Details of the Drug

General Information of Drug (ID: DMH0ZJE)

• Drug Name: Mitomycin
• Synonyms: Mitomycin C; mitomycin C; 1950/7/7; Mutamycin; Ametycine; Mitocin-C; Ametycin; Mitomycin-C; Mytozytrex; Mitomycinum; Mytomycin; Mitozytrex; Mitomycinum C; Mitocin C; Mitomycins; Mitamycin; MMC; Mitosol; Mitomycyna C; 7-Amino-9alpha-methoxymitosane; NSC-26980; Mitomycyna C [Polish]; Mito-C; Mit-C; Mitomycin (TN); Mitomycinum [INN-Latin]; Mitomycine [INN-French]; Mitomicina [INN-Spanish]; NCI-C04706; RCRA waste number U010; NSC26980; NSC 26980; Mitomycine; CCRIS 414; UNII-50SG953SK6; HSDB 3239; C15H18N4O5; EINECS 200-008-6; Mitomycin C,; Ametycin; Mitomicina; Muamycin; Mitomycin C from Streptomyces caespitosus; Mitomycin C (JP15); Mitomycin C, Streptomyces caespitosus; Muamycin (TN); Mitomycin (USP/INN); Mitomycin [USAN:INN:BAN]; Mitomycin C, Streptomyces caespitosus, Carrier-Free

Indication

Disease Entry	ICD 11	Status	REF
Breast cancer	2C60-2C65	Approved	[1]
Gastrointestinal cancer	2C11	Approved	[1]
Pancreatic adenocarcinoma	N.A.	Approved	[2]
Solid tumour/cancer	2A00-2F9Z	Approved	[3]
Urinary bladder cancer	N.A.	Approved	[2]
Urinary bladder neoplasm	N.A.	Approved	[2]
Urinary system neoplasm	N.A.	Approved	[2]
Urinary tract disease	GC2Z	Approved	[2]
Bladder disease	DC11-DC1Z	Investigative	[2]
Colon cancer	2B90.Z	Investigative	[2]

• Therapeutic Class: Anticancer Agents
• Affected Organisms: Humans and other mammals
• ATC Code:
  L01DC03: Mitomycin
  L01DC: Other cytotoxic antibiotics
  L01D: CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
  L01: ANTINEOPLASTIC AGENTS
  L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 334.33
  Logarithm of the Partition Coefficient (xlogp); -0.4
  Rotatable Bond Count (rotbonds); 4
  Hydrogen Bond Donor Count (hbonddonor); 3
  Hydrogen Bond Acceptor Count (hbondacc); 8
• ADMET Property:
  Absorption: The drug is unstablely absorbed []
  Half-life: The concentration or amount of drug in body reduced by one-half in 8 - 48 minutes [4]
  Metabolism: The drug is metabolized via the hepatic []
• Chemical Identifiers:
  Formula: C15H18N4O5
  IUPAC Name: [(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
  Canonical SMILES: CC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@@H]2COC(=O)N)OC)N4)N
  InChI: InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
  InChIKey: NWIBSHFKIJFRCO-WUDYKRTCSA-N
• Cross-matching ID:
  PubChem CID: 5746
  ChEBI ID: CHEBI:27504
  CAS Number: 50-07-7
  UNII: 50SG953SK6
  DrugBank ID: DB00305
  TTD ID: D0Y0GH
  VARIDT ID: DR01212
  ACDINA ID: D01255
• Repurposed Drugs (RPD): Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Human Deoxyribonucleic acid (hDNA)	TTUTN1I	NOUNIPROTAC	Binder	[5]

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[6]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
A-kinase anchor protein 12 (AKAP12)	OTCVRDDX	AKA12_HUMAN	Drug Response	[7]
Acid ceramidase (ASAH1)	OT1DNGXL	ASAH1_HUMAN	Drug Response	[7]
Actin-binding LIM protein 1 (ABLIM1)	OTHXEK3E	ABLM1_HUMAN	Drug Response	[7]
Activated RNA polymerase II transcriptional coactivator p15 (SUB1)	OTK71JYU	TCP4_HUMAN	Gene/Protein Processing	[8]
Acyl-coenzyme A thioesterase 2, mitochondrial (ACOT2)	OTAKUO27	ACOT2_HUMAN	Drug Response	[7]
Acylamino-acid-releasing enzyme (APEH)	OTX258QE	ACPH_HUMAN	Drug Response	[7]
Adhesion G-protein coupled receptor G1 (ADGRG1)	OTQBB8NT	AGRG1_HUMAN	Drug Response	[7]
Aldehyde dehydrogenase, dimeric NADP-preferring (ALDH3A1)	OTAYZZE6	AL3A1_HUMAN	Drug Response	[9]
Aldehyde oxidase (AOX1)	OT2FZP6H	AOXA_HUMAN	Drug Response	[7]
Alternative prion protein (PRNP)	OTE85L1Q	APRIO_HUMAN	Gene/Protein Processing	[8]

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Bone Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
RPMI-3460/CS1	GDSC1	1.1064	5.2224	0.4406	39.2141
ES7	GDSC1	-5.4931	-1.158	-5.525	90.7121
MHH-ES-1	GDSC1	-5.1233	-0.977	-5.1531	89.8275
EW-16	GDSC1	-4.9996	-1.2634	-5.0166	90.7158
EW-7	GDSC1	-4.837	-0.5139	-4.8806	87.9059
SK-ES-1	GDSC1	-4.8296	-0.2429	-4.8896	86.9634
ES1	GDSC1	-4.433	-1.6324	-4.4364	91.4553
ES4	GDSC1	-4.3465	-1.0313	-4.3584	89.0431
ES8	GDSC1	-4.2052	-2.2849	-4.2054	93.636
EW-13	GDSC1	-4.0151	-0.6397	-4.0317	86.8878
EW-3	GDSC1	-3.4729	3.0807	-3.924	73.6434
SK-PN-DW	GDSC1	-3.4659	-0.8508	-3.4704	86.0064
EW-1	GDSC1	-3.3432	0.7332	-3.4128	79.8981
MHH-ES-1	CTRP2	-2.9051	-0.341	-2.9067	56.8747
SJSA-1	GDSC1	-2.8488	1.0048	-2.9181	76.8861
SK-N-MC	CTRP2	-2.5722	-1.4225	-2.5722	54.6838
HOS	GDSC1	-2.495	-0.2797	-2.4982	78.6527
A-673	CTRP2	-1.9851	1.4032	-2.0068	50.7642
EW-11	GDSC1	-1.3633	4.215	-1.9132	61.0471
ES5	GDSC1	-1.0824	3.9061	-1.5213	59.4743
TC71	CTRP2	-0.8804	2.4411	-0.9202	43.5208
SaOS-2	GDSC1	-0.4795	6.1276	-1.5986	53.4817
A-673	GDSC1	-0.4364	2.1761	-0.4921	55.0832
NY	GDSC1	-0.429	2.786	-0.5644	54.7009
ES6	GDSC1	-0.3951	3.246	-0.6136	54.1214
U2OS	CTRP2	-0.3472	4.3808	-0.5978	40.5195
EW-24	GDSC1	-0.2933	1.6174	-0.3057	53.5917
H-EMC-SS	GDSC1	-0.0551	4.0498	-0.4392	50.5442
TC-71	GDSC1	0.1304	2.003	0.1124	48.3994
NOS-1 [Human HNSCC]	GDSC1	0.6319	4.7696	0.0887	43.81
EW-18	GDSC1	0.6474	3.4255	0.4805	42.5896
HuO9	GDSC1	0.7932	7.3731	-0.7701	44.2364
U2OS	GDSC1	0.8491	4.2967	0.4759	40.985
SJSA-1	CTRP2	1.9164	4.8516	1.7617	25.3368
MG-63	GDSC1	1.9745	10.8276	-1.2202	38.8407
CHSA0108	GDSC1	2.4625	6.0272	1.5314	25.4879
SW1353	CTRP2	2.588	4.9733	2.4652	20.759
HuO-3N1	GDSC1	2.7586	4.3552	2.534	17.0287
CHSA0011	GDSC1	3.4593	5.1334	2.9375	10.5671
MG-63	CTRP2	4.0881	6.8627	3.5077	12.5058
CAL-78	CTRP2	4.4488	6.6128	3.9894	9.6594
HOS	CTRP2	4.576	7.3271	3.8041	10.0656
G-292 clone A141B1	CTRP2	4.6947	8.1636	3.5261	10.9087
CAL-78	GDSC1	4.7565	7.5865	2.7914	7.0975
CAL-72	GDSC1	4.9648	15.034	-0.7351	26.4175
G-292 clone A141B1	GDSC1	5.1087	7.9526	2.8537	5.7115
CHSA8926	GDSC1	5.1252	9.3131	2.2127	10.307
SaOS-2	CTRP2	5.469	6.3686	5.1271	2.5326
Hs 888.T	CTRP2	5.9037	8.4962	4.428	4.626
Hs 822.T	CTRP2	6.797	7.6465	5.3662	0.1272

