Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMKVOYF)

Drug Name
Penicillin V Drug Info
Synonyms
Apocillin; Apopen; Beromycin; Calcipen; Fenacilin; Fenospen; Fenossimetilpenicillina; Fenoximetilpenicilina; Fenoxymethylpenicillin; Fenoxypen; Meropenin; Oracillin; Oratren; Ospen; PNV; PVA; Phenocillin; Phenomycilline; Phenopenicillin; Phenoximethylpenicillinum; Phenoxomethylpenicillanyl; Phenoxomethylpenicillin; Phenoxymethylpenicillanyl; Phenoxymethylpenicillin; Phenoxymethylpenicilline; Phenoxymethylpenicillinum; Robicillin; Rocilin; Stabicillin; Vebecillin; Vegacillin; Acipen V; Compocillin V; Crystapen V; Distaquaine V; Eskacillian V; Eskacillin V; Fenossimetilpenicillina [DCIT]; Penicillin V [USAN]; Penicillin phenoxymethyl; Phenoxymethyl penicillin; Phenoxymethylenepenicillinic acid; Phenoxymethylpenicillinic acid; Phenoxymethylpenicillinic acid potassium salt; Acipen-v; Beromycin, Penicillin; Berromycin, Penicillin; Fenoximetilpenicilina [INN-Spanish]; Pen-Oral; Pen-V; Pen-vee; Penicillin V (USP); Penicillin, Phenoxymethyl; Phenoxymethylpenicillin (INN); Phenoxymethylpenicilline [INN-French]; Phenoxymethylpenicillinum [INN-Latin]; V-Cil; V-Cillin; V-Cylina; V-Cyline; V-Tablopen; P-Mega-Tablinen; V-Cillin (TN); (2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[(phenyloxy)acetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 2,2-dimethyl-6beta-[(phenoxyacetyl)amino]penam-3alpha-carbonyl; 2,2-dimethyl-6beta-[(phenoxyacetyl)amino]penam-3alpha-carboxylic acid; 3,3-Dimethyl-7-oxo-6-((phenyloxyacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid; 3,3-dimethyl-6beta-[(phenoxyacetyl)amino]penam-2alpha-carboxylic acid (PIN); 6-Phenoxyacetamidopenicillanic acid
Indication
Disease Entry ICD 11 Status REF
Acute otitis media AB00 Approved [1]
Bacterial infection 1A00-1C4Z Approved [2]
Erysipelas Approved [1]
Respiratory tract infection CA45 Approved [1]
Staphylococcus aureus infection Approved [1]
Therapeutic Class
Antibiotics
Cross-matching ID
PubChem CID
6869
ChEBI ID
CHEMBL27446
CAS Number
CAS 87-08-1
TTD Drug ID
DMKVOYF
VARIDT Drug ID
DR00868
ACDINA Drug ID
D00515

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Bacterial Penicillin binding protein (Bact PBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ampicillin DMHWE7P Acute epiglottitis Approved [6]
Cefazolin DMPDYFR Bacteremia 1A73 Approved [7]
Ceftriaxone DMCEW64 Acute gonococcal cervicitis Approved [8]
Ticarcillin DM4ME02 Aspiration pneumonia Approved [9]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [10]
Meropenem DM62UHC Bacterial infection 1A00-1C4Z Approved [8]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [11]
Clofarabine DMCVJ86 Acute lymphoblastic leukaemia 2A85 Approved [12]
Cephalexin DMD5JU8 Acute otitis media AB00 Approved [13]
Carbenicillin DMLEDNK Infection of the upper and lower urinary tract GC08 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glial fibrillary acidic protein (GFAP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [15]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [16]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [17]
Testosterone DM7HUNW Hot flushes GA30 Approved [18]
Haloperidol DM96SE0 Delirium Approved [19]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [20]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [21]
Ethanol DMDRQZU Chronic pain MG30 Approved [22]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pirin (PIR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [25]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [26]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [27]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [28]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [29]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [30]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [30]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [31]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [5]
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Drug(s) Affected By Tripartite motif-containing protein 16 (TRIM16)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [34]
Testosterone enanthate DMB6871 N. A. N. A. Approved [35]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [21]
Ampicillin DMHWE7P Acute epiglottitis Approved [5]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [36]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [37]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [38]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [39]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [40]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [41]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [42]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [43]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [44]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [45]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [46]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [48]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [46]
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Drug(s) Affected By Protein c-Fos (FOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [49]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [50]
Verapamil DMA7PEW Angina pectoris BA40 Approved [51]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [52]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [51]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [53]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [54]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [56]
Quercetin DM3NC4M Obesity 5B81 Approved [57]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Penicillin binding protein (Bact PBP) TTJP4SM NOUNIPROTAC Binder [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Glial fibrillary acidic protein (GFAP) OTQ01ZAS GFAP_HUMAN Drug Response [4]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Gene/Protein Processing [5]
Pirin (PIR) OT8ALXHU PIR_HUMAN Gene/Protein Processing [5]
Protein c-Fos (FOS) OTJBUVWS FOS_HUMAN Drug Response [4]
Tripartite motif-containing protein 16 (TRIM16) OTLRXYOZ TRI16_HUMAN Gene/Protein Processing [5]

References

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