General Information of Disease (ID: DISK1O5Z)

Disease Name Non-insulin dependent diabetes
Synonyms
hypertension, insulin resistance-related, susceptibility to; type 2 diabetes mellitus, susceptibility to; diabetes mellitus, type 2, protection against; diabetes mellitus, type II, susceptibility to; maturity-onset diabetes; insulin resistance, susceptibility to; diabetes mellitus, type 2, susceptibility to; diabetes mellitus, noninsulin-dependent, susceptibility to; diabetes mellitus, non-insulin-dependent, susceptibility to; diabetes mellitus, noninsulin-dependent, 2; diabetes mellitus, noninsulin-dependent, late onset; insulin resistance, severe, digenic; non-insulin-dependent diabetes mellitus; noninsulin-dependent diabetes mellitus; diabetes mellitis type II; non-insulin dependent diabetes mellitus; non-insulin dependent diabetes; type II diabetes mellitus; adult onset diabetes; diabetes mellitus, type II; type II diabetes; T2DM; adult-onset diabetes; T2DM - type 2 diabetes mellitus; type 2 diabetes; type 2 diabetes mellitus; diabetes mellitus, type 2; type 2 diabetes mellitus non-insulin dependent; diabetes mellitus, noninsulin-dependent; T2D; diabetes mellitus, noninsulin-dependent, association with; noninsulin dependent diabetes; diabetes, type 2; diabetes mellitis type 2; NIDDM
Disease Class 5A11: Type 2 diabetes mellitus
Definition
A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.
Disease Hierarchy
DISIUHAP: Type-1/2 diabetes
DISK1O5Z: Non-insulin dependent diabetes
ICD Code
ICD-11
ICD-11: 5A11
Expand ICD-11
'5A11
Expand ICD-10
'E11; 'E11.0; 'E11.1; 'E11.2; 'E11.3; 'E11.4; 'E11.5; 'E11.6; 'E11.7; 'E11.8; 'E11.9
Disease Identifiers
MONDO ID
MONDO_0005148
MESH ID
D003924
UMLS CUI
C0011860
OMIM ID
125853
MedGen ID
41523
HPO ID
HP:0005978
SNOMED CT ID
44054006

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 18 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Acarbose DMRM3AW Approved Small molecular drug [1]
Atorvastatin DMF28YC Approved Small molecular drug [2]
Canagliflozin DMFRM1I Approved Small molecular drug [3]
Chlorpropamide DMPHZQE Approved Small molecular drug [4]
Dapagliflozin DM28UJG Approved Small molecular drug [5]
Exenatide DMYHBKN Approved Small molecular drug [6]
Glibenclamide DM8JXPZ Approved Small molecular drug [7]
Glisoxepide DMJPR2B Approved Small molecular drug [8]
Insulin-glargine DMR4HIW Approved Small molecular drug [9]
Insulin-lispro DM4O90W Approved Small molecular drug [10]
Linagliptin DMWFJTR Approved Small molecular drug [11]
Liraglutide DM3FXPS Approved Small molecular drug [12]
Metformin DM89QE1 Approved Small molecular drug [13]
Pioglitazone DMKJ485 Approved Small molecular drug [14]
Rifampicin DM5DSFZ Approved NA [15]
Sitagliptin DMGDKXN Approved Small molecular drug [16]
Tolbutamide DM02AWV Approved Small molecular drug [17]
Voglibose DMUBP9O Approved Small molecular drug [18]
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⏷ Show the Full List of 18 Drug(s)
This Disease is Treated as An Indication in 14 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
BVT.2733 DM6RUKX Phase 3 Small molecular drug [19]
CJ-30001 DM3X7PF Phase 3 NA [20]
CJ-30002 DMK6LO6 Phase 3 NA [20]
GSK-523338 DMTNYJF Phase 3 NA [21]
Oral-lyn DMGTMMC Phase 3 NA [22]
SYR-472 DM9L1AC Phase 3 Small molecular drug [23]
Isosteviol DMO65WU Phase 2 Small molecular drug [24]
LGD-6972 DMPL9KG Phase 2 NA [25]
BYK-324677 DMKDVVC Phase 1 NA [26]
LY-2393910 DM5CSPI Phase 1 NA [27]
MK-6349 DMPHRJB Phase 1 NA [28]
PF-05161704 DMMAT8O Phase 1 NA [29]
RO-5095932 DM2QYYW Phase 1 NA [30]
SLV-341 DMRJVE5 Phase 1 NA [31]
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⏷ Show the Full List of 14 Drug(s)
This Disease is Treated as An Indication in 11 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
EML-16257 DMWJVBK Discontinued in Phase 2 NA [32]
ASP-4178 DMN5V6I Discontinued in Phase 1 NA [33]
ASP-5034 DMYQPVP Discontinued in Phase 1 NA [34]
NN-4201 DMODR16 Discontinued in Phase 1 NA [35]
NN-9925 DMJT42B Discontinued in Phase 1 NA [36]
PF-915275 DMB7EIN Discontinued in Phase 1 Small molecular drug [37]
CHF-1522 DMPS4NZ Terminated NA [38]
FM-TP4000 DMB89X7 Terminated NA [39]
R-1458 DM58761 Terminated NA [40]
R-765 DMG84S8 Terminated NA [41]
SDZ-PGU-693 DMBXNBR Terminated NA [42]
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⏷ Show the Full List of 11 Drug(s)
This Disease is Treated as An Indication in 38 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
2-18F-FE-5-Br-glyburide DMXWS9M Investigative NA [43]
AIK11 DMRSEGZ Investigative NA [43]
ALL-4 DMRYJ93 Investigative NA [43]
AR-7947 DM34P90 Investigative NA [44]
AS-1907417 DM0MAIW Investigative Small molecular drug [45]
AS-1949490 DMZ1OO0 Investigative Small molecular drug [43]
ATL-801 DMAZ0EQ Investigative Small molecular drug [46]
BIA DM4RZ9A Investigative Small molecular drug [47]
BL-6010 DMEOOV5 Investigative NA [43]
CAM-2036 DM4FVDS Investigative NA [48]
CAT-1904 DME5VHJ Investigative NA [43]
CNTO-736 DMZ57O1 Investigative NA [48]
CNX-010 DMDK5BL Investigative NA [49]
CNX-011 DM5T401 Investigative NA [50]
DB-160 DMEST0R Investigative NA [23]
DC-9703 DM62IBX Investigative NA [51]
DSR-17759 DM4EKHR Investigative NA [25]
FPT-038 DM0T2LQ Investigative NA [51]
GLP-1 receptor PAM DMU2ARC Investigative NA [43]
Glucagon-like peptide-1 analog DMZLRY2 Investigative NA [48]
GSK-1108167A DMSFHFL Investigative NA [43]
KR-62436 DM7G8KR Investigative Small molecular drug [52]
LC34AD3 DMGWSCI Investigative NA [44]
M-2001 DM8LXGE Investigative Small molecular drug [43]
MBX-3254 DM89WA1 Investigative NA [44]
NPB-1 DMVH3AK Investigative NA [43]
NPT-1162 DMASSWE Investigative NA [43]
PK-44 DM40HWI Investigative NA [23]
Retagliptin DMQFSI5 Investigative NA [23]
RO-5212651 DMP0GA6 Investigative NA [44]
SERX-1 DMLW8KE Investigative NA [43]
SKL-18287 DMXS9V8 Investigative NA [48]
SKL-19014 DM5T4Y1 Investigative NA [53]
SMT-14224 DMD4501 Investigative NA [43]
SX-GLP1 DMT53U6 Investigative NA [48]
TUG-469 DM8YN42 Investigative NA [50]
VVP-100X DMEZAND Investigative NA [51]
XMetS DM6JKL7 Investigative Antibody [51]
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⏷ Show the Full List of 38 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1180 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
WFS1 OTYF2UYI Limited Unknown [54]
ABCC8 OTCWQ54I Limited Autosomal dominant [685]
ACAA1 OTVKRET0 Limited Genetic Variation [753]
ACAD8 OT3JI5GB Limited Genetic Variation [754]
ACD OTC54EPO Limited Biomarker [223]
ACOT7 OT7C68YV Limited Genetic Variation [55]
ACSL1 OTB06ESI Limited Genetic Variation [366]
ACTBL2 OTD6B81U Limited Genetic Variation [55]
ACTG2 OTRDWUO0 Limited Genetic Variation [55]
ADD1 OTTF68DC Limited Biomarker [755]
AKAP13 OTOZAR14 Limited Biomarker [226]
AKNAD1 OTOMYU7T Limited Genetic Variation [756]
AKT2 OTBB632K Limited Autosomal dominant [62]
ALDH6A1 OT8LCZCT Limited Genetic Variation [757]
ALDH7A1 OTV57BZD Limited Biomarker [758]
ALG1 OTVXPA9E Limited Altered Expression [759]
ALMS1 OTW66JKS Limited Biomarker [760]
AMH OT5FH4BD Limited Altered Expression [761]
ANK2 OTWB4R1Y Limited Genetic Variation [762]
ANKK1 OT0OM1O0 Limited Biomarker [763]
AP3S1 OTI5UTF6 Limited Genetic Variation [164]
AP3S2 OTN8P9OE Limited Genetic Variation [113]
APOC4 OTE8ZUXY Limited Altered Expression [764]
APPL1 OT8VR95S Limited Genetic Variation [765]
APPL2 OT9S4C4K Limited Genetic Variation [765]
AQP2 OTQLBKK6 Limited Genetic Variation [766]
ARC OTN2QQPG Limited Biomarker [767]
ARID5B OTUQ4CQY Limited Genetic Variation [768]
ATP5PO OTU3MCTN Limited Genetic Variation [769]
ATP8A1 OT2B7XBT Limited Biomarker [770]
AUTS2 OTAEXHSC Limited Genetic Variation [113]
BCAR1 OTKT2C2N Limited Genetic Variation [771]
BCL2L11 OTNQQWFJ Limited Biomarker [73]
BEAN1 OT0WLH27 Limited Biomarker [772]
BHMT OTYB6PXZ Limited Biomarker [718]
BIN1 OTK8O0X8 Limited Biomarker [773]
BMS1 OTEGQ8ZO Limited Genetic Variation [774]
BNC2 OTU22H9Z Limited Genetic Variation [775]
BRAP OTB7BAFQ Limited Biomarker [776]
BRINP1 OTEUVSCP Limited Altered Expression [777]
BSCL2 OT73V6Y4 Limited Genetic Variation [778]
BTN2A1 OTUYPMZJ Limited Biomarker [779]
C1QTNF5 OTLKU5I2 Limited Altered Expression [780]
C1QTNF9 OTLI3VA3 Limited Altered Expression [781]
C4A OTXMOYXU Limited Biomarker [782]
CACNB3 OTP30DIU Limited Biomarker [783]
CAMK1D OTU24HAU Limited Genetic Variation [113]
CAPN5 OTQ8QM7K Limited Genetic Variation [784]
CAPN9 OTE4IU5U Limited Biomarker [785]
CARD8 OTXXZYWU Limited Genetic Variation [786]
CASQ1 OTAY8WOO Limited Genetic Variation [787]
CASZ1 OTWJ2OR8 Limited Altered Expression [690]
CAV2 OT1FGRQX Limited Genetic Variation [788]
CCAR2 OTLUDG5T Limited Altered Expression [777]
CCDC92 OT1YHLOR Limited Genetic Variation [73]
CCL7 OTDIS99H Limited Biomarker [84]
CCL8 OTCTWYN8 Limited Biomarker [84]
CD226 OT4UG0KB Limited Altered Expression [789]
CD247 OT45FGUX Limited Altered Expression [790]
CD2AP OTC76KQM Limited Biomarker [791]
CD300LG OT0O80C9 Limited Genetic Variation [792]
CD48 OT83ZNPP Limited Biomarker [793]
CD68 OTOYEY3J Limited Biomarker [515]
CDK11A OTN5TSGQ Limited Genetic Variation [794]
CDKN3 OTBE3H07 Limited Biomarker [795]
CDO1 OTLG1P77 Limited Biomarker [718]
CEACAM7 OTKFDTZY Limited Altered Expression [88]
CELF4 OT4FS4F5 Limited Genetic Variation [155]
CENPA OT0NEJ4X Limited Altered Expression [796]
CIDEA OTDUTSOV Limited Altered Expression [797]
CILP2 OTAFSWG1 Limited Altered Expression [798]
CISD2 OTVS7S2H Limited Biomarker [799]
CISH OT8T5NYL Limited Posttranslational Modification [800]
CLCN5 OT9YXZSO Limited Biomarker [801]
CLDN19 OTVD6IBL Limited Genetic Variation [693]
CLPS OTGY6QZ0 Limited Genetic Variation [802]
CMIP OTZN8Z4A Limited Genetic Variation [803]
CNKSR2 OTAGERJ2 Limited Genetic Variation [113]
CNNM1 OTHRSSGH Limited Genetic Variation [693]
COBL OTTB4VFQ Limited Biomarker [804]
COBLL1 OTQFN1TC Limited Genetic Variation [113]
COL8A1 OTWBTED2 Limited Genetic Variation [805]
CORT OTX3GUHB Limited Altered Expression [690]
COX10 OTCYIS0L Limited Genetic Variation [806]
COX5B OTDP94F3 Limited Genetic Variation [806]
COX7A1 OTHV25GG Limited Genetic Variation [807]
CREBRF OT2GK1HI Limited Genetic Variation [808]
CREM OTJIJ5AL Limited Altered Expression [809]
CSHL1 OTQKU2F5 Limited Genetic Variation [810]
CTRL OTB6NA5O Limited Biomarker [811]
DACT1 OT19Z704 Limited Altered Expression [812]
DBI OT884QY9 Limited Genetic Variation [813]
DCD OTV5PBGJ Limited Genetic Variation [157]
DEFA1 OT5N1B9B Limited Genetic Variation [814]
DEFA3 OTO3N8E1 Limited Genetic Variation [814]
DEFB103B OT8RWY64 Limited Biomarker [104]
DGKB OTTT9SZJ Limited Genetic Variation [113]
DISC1 OT43AW4H Limited Biomarker [815]
DKK4 OTWCCVF6 Limited Biomarker [816]
DMAP1 OT1ZMQTU Limited Posttranslational Modification [817]
DMBT1 OTVNU9D9 Limited Biomarker [558]
DNAJC3 OT7ROIJF Limited Autosomal dominant [727]
DNTT OTFSEF12 Limited Genetic Variation [818]
DOC2B OTRUMZ8C Limited Biomarker [819]
DPT OTINRFC7 Limited Biomarker [228]
DQX1 OTE7BT00 Limited Biomarker [820]
DUSP6 OT4H6RKW Limited Altered Expression [821]
EFNB2 OT0DCUOM Limited Genetic Variation [822]
EHD1 OTDMEKLV Limited Genetic Variation [823]
EIF4A2 OT08H03R Limited Biomarker [824]
ELMO1 OTY2ORXK Limited Altered Expression [825]
ENO1 OTB1KWJS Limited Biomarker [826]
ENOX1 OT4WOLA8 Limited Altered Expression [827]
EPC2 OTTG0W9R Limited Genetic Variation [113]
ERO1A OTVKOQWM Limited Altered Expression [828]
EXOC4 OT5EWXAN Limited Genetic Variation [829]
EXOG OTZAI8L7 Limited Biomarker [830]
FADS3 OT9RVXGE Limited Genetic Variation [831]
FAM234A OT11NKWC Limited Genetic Variation [366]
FAM78B OTIY35CP Limited Altered Expression [832]
FBN1 OTYCJT63 Limited Biomarker [833]
FBXO28 OTKTMVC4 Limited Altered Expression [834]
FHL5 OT6C00Z1 Limited Genetic Variation [55]
FLII OT7G9JG6 Limited Biomarker [835]
FLVCR1 OT9XCFOC Limited Genetic Variation [836]
FOXA2 OTJOCVOY Limited Altered Expression [837]
FOXA3 OTRGT2OT Limited Biomarker [838]
FUT6 OTBZUQ7F Limited Genetic Variation [839]
G0S2 OT8FL49L Limited Biomarker [840]
GAL3ST1 OTSFFZRD Limited Altered Expression [690]
GALNT2 OTZZ5386 Limited Altered Expression [841]
GDF3 OTD3KGJK Limited Altered Expression [842]
GH2 OT32TR4C Limited Genetic Variation [843]
GK OTK2YRA0 Limited Biomarker [844]
GP2 OTB6TMGY Limited Biomarker [113]
GPM6A OT8G13EG Limited Genetic Variation [845]
GPR21 OTVP8PD1 Limited Biomarker [846]
GPR61 OTK8XH8M Limited Genetic Variation [847]
GPX3 OT6PK94R Limited Biomarker [848]
GRAMD2B OTGT3E98 Limited Genetic Variation [849]
GRB14 OTFET2YM Limited Genetic Variation [113]
GSC OT4DH7PR Limited Genetic Variation [775]
GYG1 OT9PU6I2 Limited Biomarker [850]
HADH OTJDOL20 Limited Genetic Variation [717]
HAS3 OTPM8IL8 Limited Genetic Variation [851]
HIPK3 OT4WYQM2 Limited Genetic Variation [852]
HLA-DMB OT17HGXJ Limited Biomarker [853]
HLA-DQB1 OTVVI3UI Limited Genetic Variation [366]
HLA-DRB5 OTUX5TWM Limited Genetic Variation [73]
HMG20A OTASVPIF Limited Altered Expression [854]
HMGA1 OTQUSHPX Limited Autosomal dominant [141]
HOMER1 OTWFD3SI Limited Altered Expression [855]
HPX OT14T7Q1 Limited Biomarker [856]
HS6ST3 OTTW9PDL Limited Biomarker [857]
HSPA14 OTZCA5LK Limited Genetic Variation [858]
IGF2BP1 OT9G360P Limited Genetic Variation [859]
IGF2BP3 OTB97VIK Limited Genetic Variation [859]
IGFALS OTTWCZYM Limited Biomarker [860]
IK OTWSSXX0 Limited Biomarker [106]
IMMP2L OT9WGAFD Limited Biomarker [776]
IMPA1 OTBUVW1Z Limited Biomarker [776]
IMPACT OTQ923OB Limited Biomarker [861]
INS-IGF2 OTZR74BO Limited Genetic Variation [332]
IP6K1 OTKS4P2T Limited Genetic Variation [862]
IRX3 OTLJ48FG Limited Biomarker [863]
JADE2 OTVG2MYF Limited Genetic Variation [73]
JPH3 OTHTJO2I Limited Genetic Variation [864]
KALRN OT8WRCBH Limited Genetic Variation [865]
KCNK16 OT3GFTFZ Limited Genetic Variation [803]
KCTD15 OTM6L4A0 Limited Biomarker [866]
KEL OT47DJW0 Limited Genetic Variation [867]
KIDINS220 OTLBH2MA Limited Genetic Variation [868]
KIR3DL1 OTPOSXFX Limited Biomarker [123]
KRT31 OTB6RCAH Limited Genetic Variation [869]
LAMA1 OTQZMP86 Limited Genetic Variation [366]
LARS1 OT4557NF Limited Genetic Variation [870]
LIAS OTOSW67J Limited Altered Expression [871]
LIN7C OTB3015O Limited Biomarker [866]
LPIN2 OTRRTMXX Limited Genetic Variation [872]
LPP OT6TU8SE Limited Genetic Variation [873]
LRGUK OTWO612W Limited Genetic Variation [829]
MAFB OTH2N3T8 Limited Biomarker [874]
MAFK OTZJUE4P Limited Biomarker [875]
MAN1A1 OT6LIGJP Limited Biomarker [876]
MARCHF1 OTI2EYO6 Limited Biomarker [877]
MARCHF8 OTH7PNN2 Limited Biomarker [878]
MAX OTKZ0YKM Limited Biomarker [226]
MCAT OTH07FIW Limited Biomarker [879]
MCTS1 OT7SAOJP Limited Biomarker [879]
MEF2C OTZGF1Y5 Limited Genetic Variation [880]
METRN OTI2645G Limited Genetic Variation [881]
MFSD9 OT1XOM6Z Limited Genetic Variation [69]
MGAT4A OT0ZW5FM Limited Altered Expression [882]
MGAT4C OTQ2R629 Limited Genetic Variation [849]
MGP OTZWU3FU Limited Biomarker [883]
MGST3 OTYK80JA Limited Genetic Variation [884]
MIER1 OTT0UJAS Limited Genetic Variation [885]
MLKL OTDSLC81 Limited Biomarker [886]
MLXIP OT30UNI7 Limited Biomarker [878]
MMP26 OT9O89KU Limited Genetic Variation [887]
MOB2 OTMBE0NS Limited Genetic Variation [888]
MOK OTQK7M9V Limited Biomarker [281]
MPI OTBH6ZK1 Limited Biomarker [723]
MRAS OTNCVCQW Limited Biomarker [73]
MRS2 OTICD11V Limited Genetic Variation [693]
MSH5 OTDARQT3 Limited Biomarker [889]
MSX2 OT1WDKE1 Limited Biomarker [890]
MT1B OTUA4FFH Limited Altered Expression [759]
MT1F OTZVUYG1 Limited Altered Expression [759]
MT1G OTAV1OCR Limited Altered Expression [759]
MT1H OT0MVBM6 Limited Altered Expression [759]
MT1M OTVT8PLU Limited Altered Expression [759]
MTPN OT5N60RU Limited Altered Expression [891]
MYH9 OT94Z706 Limited Biomarker [892]
MYL2 OT78PC0C Limited Genetic Variation [893]
MYLIP OTL0PFGV Limited Biomarker [878]
