Details of the Drug Combinations

General Information of This Drug (ID: DM3KJBC)

• Drug Name: Epinephrine (DM3KJBC)
• Synonyms: ADROP; Adnephrine; Adrenal; Adrenalin; Adrenalina; Adrenaline; Adrenalinum; Adrenamine; Adrenan; Adrenapax; Adrenasol; Adrenatrate; Adrenine; Adrenodis; Adrenohorma; Adrenosan; Adrenutol; Adrin; Adrine; Antiasthmatique; Asthmanefrin; Astmahalin; Astminhal; Balmadren; Bernarenin; Biorenine; Bosmin; Brevirenin; Bronkaid; Chelafrin; Corisol; Drenamist; Dylephrin; Epifrin; Epiglaufrin; Epinefrin; Epinefrina; Epinephran; Epinephrin; Epinephrinum; Epipen; Epirenamine; Epirenan; Epirenin; Epitrate; Eppy; Esphygmogenina; Exadrin; Glaucon; Glaucosan; Glauposine; Glycirenan; Haemostasin; Haemostatin; Hektalin; Hemisine; Hemostasin; Hemostatin; Hypernephrin; Hyporenin; IOP; Intranefrin; Iontocaine; Isoptoepinal; Kidoline; Levoadrenaline; Levoepinephrine; Levorenen; Levorenin; Levorenine; Lyophrin; Metanephrin; Methylaminoethanolcatechol; Methylarterenol; Micronefrin; Micronephrine; Mucidrina; Myosthenine; Mytrate; Nephridine; Nieraline; Paranephrin; Primatene; Racepinephrine; Renagladin; Renaglandin; Renaglandulin; Renaleptine; Renalina; Renoform; Renostypricin; Renostypticin; Renostyptin; Scurenaline; Septocaine; Simplene; Sindrenina; Soladren; Sphygmogenin; Stryptirenal; Styptirenal; Supracapsulin; Supradin; Supranefran; Supranephrane; Supranephrine; Supranol; Suprarenaline; Suprarenin; Suprel; Surenine; Surrenine; Susphrine; Takamina; Takamine; Tokamina; Tonogen; Twinject; Vaponefrin; Vasoconstrictine; Vasoconstrictor; Vasodrine; Vasoton; Vasotonin; ADR ADRENALINE; Adrenalin in Oil; Adrenalina [DCIT]; Asmatane Mist; Asthma meter mist; Asthmahaler Mist; Bronkaid Mist; Bronkaid Suspension Mist; Bupivacaine Hcl and Epinephrine; Citanest Forte; EPI E Z PEN JR; EPIPEN E Z PEN; EPIPEN JR; Epi EZ Pen Jr; Epinefrin [Czech]; Epinephrine hydrochloride; Epipen EZ Pen; Primatene Mist; Racemic Epinephrine; Sympathin I; Adrenalin (TN); Adrenalin-Medihaler; Adrenaline (JP15); Adrenaline/Epinephrine; Ana-Guard; Asthma-nefrin; D-Adrenaline; D-Epifrin; D-Epinephrine; Dyspne-Inhal; Epinefrina [INN-Spanish]; Epinephrine (USP); Epinephrinum [INN-Latin]; Epipen (TN); Epipen Auto-Injector; Epipen Jr.; L-Adrenalin; L-Adrenaline; L-Adrenaline Base; L-Epinehphrine; L-Epinephine; L-Epirenamine; L-Methylaminoethanolcatechol; L-epinephrine; Levo-Methylaminoethanolcatechol; Medihaler-Epi; R-Adrenaline; Sus-Phrine; Twinject 0.15; Twinject 0.3; Twinject 0.30; Epinephrine (USP/INN); Epinephrine [USAN:INN:JAN]; Epipen Jr. Auto-Injector; L-Epinephrine (synthetic); SUS-PHRINE SULFITE-FREE; R-(-)-Epinephrine; L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol; (-)-(R)-Epinephrine; (-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol; (-)-Adrenalin; (-)-Adrenaline; (-)-R-Epinephrine; (R)-(-)-Adnephrine; (R)-(-)-Adrenaline; (R)-(-)-Epinephrine; (R)-(-)-Epirenamine; (R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol; (R)-Adrenaline; (R)-Epinephrine; 1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol; 1-Adrenalin; 1-Epinephrine; 4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol; 4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol; 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol; 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol

