General Information of This Drug (ID: DMS6UOE)

Drug Name
Azithromycin   DMS6UOE
Synonyms
azithromycin; Zithromax; 83905-01-5; Sumamed; Zitromax; Zmax; Azithromycinum; Azithromycine; Hemomycin; Azitrocin; Azasite; Azenil; Zitrotek; Misultina; Zithrax; Azitromax; Mixoterin; Setron; Aziwok; Zitrim; Tromix; Aztrin; Zifin; Tobil; Zmas; Zeto; Azithromycinum [Latin]; Azithromycine [French]; Zithromax IV; AZITHROMYCIN DIHYDRATE; CP-62993; Z-Pak; Aritromicina [Spanish]; CP 62993; UNII-J2KLZ20U1M; DRG-0104; C38H72N2O12; CCRIS 1961; HSDB 7205; Azithromycin (anhydrous); BRN 5387583; J2KLZ20U1M; Azythromycin; CHEBI:2955; Azithromycin (AIDS Initiative; Azithromycin
Indication
Disease Entry ICD 11 Status REF
Acute gonococcal cervicitis N.A. Approved [1]
Bronchitis CA20 Approved [2]
Chancroid N.A. Approved [1]
Mycoplasma pneumoniae pneumonia N.A. Approved [1]
Staphylococcus aureus infection N.A. Approved [1]
Streptococcal pneumonia N.A. Approved [1]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 3 [3]
Pneumonia caused by chlamydia N.A. Investigative [1]
⏷ Show the Full List of Indication(s)
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Azithromycin + Idarubicin DC81WOB Idarubicin Glioblastoma? (Cell Line: T98G) [4]
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1 Discontinued Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Azithromycin + Chloroquine DCPBGEO Chloroquine Bacterial infection [5]
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46 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Ampicillin + Azithromycin DCOTKBU Ampicillin Preterm Pre-labor Rupture of Membranes [6]
Ampicillin + Azithromycin DCTXX6Y Ampicillin Preterm Pre-labor Rupture of Membranes [6]
Azithromycin + Chloroquine DCHVLZW Chloroquine Plasmodium Falciparum Infection [7]
Azithromycin + Colchicine DCN9B8N Colchicine Pharmacokinetics [8]
Azithromycin + Cefixime DCOUV8I Cefixime Vaginitis Bacterial [9]
Azithromycin + Chloroquine DCXXX1G Chloroquine Malaria Prophylaxis [10]
Cefazolin + Azithromycin DCJH5NV Cefazolin Endometritis [11]
Cefazolin + Azithromycin DC2U21G Cefazolin Obesity [12]
Cefpodoxime + Azithromycin DCYXAKJ Cefpodoxime Microbiota [13]
Ceftriaxone + Azithromycin DC54EZM Ceftriaxone Chlamydia [14]
Fosmidomycin + Azithromycin DCY4WQ6 Fosmidomycin Malaria [15]
Gemifloxacin + Azithromycin DC0IXSC Gemifloxacin Gonorrhoea [16]
Gentamicin + Azithromycin DCQ7OW0 Gentamicin Gonorrhoea [16]
Levofloxacin + Azithromycin DC2K64F Levofloxacin Acute Watery Diarrhea [17]
Methylprednisolone + Azithromycin DCQJ9NF Methylprednisolone Idiopathic Pulmonary Fibrosis [18]
Oseltamivir + Azithromycin DCJCHFA Oseltamivir COVID [19]
Prednisolone + Azithromycin DC7JDMN Prednisolone Asthma [20]
Rifabutin + Azithromycin DCMXYGQ Rifabutin Mycobacterium Avium Complex [21]
Tindamax + Azithromycin DCZLQOK Tindamax Urethritis [22]
Azithromycin + Hydroxychloroquine DC6CLQX Hydroxychloroquine Virus Diseases [23]
Azithromycin + Cefoxitin DC9ISIN Cefoxitin Endometritis [24]
Azithromycin + Metronidazole DCBLMVZ Metronidazole Crohn Disease [25]
Azithromycin + Mefloquine DCMXADR Mefloquine Coronavirus Disease 2019 (COVID-19) [26]
Azithromycin + Atovaquone DCTKUJS Atovaquone Coronavirus Disease 2019 (COVID-19) [27]
Ethambutol + Azithromycin DC3CX2X Ethambutol Mycobacterium Avium Complex [28]
Lopinavir + Azithromycin DCHOB2C Lopinavir COVID [29]
Tocilizumab + Azithromycin DCV09V7 Tocilizumab Coronavirus Disease 2019 (COVID-19) [26]
Tocilizumab + Azithromycin DCXKIA6 Tocilizumab Coronavirus Disease 2019 (COVID-19) [26]
Ampicillin + Azithromycin DC79T9J Ampicillin Preterm Premature Rupture of Membranes (PPROM) [30]