ND5 OT45LW1K Limited Biomarker [99]
NDUFA12 OTCD6I5M Limited Altered Expression [99]
NEGR1 OT57ECW9 Limited Genetic Variation [894]
NEIL1 OTHBU5DJ Limited Genetic Variation [895]
NEIL3 OTBCI2NS Limited Genetic Variation [845]
NFATC1 OT4TMERS Limited Altered Expression [896]
NIF3L1 OT4MP90J Limited Genetic Variation [122]
NKX6-1 OT5QC0BF Limited Biomarker [144]
NLRP6 OTEREN4W Limited Biomarker [897]
NOL3 OT1K0L0D Limited Altered Expression [767]
NR2C2 OTDZWVOJ Limited Genetic Variation [898]
NR2E1 OTW47GKM Limited Altered Expression [899]
NSA2 OTRU5QPO Limited Biomarker [900]
NSD2 OTQ6SW4R Limited Biomarker [901]
NUCB2 OTHO6JWN Limited Biomarker [338]
NUS1 OT4DQ82L Limited Biomarker [113]
P4HB OTTYNYPF Limited Altered Expression [176]
PADI1 OT13WAQX Limited Altered Expression [176]
PAX6 OTOC9876 Limited Genetic Variation [902]
PCDH8 OTDDOQM2 Limited Biomarker [903]
PCLO OTXJZZ98 Limited Genetic Variation [904]
PDC OT1UUVYY Limited Genetic Variation [905]
PDIA2 OTC2WMXS Limited Altered Expression [176]
PELI1 OTMLBCLC Limited Genetic Variation [906]
PES1 OTMZK7XE Limited Biomarker [900]
PFDN2 OTUYWQ4Z Limited Biomarker [907]
PIK3C2A OTFBU4GD Limited Altered Expression [908]
PITPNC1 OT64TTGC Limited Altered Expression [161]
PIWIL1 OT7CRGZ3 Limited Biomarker [909]
PIWIL4 OTDA9MY0 Limited Biomarker [909]
PLA2G10 OTRZ2L5A Limited Genetic Variation [278]
PLEK OTB73XXA Limited Biomarker [910]
PLEKHG5 OTL0S21W Limited Genetic Variation [226]
POTEM OT7L2HGH Limited Genetic Variation [55]
POU2F1 OTK7ELJ0 Limited Genetic Variation [911]
POU2F2 OTPV0J0C Limited Genetic Variation [912]
POU3F1 OTYARA94 Limited Biomarker [207]
POU5F1 OTDHHN7O Limited Genetic Variation [73]
PPP1R2 OTNLOUQR Limited Biomarker [913]
PRC1 OTHD0XS0 Limited Genetic Variation [113]
PRDM6 OTKY12D9 Limited Genetic Variation [906]
PRDX1 OTZ3BEC4 Limited Altered Expression [914]
PRKAA1 OT7TNF0L Limited Biomarker [915]
PROCR OTRHED17 Limited Altered Expression [916]
PROX1 OT68R6IO Limited Genetic Variation [917]
PRPF31 OTSJ0Z1Y Limited Genetic Variation [918]
PRR5L OTQ1Z0OU Limited Genetic Variation [820]
PRRC2A OTBX6FM5 Limited Genetic Variation [919]
PSG2 OT2EIXAI Limited Altered Expression [88]
PSMA6 OTJ6RPX5 Limited Genetic Variation [920]
PSMD3 OT585WY8 Limited Genetic Variation [921]
PTF1A OT7SWA57 Limited Genetic Variation [551]
PTMA OT2W4T1M Limited Biomarker [922]
PTPRD OTZPJ3GX Limited Biomarker [923]
PTPRT OTV5TXNN Limited Genetic Variation [192]
RANGAP1 OTZGD3LJ Limited Genetic Variation [924]
RAPGEF1 OTZ0TBN1 Limited Genetic Variation [925]
RASD1 OT2BAJHK Limited Biomarker [926]
RASGRP1 OTX9WN2E Limited Genetic Variation [113]
RBMS1 OTD13PJN Limited Genetic Variation [308]
RELA OTUJP9CN Limited Altered Expression [927]
REM1 OTUXL0HC Limited Genetic Variation [928]
REV3L OT0OP8EJ Limited Genetic Variation [929]
RHOT1 OTBIRR8Q Limited Biomarker [930]
RIT2 OTSNYG0D Limited Biomarker [931]
RNASEK OT1QS1KM Limited Biomarker [932]
RNF10 OTF7Y6M7 Limited Genetic Variation [714]
RP9 OTGQY66H Limited Altered Expression [933]
RPE OT0XT3JU Limited Biomarker [934]
RPL29 OTUFIBJL Limited Biomarker [280]
RPN2 OTJ1SKOA Limited Genetic Variation [533]
RYR2 OT0PF19E Limited Biomarker [935]
SAA2 OTYAVJWG Limited Biomarker [198]
SAGE1 OT4H6FFA Limited Biomarker [936]
SAMD12 OTIFG9O6 Limited Biomarker [937]
SBNO2 OT1C6J3K Limited Genetic Variation [820]
SCO1 OTC45UGB Limited Biomarker [938]
SCTR OTC80IMR Limited Biomarker [113]
SDHA OTOJ8QFF Limited Biomarker [99]
SEPTIN5 OT6JTJBO Limited Biomarker [939]
SERP1 OT60XXUP Limited Biomarker [940]
SESN1 OTSFDZWL Limited Altered Expression [941]
SESN3 OTJRY1Y5 Limited Altered Expression [941]
SGMS2 OT3NHO99 Limited Biomarker [942]
SIGLEC5 OTYC440J Limited Altered Expression [943]
SKIL OTNBXH32 Limited Biomarker [214]
SMAD5 OTQNSVCQ Limited Therapeutic [944]
SORL1 OTQ8FFNS Limited Biomarker [945]
SOX6 OTT0W0LE Limited Genetic Variation [946]
SPON2 OTE7JLNM Limited Biomarker [947]
SPX OTY3G4AR Limited Biomarker [948]
ST13 OTNML6UP Limited Biomarker [280]
ST6GAL1 OT7US3NO Limited Genetic Variation [113]
STAP2 OTEB1VVI Limited Genetic Variation [949]
STEAP4 OTFTLAEZ Limited Altered Expression [950]
STN1 OT8UWRA3 Limited Genetic Variation [951]
STX1A OTSBUZB4 Limited Biomarker [952]
STX5 OTQ0024B Limited Biomarker [953]
STXBP3 OTTTYMAQ Limited Biomarker [954]
STXBP5L OTNXAUKD Limited Biomarker [955]
SYT11 OTLRTZEI Limited Altered Expression [956]
SYT4 OTA1D7VL Limited Altered Expression [956]
TADA1 OTV9RKSL Limited Biomarker [957]
TAF1 OTDYS5G4 Limited Biomarker [875]
TAL1 OTX4K6QZ Limited Biomarker [725]
TAS1R2 OT53VYMN Limited Altered Expression [958]
TAS1R3 OTOVM44D Limited Altered Expression [958]
TAS2R13 OTSTOX5G Limited Genetic Variation [959]
TCF19 OT7NKLF9 Limited Genetic Variation [528]
TCP1 OT1MGUX9 Limited Genetic Variation [746]
TENM4 OT91K3FC Limited Genetic Variation [960]
TGM2 OT6MFOWF Limited Autosomal dominant [727]
THADA OTYZQX0F Limited Altered Expression [961]
THBS2 OTXET551 Limited Genetic Variation [962]
THEM4 OTSIZU8Y Limited Genetic Variation [963]
THRAP3 OTG25JOG Limited Biomarker [964]
TJP1 OTBDCUPK Limited Biomarker [965]
TJP2 OTQUY6BV Limited Biomarker [966]
TLE3 OTR9PH95 Limited Biomarker [967]
TLL1 OTK9NM7G Limited Biomarker [968]
TM7SF2 OTILU5S7 Limited Biomarker [314]
TMEM11 OTL9HDEY Limited Biomarker [723]
TNFAIP8L2 OTII0RM0 Limited Biomarker [969]
TOMM40 OTZDQ29F Limited Biomarker [970]
TOMM5 OTKXOH4K Limited Altered Expression [971]
TOX OTE8BL5Z Limited Biomarker [972]
TRAF3 OT5TQBGV Limited Genetic Variation [973]
TRAM1 OT3I0H8E Limited Biomarker [228]
TREH OTJE0NOY Limited Altered Expression [974]
TSHZ1 OTYQ9ECW Limited Altered Expression [975]
ARIH1 OTO3XDR2 Disputed Biomarker [976]
ASAH2 OT47TIF3 Disputed Biomarker [977]
ATP8 OTYQQR53 Disputed Genetic Variation [978]
BANF1 OTP7Z38L Disputed Biomarker [241]
BPIFA1 OTQFD2J5 Disputed Biomarker [979]
BRINP3 OT4VFHWN Disputed Altered Expression [980]
CFHR2 OTACE5Y1 Disputed Biomarker [981]
CKB OTUCKOTT Disputed Genetic Variation [982]
COL4A5 OTHG60RE Disputed Biomarker [983]
CTCF OT8ZB70U Disputed Biomarker [984]
DDT OTF5HTYL Disputed Genetic Variation [487]
DMP1 OTBWBWW7 Disputed Biomarker [985]
ESM1 OT331Y8V Disputed Biomarker [986]
FAM3C OTBR6U9G Disputed Altered Expression [987]
FRMD3 OT0CD2GG Disputed Biomarker [988]
GALP OTW25XLK Disputed Biomarker [989]
GATA6 OTO2BC0F Disputed Biomarker [990]
IFI30 OT9DERT1 Disputed Genetic Variation [991]
JRK OTO8E77P Disputed Biomarker [248]
KIFBP OT1XADKG Disputed Biomarker [992]
KPNA1 OTEMVAJ6 Disputed Genetic Variation [993]
MARK4 OT6Z2TGV Disputed Biomarker [994]
MED19 OTT9RT5N Disputed Genetic Variation [995]
NBAS OTW9IBRI Disputed Biomarker [245]
OMG OTXA5C6L Disputed Biomarker [996]
PAGE1 OT7SQGM8 Disputed Biomarker [997]
PCOLCE OTJXOAN4 Disputed Biomarker [998]
PIK3C3 OTLUM9L7 Disputed Biomarker [999]
PMAIP1 OTXEE550 Disputed Biomarker [1000]
RAB27A OT9SQRWY Disputed Altered Expression [1001]
REG1A OTMHUH1D Disputed Genetic Variation [1002]
RFC2 OTJ9N6BD Disputed Biomarker [1003]
SART3 OTC1AM7S Disputed Biomarker [1004]
SCN7A OTK05PXY Disputed Biomarker [245]
SIT1 OT7MDF09 Disputed Genetic Variation [1005]
STARD10 OTWVNFV4 Disputed Genetic Variation [1006]
ACACA OT5CQPZY moderate Genetic Variation [774]
AFM OTPOR8IO moderate Altered Expression [1007]
AHSA1 OTC7AFHT moderate Biomarker [166]
ANGPTL5 OTC6AFVO moderate Altered Expression [1008]
ARAP1 OTINOJJ7 moderate Genetic Variation [113]
C2CD4A OTUKXHNG moderate Genetic Variation [1009]
CCN3 OTOW5YL4 moderate Altered Expression [1010]
CCND2 OTDULQF9 moderate Genetic Variation [178]
CD300C OT4BSR7D moderate Biomarker [1011]
CD5L OTPY4WQR moderate Biomarker [269]
CFAP97 OT0RSQO4 moderate Biomarker [1012]
CISD3 OT0MM1MW moderate Biomarker [799]
CNDP2 OTJR9436 moderate Genetic Variation [1013]
CXCL14 OTM189TA moderate Biomarker [1014]
CXCL16 OTD49T9R moderate Biomarker [515]
DDAH2 OT8Q40G2 moderate Genetic Variation [1015]
DGKD OTNI8HAH moderate Genetic Variation [113]
DIO2 OTGPNSLH moderate Genetic Variation [1016]
FXYD5 OT81DIOD moderate Biomarker [1017]
GABPB1 OTEXDEJN moderate Genetic Variation [1018]
GC OTWS63BY moderate Posttranslational Modification [1019]
GPC5 OT8NR7GC moderate Biomarker [1020]
GPR151 OT7EACU6 moderate Biomarker [266]
GRAP2 OTS5NIZ3 moderate Biomarker [166]
GSTK1 OTDNGWAF moderate Genetic Variation [697]
HSPA2 OTSDET7B moderate Genetic Variation [1021]
IRS4 OTTOL40K moderate Genetic Variation [1022]
MAFA OTBCA105 moderate Altered Expression [1023]
MAP6 OTPUI00F moderate Genetic Variation [1024]
NTS OTPGDNQS moderate Biomarker [1025]
OGA OT7ZBWT1 moderate Altered Expression [1026]
OGN OTKP5S4L moderate Biomarker [1027]
PGP OT6QQ7OR moderate Genetic Variation [264]
PHLPP1 OTIFXW8D moderate Biomarker [1028]
PIK3R1 OT5BZ1J9 moderate Genetic Variation [1029]
PLEKHA1 OT66PF24 moderate Genetic Variation [113]
PODXL OTPNQXF3 moderate Altered Expression [1030]
PSMD6 OTX59EGK moderate Genetic Variation [113]
RGCC OTYJMLWM moderate Altered Expression [1031]
RNF19A OTKWCV80 moderate Biomarker [166]
RPL14 OTZZW7TK moderate Genetic Variation [1032]
RTN1 OTCX1SMK moderate Genetic Variation [1033]
SELENOP OT02B8IR moderate Altered Expression [848]
SERPINB2 OT72QLZB moderate Biomarker [1034]
SFRP5 OTLCVVSH moderate Biomarker [659]
SOD3 OTIOZQAB moderate Biomarker [1035]
SOX13 OTCIF6KC moderate Biomarker [1036]
SPESP1 OTWXKKTJ moderate Genetic Variation [1037]
TAC3 OTOJGM38 moderate Biomarker [1038]
TCF4 OTB9ASTK moderate Biomarker [1039]
TET3 OT76U3YF moderate Altered Expression [1040]
THBS4 OTA1T9KK moderate Altered Expression [1041]
TIMD4 OTGGC20G moderate Biomarker [1042]
TMEM18 OT05YQ1E moderate Genetic Variation [1043]
AAAS OTJT9T23 Strong Genetic Variation [1044]
AANAT OTUBJ7SX Strong Biomarker [493]
ABCB10 OT1C44F9 Strong Genetic Variation [178]
ABI3BP OTW8DN50 Strong Genetic Variation [418]
ACAD10 OTFAG3M0 Strong Biomarker [1045]
ACVR1C OTOTYERF Strong Genetic Variation [1046]
ADA2 OTGCV24S Strong Genetic Variation [304]
ADAM11 OTPTVW5W Strong Biomarker [349]
ADAM19 OTH88TXU Strong Altered Expression [1047]
ADAM28 OT3GBVHL Strong Biomarker [1048]
ADAMTS2 OTTK22NO Strong Genetic Variation [1049]
ADAMTS9 OTV3Q0DS Strong Biomarker [1050]
ADARB1 OTGKSZEV Strong Genetic Variation [1051]
ADCY3 OTGOQM6B Strong Genetic Variation [1052]
ADIPOR1 OT65ZFZN Strong Altered Expression [316]
AGXT2 OTO6QUTM Strong Altered Expression [1053]
AIM2 OT86QUI8 Strong Biomarker [1054]
AK1 OT614AR3 Strong Biomarker [1055]
AKAP6 OTN59BZS Strong Genetic Variation [1056]
AKTIP OT78TJID Strong Genetic Variation [178]
ALDOB OT7FR69A Strong Biomarker [1057]
ALX4 OTNS9A29 Strong Genetic Variation [1058]
AMY1A OT6G4B8O Strong Biomarker [497]
ANGPTL2 OTB6JG41 Strong Biomarker [1059]
ANKFY1 OTHT028D Strong Genetic Variation [178]
ANKH OTCN25R5 Strong Genetic Variation [178]
ANKRD23 OT0LX681 Strong Biomarker [1060]
ANKRD55 OT62KZII Strong Genetic Variation [1061]
ANXA6 OT9KIQ0Y Strong Biomarker [1062]
APOD OTT77XW8 Strong Genetic Variation [1063]
AQP11 OT1IQMHV Strong Genetic Variation [1064]
ARHGAP15 OT9CKHDC Strong Genetic Variation [1065]
ARHGAP22 OTXUQEFL Strong Altered Expression [1066]
ARID1B OTILK3Q7 Strong Biomarker [1067]
ARID3A OTZZ4SFP Strong Biomarker [1067]
ARID4B OTYLPILE Strong Biomarker [1068]
ARL15 OT00YSWZ Strong Genetic Variation [1069]
ARL9 OTCP868V Strong Genetic Variation [418]
ARNT OTMSIEZY Strong Altered Expression [1070]
ARSL OTF1VTCR Strong Biomarker [1071]
ARX OTBGYH25 Strong Biomarker [1072]
ASB3 OTI3TK38 Strong Genetic Variation [409]
ASCC2 OT3B204T Strong Genetic Variation [528]
ASCL2 OT3D62WB Strong Genetic Variation [113]
ATF7IP OTU6ZA7F Strong Biomarker [1073]
ATP2A1 OT959A3A Strong Biomarker [580]
ATP5F1B OTLFZUQK Strong Biomarker [1074]
ATP5PF OTDAE8FP Strong Biomarker [1075]
ATP6AP2 OT0IABVV Strong Biomarker [1076]
ATP6V1H OTX17GQ9 Strong Biomarker [1077]
ATP8B2 OTH5WJ09 Strong Genetic Variation [113]
ATXN7 OTL3YF1H Strong Genetic Variation [178]
BAD OT63ERYM Strong Biomarker [346]
BBS10 OTL1TTWX Strong Genetic Variation [1078]
BCL9 OTRBIPR4 Strong Genetic Variation [409]
BCR OTCN76C1 Strong Biomarker [1079]
BCS1L OT5PY5CY Strong Biomarker [1080]
BEST1 OTWHE1ZC Strong Altered Expression [261]
BEST3 OTMY8G20 Strong Genetic Variation [409]
BFAR OTTBG0V7 Strong Genetic Variation [1081]
BICC1 OTYRKIJ1 Strong Genetic Variation [409]
BID OTOSHSHU Strong Biomarker [1082]
BNIP3 OT4SO7J4 Strong Altered Expression [592]
C16orf74 OTLLVHH0 Strong Genetic Variation [1083]
C17orf58 OT6RG1OZ Strong Genetic Variation [528]
C1GALT1 OT2ZSZ6P Strong Genetic Variation [178]
C1QL3 OT4TZH3J Strong Biomarker [1084]
C1QTNF1 OT7I7KHC Strong Biomarker [660]
C1QTNF12 OTFAIQHR Strong Biomarker [660]
C1QTNF3 OTOJMWW0 Strong Altered Expression [1085]
C2CD4B OTCLQ6NZ Strong Genetic Variation [1009]
C5AR2 OTP1Q82J Strong Genetic Variation [1086]
C7orf50 OTDHN459 Strong Genetic Variation [1087]
CALCOCO2 OTRGX0OV Strong Genetic Variation [528]
CAMK2A OTJGX19T Strong Altered Expression [1088]
CAMK2N1 OTKCR5XL Strong Altered Expression [1089]
CAMTA1 OTAN1S5B Strong Genetic Variation [1090]
CAND2 OTOMOG3R Strong Biomarker [1091]
CAPN3 OTCHG3YK Strong Biomarker [1092]
CARTPT OTTE4V9S Strong Biomarker [1093]
CASP12 OTY2W6FG Strong Biomarker [346]
CAV3 OTWSFDB4 Strong Genetic Variation [1094]
CCDC149 OT7S7MU9 Strong Genetic Variation [409]
CCHCR1 OT22C116 Strong Biomarker [1095]
CCL16 OTOOQI1F Strong Genetic Variation [1096]
CCL28 OTY6XNQ7 Strong Genetic Variation [1097]
CCN4 OT69BER9 Strong Biomarker [1098]
CCNL1 OTAJSS3D Strong Genetic Variation [1099]
CCNQ OT183N7L Strong Genetic Variation [1100]
CCRL2 OT5PX0RX Strong Altered Expression [1101]
CD81 OTQFXNAZ Strong Genetic Variation [1102]
CDC42 OT5QBC5M Strong Biomarker [1103]
CELA3A OT9JAL80 Strong Biomarker [360]
CELSR1 OT7PS8O1 Strong Genetic Variation [409]
CENPJ OTZCQZN5 Strong Biomarker [1104]
CENPX OTG1RAKJ Strong Biomarker [1105]
CEP55 OTGSG2PA Strong Biomarker [1106]
CEP68 OTZDM4J1 Strong Genetic Variation [528]
CERS6 OTOP4GV1 Strong Genetic Variation [1107]
CFAP77 OTIIEG6E Strong Genetic Variation [366]
CHCHD6 OT8F9BHW Strong Genetic Variation [310]
CHD8 OTS7A6AF Strong Genetic Variation [1108]
CHPT1 OT4FJ0K3 Strong Genetic Variation [1109]
CIB1 OT4BVCRU Strong Biomarker [82]
CIDEC OTMDZ56K Strong Biomarker [1110]
CISD1 OT0MTVGF Strong Biomarker [1111]
CITED2 OT812TV7 Strong Altered Expression [1112]
CKM OTME0KO7 Strong Genetic Variation [1113]
CLN8 OT0D4CB5 Strong Genetic Variation [409]
CNBP OTTGM9NK Strong Genetic Variation [1114]
COL3A1 OTT1EMLM Strong Biomarker [1115]
COL9A1 OTWBR27Y Strong Genetic Variation [560]
COL9A2 OT1ZBDBV Strong Genetic Variation [560]
COL9A3 OTCUJOEK Strong Genetic Variation [560]
COPA OTZ1DTXU Strong Biomarker [1116]
COX2 OTTMVBJJ Strong Biomarker [436]
COX4I1 OTU0FC24 Strong Biomarker [99]
CPEB3 OTP1GQCH Strong Genetic Variation [612]
CPED1 OTJJPZOZ Strong Genetic Variation [1051]
CPLX1 OT7UIGTP Strong Genetic Variation [1117]
CPT1A OTI862QH Strong Genetic Variation [1087]
CPT2 OTIN6G20 Strong Biomarker [1118]
CRISP2 OT8HLTV5 Strong Altered Expression [1119]
CRISPLD2 OTVSFHTL Strong Biomarker [1120]
CST2 OTRKRW50 Strong Altered Expression [1121]
CST3 OTNZ6AO4 Strong Biomarker [1122]
CST7 OTQWZUVQ Strong Biomarker [1123]
CTBP1 OTVYH2DH Strong Biomarker [1124]
CTRB1 OTFFF738 Strong Biomarker [551]
CTTNBP2 OT4CL1EW Strong Genetic Variation [366]
CXCL5 OTZOUPCA Strong Altered Expression [1125]
CYB5D2 OTX10KKR Strong Genetic Variation [178]
CYB5R4 OTF552H6 Strong Biomarker [1126]
CYP4V2 OTQKNK0D Strong Altered Expression [1127]
CYRIB OTLRN4L1 Strong Biomarker [1091]
CYTB OTAHB98A Strong Biomarker [1128]
DAPK2 OTWODUQG Strong Biomarker [1129]
DARS1 OT0WGC2T Strong Genetic Variation [409]
DARS2 OTVPFTBG Strong Genetic Variation [1065]
DBNL OTT2OQOV Strong Biomarker [1123]