Indication

Acute asthma; ICD 11: CA23; Status: Approved [1]; Allergy; ICD 11: 4A80-4A85; Status: Approved [2]; Anaphylaxis; ICD 11: N.A.; Status: Approved [1]; Bronchiectasis; ICD 11: CA24; Status: Approved [1]; Bronchitis; ICD 11: CA20; Status: Approved [1]; Periodontitis; ICD 11: DA0C; Status: Approved [1]; Pulmonary emphysema; ICD 11: CA21.Z; Status: Approved [1]; Severe asthma; ICD 11: CA23; Status: Approved [1]; Asthma; ICD 11: CA23; Status: Investigative [1]

• Therapeutic Class: Vasoconstrictor Agents
• Drug Type: Small molecular drug

List of Combinatorial Drugs (CBD) Containing This Drug

170 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Epinephrine	DCW9862	1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Abacavir + Epinephrine	DC0DD03	Abacavir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Acamprosate + Epinephrine	DC4HRFQ	Acamprosate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Acetazolamide + Epinephrine	DCGG3NA	Acetazolamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Amiloride + Epinephrine	DCSJ323	Amiloride	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Artemisinin + Epinephrine	DC0FKRN	Artemisinin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Asenapine + Epinephrine	DC4VUTY	Asenapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Benserazide + Epinephrine	DC3CB8H	Benserazide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
BHV-0223 + Epinephrine	DC9O15D	BHV-0223	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Brincidofovir + Epinephrine	DC6TGD4	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Bumetanide + Epinephrine	DCWQKQ3	Bumetanide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Busulfan + Epinephrine	DC9QZ5N	Busulfan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cefmenoxime + Epinephrine	DCDQ8KQ	Cefmenoxime	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cerivastatin + Epinephrine	DCPPUSH	Cerivastatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cilastatin + Epinephrine	DC7YIPS	Cilastatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cilostazol + Epinephrine	DC5ZXBW	Cilostazol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cinacalcet + Epinephrine	DCOA9YT	Cinacalcet	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Citalopram + Epinephrine	DC7FRR8	Citalopram	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Clindamycin + Epinephrine	DCS79VQ	Clindamycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Crotamiton + Epinephrine	DCZ3U1T	Crotamiton	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cytarabine + Epinephrine	DCSV8HK	Cytarabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Desoxycorticosterone pivalate + Epinephrine	DCK1N3P	Desoxycorticosterone pivalate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dichlorphenamide + Epinephrine	DC2TSBA	Dichlorphenamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Diphenidol + Epinephrine	DCYCPLU	Diphenidol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Docetaxel + Epinephrine	DC0H4OU	Docetaxel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Doxorubicin + Epinephrine	DC8PX6M	Doxorubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Endoxifen + Epinephrine	DCF9F7D	Endoxifen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Entacapone + Epinephrine	DCDPN1R	Entacapone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Aprepitant	DC8JRP8	Aprepitant	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Lefaxin	DCAFEYH	Lefaxin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Pentostatin	DC28MY3	Pentostatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Mebutamate	DCWVI24	Mebutamate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Picoplatin	DCER8VX	Picoplatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Baclofen	DCAV70W	Baclofen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Bepridil	DCLUIYX	Bepridil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Triiodothyronine	DCN3F4P	Triiodothyronine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Aliskiren	DCJC8GI	Aliskiren	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Diethylcarbamazine	DCW6N6B	Diethylcarbamazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Lumefantrine	DCT81JT	Lumefantrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Kanamycin	DCJGTRN	Kanamycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Citalopram	DCDGGFL	Citalopram	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Imipramine	DCF04R4	Imipramine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Terazosin	DCIN376	Terazosin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Furazolidone	DCHZH1L	Furazolidone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Chlorphenesin	DCINW4D	Chlorphenesin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + GYKI-52466	DC87N9I	GYKI-52466	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Tacrine	DC447TZ	Tacrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Panobinostat	DCMELRN	Panobinostat	Diffuse intrinsic pontine glioma (Cell Line: DIPG25)	[3]
Epinephrine + Dihydroergotamine	DCOL4GE	Dihydroergotamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Repaglinide	DCDOPRR	Repaglinide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Vinblastine	DC8680F	Vinblastine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Pazopanib HCl	DCFF0J7	Pazopanib HCl	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Fomepizole	DCXUQZP	Fomepizole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Ezetimibe	DCKV1TN	Ezetimibe	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Acitretin	DCL7YCX	Acitretin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Dronedarone	DCLALVW	Dronedarone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Rifampin	DCNGW4S	Rifampin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Palonosetron	DCAG0NE	Palonosetron	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Isosorbide dinitrate	DCO1QDI	Isosorbide dinitrate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Emetine	DCA522Q	Emetine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Ursodeoxycholic acid	DCW0V6A	Ursodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Carglumic acid	DCBSK49	Carglumic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Doxapram	DC1EXM5	Doxapram	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Chlorzoxazone	DCW30AZ	Chlorzoxazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Memantine	DC27FXI	Memantine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Metformin	DCSQ2YC	Metformin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Methoxsalen	DC6Q8BN	Methoxsalen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Ginsenoside Rb1	DC8Q1XX	Ginsenoside Rb1	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Phensuximide	DCCZKK9	Phensuximide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + VR-776	DCM4XNX	VR-776	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Ciprofibrate	DCOS4AK	Ciprofibrate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Naringenin	DCJLU0T	Naringenin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Clopidogrel	DC6WYAE	Clopidogrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Diphenidol	DCPJA03	Diphenidol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Pentamidine	DCLDEEY	Pentamidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Bosentan	DCQWWM1	Bosentan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Sulfapyridine	DC5Y1UF	Sulfapyridine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Triflupromazine	DC2RO7L	Triflupromazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Niclosamide	DC8UKQ2	Niclosamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Eflornithine	DCU7CWX	Eflornithine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Tiagabine	DCRB8U7	Tiagabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Ibutilide	DCNH405	Ibutilide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Diazoxide	DCAES15	Diazoxide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Pargyline	DCRM11B	Pargyline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Idarubicin	DCBFI80	Idarubicin	Glioblastoma? (Cell Line: T98G)	[3]
