Details of the Drug-Related molecule(s) Interaction Atlas

DB-053072 Drug Info

Methylglyoxylate; Pyruvate; Natriumpyruvat; Propanoic acid, 2-oxo-, ion(1-); Pyruvate ion; pyruvate; 10110-EP2277876A1; 10110-EP2292614A1; 10110-EP2295413A1; 10110-EP2295432A1; 10110-EP2295550A2; 10110-EP2298312A1; 10110-EP2308874A1; 10110-EP2311830A1; 10110-EP2316835A1; 2-Oxopropanoate; 2-oxidanylidenepropanoate; 2-oxo-Propanoic acid; 2-oxopropanoic acid, ion(1-); 2hzl; 57-60-3; BDBM50159792; CHEBI:15361; CHEMBL181886; CTK1H3219; DB-007695; DB-053072; DTXSID50205604; FT-0731491; HO43T60JMG; LCTONWCANYUPML-UHFFFAOYSA-M; UNII-HO43T60JMG

Cross-matching ID

PubChem CID

107735

ChEBI ID

CHEBI:15361

CAS Number

CAS 57-60-3

TTD Drug ID

DM1K248

INTEDE Drug ID

DR2449

General Information of Drug (ID: DM1K248)

Molecule-Related Drug Atlas

Molecule Type:

DME

Drug Status:

Investigative Drug(s)

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Drug(s) Metabolized By L-Lactate dehydrogenase (ldh)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Glucose-bisphosphate	DMMJQ7O	N. A.	N. A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
D-Lactate dehydrogenase (ldhA)	DEJEWXB	A0A1C7BXR3_PSEAI	Substrate	[1]
D-Lactate dehydrogenase (ldhA)	DECY6JG	LDHD_ECOLI	Substrate	[1]
Pyruvate oxidase (pyrO)	DE6QXYP	A0A0H0YI92_LACCA	Substrate	[2]
L-Lactate dehydrogenase (ldh)	DESR17C	LDH_LACCA	Substrate	[3]
L-Lactate dehydrogenase (ldh)	DE5DTYB	LDH_LACDB	Substrate	[4]
D-Lactate dehydrogenase (ldhA)	DEHUP0C	LDHD_LACDA	Substrate	[5]
D-Lactate dehydrogenase (ldhA)	DEBTUZ3	Q8RG11_FUSNN	Substrate	[1]

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References

1	Diverse allosteric and catalytic functions of tetrameric d-lactate dehydrogenases from three Gram-negative bacteria. AMB Express. 2014 Oct 28;4:76.
2	Metabolic gene-targeted monitoring of non-starter lactic acid bacteria during cheese ripening. Int J Food Microbiol. 2017 Sep 18;257:276-284.
3	Purification, properties and immunological relationship of L (+)-lactate dehydrogenase from Lactobacillus casei. Eur J Biochem. 1976 Aug 16;67(2):543-55.
4	Positive selection on D-lactate dehydrogenases of Lactobacillus delbrueckii subspecies bulgaricus. IET Syst Biol. 2015 Aug;9(4):172-9.
5	Cloning of D-lactate dehydrogenase genes of Lactobacillus delbrueckii subsp. bulgaricus and their roles in D-lactic acid production. 3 Biotech. 2017 Jul;7(3):194.