DCTN4 OTM7C943 Strong Altered Expression [216]
DCX OTISR7K3 Strong Biomarker [1130]
DDIT3 OTI8YKKE Strong Altered Expression [477]
DDX3X OTDO4TRX Strong Altered Expression [1131]
DECR1 OTCDIR6X Strong Biomarker [1132]
DEFB1 OT5SV0E4 Strong Genetic Variation [1133]
DENR OTXP9HOY Strong Biomarker [1129]
DEPDC5 OTE70JLY Strong Genetic Variation [1051]
DESI1 OTFNIW98 Strong Biomarker [1134]
DHDDS OTVLYBUS Strong Genetic Variation [1109]
DHDH OTKA2AL6 Strong Biomarker [1135]
DHX40 OTOL02QN Strong Biomarker [1136]
DIAPH2 OTBEYFEZ Strong Genetic Variation [473]
DLD OT378CU9 Strong Biomarker [1137]
DLEU7 OTVKX1YP Strong Genetic Variation [366]
DMRTA1 OTRZY9E9 Strong Biomarker [1138]
DNAJB3 OTODJZY9 Strong Biomarker [1139]
DNAJC27 OTJRPCUR Strong Altered Expression [1140]
DNER OT2GH2E5 Strong Biomarker [1141]
DNM1L OTXK1Q1G Strong Biomarker [1129]
DOCK4 OTH3XY8B Strong Genetic Variation [178]
DOK5 OT2XWUPN Strong Biomarker [1142]
DPPA3 OTS7N4Q9 Strong Genetic Variation [1143]
DPYS OTLTUIVL Strong Biomarker [1144]
DSEL OTVNQD3I Strong Genetic Variation [480]
DST OTHZBM4X Strong Genetic Variation [1145]
DUOX1 OTQ2AEW0 Strong Biomarker [697]
DUOX2 OTU14HCN Strong Biomarker [697]
DUSP12 OT8WB1YB Strong Genetic Variation [1146]
DUSP26 OTI7WIYN Strong Biomarker [1147]
EDARADD OT0G52MC Strong Genetic Variation [409]
EIF3F OTU20K6L Strong Biomarker [1148]
EIF3K OTGTKVGO Strong Altered Expression [1149]
EIF5B OTZTT22W Strong Biomarker [1135]
ELAVL2 OT6EJ8MQ Strong Genetic Variation [1150]
ELN OTFSO7PG Strong Biomarker [1151]
ELOVL6 OTB26UJJ Strong Genetic Variation [1152]
ENHO OT91QASK Strong Genetic Variation [1153]
ERFE OTSES1HA Strong Altered Expression [780]
ERP44 OT7ZI7AG Strong Biomarker [1154]
ERRFI1 OT7VZ2IZ Strong Genetic Variation [1155]
ETV3 OTEN03BM Strong Biomarker [1156]
EVC OTRVYMXJ Strong Genetic Variation [1157]
EXOC6 OTVVD62X Strong Genetic Variation [1083]
EXOSC4 OTG4TICP Strong Biomarker [1158]
EXT1 OTRPALJK Strong Genetic Variation [1159]
FABP6 OTIRQWLW Strong Genetic Variation [1160]
FAIM2 OT6QINVO Strong Genetic Variation [1161]
FAM3D OTM3GWFP Strong Biomarker [1162]
FBL OTRODIE5 Strong Genetic Variation [239]
FBLIM1 OTFHXMON Strong Biomarker [594]
FBN2 OT3KYJQL Strong Genetic Variation [774]
FBP1 OTQBANEP Strong Biomarker [413]
FBXL7 OTNUK1DJ Strong Genetic Variation [409]
FCGR3B OTSLSPZG Strong Altered Expression [351]
FCHSD2 OTKXLIJ6 Strong Genetic Variation [1163]
FCN3 OTPRENLS Strong Biomarker [1164]
FEM1B OTFE2ELA Strong Biomarker [1165]
FETUB OT7V07NI Strong Altered Expression [1166]
FGF11 OT6513W2 Strong Biomarker [1167]
FGL1 OTT0QHQ1 Strong Biomarker [1168]
FNDC4 OTOQK0WK Strong Biomarker [1169]
FNDC5 OT5CSK9X Strong Biomarker [1170]
FOXD3 OTXYV6GO Strong Biomarker [1171]
FOXO3 OTHXQG4P Strong Altered Expression [1172]
FRY OT74IAG2 Strong Genetic Variation [418]
FSCN3 OTVOL6GA Strong Genetic Variation [1083]
FSD1 OT8P6PT3 Strong Biomarker [1173]
FSD1L OTBQ48RF Strong Biomarker [1173]
FUBP1 OT77SC9N Strong Biomarker [413]
FZD4 OTGLZIE0 Strong Biomarker [266]
GABRA4 OT5I7OI2 Strong Genetic Variation [1174]
GBP2 OTVU4G07 Strong Biomarker [1175]
GCA OTAJ7ZHG Strong Biomarker [750]
GCC1 OTDOE6U8 Strong Genetic Variation [1176]
GDAP1L1 OT9IEBRD Strong Genetic Variation [1177]
GDF11 OTOSNMND Strong Altered Expression [1178]
GFER OTVK43OK Strong Biomarker [733]
GGA3 OTXZ2W65 Strong Genetic Variation [1157]
GGTLC1 OTWJKUHQ Strong Biomarker [1179]
GIN1 OT6L79OO Strong Genetic Variation [178]
GLIS3 OTBC960E Strong Genetic Variation [113]
GOPC OTRBGH71 Strong Biomarker [594]
GORASP2 OTL3PLD2 Strong Biomarker [1180]
GOT2 OT6XBWN0 Strong Genetic Variation [1181]
GPC4 OTUJ14DW Strong Biomarker [1182]
GPR142 OT6UFQCL Strong Biomarker [1183]
GPR42 OTEB0ROY Strong Biomarker [299]
GPRC5B OTF3S5E3 Strong Biomarker [1184]
GPS2 OT065FSS Strong Biomarker [1185]
GPSM1 OTA0SJBG Strong Genetic Variation [113]
GPT2 OTS5VF7N Strong Biomarker [1186]
GRB10 OTCKXGRC Strong Biomarker [1187]
GTF2H1 OTCRXC6B Strong Altered Expression [216]
GTF3A OTVROUVQ Strong Biomarker [1188]
HARS1 OTHOEOTS Strong Biomarker [1189]
HAVCR1 OT184CRZ Strong Biomarker [1190]
HCCS OTQE88BE Strong Genetic Variation [1191]
HEMGN OTZPYUOY Strong Genetic Variation [593]
HGS OTCYYCAC Strong Biomarker [1189]
HHIP OT77RQYS Strong Biomarker [280]
HIVEP2 OTVOMCW4 Strong Genetic Variation [178]
HLA-DOB OTKADDUB Strong Genetic Variation [366]
HLA-DRA OT7KZMP2 Strong Altered Expression [1192]
HNRNPK OTNPRM8U Strong Altered Expression [1131]
HOOK2 OTPO4NQV Strong Posttranslational Modification [1193]
HORMAD1 OT7DR5T2 Strong Biomarker [1194]
HORMAD2 OTL2ENWI Strong Genetic Variation [366]
HSPA1A OTKGIE76 Strong Altered Expression [1195]
HSPA4 OT5HR0AR Strong Genetic Variation [1196]
HTN1 OTH3W1RR Strong Biomarker [181]
IGFBP4 OT2HZRBD Strong Biomarker [1197]
IL17REL OT0PG9GU Strong Genetic Variation [581]
IL18R1 OT83XMPQ Strong Biomarker [387]
IL3 OT0CQ35N Strong Altered Expression [1198]
IL6ST OT1N9C70 Strong Biomarker [368]
INPPL1 OTCDAVBQ Strong Biomarker [1199]
INSRR OT3F75WA Strong Genetic Variation [1200]
INTS8 OT3SRRLM Strong Genetic Variation [1201]
INTU OTXB13E6 Strong Genetic Variation [1202]
ISG20 OTCWRJJW Strong Biomarker [1203]
ISL1 OTVNVKAX Strong Altered Expression [1204]
ITGA2B OT4Y17PY Strong Genetic Variation [1205]
ITGAX OTOGIMHE Strong Altered Expression [515]
ITGB1BP1 OTVQFNGS Strong Altered Expression [1206]
ITLN1 OT7ZLJVV Strong Biomarker [1207]
IVNS1ABP OTYHL4I7 Strong Genetic Variation [1208]
KCNIP1 OTGLGK1R Strong Biomarker [1209]
KCNJ15 OTZT6EQB Strong Genetic Variation [1210]
KCNMB1 OTO4KNJ4 Strong Biomarker [1211]
KCTD1 OT89U5MB Strong Biomarker [1212]
KHSRP OTDHZARB Strong Altered Expression [1213]
KIF6 OTDH3MR4 Strong Genetic Variation [1214]
KIF9 OT7W6VI1 Strong Genetic Variation [528]
KL OTD4VWU6 Strong Biomarker [1215]
KLF10 OT4F4UGS Strong Altered Expression [1216]
KLF14 OT8BXLBS Strong Altered Expression [1217]
KLHL3 OTEJ6850 Strong Biomarker [1218]
KLHL42 OTK6WARI Strong Genetic Variation [1061]
KMT2D OTTVHCLY Strong Biomarker [733]
KRT18 OTVLQFIP Strong Biomarker [1219]
KSR2 OTSMUL59 Strong Genetic Variation [113]
LAD1 OT6YGTVX Strong Biomarker [1220]
LCN1 OT8BWXTV Strong Biomarker [1221]
LECT2 OTSFZ9JD Strong Altered Expression [1222]
LGR6 OTPZ1PWR Strong Biomarker [266]
LINGO2 OT3N88Q1 Strong Genetic Variation [1223]
LIPC OTZY5SC9 Strong Biomarker [1224]
LITAF OTT5JX1F Strong Genetic Variation [1225]
LRFN2 OTI2QPM2 Strong Genetic Variation [409]
LRG1 OTLD0KWA Strong Biomarker [1226]
LRMDA OTIPNKTU Strong Genetic Variation [113]
LRP12 OTRT1UJ7 Strong Genetic Variation [581]
LRP1B OT4YZG2N Strong Genetic Variation [418]
LRPPRC OTXSK5LP Strong Biomarker [368]
LSR OTR8Y32X Strong Biomarker [1227]
MACF1 OTVIHD77 Strong Genetic Variation [528]
MAGEC3 OT0KDWZN Strong Genetic Variation [1051]
MAGEE1 OTOQQO2X Strong Genetic Variation [1228]
MAGI2 OTXDDKZS Strong Genetic Variation [418]
MAP1LC3A OTPMGIU4 Strong Therapeutic [1229]
MAP4K5 OTUFGLXE Strong Biomarker [1230]
MBNL1 OTOV7J85 Strong Genetic Variation [366]
MBOAT7 OTHRCBLK Strong Genetic Variation [1231]
MCC OTQVI1EM Strong Genetic Variation [581]
MCIDAS OTK1JVAH Strong Biomarker [1232]
MED23 OTKZQT0R Strong Genetic Variation [366]
MED25 OTDBY87B Strong Biomarker [1233]
MEF2A OTV2SF6E Strong Genetic Variation [1234]
MEFV OTRJ6S6K Strong Altered Expression [1235]
METRNL OTB0DDL0 Strong Altered Expression [1236]
METTL3 OTSXP1M3 Strong Altered Expression [1237]
METTL9 OT3YR9B2 Strong Altered Expression [933]
MFAP1 OTZN4FT3 Strong Altered Expression [734]
MFAP2 OTMHVBTV Strong Biomarker [461]
MFN2 OTPYN8A3 Strong Biomarker [1129]
MFRP OTHY9ZA5 Strong Altered Expression [1085]
MICA OTPEIEAR Strong Genetic Variation [1238]
MINDY1 OTVLF4G5 Strong Genetic Variation [528]
MIXL1 OT584VOQ Strong Biomarker [1239]
MLX OTZ74KFI Strong Genetic Variation [528]
MLXIPL OTR9MLLW Strong Biomarker [1240]
MMAB OTOWOEJN Strong Biomarker [1241]
MNX1 OTXP9FH1 Strong Genetic Variation [113]
MPHOSPH10 OT8DJTO7 Strong Biomarker [464]
MPST OTCDPH5D Strong Biomarker [1055]
MRGPRX3 OTRKCCDS Strong Biomarker [266]
MRGPRX4 OTOBHZVA Strong Biomarker [266]
MRPL12 OTU41AM0 Strong Genetic Variation [409]
MRPS35 OT8GFX5T Strong Genetic Variation [528]
MSH3 OTD3YPVL Strong Genetic Variation [409]
MT1E OTXJKU4Y Strong Altered Expression [1242]
MT1X OT9AKFVS Strong Altered Expression [1242]
MTHFD1 OTMKHVWC Strong Genetic Variation [186]
MTMR3 OTBIT23O Strong Genetic Variation [528]
MTMR7 OT47NVYM Strong Altered Expression [1243]
MTSS1 OT5DTDO2 Strong Genetic Variation [418]
MUC19 OTM06UGV Strong Genetic Variation [1244]
MYO5A OTMWLP3E Strong Altered Expression [702]
NANS OTMQ2FUH Strong Genetic Variation [1245]
NBEAL2 OTMCAXWR Strong Biomarker [1246]
NCOA5 OTOGWTWB Strong Genetic Variation [1247]
NCOA6 OTOMIGTV Strong Biomarker [1248]
NCOR1 OT04XNOU Strong Biomarker [1249]
NCOR2 OTY917X0 Strong Genetic Variation [1250]
NCS1 OT6JHAWM Strong Biomarker [1251]
ND1 OTCLGIXV Strong Genetic Variation [1252]
NDUFAF6 OTRJMIGT Strong Genetic Variation [178]
NDUFS4 OTJKUYEE Strong Biomarker [1253]
NECTIN2 OTIE0W6O Strong Genetic Variation [1254]
NFAT5 OTKIE59S Strong Genetic Variation [178]
NFATC2 OTK5T6HZ Strong Genetic Variation [113]
NFE2L1 OT1QHOS2 Strong Biomarker [1234]
NFKBIL1 OTYFTPS0 Strong Genetic Variation [366]
NFYA OTWFFOVH Strong Genetic Variation [1255]
NFYB OTXSE7KW Strong Altered Expression [1255]
NFYC OTZVVEV7 Strong Biomarker [1255]
NHS OTKE8QAT Strong Genetic Variation [1256]
NIPA2 OT4NEBNO Strong Biomarker [1257]
NLGN1 OTGHRRFQ Strong Genetic Variation [409]
NOG OTGRHHPG Strong Biomarker [1258]
NOS1AP OTDFOBRU Strong Biomarker [1259]
NPC1 OTRIPICX Strong Genetic Variation [1260]
NPHS1 OT21JD3P Strong Altered Expression [1261]
NPPA OTMQNTNX Strong Genetic Variation [1262]
NPRL3 OTS4HE8E Strong Genetic Variation [1065]
NPS OTEG25A2 Strong Genetic Variation [1263]
NPTXR OTQJEOIH Strong Biomarker [173]
NRF1 OTOXWNV8 Strong Biomarker [1234]
NRK OTGR01FF Strong Biomarker [1264]
NRL OT65MFKQ Strong Biomarker [1265]
NRXN1 OTJN1JQA Strong Genetic Variation [409]
NRXN3 OTJ0I7HJ Strong Genetic Variation [366]
NSG1 OTRIMA50 Strong Genetic Variation [418]
NT5C3A OT67KZJA Strong Biomarker [1266]
NUDT6 OTCS3NYZ Strong Genetic Variation [366]
NUP62 OTMN63DH Strong Altered Expression [216]
NUPR1 OT4FU8C0 Strong Altered Expression [1267]
OASL OTZ05YRP Strong Genetic Variation [73]
OCA2 OTDWIGBF Strong Biomarker [1268]
OGT OT1Z1ZXE Strong Altered Expression [1269]
OLIG1 OTIMFI31 Strong Altered Expression [484]
OLIG2 OTMCN6D3 Strong Altered Expression [484]
OR10A4 OTYYB8SY Strong Genetic Variation [1270]
OSBPL1A OTQ33OQV Strong Genetic Variation [1271]
OSBPL3 OT9G194Y Strong Genetic Variation [418]
OSBPL7 OTUU2X2Q Strong Genetic Variation [366]
OXCT1 OT536PE7 Strong Biomarker [1272]
P2RX2 OT0LF34A Strong Genetic Variation [517]
P2RX5 OTLBR20R Strong Genetic Variation [517]
P2RX6 OT1FNTXA Strong Genetic Variation [517]
PABPC4 OTICKKBQ Strong Genetic Variation [178]
PALD1 OTLGUM8H Strong Genetic Variation [1051]
PALLD OTZ2MUJZ Strong Genetic Variation [1273]
PANX1 OTXPEDOK Strong Biomarker [1274]
PBX4 OTUWEWSW Strong Genetic Variation [409]
PCBD1 OTDSRUD5 Strong Genetic Variation [1275]
PCNX2 OT90S9W6 Strong Genetic Variation [1276]
PDAP1 OTJSWMOD Strong Altered Expression [933]
PDHB OT2NHE5E Strong Altered Expression [1277]
PDLIM5 OTLQVV22 Strong Genetic Variation [1278]
PDSS2 OTEOQBMX Strong Genetic Variation [418]
PEA15 OTKCKTSX Strong Biomarker [534]
PEG3 OTHQW98S Strong Biomarker [1279]
PELO OTF3WLIM Strong Genetic Variation [113]
PER2 OTU2B1DJ Strong Biomarker [1280]
PER3 OTVKYVJA Strong Genetic Variation [1244]
PEX5L OTLR4HSR Strong Genetic Variation [409]
PFKM OT1QY9JM Strong Biomarker [1281]
PHF6 OT8DXI40 Strong Biomarker [1282]
PHOSPHO1 OT43A0JA Strong Biomarker [1283]
PHOX2A OTVS3R2X Strong Biomarker [1284]
PIEZO2 OTQ7AT38 Strong Genetic Variation [1285]
PIK3C2G OTW3LY1C Strong Genetic Variation [1286]
PITPNM2 OTQXF4FF Strong Genetic Variation [366]
PKNOX1 OTUDMNHX Strong Altered Expression [1287]
PLA2G6 OT5FL0WU Strong Genetic Variation [1288]
PLAG1 OTT9AJQY Strong Biomarker [467]
PLAGL1 OTZAO900 Strong Biomarker [638]
PLCB3 OT0OMDEM Strong Genetic Variation [528]
PLIN2 OTRXJ9UN Strong Altered Expression [1289]
PLXNA2 OTNNBJMQ Strong Biomarker [1290]
PNPLA2 OTR3ERMR Strong Biomarker [1291]
POC5 OTHD4FIH Strong Genetic Variation [1292]
POLDIP2 OT8SZSJ6 Strong Biomarker [166]
PPIG OTZ8BTTM Strong Genetic Variation [1293]
PPIL6 OTOZQMQE Strong Genetic Variation [670]
PPP1R3B OTVCRXEZ Strong Genetic Variation [1294]
PPP1R3C OTEU05TX Strong Biomarker [1295]
PPP2R2C OTXK0SDM Strong Genetic Variation [113]
PRDM16 OT0BGA27 Strong Biomarker [1296]
PREX1 OTUTPVA9 Strong Biomarker [1297]
PRIM2 OTGT0KTF Strong Genetic Variation [1176]
PRKAA2 OTU1KZPV Strong Biomarker [915]
PRKAB1 OT1OG4QZ Strong Biomarker [915]
PRKAB2 OTLVN68B Strong Biomarker [1298]
PRKAG2 OTHTAM54 Strong Genetic Variation [1299]
PRKN OTJBN41W Strong Biomarker [1300]
PROK2 OT70IFEZ Strong Biomarker [1301]
PROS1 OTXQWNOI Strong Altered Expression [565]
PRRT2 OTCJUBDO Strong Biomarker [539]
PRRX1 OTTZK5G8 Strong Genetic Variation [409]
PRSS55 OTXXWI5Y Strong Altered Expression [1119]
PSD3 OTTN9B9O Strong Genetic Variation [1302]
PSMD9 OT6Y5CC3 Strong Biomarker [1303]
PTGFRN OTBG4SA2 Strong Genetic Variation [366]
PTPA OTRGFOI7 Strong Biomarker [1304]
PTPN23 OT5WDPXB Strong Genetic Variation [528]
PTPN4 OT6SXU5Y Strong Biomarker [1305]
PTPN5 OT2H1KDK Strong Biomarker [1306]
PTPN9 OTNAR1I2 Strong Biomarker [181]
PTPRF OTH5KF2D Strong Biomarker [181]
PTPRN OTAP7NOL Strong Biomarker [1307]
PTPRU OTHDO0QG Strong Genetic Variation [704]
PURG OTXPQDWN Strong Genetic Variation [366]
PVALB OTZW1WVQ Strong Biomarker [1308]
PYCARD OT67RON3 Strong Altered Expression [594]
QRSL1 OTJDU2UG Strong Genetic Variation [1309]
RAB14 OTF1J0TB Strong Biomarker [413]
RAB18 OTNMAQLS Strong Altered Expression [1310]
RAB3GAP1 OT4DQ8F2 Strong Genetic Variation [1311]
RAB4A OT7BL9WW Strong Altered Expression [1310]
RAB5B OT06PN42 Strong Biomarker [1310]
RAG1 OTV131E4 Strong Biomarker [1312]
RAI1 OTKLQU00 Strong Genetic Variation [366]
RALY OT78NNWY Strong Genetic Variation [366]
RAMP2 OTGQXLH5 Strong Genetic Variation [113]
RAPGEF5 OT53VS75 Strong Biomarker [1313]
RBM14 OTO9GMBD Strong Biomarker [1314]
RBM19 OT3Q6UIM Strong Genetic Variation [409]
RBM6 OTI99KAZ Strong Biomarker [1194]
RBPJL OTQD8S4N Strong Genetic Variation [551]
REG1B OTSC2133 Strong Biomarker [1314]
RELN OTLKMW1O Strong Genetic Variation [366]
RFC1 OT3L5PK3 Strong Biomarker [1315]
RFLNA OT6GS3XQ Strong Genetic Variation [366]
RFX6 OT8H77DL Strong Genetic Variation [1316]
RFX7 OTKFNW3A Strong Biomarker [461]
RGS13 OTPAMQ18 Strong Genetic Variation [310]
RGS7 OTDQA90X Strong Genetic Variation [1201]
RHOBTB1 OTGE8K45 Strong Genetic Variation [409]
RMC1 OT7K8MTJ Strong Altered Expression [1317]
RND3 OTXMXPIH Strong Biomarker [1318]
RNLS OTVP2WJM Strong Biomarker [804]
RNPC3 OTW5MKC1 Strong Biomarker [1319]
RPGRIP1L OT6Z069I Strong Genetic Variation [409]
RRAS OTBBF28C Strong Altered Expression [1320]
RREB1 OT62460U Strong Genetic Variation [113]
RTN4RL1 OTDKKOE7 Strong Genetic Variation [1321]
SACM1L OT6ORKTD Strong Biomarker [1322]
SAMM50 OTRYFYIU Strong Genetic Variation [366]
SARDH OTQ49Q27 Strong Biomarker [665]
SBNO1 OTNX3RL0 Strong Genetic Variation [528]
SCD5 OTSSUQ3Z Strong Genetic Variation [366]
SCGN OTGD7SKH Strong Altered Expression [1323]
SCN1B OTGD78J3 Strong Biomarker [1324]
SDF2L1 OTE7JIO2 Strong SusceptibilityMutation [1325]
SDHAF4 OTDXI4H8 Strong Genetic Variation [1276]
SELENBP1 OT3NZNTR Strong Biomarker [1095]
SELENOS OTUEWIU9 Strong Genetic Variation [1326]
SEMA6A OTDQ7QAW Strong Biomarker [1327]
SENP2 OTPQJXIR Strong Genetic Variation [528]
SEPTIN1 OT4GVSU3 Strong Biomarker [1328]
SERPINA3 OT9BP2S0 Strong Biomarker [1329]