Epinephrine + Probenecid	DCNHQRO	Probenecid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Darunavir	DC9LJ0Z	Darunavir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Pramipexole	DC1BG9Y	Pramipexole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Moricizine	DC2C5TM	Moricizine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Topotecan	DC8JFE9	Topotecan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Dopamine	DCE14KI	Dopamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Enalaprilat	DCLPU0G	Enalaprilat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Oxyphenbutazone	DC3XVCS	Oxyphenbutazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Eptifibatide	DCSINHW	Eptifibatide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Acetohexamide	DCM472V	Acetohexamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Ethambutol	DC9QORN	Ethambutol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Leflunomide	DCWNTUW	Leflunomide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Theophylline	DC0LKRR	Theophylline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Spironolactone	DC0BPMF	Spironolactone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Cisatracurium	DCB3KIJ	Cisatracurium	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Lacosamide	DCP2OJ4	Lacosamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Iloprost	DC3KP5N	Iloprost	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Zileuton	DCILDXH	Zileuton	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Silver sulfadiazine	DCZ0O0J	Silver sulfadiazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Testolactone	DCJ414H	Testolactone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Sumatriptan	DCMV1NF	Sumatriptan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Olmesartan medoxomil	DCZU571	Olmesartan medoxomil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + PMID28870136-Compound-43	DCKVMCV	PMID28870136-Compound-43	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Estramustine	DCSVX84	Estramustine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Hydroxychloroquine	DC5EO1O	Hydroxychloroquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Atovaquone	DC7951C	Atovaquone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + ML323	DCAIVR4	ML323	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + AS-1949490	DCSAUBN	AS-1949490	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Nitrosoglutathione	DCM2CM2	Nitrosoglutathione	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Etomidate	DCWVKNT	Etomidate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + L-165041	DC1Q76F	L-165041	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Etonogestrel + Epinephrine	DCJSOM2	Etonogestrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Everolimus + Epinephrine	DC0RHLU	Everolimus	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Fibrates + Epinephrine	DCITNMN	Fibrates	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Flavonoid derivative 1 + Epinephrine	DC2UM0Z	Flavonoid derivative 1	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
FORMESTANE + Epinephrine	DCA3RY8	FORMESTANE	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Galantamine + Epinephrine	DCYLUAQ	Galantamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
GSK2194069 + Epinephrine	DCQI1WC	GSK2194069	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Guanfacine + Epinephrine	DCGXJU5	Guanfacine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Hydralazine + Epinephrine	DCMFUCL	Hydralazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Imatinib + Epinephrine	DCXU1D4	Imatinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
IT-141 + Epinephrine	DCF2SLS	IT-141	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Linagliptin + Epinephrine	DCXN4ZB	Linagliptin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Loperamide + Epinephrine	DC55MUO	Loperamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Lubiprostone + Epinephrine	DCDFIL0	Lubiprostone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Maraviroc + Epinephrine	DCGTETW	Maraviroc	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Mebendazole + Epinephrine	DCJCV0D	Mebendazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Mebutamate + Epinephrine	DCCXDAG	Mebutamate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Mephenytoin + Epinephrine	DCE73XS	Mephenytoin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Mesalazine + Epinephrine	DCCWVGW	Mesalazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Metaxalone + Epinephrine	DCQNZ19	Metaxalone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methocarbamol + Epinephrine	DC10RCP	Methocarbamol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methotrexate + Epinephrine	DCGBT6I	Methotrexate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Metyrosine + Epinephrine	DC3D82B	Metyrosine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Miglustat + Epinephrine	DCXUCDL	Miglustat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Nabilone + Epinephrine	DCHSREQ	Nabilone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Norcisapride + Epinephrine	DCH38W2	Norcisapride	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Oxandrolone + Epinephrine	DCLY7X8	Oxandrolone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pentamidine + Epinephrine	DCPFDX9	Pentamidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pepstatin + Epinephrine	DCJLFU2	Pepstatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
PF-02545920 + Epinephrine	DCPGMGG	PF-02545920	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
PFK-158 + Epinephrine	DC84DDR	PFK-158	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
PHA-739358 + Epinephrine	DCMEKF0	PHA-739358	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Phenprocoumon + Epinephrine	DCO0HH6	Phenprocoumon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pizotyline + Epinephrine	DCGFI6O	Pizotyline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pomalidomide + Epinephrine	DC0918Q	Pomalidomide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pramipexole + Epinephrine	DC24W39	Pramipexole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Probenecid + Epinephrine	DCITGRE	Probenecid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Ramelteon + Epinephrine	DCPW3LF	Ramelteon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Ribavirin-TP + Epinephrine	DCUZVNV	Ribavirin-TP	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Rufinamide + Epinephrine	DCQSDVA	Rufinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Sivelestat + Epinephrine	DCY2SMQ	Sivelestat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Sorafenib + Epinephrine	DCYZDIE	Sorafenib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Sumatriptan + Epinephrine	DC2XFVH	Sumatriptan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tacrolimus + Epinephrine	DCZAX1F	Tacrolimus	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tamoxifen + Epinephrine	DCGES3D	Tamoxifen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Teriflunomide + Epinephrine	DC0UOWO	Teriflunomide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tindamax + Epinephrine	DCITH2T	Tindamax	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tolazoline + Epinephrine	DCCD1BG	Tolazoline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Triflupromazine + Epinephrine	DCHXHN6	Triflupromazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trimethobenzamide + Epinephrine	DCV0ZX3	Trimethobenzamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tropisetron + Epinephrine	DCVC1W4	Tropisetron	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Valproic Acid + Epinephrine	DCR0G1E	Valproic Acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
WAY-100635 + Epinephrine	DCB7NOS	WAY-100635	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Zaleplon + Epinephrine	DCSPFUO	Zaleplon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]

22 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Epinephrine + Phenylephrine	DC1U11I	Phenylephrine	Intracranial Aneurysm	[4]
Epinephrine + Levobupivacaine	DCD8QCR	Levobupivacaine	Pain, Postoperative	[5]
Epinephrine + Ropivacaine	DCKN0JC	Ropivacaine	Femoral Neck Fractures	[6]
Epinephrine + Ropivacaine	DCS886H	Ropivacaine	Traumatic Femur Fracture	[7]
Epinephrine + Indomethacin	DCTPM8K	Indomethacin	Post-ERCP Acute Pancreatitis	[8]
Epinephrine + Tranexamic acid	DCUJ71Z	Tranexamic acid	Knee Prosthesis	[9]
Epinephrine + Betamethasone	DCZPOO1	Betamethasone	Children	[10]
Naloxone + Epinephrine	DCTPGUA	Naloxone	Diabetes Mellitus	[11]
Epinephrine + Lidocaine	DCC0ZTM	Lidocaine	Irreversible Pulpitis	[12]
Epinephrine + Articaine	DCN6P7U	Articaine	Irreversible Pulpitis	[12]
Epinephrine + Dobutamine	DC4YI3F	Dobutamine	Oral Cancer	[13]
Epinephrine + Dexamethasone	DC53R25	Dexamethasone	Postoperative Pain	[14]
Epinephrine + Ketorolac	DC5GTK4	Ketorolac	Osteoarthritis of the Knee	[15]
Epinephrine + Ketorolac	DC5KV9L	Ketorolac	Osteoarthritis	[16]
Epinephrine + Propofol	DCCS6IS	Propofol	Hemodynamic Instability	[17]
Epinephrine + Clonidine	DCD09A2	Clonidine	Total Hip and Knee Arthroplasty	[18]
Epinephrine + Dexmedetomidine	DCWUBUH	Dexmedetomidine	Hemodynamic Instability	[17]
Epinephrine + Clonidine	DC0MOL2	Clonidine	Hip Dysplasia	[19]
Epinephrine + Ketorolac	DCBOIVX	Ketorolac	Pain	[20]
Epinephrine + Tranexamic acid	DC612YU	Tranexamic acid	Pain, Postoperative	[21]
Epinephrine + Norepinephrine	DCCG2C2	Norepinephrine	Shock	[22]
Epinephrine + Lidocaine	DCNLSFT	Lidocaine	Surgery	[23]

