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Atorvastatin FDA Label
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Fenofibrate FDA Label
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ACR Appropriateness Criteria() Chronic Chest Pain-Noncardiac Etiology Unlikely-Low to Intermediate Probability of Coronary Artery Disease.J Am Coll Radiol. 2018 Nov;15(11S):S283-S290. doi: 10.1016/j.jacr.2018.09.021.
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ADAM33 expression in atherosclerotic lesions and relationship of ADAM33 gene variation with atherosclerosis.Atherosclerosis. 2010 Jul;211(1):224-30. doi: 10.1016/j.atherosclerosis.2010.02.023. Epub 2010 Feb 24.
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Association between ADAMTS1 matrix metalloproteinase gene variation, coronary heart disease, and benefit of statin therapy.Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):562-7. doi: 10.1161/ATVBAHA.107.156653. Epub 2008 Jan 3.
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A novel association between TGFb1 and ADAMTS4 in coronary artery disease: A new potential mechanism in the progression of atherosclerosis and diabetes.Anatol J Cardiol. 2015 Oct;15(10):823-9. doi: 10.5152/akd.2014.5762. Epub 2014 Oct 31.
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The transcriptome of human epicardial, mediastinal and subcutaneous adipose tissues in men with coronary artery disease.PLoS One. 2011;6(5):e19908. doi: 10.1371/journal.pone.0019908. Epub 2011 May 16.
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A nonsynonymous variant I248L of the adenosine A3 receptor is associated with coronary heart disease in a Latvian population.DNA Cell Biol. 2011 Nov;30(11):907-11. doi: 10.1089/dna.2011.1230. Epub 2011 Jun 15.
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2A-Adrenergic receptor polymorphism potentiates platelet reactivity in patients with stable coronary artery disease carrying the cytochrome P450 2C19*2 genetic variant.Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1314-9. doi: 10.1161/ATVBAHA.114.303275. Epub 2014 Apr 10.
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Association of Improvement in Fractional Flow Reserve With Outcomes, Including Symptomatic Relief, After Percutaneous Coronary Intervention.JAMA Cardiol. 2019 Apr 1;4(4):370-374. doi: 10.1001/jamacardio.2019.0175.
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Significant role of ADRB3 rs4994 towards the development of coronary artery disease.Coron Artery Dis. 2014 Jan;25(1):29-34. doi: 10.1097/MCA.0000000000000056.
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Association of ALOX5AP haplotypes with susceptibility to coronary artery disease in a Chinese Han population.Eur J Intern Med. 2012 Jul;23(5):e119-23. doi: 10.1016/j.ejim.2012.02.010. Epub 2012 Mar 14.
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Metabolomic Signature of Angiopoietin-Like Protein 3 Deficiency in Fasting and Postprandial State.Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):665-674. doi: 10.1161/ATVBAHA.118.312021.
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HDL subpopulations containing apoA-I without apoA-II (LpA-I) in patients with angiographically proven coronary artery disease.J Cardiol. 2017 Mar;69(3):523-528. doi: 10.1016/j.jjcc.2016.04.007. Epub 2016 May 8.
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Association Between a CCL17 Genetic Variant and Risk of Coronary Artery Disease in a Chinese Han Population.Circ J. 2017 Dec 25;82(1):224-231. doi: 10.1253/circj.CJ-17-0190. Epub 2017 Aug 8.
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Association of the CCR532 polymorphism and its ligand RANTES-403G/A polymorphism with coronary artery disease: a meta-analysis.Thromb Res. 2013 Mar;131(3):e77-84. doi: 10.1016/j.thromres.2012.07.024. Epub 2013 Jan 9.
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Altered Expression of Complement Regulatory Proteins CD35, CD46, CD55, and CD59 on Leukocyte Subsets in Individuals Suffering From Coronary Artery Disease.Front Immunol. 2019 Aug 29;10:2072. doi: 10.3389/fimmu.2019.02072. eCollection 2019.
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ACAT-1 gene polymorphism is associated with increased susceptibility to coronary artery disease in Chinese Han population: a case-control study.Oncotarget. 2017 Oct 6;8(51):89055-89063. doi: 10.18632/oncotarget.21649. eCollection 2017 Oct 24.
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Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease.Nat Commun. 2016 Jan 29;7:10558. doi: 10.1038/ncomms10558.