SERPINE2 OTYF5340 Strong Biomarker [1330]
SERPINF2 OTZGAF8B Strong Biomarker [1331]
SESN2 OT889IXY Strong Altered Expression [1332]
SETDB2 OTBVVP9Q Strong Biomarker [1333]
SFI1 OTI1P52G Strong Genetic Variation [258]
SFN OTLJCZ1U Strong Altered Expression [282]
SFXN1 OTL66767 Strong Genetic Variation [1334]
SGCD OTRBL3NQ Strong Biomarker [1318]
SGSM3 OTIB1P8A Strong Biomarker [544]
SINHCAF OTHMZZ0A Strong Genetic Variation [113]
SIRT4 OT5S0J23 Strong Biomarker [1335]
SKA1 OTDYJ12A Strong Altered Expression [1336]
SLAMF1 OTBTT3ZQ Strong Altered Expression [479]
SLC35G1 OTKZUA8O Strong Biomarker [1134]
SMAD4 OTWQWCKG Strong Biomarker [1337]
SMARCAD1 OT90AZTX Strong Genetic Variation [918]
SNAP23 OTY2MYBX Strong Altered Expression [1338]
SND1 OTT734JN Strong Genetic Variation [113]
SNRNP70 OTP52YZ3 Strong Genetic Variation [1339]
SNX7 OTO8J1D0 Strong Genetic Variation [409]
SOAT1 OTB4Y5RJ Strong Biomarker [1340]
SOCS2 OTBPNKJQ Strong Altered Expression [1341]
SORBS1 OTWH8762 Strong Biomarker [475]
SORCS1 OTP8PAKU Strong Biomarker [1342]
SOX4 OTSS40SS Strong Genetic Variation [1343]
SP6 OTRAB1PN Strong Biomarker [1344]
SPHKAP OT5RHUYJ Strong Genetic Variation [366]
SPIC OTUOMSRP Strong Biomarker [1345]
SPINK1 OTSUVAL2 Strong Genetic Variation [1346]
SPINK4 OTHTCW94 Strong Biomarker [1347]
SPPL3 OT2HLJF6 Strong Genetic Variation [113]
SPRR2A OT62ZU6B Strong Altered Expression [216]
SPRY2 OTH0CRCZ Strong Biomarker [1348]
SPZ1 OTQH8HJ5 Strong Altered Expression [1119]
SRBD1 OTL1QJSP Strong Genetic Variation [1286]
SRI OT4R3EAC Strong Biomarker [1349]
SRL OT7IEBWZ Strong Biomarker [665]
SRSF5 OTC5WP98 Strong Biomarker [1189]
SSR1 OTQ6GDL2 Strong Genetic Variation [1350]
ST3GAL3 OTOORKUE Strong Genetic Variation [418]
ST3GAL4 OTNENJZQ Strong Biomarker [1351]
ST6GALNAC3 OTLAQ14Q Strong Genetic Variation [409]
STARD9 OTZ5CIXU Strong Genetic Variation [418]
STAT5A OTBSJGN3 Strong Biomarker [479]
STUB1 OTSUYI9A Strong Biomarker [1352]
STX4 OTQ7YUX1 Strong Biomarker [1353]
SUCLA2 OTMZD4PW Strong Biomarker [1354]
TADA2A OTXUMEL9 Strong Genetic Variation [304]
TAFA5 OT2SWBT6 Strong Biomarker [1355]
TAPBP OTL81AVZ Strong Biomarker [1356]
TBC1D1 OTI9V7B0 Strong Genetic Variation [1357]
TBC1D4 OTK66C40 Strong Genetic Variation [1357]
TCF7 OT1ID822 Strong Biomarker [1358]
TERF2IP OT3M5P3G Strong Genetic Variation [1359]
TEX14 OTBL9LPZ Strong Genetic Variation [366]
TFAM OTXXV5V7 Strong Biomarker [1360]
TFAP2B OTR1T8E9 Strong Genetic Variation [178]
TFB1M OTFCUSAZ Strong Genetic Variation [1361]
TFEB OTJUJJQY Strong Biomarker [1289]
TGFBI OTR443C5 Strong Biomarker [1362]
TGFBR3 OTQOOUC4 Strong Genetic Variation [409]
TGFBRAP1 OT80QNR5 Strong Genetic Variation [599]
THSD4 OTXDBMDC Strong Genetic Variation [1065]
TIMM44 OTXP7MXN Strong Biomarker [1188]
TLE1 OT50MRZ1 Strong Genetic Variation [1061]
TLR10 OTQ1KVJO Strong Altered Expression [1363]
TMBIM4 OT8712PP Strong Genetic Variation [1364]
TMEM132A OTNUI7O1 Strong Genetic Variation [1365]
TMEM154 OTEAFLJE Strong Genetic Variation [1366]
TMEM163 OTCT1Y1L Strong Biomarker [1367]
TNFAIP6 OT1SLUZH Strong Genetic Variation [310]
TNMD OTHLVA9G Strong Genetic Variation [1368]
TP53INP1 OT2363Z9 Strong Genetic Variation [178]
TPM1 OTD73X6R Strong Altered Expression [1369]
TPM4 OTN4YLYR Strong Genetic Variation [1087]
TPRG1L OTU7GPKK Strong Altered Expression [1370]
TRDN OTXVE9SF Strong Genetic Variation [1371]
TRIB3 OTG5OS7X Strong Biomarker [1372]
TRIM47 OTM9DGUD Strong Genetic Variation [1373]
TRIM72 OTFAFXPC Strong Biomarker [1374]
TRIOBP OTGB5WHC Strong Genetic Variation [409]
TRMT10A OTQ5AKN4 Strong Genetic Variation [1375]
TSC22D1 OTN4GFWD Strong Biomarker [1376]
TSEN2 OT1UWYRI Strong Altered Expression [1127]
TSHZ3 OTAN7RY5 Strong Genetic Variation [918]
TSPAN3 OT7WS6ZI Strong Genetic Variation [113]
TSPAN31 OT8WQ83R Strong Genetic Variation [1245]
TSPAN8 OT1F68WQ Strong Altered Expression [961]
TTC28 OTFOOYC3 Strong Altered Expression [1377]
TTC39C OTKKI81C Strong Genetic Variation [310]
TTLL6 OTHBM3DX Strong Genetic Variation [1127]
ACP1 OTJ9CKLU Definitive Biomarker [1378]
ADGRG1 OTQBB8NT Definitive Biomarker [1379]
ALPK1 OTBW6SGD Definitive Biomarker [1380]
AMPD1 OTU17BCI Definitive Biomarker [1381]
API5 OTYX9YCZ Definitive Genetic Variation [1382]
AQP5 OT77GBY8 Definitive Biomarker [1383]
AQR OTMNDXM1 Definitive Biomarker [1384]
ARHGEF11 OTDOMEH6 Definitive Genetic Variation [1385]
ARID2 OTIRJXWM Definitive Biomarker [1386]
ATP2A3 OTFYDEES Definitive Biomarker [1091]
ATP5MC1 OTOLSYOI Definitive Genetic Variation [366]
ATXN1 OTQF0HNR Definitive Biomarker [1387]
AZU1 OTHXU264 Definitive Biomarker [1388]
BACH2 OT17GS18 Definitive Biomarker [647]
BAZ1B OTD5KR2J Definitive Genetic Variation [1389]
CADM2 OT45PVKC Definitive Genetic Variation [1390]
CAMK2G OTHD9KJG Definitive Genetic Variation [366]
CAP1 OTYM8A2N Definitive Biomarker [475]
CBLIF OTNE20WU Definitive Altered Expression [1198]
CHGA OTXYX5JH Definitive Biomarker [1391]
COG2 OTKQH4N4 Definitive Biomarker [1392]
COL17A1 OTID5AH2 Definitive Biomarker [1393]
COL4A2 OTJK1LKN Definitive Genetic Variation [1394]
COLEC12 OTIQTK9G Definitive Genetic Variation [1382]
COMP OTS2FPMI Definitive Altered Expression [1395]
CPA6 OT43RD23 Definitive Biomarker [1396]
CRABP2 OTY01V9G Definitive Genetic Variation [1397]
CSAD OT3I2G0A Definitive Biomarker [1362]
DCLRE1C OTW3KB1I Definitive Genetic Variation [1398]
DLC1 OTP8LMCR Definitive Altered Expression [1399]
ECSCR OT9L72MD Definitive Biomarker [1400]
EFNB3 OT12WTXQ Definitive Genetic Variation [1401]
EGR2 OTAVQ78J Definitive Biomarker [1402]
EGR3 OTGPJIRA Definitive Biomarker [1403]
EIF2B5 OTV3R4RB Definitive Genetic Variation [641]
EIF4G1 OT2CF1E6 Definitive Genetic Variation [641]
ELOVL5 OT375W1Z Definitive Biomarker [1404]
ETFA OTXX61VZ Definitive Biomarker [1405]
FAM3A OTK1X62Z Definitive Biomarker [1406]
FAM3B OTC2S91N Definitive Biomarker [1406]
FANCD2 OTVEB5LF Definitive Biomarker [1407]
FGB OT6RKLI9 Definitive Genetic Variation [1408]
FGFBP3 OTWM1KCM Definitive Biomarker [1409]
FLOT1 OT0JPPJZ Definitive Altered Expression [561]
FUT2 OTLXM6WI Definitive Biomarker [1410]
GATAD2A OTFM8D3O Definitive Genetic Variation [73]
GDF1 OTZ1VRBH Definitive Biomarker [1411]
GFPT1 OTQBDO45 Definitive Altered Expression [751]
GLYR1 OTY0VAVL Definitive Biomarker [1412]
GMCL1 OTRZHUFV Definitive Biomarker [750]
GNPNAT1 OTOYH4L9 Definitive Biomarker [1413]
GOLGB1 OT2S0GK8 Definitive Biomarker [1414]
GORAB OTP65YD7 Definitive Biomarker [1382]
GPIHBP1 OTDF8R2M Definitive Altered Expression [1415]
GPR158 OTYOC1RQ Definitive Genetic Variation [1299]
HACD1 OTEC7EP7 Definitive Biomarker [475]
HACD3 OTISMCAF Definitive Biomarker [1416]
HADHA OTO557N2 Definitive Genetic Variation [1365]
HDLBP OTKDEEYX Definitive Biomarker [1388]
HEBP1 OTR9MPDX Definitive Biomarker [1388]
HEPH OTZ2F15Z Definitive Biomarker [1417]
HIRA OTON40EJ Definitive Altered Expression [654]
HLA-DOA OTZE5Q7R Definitive Biomarker [1418]
HLF OTTRK9XN Definitive Biomarker [1419]
HNRNPF OTSMBXMF Definitive Biomarker [1420]
HSD17B6 OTSB55D2 Definitive Altered Expression [680]
IGSF21 OTUFCXBS Definitive Genetic Variation [1099]
IL17B OTS86H50 Definitive Biomarker [450]
INHBE OTOI2NYG Definitive Altered Expression [1421]
IPO11 OTG19WN0 Definitive Altered Expression [409]
ITM2B OTMXEPXB Definitive Biomarker [1422]
KAT8 OT5LPQTR Definitive Biomarker [1423]
KCNE2 OTUO214Y Definitive Altered Expression [1424]
KLF15 OTGMQMVR Definitive Biomarker [1425]
KLHDC7A OTZAAF38 Definitive Genetic Variation [1099]
LARGE1 OTUH7H9F Definitive Genetic Variation [1426]
LEKR1 OTERQO47 Definitive Genetic Variation [1099]
LIG4 OT40DNXU Definitive Genetic Variation [895]
LYPLA1 OTENU47T Definitive Biomarker [1427]
LYPLAL1 OT8F2DCV Definitive Genetic Variation [308]
MASP1 OTWWCNZP Definitive Genetic Variation [1051]
MB OTYWYL2D Definitive Biomarker [1428]
MOCOS OT0TL3Q5 Definitive Genetic Variation [1429]
MPHOSPH9 OTNUNDQN Definitive Genetic Variation [1366]
MUC5B OTPW6K5C Definitive Biomarker [1430]
MXD1 OTS5CTHX Definitive Biomarker [1381]
MYF5 OTTVO2S5 Definitive Altered Expression [1431]
MYH6 OT3YNCH1 Definitive Altered Expression [1432]
NFKBIZ OTU728KS Definitive Genetic Variation [1433]
NLGN3 OTKDEC1Q Definitive Biomarker [397]
NPC2 OTE9UEJC Definitive Biomarker [1434]
NUTF2 OT8VA2ZF Definitive Altered Expression [1435]
OAS1 OT8ZLOCY Definitive Genetic Variation [893]
OAS3 OT6E5FYS Definitive Genetic Variation [1436]
OPN1MW OTPJ7LX4 Definitive Biomarker [1414]
OPN4 OT1LZ7TS Definitive Biomarker [1437]
OSBPL8 OTD50E5Y Definitive Posttranslational Modification [1438]
PAPPA OTTTG9PG Definitive Altered Expression [1439]
PAPSS2 OTDLEXPN Definitive Altered Expression [655]
PCOLCE2 OTSUEQZ1 Definitive Biomarker [1440]
PDHX OTG7O271 Definitive Genetic Variation [1441]
PDIK1L OTISF4KG Definitive Biomarker [358]
PDILT OT5D60QU Definitive Genetic Variation [1299]
PEX16 OTJQJ2TZ Definitive Genetic Variation [1442]
PIAS1 OTZVAHZI Definitive Genetic Variation [1365]
PICALM OTQVRPMQ Definitive Genetic Variation [1443]
PLIN5 OTV8G50L Definitive Altered Expression [1444]
POMGNT1 OTBNOUZC Definitive Genetic Variation [1445]
PPM1K OTNZ4N4E Definitive Genetic Variation [1446]
PPP1R13L OTNCPLWE Definitive Biomarker [1411]
PPP1R1B OTSIJMQ9 Definitive Biomarker [1447]
PREB OTT0KEZR Definitive Altered Expression [1448]
PSMA7 OTPHI6ST Definitive Biomarker [1449]
PSMD2 OT6HZHN7 Definitive Biomarker [641]
PTPRN2 OTL6SH28 Definitive Genetic Variation [418]
PTX3 OTPXHRKU Definitive Biomarker [1450]
PYGB OT2ZTJT0 Definitive Genetic Variation [1451]
RAB11A OTC4FW0J Definitive Biomarker [1452]
RCAN1 OT1MVXC7 Definitive Altered Expression [1453]
RCN2 OTIU8JWD Definitive Altered Expression [1454]
RHOD OTALMEIN Definitive Biomarker [1103]
RNH1 OT6EC79B Definitive Biomarker [1411]
ROM1 OTE7H0YV Definitive Altered Expression [1455]
ROMO1 OTIEYVBW Definitive Genetic Variation [1456]
SERPINA5 OTTZXPGD Definitive Biomarker [1457]
SERPINB6 OT7G55IK Definitive Biomarker [475]
SF1 OTLEDM2S Definitive Genetic Variation [1458]
SGMS1 OTZQE7PW Definitive Biomarker [1459]
SH2B1 OTJZO2CI Definitive Biomarker [1460]
SH2D1A OTLU49I5 Definitive Biomarker [630]
SHC1 OT1J5IRN Definitive Biomarker [647]
SHC3 OT305NPA Definitive Biomarker [1411]
SIGLEC1 OTNWSQA9 Definitive Altered Expression [351]
SIGLEC7 OTNDLURR Definitive Altered Expression [1461]
SIX3 OTP5E3VU Definitive Biomarker [1462]
SLBP OTVYYQRT Definitive Biomarker [1388]
SLMAP OTHW3DVC Definitive Genetic Variation [1463]
SMCP OTXKY794 Definitive Genetic Variation [1429]
SPON1 OTC06MY4 Definitive Altered Expression [1464]
SPTBN4 OTAJAVP9 Definitive Biomarker [1465]
SPTLC1 OTN0Z98K Definitive Biomarker [1466]
STAM2 OT9OBWPH Definitive Biomarker [1388]
STX8 OTFOJCHI Definitive Genetic Variation [409]
SUGP1 OT7W0EB8 Definitive Genetic Variation [366]
TAF1C OTNV4CDH Definitive Altered Expression [1467]
TCHHL1 OTAMOJGN Definitive Biomarker [1468]
TIMM8A OTDX9687 Definitive Biomarker [1469]
TPPP2 OTI3WA6X Definitive Genetic Variation [1470]
TSBP1 OT5GE8IO Definitive Genetic Variation [1471]
------------------------------------------------------------------------------------
⏷ Show the Full List of 1180 DOT(s)
This Disease Is Related to 741 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ACTG1 TTGAZF9 Limited Genetic Variation [55]
ADAM17 TT6AZXG Limited Biomarker [56]
ADRA2A TTWG9A4 Limited Genetic Variation [57]
AGPAT1 TTPL1TK Limited Biomarker [58]
AHR TT037IE Limited Genetic Variation [59]
AIF1 TT12MEP Limited Biomarker [60]
AKT1 TTWTSCV Limited Altered Expression [61]
AKT2 TTH24WI Limited Autosomal dominant [62]
AKT3 TTO6SGY Limited Genetic Variation [63]
ALCAM TT2AFT6 Limited Biomarker [64]
ANXA1 TTUCK4B Limited Biomarker [65]
ARG1 TT7ZQEV Limited Altered Expression [66]
AVP TTJ8EWH Limited Biomarker [67]
BACE1 TTJUNZF Limited Genetic Variation [68]
BCAT1 TTES57P Limited Genetic Variation [69]
BCL2L1 TTRE6AX Limited Biomarker [70]
BGN TT0JPVF Limited Biomarker [71]
BPI TTXCSDR Limited Biomarker [72]
BRAF TT0EOB8 Limited Genetic Variation [73]
BRD2 TTDP48B Limited Biomarker [74]
C5 TTKANGO Limited Genetic Variation [75]
CA2 TTANPDJ Limited Genetic Variation [76]
CACNA1C TTZIFHC Limited Altered Expression [77]
CACNA1E TTYRP0M Limited Biomarker [78]
CBR1 TTVG0SN Limited Biomarker [79]
CBS TTVZJ7G Limited Altered Expression [80]
CCN2 TTIL516 Limited Biomarker [81]
CCND3 TT1JXNR Limited Biomarker [82]
CCR1 TTC24WT Limited Biomarker [83]
CCR2 TTFZYTO Limited Biomarker [84]
CCR5 TTJIH8Q Limited Genetic Variation [85]
CD4 TTN2JFW Limited Genetic Variation [86]
CDH2 TT1WS0T Limited Biomarker [87]
CEACAM3 TTPX7I5 Limited Altered Expression [88]
CFD TT8D13I Limited Biomarker [89]
CGA TTFC29G Limited Genetic Variation [90]
CGB3 TTUH273 Limited Genetic Variation [90]
CHRNB4 TTTVAFQ Limited Genetic Variation [91]
COASY TT4YO0Z Limited Genetic Variation [92]
COL6A3 TT5WCAH Limited Altered Expression [93]
COMT TTKWFB8 Limited Genetic Variation [94]
CPT1B TTDL0NY Limited Biomarker [95]
CREB1 TTH4AN3 Limited Biomarker [96]
CRY2 TTAO58M Limited Genetic Variation [97]
CRYZ TTP6UO8 Limited Genetic Variation [98]
CS TTZA6B3 Limited Altered Expression [99]
CTSH TT3G406 Limited Genetic Variation [100]
CYP1A2 TTS1DTU Limited Biomarker [101]
CYP2A6 TTAQ6ZW Limited Biomarker [102]
DBH TTYIP79 Limited Genetic Variation [103]
DEFB4A TTIVY12 Limited Altered Expression [104]
DRD3 TT4C8EA Limited Biomarker [105]
DYRK3 TTV4EX0 Limited Biomarker [106]
EBP TT4VQZX Limited Biomarker [107]
ECE1 TTQ9RYT Limited Biomarker [108]
ELAVL1 TTPC9D0 Limited Biomarker [109]
ENAH TTY36UA Limited Biomarker [110]
ESRRB TTKF0XS Limited Altered Expression [111]
ESRRG TT9ZRHB Limited Biomarker [112]
ETS1 TTTGPSD Limited Genetic Variation [113]
F5 TT1O264 Limited Genetic Variation [114]
FABP3 TT3TGLR Limited Genetic Variation [115]
FABP5 TTNT2S6 Limited Biomarker [116]
FAF1 TTSKL3G Limited Genetic Variation [113]
FAS TT7LTUJ Limited Biomarker [117]
FGF21 TTQ916P Limited Altered Expression [118]
FGL2 TTYBS89 Limited Biomarker [119]
FN3K TTP6W8J Limited Genetic Variation [120]
G6PC TTBQMJ8 Limited Biomarker [121]
GCH1 TTLSWP6 Limited Genetic Variation [122]
GEM TTAZF9M Limited Biomarker [123]
GJA4 TTQO1VY Limited Genetic Variation [124]
GJD2 TTOZAFI Limited Biomarker [125]
GLRX TTRJCNG Limited Biomarker [126]
GNAO1 TTAXD8Z Limited Biomarker [127]
GP6 TTTJUVZ Limited Biomarker [128]
GPD1 TTKTEAH Limited Genetic Variation [129]
GPR132 TTNBW4F Limited Biomarker [130]
GPR35 TT254XD Limited Biomarker [131]
GRN TT0LWE3 Limited Biomarker [132]
GSK3B TTRSMW9 Limited Posttranslational Modification [133]
GSTA1 TT4P8DE Limited Genetic Variation [134]
HCAR2 TTWNV8U Limited Altered Expression [135]
HCN2 TT9EUT4 Limited Biomarker [136]
HDAC3 TT4YWTO Limited Biomarker [137]
HDAC9 TT8M4E1 Limited Biomarker [138]
HIF1A TTSN6QU Limited Altered Expression [139]
HLA-DQB2 TTL7VOU Limited Biomarker [127]
HMBS TTT0HW3 Limited Biomarker [140]
HMGA1 TTBA219 Limited Autosomal dominant [141]
HRC TTR4FKD Limited Biomarker [142]
HSD11B2 TT9H85R Limited Genetic Variation [143]
ID1 TTBXVDE Limited Biomarker [144]
IDE TT2EDHU Limited Biomarker [145]
IFNL3 TTRF4Q2 Limited Genetic Variation [146]
IGF2 TTE8WGO Limited Biomarker [147]
IGFBP5 TTDWEA8 Limited Genetic Variation [148]
IL12A TTRTK6Y Limited Biomarker [119]
IL13RA1 TTNEAMG Limited Genetic Variation [113]
IL4R TTDWHC3 Limited Genetic Variation [149]
KCNB1 TT5OEKU Limited Genetic Variation [150]
KCND3 TTPLQO0 Limited Genetic Variation [151]
KCNJ9 TT4VHL6 Limited Genetic Variation [152]
KCNU1 TTI9XK6 Limited Biomarker [73]
KEAP1 TT3Z6Y9 Limited Altered Expression [153]
KLK5 TTULSEW Limited Biomarker [154]
L3MBTL3 TTQDMJN Limited Genetic Variation [155]
LAMB3 TT2WOUQ Limited Genetic Variation [156]
LGR5 TTTSGRH Limited Genetic Variation [157]
LIN28A TTO50LN Limited Genetic Variation [158]
