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ClinicalTrials.gov (NCT01792284) A Study of LY2605541 in Participants With Type 1 Diabetes Mellitus. U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT02302716) A Study of LY2963016 Compared to LANTUS in Adult Participants With Type 2 Diabetes Mellitus. U.S. National Institutes of Health.
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A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
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Liver carbohydrates metabolism: A new islet-neogenesis associated protein peptide (INGAP-PP) target. Peptides. 2018 Mar;101:44-50.
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034087)
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021813)
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ClinicalTrials.gov (NCT01933256) Study of Subcutaneous Doses of HIP2B in Subjects With Type 2 Diabetes Mellitus Treated With Metformin. U.S. National Institutes of Health.
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024972)
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ClinicalTrials.gov (NCT03095651) Multiple Ascending Dose Study of MK-5160 in Participants With Type 1 and Type 2 Diabetes Mellitus (MK-5160-002). U.S. National Institutes of Health.
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800037853)
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800036594)
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The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. Genet Med. 2022 Aug;24(8):1732-1742. doi: 10.1016/j.gim.2022.04.017. Epub 2022 May 4.
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The Short Version of the Activities-Specific Balance Confidence Scale for Older Adults with Diabetes-Convergent, Discriminant and Concurrent Validity: A Pilot Study.Can J Diabetes. 2017 Jun;41(3):266-272. doi: 10.1016/j.jcjd.2016.10.007. Epub 2017 Mar 3.
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Effects of Honokiol on CYP450 Activity and Transporter mRNA Expression in Type 2 Diabetic Rats.Int J Mol Sci. 2018 Mar 12;19(3):815. doi: 10.3390/ijms19030815.
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ABCG5 and ABCG8 gene polymorphisms in type 2 diabetes mellitus in the Turkish population.Can J Diabetes. 2015 Oct;39(5):405-10. doi: 10.1016/j.jcjd.2015.04.004. Epub 2015 Jun 16.
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Protocatechuic acid ameliorates neurobehavioral deficits via suppression of oxidative damage, inflammation, caspase-3 and acetylcholinesterase activities in diabetic rats.Food Chem Toxicol. 2019 Mar;125:170-181. doi: 10.1016/j.fct.2018.12.040. Epub 2018 Dec 29.
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Lower Concentrations of Circulating Medium and Long-Chain Acylcarnitines Characterize Insulin Resistance in Persons with HIV.AIDS Res Hum Retroviruses. 2018 Jun;34(6):536-543. doi: 10.1089/AID.2017.0314. Epub 2018 May 2.
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A novel association between TGFb1 and ADAMTS4 in coronary artery disease: A new potential mechanism in the progression of atherosclerosis and diabetes.Anatol J Cardiol. 2015 Oct;15(10):823-9. doi: 10.5152/akd.2014.5762. Epub 2014 Oct 31.
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Can pancreatic cancer be detected by adrenomedullin in patients with new-onset diabetes? The PaCANOD cohort study protocol.Tumori. 2018 Aug;104(4):312-314. doi: 10.5301/tj.5000693. Epub 2018 May 8.
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Lentivirusmediated overexpression of CD97/ADGRE5 reverses dysregulated high glucoseinduced endothelial cell migration.Mol Med Rep. 2017 May;15(5):3048-3054. doi: 10.3892/mmr.2017.6417. Epub 2017 Mar 30.
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Different response of ANP secretion to adrenoceptor stimulation in renal hypertensive rat atria.Peptides. 2008 Jul;29(7):1207-15. doi: 10.1016/j.peptides.2008.02.011. Epub 2008 Feb 26.
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Deep sea minerals ameliorate diabetic-induced inflammation via inhibition of TNF signaling pathways.Environ Toxicol. 2020 Apr;35(4):468-477. doi: 10.1002/tox.22882. Epub 2019 Dec 3.
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HSP 10 is a new autoantigen in both autoimmune pancreatitis and fulminant type 1 diabetes.Biochem Biophys Res Commun. 2009 Aug 14;386(1):192-6. doi: 10.1016/j.bbrc.2009.06.009. Epub 2009 Jun 9.
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Effect of adiponectin level and genetic variation of its receptors on diabetic retinopathy: A case-control study.Medicine (Baltimore). 2019 Mar;98(11):e14878. doi: 10.1097/MD.0000000000014878.
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Correlation between chronic venous ulcer exudate proteins and clinical profile: A cross-sectional study.J Proteomics. 2019 Feb 10;192:280-290. doi: 10.1016/j.jprot.2018.09.009. Epub 2018 Sep 24.
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2-Aminoadipic acid protects against obesity and diabetes.J Endocrinol. 2019 Nov;243(2):111-123. doi: 10.1530/JOE-19-0157.
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Novel protective mechanism of reducing renal cell damage in diabetes: Activation AMPK by AICAR increased NRF2/OGG1 proteins and reduced oxidative DNA damage.Cell Cycle. 2016 Nov 16;15(22):3048-3059. doi: 10.1080/15384101.2016.1231259. Epub 2016 Sep 9.
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Risk factors for Clostridium difficile-associated diarrhea among hospitalized adults with fecal toxigenic C. difficile colonization.J Microbiol Immunol Infect. 2015 Apr;48(2):183-9. doi: 10.1016/j.jmii.2013.08.003. Epub 2013 Sep 21.
