Details of the Drug-Related molecule(s) Interaction Atlas

Genistein-7-glucoside Drug Info

1POG3SCN5T; 4',5,7-trihydroxyisoflavone 7-D-glucoside; BRN 0064479; C21H20O10; CHEBI:27514; Genistein 7-O-beta-D-glucoside; Genistein 7-glucoside; Genistein glucoside; Genistein, 7-O-beta-D-glucoside; Genistein, 7-beta-D-glucopyranoside; Genistein-7-glucoside; Genisteol 7-monoglucoside; Genistin; Genistine; Genistoside; Glucopyranoside, genistein-7, beta-D-; Glucosyl-7-genistein; Isoflavone, 4',5,7-trihydroxy-, 7-D-glucoside; MFCD00016883; NSC 5112; UNII-1POG3SCN5T; ZCOLJUOHXJRHDI-CMWLGVBASA-N; genistein 7-O-glucoside

Cross-matching ID

PubChem CID

5281377

ChEBI ID

CHEBI:27514

CAS Number

CAS 529-59-9

TTD Drug ID

DMMLNTW

VARIDT Drug ID

DR01318

General Information of Drug (ID: DMMLNTW)

Molecule-Related Drug Atlas

Molecule Type:

DTP

DOT

Drug Status:

Approved Drug(s)

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Drug(s) Transported By Multidrug resistance-associated protein 2 (ABCC2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[3]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[4]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[5]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[6]
Dinoprostone	DMTYOPD	Medical abortion	JA00.1Z	Approved	[7]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[8]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[9]
Sulfasalazine	DMICA9H	Irritable bowel syndrome	DD91.0	Approved	[10]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[11]
Oxaliplatin	DMQNWRD	Adenocarcinoma	2D40	Approved	[12]
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Drug(s) Affected By Metallothionein-2 (MT2A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[13]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[14]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[15]
Deoxycholic acid	DM3GYAL	Subcutaneous fat disorder	EF02	Approved	[16]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[17]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[18]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[19]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[20]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[21]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[22]
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Drug(s) Affected By Metallothionein-1A (MT1A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[13]
Salicyclic acid	DM2F8XZ	Acne vulgaris	ED80	Approved	[23]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[24]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[25]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[26]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[27]
Benzoic Acid	DMKB9FI	Alopecia areata	ED70.2	Approved	[23]
Sodium lauryl sulfate	DMLJ634	Constipation	DD91.1	Approved	[23]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[28]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[29]
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Drug(s) Affected By Metallothionein-1E (MT1E)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[30]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[19]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[24]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[31]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[32]
Motexafin gadolinium	DMEJKRF	Brain cancer	2A00	Approved	[33]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[34]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[35]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[36]
Amiodarone	DMUTEX3	Tachyarrhythmias	BC71	Approved	[37]
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Drug(s) Affected By Glucose-6-phosphate 1-dehydrogenase (G6PD)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[38]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[39]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[40]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[41]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[42]
Clavulanate	DM2FGRT	Bacteremia	1A73	Approved	[43]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[44]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[45]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[46]
Isoniazid	DM5JVS3	Latent tuberculosis infection		Approved	[47]
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Drug(s) Affected By Metallothionein-1X (MT1X)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[30]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[15]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[44]
Penicillamine	DM40EF6	Cystinuria	5C60.2	Approved	[48]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[49]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[19]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[20]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[50]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[50]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[31]
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Drug(s) Affected By Proton-coupled zinc antiporter SLC30A1 (SLC30A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[14]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[51]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[44]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[52]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[53]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[46]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[19]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[54]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[55]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[56]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Multidrug resistance-associated protein 2 (ABCC2)	DTFI42L	MRP2_HUMAN	Substrate	[1]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Glucose-6-phosphate 1-dehydrogenase (G6PD)	OT300SMK	G6PD_HUMAN	Gene/Protein Processing	[2]
Metallothionein-1A (MT1A)	OTKBH52X	MT1A_HUMAN	Gene/Protein Processing	[2]
Metallothionein-1E (MT1E)	OTXJKU4Y	MT1E_HUMAN	Gene/Protein Processing	[2]
Metallothionein-1X (MT1X)	OT9AKFVS	MT1X_HUMAN	Gene/Protein Processing	[2]
Metallothionein-2 (MT2A)	OTHOACHD	MT2_HUMAN	Gene/Protein Processing	[2]
Proton-coupled zinc antiporter SLC30A1 (SLC30A1)	OTY8J0S4	ZNT1_HUMAN	Gene/Protein Processing	[2]

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