LPAR1 TTQ6S1K Limited Biomarker [159]
LTF TTSZDQU Limited Altered Expression [160]
LY75 TTG180Q Limited Genetic Variation [161]
LY96 TT8S9AV Limited Genetic Variation [162]
LYZ TTAOZBW Limited Genetic Variation [163]
MAN2A1 TT34DCN Limited Biomarker [164]
MANF TT56RYE Limited Altered Expression [165]
MAPK1 TT4TQBX Limited Biomarker [166]
MAPK8 TT0K6EO Limited Altered Expression [167]
MBOAT4 TTSYOWR Limited Altered Expression [168]
MC5R TT6QAJ3 Limited Genetic Variation [169]
MGAT2 TTJOW1I Limited Biomarker [170]
MLYCD TT9Z4YD Limited Biomarker [95]
MOGAT2 TTN17BP Limited Biomarker [171]
MSI2 TTTXQF6 Limited Genetic Variation [172]
MTOR TTCJG29 Limited Biomarker [173]
MYLK TT18ETS Limited Biomarker [174]
NCF1 TTZ4JC3 Limited Altered Expression [175]
NCR1 TTQNRJM Limited Biomarker [176]
NOD1 TTYSRXM Limited Biomarker [177]
NOTCH2 TT82FVD Limited Genetic Variation [178]
NPR1 TTM9IYA Limited Altered Expression [179]
NPR2 TTNB7IF Limited Altered Expression [179]
NPR3 TTWVLS6 Limited Genetic Variation [180]
NR0B2 TT25A9Q Limited Biomarker [181]
NR4A2 TT9HKN3 Limited Altered Expression [182]
OSM TTIVXSE Limited Biomarker [183]
P2RY12 TTZ1DT0 Limited Altered Expression [184]
PDE4D TTSKMI8 Limited Biomarker [185]
PEMT TT735V2 Limited Genetic Variation [186]
PEPD TTLZXI0 Limited Genetic Variation [113]
PFKFB2 TTQYVKD Limited Genetic Variation [187]
PNLIP TTXMY0J Limited Genetic Variation [188]
PROM1 TTXMZ81 Limited Biomarker [189]
PTGES2 TTWU04I Limited Genetic Variation [190]
PTPRB TT64I9Q Limited Altered Expression [191]
PTPRS TTCWXFA Limited Biomarker [192]
RBP4 TT0C8BY Limited Biomarker [193]
REL TT1ZCTH Limited Genetic Variation [194]
RIPK2 TTCQ2E5 Limited Biomarker [195]
RNF6 TT4S09X Limited Genetic Variation [113]
ROBO4 TT3S9TY Limited Altered Expression [196]
S100A6 TT716MY Limited Biomarker [144]
S100A9 TT0TMQG Limited Biomarker [197]
SAA1 TTY0DN9 Limited Biomarker [198]
SETD7 TTJ0FSU Limited Biomarker [199]
SFTPD TTGLMU7 Limited Biomarker [200]
SIRT5 TTH0IOD Limited Biomarker [201]
SLC12A3 TTP362L Limited Genetic Variation [202]
SLC17A5 TTFSUIA Limited Altered Expression [203]
SLC18A2 TTNZRI3 Limited Biomarker [204]
SLC1A2 TT2F078 Limited Genetic Variation [113]
SLC1A5 TTF7WRM Limited Genetic Variation [205]
SLC1A7 TTK41DM Limited Genetic Variation [205]
SLC22A12 TTA592U Limited Biomarker [206]
SLC22A16 TTITAVR Limited Biomarker [207]
SLC2A9 TTIF3GB Limited Biomarker [208]
SLC38A2 TTUSC27 Limited Altered Expression [209]
SLC6A8 TTYUHB5 Limited Biomarker [210]
SLC8A1 TTCF82X Limited Altered Expression [211]
SLCO1A2 TTUGD21 Limited Biomarker [212]
SLCO1B3 TTU86P0 Limited Genetic Variation [213]
SMAD1 TT9GR53 Limited Biomarker [214]
SOX5 TTXHSZK Limited Biomarker [215]
SQSTM1 TTOT2RY Limited Altered Expression [216]
SRC TT6PKBN Limited Biomarker [217]
SRD5A2 TTT02K8 Limited Altered Expression [218]
SSTR2 TTZ6T9E Limited Biomarker [219]
SUCNR1 TT4FX9Y Limited Biomarker [220]
TACR3 TTBPGLU Limited Genetic Variation [63]
TCIRG1 TTVRN05 Limited Biomarker [221]
TEK TT9VGXW Limited Biomarker [222]
TEP1 TTQGAVX Limited Genetic Variation [223]
TERF2 TT5XSLT Limited Genetic Variation [223]
TFPI TT068JH Limited Biomarker [224]
TH TTUHP71 Limited Genetic Variation [225]
TIAM1 TTNU6I5 Limited Biomarker [226]
TLR5 TTCXP8J Limited Genetic Variation [227]
TNFRSF25 TTDV6BQ Limited Biomarker [228]
TNFSF14 TTKVENM Limited Biomarker [229]
TREM2 TTQRMSJ Limited Genetic Variation [230]
TRPM2 TTEBMN7 Limited Biomarker [231]
TRPM4 TTJ2HKA Limited Biomarker [232]
UGCG TTPHEX3 Limited Biomarker [233]
USP2 TTUEQ1W Limited Biomarker [234]
UTS2R TTW5UDX Limited Biomarker [235]
VEGFB TTPJQHE Limited Altered Expression [236]
VKORC1 TTEUC8H Limited Genetic Variation [237]
ALPL TTMR5UV Disputed Altered Expression [238]
AMD1 TTBFROQ Disputed Genetic Variation [239]
BIRC2 TTQ5LRD Disputed Biomarker [240]
BRD9 TTR7L5Y Disputed Biomarker [241]
DGKZ TTSBBXL Disputed Biomarker [242]
GDF2 TTAP4T1 Disputed Biomarker [243]
HTR2B TT0K1SC Disputed Biomarker [244]
NAGLU TTDM6HZ Disputed Biomarker [245]
NLRX1 TTKT026 Disputed Genetic Variation [246]
PLTP TTZF6SN Disputed Altered Expression [247]
RPS6KA2 TT0ZW9O Disputed Biomarker [248]
S100A12 TTQ4ESF Disputed Biomarker [249]
SIGMAR1 TT5TPI6 Disputed Biomarker [250]
SLC39A6 TTZN1CF Disputed Biomarker [251]
TFRC TT8MG4S Disputed Altered Expression [252]
AIMP2 TTXWHGF moderate Biomarker [166]
ALAS1 TTG1FXO moderate Genetic Variation [253]
ANK1 TTKFPMH moderate Genetic Variation [113]
APLN TT87D3J moderate Biomarker [254]
AQP7 TTNGCRK moderate Biomarker [255]
BCHE TT3MSAO moderate Biomarker [256]
CALCA TTVSFJW moderate Biomarker [257]
CDC123 TT3PRUG moderate Genetic Variation [258]
CLCN3 TT8XNZ7 moderate Biomarker [259]
CRK TTFEUYR moderate Biomarker [166]
CYP3A4 TTWP7HQ moderate Biomarker [260]
DMD TTWLFXU moderate Altered Expression [261]
EPHX2 TT7WVHI moderate Genetic Variation [262]
F2R TTL935N moderate Altered Expression [263]
GAP43 TTSGLN5 moderate Biomarker [264]
GLUL TTURQ2G moderate Genetic Variation [265]
GPRC6A TTI1PRE moderate Biomarker [266]
HMGB1 TTWQYB7 moderate Biomarker [267]
HMGCR TTPADOQ moderate Genetic Variation [268]
IGFBP3 TTZHNQA moderate Biomarker [269]
IL22 TTLDX4N moderate Biomarker [270]
IL5 TTPREZD moderate Biomarker [271]
ITGA1 TTPERWV moderate Genetic Variation [113]
KCNJ10 TTG140O moderate Genetic Variation [152]
LDLR TTH0DUS moderate Biomarker [272]
MAPK3 TT1MG9E moderate Biomarker [273]
MAPK7 TTU6FSC moderate Altered Expression [274]
MME TT5TKPM moderate Biomarker [275]
MMP3 TTUZ2L5 moderate Biomarker [276]
MPO TTVCZPI moderate Altered Expression [277]
PAM TTF4ZPC moderate Genetic Variation [178]
PLA2G2A TTO8QRU moderate Genetic Variation [278]
PPIA TTL2ADK moderate Altered Expression [279]
REG3A TTL4H8N moderate Biomarker [280]
RENBP TTZCG0Q moderate Biomarker [281]
ROCK1 TTZN7RP moderate Altered Expression [282]
SDC2 TT5H2F0 moderate Genetic Variation [283]
SELPLG TTS5K8U moderate Biomarker [284]
SLC22A3 TTG2UMS moderate Altered Expression [285]
SLC52A2 TT6TKEN moderate Altered Expression [263]
SLCO1B1 TTFGXEB moderate Genetic Variation [286]
SST TTWF7UG moderate Biomarker [287]
TERF1 TT1Y6J2 moderate Biomarker [288]
TGFB1 TTR9XHZ moderate Genetic Variation [289]
TRH TT2Z39D moderate Biomarker [288]
TXNIP TTTLDZK moderate Altered Expression [290]
VEGFC TT0QUFV moderate Biomarker [291]
ABCC2 TTFLHJV Strong Biomarker [292]
ABCG2 TTIMJ02 Strong Altered Expression [293]
ABCG5 TTKZ7WY Strong Biomarker [294]
ABHD6 TTSINOV Strong Biomarker [295]
ACACB TTY84UG Strong Genetic Variation [296]
ACAT1 TTK3C21 Strong Altered Expression [297]
ACE2 TTUI5H7 Strong Biomarker [56]
ACHE TT1RS9F Strong Altered Expression [298]
ACKR3 TTRQJTC Strong Biomarker [299]
ACLY TT0Z6Y2 Strong Biomarker [300]
ADGRL3 TTQST3U Strong Biomarker [301]
ADM TTV14YH Strong Biomarker [302]
ADM2 TTM642F Strong Altered Expression [303]
ADORA1 TTK25J1 Strong Altered Expression [304]
ADORA2B TTNE7KG Strong Altered Expression [305]
ADORA3 TTJFY5U Strong Altered Expression [305]
ADRA1A TTNGILX Strong Biomarker [299]
ADRA2B TTWM4TY Strong Biomarker [299]
ADRB2 TTG8ZWP Strong Genetic Variation [306]
AGRP TT4DE1O Strong Biomarker [307]
AGTR2 TTQVOEI Strong Genetic Variation [308]
ALDH2 TTFLN4T Strong Biomarker [309]
ALK TTPMQSO Strong Genetic Variation [310]
ALOX12 TT12ABZ Strong Biomarker [311]
ALOX15 TTN9T81 Strong Biomarker [311]
ALOX5AP TTDMBF5 Strong Biomarker [312]
AMY2A TTCGSZ4 Strong Altered Expression [313]
ANGPT1 TTWNQ1T Strong Biomarker [314]
ANGPTL3 TT59GO7 Strong Genetic Variation [315]
ANPEP TTPHMWB Strong Altered Expression [316]
AOC3 TT7HC21 Strong Biomarker [317]
APLNR TTJ8E43 Strong Altered Expression [318]
APOA4 TTNC3WS Strong Altered Expression [319]
APOC3 TTXOZQ1 Strong Biomarker [320]
APOH TT2OUI9 Strong Biomarker [321]
APOL1 TTDB8PW Strong Biomarker [322]
APP TTE4KHA Strong Altered Expression [323]
AQP9 TTQEI32 Strong Biomarker [324]
AR TTKPW01 Strong Biomarker [325]
ARRB2 TT8SO2I Strong Biomarker [326]
ARSA TTYQANR Strong Genetic Variation [327]
ATF3 TTCE793 Strong Altered Expression [328]
ATG7 TTLVB9Z Strong Altered Expression [329]
ATIC TT9NVXQ Strong Altered Expression [330]
ATP2A2 TTE6THL Strong Biomarker [331]
ATXN2 TTPQJ7P Strong Genetic Variation [332]
AVPR2 TTK8R02 Strong Biomarker [333]
AZGP1 TTUPYLV Strong Biomarker [334]
B2M TTY7FKA Strong Biomarker [335]
BACE2 TT69DB8 Strong Biomarker [336]
BAX TTQ57WJ Strong Altered Expression [167]
BCL11A TTR61MW Strong Biomarker [337]
BCL2 TTFOUV4 Strong Altered Expression [338]
BDNF TTSMLOH Strong Altered Expression [339]
BECN1 TT5M7LN Strong Altered Expression [216]
BLK TTNDSC3 Strong Genetic Variation [340]
BMP7 TTKOBRA Strong Biomarker [341]
BRS3 TTKYEPM Strong Biomarker [299]
C3 TTJGY7A Strong Biomarker [342]
CA5A TT75WPO Strong Altered Expression [343]
CACNA1D TT7RGTM Strong Genetic Variation [77]
CAPN1 TT1WBIJ Strong Biomarker [344]
CAPN2 TTG5QB7 Strong Biomarker [344]
CASP1 TTCQIBE Strong Altered Expression [345]
CASP3 TTPF2QI Strong Altered Expression [338]
CASP7 TTM7Y45 Strong Biomarker [346]
CCKAR TTCG0AL Strong Biomarker [347]
CCKBR TTVFO0U Strong Genetic Variation [348]
CCL22 TTBTWI1 Strong Biomarker [349]
CD14 TT6I7DC Strong Altered Expression [350]
CD163 TTTZ9DE Strong Altered Expression [351]
CD33 TTJVYO3 Strong Biomarker [352]
CD38 TTPURFN Strong Biomarker [353]
CD59 TTBGTEJ Strong Biomarker [354]
CDK9 TT1LVF2 Strong Biomarker [355]
CDKN1C TTBSUAR Strong Genetic Variation [356]
CEACAM5 TTY6DTE Strong Altered Expression [357]
CEBPB TTUI35N Strong Biomarker [358]
CEL TTTRNQW Strong Genetic Variation [359]
CELA1 TT3NKIB Strong Biomarker [360]
CES1 TTMF541 Strong Biomarker [361]
CFB TTA0P7K Strong Biomarker [362]
CHIT1 TTDYX6T Strong Altered Expression [363]
CHM TTOA18V Strong Biomarker [364]
CHMP4B TT09EZF Strong Genetic Variation [178]
CHRM3 TTQ13Z5 Strong Biomarker [365]
CHUK TT1F8OQ Strong Genetic Variation [366]
CLCN2 TT30NW6 Strong Biomarker [367]
CNTF TTGEM5Q Strong Biomarker [368]
CNTLN TT8MI6U Strong Genetic Variation [369]
CPA1 TT3LJ6G Strong Genetic Variation [113]
CPB2 TTP18AY Strong Altered Expression [370]
CRHR1 TT7EFHR Strong Biomarker [371]
CRTC1 TT4GO0F Strong Biomarker [372]
CRTC2 TTFWETR Strong Biomarker [373]
CTF1 TTXGTZU Strong Biomarker [374]
CTSD TTPT2QI Strong Altered Expression [375]
CUBN TT9YLCR Strong Genetic Variation [376]
CXCR6 TT2BVUA Strong Biomarker [299]
CYP11A1 TTSYVO6 Strong Biomarker [377]
CYP11B2 TT9MNE2 Strong Genetic Variation [378]
CYP21A2 TTP4GLG Strong Genetic Variation [308]
CYP2B6 TTMH124 Strong Altered Expression [293]
CYP2C19 TTZ58XG Strong Biomarker [379]
CYP2C9 TTR40YJ Strong Genetic Variation [293]
CYP2E1 TTWVHQ5 Strong Genetic Variation [380]
CYP2J2 TTNE1C7 Strong Genetic Variation [293]
CYP3A5 TTHS0OK Strong Genetic Variation [381]
DAG1 TT4X7PG Strong Biomarker [382]
DAPK3 TTERVQN Strong Genetic Variation [383]
DLL1 TT9CFQD Strong Genetic Variation [384]
DNASE1 TTYWGOJ Strong Biomarker [385]
DNMT1 TT6S2FE Strong Posttranslational Modification [386]
DUSP9 TT1GV6C Strong Genetic Variation [113]
DYRK1A TTSBVFO Strong Altered Expression [80]
EBI3 TTJF68X Strong Biomarker [387]
EDN1 TTJR60Z Strong Biomarker [388]
EDNRA TTKRD0G Strong Biomarker [299]
EDNRB TT3ZTGU Strong Biomarker [389]
EIF2AK2 TTXEZJ4 Strong Biomarker [390]
EIF2AK3 TT79U1M Strong Biomarker [391]
EIF2AK4 TT9U4EP Strong Biomarker [392]
ELANE TTPLTSQ Strong Biomarker [270]
ENSA TTQD0YT Strong Biomarker [393]
ENTPD1 TTYM8DJ Strong Altered Expression [60]
ENTPD3 TT7ES5I Strong Biomarker [394]
EPAS1 TTWPA54 Strong Biomarker [395]
EPHA4 TTG84D3 Strong Genetic Variation [396]
EPOR TTAUX24 Strong Biomarker [397]
ESRRA TTPNQAC Strong Biomarker [398]
EYA2 TTUY9C6 Strong Genetic Variation [366]
F2RL2 TTVSEBF Strong Biomarker [399]
F7 TTF0EGX Strong Biomarker [400]
FABP4 TTHWMFZ Strong Biomarker [401]
FAT1 TTGUJYV Strong Genetic Variation [402]
FBXW7 TT29KY7 Strong Genetic Variation [113]
FCGR2B TT5RWKQ Strong Biomarker [403]
FCGR3A TTIFOC0 Strong Altered Expression [351]
FFAR1 TTB8FUC Strong Biomarker [404]
FFAR2 TT0FYAN Strong Biomarker [405]
FFAR3 TTXDOHN Strong Posttranslational Modification [406]
FFAR4 TT08JVB Strong Biomarker [407]
FGF1 TTMY81X Strong Biomarker [408]
FGF14 TTKJX1V Strong Genetic Variation [409]
FGF19 TTGCH11 Strong Altered Expression [410]
FGF23 TT2IZ4K Strong Biomarker [411]
FHL1 TTI7ENL Strong Genetic Variation [412]
FOLR1 TTVC37M Strong Biomarker [413]
FOLR2 TTT54CI Strong Biomarker [413]
FOSL1 TTY8LZG Strong Altered Expression [414]
FOXM1 TTD3KOX Strong Genetic Variation [415]
FOXP1 TT0MUCI Strong Genetic Variation [409]
FST TTDNM9W Strong Biomarker [416]
FSTL3 TTWRPM8 Strong Altered Expression [416]
G6PC2 TT7EV4P Strong Genetic Variation [417]
GABRG2 TT06RH5 Strong Biomarker [367]
GABRG3 TTEX6LM Strong Genetic Variation [418]
GAD1 TTKGEP3 Strong Biomarker [419]
GAD2 TT7UY6K Strong Biomarker [420]
GAL TTXZAJ5 Strong Biomarker [421]
GAST TT4LRVO Strong Biomarker [422]
GFAP TTI6FFX Strong Biomarker [423]
GHR TTHJWYD Strong Genetic Variation [424]
GJA1 TT4F7SL Strong Altered Expression [425]
GLA TTIS03D Strong Genetic Variation [426]
GPBAR1 TTSDVTR Strong Biomarker [427]
GPR119 TT7QNVC Strong Biomarker [428]
GPR39 TTTPCNU Strong Altered Expression [429]
GPR55 TTNET8J Strong Biomarker [430]
GPX1 TTYAHBP Strong Biomarker [431]
GRK5 TTTCXO0 Strong Genetic Variation [432]
GSN TTUH7OM Strong Biomarker [433]
GSR TTEP6RV Strong Biomarker [434]
HAMP TTRV5YJ Strong Biomarker [435]
HDAC7 TTMUEK1 Strong Biomarker [138]
HPGDS TTCYE56 Strong Biomarker [436]
HSP90B1 TTFPKXQ Strong Altered Expression [437]
HSPA9 TTMTPG3 Strong Altered Expression [438]
HSPB8 TTY0OJN Strong Biomarker [439]
HTR2A TTJQOD7 Strong Biomarker [440]
HTR2C TTWJBZ5 Strong Genetic Variation [441]
HTR3B TTR6K75 Strong Genetic Variation [440]
HTR4 TT07C3Y Strong Biomarker [440]
ICOS TTE5VP6 Strong Biomarker [442]
ICOSLG TTB9Z8R Strong Biomarker [442]
IGF2R TTPNE41 Strong Genetic Variation [443]
IGFBP1 TTCJTWF Strong Biomarker [444]
IGFBP2 TTU4QSN Strong Genetic Variation [445]
IKBKB TTJ3E9X Strong Biomarker [446]
IL12B TTGW72V Strong Genetic Variation [447]
IL17A TTG0MT6 Strong Biomarker [448]
IL1R1 TTWOTEA Strong Altered Expression [449]
IL20 TTNZMY2 Strong Biomarker [450]
IL23A TTC1GLB Strong Biomarker [451]
IL32 TTD4G7L Strong Altered Expression [452]
IL33 TT5MD4P Strong Biomarker [453]
IL37 TTQTX98 Strong Altered Expression [454]
IL4 TTLGTKB Strong Genetic Variation [455]
IRAK4 TTILUKB Strong Genetic Variation [456]
ITGA2 TTSJ542 Strong Genetic Variation [457]
ITGAM TTB69FJ Strong Altered Expression [351]
JAK1 TT6DM01 Strong Biomarker [458]
KCNC4 TTODZF1 Strong Biomarker [459]
KCNJ3 TTGM19J Strong Genetic Variation [460]
KCNK3 TTGR91N Strong Biomarker [461]
KCNMA1 TTE87WJ Strong Altered Expression [462]
KCNQ3 TTIVDM3 Strong Genetic Variation [225]
KHDRBS1 TTAT6C7 Strong Altered Expression [216]
KIF11 TTBGTCW Strong Genetic Variation [463]
KIF20B TTQECT2 Strong Biomarker [464]
KIR2DS1 TTVWAGF Strong Genetic Variation [465]
KIR3DL2 TTQH3N0 Strong Genetic Variation [465]
KLB TTARBVH Strong Altered Expression [466]
KLK3 TTS78AZ Strong Biomarker [467]
KLRK1 TTLRN4A Strong Altered Expression [468]
KNG1 TTDJ4MY Strong Biomarker [469]
LCN2 TTKTLAI Strong Biomarker [470]
LDHA TTW76JE Strong Biomarker [471]
LGALS3 TTFPQV7 Strong Biomarker [472]
LIF TTGZ5WN Strong Genetic Variation [473]
LILRB1 TTC0QRJ Strong Biomarker [474]
LNPEP TTY2KP7 Strong Biomarker [475]
LOXL2 TTFSUHX Strong Altered Expression [476]
LPAR2 TTB7Y8I Strong Biomarker [299]
LPAR3 TTE2YJR Strong Biomarker [266]
LRP1 TTF2V7I Strong Altered Expression [477]
LRP2 TTPH1AJ Strong Altered Expression [478]
LRP6 TTSXOWE Strong Altered Expression [414]
LY9 TTZCL1U Strong Biomarker [479]
MALT1 TTCI81G Strong Genetic Variation [480]
MAP2K7 TT6QY3J Strong Biomarker [173]
MAP3K8 TTGECUM Strong Altered Expression [481]
