Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMD4381)

Drug Name
Terbutaline Drug Info
Synonyms
Asthmasian; Brethaire; Brethine; Brican; Bricanyl; Bricar; Bricaril; Bricyn; Terbutalin; Terbutalina; Terbutalino; Terbutalinum; Terbutalina [DCIT]; Terbutaline sulfate; KWD 2019; Asthmasian (TN); Brethaire (TN); Brethine (TN); Bricanyl (TN); KWD-2019; Terbutaline (INN); Terbutaline [INN:BAN]; Terbutalino [INN-Spanish]; Terbutalinum [INN-Latin]; (+-)-5-(2-((1,1-Dimethylethyl)amino)-1-hydroxyethyl)-1,3-benzenediol; (+-)-Terbutaline; 1,3-Benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-(9CI); 5-(2-((1,1-DIMETHYLETHYL)AMINO)-1-HYDROXYETHYL)-1,3-BENZENEDIOL; 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol; 5-{2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl}benzene-1,3-diol
Indication
Disease Entry ICD 11 Status REF
Asthma CA23 Approved [1]
Bronchitis CA20 Approved [2]
Pulmonary emphysema CA21.Z Approved [2]
Severe asthma CA23 Approved [2]
Pruritus EC90 Investigative [2]
Therapeutic Class
Bronchodilator Agents
Cross-matching ID
PubChem CID
5403
ChEBI ID
CHEMBL9449
CAS Number
CAS 23031-25-6
TTD Drug ID
DMD4381
VARIDT Drug ID
DR00971
ACDINA Drug ID
D00664

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Adrenergic receptor beta-2 (ADRB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indacaterol DMQJHR7 Chronic obstructive pulmonary disease CA22 Approved [10]
Formoterol DMSOURV Allergic asthma CA23.0 Approved [11]
Salbutamol DMN9CWF Acute asthma CA23 Approved [12]
Arformoterol DMYM974 Chronic obstructive pulmonary disease CA22 Approved [13]
Isoproterenol DMK7MEY Atrioventricular block Approved [14]
Salmeterol DMIEU69 Allergic asthma CA23.0 Approved [15]
Clenbuterol DMCKYZ5 Chronic breathing disorder 7A4Z Approved [16]
Ritodrine DM4V6RL Premature labour JB00 Approved [17]
Olodaterol DM62B78 Chronic obstructive pulmonary disease CA22 Approved [18]
Fenoterol DMIP3ZV Asthma CA23 Approved [19]
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Drug(s) Transported By Organic cation transporter 1 (SLC22A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [20]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [21]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [22]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [23]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [24]
Verapamil DMA7PEW Angina pectoris BA40 Approved [25]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [26]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [27]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [28]
Propranolol DM79NTF Angina pectoris BA40 Approved [29]
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Drug(s) Affected By Beta-2 adrenergic receptor (ADRB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salmeterol DMIEU69 Allergic asthma CA23.0 Approved [30]
Bambuterol DMKLSHF Asthma CA23 Approved [31]
Salbutamol DMN9CWF Acute asthma CA23 Approved [32]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [33]
Methotrexate DM2TEOL Anterior urethra cancer Approved [34]
Epinephrine DM3KJBC Acute asthma CA23 Approved [35]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [36]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [37]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [38]
Propranolol DM79NTF Angina pectoris BA40 Approved [39]
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Drug(s) Affected By Renin (REN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [40]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [41]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [42]
Reboxetine DM26PRD Depression 6A70-6A7Z Approved [43]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [44]
Ramipril DM2R68E Acute heart failure BD10-BD13 Approved [45]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [46]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [47]
Epinephrine DM3KJBC Acute asthma CA23 Approved [48]
Chlorthalidone DM4DMBT Edema MG29 Approved [49]
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Drug(s) Affected By Pulmonary surfactant-associated protein B (SFTPB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [50]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [51]
Leflunomide DMR8ONJ Arthritis FA20 Approved [52]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [8]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [53]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [54]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [53]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [53]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [55]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [55]
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Drug(s) Affected By Nuclear factor NF-kappa-B p105 subunit (NFKB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [56]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [57]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [58]
Gefitinib DM15F0X Colon adenocarcinoma Approved [59]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [60]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [61]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [63]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [64]
Quercetin DM3NC4M Obesity 5B81 Approved [65]
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Drug(s) Affected By Alpha-1D adrenergic receptor (ADRA1D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Alfuzosin DMZVMKF Benign prostatic hyperplasia GA90 Approved [66]
Verapamil DMA7PEW Angina pectoris BA40 Approved [67]
Epinephrine DM3KJBC Acute asthma CA23 Approved [68]
Oxymetazoline DM8ZXT6 Arrhythmia BC9Z Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Methoxamine DMF5XQH Hypertension BA00-BA04 Approved [69]
Quinidine DMLPICK N. A. N. A. Approved [67]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [5]
Norepinephrine DMOUC09 Alopecia ED70 Approved [69]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [71]
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Drug(s) Affected By Alpha-1B adrenergic receptor (ADRA1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [67]
Epinephrine DM3KJBC Acute asthma CA23 Approved [68]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [72]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [73]
Oxymetazoline DM8ZXT6 Arrhythmia BC9Z Approved [74]
Quinidine DMLPICK N. A. N. A. Approved [67]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [5]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [75]
Arsenic DMTL2Y1 N. A. N. A. Approved [76]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [77]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adrenergic receptor beta-2 (ADRB2) TT2CJVK ADRB2_HUMAN Agonist [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Organic cation transporter 1 (SLC22A1) DTT79CX S22A1_HUMAN Substrate [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alpha-1B adrenergic receptor (ADRA1B) OTSAYAFD ADA1B_HUMAN Gene/Protein Processing [5]
Alpha-1D adrenergic receptor (ADRA1D) OTW2CD1O ADA1D_HUMAN Gene/Protein Processing [5]
Beta-2 adrenergic receptor (ADRB2) OTSDOX4Q ADRB2_HUMAN Drug Response [6]
Nuclear factor NF-kappa-B p105 subunit (NFKB1) OTNRRD8I NFKB1_HUMAN Gene/Protein Processing [7]
Pulmonary surfactant-associated protein B (SFTPB) OTOHS07E PSPB_HUMAN Gene/Protein Processing [8]
Renin (REN) OT52GZR2 RENI_HUMAN Gene/Protein Processing [9]

References

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2 Terbutaline FDA Label
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