Cancer Drug Sensitivity Data Curated from 292 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JK1	CTRP2	-3.0441	1.7752	-3.1261	57.3099
MEC1	CTRP2	1.1031	3.8658	1.0369	30.4433
JM1	GDSC1	-2.9483	-0.8576	-2.9496	83.46
JM1	CTRP2	-1.6904	0.4208	-1.6913	48.8155
Kasumi-2	CTRP2	-5.9686	-3.2822	-5.9687	76.8049
MV4-11	CTRP2	-5.7464	-3.1868	-5.7466	75.4759
MV4-11	GDSC1	-5.2936	-2.4663	-5.2954	94.996
OCI-Ly19	GDSC1	-5.187	-1.0332	-5.2161	90.0758
NKM-1	GDSC1	-5.1197	-0.6888	-5.163	88.8388
MOLT-16	CTRP2	-5.0061	-2.8552	-5.0062	70.8091
KE-37	GDSC1	-4.9123	-1.9272	-4.9161	93.0148
SR	GDSC1	-4.9018	-1.2072	-4.9186	90.4259
MHH-CALL-4	CTRP2	-4.7752	-1.8552	-4.7762	69.0776
ML-2	GDSC1	-4.7357	-1.1901	-4.75	90.1867
NALM-6	GDSC1	-4.6484	-2.8253	-4.6485	96.0915
NB4	GDSC1	-4.6031	-1.5252	-4.6091	91.2675
697	GDSC1	-4.52	-2.7186	-4.5201	95.64
Mino	CTRP2	-4.5138	16.2904	-9.449	56.603
OCI-AML-2	GDSC1	-4.4751	-1.9031	-4.4767	92.5382
Granta-519	CTRP2	-4.3897	0.3772	-4.4319	65.5427
SUP-B15	GDSC1	-4.3866	-1.8892	-4.388	92.3726
EoL-1	CTRP2	-4.3186	-1.6313	-4.3193	66.1809
NU-DUL-1	GDSC1	-4.2595	-0.949	-4.272	88.576
P30/OHK	GDSC1	-4.1178	-2.2949	-4.1179	93.5224
Hs 445	GDSC1	-4.097	-1.5541	-4.0991	90.5795
Loucy	GDSC1	-4.0305	-1.8133	-4.0312	91.4506
KE-37	CTRP2	-4.0134	-2.7669	-4.0134	64.276
ALL-PO	GDSC1	-3.973	-0.6125	-3.9895	86.6828
SIG-M5	GDSC1	-3.9644	-2.2241	-3.9645	92.9129
MOLT-3	CTRP2	-3.9266	-1.8798	-3.9266	63.6805
BE-13	GDSC1	-3.9146	-2.6696	-3.9146	94.5369
MOLT-4	GDSC1	-3.9089	-2.5602	-3.9089	94.0912
Reh	GDSC1	-3.9066	-2.4386	-3.9066	93.607
IM-9	GDSC1	-3.8836	-1.2684	-3.8867	88.9618
CCRF-CEM	GDSC1	-3.8829	-1.4187	-3.8849	89.5442
WIL2 NS	GDSC1	-3.8621	-0.9487	-3.8691	87.671
SU-DHL-5	GDSC1	-3.8458	-2.7116	-3.8458	94.4921
NALM-6	CTRP2	-3.8352	-2.2479	-3.8352	63.0877
ALL-SIL	GDSC1	-3.8266	-1.2328	-3.8297	88.6677
RPMI-8402	GDSC1	-3.7908	-0.6331	-3.8035	86.2727
DoHH2	CTRP2	-3.7803	-1.0288	-3.7817	62.6344
OCI-AML-3	CTRP2	-3.7627	-0.5417	-3.7675	62.4145
NU-DUL-1	CTRP2	-3.6678	-1.2487	-3.6683	61.9367
RS4;11	GDSC1	-3.666	-1.3189	-3.6676	88.5051
DEL	GDSC1	-3.5959	-0.719	-3.6038	85.9851
KOPN-8	GDSC1	-3.5908	0.351	-3.6422	82.0767
HAL-01	GDSC1	-3.5733	-1.9972	-3.5734	90.7276
SUP-M2	CTRP2	-3.559	-0.4232	-3.5635	61.1072
P12-Ichikawa	GDSC1	-3.5346	-1.6853	-3.5348	89.4031
MOLM-13	CTRP2	-3.5338	-0.5434	-3.537	60.9721
CTV-1	GDSC1	-3.5038	-1.4368	-3.5044	88.3478
OCI-Ly19	CTRP2	-3.4482	0.2048	-3.4622	60.2533
BC-1	GDSC1	-3.4384	-0.1232	-3.4601	83.2284
Karpas-231	GDSC1	-3.4319	-2.079	-3.4319	90.3232
BV-173	CTRP2	-3.3712	-0.4919	-3.3739	59.9223
KMS-21-BM	CTRP2	-3.3326	-0.2413	-3.3374	59.6343
A3/Kawakami	GDSC1	-3.314	-1.6299	-3.3141	88.1435
DoHH2	GDSC1	-3.2838	-0.64	-3.2895	84.4773
SU-DHL-1	CTRP2	-3.2517	-1.7052	-3.2517	59.2057
SCC-3	GDSC1	-3.2491	-2.4285	-3.2491	90.0272
WSU-DLCL2	GDSC1	-3.2357	1.8411	-3.429	76.0443
CML-T1	CTRP2	-3.2314	-1.3862	-3.2314	59.0676
RS4;11	CTRP2	-3.2162	-1.2347	-3.2163	58.9639
RPMI-8402	CTRP2	-3.1744	-1.3231	-3.1744	58.6882
JSC-1	GDSC1	-3.1654	-0.801	-3.1681	84.4903
HL-60	GDSC1	-3.1406	-0.9653	-3.142	84.9292
697	CTRP2	-3.0668	-1.4184	-3.0668	57.9744
P12-Ichikawa	CTRP2	-2.9684	-0.9264	-2.9685	57.3148
NK-92MI	GDSC1	-2.9292	1.6322	-3.0716	75.3724
Ku812	GDSC1	-2.9249	1.556	-3.0572	75.5759
QIMR-WIL	GDSC1	-2.9119	-1.2007	-2.9122	84.249
SUP-T1	GDSC1	-2.9084	1.1696	-2.9961	76.6622
KM-H2	GDSC1	-2.9058	0.2585	-2.9294	79.5627
OCI-AML-5	GDSC1	-2.9011	0.035	-2.9163	80.2753
Daudi	CTRP2	-2.8928	1.3524	-2.9388	56.5316
HEL	GDSC1	-2.8789	-0.8101	-2.8802	82.8701
RCH-ACV	CTRP2	-2.8624	0.4992	-2.8742	56.5119
EoL-1	GDSC1	-2.8485	-0.6999	-2.8503	82.3351
SUP-B15	CTRP2	-2.8443	-0.7794	-2.8445	56.4894
MY-M12	GDSC1	-2.8262	-0.706	-2.8278	82.2075
SU-DHL-1	GDSC1	-2.8172	-1.0412	-2.8175	83.1135
MHH-CALL-3	CTRP2	-2.8082	2.6408	-2.9672	55.6657
EB2	GDSC1	-2.8008	-0.5019	-2.8039	81.4199
L-540	GDSC1	-2.7905	-0.0854	-2.8004	80.0491
DND-41	GDSC1	-2.776	-0.7351	-2.7773	81.9534
Mono-Mac-6	GDSC1	-2.7733	0.4572	-2.8024	78.222
JURL-MK1	CTRP2	-2.7305	-0.0159	-2.7333	55.709
BALL-1	GDSC1	-2.7057	0.5145	-2.7355	77.6691
VAL	GDSC1	-2.7005	0.5894	-2.7342	77.4071
HC-1	GDSC1	-2.694	0.0947	-2.7069	78.9086
SU-DHL-8	GDSC1	-2.659	-0.9941	-2.6592	81.7487
Namalwa	GDSC1	-2.6369	-0.8593	-2.6374	81.2436
H9	GDSC1	-2.63	0.0499	-2.6406	78.6482
Mono-Mac-1	CTRP2	-2.6125	1.3102	-2.6472	54.8026
P32/ISH	GDSC1	-2.5723	-1.5135	-2.5723	81.8502
VL51	GDSC1	-2.5501	1.0051	-2.6056	75.3035
MOLM-6	CTRP2	-2.5132	2.0178	-2.5907	54.0689
WSU-NHL	GDSC1	-2.3444	2.0434	-2.5044	71.2843
SET-2	CTRP2	-2.3383	0.4392	-2.3428	53.11
CESS	GDSC1	-2.3262	-0.7558	-2.3264	78.259
JURL-MK1	GDSC1	-2.2973	1.2196	-2.3588	73.1717
TUR	GDSC1	-2.2955	-0.3748	-2.2968	77.2486
Granta-519	GDSC1	-2.2666	1.5054	-2.3535	72.2163
A4/Fukuda	GDSC1	-2.2507	1.5515	-2.3416	71.9966
KM-H2	CTRP2	-2.2038	1.1296	-2.2209	52.2002
RPMI-6666	GDSC1	-2.1775	1.4814	-2.2571	71.7125
BV-173	GDSC1	-2.1635	3.7979	-2.6723	66.4367
NOMO-1	GDSC1	-2.1575	-0.1608	-2.1595	75.5763
EB1	CTRP2	-2.1539	1.334	-2.177	51.866
ALL-SIL	CTRP2	-2.1486	-0.0692	-2.1491	51.8629
BC-3	GDSC1	-2.1362	1.0595	-2.1784	72.5141
GR-ST	GDSC1	-2.1266	3.2859	-2.5056	67.2332
NU-DHL-1	CTRP2	-2.1091	1.6064	-2.1433	51.5641
MOLM-13	GDSC1	-2.097	2.2687	-2.2737	69.2745
EM-2	CTRP2	-2.0907	0.135	-2.0917	51.4774
SU-DHL-8	CTRP2	-2.0387	0.0049	-2.0391	51.132
ATN-1	GDSC1	-2.0375	-1.1132	-2.0375	75.419
Farage	GDSC1	-2.0086	0.9616	-2.04	71.8179
TK [Human B-cell lymphoma]	GDSC1	-1.9839	1.1938	-2.0293	71.0789
PF-382	GDSC1	-1.9031	0.3769	-1.9101	72.2184
ARH-77	GDSC1	-1.8635	1.556	-1.9338	69.3448
CTB-1	GDSC1	-1.8555	2.6534	-2.0794	66.9016
OCI-AML-5	CTRP2	-1.7989	0.6988	-1.8021	49.538
OCI-AML-2	CTRP2	-1.7879	1.8765	-1.8262	49.4753
HEL 92.1.7	CTRP2	-1.7863	1.4454	-1.805	49.4596
MOLP-8	GDSC1	-1.7791	1.4863	-1.8388	68.8549
SUP-T11	CTRP2	-1.7316	0.2055	-1.732	49.0891
Namalwa	CTRP2	-1.7289	0.6396	-1.7312	49.0728
OCI-AML-3	GDSC1	-1.7269	2.5787	-1.9271	66.1903
A3/Kawakami	CTRP2	-1.715	-0.4372	-1.715	48.9784
DEL	CTRP2	-1.6955	-0.0912	-1.6955	48.8486
TALL-1 [Human adult T-ALL]	CTRP2	-1.6463	3.4277	-1.835	48.6315
BL-41	GDSC1	-1.644	0.0393	-1.6449	70.1233
GA-10	CTRP2	-1.6223	2.6002	-1.7079	48.4258
JVM-3	CTRP2	-1.5852	0.3965	-1.5858	48.1155
L-540	CTRP2	-1.5694	-0.1642	-1.5694	48.0096
GDM-1	GDSC1	-1.5545	4.8537	-2.3147	61.392
HEL	CTRP2	-1.538	-0.5871	-1.538	47.8003
SUP-T1	CTRP2	-1.5239	8.929	-3.2695	48.491
P31/FUJ	CTRP2	-1.5129	2.151	-1.5579	47.6853
CMK	CTRP2	-1.4636	0.8096	-1.4657	47.3089
KE-97	CTRP2	-1.4605	2.2923	-1.513	47.3509
Daudi	GDSC1	-1.4565	1.7624	-1.5255	65.671
WSU-DLCL2	CTRP2	-1.4463	1.0422	-1.4506	47.1974
OCI-Ly3	CTRP2	-1.4293	0.6798	-1.4305	47.0791
NCO2	CTRP2	-1.414	1.8964	-1.4415	47.0165
KMS-20	CTRP2	-1.39	3.605	-1.5872	47.0423
SUP-M2	GDSC1	-1.3821	0.8311	-1.3917	66.4338
JVM-2	GDSC1	-1.3127	3.2921	-1.6211	61.9935
SU-DHL-6	CTRP2	-1.2972	1.3558	-1.3049	46.2134
DB	GDSC1	-1.2945	1.8176	-1.3604	64.1532
MOLP-8	CTRP2	-1.2765	2.1287	-1.3117	46.1225
HuT 78	CTRP2	-1.2526	3.7626	-1.4648	46.198
SUP-HD1	GDSC1	-1.227	2.2285	-1.3364	62.9221
Hs 611.T	CTRP2	-1.2246	2.0875	-1.2559	45.7745
DB	CTRP2	-1.2167	3.7948	-1.4316	45.9764
YT	GDSC1	-1.2005	3.0933	-1.4561	61.427
SU-DHL-16	GDSC1	-1.1893	2.2111	-1.294	62.6164
KO52	CTRP2	-1.1354	1.3663	-1.1413	45.1353
KMS-34	CTRP2	-1.1041	1.1725	-1.1072	44.9205
Ku812	CTRP2	-1.0952	1.8758	-1.1136	44.8948
ST486	GDSC1	-1.0581	2.1618	-1.1482	61.489
MC116	CTRP2	-1.011	3.2904	-1.1375	44.5406
SU-DHL-4	CTRP2	-0.9504	2.2844	-0.9834	43.9678
A4/Fukuda	CTRP2	-0.9134	2.9447	-0.9953	43.8252
AMO1	GDSC1	-0.9104	1.4712	-0.9335	60.7636
KG-1	GDSC1	-0.8652	2.3447	-0.9662	59.4372
PF-382	CTRP2	-0.8348	1.8005	-0.8456	43.1497
THP-1	GDSC1	-0.7595	2.1661	-0.8321	58.5548
Jurkat	CTRP2	-0.7564	0.6944	-0.7565	42.5987
SU-DHL-10	CTRP2	-0.7537	3.1849	-0.852	42.8157
MOLT-16	GDSC1	-0.7528	1.2377	-0.7623	59.1591
EHEB	CTRP2	-0.739	3.5745	-0.8854	42.8198
L-363	GDSC1	-0.6913	2.5903	-0.8152	57.4982
Ki-JK	CTRP2	-0.6561	2.1019	-0.6726	41.9779
DND-41	CTRP2	-0.6529	1.6193	-0.6576	41.9239
EHEB	GDSC1	-0.6472	2.888	-0.817	56.8206
SIG-M5	CTRP2	-0.6133	1.2955	-0.6146	41.6503
LAMA-84	GDSC1	-0.5842	2.5403	-0.6932	56.4562
OCI-M1	GDSC1	-0.5499	0.6541	-0.5502	56.8631
Jiyoye	GDSC1	-0.5303	2.8384	-0.6822	55.7051
MEG-01	GDSC1	-0.5254	2.6113	-0.6406	55.8021
MOTN-1	CTRP2	-0.5135	2.5905	-0.5492	41.0835
KMS-27	CTRP2	-0.4773	1.8406	-0.4837	40.7606
LAMA-84	CTRP2	-0.4153	2.5005	-0.4426	40.4089
RPMI-6666	CTRP2	-0.3839	2.5662	-0.4138	40.2081
Peer	CTRP2	-0.3336	3.088	-0.3992	39.9739
AML-193	CTRP2	-0.3062	2.3187	-0.3225	39.6523
SU-DHL-6	GDSC1	-0.2974	2.4428	-0.3745	53.4259
U266B1	GDSC1	-0.2937	2.6285	-0.3951	53.323
KCL-22	GDSC1	-0.287	2.8022	-0.4143	53.1909
SUP-HD1	CTRP2	-0.2779	2.545	-0.3032	39.491
Sc-1	GDSC1	-0.1949	3.7582	-0.5144	51.9601
M-07e	CTRP2	-0.1912	2.608	-0.2171	38.9167
AMO1	CTRP2	-0.1705	2.1087	-0.1781	38.7232
Karpas-422	GDSC1	-0.1572	2.1834	-0.1994	51.8754
HuNS1	CTRP2	-0.1193	2.1517	-0.1271	38.383
KYO-1	CTRP2	-0.1038	1.9772	-0.1082	38.269
EM-2	GDSC1	-0.0724	4.5939	-0.6196	50.6659
NB4	CTRP2	-0.0554	1.9166	-0.0585	37.9426
HL-60	CTRP2	-0.0368	2.2112	-0.0447	37.8341
CA46	GDSC1	-0.0138	3.2673	-0.2043	50.1501
KHM-1B	CTRP2	0.0111	3.3173	-0.0586	37.7052
HH [Human lymphoma]	GDSC1	0.0531	3.5926	-0.2033	49.4382
LC4-1	GDSC1	0.0632	3.3957	-0.1477	49.3155
KMS-26	CTRP2	0.0756	3.0262	0.0337	37.1934
KMS-12-BM	CTRP2	0.0829	2.6108	0.0647	37.071
MJ	CTRP2	0.0839	5.4084	-0.3613	38.2337
Reh	CTRP2	0.1077	2.8482	0.0786	36.9405
Ri-1	CTRP2	0.1601	3.0472	0.1202	36.6261
SR	CTRP2	0.1746	2.9266	0.1432	36.503
KMOE-2	GDSC1	0.2761	2.4285	0.2333	46.6642
KMS-12-BM	GDSC1	0.3087	2.7331	0.2336	46.3435
RPMI-8226	GDSC1	0.3143	2.2382	0.2886	46.154
L-428	GDSC1	0.3159	3.3414	0.1382	46.4642
MN-60	GDSC1	0.3168	3.8597	0.0178	46.655
HDLM-2	GDSC1	0.3476	3.9779	0.0201	46.3679
KCL-22	CTRP2	0.3801	3.9693	0.2548	35.4312
MLMA	GDSC1	0.4168	2.4582	0.3783	44.9337
MC116	GDSC1	0.4208	2.4179	0.386	44.8719
Raji	GDSC1	0.4228	3.1027	0.2993	45.1057
Karpas-299	GDSC1	0.4391	2.0541	0.4276	44.5613
HDLM-2	CTRP2	0.4526	4.0075	0.3269	34.9534
RPMI-8866	GDSC1	0.4754	1.4791	0.475	44.0594
Mono-Mac-6	CTRP2	0.5134	12.5035	-2.6366	40.6329
OCI-Ly10	CTRP2	0.5481	4.3302	0.3784	34.4589
L-428	CTRP2	0.5907	3.0282	0.5676	33.709
RC-K8	GDSC1	0.6135	2.549	0.5765	42.5066
PL-21	GDSC1	0.6203	4.7371	0.0869	43.9071
U-698-M	GDSC1	0.6354	2.4906	0.6045	42.2088
HT	GDSC1	0.6372	2.0359	0.6308	42.0696
NCI-H929	CTRP2	0.6546	2.7576	0.6442	33.2414
HT	CTRP2	0.7133	3.1639	0.6868	32.904
KY821	GDSC1	0.7146	3.4836	0.5412	41.8192
HD-MY-Z	CTRP2	0.7569	3.7845	0.6796	32.7812
Karpas-422	CTRP2	0.7728	2.6557	0.767	32.4399
SU-DHL-4	GDSC1	0.8001	2.0249	0.7965	40.0204
SKM-1	CTRP2	0.8272	3.3702	0.7917	32.1764
HPB-ALL	CTRP2	0.8642	3.4127	0.8271	31.9353
L-1236	GDSC1	0.928	3.3384	0.8021	39.0563
K-562	GDSC1	0.9316	3.4311	0.7877	39.0975
EJM	GDSC1	0.9711	3.1249	0.8857	38.3302
Karpas-620	GDSC1	0.9888	2.993	0.924	38.0042
ST486	CTRP2	1.0022	4.4622	0.8451	31.415
CA46	CTRP2	1.0091	4.4563	0.8535	31.3642
Kasumi-1	CTRP2	1.0361	2.2295	1.0359	30.6685
MOLM-16	CTRP2	1.0503	2.8426	1.0445	30.5926
Ramos.2G6.4C10	GDSC1	1.0607	2.5211	1.0449	36.8362
EJM	CTRP2	1.2102	3.9311	1.143	29.7344
OPM-2	CTRP2	1.2389	3.6571	1.1994	29.45
JeKo-1	CTRP2	1.2636	3.2652	1.2489	29.2029
Karpas-299	CTRP2	1.2827	3.9265	1.2202	29.2359
Karpas-45	GDSC1	1.3027	3.0865	1.2462	34.061
NOMO-1	CTRP2	1.3189	3.5367	1.2914	28.8777
Pfeiffer	CTRP2	1.3423	2.0779	1.3423	28.6301
SK-MM-2	GDSC1	1.3733	4.1766	1.0833	34.5142
MHH-PREB-1	GDSC1	1.3772	3.8182	1.1852	33.9272
JVM-3	GDSC1	1.3778	3.0233	1.3339	33.0489
TF-1	CTRP2	1.3966	3.6634	1.3635	28.3794
P3HR-1	CTRP2	1.3992	3.9775	1.3378	28.4572
ROS-50	GDSC1	1.4655	3.702	1.3093	32.6357
JVM-2	CTRP2	1.5133	4.1502	1.4389	27.7423
OCI-M1	CTRP2	1.5177	2.4225	1.5176	27.4629
JJN-3	CTRP2	1.5245	6.3136	0.949	29.3616
Raji	CTRP2	1.5665	4.094	1.5019	27.3551
ME1	GDSC1	1.5731	4.5438	1.1852	32.6624
Ci-1	CTRP2	1.6149	2.5975	1.6148	26.8159
P31/FUJ	GDSC1	1.7456	3.4005	1.6737	28.6354
JJN-3	GDSC1	1.7979	4.3302	1.4991	29.4207
RL	CTRP2	1.8361	4.3462	1.7573	25.6098
LP-1	GDSC1	1.9691	3.4545	1.9052	25.7935
KMS-11	CTRP2	2.0744	4.3013	2.0162	23.9537
PL21	CTRP2	2.1169	3.8636	2.0983	23.5369
BL-70	CTRP2; CTRP1	2.2242	5.2234	2.0177	23.4718
RPMI-8226	CTRP2	2.2491	4.3168	2.1994	22.7621
LP-1	CTRP2	2.3398	5.0798	2.1749	22.5572
F-36P	CTRP2	2.3523	4.7853	2.2444	22.2753
OPM-2	GDSC1	2.3792	4.9235	1.9148	23.3931
DG-75	GDSC1	2.4075	4.0659	2.2436	20.9843
SK-MM-2	CTRP2	2.4133	3.9354	2.4004	21.5447
MOLP-2	CTRP2	2.4504	4.1035	2.4292	21.3258
L-363	CTRP2	2.4743	5.7741	2.1484	22.2349
RL	GDSC1	2.4847	3.7814	2.4005	19.4864
U-937	CTRP2	2.7568	6.1323	0.2364	5.4722
U266B1	CTRP2	3.021	4.7375	2.9684	17.6353
GDM-1	CTRP2	3.0704	4.4295	3.0514	17.1917
MM1.S	CTRP2	3.2897	8.8394	-0.7011	9.4338
THP-1	CTRP2	3.439	11.859	-2.0647	15.6686
ME1	CTRP2	3.5664	4.6725	3.5504	13.8808
L-1236	CTRP2	3.5667	12.3451	-2.21	16.0232
KMS-18	CTRP2	3.5886	4.8212	3.5605	13.774
REC-1	CTRP2	5.4822	12.413	2.1237	14.9091

Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Oesophagus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TE15	CTRP2	-0.1192	3.4987	-0.2157	38.6437
TE8	CTRP2	1.4877	5.1703	1.2281	28.5423
KYSE-510	GDSC1	-5.9822	-3.9448	-5.9823	98.7081
KYSE-150	GDSC1	-4.9892	3.1932	-5.6022	77.4962
TE-8	GDSC1	-4.6408	0.6127	-4.7663	83.8159
TE-10	GDSC1	-3.8974	0.9184	-4.0136	81.0973
TE-11	GDSC1	-3.4735	0.5292	-3.5328	81.0619
TE-15	GDSC1	-3.3585	-0.1782	-3.3763	83.1208
T.T	GDSC1	-3.2312	0.4802	-3.2773	80.3078
TE-1	GDSC1	-3.1807	1.9645	-3.3893	75.4773
KYSE-270	GDSC1	-3.1608	0.346	-3.1963	80.4682
TE-5	GDSC1	-2.7696	1.2075	-2.8536	75.8757
KYSE-180	GDSC1	-2.521	1.2047	-2.5919	74.5576
KYSE-70	GDSC1	-2.085	3.1154	-2.4218	67.3467
COLO 680N	GDSC1	-1.7845	3.122	-2.0966	65.5214
OE19	GDSC1	-1.6727	2.7047	-1.8913	65.5702
TE-9	GDSC1	-1.5199	3.6663	-1.9363	62.8686
OE33	GDSC1	-1.4575	3.1099	-1.7387	63.3322
OE21	GDSC1	-1.4489	2.6662	-1.6426	64.0152
KYSE-140	GDSC1	-1.2647	3.1401	-1.5357	61.8571
KYSE-450	GDSC1	-0.9901	1.6745	-1.0291	61.4054
KYSE-410	GDSC1	-0.9269	3.5022	-1.2495	58.72
TE-11	CTRP2	-0.6347	2.8093	-0.6908	41.9376
KYSE-520	GDSC1	-0.6257	4.8825	-1.3141	55.169
KYSE-510	CTRP2	-0.5772	2.5834	-0.6148	41.5103
TE-6	GDSC1	-0.2249	2.2324	-0.275	52.6576
TE-4	CTRP2	0.0063	2.5797	-0.0126	37.5826
TE-5	CTRP2	0.0412	3.7113	-0.0716	37.6319
OE21	CTRP2	0.8343	4.1724	0.7113	32.4165
TE-6	CTRP2	0.883	3.6822	0.8237	31.8836
TE-14	CTRP2	1.3436	4.1218	1.262	28.8952
TE-9	CTRP2	1.3646	4.1355	1.2826	28.757
OE33	CTRP2	1.582	6.4884	0.9547	29.1591
KYSE-180	CTRP2	1.5984	3.269	1.591	26.9503
TE-10	CTRP2	1.7056	4.4694	1.6003	26.5683
EC-GI-10	GDSC1	2.4317	3.8966	2.3156	20.3601
COLO 680N	CTRP2	2.6269	5.9416	2.2655	21.3511
KYSE-70	CTRP2	2.7474	5.6408	0.4637	4.2652
KYSE-140	CTRP2	2.7717	3.9499	2.7666	19.1333
EC-GI-10	CTRP2	3.9446	5.6328	3.7924	11.8412
KYSE-30	CTRP2	4.0397	5.2489	3.983	10.8702
TE-1	CTRP2	4.1135	6.2239	0.9309	0.635
KYSE-450	CTRP2	4.3418	5.3821	4.2849	8.8613
KYSE-410	CTRP2	4.3452	5.5103	4.2607	8.9361
KYSE-520	CTRP2	4.4223	6.9561	3.8149	10.4149
OE19	CTRP2	4.4592	7.1018	3.7883	10.4249
KYSE-150	CTRP2	4.7664	6.3432	4.4341	7.0729

Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Pancreas Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
N2a-PK1	CTRP2	4.3829	8.5703	3.0317	13.6608
PSN1	GDSC1	-4.1951	-2.3249	-4.1952	93.7757
Capan-1	GDSC1	-3.259	0.7731	-3.3279	79.4395
CFPAC-1	GDSC1	-3.2508	1.1955	-3.3602	78.0465
Panc 10.05	GDSC1	-3.1688	2.0444	-3.3894	75.206
HuP-T4	GDSC1	-3.1147	1.5717	-3.2614	76.3494
KP-4	GDSC1	-3.0485	-0.8156	-3.0505	83.9163
PaTu 8988t	GDSC1	-2.778	2.6095	-3.0691	72.0492
Panc 03.27	GDSC1	-2.5626	1.086	-2.6252	75.1372
MIA PaCa-2	GDSC1	-2.4993	2.1336	-2.6843	71.8985
SUIT-2	GDSC1	-2.3605	1.7655	-2.4833	72.0944
KP-4	CTRP2	-1.5337	1.8286	-1.5615	47.8044
SU.86.86	GDSC1	-1.5212	9.0559	-3.8886	57.4229
HPAC	GDSC1	-1.1168	4.6843	-1.7849	58.8506
MZ-PC-1	GDSC1	-1.1159	2.48	-1.2536	61.5865
SW1990	GDSC1	-0.8894	3.3084	-1.1642	58.6165
HuP-T3	GDSC1	-0.5935	4.2729	-1.0901	55.3091
KP-2	GDSC1	-0.5513	3.3652	-0.8091	55.5545
BxPC-3	GDSC1	-0.5457	2.0979	-0.5994	56.3321
Panc 02.03	GDSC1	-0.003	3.8832	-0.3373	50.0309
KP-3	GDSC1	0.095	3.8446	-0.2203	49.0208
Panc 04.03	GDSC1	0.1048	8.0964	-1.7937	49.3442
HPAF-II	GDSC1	0.2213	4.6398	-0.3147	47.9004
KP-1N	GDSC1	0.224	3.9418	-0.1051	47.6821
Panc 03.27	CTRP2	0.6212	4.556	0.4165	34.0854
Hs 766T	GDSC1	0.9828	2.742	0.9466	37.9241
CFPAC-1	CTRP2	1.0356	5.4454	0.6675	31.8782
Panc 08.13	GDSC1	1.0641	4.5756	0.6221	38.8283
Capan-2	GDSC1	1.1946	3.3062	1.0961	35.6448
BxPC-3	CTRP2	1.3006	4.2502	1.199	29.2489
PaTu 8902	GDSC1	1.4397	6.8643	0.1166	38.1357
DAN-G	GDSC1	1.4838	2.6132	1.4762	31.5
AsPC-1	GDSC1	1.6468	4.4872	1.284	31.6374
MIA PaCa-2	CTRP2	1.7425	3.8271	1.7119	26.0687
PSN1	CTRP2	1.7755	4.8098	1.6172	26.2857
PL4	GDSC1	1.8432	5.2403	1.2208	30.8022
QGP-1	CTRP2	1.9428	6.4587	1.3562	26.6689
YAPC	GDSC1	2.08	7.841	0.3134	33.7914
SNU-410	CTRP2	2.1229	5.6178	1.8084	24.525
Panc 08.13	CTRP2	2.1507	4.5669	2.0626	23.5482
SW1990	CTRP2	2.1537	8.7648	0.6892	28.2617
Capan-1	CTRP2	2.221	7.2805	1.3617	25.8073
DAN-G	CTRP2	2.4263	5.3367	2.2113	22.1583
SUIT-2	CTRP2	2.4782	7.3174	1.622	24.1272
L3.3	CTRP2	2.5127	3.8155	1.1577	1.0992
HPAF-II	CTRP2	2.7093	4.5425	2.6612	19.6937
HuP-T4	CTRP2	2.9262	6.2952	0.2708	4.9757
SNU-213	CTRP2	3.1315	4.2937	3.1224	16.7518
HuP-T3	CTRP2	3.2878	5.7252	3.05	16.5149
KP-3	CTRP2	3.4125	5.9445	3.1204	15.8847
PaTu 8988s	CTRP2	3.4741	7.6047	2.5548	17.8575
Panc 04.03	CTRP2	3.5856	5.9412	3.31	14.6751
PANC-1	CTRP2	3.6233	9.7061	1.7547	20.5295
YAPC	CTRP2	3.7161	5.4484	1.0582	0.4919
TCC-Pan2	CTRP2	3.7439	5.5017	1.0497	0.5009
AsPC-1	CTRP2	3.7569	6.947	3.1251	14.8873
PaTu 8902	CTRP2; CTRP1	3.846	7.3784	3.0356	14.9719
Capan-2	CTRP2	4.0295	5.9655	3.7848	11.6153
Panc 02.03	CTRP2	4.176	7.218	3.4473	12.5096
HPAC	CTRP2	4.1819	5.6849	1.1499	0.1477
Hs 766T	CTRP2	4.5294	6.5492	4.1002	9.0109
Panc 05.04	CTRP2	4.5929	11.1938	-0.9641	8.3927
PK-59	CTRP2	4.6675	6.4666	1.0547	0.1803
PaTu 8988t	CTRP2	4.7618	6.4403	4.3884	7.2639
PK-45H	CTRP2	4.9029	8.8092	3.408	10.9188
KP-2	CTRP2	5.2553	5.8281	5.1584	2.9385
Panc 10.05	CTRP2	8.141	9.8494	5.0894	0.2044

Cancer Drug Sensitivity Data Curated from 105 Cell Line(s) in Skin Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SH4	CTRP2	1.0526	5.515	0.6678	31.82
HT-144	GDSC1	-4.9148	0.8868	-5.0894	83.4564
IST-MEL1	GDSC1	-4.5308	1.091	-4.707	82.0973
Mel Ho	GDSC1	-4.2936	-0.1184	-4.3413	85.6001
A-431	GDSC1	-4.2401	-0.3466	-4.2737	86.3074
Mel JuSo	GDSC1	-4.1877	0.0076	-4.2394	84.9264
COLO 679	GDSC1	-4.1714	3.786	-4.8602	74.1893
A2058	GDSC1	-3.7365	1.5656	-3.9245	78.5985
WM793	GDSC1	-3.5613	1.7817	-3.7692	77.3923
A101D	GDSC1	-3.5018	2.0508	-3.7489	76.42
WM278	GDSC1	-3.3555	1.2005	-3.4716	78.4303
IGR-37	GDSC1	-3.3102	-1.0134	-3.3121	85.945
COLO 800	GDSC1	-3.1645	0.8545	-3.2358	78.7892
Hs 944.T	CTRP2	-2.9781	1.1418	-3.0155	57.1068
G-361	GDSC1	-2.8578	0.8051	-2.9114	77.5553
CHL-1	GDSC1	-2.8071	0.7665	-2.8558	77.4218
RPMI-7951	GDSC1	-2.5034	0.2775	-2.5181	77.1549
A-388	GDSC1	-2.4015	2.6286	-2.6652	70.1599
G-mel	GDSC1	-2.1964	0.9146	-2.2316	73.3107
IGR-1	GDSC1	-2.194	1.2637	-2.2543	72.3831
WM1552C	GDSC1	-2.1379	2.4614	-2.3498	69.0763
HMV-II	GDSC1	-2.0381	1.9744	-2.1673	69.591
A-375	GDSC1	-1.9339	0.5572	-1.9459	72.1252
SH-4	GDSC1	-1.8589	3.3444	-2.2276	65.5669
RPMI-7951	CTRP2	-1.8121	1.7835	-1.8461	49.6322
MZ-MEL-7	GDSC1	-1.806	1.489	-1.8671	69.057
Hs 940.T	GDSC1	-1.5723	2.8989	-1.8199	64.5099
LB373-MEL-D	GDSC1	-1.552	2.8417	-1.7867	64.4677
MZ-MEL-2	GDSC1	-1.5432	2.0423	-1.6489	65.8736
LOX-IMVI	GDSC1	-1.4592	1.5397	-1.5083	66.0853
451Lu	GDSC1	-1.435	1.5633	-1.4849	65.8296
IPC-298	GDSC1	-1.3305	1.9887	-1.4167	64.1994
IGR-37	CTRP2	-1.1376	1.3929	-1.144	45.1508
WM266-4	CTRP2	-1.022	4.2481	-1.3028	44.846
SK-MEL-30	GDSC1	-1.0041	2.4788	-1.1336	60.5892
CP66-MEL	GDSC1	-0.998	0.6338	-0.9998	62.3244
LB2518-MEL	GDSC1	-0.9219	2.7708	-1.0927	59.4975
WM115	CTRP2	-0.8991	4.5486	-1.2302	44.156
RVH-421	GDSC1	-0.7795	2.9459	-0.9706	58.0163
WM35	GDSC1	-0.7335	1.9884	-0.7866	58.4333
GAK	GDSC1	-0.6969	1.8624	-0.7374	58.1366
SK-MEL-3	GDSC1	-0.6116	2.791	-0.7617	56.5488
SK-MEL-5	GDSC1	-0.5131	1.5428	-0.528	56.2288
WT2-iPS	CTRP2	-0.4503	3.5815	-0.5783	40.9008
DJM-1	GDSC1	-0.4111	4.08	-0.8361	53.8611
MMAc-SF	GDSC1	-0.3145	2.8411	-0.4503	53.4708
Hs 938.T	GDSC1	-0.2231	2.8683	-0.3564	52.4803
CP50-MEL-B	GDSC1	-0.0967	1.8727	-0.1151	51.181
Mel Ho	CTRP2	-0.0593	2.346	-0.0712	37.9966
UACC-62	GDSC1	0.2324	3.2222	0.0716	47.3877
COLO 800	CTRP2	0.3235	5.221	-0.0527	36.526
WT2-iPS	GDSC1	0.425	3.8537	0.1374	45.4552
M14	GDSC1	0.4721	3.2317	0.3291	44.5779
UACC-257	GDSC1	0.512	3.6289	0.288	44.3335
SK-MEL-24	GDSC1	0.5222	7.6121	-1.1531	46.4088
Malme-3M	CTRP2	0.5472	3.4099	0.4961	34.0892
COLO 792	GDSC1	0.6863	2.7815	0.629	41.6981
VMRC-MELG	GDSC1	0.8016	4.4558	0.3751	41.6884
COLO 829	GDSC1	0.8707	4.8737	0.3119	41.3558
SK-MEL-1	GDSC1	0.935	2.5856	0.91	38.457
SK-MEL-1	CTRP2	1.0162	3.9753	0.9321	31.0806
WM88	CTRP2	1.1201	4.313	0.9963	30.5227
Hs 294T	CTRP2	1.1858	5.2612	0.8776	30.6983
COLO 792	CTRP2	1.2981	3.8898	1.2403	29.118
LOX-IMVI	CTRP2	1.3043	5.6459	0.9074	30.2113
SK-MEL-24	CTRP2	1.5078	6.8672	0.7453	30.0774
WM115	GDSC1	1.5488	11.6954	-2.0422	42.1643
CJM [Human melanoma]	CTRP2	1.7352	3.7129	1.7121	26.0922
COLO 829	CTRP2	1.7517	5.854	1.337	27.3297
A-375	CTRP2	1.769	3.2755	1.7642	25.8058
SK-MEL-2	GDSC1	1.8292	3.8518	1.6697	28.1546
IGR-1	CTRP2	1.8464	4.9254	1.6713	25.8725
HMCB	CTRP2	1.9976	3.4554	1.9921	24.2869
Mel JuSo	CTRP2	2.0843	4.2038	2.0373	23.8496
IGR-39	CTRP2	2.3614	5.9826	1.9636	23.2417
SK-MEL-5	CTRP2	2.5149	7.594	-0.6488	10.8001
HT-144	CTRP2	2.5723	4.6458	2.5021	20.6814
SK-MEL-28	CTRP2	2.7903	3.638	1.3554	0.17
SK-MEL-3	CTRP2	2.8392	5.0773	2.717	19.0857
MDA-MB-435S	CTRP2	2.9268	4.6994	0.9958	1.3416
MeWo	GDSC1	2.968	4.2677	2.7908	14.09
K029AX	CTRP2	3.0671	5.5223	2.864	17.8565
RVH-421	CTRP2	3.0828	4.5907	3.0506	17.1541
SK-MEL-28	GDSC1	3.0908	4.5091	2.8338	13.1299
WM983B	CTRP2	3.2685	4.7998	3.2238	15.9609
A2058	CTRP2	3.2804	5.8712	2.999	16.7226
MeWo	CTRP2	3.2868	5.3456	3.1464	16.1723
COLO 783	GDSC1	3.3169	5.7904	2.4869	14.6402
UACC-62	CTRP2	3.3231	5.3984	3.1737	15.9634
G-361	CTRP2	3.3808	10.3421	-1.3655	12.576
SK-MEL-31	CTRP2	3.3829	4.6341	1.2245	0.2337
IPC-298	CTRP2	3.4098	4.6961	1.2126	0.2493
UACC-257	CTRP2	3.4439	6.9447	2.7949	17.0171
A101D	CTRP2	3.5495	7.2769	2.7714	16.8177
WM1799	CTRP2	3.553	7.7876	-0.03	5.4767
SK-MEL-30	CTRP2	3.6504	5.1693	1.1347	0.33
Hs 895.T	CTRP2	4.6458	7.3587	3.8591	9.6708
WM793	CTRP2	5.1479	12.7723	-1.3518	9.2844
Hs 852.T	CTRP2; CTRP1	5.3469	6.1443	5.1153	2.84
Hs 839.T	CTRP2	5.5745	8.4186	4.1983	6.2055
Hs 688(A).T	CTRP2	5.6893	6.8359	5.0853	2.2595
Hs 934.T	CTRP2	5.8641	9.0674	4.112	6.02
Hs 936.T	CTRP2	6.695	15.6312	-1.7339	8.644
Hs 940.T	CTRP2	7.505	9.5341	4.9442	0.769
EquiPSC Line K2	GDSC1	-0.5871	2.5541	-0.6983	56.4762

Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Aero Dig Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HCE-4	GDSC1	-3.1739	-0.8947	-3.176	84.8605
TE-12	GDSC1	-2.7538	1.9181	-2.9243	73.75
KYSE-50	GDSC1	-0.6738	2.6446	-0.8047	57.279
KYSE-220	GDSC1	-0.4113	2.4299	-0.4939	54.6883

Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Ascites Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
COLO 684	GDSC1	-0.4821	3.8683	-0.8561	54.6058
COLO 684	CTRP2	0.4712	6.9653	-0.4103	36.8895

Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Autonomic Ganglia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
IMR-32	CTRP2	-6.3158	-5.2638	-6.3158	79.5948
SK-N-SH	GDSC1	-5.4161	0.7202	-5.6016	84.7218
CHP-212	CTRP2	-5.1623	2.3831	-5.4456	67.0162
CHP-212	GDSC1	-5.0564	-0.4082	-5.1142	87.8206
IMR-5	GDSC1	-4.7195	-2.5134	-4.7198	95.0108
SK-N-MC-IXC	GDSC1	-4.2686	-2.7378	-4.2686	95.4818
CHP-126	GDSC1	-3.7333	0.6239	-3.812	81.5921
MHH-NB-11	GDSC1	-3.5674	0.0838	-3.602	82.9403
MHH-NB-11	CTRP2	-3.5073	-1.4109	-3.5074	60.8943
SJNB-10	GDSC1	-3.3266	2.1183	-3.5718	75.6056
CHP-126	CTRP2	-3.1002	0.4107	-3.1136	58.0358
NB1	GDSC1	-2.6338	0.7922	-2.6775	76.4129
NH-12	GDSC1	-2.6236	-0.2916	-2.6277	79.6143
SiMa	CTRP2	-2.4287	0.874	-2.4426	53.6773
NB69	GDSC1	-2.4034	0.9431	-2.4482	74.6036
SiMa	GDSC1	-1.9625	1.1742	-2.0057	70.9652
LA-N-6	GDSC1	-1.8412	4.9982	-2.6728	62.7872
NB(TU)1	GDSC1	-1.5346	4.6436	-2.2273	61.5497
SJNB-5	GDSC1	-1.098	3.6341	-1.4681	59.9177
SJNB-13	GDSC1	-0.9593	3.4607	-1.2751	59.0306
SJNB-14	GDSC1	-0.834	3.0333	-1.0465	58.4234
Kelly	GDSC1	-0.7284	3.1664	-0.9589	57.3435
KP-N-YS	GDSC1	-0.68	3.1059	-0.894	56.9513
GOTO	GDSC1	-0.6381	3.4131	-0.9144	56.3174
SK-N-BE(2)	CTRP2	-0.478	11.4722	-3.198	44.4813
SK-N-SH	CTRP2	-0.434	5.3738	-0.9174	41.5484
NH-6	CTRP2	-0.3564	3.0988	-0.4242	40.1304
NB1	CTRP2	-0.2137	3.5677	-0.3246	39.3057
KP-N-YN	CTRP2	-0.1258	8.519	-1.6187	41.4578
SJNB-12	GDSC1	0.0811	3.8944	-0.2484	49.1699
GI-ME-N	GDSC1	0.2151	8.0869	-1.6761	48.6379
Kelly	CTRP2	0.296	5.0087	-0.032	36.5713
SK-N-AS	GDSC1	0.5629	3.6144	0.3468	43.7296
SJNB-7	GDSC1	0.9665	6.7557	-0.3248	42.3127
SK-N-BE(2)-M17	GDSC1	0.9671	4.8125	0.4374	40.2272
SK-N-DZ	GDSC1	0.9857	6.7264	-0.2923	42.1158
SJNB-6	GDSC1	1.016	4.2742	0.6646	39.0069
TGW	GDSC1	1.4445	4.1449	1.1702	33.5718
KP-N-YN	GDSC1	1.7965	4.4049	1.4736	29.587
KP-N-SI9s	CTRP2	1.8704	6.2288	1.3524	26.9059
SK-N-AS	CTRP2	1.9394	4.3751	1.8636	24.9124
SK-N-DZ	CTRP2	2.0058	6.6078	1.374	26.4136
SK-N-FI	GDSC1	3.0944	4.2751	2.9249	12.4628

Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuCC-T1	GDSC1	-0.4493	4.2437	-0.9244	54.1131
SNU-1196	CTRP2	-0.4248	5.6989	-0.9942	41.6512
SNU-478	CTRP2	0.7592	3.3627	0.7214	32.6359
SNU-308	CTRP2	1.2071	3.022	1.1994	29.5555
HuH-28	CTRP2	1.3664	5.0152	1.1312	29.263
SNU-1079	CTRP2	1.9207	4.1143	1.8739	24.9379
SNU-869	CTRP2	2.1395	5.8087	1.7732	24.5987
HuCC-T1	CTRP2	2.2458	6.4472	1.6887	24.576