MAPK14 TTQBR95 Strong Biomarker [166]
MAPK8IP1 TTXKZ8Q Strong Posttranslational Modification [482]
MAPK9 TT3IVG2 Strong Biomarker [483]
MARK2 TTAJ45Y Strong Altered Expression [263]
MAS1 TTOISYB Strong Biomarker [367]
MBP TT2RY5P Strong Altered Expression [484]
MBTPS1 TTNSM2I Strong Altered Expression [485]
MCM6 TTQGKSD Strong Genetic Variation [409]
MGAM TTXWASR Strong Biomarker [486]
MGLL TTZ963I Strong Genetic Variation [369]
MIF TT6804T Strong Genetic Variation [487]
MKI67 TTB4UNG Strong Biomarker [488]
MMP1 TTMX39J Strong Genetic Variation [489]
MMP12 TTXZ0KQ Strong Biomarker [490]
MMP8 TTGA1IV Strong Biomarker [491]
MRGPRX1 TTIX6PK Strong Biomarker [266]
MSTN TTM8I2X Strong Biomarker [492]
MTNR1A TT0WAIE Strong Biomarker [493]
MTR TTUTO39 Strong Biomarker [494]
MTTP TTUS1RD Strong Genetic Variation [495]
MUTYH TTNB0ZK Strong Genetic Variation [496]
MYCBP TTVW4XU Strong Biomarker [497]
NAMPT TTD1WIG Strong Biomarker [498]
NFKB1 TTUIZKC Strong Biomarker [499]
NISCH TT789FN Strong Biomarker [500]
NOS1 TTZUFI5 Strong Altered Expression [501]
NOS2 TTF10I9 Strong Altered Expression [501]
NOX4 TTQRBSJ Strong Altered Expression [502]
NPC1L1 TTPD1CN Strong Genetic Variation [503]
NPEPPS TT371QC Strong Biomarker [467]
NPY TT64REZ Strong Genetic Variation [504]
NR1D1 TTAD1O8 Strong Biomarker [505]
NR1H2 TTXA6PH Strong Genetic Variation [506]
NR1H4 TTS4UGC Strong Altered Expression [507]
NR3C2 TT26PHO Strong Biomarker [508]
NR4A1 TTMXE2Q Strong Altered Expression [509]
NRG1 TTEH395 Strong Altered Expression [510]
NSD1 TTTSJ3H Strong Biomarker [461]
NTN1 TT0AH4L Strong Altered Expression [511]
NTRK2 TTKN7QR Strong Genetic Variation [258]
NTRK3 TTXABCW Strong Genetic Variation [512]
OGG1 TTRU01G Strong Genetic Variation [513]
OLFM4 TTK1CX7 Strong Altered Expression [514]
OLR1 TTKSND3 Strong Genetic Variation [515]
OPA1 TTTU49Q Strong Biomarker [516]
OXER1 TT7WBSV Strong Biomarker [266]
P2RX1 TTJW7B3 Strong Genetic Variation [517]
P2RX3 TT2THBD Strong Genetic Variation [517]
P2RX4 TT1NLOA Strong Genetic Variation [517]
P2RY1 TTA93TL Strong Genetic Variation [517]
P2RY2 TTOZHQC Strong Genetic Variation [517]
PADI4 TTQHAXM Strong Biomarker [385]
PAK1 TTFN95D Strong Biomarker [518]
PCSK2 TT46F0P Strong Genetic Variation [519]
PCSK6 TT75LN9 Strong Genetic Variation [520]
PCSK7 TTD30LY Strong Genetic Variation [521]
PDE5A TTJ0IQB Strong Biomarker [522]
PDK2 TTJGCKM Strong Altered Expression [523]
PFKFB3 TTTHMQJ Strong Biomarker [524]
PGC TT7K6AD Strong Genetic Variation [525]
PGF TT48I1Y Strong Biomarker [526]
PGR TTUV8G9 Strong Biomarker [527]
PHB TT6U071 Strong Altered Expression [338]
PIM3 TTCGOIN Strong Genetic Variation [528]
PINX1 TT4FJ3A Strong Genetic Variation [366]
PKLR TT31N4S Strong Genetic Variation [529]
PLA2G1B TT9V5JH Strong Genetic Variation [530]
PLA2G7 TTDNFMT Strong Altered Expression [531]
PLAT TTXAGYU Strong Biomarker [532]
PLCG1 TT6T4JI Strong Biomarker [533]
PLD1 TT3T17P Strong Biomarker [534]
PLG TTP86E2 Strong Altered Expression [535]
PLN TTMCVJF Strong Biomarker [536]
POR TTOQ9GZ Strong Altered Expression [537]
PPP2CA TTHTKNY Strong Biomarker [538]
PRKCB TTYPXQF Strong Biomarker [539]
PRKCD TT7A1BO Strong Altered Expression [540]
PRKCE TT57MT2 Strong Biomarker [541]
PRKCZ TTBSN0L Strong Altered Expression [542]
PRKD1 TTSLUMT Strong Altered Expression [543]
PRKG1 TT7IZSA Strong Biomarker [173]
PRMT1 TTVOJAI Strong Biomarker [544]
PRTN3 TT5MLC4 Strong Genetic Variation [545]
PSEN1 TTZ3S8C Strong Posttranslational Modification [546]
PSMB6 TT8EPLT Strong Altered Expression [547]
PTAFR TTQL5VC Strong Altered Expression [548]
PTGER3 TTPNGDE Strong Biomarker [549]
PTH1R TTFPD47 Strong Genetic Variation [366]
PTK2B TTTEFBV Strong Altered Expression [61]
PTPN2 TTY8PUS Strong Genetic Variation [181]
PYY TTVFJLX Strong Biomarker [550]
RBPJ TT72D4Z Strong Genetic Variation [551]
RORB TTGB2LZ Strong Biomarker [552]
RORC TTGV6LY Strong Biomarker [552]
RPS6KA3 TTUM2ZR Strong Biomarker [553]
RPS6KB1 TTG0U4H Strong Biomarker [554]
RXRA TT6PEUO Strong Biomarker [555]
RXRG TTH029C Strong Genetic Variation [556]
S100A8 TT4AF6N Strong Biomarker [557]
SCARB1 TTRE324 Strong Genetic Variation [558]
SCD TT6RIOV Strong Biomarker [559]
SCN8A TT54ERL Strong Genetic Variation [560]
SDC1 TTYDSVG Strong Altered Expression [561]
SELL TT2IYXF Strong Genetic Variation [562]
SELP TTE5VG0 Strong Biomarker [563]
SEMA3A TTVKD3S Strong Biomarker [564]
SERPINC1 TT4QPUL Strong Genetic Variation [565]
SERPING1 TTVQ6R9 Strong Biomarker [566]
SFRP4 TTX8I1Y Strong Biomarker [567]
SGK1 TTTV8EJ Strong Biomarker [568]
SIK2 TTCUGZR Strong Biomarker [569]
SIRT1 TTUF2HO Strong Biomarker [570]
SIRT3 TTVZLIJ Strong Altered Expression [571]
SIRT6 TTUXYWF Strong Altered Expression [572]
SLC16A1 TTN1J82 Strong Genetic Variation [573]
SLC22A1 TTM5Q4V Strong Genetic Variation [574]
SLC22A2 TT0XOJN Strong Genetic Variation [574]
SLC26A9 TTKRVU0 Strong Genetic Variation [575]
SLC29A4 TTTR957 Strong Genetic Variation [576]
SLC2A12 TTZO36H Strong Altered Expression [577]
SLC47A1 TTMHCGA Strong Biomarker [574]
SLC5A1 TT2UE56 Strong Biomarker [578]
SLC6A2 TTAWNKZ Strong Genetic Variation [579]
SLC9A1 TTGSEFH Strong Biomarker [580]
SLCO4C1 TTACFNR Strong Genetic Variation [581]
SMAD7 TT0J32Z Strong Altered Expression [582]
SMPD1 TTJTM88 Strong Biomarker [583]
SNAP25 TTYQWA0 Strong Biomarker [584]
SNCA TT08OSU Strong Biomarker [585]
SORT1 TTRX9AV Strong Genetic Variation [586]
SPHK1 TTOHFIY Strong Biomarker [587]
SRD5A1 TTTU72V Strong Biomarker [588]
SREBF2 TTRQ4AP Strong Genetic Variation [589]
SRGN TTCHB06 Strong Genetic Variation [590]
SRR TTZFUY6 Strong Genetic Variation [591]
SSTR4 TTAE1BR Strong Biomarker [299]
SSTR5 TT2BC4G Strong Biomarker [219]
STAR TTEI40H Strong Biomarker [377]
STC1 TTDLUER Strong Biomarker [592]
STK38 TT27XFN Strong Genetic Variation [593]
STS TTHM0R1 Strong Altered Expression [594]
SULF2 TTLQTHB Strong Biomarker [595]
TAAR1 TTIU98M Strong Biomarker [596]
TBK1 TTMP03S Strong Biomarker [597]
TBX21 TTNF9PH Strong Genetic Variation [598]
TGFBR2 TTZE3P7 Strong Biomarker [599]
TGM2 TT2F4OL Strong Genetic Variation [600]
THBD TTAPV67 Strong Biomarker [601]
TIRAP TTKU0LS Strong Genetic Variation [602]
TKT TT04R7I Strong Genetic Variation [603]
TLR9 TTSHG0T Strong Genetic Variation [604]
TMPRSS15 TTXL0GC Strong Biomarker [605]
TMPRSS6 TTL9KE7 Strong Genetic Variation [606]
TNFRSF18 TTG6LA7 Strong Biomarker [607]
TNFRSF1A TTG043C Strong Biomarker [608]
TNFRSF1B TT63WSF Strong Biomarker [608]
TNFRSF4 TTL31H0 Strong Altered Expression [609]
TNFSF11 TT9E8HR Strong Genetic Variation [610]
TNFSF12 TTBTDM1 Strong Altered Expression [611]
TNKS2 TTFQI4H Strong Genetic Variation [612]
TOP1 TTGTQHC Strong Biomarker [613]
TPCN2 TTHQJ2Y Strong Genetic Variation [528]
TRPA1 TTELV3W Strong Biomarker [614]
TRPC1 TTA76X0 Strong Biomarker [615]
TRPC6 TTRBT3W Strong Biomarker [616]
TRPM5 TT1N8F3 Strong Genetic Variation [617]
TRPV1 TTMI6F5 Strong Biomarker [618]
TTR TTPOYU7 Strong Altered Expression [619]
TXNRD3 TTDYFVB Strong Genetic Variation [620]
UCHL1 TTX9IFP Strong Biomarker [621]
UCP1 TTI12YJ Strong Altered Expression [622]
UGT1A1 TT34ZAF Strong Genetic Variation [623]
UNC13B TT948FC Strong Genetic Variation [624]
USP14 TTVSYP9 Strong Biomarker [625]
USP37 TTJDELN Strong Biomarker [461]
VIP TTGTWLF Strong Biomarker [626]
VIPR1 TTCL30I Strong Genetic Variation [627]
ABCA4 TTLB52K Definitive Altered Expression [628]
AKT2 TTH24WI Definitive Altered Expression [629]
APCS TTB7VAT Definitive Biomarker [630]
ATP4A TTF1QVM Definitive Biomarker [631]
BLVRA TTJBPN3 Definitive Biomarker [632]
BMP6 TT07RIB Definitive Biomarker [633]
CAMKK2 TTV298Y Definitive Genetic Variation [308]
CARM1 TTIZQFJ Definitive Altered Expression [634]
CASP8 TT6SZNG Definitive Biomarker [635]
CHN2 TT39YVO Definitive Genetic Variation [636]
CMKLR1 TT4UGZL Definitive Altered Expression [637]
CTSC TT4H0V2 Definitive Biomarker [638]
CXCR1 TTMWT8Z Definitive Genetic Variation [639]
DGAT1 TT0GV3R Definitive Biomarker [640]
ECE2 TT5U914 Definitive Genetic Variation [641]
EHMT2 TTS6RZT Definitive Genetic Variation [308]
EPHB1 TT8MDAC Definitive Genetic Variation [579]
F2RL3 TTD0652 Definitive Genetic Variation [642]
FADS2 TTT2VDU Definitive Biomarker [643]
FCGRT TTKLPHO Definitive Biomarker [478]
FDXR TT3W4IX Definitive Biomarker [644]
GJA8 TTJ7ATH Definitive Altered Expression [425]
GLP2R TT1YWO5 Definitive Genetic Variation [581]
GPER1 TTDSB34 Definitive Altered Expression [645]
GPI TT19JIZ Definitive Altered Expression [646]
GRB2 TTEYRJ9 Definitive Biomarker [647]
GRK2 TTAZ3MN Definitive Biomarker [648]
HNRNPA1 TTPJ9XK Definitive Biomarker [649]
HOXA5 TTXSVQP Definitive Biomarker [650]
HSD17B13 TTDJYZR Definitive Altered Expression [409]
IL15RA TTGN89I Definitive Biomarker [651]
IL16 TTW4R0B Definitive Genetic Variation [652]
JMJD1C TTBISK4 Definitive Genetic Variation [653]
KCNJ4 TTXF0ZW Definitive Altered Expression [654]
KCNN2 TT2T5M0 Definitive Altered Expression [655]
KCNN3 TT9JH25 Definitive Altered Expression [655]
KISS1 TTU2O6T Definitive Altered Expression [656]
LAMP1 TTC214J Definitive Altered Expression [657]
LAMP2 TTULDG7 Definitive Altered Expression [658]
LGR4 TTY6C71 Definitive Biomarker [659]
LIPG TTHSZXO Definitive Altered Expression [660]
LTBR TTFO0PM Definitive Altered Expression [661]
MAP4K4 TT6NI13 Definitive Genetic Variation [662]
MBL2 TTMQDZ5 Definitive Genetic Variation [663]
METAP2 TTZL0OI Definitive Biomarker [664]
NCAM1 TTVXPHT Definitive Biomarker [468]
NR1I2 TT7LCTF Definitive Biomarker [665]
NUCB1 TT6A5ZL Definitive Genetic Variation [666]
PAWR TT3I4WV Definitive Genetic Variation [642]
PTGDR2 TTQDMX5 Definitive Biomarker [667]
ROS1 TTSZ6Y3 Definitive Biomarker [668]
SCGB1A1 TTONPVW Definitive Biomarker [669]
SGCG TTSMT9W Definitive Genetic Variation [670]
SH2B3 TT36N7Z Definitive Genetic Variation [332]
SIK1 TT1H6LC Definitive Biomarker [671]
SIRT2 TTLKF5M Definitive Genetic Variation [672]
SLC10A2 TTPI1M5 Definitive Biomarker [673]
SLC11A2 TT2IS7P Definitive Altered Expression [674]
SLC40A1 TT6Y1PG Definitive Altered Expression [674]
SLC46A1 TTY8Z2E Definitive Biomarker [674]
SLC9A3 TTFZVPO Definitive Biomarker [675]
SLCO2B1 TTDL3UZ Definitive Altered Expression [293]
SOCS1 TT8COJM Definitive Biomarker [676]
SPHK2 TTCN0M9 Definitive Altered Expression [655]
TF TT8WXAV Definitive Biomarker [677]
TMPRSS11D TTWHYC8 Definitive Genetic Variation [678]
TNFRSF14 TTWGTC1 Definitive Altered Expression [661]
TST TT51OTS Definitive Biomarker [679]
TXNRD1 TTR7UJ3 Definitive Altered Expression [680]
UTS2 TTERU0T Definitive Altered Expression [681]
VDAC1 TTAMKGB Definitive Biomarker [682]
WRN TT2H5WQ Definitive Genetic Variation [683]
------------------------------------------------------------------------------------
⏷ Show the Full List of 741 DTT(s)
This Disease Is Related to 38 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCB6 DTF9Y2V Limited Genetic Variation [684]
ABCC8 DTI58LU Limited Autosomal dominant [685]
ATP10A DTTQ8WI Limited Biomarker [686]
SLC25A19 DTT82QK Limited Biomarker [687]
SLC2A3 DT9SQ3L Limited Altered Expression [688]
SLC30A5 DTVHQT2 Limited Altered Expression [689]
SLC30A7 DTQK38X Limited Altered Expression [689]
SLC35A1 DTVZIRG Limited Altered Expression [690]
SLC35B3 DTXC0W6 Limited Biomarker [691]
SLC39A10 DTK02RZ Limited Altered Expression [689]
SLC39A3 DTH08M7 Limited Altered Expression [689]
SLC39A7 DTDQSAM Limited Biomarker [692]
SLC41A1 DTB37ZE Limited Genetic Variation [693]
SLC41A2 DTIVJE4 Limited Genetic Variation [693]
SLC50A1 DTI9CQU Limited Genetic Variation [694]
ATP7A DT0LT17 Disputed Biomarker [695]
SLC14A2 DT8QC7K moderate Genetic Variation [696]
SLCO6A1 DTIFXNS moderate Genetic Variation [697]
ABCB9 DT68UV2 Strong Genetic Variation [73]
ABCC11 DTWN7FC Strong Altered Expression [698]
ABCC5 DTYVM24 Strong Genetic Variation [699]
ATP2B1 DTJWQ1L Strong Genetic Variation [700]
SLC17A3 DTFOJL7 Strong Genetic Variation [701]
SLC17A9 DT9BI8W Strong Altered Expression [702]
SLC25A20 DTQOUM4 Strong Biomarker [703]
SLC25A3 DTCRIWV Strong Genetic Variation [704]
SLC2A5 DTOR02F Strong Altered Expression [705]
SLC2A8 DT2I7BM Strong Altered Expression [577]
SLC30A1 DT1BO38 Strong Altered Expression [689]
SLC39A1 DTLWPXS Strong Altered Expression [689]
SLC52A1 DT7NOKR Strong Altered Expression [706]
SLC6A20 DT97OMP Strong Genetic Variation [707]
SLC9B2 DT4JZLA Strong Genetic Variation [366]
SLC9C1 DT9J8DO Strong Biomarker [708]
ATP12A DT5NLZA Definitive Biomarker [631]
SLC16A13 DTVNR7F Definitive Genetic Variation [612]
SLC16A7 DTLT3UG Definitive Biomarker [709]
SLC39A12 DT1UIT5 Definitive Biomarker [710]
------------------------------------------------------------------------------------
⏷ Show the Full List of 38 DTP(s)
This Disease Is Related to 63 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
ADH1C DEM1HNL Limited Genetic Variation [711]
ALDH3B1 DE2ZWSM Limited Genetic Variation [221]
AOC2 DE8DP90 Limited Biomarker [317]
CBR3 DEIVKZ8 Limited Genetic Variation [712]
CHST3 DEQIZP2 Limited Biomarker [713]
CYB5A DE9A2LB Limited Altered Expression [714]
CYP7A1 DEDZRQ1 Limited Altered Expression [715]
HK1 DEDMAGE Limited Genetic Variation [716]
HSD17B10 DEGSPC9 Limited Genetic Variation [717]
MAT1A DEQ6NC9 Limited Biomarker [718]
ME1 DE97WM8 Limited Biomarker [719]
NT5C2 DE1DOKJ Limited Biomarker [720]
PER1 DE9HF0I Limited Genetic Variation [721]
PGM1 DEA3VM1 Limited Genetic Variation [722]
PMM2 DEBRX3L Limited Biomarker [723]
SAT1 DEMWO83 Limited Genetic Variation [724]
SCLY DEH4TD6 Limited Biomarker [725]
SULT1E1 DESTKG6 Limited Altered Expression [726]
TGM2 DEF75S0 Limited Autosomal dominant [727]
TKFC DEX9ZJQ Limited Biomarker [728]
UGT1A10 DEL5N6Y Limited Genetic Variation [623]
UGT1A3 DEF2WXN Limited Genetic Variation [623]
UGT1A4 DELOY3P Limited Genetic Variation [623]
UGT1A5 DEPF954 Limited Genetic Variation [623]
UGT1A7 DEZO4N3 Limited Genetic Variation [623]
UGT1A8 DE2GB8N Limited Genetic Variation [623]
UGT1A9 DE85D2P Limited Genetic Variation [623]
CYP2C18 DEZMWRE moderate Biomarker [379]
UBASH3B DE10BJ5 moderate Genetic Variation [729]
ABO DESIA7R Strong Biomarker [730]
ACOT2 DEMEPVJ Strong Biomarker [731]
ADH1B DEEN9RD Strong Genetic Variation [732]
AKR1A1 DED2FW3 Strong Biomarker [733]
APRT DE2MV1R Strong Altered Expression [734]
CHDH DEAHED0 Strong Genetic Variation [265]
CYP27A1 DEBS639 Strong Genetic Variation [735]
CYP2C8 DES5XRU Strong Genetic Variation [736]
CYP2R1 DEBIHM3 Strong Genetic Variation [737]
CYP4F3 DEFCMPI Strong Biomarker [379]
DDAH1 DEY0TQC Strong Genetic Variation [738]
DHCR7 DEL7GFA Strong Genetic Variation [739]
FADS1 DE05S8C Strong Biomarker [740]
GGCT DEKW6PB Strong Genetic Variation [741]
GLS DE3E0VT Strong Biomarker [742]
GNPDA2 DEPJGQB Strong Genetic Variation [743]
GSTA4 DEH7XYP Strong Altered Expression [744]
HSD17B12 DE915QP Strong Genetic Variation [581]
HSD17B3 DEX8J7E Strong Biomarker [377]
HSD3B1 DERDQWN Strong Biomarker [377]
MSMO1 DE5FUD0 Strong Biomarker [643]
MT2A DEFKGT7 Strong Genetic Variation [606]
NNMT DECVGJ3 Strong Altered Expression [745]
PCYT1A DEQYXD4 Strong Genetic Variation [746]
PSAT1 DEBS17P Strong Biomarker [467]
SI DE5EO4Y Strong Biomarker [486]
UGT1A6 DESD26P Strong Genetic Variation [623]
UGT2B15 DENZ6B1 Strong Genetic Variation [747]
AKR1C2 DEOY5ZM Definitive Altered Expression [748]
CYP8B1 DETL4WB Definitive Altered Expression [749]
GCLC DESYL1F Definitive Biomarker [750]
GFPT2 DERQCJM Definitive Altered Expression [751]
MT1A DE5ME8A Definitive Altered Expression [689]
UPP2 DEBQ2WU Definitive Genetic Variation [752]
------------------------------------------------------------------------------------
⏷ Show the Full List of 63 DME(s)

References

1 Acarbose FDA Label
2 Atorvastatin FDA Label
3 Canagliflozin FDA Label
4 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6801).