Azithromycin + Hydroxychloroquine DC8Y9J6 Hydroxychloroquine COVID19 [31]
Azithromycin + Tetracycline DCIYFBD Tetracycline Trachoma [32]
Azithromycin + Albendazole DCTSVGW Albendazole Moderate Acute Malnutrition [33]
Azithromycin + Hydroxychloroquine DC5HNLI Hydroxychloroquine Coronavirus Disease 2019 (COVID-19) [34]
Azithromycin + Hydroxychloroquine DCHHDRF Hydroxychloroquine Coronavirus Disease 2019 (COVID-19) [35]
Ceftriaxone + Azithromycin DCO5GSI Ceftriaxone Uncomplicated Urogenital Gonorrhea [36]
Doxycycline + Azithromycin DCEB9X3 Doxycycline COVID 19 [37]
Favipiravir + Azithromycin DCRBMF4 Favipiravir Infectious Disease [38]
Oseltamivir + Azithromycin DC1NHUI Oseltamivir COVID 19 [39]
Oseltamivir + Azithromycin DCT9TTY Oseltamivir COVID 19 [39]
Azithromycin + Albendazole DCI4GCM Albendazole Helminth Infection [40]
Azithromycin + Tobramycin DCKBV2P Tobramycin Cystic Fibrosis [41]
Azithromycin + Loperamide DCQNL2R Loperamide Diarrhoea;Acute [42]
Cefotaxime + Azithromycin DCZ8GI2 Cefotaxime Cirrhosis [43]
Ceftriaxone + Azithromycin DCIWS8I Ceftriaxone Community-Acquired Pneumonia (CAP) [44]
Ivermectin + Azithromycin DCCFALE Ivermectin Scabies [45]
Zinc Sulfate + Azithromycin DCDHS4Z Zinc Sulfate COVID-19 [46]
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⏷ Show the Full List of 46 DrugCom(s)

References

1 Azithromycin FDA Label
2 FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 065511.
3 ClinicalTrials.gov (NCT04332107) Azithromycin for COVID-19 Treatment in Outpatients Nationwide. U.S. National Institutes of Health.
4 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
5 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019101)
6 ClinicalTrials.gov (NCT04202380) Azithromycin for Preterm Pre-labor Rupture of Membranes
7 ClinicalTrials.gov (NCT00379821) Chloroquine Alone or in Combination for Malaria in Children in Malawi
8 ClinicalTrials.gov (NCT00983294) Drug-Drug Interaction Study of Colchicine and Azithromycin
9 ClinicalTrials.gov (NCT01072136) Empiric Therapy of Mucopurulent Cervicitis (MPC)
10 ClinicalTrials.gov (NCT01100060) A Phase 1 Study To Estimate The Relative Bioavailability Of Co-Administered Formulations Of Azithromycin Microsphere And Chloroquine Test Formulation Compared With Co-Administered Immediate Release Individual Azithromycin And Chloroquine Tablets In Healthy Adult Subjects
11 ClinicalTrials.gov (NCT01721616) Comparison Study of Cefazolin Versus Cefazolin Plus Azithromycin Prophylaxis in Post-Cesarean Endometritis
12 ClinicalTrials.gov (NCT03801252) Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term
13 ClinicalTrials.gov (NCT03098485) Healthy Patients & Effect of Antibiotics
14 ClinicalTrials.gov (NCT01150747) Chlamydia Trachomatis Immunology and Vaccinology Study
15 ClinicalTrials.gov (NCT01464125) Fosmidomycin and Azithromycin for Acute Uncomplicated Plasmodium Falciparum Malaria (P. Malaria) in Adults
16 ClinicalTrials.gov (NCT00926796) Efficacy of Combination Therapies for Gonorrhea Treatment
17 ClinicalTrials.gov (NCT01618591) Trial Evaluating Ambulatory Treatment of Travelers' Diarrhea
18 ClinicalTrials.gov (NCT05842681) Azithromycin in the Management of Patients With Acute Exacerbation of Idiopathic Pulmonary Fibrosis
19 ClinicalTrials.gov (NCT04457609) Administration of Allogenic UC-MSCs as Adjuvant Therapy for Critically-Ill COVID-19 Patients
20 ClinicalTrials.gov (NCT01272635) Treatment of Preschool Children With Upper Respiratory Tract Illnesses Using Azythromycin and Lower Respiratory Tract Symptoms Using Oral Corticosteroids.