References

• [1] Epinephrine FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 509).
• [3] Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
• [4] ClinicalTrials.gov (NCT02701582) Goal-Directed Intraoperative Fluid Management Using FloTrac Monitoring in High-Risk Neurosurgical Patients
• [5] ClinicalTrials.gov (NCT04020133) the Role of Popliteal Plexus Block in Pain Management After Anterior Cruciate Ligament Reconstruction.
• [6] ClinicalTrials.gov (NCT02585011) Effect of Local Infiltration Anesthesia With Ropivacaine on Postoperative Pain After Hip Hemiarthroplasty
• [7] ClinicalTrials.gov (NCT01759407) Femoral Nerve Block for Femur Fracture Repair in Pediatrics
• [8] ClinicalTrials.gov (NCT02116309) Randomized Trial of Rectal Indomethacin and Papillary Spray of Epinephrine Versus Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
• [9] ClinicalTrials.gov (NCT02319915) Evaluation of the Pharmacokinetic Profile of Tranexamic Acid, After Injection in a Knee Neo-articulation.
• [10] ClinicalTrials.gov (NCT02586961) Nebulized Adrenalin and Oral Betamethasone in Children With Bronchiolitis Attending Pediatric Emergencies.
• [11] ClinicalTrials.gov (NCT00678145) Mechanisms of Hypoglycemia Associated Autonomic Failure
• [12] ClinicalTrials.gov (NCT02807298) 4% Articaine and 2% Lidocaine by Intraligamentary Technique in Irreversible Pulpitis
• [13] ClinicalTrials.gov (NCT01418118) Assessment of the Effects of Pressors on Graft Blood Flow After Free Tissue Transfer Surgery
• [14] ClinicalTrials.gov (NCT03057015) Addition of Clonidine to Ropivacaine in Adductor Canal Block
• [15] ClinicalTrials.gov (NCT00562627) Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty
• [16] ClinicalTrials.gov (NCT02658149) Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty
• [17] ClinicalTrials.gov (NCT02464722) Comparision Between Hemodynamic Response of Dexmedetomidine and Remifentanil on Anesthesia in Endoscopic Sinus Surgery
• [18] ClinicalTrials.gov (NCT02543801) A Clinical Trial of Two Periarticular Multimodal Drug Injections in Total Hip and Knee Arthroplasty
• [19] ClinicalTrials.gov (NCT02365961) Hip Scope Fascia-iliaca (FI) Block Study
• [20] ClinicalTrials.gov (NCT04141319) Effects of Pre-emptive Scalp Infiltration With Ketorolac and Ropivacaine for Post-craniotomy Pain
• [21] ClinicalTrials.gov (NCT01964781) The Effect of Topical Administration of Common Drugs on Postoperative Bleeding and Pain
• [22] ClinicalTrials.gov (NCT02118467) Vasoactive Drugs in Intensive Care Unit
• [23] ClinicalTrials.gov (NCT01964586) Comparison of Preincisional Infiltrated Dexmedetomidine and Lidocaine Plus Adrenaline for Nasal Sephoplasty Surgery.