Cancer Drug Sensitivity Data Curated from 120 Cell Line(s) in Breast Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MCF-7	GDSC1	-4.9934	-1.6093	-5.0023	91.9357
CAL-51	GDSC1	-4.5883	-1.9056	-4.5905	92.6729
CAL-148	GDSC1	-4.468	1.4546	-4.6914	80.8688
DU4475	GDSC1	-4.2673	-1.3638	-4.2724	90.1683
EFM-192A	GDSC1	-4.1647	0.8386	-4.2876	82.0594
CAL-85-1	GDSC1	-4.0103	1.8453	-4.2619	78.5835
DU4475	CTRP2	-3.8441	1.2579	-3.9208	62.0444
CAL-148	CTRP2	-3.608	0.4321	-3.6318	61.1384
MRK-nu-1	GDSC1	-3.2769	2.4077	-3.5703	74.6356
OCUB-M	GDSC1	-3.204	-0.2246	-3.2173	82.6398
HCC1806	GDSC1	-2.9773	1.3978	-3.0937	76.2815
MDA-MB-468	GDSC1	-1.6305	1.6153	-1.6944	67.4015
BT-20	GDSC1	-1.5604	0.6715	-1.5689	68.4578
HCC1599	GDSC1	-1.4959	-0.1753	-1.4961	68.5843
UACC-893	GDSC1	-1.1123	0.7259	-1.1161	63.6012
CAMA-1	GDSC1	-1.0041	2.1367	-1.0879	61.0108
ZR-75-30	GDSC1	-0.9722	7.2471	-2.5615	55.9163
CAL-51	CTRP2	-0.8976	3.1824	-1.0041	43.77
HCC1937	GDSC1	-0.8646	3.5797	-1.2002	58.1262
AU565	GDSC1	-0.8461	2.1936	-0.927	59.4048
HCC38	GDSC1	-0.8081	3.1199	-1.0358	58.1049
HCC1500	GDSC1	-0.8022	1.8655	-0.8478	59.2627
HCC2218	GDSC1	-0.7909	2.5675	-0.9184	58.4917
BT-549	GDSC1	-0.7195	2.7049	-0.8635	57.6746
HCC1569	GDSC1	-0.6959	2.2644	-0.776	57.8161
MDA-MB-415	GDSC1	-0.4476	1.2654	-0.4527	55.5251
MDA-MB-361	GDSC1	-0.4081	3.497	-0.6832	54.1227
MDA-MB-157	CTRP2	-0.3561	12.7224	-3.6183	44.396
HCC2157	GDSC1	-0.3329	2.7404	-0.4538	53.7063
HCC70	GDSC1	-0.2517	1.6298	-0.2635	53.0865
JIMT-1	GDSC1	-0.2067	3.9847	-0.5867	52.0177
HCC1395	GDSC1	-0.1108	1.3497	-0.1135	51.378
MDA-MB-330	GDSC1	-0.0761	1.7873	-0.0899	50.9345
MDA-MB-453	GDSC1	-0.0084	3.3237	-0.2101	50.0913
MDA-MB-468	CTRP2	0.2249	3.1481	0.1803	36.2101
HCC38	CTRP2	0.3322	4.8941	0.0332	36.2559
SK-BR-3	CTRP2	0.4259	4.3033	0.2514	35.2791
COLO 824	GDSC1	0.4606	3.1512	0.3315	44.675
HCC1806	CTRP2	0.5344	4.1899	0.3869	34.4804
Evsa-T	GDSC1	0.6199	2.3734	0.5971	42.3643
HCC1954	GDSC1	0.7115	3.42	0.5512	41.8071
MDA-MB-436	GDSC1	0.8148	4.403	0.406	41.4867
MDA-MB-157	GDSC1	0.943	3.608	0.7621	39.1302
EFM-19	GDSC1	0.9781	5.099	0.348	40.4469
HCC1500	CTRP2	1.1354	3.7282	1.0848	30.1763
HCC1395	CTRP2	1.3042	2.9087	1.3003	28.8965
HCC202	GDSC1	1.3476	5.413	0.626	36.8512
EFM-192A	CTRP2	1.3777	6.8271	0.6186	30.899
MDA-MB-231	GDSC1	1.503	5.5983	0.7179	35.4467
HCC1187	GDSC1	1.5712	3.0241	1.5385	30.5653
HCC1428	GDSC1	1.6716	3.6714	1.5405	29.9316
HDQ-P1	GDSC1	1.7191	5.0846	1.1488	31.9535
CAL-85-1	CTRP2	1.7506	6.8615	1.0097	28.4446
MFM-223	GDSC1	1.8005	3.0336	1.7786	27.6316
MDA-MB-175-VII	GDSC1	1.8236	3.4966	1.7409	27.7317
HCC1419	GDSC1	1.8631	3.1402	1.8343	26.8932
BT-474	GDSC1	2.0617	6.0657	1.1051	30.179
HCC2218	CTRP2	2.0896	5.4908	1.8057	24.638
HMC-1-8	CTRP2	2.1133	4.4523	2.0387	23.7508
HCC1419	CTRP2	2.1325	6.1295	1.6689	24.9898
CAL-120	GDSC1	2.2063	6.7075	0.9647	30.1304
HCC1954	CTRP2	2.2791	3.8409	2.2667	22.4363
BT-20	CTRP2	2.3183	3.5835	2.3148	22.1457
Hs 578T	GDSC1	2.6217	5.6065	1.881	22.3525
MCF-7	CTRP2	2.7218	4.7269	2.6504	19.6904
T-47D	GDSC1	2.7222	5.1833	2.1687	19.8204
CAMA-1	CTRP2	2.7532	4.8557	2.6642	19.5426
BT-474	CTRP2	2.8629	7.2463	2.0591	21.4231
Hs 578T	CTRP2	2.9296	5.093	2.8119	18.4684
UACC-812	GDSC1	3.0251	7.7664	1.2533	24.4511
HCC1428	CTRP2	3.0659	5.568	2.8508	17.9077
BT-483	GDSC1	3.3061	8.264	1.2653	23.1333
HCC1143	CTRP2	3.5331	5.7038	0.8779	1.2225
ZR-75-1	CTRP2	3.5902	4.8943	1.21	0.1954
MDA-MB-361	CTRP2	3.643	6.1942	3.2886	14.5861
JIMT-1	CTRP2	3.8239	5.4135	3.7155	12.4872
HCC1937	CTRP2	3.8749	5.6967	3.6986	12.3916
BT-549	CTRP2	4.0968	5.5924	3.9693	10.7411
HCC202	CTRP2	4.2575	6.9335	3.6545	11.4796
T-47D	CTRP2	5.1419	10.9177	2.5778	13.8075
Hs 578Bst	CTRP2	5.1712	12.1263	2.0008	16.0234
MDA-MB-231	CTRP2	5.2395	6.8561	4.6748	4.9226
MDA-MB-453	CTRP2	5.3315	6.2135	5.07	3.0884
ZR-75-30	CTRP2	5.367	8.3493	4.054	7.2301
KPL-1	CTRP2	5.8209	11.8475	2.6883	13.7816
MDA-MB-415	CTRP2	7.5679	9.3378	5.0493	0.4708
AU565	CTRP2	8.7332	10.7147	5.0042	0.1921
BT 239	CTRP2	-2.3203	1.4347	-2.3524	52.9333
BT 145	CTRP2	-2.0429	1.7217	-2.0811	51.1322
BT 271	CTRP2	-1.5052	2.3031	-1.5604	47.6454
BT164	CTRP2	-1.1956	2.4878	-1.2513	45.6241
BT 112	CTRP2	-0.612	4.0035	-0.8156	42.1178
BT 504	CTRP2	-0.4167	5.1664	-0.8462	41.3376
BT 139	CTRP2	0.5961	5.7182	0.1146	35.0678
BT 286	CTRP2	0.8737	11.7164	-1.918	38.4622
BT 428	CTRP2	0.9317	9.6267	-0.9479	36.4775
BT 172	CTRP2	1.2199	7.8823	0.0622	33.0599
BT 228	CTRP2	1.9811	6.5167	1.3782	26.4747
BT 179	CTRP2	2.304	3.7581	2.2955	22.2577
BT 440	CTRP2	2.3394	8.7738	0.878	27.1043
BT147	CTRP2	2.4786	10.9998	0.0216	29.3324
BT 187	CTRP2	2.4883	7.3959	1.6022	24.1688
BT 330	CTRP2	2.6475	10.1939	0.5609	27.247
BT 224	CTRP2	3.0086	5.6386	2.7693	18.3754
BT 131	CTRP2	3.7343	13.4613	0.0485	25.9731
BT 159	CTRP2	4.0842	8.1326	2.9429	14.7493
BT 231	CTRP2	4.3832	7.6958	3.4422	12.0022
BT 416	CTRP2	5.0616	11.4786	2.2281	15.3699
BT 216	CTRP2	5.5491	14.3446	1.2143	18.1526
BT 245	CTRP2	5.7292	13.432	1.8206	15.5797
BT 333	CTRP2	5.7432	6.8183	5.1372	1.9436
BT 482	CTRP2	5.8449	7.125	5.0635	2.076
BT 422	CTRP2	5.8577	7.0919	5.0894	1.9468
BT 444	CTRP2	5.8821	7.5027	4.9047	2.6737
BT 498	CTRP2	5.9712	7.2527	5.0932	1.7523
BT 359	CTRP2	6.492	8.541	4.8264	2.1006
BT 320	CTRP2	6.9159	8.0173	5.277	0.2538
BT 328	CTRP2	7.1216	16.101	1.5899	13.9028
BT 232	CTRP2	7.716	21.9975	-0.8768	20.6279
BT 340	CTRP2	9.7673	23.4132	-0.0835	15.3149

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
YD-38	CTRP2	2.7621	4.4327	2.7285	19.2932

Cancer Drug Sensitivity Data Curated from 98 Cell Line(s) in Central Nervous System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
H4	GDSC1	-5.3218	-0.9415	-5.3586	89.8745
SF295	GDSC1	-4.9194	-2.0127	-4.9225	93.325
SK-MG-1	GDSC1	-4.4697	1.6174	-4.7187	80.399
SW1783	GDSC1	-3.9502	-0.8328	-3.9606	87.4582
KALS-1	GDSC1	-3.8959	5.6886	-5.131	69.8143
GI-1	GDSC1	-3.8313	0.0684	-3.8738	83.8103
8-MG-BA	GDSC1	-3.3573	0.4017	-3.4031	81.0732
Daoy	GDSC1	-3.3563	0.0094	-3.3812	82.4417
SF539	GDSC1	-2.9545	0.149	-2.9749	80.1732
D283 Med	CTRP2	-2.8387	-0.2335	-2.8406	56.4321
M059J	GDSC1	-2.752	2.5225	-3.0243	72.1481
U-251MG	GDSC1	-2.731	0.5033	-2.7611	77.8452
SF268	GDSC1	-2.3908	1.2291	-2.4575	73.7253
NMC-G1	GDSC1	-2.3407	4.6347	-3.103	65.8331
LN-18	GDSC1	-2.1732	2.0626	-2.3239	70.2307
KS-1 [Human Krukenberg tumour]	GDSC1	-2.0628	3.1516	-2.4057	67.1457
D283 Med	GDSC1	-2.0579	-0.0141	-2.0607	74.3826
AM-38	GDSC1	-1.9713	1.5537	-2.0471	70.1327
SNB-75	GDSC1	-1.7295	4.7363	-2.4683	62.5472
Hs 683	GDSC1	-1.7093	2.6402	-1.9191	65.9481
Onda 10	GDSC1	-1.5371	3.2902	-1.8648	63.5904
ONS-76	GDSC1	-1.4724	3.0311	-1.7383	63.5697
GaMG	GDSC1	-1.443	5.7775	-2.5055	59.6874
D-566MG	GDSC1	-1.3829	1.4325	-1.4208	65.5714
YKG-1	GDSC1	-1.3749	4.248	-1.9353	61.0792
MOG-G-UVW	GDSC1	-1.2728	2.3884	-1.4079	63.0675
D-263MG	GDSC1	-1.1436	5.7172	-2.1609	58.0192
T98G	GDSC1	-1.047	2.1894	-1.1397	61.3499
A-172	GDSC1	-0.8824	4.1437	-1.3683	57.712
LN-229	GDSC1	-0.8158	1.9446	-0.8691	59.3357
DBTRG-05MG	GDSC1	-0.7292	4.2303	-1.2258	56.4386
D-542MG	GDSC1	-0.6399	3.8056	-1.0119	56.0316
GB-1	GDSC1	-0.516	2.3911	-0.6004	55.8381
KNS-42	GDSC1	-0.307	9.4195	-2.7992	51.6239
Becker	GDSC1	-0.2288	4.0977	-0.642	52.1955
SNU-626	CTRP2	-0.1492	4.1109	-0.3354	39.0814
SW1783	CTRP2	0.3394	9.1898	-1.3891	39.3708
U-87MG ATCC	GDSC1	0.3846	4.4599	-0.0802	46.195
D-423MG	GDSC1	0.4365	2.8003	0.3608	44.8094
LNZTA3WT4	GDSC1	0.4556	3.2588	0.3061	44.7883
SF126	GDSC1	0.575	3.7137	0.3363	43.6551
MOG-G-CCM	GDSC1	0.6147	4.0761	0.2844	43.4633
KNS-81-FD	GDSC1	0.7437	6.0551	-0.2684	43.7136
Hs 683	CTRP2	0.8034	5.6108	0.3703	33.5914
LN-405	GDSC1	1.0607	3.849	0.8322	37.9426
SF539	CTRP2	1.0709	5.1753	0.7729	31.4215
SNU-466	CTRP2	1.0969	3.3309	1.074	30.3396
Onda 11	GDSC1	1.2443	8.0318	-0.605	41.2157
U-251MG	CTRP2	1.2875	6.0895	0.7609	30.7427
LN-18	CTRP2	1.2942	3.5192	1.267	29.0412
42-MG-BA	GDSC1	1.4138	5.6392	0.6072	36.4953
SF268	CTRP2	1.457	5.8818	1.0075	29.3843
U-118MG	GDSC1	1.4629	5.591	0.6783	35.877
Daoy	CTRP2	1.5668	4.7841	1.3962	27.7145
T98G	CTRP2	1.6291	2.8864	1.6281	26.7244
8-MG-BA	CTRP2	1.7658	3.9285	1.7282	25.9376
CAS-1	GDSC1	1.8172	4.8443	1.3437	30.2463
CCF-STTG1	CTRP2	1.8811	4.1284	1.8307	25.2134
AM-38	CTRP2	1.8933	4.4271	1.8074	25.2534
SF295	CTRP2	1.9768	5.0105	1.7953	25.0282
SW1088	GDSC1	1.9913	5.9494	1.0829	30.6997
LN-229	CTRP2	2.0659	4.244	2.0136	23.9903
GOS-3	CTRP2	2.0744	8.3851	0.7658	28.2529
ONS-76	CTRP2	2.184	4.3649	2.125	23.2267
GB-1	CTRP2	2.2481	5.6962	1.9235	23.7307
PFSK-1	GDSC1	2.2891	6.6299	1.0831	29.0536
YH-13	GDSC1	2.4754	5.1203	1.9373	22.7238
KNS-60	CTRP2	2.6402	3.8141	2.6363	20.0045
A-172	CTRP2	2.7056	7.4751	1.8015	22.821
42-MG-BA	CTRP2	2.7786	10.205	0.687	26.4831
GaMG	CTRP2; CTRP1	2.7954	6.0318	2.4203	20.2604
CAS-1	CTRP2	3.021	8.9229	1.5128	26.3494
KINGS-1	GDSC1	3.0975	5.3664	2.4708	15.7699
SNU-201	CTRP2	3.1395	7.8421	2.1061	20.4775
SNB-75	CTRP2	3.2003	7.2779	2.4037	19.1828
U-118MG	CTRP2	3.2152	8.3079	1.9834	20.7348
KNS-81	CTRP2	3.2401	7.5296	2.3424	19.3062
D-392MG	GDSC1	3.4555	5.9923	2.5203	13.7817
NMC-G1	CTRP2	3.4821	7.3771	2.6592	17.4334
Becker	CTRP2	3.588	8.7988	2.1412	19.1547
SF126	CTRP2	3.6069	5.9398	3.3336	14.5253
SNU-738	CTRP2	3.6207	5.1157	3.5545	13.6913
DK-MG	GDSC1	3.6358	5.2906	3.0307	9.0738
YH-13	CTRP2	3.7896	9.6557	1.9409	19.4103
SNU-489	CTRP2	3.8453	5.7377	3.6546	12.6405
D-502MG	GDSC1	3.8611	5.1086	3.3261	5.8405
KALS-1	CTRP2	3.8885	5.6827	3.7175	12.282
SNU-1105	CTRP2	3.934	4.7829	3.9249	11.4106
DK-MG	CTRP2	4.0097	6.7144	3.486	12.8033
KG-1-C	CTRP2	4.0687	7.3106	3.2965	13.3852
U-87MG ATCC	CTRP2	4.3348	8.0166	3.2455	12.9138
DBTRG-05MG	CTRP2	4.6443	6.1359	4.388	7.5855
TM-31	CTRP2	4.8076	7.578	3.9146	9.053
GMS-10	CTRP2	4.8246	7.5711	3.9344	8.9318
YKG-1	CTRP2	4.9881	7.0424	4.3439	6.8704
KNS-42	CTRP2	5.0186	10.5212	2.6663	13.7109
M059K	CTRP2	6.1564	13.2513	2.2584	13.0845
SW1088	CTRP2	6.5518	16.1028	-2.0306	10.0345

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
ETK-1	GDSC1	-3.3076	1.1324	-3.4134	78.4651
TGBC24TKB	GDSC1	-0.5877	1.4759	-0.6018	57.1287
TGBC1TKB	GDSC1	0.2315	3.1885	0.0771	47.3887

Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Endometrium Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JHUEM-2	CTRP2	-6.5773	0.0534	-6.6807	75.0021
ESS-1	GDSC1	-3.6146	-0.6509	-3.6241	85.7925
MFE-296	GDSC1	-1.7636	3.0302	-2.0542	65.5602
AN3-CA	GDSC1	-1.4377	2.6454	-1.6269	63.9659
MFE-319	GDSC1	-0.6375	2.3896	-0.7294	57.1146
JHUEM-1	CTRP2	-0.0721	3.3934	-0.154	38.2912
ESS-1	CTRP2	0.1989	3.793	0.0857	36.5924
RL95-2	CTRP2	1.1397	3.6388	1.0971	30.1207
HEC-265	CTRP2	1.3201	2.1655	1.3201	28.7777
JHUEM-7	CTRP2	1.4871	5.1634	1.2291	28.541
KLE	GDSC1	1.5629	5.8801	0.6659	35.2978
EN	GDSC1	1.7448	5.5698	0.9846	32.6678
HEC-6	CTRP2	1.8722	3.1858	1.87	25.1104
KLE	CTRP2; CTRP1	1.9529	7.0181	1.1717	27.2729
HEC-1-B	CTRP2	2.269	4.1476	2.2367	22.5706
MFE-296	CTRP2	2.5226	6.7793	1.8717	23.0937
MFE-280	GDSC1	2.677	5.8346	1.8351	22.388
HEC-1-A	CTRP2	2.8743	5.4859	2.663	19.1675
HEC-108	CTRP2; CTRP1	3.0072	3.6591	3.0072	17.5489
HEC-251	CTRP2	3.0264	4.4293	3.0055	17.4912
JHUEM-3	CTRP2	3.1262	6.633	2.5744	18.7467
HEC-59	CTRP2; CTRP1	3.1332	5.0779	3.0351	17.0458
AN3-CA	CTRP2	3.1492	6.6555	2.5908	18.6195
MFE-319	CTRP2	3.6219	5.2914	3.5225	13.7992
HEC-151	CTRP2	4.071	5.3354	1.2293	0.0749
EFE-184	CTRP2	4.2982	5.9932	1.0855	0.2176
HEC-50B	CTRP2	4.728	8.2063	3.5374	10.7842
EN	CTRP2	5.0471	5.6379	4.9942	4.1566
Ishikawa (Heraklio) 02 ER-	CTRP2; CTRP1	2.3075	4.0259	2.2859	22.2783

