Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMH65Q8)

• Drug Name: acetyl CoA Drug Info
• Synonyms: acetyl coenzyme A; S-acetyl coenzyme A; acetylCoA; acetyl-CoA

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 444493
  ChEBI ID: CHEBI:15351
  CAS Number: CAS 72-89-9
  TTD Drug ID: DMH65Q8
  INTEDE Drug ID: DR2037

Molecule-Related Drug Atlas

Drug(s) Affected By Arylamine N-acetyltransferase 1 (NAT1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Procainamide	DMNMXR8	Ventricular arrhythmias	BC71	Approved	[6]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[7]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[8]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[6]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[9]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[9]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[10]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[11]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[6]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[12]

Drug(s) Affected By Amyloid-beta precursor protein (APP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[13]
Selenium	DM25CGV	N. A.	N. A.	Approved	[14]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[15]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[16]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[17]
Penicillamine	DM40EF6	Cystinuria	5C60.2	Approved	[18]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[19]
Isoniazid	DM5JVS3	Latent tuberculosis infection		Approved	[20]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[21]
Aluminium	DM6ECN9	Hyperhidrosis	EE00	Approved	[22]

Drug(s) Affected By Chimeric ERCC6-PGBD3 protein (ERCC6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[23]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[11]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[24]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[25]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[26]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[25]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[27]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[28]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[29]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[30]

Molecular Interaction Atlas of This Drug

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Cysteinyl-conjugate N-acetyltransferase (NAT8) Main DME	DEA742Z	NAT8_HUMAN	Substrate	[2]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Amyloid-beta precursor protein (APP)	OTKFD7R4	A4_HUMAN	Protein Interaction/Cellular Processes	[3]
Arylamine N-acetyltransferase 1 (NAT1)	OTCCNQ3H	ARY1_HUMAN	Protein Interaction/Cellular Processes	[4]
Chimeric ERCC6-PGBD3 protein (ERCC6)	OT2QZKSF	ERPG3_HUMAN	Regulation of Drug Effects	[5]

References

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