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Degenerative aortic valve disease and diabetes: Implications for a link between proteoglycans and diabetic disorders in the aortic valve.Diab Vasc Dis Res. 2019 May;16(3):254-269. doi: 10.1177/1479164118817922. Epub 2018 Dec 19.
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Carbonic anhydrase activation is associated with worsened pathological remodeling in human ischemic diabetic cardiomyopathy.J Am Heart Assoc. 2014 Mar 26;3(2):e000434. doi: 10.1161/JAHA.113.000434.
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Calcium Channel Ca(V)2.3 Subunits Regulate Hepatic Glucose Production by Modulating Leptin-Induced Excitation of Arcuate Pro-opiomelanocortin Neurons.Cell Rep. 2018 Oct 9;25(2):278-287.e4. doi: 10.1016/j.celrep.2018.09.024.
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Update on the pharmacology of calcitonin/CGRP family of peptides: IUPHAR Review 25.Br J Pharmacol. 2018 Jan;175(1):3-17. doi: 10.1111/bph.14075. Epub 2017 Nov 28.
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Calpain Activity in Leukocytes Is Associated with Diabetes Biochemical Markers.Arch Med Res. 2019 Oct;50(7):451-460. doi: 10.1016/j.arcmed.2019.11.009. Epub 2019 Nov 29.
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Selective deletion of endothelial cell calpain in mice reduces diabetic cardiomyopathy by improving angiogenesis.Diabetologia. 2019 May;62(5):860-872. doi: 10.1007/s00125-019-4828-y. Epub 2019 Feb 18.
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NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus.Cells. 2019 Dec 8;8(12):1595. doi: 10.3390/cells8121595.
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Correlation between gene expression of CCK-A receptor and emptying dysfunction of the gallbladder in patients with gallstones and diabetes mellitus.Hepatobiliary Pancreat Dis Int. 2005 May;4(2):295-8.
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CCL21 Expression in -Cells Induces Antigen-Expressing Stromal Cell Networks in the Pancreas and Prevents Autoimmune Diabetes in Mice.Diabetes. 2019 Oct;68(10):1990-2003. doi: 10.2337/db19-0239. Epub 2019 Aug 1.
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Cystatin C and Risk of Diabetes and the Metabolic Syndrome - Biomarker and Genotype Association Analyses.PLoS One. 2016 May 24;11(5):e0155735. doi: 10.1371/journal.pone.0155735. eCollection 2016.
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CD19+IgM+ cells demonstrate enhanced therapeutic efficacy in type 1 diabetes mellitus.JCI Insight. 2018 Dec 6;3(23):e99860. doi: 10.1172/jci.insight.99860.
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High glucose concentrations induce TNF- production through the down-regulation of CD33 in primary human monocytes.BMC Immunol. 2012 Apr 14;13:19. doi: 10.1186/1471-2172-13-19.
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T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10.Nat Immunol. 2013 Jul;14(7):741-8. doi: 10.1038/ni.2610. Epub 2013 May 19.
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Dendritic cell activation is blunted in patients with coronary artery disease and diabetes mellitus.J Diabetes Complications. 2019 Feb;33(2):134-139. doi: 10.1016/j.jdiacomp.2018.11.004. Epub 2018 Nov 23.
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Effects of diabetes and cardiopulmonary bypass on expression of adherens junction proteins in human peripheral tissue.Surgery. 2017 Mar;161(3):823-829. doi: 10.1016/j.surg.2016.08.057. Epub 2016 Nov 9.
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IMAGe and Related Undergrowth Syndromes: The Complex Spectrum of Gain-of-Function CDKN1C Mutations.Pediatr Endocrinol Rev. 2017 Mar;14(3):289-297. doi: 10.17458/per.vol14.2017.SKHD.imageandrelatedundergrowth.
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Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid.Diabetes. 2014 Jan;63(1):259-69. doi: 10.2337/db13-1012. Epub 2013 Sep 23.
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Association of chitotriosidase enzyme activity and genotype with the risk of nephropathy in type 2 diabetes.Clin Biochem. 2016 Apr;49(6):444-448. doi: 10.1016/j.clinbiochem.2015.11.009. Epub 2015 Nov 14.
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APX3330 Promotes Neurorestorative Effects after Stroke in Type One Diabetic Rats.Aging Dis. 2018 Jun 1;9(3):453-466. doi: 10.14336/AD.2017.1130. eCollection 2018 Jun.
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A survey of zeb1, twist and claudin 1 and 4 expression during placental development and disease.APMIS. 2014 Jun;122(6):530-8. doi: 10.1111/apm.12187. Epub 2013 Dec 5.
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Aerobic exercise decreases chemerin/CMKLR1 in the serum and peripheral metabolic organs of obesity and diabetes rats by increasing PPAR.Nutr Metab (Lond). 2019 Mar 5;16:17. doi: 10.1186/s12986-019-0344-9. eCollection 2019.
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The role of CNP-mediated PKG/PKA-PLC pathway in diabetes-induced gastric motility disorder.Peptides. 2018 Dec;110:47-55. doi: 10.1016/j.peptides.2018.10.012. Epub 2018 Nov 1.
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Involvement of ciliary neurotrophic factor in early diabetic retinal neuropathy in streptozotocin-induced diabetic rats.Eye (Lond). 2018 Sep;32(9):1463-1471. doi: 10.1038/s41433-018-0110-7. Epub 2018 May 23.
