Details of the Drug Reposition

General Information of This Drug (ID: DMF28YC)

Drug Name
Atorvastatin   DMF28YC
Synonyms
Atogal; Atorlip; Atorpic; Atorvastatina; Atorvastatine; Atorvastatinium; Atrovastin; Cardyl; Faboxim; Lipotropic; Lipovastatinklonal; Liprimar; Lowden; Sincol; Sortis; Sotis; Torvacard; Torvast; Totalip; Tozalip; Tulip; Vastina; Xanator; Xarator; Xavator; Zurinel; Atorvastatin (INN); Atorvastatin [INN:BAN]; Lipitor (TN); Lipitor(TM); Sortis (TN); (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid; (3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid; (R-(R*,R*))-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrole-1-heptanoic acid; (betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid; 7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]-3,5-DIHYDROXY-HEPTANOIC ACID
Therapeutic Class
Anticholesteremic Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
11 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Hyperlipidemia, familial combined, LPL related DISL1CE3 N.A. Approved [1]
Coronary atherosclerosis DISKNDYU N.A. Approved [1]
Inflammation DISJUQ5T 1A00-CA43.1 Approved [1]
Type-1/2 diabetes DISIUHAP 5A10-5A11 Approved [1]
Non-insulin dependent diabetes DISK1O5Z 5A11 Approved [1]
Hyperlipidemia DIS61J3S 5C80.Z Approved [2]
Hypertriglyceridemia DIS7SN6U 5C80.1 Approved [1]
Angina pectoris DISCLMC4 BA40 Approved [1]
Acute coronary syndrome DIS7DYEW BA41 Approved [1]
Arteriosclerosis DISK5QGC BD40 Approved [1]
Psoriasis DIS59VMN EA90 Approved [1]
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⏷ Show the Full List of 11 Indications(s)
1 Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Coronavirus Disease 2019 (COVID-19) DISM7GNX 1D6Y Phase 2 [3]
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1 Discontinued in Phase 3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
High blood pressure DISY2OHH BA00 Discontinued in Phase 3 [4]
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2 Investigative Indication(s)
Indication Name Indication ID ICD-11 Status REF
Stroke DISX6UHX 8B20 Investigative [1]
Venous thromboembolism DISUR7CR BD72 Investigative [1]
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References

1 Atorvastatin FDA Label
2 FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 205945.
3 ClinicalTrials.gov (NCT04380402) Atorvastatin in COVID-19. U.S. National Institutes of Health.
4 Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor