Details of the Drug Reposition

General Information of This Drug (ID: DMTBKF3)

Drug Name
Piperacillin   DMTBKF3
Synonyms
PIPC; Peperacillin; Peracin; Pipercillin; Pipracil; Pipril; PIPERACILLIN SODIUM; Piperacillin Monosodium Salt; Piperacillin anhydrous; Cl-227193; Peracin (TN); Piperacillin (INN); Piperacillin (anhydrous); Pipracil, Piper; T-1220; Zobactin (TN); (2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S-(2alpha,5alpha,6beta(S*)))-6-(((((4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl)amino)phenylacetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid; 4-ethyl-2,3-dioxopiperazine carbonyl ampicillin; 6-(D-(-)-alpha-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)phenylacetamido)penicillanicacid; 6beta-{(2R)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylic acid
Therapeutic Class
Antibiotics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
8 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Staphylococcus aureus infection DISK6PTH N.A. Approved [1]
Pseudomonas aeruginosa infectious disease DISC07AQ N.A. Approved [1]
Peritonitis DISMCMLQ N.A. Approved [1]
Acute gonococcal cervicitis DIS4LKDT N.A. Approved [1]
Bacterial infection DIS5QJ9S 1A00-1C4Z Approved [2]
Bacteremia DIS6N9RZ 1A73 Approved [1]
Appendicitis DIS4GOLF DB10 Approved [1]
Urinary tract infection DISMT6UV GC08 Approved [1]
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⏷ Show the Full List of 8 Indications(s)
2 Withdrawn Indication(s)
Indication Name Indication ID ICD-11 Status REF
Acute gonococcal endometritis DISZ8BW7 N.A. Withdrawn [3]
Peritonsillar abscess DISZZXTZ N.A. Withdrawn [4]
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1 Discontinued in Phase 3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Escherichia coli infection DISPP65M 1A03 Discontinued in Phase 3 [5]
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3 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Rhinoscleroma DISNSWVK N.A. Discontinued in Phase 2 [6]
Gonorrhea DISQ5AO6 1A7Z Discontinued in Phase 2 [7]
Bacterial pneumonia DISPW7PH CA40.0 Discontinued in Phase 2 [8]
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1 Investigative Indication(s)
Indication Name Indication ID ICD-11 Status REF
Pelvic inflammatory disease DISWQR4J GA05 Investigative [1]
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References

1 Piperacillin FDA Label
2 Zosyn (piperacillin/tazobactam) reformulation: Expanded compatibility and coadministration with lactated Ringer's solutions and selected aminoglycosides. Ther Clin Risk Manag. 2008 Apr;4(2):303-14.
3 Effect of Acid Suppression With Esomeprazole on Vocal Cord Granulomas
4 Valproic Acid in Childhood Progressive Brain Tumors
5 Study of NGX-4010 for Treatment of Painful HIV-Associated Neuropathy
6 Treatment With Nab-paclitaxel in Cutaneous SCC
7 Chemotherapy, Radiotherapy and Bevacizumab in Patients With Unresectable Stage III Non-Small-Cell Lung Cancer
8 SOX as Salvage Treatment in Nasopharyngeal Carcinoma