5 Dapagliflozin FDA Label
6 Exenatide FDA Label
7 Spectroscopic interactions of non-insulin-dependent diabetes mellitus with levocetirizine. Pak J Pharm Sci. 2021 Jul;34(4(Supplementary)):1639-1644.
8 Bepridil, an antiarrhythmic drug, opens mitochondrial KATP channels, blocks sarcolemmal KATP channels, and confers cardioprotection. J Pharmacol Exp Ther. 2006 Jan;316(1):182-8.
9 Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial. JAMA. 2022 Feb 8;327(6):534-545.
10 Diabetes mellitus: complications and therapeutics. Med Sci Monit. 2006 Jul;12(7):RA130-47. Epub 2006 Jun 28.
11 Linagliptin FDA Label
12 Liraglutide FDA Label
13 Metformin FDA Label
14 Pioglitazone FDA Label
15 Inhibitors can arrest the membrane activity of human islet amyloid polypeptide independently of amyloid formation. FEBS Lett. 2001 Oct 26;507(2):200-4.
16 Sitagliptin FDA Label
17 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
18 Effects of combination therapy with mitiglinide and voglibose on postprandial plasma glucose in patients with type 2 diabetes mellitus. Diabetes Metab Syndr Obes. 2013 Sep 2;6:317-25.
19 Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains. Endocrinology. 2003 Nov;144(11):4755-62.
20 ClinicalTrials.gov (NCT01370707) A Study to Evaluate the Efficacy and Safety of CJ-30001 and CJ-30002 in Type 2 Diabetes Mellitus Patients. U.S. National Institutes of Health.
21 ClinicalTrials.gov (NCT00256867) A Study In Patients With Type 2 Diabetes Mellitus. U.S. National Institutes of Health.
22 A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
23 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1612).
24 Oral and i.v. pharmacokinetics of isosteviol in rats as assessed by a new sensitive LC-MS/MS method. J Pharm Biomed Anal. 2008 Nov 4;48(3):986-90.
25 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 251).
26 ClinicalTrials.gov (NCT01386541) Multiple Ascending Dose Trial of BYK324677 in Healthy Volunteers. U.S. National Institutes of Health.
27 ClinicalTrials.gov (NCT01253278) A Multiple-Ascending Dose Study in Type 2 Diabetes Mellitus Patients. U.S. National Institutes of Health.
28 ClinicalTrials.gov (NCT00943371) A Single-Dose Study of MK6349 in Patients With Type 2 Diabetes (6349-002). U.S. National Institutes of Health.
29 ClinicalTrials.gov (NCT01183715) A Single Dose Study Of PF-05161704 In Healthy Volunteers. U.S. National Institutes of Health.
30 ClinicalTrials.gov (NCT00961909) A Study of RO5095932 in Patients With Type 2 Diabetes Mellitus. U.S. National Institutes of Health.
31 ClinicalTrials.gov (NCT00887445) First in Man Study With SLV341. U.S. National Institutes of Health.
32 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015111)
33 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031487)
34 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032165)
35 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011869)
36 ClinicalTrials.gov (NCT01087645) A Two Part Trial Investigating the Safety of NN9925 in Healthy Male Subjects. U.S. National Institutes of Health.
37 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025590)
38 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010251)
39 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026093)
40 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016460)
41 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016461)
42 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009166)
43 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
44 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 126).
45 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5723).
46 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 443).
47 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
48 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 249).
49 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2763).
50 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 225).
51 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1800).
52 Medicinal chemistry approaches to the inhibition of dipeptidyl peptidase-4 for the treatment of type 2 diabetes. Bioorg Med Chem. 2009 Mar 1;17(5):1783-802.
53 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2798).
54 WFS1 Gene-associated Diabetes Phenotypes and Identification of a Founder Mutation in Southern India. J Clin Endocrinol Metab. 2022 Apr 19;107(5):1328-1336. doi: 10.1210/clinem/dgac002.
55 Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene.Diabetes. 1998 Apr;47(4):598-605. doi: 10.2337/diabetes.47.4.598.
56 Increased urinary angiotensin converting enzyme 2 and neprilysin in patients with type 2 diabetes.Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F263-F274. doi: 10.1152/ajprenal.00565.2017. Epub 2018 Mar 21.
57 The ADRA2A rs553668 variant is associated with type 2 diabetes and five variants were associated at nominal significance levels in a population-based case-control study from Mexico City.Gene. 2018 Aug 30;669:28-34. doi: 10.1016/j.gene.2018.05.078. Epub 2018 May 22.
58 Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.PLoS Genet. 2012;8(2):e1002490. doi: 10.1371/journal.pgen.1002490. Epub 2012 Feb 16.
59 Associations of statins and antiretroviral drugs with the onset of type 2 diabetes among HIV-1-infected patients.BMC Infect Dis. 2017 Jan 7;17(1):43. doi: 10.1186/s12879-016-2099-5.
60 Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Mller Cells of Diabetic Human and Rodent Retina.Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5043-5055. doi: 10.1167/iovs.17-21654.
61 Effect of combination of chlorella intake and aerobic exercise training on glycemic control in type 2 diabetic rats.Nutrition. 2019 Jul-Aug;63-64:45-50. doi: 10.1016/j.nut.2019.01.008. Epub 2019 Jan 24.
62 A family with severe insulin resistance and diabetes due to a mutation in AKT2. Science. 2004 May 28;304(5675):1325-8. doi: 10.1126/science.1096706.
63 Gene prioritization based on biological plausibility over genome wide association studies renders new loci associated with type 2 diabetes.Genet Med. 2009 May;11(5):338-43. doi: 10.1097/GIM.0b013e31819995ca.
64 ALCAM a novel biomarker in patients with type 2 diabetes mellitus complicated with diabetic nephropathy.J Diabetes Complications. 2017 Jun;31(6):1058-1065. doi: 10.1016/j.jdiacomp.2017.01.002. Epub 2017 Jan 21.
65 Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes.Front Immunol. 2019 Mar 27;10:571. doi: 10.3389/fimmu.2019.00571. eCollection 2019.
66 ARG1 single nucleotide polymorphisms rs2781666 and rs2781665 confer risk of Type 2 diabetes mellitus.EXCLI J. 2018 Aug 27;17:847-855. doi: 10.17179/excli2018-1178. eCollection 2018.
67 Cross-talk between apelin and vasopressin in response to different osmotic stimuli in type 2 diabetic rats.J Biol Regul Homeost Agents. 2018 Sep-Oct;32(5):1117-1127.
68 Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression.Obesity (Silver Spring). 2013 Dec;21(12):E626-33. doi: 10.1002/oby.20482. Epub 2013 Jul 5.
69 Identification of novel candidate genes for type 2 diabetes from a genome-wide association scan in the Old Order Amish: evidence for replication from diabetes-related quantitative traits and from independent populations.Diabetes. 2007 Dec;56(12):3053-62. doi: 10.2337/db07-0457. Epub 2007 Sep 10.
70 Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic effects.J Pharmacol Exp Ther. 2006 Dec;319(3):1144-52. doi: 10.1124/jpet.106.107482. Epub 2006 Sep 7.
71 ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan.Diabetes. 2009 Sep;58(9):2018-26. doi: 10.2337/db09-0206. Epub 2009 Jun 5.
72 Natural antibiotics and insulin sensitivity: the role of bactericidal/permeability-increasing protein.Diabetes. 2006 Jan;55(1):216-24.
73 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.Nat Genet. 2017 Oct;49(10):1450-1457. doi: 10.1038/ng.3943. Epub 2017 Sep 4.
74 Brd2 gene disruption causes "metabolically healthy" obesity: epigenetic and chromatin-based mechanisms that uncouple obesity from type 2 diabetes.Vitam Horm. 2013;91:49-75. doi: 10.1016/B978-0-12-407766-9.00003-1.
75 Association of Complement C5 Gene Polymorphisms with Proliferative Diabetic Retinopathy of Type 2 Diabetes in a Chinese Han Population.PLoS One. 2016 Mar 2;11(3):e0149704. doi: 10.1371/journal.pone.0149704. eCollection 2016.
76 The silent PPARgamma exon 6 CAC(His) --> CAT(His) polymorphism does not affect the plasma leptin levels in a collective of first degree relatives of type 2 diabetes patients from South West Germany.Exp Clin Endocrinol Diabetes. 2000;108(5):341-6. doi: 10.1055/s-2000-8126.
77 The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes.Diabetologia. 2013 Feb;56(2):340-9. doi: 10.1007/s00125-012-2758-z. Epub 2012 Nov 15.
78 Identifying heterogeneous subtypes of gastric cancer and subtypespecific subpaths of microRNAtarget pathways.Mol Med Rep. 2018 Mar;17(3):3583-3590. doi: 10.3892/mmr.2017.8329. Epub 2017 Dec 20.
79 Proteomics of the Rat Myocardium during Development of Type 2 Diabetes Mellitus Reveals Progressive Alterations in Major Metabolic Pathways.J Proteome Res. 2018 Jul 6;17(7):2521-2532. doi: 10.1021/acs.jproteome.8b00276. Epub 2018 Jun 15.
80 Hypothesis and Theory: Circulating Alzheimer's-Related Biomarkers in Type 2 Diabetes. Insight From the Goto-Kakizaki Rat.Front Neurol. 2019 Jun 26;10:649. doi: 10.3389/fneur.2019.00649. eCollection 2019.
81 Plasma Connective Tissue Growth Factor (CTGF/CCN2) Levels Predict Myocardial Infarction in the Veterans Affairs Diabetes Trial (VADT) Cohort.Diabetes Care. 2018 Apr;41(4):840-846. doi: 10.2337/dc17-2083. Epub 2018 Jan 30.
82 Definition of a Skp2-c-Myc Pathway to Expand Human Beta-cells.Sci Rep. 2016 Jul 6;6:28461. doi: 10.1038/srep28461.
83 The effect of very-low-calorie diet on mRNA expression of inflammation-related genes in subcutaneous adipose tissue and peripheral monocytes of obese patients with type 2 diabetes mellitus.J Clin Endocrinol Metab. 2011 Apr;96(4):E606-13. doi: 10.1210/jc.2010-1858. Epub 2011 Feb 2.
84 Key determinants of selective binding and activation by the monocyte chemoattractant proteins at the chemokine receptor CCR2.Sci Signal. 2017 May 23;10(480):eaai8529. doi: 10.1126/scisignal.aai8529.
85 IRS1- rs10498210 G/A and CCR5-59029 A/G polymorphisms in patients with type 2 diabetes in Kurdistan.Mol Genet Genomic Med. 2019 May;7(5):e631. doi: 10.1002/mgg3.631. Epub 2019 Mar 18.
86 Increased and decreased relative risk for non-insulin-dependent diabetes mellitus conferred by HLA class II and by CD4 alleles.Clin Genet. 1995 May;47(5):225-30. doi: 10.1111/j.1399-0004.1995.tb04301.x.
87 Butyrylcholinesterase K variants increase the risk of coronary artery disease in the population of western Iran.Scand J Clin Lab Invest. 2008;68(2):123-9. doi: 10.1080/00365510701576180. Epub 2007 Nov 21.
88 The serum levels of tumor marker CA19-9, CEA, CA72-4, and NSE in type 2 diabetes without malignancy and the relations to the metabolic control.Saudi Med J. 2017 Feb;38(2):204-208. doi: 10.15537/smj.2017.2.15649.
89 Construction of adiponectin-encoding plasmid DNA and gene therapy of non-obese type 2 diabetes mellitus.J Drug Target. 2010 Jan;18(1):67-77. doi: 10.3109/10611860903225719.
90 Relationship between retinol and risk of diabetic retinopathy: a case-control study.Asia Pac J Clin Nutr. 2019;28(3):607-613. doi: 10.6133/apjcn.201909_28(3).0021.
91 MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes.Cell Rep. 2016 Mar 1;14(8):1991-2002. doi: 10.1016/j.celrep.2016.02.002. Epub 2016 Feb 18.
92 Mutation in the beta3 subunit of Guanine nucleotide-binding protein (GNB3) gene is not associated with Type II diabetes mellitus risk: a case-control study of a North Indian population.Biomarkers. 2017 Dec;22(8):782-789. doi: 10.1080/1354750X.2017.1340974. Epub 2017 Jul 11.
93 Adipose tissue collagen VI in obesity.J Clin Endocrinol Metab. 2009 Dec;94(12):5155-62. doi: 10.1210/jc.2009-0947. Epub 2009 Oct 16.
94 Development and validation of a Health Policy Model of Type 2 diabetes in Chinese setting.J Comp Eff Res. 2018 Aug;7(8):749-763. doi: 10.2217/cer-2018-0001. Epub 2018 Aug 22.
95 Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus.Metabolism. 2012 Feb;61(2):175-85. doi: 10.1016/j.metabol.2011.06.014. Epub 2011 Aug 3.
96 ER and/or ER activation ameliorates cognitive impairment, neurogenesis and apoptosis in type 2 diabetes mellitus mice.Exp Neurol. 2019 Jan;311:33-43. doi: 10.1016/j.expneurol.2018.09.002. Epub 2018 Sep 7.
97 Glucose-Raising Polymorphisms in the Human Clock Gene Cryptochrome 2 (CRY2) Affect Hepatic Lipid Content.PLoS One. 2016 Jan 4;11(1):e0145563. doi: 10.1371/journal.pone.0145563. eCollection 2016.
98 Genetic association of Glutathione peroxidase-1 (GPx-1) and NAD(P)H:Quinone Oxidoreductase 1(NQO1) variants and their association of CAD in patients with type-2 diabetes.Mol Cell Biochem. 2012 Feb;361(1-2):143-50. doi: 10.1007/s11010-011-1098-5. Epub 2011 Oct 12.
99 The effect of very-low-calorie diet on mitochondrial dysfunction in subcutaneous adipose tissue and peripheral monocytes of obese subjects with type 2 diabetes mellitus.Physiol Res. 2017 Nov 24;66(5):811-822. doi: 10.33549/physiolres.933469. Epub 2017 Jul 18.
100 Sex-specific differences in effect size estimates at established complex trait loci.Int J Epidemiol. 2012 Oct;41(5):1376-82. doi: 10.1093/ije/dys104. Epub 2012 Jul 23.
101 Hepatic expression of cytochrome P450 in type 2 diabetic Goto-Kakizaki rats.Chem Biol Interact. 2012 Feb 5;195(3):173-9. doi: 10.1016/j.cbi.2011.12.010. Epub 2012 Jan 5.
102 Interaction between heavy smoking and CYP2A6 genotypes on type 2 diabetes and its possible pathways.Eur J Endocrinol. 2011 Dec;165(6):961-7. doi: 10.1530/EJE-11-0596. Epub 2011 Sep 29.
103 The influence of dopamine-beta-hydroxylase and catechol O-methyltransferase gene polymorphism on the efficacy of insulin detemir therapy in patients with type 2 diabetes mellitus.Diabetol Metab Syndr. 2017 Dec 4;9:97. doi: 10.1186/s13098-017-0295-0. eCollection 2017.
104 Overexpressions of hBD-2, hBD-3, and hCAP18/LL-37 in Gingiva of Diabetics with Periodontitis.Immunobiology. 2015 Nov;220(11):1219-26. doi: 10.1016/j.imbio.2015.06.013. Epub 2015 Jun 10.
105 Association of DRD3, COMT, and SLC6A4 Gene Polymorphisms with Type 2 Diabetes in Southern Chinese: A Hospital-Based Case-Control Study.Diabetes Technol Ther. 2015 Aug;17(8):580-6. doi: 10.1089/dia.2014.0344. Epub 2015 Apr 30.
106 Improving Assessment of the Spectrum of Reward-Related Eating: The RED-13.Front Psychol. 2017 May 30;8:795. doi: 10.3389/fpsyg.2017.00795. eCollection 2017.
107 Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex.Nature. 2009 Aug 27;460(7259):1154-8. doi: 10.1038/nature08262. Epub 2009 Jul 29.
108 Hypoglycemic Effects in Alloxan-Induced Diabetic Rats of the Phenolic Extract from Mongolian Oak Cups Enriched in Ellagic Acid, Kaempferol and Their Derivatives.Molecules. 2018 Apr 30;23(5):1046. doi: 10.3390/molecules23051046.
109 Serum Uric Acid Levels were Dynamically Coupled with Hemoglobin A1c in the Development of Type 2 Diabetes.Sci Rep. 2016 Jun 22;6:28549. doi: 10.1038/srep28549.
110 PREVALENCE OF DIABETES IN GREATER BEIRUT AREA: WORSENING OVER TIME.Endocr Pract. 2017 Sep;23(9):1091-1100. doi: 10.4158/EP171876.OR. Epub 2017 Jul 6.
111 Effect of common polymorphisms in the HNF4alpha promoter on susceptibility to type 2 diabetes in the French Caucasian population.Diabetologia. 2005 Mar;48(3):440-4. doi: 10.1007/s00125-004-1665-3. Epub 2005 Feb 25.
112 Orphan nuclear receptor estrogen-related receptor (ERR) is key regulator of hepatic gluconeogenesis.J Biol Chem. 2012 Jun 22;287(26):21628-39. doi: 10.1074/jbc.M111.315168. Epub 2012 May 1.
113 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.Nat Genet. 2019 Mar;51(3):379-386. doi: 10.1038/s41588-018-0332-4. Epub 2019 Feb 4.
114 Factor V G1691A, prothrombin G20210A and methylenetetrahydrofolate reductase polymorphism C677T are not associated with coronary artery disease and type 2 diabetes mellitus in western Iran.Blood Coagul Fibrinolysis. 2009 Jun;20(4):252-6. doi: 10.1097/MBC.0b013e3283255487.
115 Polymorphisms in fatty acid-binding protein-3 (FABP3) - putative association with type 2 diabetes mellitus.Hum Mutat. 2003 Aug;22(2):180. doi: 10.1002/humu.9168.
116 Polymorphisms in fatty acid binding protein 5 show association with type 2 diabetes.Diabetes Res Clin Pract. 2011 Apr;92(1):82-91. doi: 10.1016/j.diabres.2011.01.005. Epub 2011 Feb 1.
117 Antibodies Against the C-Terminus of ApoA-1 Are Inversely Associated with Cholesterol Efflux Capacity and HDL Metabolism in Subjects with and without Type 2 Diabetes Mellitus.Int J Mol Sci. 2019 Feb 9;20(3):732. doi: 10.3390/ijms20030732.