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Effect of single nucleotide polymorphism in thrombin-activatable fibrinolysis inhibitor on the risk of diabetic macrovascular disease.Blood Coagul Fibrinolysis. 2015 Mar;26(2):185-90. doi: 10.1097/MBC.0000000000000216.
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Dissecting carboxypeptidase E: properties, functions and pathophysiological roles in disease.Endocr Connect. 2017 May;6(4):R18-R38. doi: 10.1530/EC-17-0020. Epub 2017 Mar 27.
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CRY1 circadian gene variant interacts with carbohydrate intake for insulin resistance in two independent populations: Mediterranean and North American.Chronobiol Int. 2014 Jun;31(5):660-7. doi: 10.3109/07420528.2014.886587. Epub 2014 Feb 18.
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c-Src tyrosine kinase mediates high glucose-induced endothelin-1 expression.Int J Biochem Cell Biol. 2016 Jun;75:123-30. doi: 10.1016/j.biocel.2016.04.008. Epub 2016 Apr 19.
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Common genetic variation in the human CTF1 locus, encoding cardiotrophin-1, determines insulin sensitivity.PLoS One. 2014 Jul 15;9(7):e100391. doi: 10.1371/journal.pone.0100391. eCollection 2014.
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Increased levels of the megakaryocyte and platelet expressed cysteine proteases stefin A and cystatin A prevent thrombosis.Sci Rep. 2019 Jul 3;9(1):9631. doi: 10.1038/s41598-019-45805-9.
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Downregulation of cathepsin G reduces the activation of CD4+ T cells in murine autoimmune diabetes.Am J Transl Res. 2017 Nov 15;9(11):5127-5137. eCollection 2017.
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Associations between self-reported diabetes and 78 circulating markers of inflammation, immunity, and metabolism among adults in the United States.PLoS One. 2017 Jul 28;12(7):e0182359. doi: 10.1371/journal.pone.0182359. eCollection 2017.
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Concentration of tacrolimus and major metabolites in kidney transplant recipients as a function of diabetes mellitus and cytochrome P450 3A gene polymorphism.Xenobiotica. 2013 Jul;43(7):641-9. doi: 10.3109/00498254.2012.752118. Epub 2013 Jan 2.
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Association of Cytochrome P450 Genetic Variants with Clopidogrel Resistance and Outcomes in Acute Ischemic Stroke.J Atheroscler Thromb. 2016 Oct 1;23(10):1188-1200. doi: 10.5551/jat.33290. Epub 2016 Mar 8.
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The influence of dopamine-beta-hydroxylase and catechol O-methyltransferase gene polymorphism on the efficacy of insulin detemir therapy in patients with type 2 diabetes mellitus.Diabetol Metab Syndr. 2017 Dec 4;9:97. doi: 10.1186/s13098-017-0295-0. eCollection 2017.
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Overexpression of decorin promoted angiogenesis in diabetic cardiomyopathy via IGF1R-AKT-VEGF signaling.Sci Rep. 2017 Mar 14;7:44473. doi: 10.1038/srep44473.
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Congenital protein losing enteropathy: an inborn error of lipid metabolism due to DGAT1 mutations.Eur J Hum Genet. 2016 Aug;24(9):1268-73. doi: 10.1038/ejhg.2016.5. Epub 2016 Feb 17.
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Increased DNase I activity in diabetes might be associated with injury of pancreas.Mol Cell Biochem. 2014 Aug;393(1-2):23-32. doi: 10.1007/s11010-014-2043-1. Epub 2014 Mar 28.
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Psychometric testing of the Norwegian Diabetes Health Profile (DHP-18) in patients with type 1 diabetes.BMJ Open Diabetes Res Care. 2018 Dec 6;6(1):e000541. doi: 10.1136/bmjdrc-2018-000541. eCollection 2018.
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DYRK1A aggravates cell dysfunction and apoptosis by promoting the phosphorylation and degradation of IRS2.Exp Gerontol. 2019 Oct 1;125:110659. doi: 10.1016/j.exger.2019.110659. Epub 2019 Jul 13.
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Expression profile of endothelin receptors (ETA and ETB) and microRNAs-155 and -199 in the corpus cavernosum of rats submitted to chronic alcoholism and diabetes mellitus.Braz J Med Biol Res. 2018 Mar 1;51(3):e6329. doi: 10.1590/1414-431X20176329.
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Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture.Diabetes. 2010 Sep;59(9):2107-16. doi: 10.2337/db10-0148. Epub 2010 Jun 14.
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Eukaryotic translation initiation factor 5A inhibition alters physiopathology and immune responses in a "humanized" transgenic mouse model of type 1 diabetes.Am J Physiol Endocrinol Metab. 2014 Apr 1;306(7):E791-8. doi: 10.1152/ajpendo.00537.2013. Epub 2014 Feb 4.
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Circulating microRNA-21 is an early predictor of ROS-mediated damage in subjects with high risk of developing diabetes and in drug-nave T2D.Cardiovasc Diabetol. 2019 Feb 25;18(1):18. doi: 10.1186/s12933-019-0824-2.
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GnRH impairs diabetic wound healing through enhanced NETosis.Cell Mol Immunol. 2020 Aug;17(8):856-864. doi: 10.1038/s41423-019-0252-y. Epub 2019 Jun 19.
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PREVALENCE OF DIABETES IN GREATER BEIRUT AREA: WORSENING OVER TIME.Endocr Pract. 2017 Sep;23(9):1091-1100. doi: 10.4158/EP171876.OR. Epub 2017 Jul 6.