21 ClinicalTrials.gov (NCT00598962) Use of Azithromycin and Rifabutin Administered 3 Times Weekly for the Treatment of M. Avium Complex (MAC) Lung Disease
22 ClinicalTrials.gov (NCT00322465) NGU: Doxycycline (Plus or Minus Tinidazole) Versus Azithromycin (Plus or Minus Tinidazole)
23 ClinicalTrials.gov (NCT04322396) Proactive Protection With Azithromycin and hydroxyChloroquine in Hospitalized Patients With COVID-19
24 ClinicalTrials.gov (NCT03960970) Two-drug Antibiotic Prophylaxis in Scheduled Cesarean Deliveries
25 ClinicalTrials.gov (NCT04186247) Personalized AZithromycin/metronidAZole Therapy in Pediatric Crohn's Disease (CD)
26 ClinicalTrials.gov (NCT04347031) An Open Randomized Study of the Effectiveness of Mefloquine for the Treatment of Patients With COVID19. U.S. National Institutes of Health.
27 ClinicalTrials.gov (NCT04339426) Atovaquone and Azithromycin Combination for Confirmed COVID-19 Infection. U.S. National Institutes of Health.
28 ClinicalTrials.gov (NCT03672630) Comparison of Two- Versus Three-antibiotic Therapy for Pulmonary Mycobacterium Avium Complex Disease
29 ClinicalTrials.gov (NCT04459702) A Study of Combination Therapies to Treat COVID-19 Infection
30 ClinicalTrials.gov (NCT03060473) Treatment of ppROM With Erythromycin vs. Azithromycin Trial
31 ClinicalTrials.gov (NCT04328272) Effectiveness of Hydroxychloroquine in Covid-19 Patients
32 ClinicalTrials.gov (NCT02754583) Sanitation, Water, and Instruction in Face-washing for Trachoma I/II
33 ClinicalTrials.gov (NCT03474276) Comparing Several Strategies to Manage Moderate Acute Malnutrition Among Children From 6 to 24 Months Old
34 ClinicalTrials.gov (NCT04321278) Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-CoV2 Virus (Coalition Covid-19 Brasil II). U.S. National Institutes of Health.
35 ClinicalTrials.gov (NCT04371406) Efficacy of Azithromycin-associated Hydroxychloroquine Therapy Given in General Practice in Early-stage Disease in COVID-19 Patients. U.S. National Institutes of Health.
36 ClinicalTrials.gov (NCT02210325) Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea
37 ClinicalTrials.gov (NCT04528927) Evaluation of the Efficacy and Safety of Treatments for Patients Hospitalized for COVID-19 Infection Without Signs of Acute Respiratory Failure, in Tunisia
38 ClinicalTrials.gov (NCT04613271) Efficacy and Safety of Favipiravir in Covid-19 Patients in Indonesia
39 ClinicalTrials.gov (NCT04338698) Hydroxychloroquine, Oseltamivir and Azithromycin for the Treatment of COVID-19 Infection: An RCT
40 ClinicalTrials.gov (NCT03032042) Intestinal Microbiome Post-Azythromycin/Albendazole Treatment
41 ClinicalTrials.gov (NCT02677701) Testing the Effect of Adding Chronic Oral Azithromycin to Inhaled Tobramycin in People With Cystic Fibrosis (CF)
42 ClinicalTrials.gov (NCT05677282) Single Dose Antibiotic Treatment of Acute Watery Diarrhea, Rifaximin Versus Azithromycin, With Loperamide Adjunct
43 ClinicalTrials.gov (NCT01820026) Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis
44 ClinicalTrials.gov (NCT00035347) Intravenous Azithromycin Plus Intravenous Ceftriaxone Followed by Oral Azithromycin With Intravenous Levofloxacin Followed by Oral Levofloxacin for the Treatment of Moderate to Severely Ill Hospitalized Patients With Community Acquired Pneumonia
45 ClinicalTrials.gov (NCT02775617) Azithromycin - Ivermectin Mass Drug Administration for Skin Disease
46 ClinicalTrials.gov (NCT04370782) Hydroxychloroquine and Zinc With Either Azithromycin or Doxycycline for Treatment of COVID-19 in Outpatient Setting