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Kidney Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
769-P	GDSC1	-6.6901	-0.0501	-6.861	88.0883
Caki-1	GDSC1	-5.0799	1.8156	-5.4097	81.0956
LB1047-RCC	GDSC1	-4.8522	0.4572	-4.973	84.6871
LB996-RCC	GDSC1	-4.7203	-0.8002	-4.747	88.76
HA7-RCC	GDSC1	-4.4958	0.9959	-4.6574	82.3162
786-O	GDSC1	-3.6928	-1.0818	-3.6965	87.6834
BFTC-909	GDSC1	-3.4743	1.3442	-3.6148	78.4097
LB2241-RCC	GDSC1	-3.1215	-1.6177	-3.1215	86.9271
BB65-RCC	GDSC1	-2.8595	2.6897	-3.1733	72.2135
ACHN	GDSC1	-2.8489	-0.8235	-2.85	82.7123
VMRC-RCZ	GDSC1	-2.8298	1.7454	-2.9809	74.5917
VMRC-RCW	GDSC1	-2.1733	1.9111	-2.3029	70.6027
OS-RC-2	GDSC1	-2.036	4.1341	-2.6243	65.1599
UO-31	GDSC1	-1.385	2.7312	-1.5854	63.4175
SW13	GDSC1	-0.9523	3.5938	-1.2993	58.8258
TK-10	GDSC1	-0.8734	4.4593	-1.4506	57.3508
SW156	GDSC1	-0.6195	2.9315	-0.7951	56.5189
KMRC-20	GDSC1	-0.3922	3.2067	-0.6024	54.1123
RCC10RGB	GDSC1	0.2138	5.308	-0.5508	48.1363
BFTC-909	CTRP2	0.4975	3.234	0.4581	34.3818
CAL-54	GDSC1	0.7125	4.4796	0.2706	42.703
KMRC-20	CTRP2	1.015	4.8768	0.7791	31.5881
A-704	GDSC1	1.1581	6.129	0.1383	39.8553
SN12C	GDSC1	1.5563	6.0848	0.5734	35.7327
RXF 393L	GDSC1	1.6054	6.6179	0.3948	36.1468
CAL-54	CTRP2	1.671	5.511	1.3437	27.5614
A-498	CTRP2	1.7808	2.9625	1.78	25.7138
Caki-2	CTRP2	1.9494	2.6903	1.9494	24.5893
769-P	CTRP2	1.96	4.7645	1.825	24.9787
ACHN	CTRP2	2.2265	5.6426	1.9147	23.8286
UO-31	CTRP2	2.2589	5.5229	1.982	23.4897
KMRC-1	GDSC1	2.556	4.3675	2.3104	19.6956
TUHR10TKB	CTRP2	2.6685	4.1086	2.6546	19.8496
786-O	CTRP2	2.8259	4.7155	2.7633	18.9673
KMRC-1	CTRP2	2.8716	7.2993	2.0474	21.4422
SNU-1272	CTRP2	3.1683	4.9786	3.0904	16.7419
TUHR14TKB	CTRP2	3.5884	5.1976	3.5049	13.9663
OS-RC-2	CTRP2	3.7531	7.3035	2.9729	15.4878
VMRC-RCZ	CTRP2	3.7937	6.3063	3.4116	13.6913
TUHR4TKB	CTRP2	3.8021	4.966	3.7703	12.3656
VMRC-RCW	CTRP2	4.1059	5.9192	1.0399	0.365
KMRC-2	CTRP2	4.5448	6.8147	4.0026	9.3534
Caki-1	CTRP2	4.8148	11.496	2.001	16.7858
A-498	GDSC1	6.671	23.9636	-3.8526	30.348
RCC10RGB	CTRP2	7.1829	8.8157	5.0833	0.5872

Cancer Drug Sensitivity Data Curated from 83 Cell Line(s) in Large Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
COLO205	GDSC1	-6.5061	-0.437	-6.6266	89.0547
SW620	GDSC1	-5.3034	-0.5022	-5.3645	88.4003
LS180	GDSC1	-4.8796	0.8633	-5.0489	83.4666
LS1034	GDSC1	-4.8363	3.0692	-5.406	77.4515
HT-29	GDSC1	-4.3807	0.9267	-4.5266	82.2827
SW48	CTRP2	-3.8485	0.4983	-3.8809	62.5068
SK-CO-1	CTRP2	-3.6065	0.036	-3.6189	61.2754
GP5d	GDSC1	-3.5504	0.4576	-3.6077	81.5731
T84	GDSC1	-3.0973	2.1351	-3.3276	74.6678
RKO	GDSC1	-2.8193	-0.3714	-2.8242	81.1285
HCC2998	GDSC1	-2.5481	1.791	-2.6866	73.0639
LS411N	GDSC1	-2.1964	2.1918	-2.3683	70.0578
SNU-175	CTRP2	-2.1541	0.9391	-2.1652	51.8829
SW48	GDSC1	-2.1448	-0.1276	-2.1471	75.3958
SW626	GDSC1	-1.8328	2.629	-2.0504	66.8027
SNU-C2B	GDSC1	-1.7637	3.591	-2.1833	64.5432
NCI-H747	GDSC1	-1.6066	3.4284	-1.9725	63.8246
HCT 15	GDSC1	-1.4021	2.7074	-1.5995	63.5887
LoVo	GDSC1	-1.1961	1.0856	-1.21	64.1941
CaR-1	GDSC1	-0.9621	2.8366	-1.1478	59.7782
LS513	CTRP2	-0.831	3.0636	-0.9205	43.3021
SW837	GDSC1	-0.7648	2.5795	-0.8923	58.2285
CCK-81	GDSC1	-0.2993	2.0625	-0.3379	53.5618
HT115	CTRP2	-0.1549	4.0723	-0.3351	39.103
COLO 320HSR	GDSC1	-0.0656	3.6053	-0.3357	50.6826
RCM-1 [Human ESC]	GDSC1	0.0124	2.2383	-0.0264	49.851
HCT 116	GDSC1	0.0227	3.2677	-0.1648	49.7522
LS180	CTRP2	0.044	3.962	-0.104	37.7137
LS513	GDSC1	0.052	3.2687	-0.1332	49.4295
KM12	GDSC1	0.0721	4.5778	-0.4573	49.3229
SW1417	GDSC1	0.1373	2.5795	0.0705	48.3756
CCK-81	CTRP2	0.175	7.9294	-1.0741	39.4054
NCI-H747	CTRP2	0.2151	4.0306	0.0691	36.5824
LS123	GDSC1	0.299	6.3765	-0.8677	47.6888
SNU-C1	GDSC1	0.9115	3.6473	0.7188	39.5592
MDST8	GDSC1	1.2318	4.6876	0.7667	37.0294
CW-2	CTRP2	1.2969	4.9531	1.069	29.6983
NCI-H716	GDSC1	1.4186	3.9347	1.2004	33.5705
HT-55	GDSC1	1.4821	3.1801	1.4248	31.8302
GP2d	CTRP2	1.5024	3.6395	1.4753	27.6552
T84	CTRP2	1.5096	5.3492	1.2089	28.5372
COLO 678	GDSC1	1.5667	4.1674	1.2969	32.0644
CL-11	CTRP2	1.5973	6.0154	1.1209	28.5548
SNU-C1	CTRP2	1.8485	2.6822	1.8484	25.2612
COLO 678	CTRP2	1.8634	5.3482	1.5949	26.0841
SW948	GDSC1	1.9	4.1939	1.6525	27.8429
RCM-1 [Human ESC]	CTRP2	1.9385	3.271	1.9358	24.6711
SW1417	CTRP2	1.9432	4.5411	1.8441	24.9664
SNU-81	CTRP2	1.9801	2.9942	1.9798	24.3859
SW948	CTRP2	2.0773	4.5215	1.9906	24.0317
SW1463	GDSC1	2.109	6.2863	1.0563	30.1793
NCI-H716	CTRP2	2.2505	4.6336	2.1595	22.8942
COLO205	CTRP2	2.2877	4.1754	2.2538	22.4514
HCT 15	CTRP2	2.3301	3.8118	2.3203	22.0882
C2BBe1	GDSC1	2.34	6.3344	1.2689	27.7319
HT-29	CTRP2	2.514	3.5015	2.5132	20.8341
DLD-1	CTRP2	2.6284	3.773	2.6252	20.0808
HCT 116	CTRP2	2.6778	3.5916	2.6771	19.7437
HT-55	CTRP2	2.7536	4.485	0.9964	1.5447
SNU-61	CTRP2	2.8279	4.8643	0.8704	2.0461
CL-11	GDSC1	2.8682	7.4993	1.2363	25.2798
LS1034	CTRP2	2.8815	5.9445	2.542	19.5826
CW-2	GDSC1	3.0142	4.9739	2.5609	15.5073
SNU-503	CTRP2	3.14	5.4694	2.9569	17.3004
COLO201	CTRP2	3.1693	5.5221	2.9756	17.1435
SW620	CTRP2	3.184	7.7722	-0.2607	7.3314
RKO	CTRP2	3.2033	4.5662	3.1796	16.3233
SNU-C2A	CTRP2	3.2319	5.3146	3.0936	16.5303
HT115	GDSC1	3.3045	10.1812	0.3123	28.0857
SNU-C4	CTRP2	3.3312	4.5174	3.3165	15.4417
NCI-H508	CTRP2	3.3757	4.7148	3.3469	15.1931
HCT 8	CTRP2	3.3907	4.6928	3.3648	15.0837
MDST8	CTRP2	3.4567	4.6965	1.2301	0.1982
C2BBe1	CTRP2	3.5301	6.4696	3.0685	15.736
OUMS-23	CTRP2	3.727	4.9657	3.6906	12.8809
LS411N	CTRP2	3.7788	5.009	3.7401	12.5445
LS123	CTRP2	3.8895	5.9101	0.9562	0.6882
KM12	CTRP2	4.0444	5.2002	3.9964	10.8089
SNU-407	CTRP2	4.1348	6.9126	0.6715	1.4851
LoVo	CTRP2	4.167	6.3417	0.9088	0.6685
HCC-56	CTRP2	4.5662	7.2985	3.8074	10.0773
SNU-C5	CTRP2	4.6521	6.5822	1.0094	0.2523
COLO 320	CTRP2	8.362	10.7482	4.8475	0.5686

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MO-T	GDSC1	2.3721	4.578	2.0377	22.5897

Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Liver Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JHH-7	GDSC1	-2.8152	2.9479	-3.179	71.393
Hep-G2/C3A	GDSC1	-2.299	2.0427	-2.4557	71.0262
JHH-5	CTRP2	-2.2095	5.5365	-2.8976	51.7872
JHH-4	GDSC1	-0.7984	2.3585	-0.8969	58.7689
HLE	GDSC1	-0.702	2.0169	-0.7562	58.0769
JHH-1	GDSC1	-0.6582	2.8857	-0.8285	56.9283
Hep 3B2.1-7	GDSC1	-0.623	5.4471	-1.5032	54.8103
SK-HEP-1	GDSC1	-0.4674	3.0117	-0.6455	54.9677
SNU-475	GDSC1	-0.3302	2.4495	-0.4102	53.789
SNU-398	GDSC1	-0.33	3.55	-0.6106	53.346
HLF	CTRP2	0.3079	4.809	0.0255	36.367
JHH-6	GDSC1	0.5345	3.3875	0.3659	43.9201
HuH-1	GDSC1	0.6052	2.1141	0.5955	42.4857
SNU-423	GDSC1	0.6918	5.166	0.0154	43.5065
Li-7	CTRP2	0.8316	5.271	0.489	33.1319
Huh-7	GDSC1	0.8978	5.3732	0.1606	41.5984
SNU-387	GDSC1	1.3145	7.0574	-0.0967	39.5458
SNU-449	GDSC1	1.9051	5.4207	1.2143	30.4733
JHH-1	CTRP2	1.9384	3.4847	1.9311	24.6869
SNU-475	CTRP2	1.9684	2.7388	1.9684	24.4627
HuH-1	CTRP2	2.1806	5.5352	1.8934	24.046
SNU-878	CTRP2	2.2866	5.5708	1.9997	23.3412
JHH-2	GDSC1	2.3735	4.1582	2.1794	21.6126
SNU-182	CTRP2	2.5812	3.5554	2.5803	20.3872
PLC/PRF/5	CTRP2	3.0253	5.1385	2.9066	17.8354
JHH-4	CTRP2	3.4374	5.7991	3.1918	15.5492
Hep 3B2.1-7	CTRP2	3.5811	4.859	3.5485	13.8392
Hep-G2	CTRP2	3.7132	11.2142	-1.5548	12.7944
HuH-6	CTRP2	3.8603	6.4176	0.7427	1.4535
SNU-761	CTRP2	4.1044	5.7697	3.9278	10.8683
SNU-398	CTRP2	4.4383	5.3477	4.3957	8.1693
SK-HEP-1	CTRP2	4.7966	6.4184	4.4338	6.9933
SNU-423	CTRP2	4.8282	10.5496	2.482	14.8651
JHH-2	CTRP2	4.9144	5.6667	4.8415	5.1105
SNU-387	CTRP2	5.1904	5.8946	5.0635	3.4821
JHH-6	CTRP1	5.4045	5.8067	5.3239	3.9961
SNU-449	CTRP2; CTRP1	5.4645	7.9541	4.336	5.848