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Experimental diabetes impairs maternal reproductive performance in pregnant Wistar rats and their offspring.Syst Biol Reprod Med. 2018 Feb;64(1):60-70. doi: 10.1080/19396368.2017.1395928. Epub 2017 Nov 20.
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The Ala54Thr polymorphism in the fatty acid-binding protein 2 (FABP2) gene is associated with hearing impairment: a preliminary report.Auris Nasus Larynx. 2010 Aug;37(4):496-9. doi: 10.1016/j.anl.2010.01.006. Epub 2010 Mar 3.
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The new bedside ROCky score to predict the complications in patients with intermediate-risk pulmonary embolism.Eur J Intern Med. 2018 Nov;57:58-60. doi: 10.1016/j.ejim.2018.05.036. Epub 2018 Jun 1.
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The type 2 diabetes risk allele of TMEM154-rs6813195 associates with decreased beta cell function in a study of 6,486 Danes.PLoS One. 2015 Mar 23;10(3):e0120890. doi: 10.1371/journal.pone.0120890. eCollection 2015.
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Maternal-Foetal Diabetes Modifies Neonatal Fc Receptor Expression on Human Leucocytes.Scand J Immunol. 2016 Oct;84(4):237-44. doi: 10.1111/sji.12466.
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Fibroblast Growth Factor 1-Transfected Adipose-Derived Mesenchymal Stem Cells Promote Angiogenic Proliferation.DNA Cell Biol. 2017 May;36(5):401-412. doi: 10.1089/dna.2016.3546. Epub 2017 Mar 10.
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Effect and maintenance of the SLIMMER diabetes prevention lifestyle intervention in Dutch primary healthcare: a randomised controlled trial.Nutr Diabetes. 2017 May 8;7(5):e268. doi: 10.1038/nutd.2017.21.
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Circulating Hypoxia Responsive microRNAs (HRMs) and Wound Healing Potentials of Green Tea in Diabetic and Nondiabetic Rat Models.Evid Based Complement Alternat Med. 2019 Jan 1;2019:9019253. doi: 10.1155/2019/9019253. eCollection 2019.
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A Novel Liposome Formulation Carrying Both an Insulin Peptide and a Ligand for Invariant Natural Killer T Cells Induces Accumulation of Regulatory T Cells to Islets in Nonobese Diabetic Mice.J Diabetes Res. 2019 Oct 23;2019:9430473. doi: 10.1155/2019/9430473. eCollection 2019.
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Inactivating hepatic follistatin alleviates hyperglycemia.Nat Med. 2018 Jul;24(7):1058-1069. doi: 10.1038/s41591-018-0048-0. Epub 2018 Jun 4.
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Partial pancreatic transdifferentiation of primary human hepatocytes in the livers of a humanised mouse model.J Gene Med. 2018 May;20(5):e3017. doi: 10.1002/jgm.3017. Epub 2018 Apr 16.
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Mirtazapine may show anti-hyperglycemic effect by decreasing GLUT2 through leptin and galanin expressions in the liver of type 1 diabetic rats.Iran J Basic Med Sci. 2019 Jun;22(6):676-682. doi: 10.22038/ijbms.2019.34529.8190.
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Zinc Oxide Coated Tin Oxide Nanofibers for Improved Selective Acetone Sensing.Nanomaterials (Basel). 2018 Jul 9;8(7):509. doi: 10.3390/nano8070509.
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Ghrelin receptor inverse agonists as a novel therapeutic approach against obesity-related metabolic disease.Diabetes Obes Metab. 2017 Dec;19(12):1740-1750. doi: 10.1111/dom.13020. Epub 2017 Jul 13.
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O-GlcNAcase overexpression reverses coronary endothelial cell dysfunction in type 1 diabetic mice.Am J Physiol Cell Physiol. 2015 Nov 1;309(9):C593-9. doi: 10.1152/ajpcell.00069.2015. Epub 2015 Aug 12.
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High glucose stimulates proliferative capacity of liver cancer cells possibly via O-GlcNAcylation-dependent transcriptional regulation of GJC1.J Cell Physiol. 2018 Jan;234(1):606-618. doi: 10.1002/jcp.26803. Epub 2018 Aug 5.
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Metabolic and gut microbiome changes following GLP-1 or dual GLP-1/GLP-2 receptor agonist treatment in diet-induced obese mice.Sci Rep. 2019 Oct 30;9(1):15582. doi: 10.1038/s41598-019-52103-x.
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HLA DRB1, DQB1 and insulin promoter VNTR polymorphisms: interactions and the association with adult-onset diabetes mellitus in Czech patients.Int J Immunogenet. 2008 Apr;35(2):133-40. doi: 10.1111/j.1744-313X.2008.00749.x. Epub 2008 Feb 11.
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Platelet, monocyte and neutrophil activation and glucose tolerance in South African Mixed Ancestry individuals.Sci Rep. 2017 Jan 16;7:40329. doi: 10.1038/srep40329.
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Effect of tocilizumab, an interleukin-6 inhibitor, on early stage streptozotocin-induced diabetic nephropathy in rats.Naunyn Schmiedebergs Arch Pharmacol. 2019 Aug;392(8):1005-1013. doi: 10.1007/s00210-019-01655-w. Epub 2019 Apr 25.