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Relationship of Genetic Polymorphisms of Aldosterone Synthase Gene Cytochrome P450 11B2 and Mineralocorticoid Receptors with Coronary Artery Disease in Taiwan.Int J Med Sci. 2016 Feb 1;13(2):117-23. doi: 10.7150/ijms.13862. eCollection 2016.
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Polymorphisms of CYP2C8, CYP2C9 and CYP2C19 and risk of coronary heart disease in Russian population.Gene. 2017 Sep 5;627:451-459. doi: 10.1016/j.gene.2017.07.004. Epub 2017 Jul 4.
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Ophiopogonin D Reduces Myocardial Ischemia-Reperfusion Injury via Upregulating CYP2J3/EETs in Rats.Cell Physiol Biochem. 2018;49(4):1646-1658. doi: 10.1159/000493500. Epub 2018 Sep 18.
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Impact of CYP3A5 polymorphism on platelet reactivity at percutaneous coronary intervention and after 9 months of aspirin and clopidogrel therapy in Japanese patients with coronary artery disease.Eur J Clin Pharmacol. 2014 Jun;70(6):667-73. doi: 10.1007/s00228-014-1672-3. Epub 2014 Apr 26.
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C-338A polymorphism of the endothelin-converting enzyme (ECE-1) gene and the susceptibility to sporadic late-onset Alzheimer's disease and coronary artery disease.Dis Markers. 2008;24(3):175-9. doi: 10.1155/2008/578304.
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ENPP1 K121Q (rs1044498C?A) genetic polymorphism confers a high risk of susceptibility to coronary heart disease: A PRISMA-compliant article.Medicine (Baltimore). 2018 Jul;97(27):e11236. doi: 10.1097/MD.0000000000011236.
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Putting genome analysis to good use: lessons from C-reactive protein and cardiovascular disease.Cleve Clin J Med. 2012 Mar;79(3):182-91. doi: 10.3949/ccjm.79a.09169.
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The tumour necrosis factor superfamily ligand APRIL (TNFSF13) is released upon platelet activation and expressed in atherosclerosis.Thromb Haemost. 2009 Oct;102(4):704-10. doi: 10.1160/TH08-10-0665.
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C-reactive protein-derived peptide 201-206 inhibits neutrophil adhesion to endothelial cells and platelets through CD32.J Leukoc Biol. 2011 Dec;90(6):1167-75. doi: 10.1189/jlb.0111032. Epub 2011 Sep 20.
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Fibroblast growth factor 21 in cardio-metabolic disorders: a systematic review and meta-analysis.Metabolism. 2018 Jun;83:11-17. doi: 10.1016/j.metabol.2018.01.017. Epub 2018 Feb 2.
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Fibroblast growth factor receptor 4 polymorphisms and susceptibility to coronary artery disease.DNA Cell Biol. 2012 Jun;31(6):1064-9. doi: 10.1089/dna.2011.1552. Epub 2012 Feb 7.
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Correlations of degree of coronary artery stenosis with blood lipid, CRP, Hcy, GGT, SCD36 and fibrinogen levels in elderly patients with coronary heart disease.Eur Rev Med Pharmacol Sci. 2019 Nov;23(21):9582-9589. doi: 10.26355/eurrev_201911_19453.
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Human Epicardial Fat Expresses Glucagon-Like Peptide 1 and 2 Receptors Genes.Horm Metab Res. 2017 Aug;49(8):625-630. doi: 10.1055/s-0043-109563. Epub 2017 May 17.
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Decreased levels of platelet-derived soluble glycoprotein VI detected prior to the first diagnosis of coronary artery disease in HIV-positive individuals.Platelets. 2017 May;28(3):301-304. doi: 10.1080/09537104.2016.1237627. Epub 2016 Nov 16.
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Detecting local haplotype sharing and haplotype association.Genetics. 2014 Jul;197(3):823-38. doi: 10.1534/genetics.114.164814. Epub 2014 May 8.
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Degradation of GRK2 and AKT is an early and detrimental event in myocardial ischemia/reperfusion.EBioMedicine. 2019 Oct;48:605-618. doi: 10.1016/j.ebiom.2019.09.019. Epub 2019 Oct 5.
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The Atherosclerosis Risk Variant rs2107595 Mediates Allele-Specific Transcriptional Regulation of HDAC9 via E2F3 and Rb1.Stroke. 2019 Oct;50(10):2651-2660. doi: 10.1161/STROKEAHA.119.026112. Epub 2019 Sep 10.