Cancer Drug Sensitivity Data Curated from 308 Cell Line(s) in Lung Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H2170	GDSC1	-6.7583	-1.1033	-6.8359	91.0149
NCI-H2228	GDSC1	-6.3555	1.0788	-6.6586	84.8309
LC-2/ad	GDSC1	-6.1593	-3.7899	-6.1594	98.294
NCI-H460	GDSC1	-6.1561	-2.0536	-6.1722	93.7076
SK-LU-1	GDSC1	-6.1156	0.0006	-6.2589	87.5574
DV-90	CTRP2	-6.0108	4.4295	-6.7653	67.5265
NCI-H441	GDSC1	-5.6782	1.5195	-6.003	82.8571
NCI-H2122	GDSC1	-5.5483	-1.0041	-5.5888	90.2416
COLO 668	GDSC1	-5.5311	0.6016	-5.7089	85.2189
NCI-H209	GDSC1	-5.3398	-0.7935	-5.3846	89.3956
NCI-H1651	GDSC1	-5.215	-0.5171	-5.2717	88.3606
NCI-H3122	GDSC1	-5.0277	1.7453	-5.3409	81.1892
Lu-135	GDSC1	-5.0201	-0.8334	-5.0533	89.2312
NCI-H2342	GDSC1	-4.8767	0.2273	-4.9762	85.4676
NCI-H2110	GDSC1	-4.7381	0.7794	-4.8883	83.4707
NCI-H1781	GDSC1	-4.7371	-0.5389	-4.7762	87.8561
HOP-62	GDSC1	-4.6766	-0.1926	-4.7339	86.5588
NCI-H2804	GDSC1	-4.5596	2.9966	-5.0877	76.9861
LXF 289	GDSC1	-4.5522	0.2315	-4.6362	84.8996
SBC-5	GDSC1	-4.3516	-1.5836	-4.3549	91.1504
Lu-134-A	GDSC1	-4.2823	2.3164	-4.641	78.0109
COR-L279	CTRP2	-4.2394	0.163	-4.2681	64.8889
NCI-H748	GDSC1	-4.0924	2.2547	-4.4236	77.673
HCC44	GDSC1	-3.9579	1.1879	-4.1095	80.407
NCI-H2141	CTRP2	-3.933	4.629	-4.549	60.145
SK-MES-1	GDSC1	-3.6435	1.2948	-3.7886	79.1318
NCI-H526	GDSC1	-3.6418	-0.5881	-3.6531	85.6466
NCI-H1355	GDSC1	-3.5141	2.6326	-3.8716	74.8986
IA-LM	GDSC1	-3.452	1.2299	-3.5773	78.6879
COLO 668	CTRP2; CTRP1	-3.4469	2.1271	-3.5841	59.414
NCI-H2087	GDSC1	-3.4233	0.0526	-3.452	82.5429
NCI-H209	CTRP2	-3.4105	0.6813	-3.4391	59.8665
NCI-H1341	CTRP2	-3.3349	0.9885	-3.3755	59.3031
NCI-H1944	GDSC1	-3.2896	0.7051	-3.3544	79.7851
A-549	GDSC1	-3.1744	1.1904	-3.2789	77.7578
NCI-H1734	CTRP2	-3.1643	0.1294	-3.1727	58.496
DMS 273	GDSC1	-3.1498	2.528	-3.4558	73.8312
NCI-H1048	GDSC1	-3.144	1.8127	-3.3265	75.7637
HCC78	GDSC1	-3.1402	1.8801	-3.3327	75.5554
EBC-1	GDSC1	-3.1009	0.2871	-3.1314	80.4045
LCLC-97TM1	GDSC1	-3.0131	3.2287	-3.4576	71.5723
SBC-3	GDSC1	-3.0112	0.556	-3.0539	79.0951
NCI-H1155	CTRP2	-2.8786	-0.2056	-2.8808	56.6917
EPLC-272H	GDSC1	-2.8753	0.8195	-2.9307	77.5959
ABC-1	GDSC1	-2.8318	-0.9057	-2.8326	82.837
NCI-H727	GDSC1	-2.7928	3.5719	-3.3009	69.8908
NCI-H1437	GDSC1	-2.7896	0.5672	-2.825	77.9602
NCI-H1734	GDSC1	-2.7684	1.5565	-2.8909	74.8407
NCI-H520	GDSC1	-2.7014	1.326	-2.7937	75.1784
SW1573	GDSC1	-2.6943	1.0686	-2.7616	75.9068
NCI-H1876	GDSC1	-2.6247	1.1766	-2.6983	75.2147
NCI-H2228	CTRP2	-2.5738	3.7882	-2.8943	54.0365
NCI-H211	GDSC1	-2.526	1.5125	-2.6286	73.713
NCI-H1299	GDSC1	-2.2604	3.2885	-2.6519	67.9514
NCI-H522	GDSC1	-2.2361	1.1104	-2.286	73.066
NCI-H810	GDSC1	-2.2192	1.9892	-2.3627	70.6897
NCI-H1105	CTRP2	-2.2005	2.7426	-2.3342	52.0582
Calu-3	GDSC1	-2.1774	4.074	-2.7619	66.0042
Lu-99A	GDSC1	-2.1539	1.7104	-2.2571	70.9799
NCI-H1770	GDSC1	-2.1492	2.8079	-2.4269	68.3655
SBC-5	CTRP2	-2.0979	1.2056	-2.1152	51.5062
COR-L23	GDSC1	-2.0806	1.7342	-2.1822	70.446
NCI-H2030	GDSC1	-2.0559	1.2392	-2.1079	71.4941
NCI-H1650	GDSC1	-2.0471	2.5987	-2.2764	68.2226
Lu-99	CTRP2	-1.945	3.2207	-2.1244	50.4691
Calu-6	GDSC1	-1.9207	3.6766	-2.3761	65.3243
NCI-H211	CTRP2	-1.9007	1.6189	-1.9293	50.2103
NCI-H2170	CTRP2	-1.8801	2.9035	-2.0134	50.0727
DMS 53	CTRP2	-1.8614	1.6588	-1.8907	49.9535
NCI-H526	CTRP2	-1.8099	0.5063	-1.8117	49.6109
NCI-H358	GDSC1	-1.7786	1.4175	-1.8323	68.9982
NCI-H290	GDSC1	-1.7718	0.967	-1.7959	69.8878
NCI-H2009	GDSC1	-1.7527	3.4898	-2.1464	64.652
NCI-H2405	GDSC1	-1.6836	4.2707	-2.2787	62.9621
NCI-H1435	GDSC1	-1.6556	0.4459	-1.6608	69.739
A-427	GDSC1	-1.5748	2.0224	-1.68	66.1613
CPC-N	GDSC1	-1.5249	3.0272	-1.7944	63.9503
NCI-H23	CTRP2	-1.5214	3.4668	-1.707	47.8533
NCI-H2081	CTRP2	-1.5053	4.3459	-1.846	47.8552
HCC15	GDSC1	-1.4972	2.5186	-1.6694	64.6411
COR-L88	GDSC1	-1.4941	2.8098	-1.7179	64.1046
LB647-SCLC	GDSC1	-1.4905	2.1178	-1.6026	65.313
NCI-H1703	GDSC1	-1.4819	1.4693	-1.5265	66.409
IST-SL2	GDSC1	-1.4709	1.5003	-1.5174	66.2572
NCI-H2023	GDSC1	-1.4392	6.6742	-2.8328	58.807
NCI-H1304	GDSC1	-1.4204	3.0008	-1.6757	63.2416
NCI-H2172	GDSC1	-1.3861	4.3087	-1.9651	61.0717
NCI-H510A	GDSC1	-1.3439	1.7562	-1.4065	64.6954
NCI-H1838	GDSC1	-1.3155	3.6033	-1.6976	61.5608
SBC-1	GDSC1	-1.3034	3.3214	-1.6175	61.8809
NCI-H847	GDSC1	-1.276	3.1333	-1.5465	61.9535
NCI-H1694	GDSC1	-1.2461	2.0983	-1.3401	63.2872
COR-L95	CTRP2	-1.2064	6.1846	-1.9864	46.4506
NCI-H1648	GDSC1	-1.1589	1.6889	-1.2064	63.0704
LK-2	GDSC1	-1.0792	0.8721	-1.085	63.1201
CAL-12T	GDSC1	-1.0494	2.8648	-1.2473	60.4993
PC-14	GDSC1	-1.0408	2.3905	-1.1599	61.0351
NCI-H661	GDSC1	-1.0406	4.8886	-1.767	58.132
Lu-165	GDSC1	-0.9708	3.3636	-1.2651	59.2344
COR-L88	CTRP2	-0.9635	3.9678	-1.1882	44.3961
SK-MES-1	CTRP2	-0.8523	4.2913	-1.1274	43.7767
NCI-H1155	GDSC1	-0.8111	3.2346	-1.063	58.0172
NCI-H647	GDSC1	-0.7743	2.6127	-0.9076	58.2886
NCI-H3255	GDSC1	-0.7545	3.2709	-1.0093	57.4822
HARA [Human squamous cell lung carcinoma]	GDSC1	-0.7243	3.0435	-0.9296	57.4161
NCI-H1623	CTRP2	-0.6819	4.9243	-1.0773	42.9166
DMS 53	GDSC1	-0.6145	2.0192	-0.6645	57.1336
NCI-H1792	GDSC1	-0.5731	2.7169	-0.708	56.2182
LXF 289	CTRP2; CTRP1	-0.566	1.6978	-0.571	41.3294
Ms-1	GDSC1	-0.5587	3.1014	-0.7617	55.8068
NCI-H510A	CTRP2	-0.5365	2.9417	-0.5991	41.3057
LUDLU-1	CTRP2	-0.5248	5.6438	-1.0881	42.2446
LC-1/sq	GDSC1	-0.5165	3.2898	-0.7549	55.2767
HCC1588	CTRP2	-0.5157	3.7633	-0.6738	41.3972
NCI-H226	GDSC1	-0.4702	3.2609	-0.6983	54.8492
NCI-H1568	GDSC1	-0.462	2.7458	-0.5933	55.0645
NCI-H2081	GDSC1	-0.4598	3.9737	-0.8599	54.3477
RERF-LC-KJ	GDSC1	-0.4515	2.8275	-0.5955	54.9104
NCI-H1975	GDSC1	-0.4484	1.5214	-0.4608	55.4714
NCI-H1581	CTRP2	-0.4209	2.6401	-0.4563	40.4687
NCI-H1703	CTRP2	-0.3785	3.5197	-0.4937	40.399
NCI-H2196	GDSC1	-0.3442	4.3865	-0.8518	53.1377
DMS 79	CTRP2	-0.3332	10.6518	-2.6988	43.532
NCI-H292	GDSC1	-0.3264	3.6785	-0.6378	53.2593
UMC-11	GDSC1	-0.2893	1.0675	-0.2905	53.6049
NCI-H187	GDSC1	-0.2545	3.3381	-0.4805	52.6723
NCI-H2405	CTRP2	-0.2507	6.198	-0.9485	40.8408
BEN	GDSC1	-0.2405	3.231	-0.4428	52.5625
NCI-H1693	GDSC1	-0.215	4.0354	-0.6096	52.0829
NCI-H2595	GDSC1	-0.2123	6.9965	-1.6584	51.4426
NCI-H2347	GDSC1	-0.2041	2.7249	-0.3133	52.3083
DMS 273	CTRP2	-0.1913	5.3763	-0.6533	40.0017
EKVX	GDSC1	-0.1825	36.9306	-16.0688	50.2689
HCC1438	CTRP2	-0.1807	2.8034	-0.2175	38.8797
NCI-H2141	GDSC1	-0.157	3.7857	-0.4799	51.5804
NCI-H1963	GDSC1	-0.1385	2.7672	-0.2494	51.5706
NCI-H1688	GDSC1	-0.1184	1.5871	-0.1261	51.4631
NCI-H1944	CTRP2	-0.0798	5.2648	-0.5033	39.2159
LCLC-103H	GDSC1	-0.0263	3.453	-0.2577	50.2802
NCI-H1568	CTRP2	0.0147	4.4489	-0.2193	38.1404
NCI-H1581	GDSC1	0.0148	3.0536	-0.1322	49.8347
NCI-H1623	GDSC1	0.0364	3.6589	-0.2375	49.6193
NCI-H460	CTRP2	0.1158	3.9807	-0.0298	37.235
HCC95	CTRP2	0.1427	1.7394	0.142	36.6165
IST-SL1	GDSC1	0.1595	3.4701	-0.0594	48.2687
RERF-LC-MS	GDSC1	0.1825	2.508	0.1265	47.8215
NCI-H2369	GDSC1	0.1925	4.4777	-0.2949	48.1429
HCC78	CTRP2	0.1949	3.3893	0.1279	36.479
Lu-139	GDSC1	0.1979	3.6355	-0.0557	47.8827
NCI-H2110	CTRP2	0.2143	4.0973	0.0577	36.6188
NCI-H2803	GDSC1	0.2168	4.2446	-0.198	47.8403
Lu-65	GDSC1	0.2556	4.3541	-0.1883	47.476
COR-L105	GDSC1	0.275	3.797	-0.0117	47.0885
NCI-H23	GDSC1	0.2768	2.852	0.1828	46.7628
NCI-H522	CTRP2	0.2909	3.5412	0.2136	35.8741
DMS 454	CTRP2	0.3485	3.8764	0.234	35.6074
NCI-H1651	CTRP2	0.354	8.5996	-1.1386	38.8659
NCI-H1666	GDSC1	0.3808	2.8093	0.3001	45.4936
NCI-H650	GDSC1	0.3934	4.9255	-0.2226	46.3238
NCI-H2591	GDSC1	0.4401	4.4218	-0.0079	45.5969
NCI-H810	CTRP2	0.441	4.3612	0.2576	35.2065
NCI-H838	GDSC1	0.4639	2.0608	0.4528	44.251
SHP-77	GDSC1	0.4778	2.4143	0.446	44.16
NCI-H520	CTRP2	0.4807	4.3628	0.3001	34.9366
ChaGo-K-1	GDSC1	0.5119	4.9973	-0.1191	45.1932
SW1271	GDSC1	0.5332	3.8195	0.2643	44.2095
NCI-H64	GDSC1	0.5395	3.0597	0.4324	43.6703
NCI-H1915	GDSC1	0.5431	3.2916	0.3945	43.759
NCI-H596	GDSC1	0.5804	3.9293	0.2871	43.745
NCI-H69	GDSC1	0.6232	4.5561	0.1492	43.7383
NCI-H1563	GDSC1	0.6861	3.6325	0.4767	42.2823
NCI-H1836	GDSC1	0.6929	3.4417	0.5265	42.0505
DMS 114	GDSC1	0.708	6.908	-0.6582	44.6202
NCI-H2171	GDSC1	0.7458	2.7613	0.6944	40.9383
NCI-H2135	GDSC1	0.7593	4.0179	0.4585	41.75
COR-L95	GDSC1	0.7819	9.7223	-1.8445	45.5596
PaCa-3	GDSC1	0.784	3.7721	0.5498	41.2295
RERF-LC-Sq1	GDSC1	0.7878	4.2878	0.4118	41.6782
NCI-H720	GDSC1	0.7901	3.6825	0.5783	41.074
NCI-H524	GDSC1	0.8014	3.0426	0.7164	40.4104
NCI-H1339	CTRP2	0.871	4.2355	0.741	32.1958
NCI-H1092	GDSC1	0.9029	5.7139	0.0355	41.8972
HCC33	GDSC1	0.9151	2.5734	0.8902	38.7044
MOR/CPR	CTRP2	0.935	2.0773	0.9349	31.3412
NCI-H358	CTRP2	0.9444	2.9066	0.9352	31.3089
HOP-92	GDSC1	0.9585	3.4983	0.803	38.8263
NCI-H1869	GDSC1	0.9591	3.1609	0.8671	38.5112
NCI-H2087	CTRP2	0.9778	5.7934	0.51	32.5672
NCI-H1793	GDSC1	0.9914	3.0474	0.9191	38.0122
NCI-H1573	GDSC1	1.0039	2.7174	0.9712	37.6417
NCI-H1436	GDSC1	1.0501	3.1649	0.9643	37.359
NCI-H322M	GDSC1	1.101	5.0341	0.5038	39.0213
NCI-H2461	GDSC1	1.1049	7.8529	-0.6645	42.1498
Calu-3	CTRP2	1.109	5.4016	0.7588	31.3397
NCI-H2373	GDSC1	1.1509	4.6994	0.6751	37.991
RERF-LC-A1	CTRP2	1.1674	4.5295	1.0115	30.3157
DMS 79	GDSC1	1.1887	9.9184	-1.5366	43.1343
NCI-H1395	CTRP2	1.2563	6.6611	0.5437	31.5295
NCI-H1092	CTRP2	1.3146	7.4567	0.3245	31.9983
NCI-H82	GDSC1	1.3797	3.8345	1.1838	33.9191
NCI-H1650	CTRP2	1.4077	3.8553	1.3591	28.3575
T3M-10	CTRP2	1.4177	4.5114	1.2843	28.5783
NCI-H2023	CTRP2	1.4308	8.6194	-2.0306	20.4491
NCI-H841	GDSC1	1.4401	3.7385	1.2732	33.0114
NCI-H2196	CTRP2	1.4465	4.1857	1.3633	28.2165
NCI-H292	CTRP2	1.461	4.6096	1.314	28.3368
HCC15	CTRP2	1.4874	10.1016	-0.5763	33.8428
RERF-LC-MS	CTRP2	1.5074	5.4714	1.1755	28.6576
NCI-H69	CTRP2	1.5477	6.2936	0.9806	29.1825
NCI-H513	GDSC1	1.6038	3.5047	1.5016	30.5938
NCI-H196	GDSC1	1.6048	3.7566	1.4483	30.9169
NCI-H1184	CTRP2	1.6078	9.1313	-2.1377	20.431
LK2	CTRP2	1.6227	2.3891	1.6227	26.7639
HCC366	CTRP2	1.6463	6.0079	1.1766	28.2108
NCI-H322	CTRP2	1.6692	5.0958	1.4426	27.227
PC-14	CTRP2	1.6719	3.5946	1.6534	26.4981
HARA [Human squamous cell lung carcinoma]	CTRP2	1.6752	3.174	1.6712	26.4274
HCC44	CTRP2	1.731	4.2563	1.657	26.2925
NCI-H647	CTRP2	1.7646	6.1335	1.2672	27.5292
NCI-H838	CTRP2	1.7703	3.7723	1.7447	25.8669
HCC827	GDSC1	1.7927	2.6896	1.7891	27.6136
NCI-H650	CTRP2	1.7928	12.8682	-1.5257	34.9907
NCI-H2795	GDSC1	1.7994	4.9927	1.2695	30.7865
Lu-65	CTRP2	1.8033	7.3259	0.8974	28.6524
NCI-H2731	GDSC1	1.821	3.6483	1.708	27.958
NCI-H2030	CTRP2	1.8692	2.664	1.8692	25.123
NCI-H446	CTRP2	1.8775	6.281	1.3434	26.9149
COR-L51	CTRP2	1.8901	5.9913	1.4473	26.5152
SHP-77	CTRP2	1.9092	3.7864	1.8879	24.928
NCI-H2009	CTRP2	1.91	9.5134	0.1151	30.7257
NCI-H2722	GDSC1	1.926	5.9856	0.9997	31.5165
LOU-NH91	GDSC1	2.015	4.0782	1.8119	26.1312
NCI-H1869	CTRP2	2.0228	3.6379	2.0123	24.1358
NCI-H2869	GDSC1	2.0485	5.3418	1.3975	28.5728
DMS 114	CTRP2	2.0523	6.9933	1.2878	26.5714
LOU-NH91	CTRP2	2.0601	3.9143	2.0363	23.9323
NCI-H2085	GDSC1	2.0831	7.339	0.551	32.7817
NCI-H1435	CTRP2; CTRP1	2.1109	3.6031	2.1034	23.5175
HOP-62	CTRP2	2.1533	6.1277	1.6922	24.8436
LC-1/sq-SF	CTRP2	2.224	3.9282	2.2054	22.8238
NCI-H2122	CTRP2	2.2351	4.5501	2.1553	22.9582
VMRC-LCD	CTRP2	2.2809	3.7237	2.2731	22.4089
NCI-H1666	CTRP2	2.3565	4.6969	2.2634	22.196
NCI-H345	GDSC1	2.3792	4.6013	2.037	22.5558
NCI-H1755	GDSC1	2.3811	6.4635	1.2514	27.6171
NCI-H841	CTRP2	2.418	5.7248	2.1009	22.5771
COLO 699	CTRP2	2.4213	3.9057	2.4099	21.4865
NCI-H1373	CTRP2	2.4235	4.5006	2.3628	21.639
NCI-H1838	CTRP2	2.4515	3.8029	2.4446	21.2705
NCI-H2106	CTRP2	2.4572	4.9083	2.3359	21.6238
NCI-H446	GDSC1	2.489	4.1168	2.3176	20.0192
SK-LU-1	CTRP2	2.5112	8.1699	-0.9361	12.3278
NCI-H2286	CTRP2; CTRP1	2.5422	4.8244	2.4423	20.9841
NCI-H889	CTRP2	2.5509	4.2451	2.5235	20.6779
NCI-H2291	CTRP2	2.6054	6.5968	2.0262	22.2869
SW1271	CTRP2	2.621	6.5425	2.0621	22.1099
NCI-H2227	GDSC1	2.7071	4.6039	2.3879	18.3354
A-549	CTRP2	2.723	7.7576	1.7055	23.122
HCC1833	CTRP2	2.7447	4.5429	2.6986	19.4515
NCI-H1792	CTRP2	2.7468	5.794	2.44	20.3577
NCI-H2029	CTRP2	2.7965	6.0315	2.4225	20.272
NCI-H2029	GDSC1	2.8105	4.1894	2.6456	15.9663
NCI-H1563	CTRP2	2.8184	4.1545	2.8069	18.8439
HCC2108	CTRP2	2.8461	4.3896	2.8204	18.7074
HCC827	CTRP2	2.9244	3.8516	2.9231	18.1044
NCI-H196	CTRP2	2.9312	4.6744	2.8808	18.225
KNS-62	CTRP2	2.9739	4.6213	2.9324	17.9104
NCI-H1993	GDSC1	3.0087	4.1918	2.8603	13.3819
NCI-H2818	GDSC1	3.0149	4.4766	2.7655	14.0172
NCI-H727	CTRP2	3.0495	6.764	2.4436	19.4563
ChaGo-K-1	CTRP2	3.1126	5.0511	3.0177	17.1716
NCI-H2126	CTRP2	3.162	8.1612	-0.4621	8.4378
NCI-H661	CTRP2	3.1637	6.0342	2.8213	17.7206
NCI-H226	CTRP2	3.2136	4.4423	3.1993	16.2228
NCI-H1930	CTRP1	3.2249	11.7172	0.4114	43.4572
Sq-1	CTRP2	3.279	4.8582	1.0986	0.6288
NCI-H2444	GDSC1	3.3372	7.8388	1.5036	21.5246
LCLC-103H	CTRP2	3.4433	5.0311	3.3776	14.8697
EBC-1	CTRP2	3.4529	12.6392	-2.4374	17.2177
HCC1195	CTRP2	3.4744	4.3743	3.4703	14.4531
NCI-H1299	CTRP2	3.5087	5.3772	3.3807	14.653
NCI-H1693	CTRP2	3.5569	7.5835	2.6499	17.268
HCC2935	CTRP2	3.5586	6.4239	3.1159	15.4761
CAL-12T	CTRP2	3.6444	5.1981	3.5653	13.5782
COR-L105	CTRP2	3.6706	7.0879	2.9767	15.6959
NCI-H1355	CTRP2	3.734	5.5311	3.5892	13.2145
Calu-6	CTRP2	3.7645	5.7987	0.9454	0.8009
LCLC-97TM1	CTRP2	3.8086	5.0559	3.7655	12.3614
NCI-H2342	CTRP2	3.8127	8.5003	2.5028	17.1764
NCI-H2444	CTRP2	3.8796	4.7705	3.8693	11.7771
NCI-H441	CTRP2	4.0098	5.5061	3.8962	11.2698
RERF-LC-Ad1	CTRP2	4.0311	6.2862	3.6745	12.0234
NCI-H2172	CTRP2	4.1019	5.6575	3.9573	10.7685
BEN	CTRP2	4.1485	6.8386	3.581	12.0577
HOP-92	CTRP2	4.2042	7.0459	3.551	12.0271
HCC2279	CTRP2	4.2855	5.3392	4.2321	9.2235
RERF-LC-KJ	CTRP1	4.3396	7.4606	3.5041	25.0388
NCI-H1755	CTRP2	4.4606	6.0993	1.107	0.151
Calu-1	CTRP2	4.5574	7.7961	3.5677	11.0667
HCC4006	CTRP2	4.758	5.7336	4.6512	6.2727
NCI-H1915	CTRP2; CTRP1	4.8236	6.2637	4.5271	6.5566
EKVX	CTRP2	5.0915	7.5636	4.1922	7.2519
NCI-H1793	CTRP2	5.1296	5.9837	4.9636	4.0335
RERF-LC-Ad2	CTRP2	5.1867	9.0848	3.529	9.8007
IA-LM	CTRP2	5.8594	7.2384	5.0183	2.2392
NCI-H2291	GDSC1	6.1449	12.9314	1.1707	14.2181
HCC1171	CTRP2	6.8597	10.3575	4.207	4.0522
Hs 888.Lu	CTRP2	3.1219	9.3931	1.4024	23.1205

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CBTCi002-A	GDSC1	1.6194	4.3689	1.2926	31.7584

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
P-STS	CTRP2	-2.0335	5.1536	-2.606	50.8973
SYO-1	CTRP2	-0.9517	7.1785	-2.0248	45.3242
H-STS	CTRP2	1.4711	2.3137	1.471	27.7731

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
U-CH1	CTRP2	2.3809	5.7201	2.0618	22.8302