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Involvement of the metabolic sensor GPR81 in cardiovascular control.JCI Insight. 2017 Oct 5;2(19):e92564. doi: 10.1172/jci.insight.92564.
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Hyperpolarization-activated cyclic nucleotide-gated 2 (HCN2) ion channels drive pain in mouse models of diabetic neuropathy.Sci Transl Med. 2017 Sep 27;9(409):eaam6072. doi: 10.1126/scitranslmed.aam6072.
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Decreased expression of orexin 1 receptor in adult mice testes during alloxan-induced diabetes mellitus perturbs testicular steroidogenesis and glucose homeostasis.Biochem Biophys Res Commun. 2017 Sep 2;490(4):1346-1354. doi: 10.1016/j.bbrc.2017.07.026. Epub 2017 Jul 6.
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HDAC11 deletion reduces fructose-induced cardiac dyslipidemia, apoptosis and inflammation by attenuating oxidative stress injury.Biochem Biophys Res Commun. 2018 Sep 5;503(2):444-451. doi: 10.1016/j.bbrc.2018.04.090. Epub 2018 Jun 29.
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HMGB1 upregulates NF-kB by inhibiting IKB- and associates with diabetic retinopathy.Life Sci. 2020 Jan 15;241:117146. doi: 10.1016/j.lfs.2019.117146. Epub 2019 Dec 7.
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Inactivation of the Ras/MAPK/PPAR signaling axis alleviates diabetic mellitus-induced erectile dysfunction through suppression of corpus cavernosal endothelial cell apoptosis by inhibiting HMGCS2 expression.Endocrine. 2019 Mar;63(3):615-631. doi: 10.1007/s12020-018-1810-2. Epub 2018 Nov 20.
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Effect of garlic on rats with chronic intermittent hypoxia combined with diabetes mellitus.Mol Med Rep. 2018 Apr;17(4):6174-6184. doi: 10.3892/mmr.2018.8568. Epub 2018 Feb 7.
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Mobile phone applications and self-management of diabetes: A systematic review with meta-analysis, meta-regression of 21 randomized trials and GRADE.Diabetes Obes Metab. 2018 Aug;20(8):2009-2013. doi: 10.1111/dom.13307. Epub 2018 May 3.
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Association of genetic variants of the histamine H1 and muscarinic M3 receptors with BMI and HbA1c values in patients on antipsychotic medication.Psychopharmacology (Berl). 2011 Jul;216(2):257-65. doi: 10.1007/s00213-011-2211-x. Epub 2011 Feb 19.
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Optimization of cyclic sulfamide derivatives as 11-hydroxysteroid dehydrogenase 1 inhibitors for the potential treatment of ischemic brain injury.Bioorg Med Chem Lett. 2020 Jan 15;30(2):126787. doi: 10.1016/j.bmcl.2019.126787. Epub 2019 Nov 9.
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Copeptin and insulin resistance: effect modification by age and 11 -HSD2 activity in a population-based study.J Endocrinol Invest. 2018 Jul;41(7):799-808. doi: 10.1007/s40618-017-0807-7. Epub 2017 Dec 12.
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IL-21 regulates SOCS1 expression in autoreactive CD8(+) T cells but is not required for acquisition of CTL activity in the islets of non-obese diabetic mice.Sci Rep. 2019 Oct 25;9(1):15302. doi: 10.1038/s41598-019-51636-5.
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Type I and II Interferon Receptors Differentially Regulate Type 1 Diabetes Susceptibility in Male Versus Female NOD Mice.Diabetes. 2018 Sep;67(9):1830-1835. doi: 10.2337/db18-0331. Epub 2018 Jul 3.
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Interleukin-17 gene polymorphisms in patients with post-transplant diabetes mellitus.Eur Rev Med Pharmacol Sci. 2015 Sep;19(17):3152-6.
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Adenoviral gene transfer of a single-chain IL-23 induces psoriatic arthritis-like symptoms in NOD mice.FASEB J. 2019 Aug;33(8):9505-9515. doi: 10.1096/fj.201900420R. Epub 2019 Jun 6.
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Broad induction of immunoregulatory mechanisms after a short course of anti-IL-7R antibodies in NOD mice.BMC Immunol. 2017 Mar 29;18(1):18. doi: 10.1186/s12865-017-0201-4.
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Downregulated NLRP3 and NLRP1 inflammasomes signaling pathways in the development and progression of type 1 diabetes mellitus.Biomed Pharmacother. 2017 Oct;94:619-626. doi: 10.1016/j.biopha.2017.07.102. Epub 2017 Aug 4.
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Unravelling novel congeners from acetyllysine mimicking ligand targeting a lysine acetyltransferase PCAF bromodomain.J Biomol Struct Dyn. 2018 Dec;36(16):4303-4319. doi: 10.1080/07391102.2017.1415820. Epub 2018 Jan 4.
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An integrative study identifies KCNC2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the Korean population.Sci Rep. 2016 Sep 14;6:33043. doi: 10.1038/srep33043.
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Arrhythmogenic gene remodelling in elderly patients with type 2 diabetes with aortic stenosis and normal left ventricular ejection fraction.Exp Physiol. 2017 Nov 1;102(11):1424-1434. doi: 10.1113/EP086412. Epub 2017 Sep 24.