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Upregulation of microRNA-218 reduces cardiac microvascular endothelial cells injury induced by coronary artery disease through the inhibition of HMGB1.J Cell Physiol. 2020 Mar;235(3):3079-3095. doi: 10.1002/jcp.29214. Epub 2019 Sep 30.
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Association of the HNF1A polymorphisms and serum lipid traits, the risk of coronary artery disease and ischemic stroke.J Gene Med. 2017 Jan;19(1-2):e2941. doi: 10.1002/jgm.2941.
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Serum Heparanase Level Is Decreased in Stable Coronary Artery Disease.Med Princ Pract. 2019;28(6):573-580. doi: 10.1159/000503085. Epub 2019 Sep 4.
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Genetic variations in HSPA8 gene associated with coronary heart disease risk in a Chinese population.PLoS One. 2010 Mar 16;5(3):e9684. doi: 10.1371/journal.pone.0009684.
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T helper cellrelated cytokine gene polymorphisms and vitamin D pathway gene polymorphisms as predictors of survival probability in patients on renal replacement therapy.Pol Arch Med Wewn. 2015;125(7-8):511-20. doi: 10.20452/pamw.2957. Epub 2015 Jun 3.
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Interleukin-15 and soluble interleukin-15 receptor in coronary artery disease patients: association with epicardial fat and indices of adipose tissue distribution.PLoS One. 2014 Mar 6;9(3):e90960. doi: 10.1371/journal.pone.0090960. eCollection 2014.
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The association of interleukin-16 gene polymorphisms with susceptibility of coronary artery disease.Clin Biochem. 2013 Feb;46(3):241-4. doi: 10.1016/j.clinbiochem.2012.11.009. Epub 2012 Nov 27.
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The IL-33-ST2L pathway is associated with coronary artery disease in a Chinese Han population.Am J Hum Genet. 2013 Oct 3;93(4):652-60. doi: 10.1016/j.ajhg.2013.08.009. Epub 2013 Sep 26.
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The association between IL-17A and IL-23R polymorphisms and coronary artery disease risk in a Middle Eastern Chinese population.J Clin Lab Anal. 2019 Jul;33(6):e22893. doi: 10.1002/jcla.22893. Epub 2019 May 10.
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Circulating Levels of LAMP2 in Coronary Artery Disease: Association with Serum Lipid Profile.Horm Metab Res. 2017 Feb;49(2):109-114. doi: 10.1055/s-0042-119649. Epub 2016 Dec 6.
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Is Chronic Low Back Pain Associated with the Prevalence of Coronary Heart Disease when Genetic Susceptibility Is Considered? A Co-Twin Control Study of Spanish Twins.PLoS One. 2016 May 12;11(5):e0155194. doi: 10.1371/journal.pone.0155194. eCollection 2016.
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Lysosomal Acid Lipase in Lipid Metabolism and Beyond.Arterioscler Thromb Vasc Biol. 2019 May;39(5):850-856. doi: 10.1161/ATVBAHA.119.312136.
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Association of 584C/T polymorphism in endothelial lipase gene with risk of coronary artery disease.J Cell Biochem. 2019 Sep;120(9):14414-14420. doi: 10.1002/jcb.28697. Epub 2019 Apr 24.
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TCF7L2 (Transcription Factor 7-Like 2) Regulation of GATA6 (GATA-Binding Protein 6)-Dependent and -Independent Vascular Smooth Muscle Cell Plasticity and Intimal Hyperplasia.Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):250-262. doi: 10.1161/ATVBAHA.118.311830.
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Extended evidence for association between the melanoma inhibitory activity 3 gene and myocardial infarction.Thromb Haemost. 2011 Apr;105(4):670-5. doi: 10.1160/TH10-10-0641. Epub 2011 Jan 25.
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The effect of MVK-MMAB variants, their haplotypes and GE interactions on serum lipid levels and the risk of coronary heart disease and ischemic stroke.Oncotarget. 2017 Aug 18;8(42):72801-72817. doi: 10.18632/oncotarget.20349. eCollection 2017 Sep 22.
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Association of 25 bp deletion in MYBPC3 gene with left ventricle dysfunction in coronary artery disease patients.PLoS One. 2011;6(9):e24123. doi: 10.1371/journal.pone.0024123. Epub 2011 Sep 7.
