (Oenanthe javanica).J Agric Food Chem. 2013 Aug 7;61(31):7515-21. doi: 10.1021/jf401042m. Epub 2013 Jul 29.
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Genetic and epigenetic regulation on the transcription of GABRB2: Genotype-dependent hydroxymethylation and methylation alterations in schizophrenia.J Psychiatr Res. 2017 May;88:9-17. doi: 10.1016/j.jpsychires.2016.12.019. Epub 2016 Dec 28.
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Peptides derived from the knuckle epitope of BMP-9 induce the cholinergic differentiation and inactivate GSk3beta in human SH-SY5Y neuroblastoma cells.Sci Rep. 2017 Jul 5;7(1):4695. doi: 10.1038/s41598-017-04835-x.
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MES23.5 DA Immortalized Neuroblastoma Cells Self-protect Against Early Injury by Overexpressing Glial Cell-derived Neurotrophic Factor via Akt1/Eya1/Six2 Signaling.J Mol Neurosci. 2020 Mar;70(3):328-339. doi: 10.1007/s12031-019-01416-7. Epub 2019 Nov 13.
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