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Coronary arterial BK channel dysfunction exacerbates ischemia/reperfusion-induced myocardial injury in diabetic mice.Appl Physiol Nutr Metab. 2016 Sep;41(9):992-1001. doi: 10.1139/apnm-2016-0048.
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Shifts in podocyte histone H3K27me3 regulate mouse and human glomerular disease.J Clin Invest. 2018 Jan 2;128(1):483-499. doi: 10.1172/JCI95946. Epub 2017 Dec 11.
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Glucose-Sensitive Myokine/Cardiokine MG53 Regulates Systemic Insulin Response and Metabolic Homeostasis.Circulation. 2019 Feb 12;139(7):901-914. doi: 10.1161/CIRCULATIONAHA.118.037216.
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Pancreatic -cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes.Nucleic Acids Res. 2018 Nov 2;46(19):10302-10318. doi: 10.1093/nar/gky839.
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Gene expression profiling and identification of hub genes in Nellore cattle with different marbling score levels.Genomics. 2020 Jan;112(1):873-879. doi: 10.1016/j.ygeno.2019.06.001. Epub 2019 Jun 3.
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Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1).Diabetes. 2018 Apr;67(4):755-768. doi: 10.2337/db17-0134. Epub 2018 Jan 8.
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Assessment of Serum Concentrations of Adropin, Afamin, and Neudesin in Children with Type 1 Diabetes.Biomed Res Int. 2019 Oct 24;2019:6128410. doi: 10.1155/2019/6128410. eCollection 2019.
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Association between maternal diabetes, being large for gestational age and breast-feeding on being overweight or obese in childhood.Diabetologia. 2019 Feb;62(2):249-258. doi: 10.1007/s00125-018-4758-0. Epub 2018 Nov 13.
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Analysis of circulating lncRNA expression profiles in patients with diabetes mellitus and diabetic nephropathy: Differential expression profile of circulating lncRNA?"Yang Y. Fan Q
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Early growth response protein-1 upregulates long noncoding RNA Arid2-IR to promote extracellular matrix production in diabetic kidney disease.Am J Physiol Cell Physiol. 2019 Mar 1;316(3):C340-C352. doi: 10.1152/ajpcell.00167.2018. Epub 2018 Nov 21.
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Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.JAMA. 2018 Dec 25;320(24):2553-2563. doi: 10.1001/jama.2018.19329.
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MiR-34c Participates in Diabetic Corneal Neuropathy Via Regulation of Autophagy.Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):16-25. doi: 10.1167/iovs.18-24968.
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Hyperglycemia-Induced Oxidative Stress Abrogates Remifentanil Preconditioning-Mediated Cardioprotection in Diabetic Rats by Impairing Caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 Signaling.Oxid Med Cell Longev. 2019 Sep 5;2019:9836302. doi: 10.1155/2019/9836302. eCollection 2019.
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Levels of cytokines and GADA in type I and II diabetic patients.Prim Care Diabetes. 2020 Feb;14(1):61-67. doi: 10.1016/j.pcd.2019.03.008. Epub 2019 Apr 20.
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Patient Reported Outcomes following initiation of Glucagon-like peptide-1 Receptor agonists in patients with type 2 Diabetes in a specialist endocrinology practice of the LMC diabetes registry: The PROGRESS-Diabetes study.Diabetes Res Clin Pract. 2019 Oct;156:107820. doi: 10.1016/j.diabres.2019.107820. Epub 2019 Aug 22.
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Knowledge, attitude and practice among non-ophthalmic health care providers regarding eye management of diabetics in private sector of Riyadh, Saudi Arabia.BMC Health Serv Res. 2019 Jun 13;19(1):375. doi: 10.1186/s12913-019-4216-9.
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Relation of Chronic Total Occlusion to In-Hospital Mortality in the Patients With Sudden Cardiac Arrest Due to Acute Coronary Syndrome.Am J Cardiol. 2019 Jun 15;123(12):1915-1920. doi: 10.1016/j.amjcard.2019.02.059. Epub 2019 Mar 16.
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Cartilage Oligomeric Matrix Protein Levels in Type 2 Diabetes Associated with Primary Knee Osteoarthritis Patients.Genet Test Mol Biomarkers. 2019 Jan;23(1):16-22. doi: 10.1089/gtmb.2018.0184. Epub 2018 Dec 8.
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Coro2b, a podocyte protein downregulated in human diabetic nephropathy, is involved in the development of protamine sulphate-induced foot process effacement.Sci Rep. 2019 Jun 20;9(1):8888. doi: 10.1038/s41598-019-45303-y.
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Changes in tramadol enantioselective pharmacokinetics and metabolism in rats with experimental diabetes treated or not with insulin.Eur J Pharm Sci. 2019 Feb 1;128:97-102. doi: 10.1016/j.ejps.2018.11.032. Epub 2018 Nov 28.
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The effect of diabetes on tooth loss caused by periodontal disease: A nationwide population-based cohort study in South Korea.J Periodontol. 2019 Jun;90(6):576-583. doi: 10.1002/JPER.18-0480. Epub 2019 Mar 12.
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Globally elevating the AGE clearance receptor, OST48, does not protect against the development of diabetic kidney disease, despite improving insulin secretion.Sci Rep. 2019 Sep 20;9(1):13664. doi: 10.1038/s41598-019-50221-0.
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Establishment of a DGK Endogenous Promoter Luciferase Reporter HepG2 Cell Line for Studying the Transcriptional Regulation of DGK Gene.Appl Biochem Biotechnol. 2019 Apr;187(4):1344-1355. doi: 10.1007/s12010-018-2890-4. Epub 2018 Sep 19.