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Mutant DD genotype of NFKB1 gene is associated with the susceptibility and severity of coronary artery disease.J Mol Cell Cardiol. 2017 Feb;103:56-64. doi: 10.1016/j.yjmcc.2017.01.005. Epub 2017 Jan 12.
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Genetics of adipose tissue biology.Prog Mol Biol Transl Sci. 2010;94:39-74. doi: 10.1016/B978-0-12-375003-7.00003-0.
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High doses of ANP and BNP exacerbate lipolysis in humans and the lipolytic effect of BNP is associated with cardiac triglyceride content in pigs.Peptides. 2019 Feb;112:43-47. doi: 10.1016/j.peptides.2018.11.003. Epub 2018 Nov 30.
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Medications that reduce emergency hospital admissions: an overview of systematic reviews and prioritisation of treatments.BMC Med. 2018 Jul 26;16(1):115. doi: 10.1186/s12916-018-1104-9.
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Successful intravenous thrombolysis for ischemic stroke as a complication of coronary intervention in patients with ticagrelor pretreatment.J Clin Neurosci. 2020 Jan;71:283-286. doi: 10.1016/j.jocn.2019.10.007. Epub 2019 Oct 26.
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Genetic variants in PCSK1 gene are associated with the risk of coronary artery disease in type 2 diabetes in a Chinese Han population: a case control study.PLoS One. 2014 Jan 28;9(1):e87168. doi: 10.1371/journal.pone.0087168. eCollection 2014.
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PDE4D gene polymorphisms and coronary heart disease: a case-control study in a north Indian population.J Clin Lab Anal. 2013 Jul;27(4):297-300. doi: 10.1002/jcla.21601.
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Associations between the CDKN2A/B, ADTRP and PDGFD polymorphisms and the development of coronary atherosclerosis in Japanese patients.J Atheroscler Thromb. 2014;21(7):680-90. doi: 10.5551/jat.22640. Epub 2014 Mar 26.
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Decoy receptor-3 regulates inflammation and apoptosis via PI3K/AKT signaling pathway in coronary heart disease.Exp Ther Med. 2019 Apr;17(4):2614-2622. doi: 10.3892/etm.2019.7222. Epub 2019 Jan 30.
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Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease.J Thromb Haemost. 2020 Jan;18(1):234-242. doi: 10.1111/jth.14635. Epub 2019 Oct 20.
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The role of PRKCH gene variants in coronary artery disease in a Chinese population.Mol Biol Rep. 2012 Feb;39(2):1777-82. doi: 10.1007/s11033-011-0918-8. Epub 2011 May 29.
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Serum retinol-binding protein 4 is associated with the presence and severity of coronary artery disease in patients with subclinical hypothyroidism.Aging (Albany NY). 2019 Jul 6;11(13):4510-4520. doi: 10.18632/aging.102065.
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SENP1 protects against myocardial ischaemia/reperfusion injury via a HIF1-dependent pathway.Cardiovasc Res. 2014 Oct 1;104(1):83-92. doi: 10.1093/cvr/cvu177. Epub 2014 Jul 31.
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PHACTR1 and SLC22A3 gene polymorphisms are associated with reduced coronary artery disease risk in the male Chinese Han population.Oncotarget. 2017 Jan 3;8(1):658-663. doi: 10.18632/oncotarget.13506.
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Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk.PLoS Genet. 2018 Oct 11;14(10):e1007681. doi: 10.1371/journal.pgen.1007681. eCollection 2018 Oct.
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Association between a thyroid hormone receptor- gene polymorphism and blood pressure but not with coronary heart disease risk.Am J Hypertens. 2011 Sep;24(9):1027-34. doi: 10.1038/ajh.2011.94. Epub 2011 Jun 9.
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Toll-like receptor 8 polymorphism and coronary artery disease.Mol Biol Rep. 2009 Sep;36(7):1897-901. doi: 10.1007/s11033-008-9396-z. Epub 2008 Nov 5.
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T4 Increases Neovascularization and Cardiac Function in Chronic Myocardial Ischemia of Normo- and Hypercholesterolemic Pigs.Mol Ther. 2018 Jul 5;26(7):1706-1714. doi: 10.1016/j.ymthe.2018.06.004. Epub 2018 Jun 19.
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Predictive Value of Osteoprotegerin for Detecting Coronary Artery Calcification in Type 2 Diabetes Mellitus Patients in Correlation with Extent of Calcification Detected by Multidetector Computed Tomography.Endocr Metab Immune Disord Drug Targets. 2019;19(6):845-851. doi: 10.2174/1871530319666190211122858.