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Soft Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Aska-SS	CTRP2	7.5791	12.5901	3.6208	5.3991
Yamato-SS	CTRP2	10.41	21.2326	1.3729	9.9741
SW872	GDSC1	-5.2809	-2.5581	-5.2822	95.2946
VA-ES-BJ	GDSC1	-4.0338	2.7381	-4.458	76.2493
KYM-1	GDSC1	-3.9868	-1.1239	-3.9924	88.6632
SW982	GDSC1	-3.5887	0.5747	-3.6565	81.3003
SK-UT-1	GDSC1	-3.553	0.1926	-3.5931	82.5058
A-204	GDSC1	-3.4701	1.323	-3.6078	78.4609
G-402	GDSC1	-3.398	2.4062	-3.7011	75.084
KYM-1	CTRP2	-3.347	1.0387	-3.3907	59.3557
MFH-ino	GDSC1	-3.3454	-0.8305	-3.3491	85.4379
EW-8	GDSC1	-3.0442	-1.1126	-3.0448	84.8638
MES-SA	GDSC1	-2.9131	0.2228	-2.9354	79.7181
Hs 633.T	GDSC1	-2.414	0.9245	-2.4579	74.7222
TE 617.T	CTRP2	-1.9822	4.3371	-2.3618	50.6535
G-401	CTRP2	-1.811	4.8477	-2.2891	49.6769
STS-0421	GDSC1	-1.7383	2.2208	-1.8816	66.9937
HT-1080	GDSC1	-1.5186	1.9286	-1.609	65.8882
G-402	CTRP2	-1.2135	5.1375	-1.7078	46.2479
SK-LMS-1	GDSC1	-1.1038	1.3163	-1.125	62.9715
A-204	CTRP2	-0.8925	4.0268	-1.1219	43.9544
TE 441.T	CTRP2	-0.6964	3.0313	-0.7754	42.3976
G-401	GDSC1	-0.5518	3.2207	-0.7785	55.6581
Rh41	CTRP2	-0.1362	2.6896	-0.1646	38.559
RD	GDSC1	0.3406	4.3076	-0.0817	46.5839
TE 441.T	GDSC1	0.4569	3.6145	0.2313	44.9634
MES-SA	CTRP2	0.7475	3.1875	0.7208	32.6771
Rh30	GDSC1	0.7818	2.6101	0.7477	40.4098
Rh41	GDSC1	0.8827	4.2288	0.5329	40.5218
Hs 729.T	CTRP2	1.8143	6.6579	1.1495	27.776
RD	CTRP2	2.0089	6.4099	1.4441	26.16
GCT	GDSC1	2.0864	3.4247	2.036	24.2411
RKN	GDSC1	2.2607	4.5747	1.9188	24.0163
GCT	CTRP2	2.695	4.9756	2.5804	20.0189
SK-UT-1	CTRP2	2.7266	6.643	2.1406	21.5129
HT-1080	CTRP2	2.9056	6.6921	2.3155	20.3469
RKN	CTRP2	3.7365	4.8647	1.2721	0.0768
Rh18	CTRP2	4.3238	5.3515	4.2712	8.9659
SK-LMS-1	CTRP2	4.3476	7.9126	3.3065	12.6364
SW684	GDSC1	4.9083	8.0104	2.692	7.4213
BT-12	CTRP2	6.9084	11.0686	3.8993	5.2142
BT-16	CTRP2	7.3102	14.8911	2.3247	10.8537
SW982	CTRP2	7.5786	8.9822	5.1858	0.2008
TTC-709	CTRP2	8.3547	24.9749	-1.866	22.0699
Tm87-16	CTRP2	9.6204	31.0827	-3.9329	24.4812

Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Ovary Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
2004	CTRP2	9.683	21.0791	0.9773	12.1758
A2780	GDSC1	-4.9809	1.2014	-5.2031	82.6366
IGROV-1	GDSC1	-4.3238	2.0119	-4.6286	78.9391
TYK-nu	GDSC1	-4.1525	4.2597	-4.9693	73.1487
OAW42	GDSC1	-3.6778	2.1247	-3.9516	76.7991
TOV-112D	GDSC1	-3.6089	-1.8476	-3.609	90.3158
SK-OV-3	GDSC1	-3.312	2.5703	-3.6398	74.3406
OC 314	GDSC1	-2.9323	-1.4955	-2.9323	85.1949
OVTOKO	GDSC1	-2.9228	2.3019	-3.1684	73.4834
OVCAR-8	GDSC1	-2.4648	2.2303	-2.6628	71.4692
Caov-3	GDSC1	-2.4061	0.7925	-2.4414	75.0464
OV-90	GDSC1	-1.875	2.218	-2.0276	67.9533
Kuramochi	GDSC1	-1.5663	4.4748	-2.2107	61.9689
OAW28	GDSC1	-1.1951	4.0809	-1.6918	60.0768
OVCAR-5	GDSC1	-1.028	3.1823	-1.2875	59.9207
OC 314	CTRP2	-0.8078	1.3239	-0.8103	42.9479
OVCAR-4	GDSC1	-0.4949	3.0068	-0.6743	55.2441
OAW42	CTRP2	-0.4661	3.2275	-0.5526	40.9023
TOV-112D	CTRP2	-0.4042	2.5135	-0.4319	40.3367
EFO-21	GDSC1	-0.3735	6.6172	-1.6759	52.5987
COV434	CTRP2	-0.1117	4.3219	-0.3321	38.9257
Caov-4	GDSC1	-0.0511	5.17	-0.788	50.4384
OVCAR-3	GDSC1	-0.021	3.8558	-0.3497	50.2128
ES-2	GDSC1	0.1669	2.9764	0.0452	48.0897
TOV-21G	CTRP2	0.1802	2.5836	0.1655	36.4124
OV7	CTRP2	0.2557	4.7627	-0.0214	36.6915
EFO-27	GDSC1	0.2766	3.7274	0.0076	47.0467
Caov-3	CTRP2	0.3589	8.5929	-2.9589	27.4154
TOV-21G	GDSC1	0.5151	2.0095	0.507	43.6006
ONCO-DG-1	CTRP2	0.7494	3.9053	0.6572	32.8796
A2780	CTRP2	1.0664	7.7152	-0.0383	33.8481
OVTOKO	CTRP2	1.1291	5.6125	0.7253	31.3806
OV56	CTRP2	1.4407	5.2736	1.1524	28.9507
HEY A8	CTRP2	1.5031	2.1072	1.2802	2.3847
OVKATE	GDSC1	1.6403	4.2444	1.3541	31.2661
RMG-I	GDSC1	1.8191	3.3856	1.7552	27.667
DOV13	CTRP2	1.8581	7.0567	1.0556	27.9572
OV-90	CTRP2	1.8991	4.4905	1.8044	25.245
TYK-nu	CTRP2	1.9522	4.5802	0.4157	6.1716
SNU-119	CTRP2	2.0031	3.5921	1.9938	24.2629
COV362	CTRP2	2.0604	5.3433	1.8109	24.7108
ES2	CTRP2	2.0764	3.8399	2.0578	23.8064
OVISE	GDSC1	2.1656	7.2011	0.6967	31.6762
JHOC-5	CTRP2	2.1683	3.5979	2.1621	23.1529
JHOS-2	CTRP2	2.3877	7.2053	1.5685	24.5834
SNU-8	CTRP2	2.3909	3.6047	2.3878	21.6609
IGROV-1	CTRP2	2.4656	5.0151	2.3246	21.6367
COV644	CTRP2	2.6436	4.6849	2.5728	20.209
OVSAHO	CTRP2	2.8602	4.1532	2.8499	18.5614
OVK18	CTRP2	3.1728	8.8954	-0.8093	10.2277
OVCAR-5	CTRP2	3.5263	5.8443	3.2752	14.9792
FU-OV-1	GDSC1	3.5689	5.0352	3.0904	8.904
OVCAR-4	CTRP2	3.6155	4.6052	3.6056	13.5332
OVISE	CTRP2	3.8244	4.4927	3.8228	12.115
EFO-27	CTRP2	3.8474	6.2001	3.5075	13.1774
MCAS	CTRP2	3.8594	5.5498	3.7213	12.3572
Kuramochi	CTRP2	3.8692	5.5612	3.7291	12.2991
OVCAR-8	CTRP2	3.9047	5.0906	3.8633	11.7154
OAW28	CTRP2	3.9736	6.5056	3.5302	12.7334
EFO-21	CTRP2	3.994	8.0493	2.8906	15.185
RMG-I	CTRP2	4.1612	7.9082	0.2669	3.1618
OVMANA	CTRP1	4.2026	4.7029	4.2018	20.5323
FU-OV-1	CTRP2	4.3258	5.9143	4.1234	9.4934
JHOS-4	CTRP1	4.4334	6.8632	3.865	21.7218
SNU-840	CTRP2	4.4774	6.2924	1.0466	0.2357
COV318	CTRP1	4.9354	7.7631	3.946	18.3135
JHOM-1	CTRP2	4.9516	5.6401	4.8894	4.8248
SK-OV-3	CTRP2	5.6707	12.7689	-1.0394	7.1128

Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Pleura Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H28	CTRP2	-0.9983	2.557	-1.0508	44.3241
MPP 89	GDSC1	-0.3194	4.4773	-0.8524	52.8888
MSTO-211H	CTRP2	0.2804	3.7206	0.1817	36.0095
NCI-H2052	GDSC1	0.6022	8.1576	-1.3113	46.0639
NCI-H28	GDSC1	1.1756	4.2104	0.8577	37.004
MSTO-211H	GDSC1	1.2807	4.4801	0.8886	36.1281
IST-Mes1	GDSC1	2.0643	5.0308	1.5379	27.617
MPP 89	CTRP2	2.1611	8.318	0.8844	27.6078
NCI-H2052	CTRP2	2.2769	7.6598	1.2738	25.9478
NCI-H2452	CTRP2	3.0958	6.2924	2.6623	18.507
NCI-H2452	GDSC1	3.1665	5.1402	2.6432	14.1553
IST-Mes1	CTRP2	4.0383	7.8695	3.0169	14.5705
ACC-MESO-1	CTRP2	4.1025	4.9147	4.0913	10.2963
JL-1	CTRP2	4.945	5.6373	4.883	4.8679

Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Prostate Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
DU145	GDSC1	-4.5322	-2.2845	-4.5327	94.038
22Rv1	GDSC1	-3.0527	1.6196	-3.2016	75.9481
LNCaP clone FGC	GDSC1	-1.1877	2.5583	-1.3431	62.0943
22Rv1	CTRP2	-0.0069	3.8724	-0.1452	38.0213
LNCaP clone FGC	CTRP2	0.0261	4.8011	-0.2791	38.2518
VCaP	GDSC1	0.8631	5.0028	0.2585	41.5736
DU145	CTRP2	1.1455	7.0987	0.2725	32.7115
PC-3	GDSC1	1.7719	5.7614	0.9342	32.7594
VCaP	CTRP2	3.0282	5.0891	2.9194	17.7817
PaCa-3	CTRP2; CTRP1	4.7708	7.0007	4.1486	8.1939

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Salivary Gland Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
A-253	GDSC1	-1.3825	1.4288	-1.4201	65.5733
YD-15	CTRP2	-1.3419	0.6932	-1.3429	46.4973
A-253	CTRP2	0.756	3.8966	0.6654	32.8303

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuTu 80	GDSC1	-4.9294	-1.8167	-4.9346	92.6309

Cancer Drug Sensitivity Data Curated from 58 Cell Line(s) in Stomach Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NUGC-3	GDSC1	-5.0516	-0.4314	-5.1076	87.8928
HGC-27	GDSC1	-4.7533	-0.9072	-4.7767	89.1859
23132/87	GDSC1	-3.6289	-1.4332	-3.6298	88.8142
AGS	GDSC1	-3.5147	1.0394	-3.6222	79.5123
SNU-1	GDSC1	-2.9945	1.053	-3.0754	77.4188
SNU-16	CTRP2	-2.9386	1.5195	-2.9968	56.7647
TMK-1	GDSC1	-2.8289	1.1322	-2.9088	76.397
MKN45	GDSC1	-2.7058	1.4328	-2.8099	74.8883
SNU-5	GDSC1	-2.6997	2.4275	-2.9501	72.144
GSS	CTRP2	-2.6928	1.4483	-2.7374	55.2801
SNU-5	CTRP2	-2.6034	-0.0651	-2.6053	54.8761
MKN28	GDSC1	-2.5719	2.4104	-2.8091	71.5658
NCI-N87	CTRP2	-2.465	2.1781	-2.5542	53.747
NUGC-4	GDSC1	-2.4082	-0.0022	-2.4145	77.2669
RF-48	GDSC1	-1.9488	1.9923	-2.0744	68.9565
IM95	GDSC1	-1.4314	2.3529	-1.5726	64.4227
OCUM-1	GDSC1	-1.3029	1.1469	-1.3219	65.2173
GCIY	GDSC1	-1.2788	3.9328	-1.7427	60.8506
NCI-N87	GDSC1	-1.1999	4.619	-1.8552	59.4767
MKN1	GDSC1	-1.0901	1.4782	-1.1198	62.6484
23132/87	CTRP2	-1.0563	2.6843	-1.1215	44.7283
ECC12	CTRP2	-0.9501	1.4394	-0.9552	43.9014
TGBC11TKB	GDSC1	-0.3906	2.0971	-0.4365	54.6001
SNU-1	CTRP2	-0.0227	5.5017	-0.502	38.9862
SNU-620	CTRP2	-0.0162	3.9856	-0.1721	38.131
NUGC-4	CTRP2	0.1024	3.0958	0.0565	37.028
Fu97	GDSC1	0.3463	1.8733	0.3391	45.7001
IM95	CTRP2	0.3567	3.1535	0.3174	35.3175
SNU-719	CTRP2	0.5042	4.516	0.2976	34.8611
HGC-27	CTRP2	0.7038	4.814	0.4544	33.6804
SNU-668	CTRP2	1.1865	4.7146	0.998	30.2978
HSC-39	GDSC1	1.3198	3.3899	1.2162	34.1266
AGS	CTRP2	1.3848	4.252	1.2886	28.6707
NUGC-3	CTRP2	1.3859	8.5949	-2.0565	20.6908
RERF-GC-1B	GDSC1	1.4216	5.0108	0.8573	35.334
OCUM-1	CTRP2	1.6471	4.7939	1.4812	27.1651
HuG1-N	CTRP2	1.6627	3.5737	1.645	26.5569
Fu97	CTRP2	1.6942	2.8155	1.6937	26.2893
ECC10	GDSC1	1.7467	4.7748	1.293	30.9699
SNU-601	CTRP2	1.8154	6.3158	1.2646	27.3793
ECC10	CTRP2	2.3248	4.0711	2.3007	22.1716
MKN45	CTRP2	2.3295	3.4973	2.3274	22.0665
SNU-16	GDSC1	2.7842	4.2666	2.5918	16.4849
Hs 746.T	CTRP2	3.1999	7.1551	2.4527	18.9983
MKN1	CTRP2	3.5931	4.6707	3.5783	15.8312
SCH	GDSC1	3.6784	4.284	3.545	4.954
LMSU	CTRP2	3.9096	6.6811	3.3934	13.4347
MKN7	GDSC1	3.9425	6.1445	2.8795	9.0431
KATO III	CTRP2	4.1644	7.2179	3.4354	12.5869
MKN74	CTRP2; CTRP1	4.7053	6.0096	4.5007	6.9857
SNU-216	CTRP2	4.7954	6.7775	4.2749	7.6258
KE-39	CTRP2	4.8581	7.7616	3.8755	9.0939
SH-10-TC	CTRP2	5.0399	5.4783	5.0215	4.0825
MKN7	CTRP2	5.1747	6.0421	4.9868	3.8214
SNG-M	GDSC1	-2.8482	1.4049	-2.9577	75.6682
SNU-685	CTRP2	2.6922	6.1996	2.2553	21.193
SNU-1077	CTRP2	3.7724	4.5245	3.7695	12.4653
SNG-M	CTRP2; CTRP1	3.7848	5.3509	3.6868	12.7109

Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Thyroid Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TT2609-C02	GDSC1	-5.4538	-0.8207	-5.5009	89.5766
IHH-4	GDSC1	-4.3142	-2.1048	-4.3148	93.1021
ML-1 [Human leukemia]	GDSC1	-4.0943	2.3273	-4.4395	77.4836
CGTH-W-1	GDSC1	-4.0162	0.3827	-4.088	83.2073
8305C	GDSC1	-2.6784	2.4323	-2.9279	72.0305
B-CPAP	GDSC1	-1.8182	2.6575	-2.0399	66.6488
CAL-62	GDSC1	-1.6652	1.4288	-1.7147	68.0579
8505C	GDSC1	-1.632	1.9414	-1.7309	66.767
ML-1 [Human leukemia]	CTRP2	-1.3896	3.1879	-1.5274	46.9827
FTC-133	GDSC1	-0.8274	1.7964	-0.8686	59.5898
KMH-2	GDSC1	-0.4714	2.9466	-0.6378	55.0457
ASH-3	GDSC1	-0.218	3.5536	-0.4895	52.2412
CGTH-W-1	CTRP2	-0.1944	4.3909	-0.4345	39.5107
K5	GDSC1	0.3773	6.5795	-0.8674	47.1271
SW579	CTRP2	0.4328	4.4982	0.2237	35.338
FTC-133	CTRP2	0.6453	4.1449	0.5129	33.6991
BHT-101	GDSC1	0.6527	3.4735	0.4761	42.5609
8305C	CTRP2	0.7947	4.3461	0.6413	32.7772
CAL-62	CTRP2	1.0025	4.4055	0.8551	31.381
BHT-101	CTRP2	1.2542	3.6661	1.2147	29.3485
FTC-238	CTRP2	1.4452	3.7328	1.409	28.0664
TT	CTRP2	1.6905	3.1316	1.6873	26.323
TT	GDSC1	1.8271	3.8413	1.67	28.1655
8505C	CTRP2	1.8865	4.5048	1.7888	25.3393
HTC-C3	GDSC1	2.1727	5.3304	1.5329	27.038
B-CPAP	CTRP2	3.0821	8.3679	1.8204	21.7036
WRO	GDSC1	3.3978	6.9444	2.0001	17.8932
TT2609-C02	CTRP2	3.8659	10.8327	1.4513	21.0423

Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Upper Aerodigestive Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JHU-011	GDSC1	-5.5371	-0.8749	-5.584	89.8138
KON	GDSC1	-4.7769	-1.6289	-4.7832	91.8308
PCI-06A	GDSC1	-4.6248	0.6403	-4.7524	83.6973
CAL-27	GDSC1	-4.5593	-0.0681	-4.6205	85.932
PCI-04B	GDSC1	-4.1737	-0.2756	-4.2087	85.9078
HSC-3	GDSC1	-3.8724	0.5801	-3.954	82.1477
BB30-HNC	GDSC1	-3.8058	-0.7416	-3.8161	86.7254
BHY	GDSC1	-3.7302	0.3062	-3.7841	82.6742
Ca9-22	GDSC1	-3.601	0.5073	-3.664	81.5706
HSC-2	GDSC1	-3.4224	-0.5811	-3.4307	84.838
OSC-20	GDSC1	-2.8919	0.4674	-2.9253	78.809
FaDu	GDSC1	-2.7218	-0.2946	-2.7268	80.2791
NCI-H3118	GDSC1	-2.5719	2.7982	-2.8834	70.6213
HO-1-u-1	GDSC1	-2.2252	1.4222	-2.3015	72.1736
Detroit 562	GDSC1	-2.1731	0.6641	-2.1946	73.7878
JHU-029	GDSC1	-1.9619	3.6832	-2.4227	65.5476
SCC-4	GDSC1	-1.614	2.7165	-1.8301	65.1365
KOSC-2	GDSC1	-1.4997	3.161	-1.7955	63.5471
HO-1-N-1	GDSC1	-1.3596	2.0715	-1.4574	64.3131
BICR 22	CTRP2	-1.2426	3.2301	-1.3763	46.0402
HSC-4	GDSC1	-1.1567	1.6479	-1.2008	63.1034
OSC-19	GDSC1	-1.0922	6.1964	-2.2806	57.3133
BICR 31	GDSC1	-1.0867	3.4582	-1.4133	60.049
BB49-HNC	GDSC1	-0.997	1.3019	-1.0145	61.8514
CAL-33	GDSC1	-0.8154	1.9154	-0.866	59.3575
SAS	GDSC1	-0.7983	2.9788	-0.9972	58.156
PCI-38	GDSC1	-0.7477	2.2546	-0.8299	58.356
PE/CA-PJ15	GDSC1	-0.7445	3.8178	-1.1292	56.907
PCI-15A	GDSC1	-0.6915	3.4866	-0.9895	56.735
SCC-15	GDSC1	-0.5874	3.118	-0.7961	56.07
SCC-25	GDSC1	-0.5541	3.7001	-0.8914	55.3538
BICR 22	GDSC1	-0.5404	3.2226	-0.7665	55.5483
LB771-HNC	GDSC1	-0.4211	2.6299	-0.5316	54.6969
FaDu	CTRP2	-0.1736	3.1241	-0.2346	38.9027
PE/CA-PJ34 (clone C12)	CTRP2	-0.0387	3.9306	-0.1879	38.2603
HSC-3	CTRP2	0.0969	3.2983	0.0336	37.1174
PE/CA-PJ15	CTRP2	0.1068	5.5186	-0.3652	38.1544
BHY	CTRP2	0.1443	4.726	-0.1346	37.4193
JHU-022	GDSC1	0.2024	6.3326	-0.9524	48.4447
YD-10B	CTRP2	0.3348	3.9422	0.2102	35.7286
SCC-9	GDSC1	0.3756	4.0068	0.0427	46.0766
BICR 78	GDSC1	0.762	3.774	0.5253	41.4949
UPCI-SCC-090	GDSC1	1.0065	4.2946	0.6482	39.1439
DOK	GDSC1	1.0691	5.7093	0.2139	40.2268
Detroit 562	CTRP2	1.0926	3.7408	1.0386	30.4724
SNU-1076	CTRP2	1.2595	4.2486	1.1552	29.5312
BICR 10	GDSC1	1.2633	4.3715	0.9042	36.1724
CAL-27	CTRP2	1.3048	5.7603	0.8762	30.312
PE/CA-PJ41 (clone D2)	CTRP2	1.5879	5.4922	1.2579	28.1197
PE/CA-PJ49	CTRP2	1.7136	4.8892	1.5346	26.7682
HSC-2	CTRP2	1.7402	2.7307	1.74	25.9822
CAL-33	CTRP2	1.7652	4.4384	1.6687	26.142
PCI-30	GDSC1	2.2158	4.4934	1.8988	24.4028
SNU-1214	CTRP2	2.3667	4.44	2.3099	22.0035
SAT [Human HNSCC]	GDSC1	2.5141	5.8133	1.6795	24.2624
SCC-25	CTRP2	2.5254	5.0113	2.3901	21.2191
BICR 18	CTRP2	2.5676	7.2376	1.7482	23.4115
SCC-9	CTRP2	2.7402	5.6485	2.4738	20.2561
SNU-46	CTRP2	2.8655	4.9447	2.77	18.8178
SNU-899	CTRP2	2.8729	4.1423	2.8634	18.4745
SKN-3	GDSC1	3.0785	4.2409	2.9195	12.5868
YD-8	CTRP2	3.1396	5.2396	3.0097	17.1145
BICR 16	CTRP2	3.4285	5.2662	3.3179	15.125
SNU-1041	CTRP2	3.4437	4.4137	3.4377	14.6635
BICR 6	CTRP2	3.5631	5.248	3.4676	14.1769
HSC-4	CTRP2	3.6425	5.2447	1.1041	0.4076
SNU-1066	CTRP2	3.7335	5.773	3.5224	13.457
BICR 56	CTRP2	4.2604	5.0396	4.2463	9.2554
BICR 31	CTRP2	4.689	9.099	3.0678	12.7993

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Urinary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
J82	GDSC1	-6.5646	-2.0737	-6.5877	93.7355
5637	GDSC1	-4.907	0.4942	-5.0349	84.6597
639V	GDSC1	-4.0273	-2.5524	-4.0274	94.3529
SW1710	GDSC1	-3.4333	1.6524	-3.6127	77.3304
BFTC-905	GDSC1	-3.3409	-0.0878	-3.3616	82.7275
647V	GDSC1	-2.9866	-1.2425	-2.9868	84.8926
RT-112	GDSC1	-2.922	2.0835	-3.1304	74.0671
UM-UC-3	GDSC1	-2.6015	-0.7277	-2.6023	80.6335
CAL-29	GDSC1	-2.4755	0.925	-2.5219	75.0978
T24	GDSC1	-1.7761	2.5606	-1.977	66.5634
TCCSUP	GDSC1	-1.2957	2.6935	-1.4823	62.7778
647V	CTRP2	-0.7574	1.8397	-0.7679	42.6347
J82	CTRP2	-0.6648	5.4259	-1.1827	43.0139
UM-UC-1	CTRP2	-0.17	4.9146	-0.5178	39.6112
639V	CTRP2	0.195	2.513	0.1831	36.305
RT-4	GDSC1	0.2841	1.4333	0.2832	46.4528
5637	CTRP2	0.326	3.3413	0.2701	35.5743
253J	CTRP2	0.3497	5.1663	-0.0108	36.3141
VM-CUB-1	CTRP2	0.4472	2.9878	0.4216	34.6714
253J-BV	CTRP2	0.4671	5.5332	0.0242	35.7868
CAL-29	CTRP2	0.5644	2.9357	0.5451	33.8714
HT-1197	GDSC1	0.659	5.1107	-0.0001	43.7943
HT-1376	GDSC1	0.963	3.099	0.881	38.4123
JMSU-1	CTRP2	1.3536	3.8042	1.307	28.711
BC-3C	CTRP2	1.8745	4.4281	1.7871	25.3834
KU-19-19	GDSC1	1.9177	4.2511	1.6544	27.7259
BFTC-905	CTRP2	2.2423	3.8869	2.2265	22.6927
KU-19-19	CTRP2	2.3241	4.0375	2.3023	22.1684
T24	CTRP2	2.3377	6.5549	1.7514	24.076
SW780	GDSC1	2.5187	3.2845	2.5089	18.5773
TCCSUP	CTRP2	2.6075	5.4142	2.3899	20.9633
HT-1197	CTRP2	3.0013	5.734	2.7348	18.5219
SCaBER	CTRP2	3.0522	6.904	2.3935	19.6364
RT-112	CTRP2	3.9873	4.9787	3.9649	11.1011
UM-UC-3	CTRP2	4.0863	5.5953	1.1467	0.1726
HT-1376	CTRP2	4.1064	6.2119	0.9325	0.6343
SW1710	CTRP2	4.1249	4.9827	4.1093	10.1624
RT-4	CTRP2	4.4536	6.1222	1.0967	0.1659
U-BLC1	CTRP2	5.2956	6.1493	5.0637	3.203
KMBC-2	CTRP2	8.0991	9.9721	5.0294	0.3098

Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Urogenital System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HT-3	GDSC1	-6.6593	6.0003	-8.2346	75.3159
SiSo	GDSC1	-6.3794	-1.657	-6.4135	92.5419
NT2-D1	GDSC1	-5.6771	-3.1841	-5.6776	97.0892
Ca Ski	GDSC1	-4.9313	2.1614	-5.3135	79.8935
ME-180	GDSC1	-4.2871	0.3013	-4.3646	84.128
CAL-39	GDSC1	-3.8098	0.1073	-3.8539	83.6102
PA-1	GDSC1	-3.3961	-2.2923	-3.3961	90.801
DSH1	GDSC1	-3.2596	0.4238	-3.3032	80.6151
BPH-1	GDSC1	-3.2556	-1.1316	-3.2567	86.1042
SW962	GDSC1	-3.1074	2.2639	-3.3609	74.3592
SW954	GDSC1	-2.806	3.6682	-3.3397	69.7432
DoTc2 4510	GDSC1	-2.6596	1.5236	-2.7714	74.3912
MS751	GDSC1	-2.6388	1.9776	-2.8099	73.0256
C-4-I	GDSC1	-2.6258	0.9789	-2.6826	75.8064
NEC8	GDSC1	-2.4727	-0.2364	-2.4763	78.3701
KGN	GDSC1	-2.2801	2.0174	-2.4318	70.9802
HeLa	GDSC1	-1.9888	2.9872	-2.2896	67.0473
SKG-IIIa	GDSC1	-1.4176	3.8024	-1.8596	61.9811
OMC-1 [Human cervical carcinoma]	GDSC1	-1.3366	3.2605	-1.64	62.2166
C-33 A	GDSC1	-1.0758	2.2505	-1.1782	61.5373
SW756	GDSC1	-0.7266	4.5598	-1.3213	56.1614
HEC-1	GDSC1	-0.4744	1.5527	-0.4887	55.7698
OVMIU	GDSC1	-0.3837	3.3844	-0.6311	53.9423
NCC-IT	GDSC1	-0.279	3.0589	-0.4507	53.0183
LB831-BLC	GDSC1	-0.1304	2.417	-0.1944	51.5297
SKN	GDSC1	0.6672	4.1721	0.3144	42.9457
JEG-3	GDSC1	1.0064	4.8748	0.4583	39.8657
SiHa	GDSC1	1.2541	2.87	1.2198	34.5333
JAR	GDSC1	2.2359	3.3661	2.2036	22.2564
HeLa	CTRP2	3.6612	4.7437	3.6439	13.2538

Drug-Drug Interaction (DDI) Information of This Drug

Coadministration of a Drug Treating the Disease Different from Mitomycin (Comorbidity)

DDI Drug Name	DDI Drug ID	Severity	Mechanism	Comorbidity	REF
Roflumilast	DMPGHY8	Moderate	Additive immunosuppressive effects by the combination of Mitomycin and Roflumilast.	Asthma [CA23]	[10]
Ofloxacin	DM0VQN3	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Ofloxacin.	Bacterial infection [1A00-1C4Z]	[11]
Ciprofloxacin XR	DM2NLS9	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Ciprofloxacin XR.	Bacterial infection [1A00-1C4Z]	[11]
Trovafloxacin	DM6AN32	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Trovafloxacin.	Bacterial infection [1A00-1C4Z]	[11]
Sparfloxacin	DMB4HCT	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Sparfloxacin.	Bacterial infection [1A00-1C4Z]	[11]
Gemifloxacin	DMHT34O	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Gemifloxacin.	Bacterial infection [1A00-1C4Z]	[11]
Norfloxacin	DMIZ6W2	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Norfloxacin.	Bacterial infection [1A00-1C4Z]	[11]
ABT-492	DMJFD2I	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by ABT-492.	Bacterial infection [1A00-1C4Z]	[11]
Levofloxacin	DMS60RB	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Levofloxacin.	Bacterial infection [1A00-1C4Z]	[11]
Lomefloxacin	DMVRH9C	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Lomefloxacin.	Bacterial infection [1A00-1C4Z]	[11]
Grepafloxacin	DMGLX0T	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Grepafloxacin.	Bronchitis [CA20]	[11]
Teriflunomide	DMQ2FKJ	Major	Additive immunosuppressive effects by the combination of Mitomycin and Teriflunomide.	Hyper-lipoproteinaemia [5C80]	[12]
Denosumab	DMNI0KO	Moderate	Additive myelosuppressive effects by the combination of Mitomycin and Denosumab.	Low bone mass disorder [FB83]	[13]
Thalidomide	DM70BU5	Major	Additive thrombogenic effects by the combination of Mitomycin and Thalidomide.	Multiple myeloma [2A83]	[14]
Tecfidera	DM2OVDT	Moderate	Additive immunosuppressive effects by the combination of Mitomycin and Tecfidera.	Multiple sclerosis [8A40]	[15]
Siponimod	DM2R86O	Major	Additive immunosuppressive effects by the combination of Mitomycin and Siponimod.	Multiple sclerosis [8A40]	[16]
Fingolimod	DM5JVAN	Major	Additive immunosuppressive effects by the combination of Mitomycin and Fingolimod.	Multiple sclerosis [8A40]	[17]
Ocrelizumab	DMEZ2KH	Moderate	Additive immunosuppressive effects by the combination of Mitomycin and Ocrelizumab.	Multiple sclerosis [8A40]	[18]
Ozanimod	DMT6AM2	Major	Additive immunosuppressive effects by the combination of Mitomycin and Ozanimod.	Multiple sclerosis [8A40]	[10]
Omacetaxine mepesuccinate	DMPU2WX	Moderate	Additive immunosuppressive effects by the combination of Mitomycin and Omacetaxine mepesuccinate.	Myeloproliferative neoplasm [2A20]	[19]
Gatifloxacin	DMSL679	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Gatifloxacin.	Respiratory infection [CA07-CA4Z]	[11]
Canakinumab	DM8HLO5	Moderate	Additive immunosuppressive effects by the combination of Mitomycin and Canakinumab.	Rheumatoid arthritis [FA20]	[20]
Rilonacept	DMGLUQS	Moderate	Additive immunosuppressive effects by the combination of Mitomycin and Rilonacept.	Rheumatoid arthritis [FA20]	[20]
Golimumab	DMHZV7X	Major	Additive immunosuppressive effects by the combination of Mitomycin and Golimumab.	Rheumatoid arthritis [FA20]	[21]
Leflunomide	DMR8ONJ	Major	Additive immunosuppressive effects by the combination of Mitomycin and Leflunomide.	Rheumatoid arthritis [FA20]	[12]
Anthrax vaccine	DM9GSWY	Moderate	Antagonize the effect of Mitomycin when combined with Anthrax vaccine.	Sepsis [1G40-1G41]	[22]
Fostamatinib	DM6AUHV	Moderate	Decreased clearance of Mitomycin due to the transporter inhibition by Fostamatinib.	Thrombocytopenia [3B64]	[23]
Azathioprine	DMMZSXQ	Moderate	Additive immunosuppressive effects by the combination of Mitomycin and Azathioprine.	Transplant rejection [NE84]	[16]
Cinoxacin	DM4EWNS	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Cinoxacin.	Urinary tract infection [GC08]	[11]
Nalidixic acid	DMRM0JV	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Nalidixic acid.	Urinary tract infection [GC08]	[11]
Enoxacin	DMYTE6L	Minor	Decreased absorption of Mitomycin due to intestinal mucosa variation caused by Enoxacin.	Urinary tract infection [GC08]	[11]
Ganciclovir	DM1MBYQ	Moderate	Increased risk of nephrotoxicity by the combination of Mitomycin and Ganciclovir.	Virus infection [1A24-1D9Z]	[16]
Valganciclovir	DMS2IUH	Moderate	Increased risk of nephrotoxicity by the combination of Mitomycin and Valganciclovir.	Virus infection [1A24-1D9Z]	[16]

Drug Inactive Ingredient(s) (DIG) and Formulation(s) of This Drug

DIG

DIG Name	DIG ID	PubChem CID	Functional Classification
Mannitol	E00103	6251	Diluent; Flavoring agent; Lyophilization aid; Plasticizing agent; Tonicity agent
Hypromellose	E00634	Not Available	Coating agent
Polyethylene glycol 4000	E00654	Not Available	Coating agent; Diluent; Ointment base; Plasticizing agent; Solvent; Suppository base; lubricant
Water	E00035	962	Solvent
Hydroxyethyl-beta-cyclodextrin	E00631	Not Available	Other agent

Pharmaceutical Formulation

Formulation Name	Drug Dosage	Dosage Form	Route
Mitomycin 40mg/vial powder	40mg/vial	Powder	Pyelocalyceal
Mitomycin 0.2mg/vial For solution	0.2mg/vial	For Solution	Topical
Mitomycin 5mg/vial injectable	5mg/vial	Injectable	Injection

Jump to Detail Pharmaceutical Formulation Page of This Drug

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7089).
• [2] Mitomycin FDA Label
• [3] Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
• [4] Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds
• [5] Assessment of cell viability, lipid peroxidation and quantification of DNA fragmentation after the treatment of anticancerous drug mitomycin C and ... Exp Toxicol Pathol. 2010 Sep;62(5):503-8.
• [6] In vivo expansion of MDR1-transduced cells accompanied by a post-transplantation chemotherapy regimen with mitomycin C and methotrexate. J Gene Med. 2010 Jul;12(7):596-603.
• [7] Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations. Int J Cancer. 2006 Apr 1;118(7):1699-712. doi: 10.1002/ijc.21570.
• [8] Genomic and proteomic profiling of responses to toxic metals in human lung cells. Environ Health Perspect. 2003 May;111(6):825-35.
• [9] Human aldehyde dehydrogenase 3A1 inhibits proliferation and promotes survival of human corneal epithelial cells. J Biol Chem. 2005 Jul 29;280(30):27998-8006. doi: 10.1074/jbc.M503698200. Epub 2005 May 19.
• [10] Cerner Multum, Inc. "UK Summary of Product Characteristics.".
• [11] Johnson EJ, MacGowan AP, Potter MN, et al "Reduced absorption of oral ciprofloxacin after chemotherapy for haematological malignancy." J Antimicrob Chemother 25 (1990): 837-42. [PMID: 2373666]
• [12] Product Information. Arava (leflunomide). Hoechst Marion-Roussel Inc, Kansas City, MO.
• [13] Product Information. Prolia (denosumab). Amgen USA, Thousand Oaks, CA.
• [14] Bennett CL, Nebeker JR, Samore MH, et al "The Research on Adverse Drug Events and Reports (RADAR) project." JAMA 293 (2005): 2131-40. [PMID: 15870417]
• [15] Product Information. Vumerity (diroximel fumarate). Alkermes, Inc, Cambridge, MA.
• [16] Cerner Multum, Inc. "Australian Product Information.".
• [17] Product Information. Gilenya (fingolimod). Novartis Pharmaceuticals, East Hanover, NJ.
• [18] Product Information. Ocrevus (ocrelizumab). Genentech, South San Francisco, CA.
• [19] Product Information. Synribo (omacetaxine). Teva Pharmaceuticals USA, North Wales, PA.
• [20] Product Information. Arcalyst (rilonacept). Regeneron Pharmaceuticals Inc, Tarrytown, NY.
• [21] Product Information. Cimzia (certolizumab). UCB Pharma Inc, Smyrna, GA.
• [22] CDC. Centers for Disease Control and Prevention/ "Recommendations of the advisory committtee on immunization practices (ACIP): use of vaccines and immune globulins in persons with altered immunocompetence." MMWR Morb Mortal Wkly Rep 42(RR-04) (1993): 1-18. [PMID: 20300058]
• [23] Product Information. Tavalisse (fostamatinib). Rigel Pharmaceuticals, South San Francisco, CA.