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Diabetes-Induced DUSP4 Reduction Promotes Podocyte Dysfunction and Progression of Diabetic Nephropathy.Diabetes. 2019 May;68(5):1026-1039. doi: 10.2337/db18-0837. Epub 2019 Mar 12.
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Association between area-level socioeconomic status, accessibility and diabetes-related hospitalisations: a cross-sectional analysis of data from Western Victoria, Australia.BMJ Open. 2019 May 22;9(5):e026880. doi: 10.1136/bmjopen-2018-026880.
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Inhibition of Ephrin-B2 in brain pericytes decreases cerebral pathological neovascularization in diabetic rats.PLoS One. 2019 Jan 8;14(1):e0210523. doi: 10.1371/journal.pone.0210523. eCollection 2019.
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Intrauterine exposure to hyperglycemia retards the development of brown adipose tissue.FASEB J. 2019 Apr;33(4):5425-5439. doi: 10.1096/fj.201801818R. Epub 2019 Feb 13.
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Diabetic bone lesions: a study on 38 known modern skeletons and the implications for forensic scenarios.Int J Legal Med. 2019 Jul;133(4):1225-1239. doi: 10.1007/s00414-018-1870-0. Epub 2018 Jun 2.
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Risk factors for postoperative stroke in adults patients with moyamoya disease: a systematic review with meta-analysis.BMC Neurol. 2019 May 15;19(1):98. doi: 10.1186/s12883-019-1327-1.
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Hyperglycemia-Driven Inhibition of AMP-Activated Protein Kinase 2 Induces Diabetic Cardiomyopathy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes In Vivo.Circulation. 2019 Apr 16;139(16):1913-1936. doi: 10.1161/CIRCULATIONAHA.118.033552.
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New Insight into the Mechanisms of Ginkgo Biloba Extract in Vascular Aging Prevention.Curr Vasc Pharmacol. 2020;18(4):334-345. doi: 10.2174/1570161117666190621150725.
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Transgenic expression of the positive selected human GLUD2 gene improves in vivo glucose homeostasis by regulating basic insulin secretion.Metabolism. 2019 Nov;100:153958. doi: 10.1016/j.metabol.2019.153958. Epub 2019 Aug 7.
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Association between incidence of fatal intracerebral hemorrhagic stroke and fine particulate air pollution.Environ Health Prev Med. 2019 Jun 1;24(1):38. doi: 10.1186/s12199-019-0793-9.
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Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis.Diabetes Care. 2019 Feb;42(2):200-207. doi: 10.2337/dc18-1785.
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Diabetes-associated angiotensin activation enhances liver metastasis of colon cancer.Clin Exp Metastasis. 2012 Dec;29(8):915-25. doi: 10.1007/s10585-012-9480-6. Epub 2012 May 3.
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Glutathione peroxidase 4 functional variant rs713041 modulates the risk for cardiovascular autonomic neuropathy in individuals with type 1 diabetes.Diab Vasc Dis Res. 2019 May;16(3):297-299. doi: 10.1177/1479164118820641. Epub 2019 Jan 1.
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Histone HIST1H1C/H1.2 regulates autophagy in the development of diabetic retinopathy.Autophagy. 2017 May 4;13(5):941-954. doi: 10.1080/15548627.2017.1293768. Epub 2017 Mar 2.
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Dysregulation of macrophage development and phenotype in diabetic human macrophages can be rescued by Hoxa3 protein transduction.PLoS One. 2019 Oct 18;14(10):e0223980. doi: 10.1371/journal.pone.0223980. eCollection 2019.
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Heat-Shock Protein 70-Mediated Heat Preconditioning Attenuates Hepatic Carbohydrate and Oxidative Disturbances in Rats With Type 1 Diabetes.Can J Diabetes. 2019 Jul;43(5):345-353. doi: 10.1016/j.jcjd.2019.01.002. Epub 2019 Jan 11.
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Engineering of chimeric peptides as antagonists for the G protein-coupled receptor, RXFP4.Sci Rep. 2019 Nov 28;9(1):17828. doi: 10.1038/s41598-019-53707-z.
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Overproduction of inter--trypsin inhibitor heavy chain 1 after loss of G(13) in liver exacerbates systemic insulin resistance in mice.Sci Transl Med. 2019 Oct 9;11(513):eaan4735. doi: 10.1126/scitranslmed.aan4735.
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From Hyper- to Hypoinsulinemia and Diabetes: Effect of KCNH6 on Insulin Secretion.Cell Rep. 2018 Dec 26;25(13):3800-3810.e6. doi: 10.1016/j.celrep.2018.12.005.
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Impact of diabetes mellitus on functional exercise capacity and pulmonary functions in patients with diabetes and healthy persons.BMC Endocr Disord. 2019 Jan 3;19(1):2. doi: 10.1186/s12902-018-0328-1.
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A novel Ku70 function in colorectal homeostasis separate from nonhomologous end joining.Oncogene. 2014 May 22;33(21):2748-57. doi: 10.1038/onc.2013.234. Epub 2013 Jun 10.
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LRG1 Promotes Diabetic Kidney Disease Progression by Enhancing TGF--Induced Angiogenesis.J Am Soc Nephrol. 2019 Apr;30(4):546-562. doi: 10.1681/ASN.2018060599. Epub 2019 Mar 11.