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The role of OX40L and ICAM-1 in the stability of coronary atherosclerotic plaques and their relationship with sudden coronary death.BMC Cardiovasc Disord. 2019 Nov 29;19(1):272. doi: 10.1186/s12872-019-1251-8.
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VKORC1 rs2359612C allele is associated with increased risk of coronary artery disease in the presence of coronary calcification.Hum Genet. 2013 Jan;132(1):29-37. doi: 10.1007/s00439-012-1222-y. Epub 2012 Aug 23.
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Effect of ZNF217 gene polymorphisms on colorectal cancer development in a Mexican population.Genet Mol Res. 2015 Jan 23;14(1):362-7. doi: 10.4238/2015.January.23.9.
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Genomic structural variations for cardiovascular and metabolic comorbidity.Sci Rep. 2017 Jan 25;7:41268. doi: 10.1038/srep41268.
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Epigenetics-by-Sex Interaction for Coronary Artery Disease Risk Conferred by the Cystathionine -Lyase Gene Promoter Methylation.OMICS. 2017 Dec;21(12):741-748. doi: 10.1089/omi.2017.0149. Epub 2017 Nov 27.
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Relation of coagulation factor XI with incident coronary heart disease and stroke: the Cardiovascular Health Study.Blood Coagul Fibrinolysis. 2017 Jul;28(5):389-392. doi: 10.1097/MBC.0000000000000616.
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International trends in clinical characteristics and oral anticoagulation treatment for patients with atrial fibrillation: Results from the GARFIELD-AF, ORBIT-AF I, and ORBIT-AF II registries.Am Heart J. 2017 Dec;194:132-140. doi: 10.1016/j.ahj.2017.08.011. Epub 2017 Aug 24.
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Arginase-2 protects myocardial ischemia-reperfusion injury via NF-B/TNF- pathway.Eur Rev Med Pharmacol Sci. 2018 Oct;22(19):6529-6537. doi: 10.26355/eurrev_201810_16067.
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Comparison of Framingham risk score and chest-CT identified coronary artery calcification in breast cancer patients to predict cardiovascular events.Int J Cardiol. 2019 Aug 15;289:138-143. doi: 10.1016/j.ijcard.2019.01.056. Epub 2019 Jan 23.
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Common and Rare Genetic Variation in CCR2, CCR5, or CX3CR1 and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic Traits.Circ Cardiovasc Genet. 2016 Jun;9(3):250-8. doi: 10.1161/CIRCGENETICS.115.001374. Epub 2016 Mar 24.
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TXNIP/Redd1 signalling and excessive autophagy: a novel mechanism of myocardial ischaemia/reperfusion injury in mice.Cardiovasc Res. 2020 Mar 1;116(3):645-657. doi: 10.1093/cvr/cvz152.
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Modulation of gene expression by Polyalthia longifolia in postmenopausal women with coronary artery disease: an in vitro study. J Cardiovasc Transl Res. 2010 Oct;3(5):570-9.
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Activation of cardiac AMPK-FGF21 feed-forward loop in acute myocardial infarction: Role of adrenergic overdrive and lipolysis byproducts.Sci Rep. 2019 Aug 14;9(1):11841. doi: 10.1038/s41598-019-48356-1.
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Fucosyltransferase 3 polymorphism and atherothrombotic disease in the Framingham Offspring Study.Am Heart J. 2007 Apr;153(4):636-9. doi: 10.1016/j.ahj.2006.12.015.
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GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function.J Am Coll Cardiol. 2008 Jul 8;52(2):158-65. doi: 10.1016/j.jacc.2007.12.062.
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Modulation of Ion Channels in the Superior Cervical Ganglion Neurons by Myocardial Ischemia and Fluvastatin Treatment.Front Physiol. 2018 Sep 10;9:1157. doi: 10.3389/fphys.2018.01157. eCollection 2018.
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Knockdown the P2X3 receptor in the stellate ganglia of rats relieved the diabetic cardiac autonomic neuropathy.Neurochem Int. 2018 Nov;120:206-212. doi: 10.1016/j.neuint.2018.09.002. Epub 2018 Sep 6.
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Targeting PPAR for the Treatment and Understanding of Cardiovascular Diseases.Cell Physiol Biochem. 2018;51(6):2760-2775. doi: 10.1159/000495969. Epub 2018 Dec 12.
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