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Lrrc55 is a novel prosurvival factor in pancreatic islets.Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E794-E804. doi: 10.1152/ajpendo.00028.2019. Epub 2019 Sep 17.
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Lipoprotein lipase deficiency and CETP in streptozotocin-treated apoB-expressing mice.J Lipid Res. 2002 Jun;43(6):872-7.
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Dexmedetomidine restores autophagy and cardiac dysfunction in rats with streptozotocin-induced diabetes mellitus.Acta Diabetol. 2019 Jan;56(1):105-114. doi: 10.1007/s00592-018-1225-9. Epub 2018 Sep 11.
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Effect of Home Enteral Nutrition on Diabetes and Its Management.Nutr Clin Pract. 2019 Apr;34(2):250-256. doi: 10.1002/ncp.10104. Epub 2018 Jul 13.
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Body surface area and glucose tolerance - The smaller the person, the greater the 2-hour plasma glucose.Diabetes Res Clin Pract. 2019 Nov;157:107877. doi: 10.1016/j.diabres.2019.107877. Epub 2019 Oct 14.
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As Time Goes by: Anxiety Negatively Affects the Perceived Quality of Life in Patients With Type 2 Diabetes of Long Duration.Front Psychol. 2019 Jul 31;10:1779. doi: 10.3389/fpsyg.2019.01779. eCollection 2019.
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Roux-en-Y gastric bypass enhances insulin secretion in type 2 diabetes via FXR-mediated TRPA1 expression.Mol Metab. 2019 Nov;29:1-11. doi: 10.1016/j.molmet.2019.08.009. Epub 2019 Aug 15.
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Periodontal status and self-reported systemic health of periodontal patients regularly visiting dental clinics in the 8020 Promotion Foundation Study of Japanese Dental Patients.J Oral Sci. 2019;61(2):238-245. doi: 10.2334/josnusd.18-0128.
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Identification of 22 novel loci associated withurinary biomarkers of albumin, sodium, andpotassium excretion.Kidney Int. 2019 May;95(5):1197-1208. doi: 10.1016/j.kint.2018.12.017. Epub 2019 Mar 12.
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Overexpression of nuclear transport factor 2 may protect against diabetic retinopathy.Mol Vis. 2009;15:861-9. Epub 2009 Apr 27.
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Therapeutic administration of Tregitope-Human Albumin Fusion with Insulin Peptides to promote Antigen-Specific Adaptive Tolerance Induction.Sci Rep. 2019 Nov 6;9(1):16103. doi: 10.1038/s41598-019-52331-1.
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A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.Diabetes. 2018 Jul;67(7):1414-1427. doi: 10.2337/db17-0914. Epub 2018 Apr 27.
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CXCL4L1 Promoter Polymorphisms Are Associated with Improved Renal Function in Type 1 Diabetes.J Immunol. 2019 Feb 1;202(3):912-919. doi: 10.4049/jimmunol.1801086. Epub 2018 Dec 28.
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Peroxiredoxin6, a Multitask Antioxidant Enzyme Involved in the Pathophysiology of Chronic Noncommunicable Diseases.Antioxid Redox Signal. 2019 Jan 20;30(3):399-414. doi: 10.1089/ars.2017.7427. Epub 2018 Jan 2.
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Identification of potential leukocyte antigen-related protein (PTP-LAR) inhibitors through 3D QSAR pharmacophore-based virtual screening and molecular dynamics simulation.J Biomol Struct Dyn. 2020 Sep;38(14):4232-4245. doi: 10.1080/07391102.2019.1676825. Epub 2019 Oct 17.
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Retinol binding protein 3 is increased in the retina of patients with diabetes resistant to diabetic retinopathy.Sci Transl Med. 2019 Jul 3;11(499):eaau6627. doi: 10.1126/scitranslmed.aau6627.
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Reticulocalbin 2 enhances osteogenic differentiation of human vascular smooth muscle cells in diabetic conditions.Life Sci. 2019 Sep 15;233:116746. doi: 10.1016/j.lfs.2019.116746. Epub 2019 Aug 9.
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A point mutation in Sec61alpha1 leads to diabetes and hepatosteatosis in mice. Diabetes. 2010 Feb;59(2):460-70. doi: 10.2337/db08-1362. Epub 2009 Nov 23.
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Differential proteome analysis of serum proteins associated with the development of type 2 diabetes mellitus in the KK-A(y) mouse model using the iTRAQ technique.J Proteomics. 2013 Jun 12;84:40-51. doi: 10.1016/j.jprot.2013.03.014. Epub 2013 Mar 29.
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Role of SLMAP genetic variants in susceptibility of diabetes and diabetic retinopathy in Qatari population.J Transl Med. 2015 Feb 15;13:61. doi: 10.1186/s12967-015-0411-6.
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Serum and urinary SOD3 in patients with type 2 diabetes: comparison with early chronic kidney disease patients and association with development of diabetic nephropathy.Am J Physiol Renal Physiol. 2019 Jan 1;316(1):F32-F41. doi: 10.1152/ajprenal.00401.2017. Epub 2018 Oct 10.
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RAGE and AGEs in Mild Cognitive Impairment of Diabetic Patients: A Cross-Sectional Study.PLoS One. 2016 Jan 8;11(1):e0145521. doi: 10.1371/journal.pone.0145521. eCollection 2016.
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