118 Liver-derived fibroblast growth factor 21 mediates effects of glucagon-like peptide-1 in attenuating hepatic glucose output.EBioMedicine. 2019 Mar;41:73-84. doi: 10.1016/j.ebiom.2019.02.037. Epub 2019 Mar 1.
119 Association between Adipose Tissue Interleukin-33 and Immunometabolic Markers in Individuals with Varying Degrees of Glycemia.Dis Markers. 2019 Apr 3;2019:7901062. doi: 10.1155/2019/7901062. eCollection 2019.
120 A polymorphism within the fructosamine-3-kinase gene is associated with HbA1c Levels and the onset of type 2 diabetes mellitus.Exp Clin Endocrinol Diabetes. 2010 Mar;118(3):209-12. doi: 10.1055/s-0029-1238319. Epub 2009 Oct 15.
121 Multi-target antidiabetic mechanisms of mexicanolides from Swietenia humilis.Phytomedicine. 2019 May;58:152891. doi: 10.1016/j.phymed.2019.152891. Epub 2019 Mar 13.
122 GTP cyclohydrolase I gene polymorphisms are associated with endothelial dysfunction and oxidative stress in patients with type 2 diabetes mellitus.PLoS One. 2014 Nov 4;9(11):e108587. doi: 10.1371/journal.pone.0108587. eCollection 2014.
123 Diversity and association of HLA/KIR receptors with type 2 diabetes in South India.Int J Immunogenet. 2019 Jun;46(3):166-178. doi: 10.1111/iji.12417. Epub 2019 Feb 27.
124 Genetic risk for coronary artery disease in individuals with or without type 2 diabetes.Mol Genet Metab. 2004 Apr;81(4):282-90. doi: 10.1016/j.ymgme.2004.01.014.
125 Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression.Hum Mol Genet. 2009 Feb 1;18(3):428-39. doi: 10.1093/hmg/ddn370. Epub 2008 Nov 10.
126 Differential expression of islet glutaredoxin 1 and 5 with high reactive oxygen species production in a mouse model of diabesity.PLoS One. 2017 May 24;12(5):e0176267. doi: 10.1371/journal.pone.0176267. eCollection 2017.
127 beta Cell autoimmunity in a child with M.O.D.Y. (Maturity Onset Diabetes in the Young).Diabetes Metab. 2001 Feb;27(1):59-61.
128 Surface expression of collagen receptor Fc receptor-gamma/glycoprotein VI is enhanced on platelets in type 2 diabetes and mediates release of CD40 ligand and activation of endothelial cells.Diabetes. 2004 Aug;53(8):2117-21. doi: 10.2337/diabetes.53.8.2117.
129 Identification and functional analysis of mutations in FAD-binding domain of mitochondrial glycerophosphate dehydrogenase in caucasian patients with type 2 diabetes mellitus.Endocrine. 2001 Oct;16(1):39-42. doi: 10.1385/ENDO:16:1:39.
130 9- and 13-HODE regulate fatty acid binding protein-4 in human macrophages, but does not involve HODE/GPR132 axis in PPAR- regulation of FABP4.Ther Adv Endocrinol Metab. 2018 May;9(5):137-150. doi: 10.1177/2042018818759894. Epub 2018 Feb 27.
131 Population genetics of CAPN10 and GPR35: implications for the evolution of type 2 diabetes variants.Am J Hum Genet. 2005 Apr;76(4):548-60. doi: 10.1086/428784. Epub 2005 Feb 4.
132 Association between progranulin serum levels and dietary intake.PLoS One. 2018 Aug 17;13(8):e0202149. doi: 10.1371/journal.pone.0202149. eCollection 2018.
133 Dendrobium huoshanense polysaccharide regulates hepatic glucose homeostasis and pancreatic -cell function in type 2 diabetic mice.Carbohydr Polym. 2019 May 1;211:39-48. doi: 10.1016/j.carbpol.2019.01.101. Epub 2019 Jan 31.
134 Glutathione S-transferase A1 polymorphism as a risk factor for smoking-related type 2 diabetes among Japanese.Toxicol Lett. 2008 May 30;178(3):143-5. doi: 10.1016/j.toxlet.2008.03.004. Epub 2008 Mar 15.
135 Involvement of the Niacin Receptor GPR109a in the LocalControl of Glucose Uptake in Small Intestine of Type 2Diabetic Mice.Nutrients. 2015 Sep 8;7(9):7543-61. doi: 10.3390/nu7095352.
136 Hyperpolarization-activated cyclic nucleotide-gated 2 (HCN2) ion channels drive pain in mouse models of diabetic neuropathy.Sci Transl Med. 2017 Sep 27;9(409):eaam6072. doi: 10.1126/scitranslmed.aam6072.
137 HDAC3 inhibition prevents blood-brain barrier permeability through Nrf2 activation in type 2 diabetes male mice.J Neuroinflammation. 2019 May 17;16(1):103. doi: 10.1186/s12974-019-1495-3.
138 MC1568 improves insulin secretion in islets from type 2 diabetes patients and rescues -cell dysfunction caused by Hdac7 upregulation.Acta Diabetol. 2018 Dec;55(12):1231-1235. doi: 10.1007/s00592-018-1201-4. Epub 2018 Aug 7.
139 Effect of saxagliptin on the expression of HIF-1 in the liver of diabetic rats with fatty liver.Exp Ther Med. 2018 Sep;16(3):2559-2563. doi: 10.3892/etm.2018.6473. Epub 2018 Jul 18.
140 Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction.Mol Cell Endocrinol. 2013 Mar 10;367(1-2):1-10. doi: 10.1016/j.mce.2012.12.001. Epub 2012 Dec 12.
141 Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice. Nat Med. 2005 Jul;11(7):765-73. doi: 10.1038/nm1254. Epub 2005 May 29.
142 Description of a second microsatellite marker and linkage analysis of the muscle glycogen synthase locus in familial NIDDM.Diabetes. 1994 Aug;43(8):1061-5. doi: 10.2337/diab.43.8.1061.
143 Longer HSD11B2 CA-repeat in impaired glucose tolerance and type 2 diabetes.Endocr J. 2013;60(5):671-8. doi: 10.1507/endocrj.ej12-0108. Epub 2013 Jan 26.
144 Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes.Diabetes. 2005 Sep;54(9):2755-63. doi: 10.2337/diabetes.54.9.2755.
145 Pancreatic -cell-specific deletion of insulin-degrading enzyme leads to dysregulated insulin secretion and -cell functional immaturity.Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E805-E819. doi: 10.1152/ajpendo.00040.2019. Epub 2019 Sep 3.
146 IL28B gene variants and glucose metabolism in Type 2 Diabetes.Hum Immunol. 2016 Dec;77(12):1280-1283. doi: 10.1016/j.humimm.2016.09.007. Epub 2016 Sep 21.
147 Elevated serum preptin concentrations in patients with diabetic nephropathy.J Investig Med. 2019 Oct;67(7):1048-1052. doi: 10.1136/jim-2019-000985. Epub 2019 Jun 9.
148 Association of sequence variations in the gene encoding insulin-like growth factor binding protein 5 with adiponectin.Int J Obes (Lond). 2009 Jan;33(1):80-8. doi: 10.1038/ijo.2008.196. Epub 2008 Oct 28.
149 Association of IL-4 receptor gene polymorphisms with high density lipoprotein cholesterol.Cytokine. 2012 Aug;59(2):309-12. doi: 10.1016/j.cyto.2012.04.023. Epub 2012 May 24.
150 An exploratory study of the association between KCNB1 rs1051295 and type 2 diabetes and its related traits in Chinese Han population.PLoS One. 2013;8(2):e56365. doi: 10.1371/journal.pone.0056365. Epub 2013 Feb 19.
151 KCNQ1 gene variants and risk of new-onset diabetes in tacrolimus-treated renal-transplanted patients.Clin Transplant. 2011 May-Jun;25(3):E284-91. doi: 10.1111/j.1399-0012.2011.01417.x. Epub 2011 Mar 1.
152 Molecular analysis of KCNJ10 on 1q as a candidate gene for Type 2 diabetes in Pima Indians.Diabetes. 2002 Nov;51(11):3342-6. doi: 10.2337/diabetes.51.11.3342.
153 Metformin diminishes the unfavourable impact of Nrf2 in breast cancer patients with type 2 diabetes.Tumour Biol. 2019 Jan;41(1):1010428318815413. doi: 10.1177/1010428318815413.
154 KLK5 induces shedding of DPP4 from circulatory Th17 cells in type 2 diabetes.Mol Metab. 2017 Nov;6(11):1529-1539. doi: 10.1016/j.molmet.2017.09.004. Epub 2017 Sep 27.
155 Development of GMDR-GPU for gene-gene interaction analysis and its application to WTCCC GWAS data for type 2 diabetes.PLoS One. 2013 Apr 23;8(4):e61943. doi: 10.1371/journal.pone.0061943. Print 2013.
156 Whole-Exome Sequencing Suggests LAMB3 as a Susceptibility Gene for Morbid Obesity.Diabetes. 2016 Oct;65(10):2980-9. doi: 10.2337/db16-0522. Epub 2016 Jul 18.
157 Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography.J Hum Genet. 2012 May;57(5):305-10. doi: 10.1038/jhg.2012.21. Epub 2012 Mar 1.
158 The polymorphism in the let-7 targeted region of the Lin28 gene is associated with increased risk of type 2 diabetes mellitus.Mol Cell Endocrinol. 2013 Aug 15;375(1-2):53-7. doi: 10.1016/j.mce.2013.04.022. Epub 2013 May 6.
159 Cilostazol, a potent phosphodiesterase type III inhibitor, selectively increases antiatherogenic high-density lipoprotein subclass LpA-I and improves postprandial lipemia in patients with type 2 diabetes mellitus.Metabolism. 2002 Oct;51(10):1348-54. doi: 10.1053/meta.2002.35191.
160 Study of lactoferrin gene expression in human and mouse adipose tissue, human preadipocytes and mouse 3T3-L1 fibroblasts. Association with adipogenic and inflammatory markers.J Nutr Biochem. 2013 Jul;24(7):1266-75. doi: 10.1016/j.jnutbio.2012.10.002. Epub 2013 Jan 17.
161 Integrating genetic association, genetics of gene expression, and single nucleotide polymorphism set analysis to identify susceptibility Loci for type 2 diabetes mellitus.Am J Epidemiol. 2012 Sep 1;176(5):423-30. doi: 10.1093/aje/kws123. Epub 2012 Aug 2.
162 Identification of haplotype tag SNPs within the whole myeloid differentiation 2 gene and their clinical relevance in patients with major trauma.Shock. 2012 Apr;37(4):366-72. doi: 10.1097/SHK.0b013e3182498c8f.
163 Salivary protective factors in patients suffering from decompensated type 2 diabetes.Adv Med Sci. 2017 Sep;62(2):211-215. doi: 10.1016/j.advms.2016.06.005. Epub 2017 May 12.
164 Variants in KCNQ1, AP3S1, MAN2A1, and ALDH7A1 and the risk of type 2 diabetes in the Chinese Northern Han population: a case-control study and meta-analysis.Med Sci Monit. 2010 Jun;16(6):BR179-83.
165 Circulating mesencephalic astrocyte-derived neurotrophic factor is increased in newly diagnosed prediabetic and diabetic patients, and is associated with insulin resistance.Endocr J. 2017 Apr 29;64(4):403-410. doi: 10.1507/endocrj.EJ16-0472. Epub 2017 Feb 17.
166 Large triglyceride-rich lipoproteins from fasting patients with type 2 diabetes activate platelets.Diabetes Metab. 2020 Feb;46(1):54-60. doi: 10.1016/j.diabet.2019.03.002. Epub 2019 Apr 11.
167 Liraglutide combined with human umbilical cord mesenchymal stem cell transplantation inhibits beta-cell apoptosis via mediating the ASK1/JNK/BAX pathway in rats with type 2 diabetes.Diabetes Metab Res Rev. 2020 Feb;36(2):e3212. doi: 10.1002/dmrr.3212. Epub 2019 Sep 2.
168 Ghrelin Reduces TNF--Induced Human Hepatocyte Apoptosis, Autophagy, and Pyroptosis: Role in Obesity-Associated NAFLD.J Clin Endocrinol Metab. 2019 Jan 1;104(1):21-37. doi: 10.1210/jc.2018-01171.
169 Further evidence for the role of ENPP1 in obesity: association with morbid obesity in Finns.Obesity (Silver Spring). 2008 Sep;16(9):2113-9. doi: 10.1038/oby.2008.313.
170 Cell-based assay of MGAT2-driven diacylglycerol synthesis for profiling inhibitors: use of a stable isotope-labeled substrate and high-resolution LC/MS.J Lipid Res. 2015 Mar;56(3):747-753. doi: 10.1194/jlr.D055020. Epub 2015 Jan 18.
171 Inhibition of MGAT2 modulates fat-induced gut peptide release and fat intake in normal mice and ameliorates obesity and diabetes in ob/ob mice fed on a high-fat diet.FEBS Open Bio. 2020 Mar;10(3):316-326. doi: 10.1002/2211-5463.12778. Epub 2020 Feb 5.
172 Differential DNA methylation of MSI2 and its correlation with diabetic traits.PLoS One. 2017 May 24;12(5):e0177406. doi: 10.1371/journal.pone.0177406. eCollection 2017.
173 Bioactive compounds in plant materials for the prevention of diabetesand obesity.Biosci Biotechnol Biochem. 2019 Jun;83(6):975-985. doi: 10.1080/09168451.2019.1580560. Epub 2019 Feb 17.
174 Single-nucleotide polymorphisms in chromosome 3p14.1- 3p14.2 are associated with susceptibility of type 2 diabetes with cataract.Mol Vis. 2010 Jul 1;16:1206-14.
175 Short-term intravenous insulin infusion is associated with reduced expression of NADPH oxidase p47(phox) subunit in monocytes from type 2 diabetes patients.Fundam Clin Pharmacol. 2013 Dec;27(6):669-71. doi: 10.1111/j.1472-8206.2012.01057.x. Epub 2012 Jul 10.
176 Natural killer cell function, an important target for infection and tumor protection, is impaired in type 2 diabetes.PLoS One. 2013 Apr 25;8(4):e62418. doi: 10.1371/journal.pone.0062418. Print 2013.
177 NOD1 activation in cardiac fibroblasts induces myocardial fibrosis in a murine model of type 2 diabetes.Biochem J. 2017 Feb 1;474(3):399-410. doi: 10.1042/BCJ20160556. Epub 2016 Nov 1.
178 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.Am J Hum Genet. 2019 Jan 3;104(1):65-75. doi: 10.1016/j.ajhg.2018.11.008. Epub 2018 Dec 27.
179 Insulin up-regulates natriuretic peptide clearance receptor expression in the subcutaneous fat depot in obese subjects: a missing link between CVD risk and obesity?.J Clin Endocrinol Metab. 2012 May;97(5):E731-9. doi: 10.1210/jc.2011-2839. Epub 2012 Mar 14.
180 Impact of natriuretic peptide clearance receptor (NPR3) gene variants on blood pressure in type 2 diabetes.Diabetes Care. 2011 May;34(5):1199-204. doi: 10.2337/dc10-2057. Epub 2011 Apr 4.
181 Design, synthesis, biological evaluation and molecular dynamics studies of 4-thiazolinone derivatives as protein tyrosine phosphatase 1B (PTP1B) inhibitors.J Biomol Struct Dyn. 2020 Aug;38(13):3814-3824. doi: 10.1080/07391102.2019.1664333. Epub 2019 Sep 19.
182 Decreased expression levels of Nurr1 are associated with chronic inflammation in patients with type 2 diabetes.Mol Med Rep. 2015 Oct;12(4):5487-93. doi: 10.3892/mmr.2015.4105. Epub 2015 Jul 21.
183 Review: the Roles and Mechanisms of Glycoprotein 130 Cytokines in the Regulation of Adipocyte Biological Function.Inflammation. 2019 Jun;42(3):790-798. doi: 10.1007/s10753-019-00959-6.
184 Long non-coding RNA metallothionein 1 pseudogene 3 promotes p2y12 expression by sponging miR-126 to activate platelet in diabetic animal model.Platelets. 2019;30(4):452-459. doi: 10.1080/09537104.2018.1457781. Epub 2018 Apr 4.
185 Inhibiting Insulin-Mediated 2-Adrenergic Receptor Activation Prevents Diabetes-Associated Cardiac Dysfunction.Circulation. 2017 Jan 3;135(1):73-88. doi: 10.1161/CIRCULATIONAHA.116.022281. Epub 2016 Nov 4.
186 Associations of common variants in methionine metabolism pathway genes with plasma homocysteine and the risk of type 2 diabetes in Han Chinese.J Nutrigenet Nutrigenomics. 2014;7(2):63-74. doi: 10.1159/000365007. Epub 2014 Jul 25.
187 A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians.Hum Mol Genet. 2015 May 15;24(10):2985-96. doi: 10.1093/hmg/ddv040. Epub 2015 Feb 6.
188 Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations.Mol Nutr Food Res. 2005 Oct;49(10):972-6. doi: 10.1002/mnfr.200500087.
189 Long-term Prediction of Cardiovascular Outcomes by Circulating CD34+ and CD34+CD133+ Stem Cells in Patients With Type 2 Diabetes.Diabetes Care. 2017 Jan;40(1):125-131. doi: 10.2337/dc16-1755. Epub 2016 Nov 4.
190 Influence of a type 2 diabetes associated prostaglandin E synthase 2 polymorphism on blood prostaglandin E2 levels.Prostaglandins Leukot Essent Fatty Acids. 2009 Apr;80(4):185-8. doi: 10.1016/j.plefa.2009.02.001. Epub 2009 Mar 5.
191 Protein Tyrosine Phosphatase, Receptor Type B (PTPRB) Inhibits Brown Adipocyte Differentiation through Regulation of VEGFR2 Phosphorylation.J Microbiol Biotechnol. 2019 Apr 28;29(4):645-650. doi: 10.4014/jmb.1810.10033.
192 Genetic variation in receptor protein tyrosine phosphatase sigma is associated with type 2 diabetes in Swedish Caucasians.Eur J Endocrinol. 2007 Oct;157(4):459-64. doi: 10.1530/EJE-07-0114.
193 Urinary equol, but not daidzein and genistein, was inversely associated with the risk of type 2 diabetes in Chinese adults.Eur J Nutr. 2020 Mar;59(2):719-728. doi: 10.1007/s00394-019-01939-0. Epub 2019 Apr 5.
194 Identification of haplotype tag single nucleotide polymorphisms within the nuclear factor-B family genes and their clinical relevance in patients with major trauma.Crit Care. 2015 Mar 20;19(1):95. doi: 10.1186/s13054-015-0836-6.
195 Convergence of innate immunity and insulin resistance as evidenced by increased nucleotide oligomerization domain (NOD) expression and signaling in monocytes from patients with type 2 diabetes.Cytokine. 2013 Nov;64(2):564-70. doi: 10.1016/j.cyto.2013.08.003. Epub 2013 Sep 6.
196 Enhanced VEGF signalling mediates cerebral neovascularisation via downregulation of guidance protein ROBO4 in a rat model of diabetes.Diabetologia. 2017 Apr;60(4):740-750. doi: 10.1007/s00125-017-4214-6. Epub 2017 Jan 23.
197 Galectin-3 and S100A9: Novel Diabetogenic Factors Mediating Pancreatic Cancer-Associated Diabetes.Diabetes Care. 2019 Sep;42(9):1752-1759. doi: 10.2337/dc19-0217. Epub 2019 Jul 1.
198 Association of SelS mRNA expression in omental adipose tissue with Homa-IR and serum amyloid A in patients with type 2 diabetes mellitus.Chin Med J (Engl). 2008 Jul 5;121(13):1165-8.
199 Adverse epigenetic signatures by histone methyltransferase Set7 contribute to vascular dysfunction in patients with type 2 diabetes mellitus.Circ Cardiovasc Genet. 2015 Feb;8(1):150-8. doi: 10.1161/CIRCGENETICS.114.000671. Epub 2014 Dec 3.
200 Serum Surfactant Protein D as a Biomarker for Measuring Lung Involvement in Obese Patients With Type 2 Diabetes.J Clin Endocrinol Metab. 2017 Nov 1;102(11):4109-4116. doi: 10.1210/jc.2017-00913.
201 SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice.EBioMedicine. 2018 Oct;36:347-357. doi: 10.1016/j.ebiom.2018.09.037. Epub 2018 Sep 29.
202 Arg913Gln variation of SLC12A3 gene is associated with diabetic nephropathy in type 2 diabetes and Gitelman syndrome: a systematic review.BMC Nephrol. 2019 Oct 28;20(1):393. doi: 10.1186/s12882-019-1590-9.
203 Predictive Factors for Efficacy of AST-120 Treatment in Diabetic Nephropathy: a Prospective Single-Arm, Open-Label, Multi-Center Study.J Korean Med Sci. 2019 Apr 22;34(15):e117. doi: 10.3346/jkms.2019.34.e117.
204 Decreased VMAT2 in the pancreas of humans with type 2 diabetes mellitus measured in vivo by PET imaging.Diabetologia. 2018 Dec;61(12):2598-2607. doi: 10.1007/s00125-018-4624-0. Epub 2018 May 2.
205 Toll-like receptor 4 and inducible nitric oxide synthase gene polymorphisms are associated with Type 2 diabetes.J Diabetes Complications. 2010 May-Jun;24(3):192-8. doi: 10.1016/j.jdiacomp.2009.03.003. Epub 2009 Apr 23.
206 Common variants related to serum uric acid concentrations are associated with glucose metabolism and insulin secretion in a Chinese population.PLoS One. 2015 Jan 24;10(1):e0116714. doi: 10.1371/journal.pone.0116714. eCollection 2015.
207 Discovery of novel 5-oxa-2,6-diazaspiro[3.4]oct-6-ene derivatives as potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonists for treatment of type 2 diabetes mellitus.Bioorg Med Chem. 2017 Aug 1;25(15):4175-4193. doi: 10.1016/j.bmc.2017.06.007. Epub 2017 Jun 9.
208 Transporters in Drug Development: Scientific and Regulatory Considerations.Clin Pharmacol Ther. 2018 Nov;104(5):793-796. doi: 10.1002/cpt.1214. Epub 2018 Sep 30.
209 Effects of Sodium and Amino Acid Substrate Availability upon the Expression and Stability of the SNAT2 (SLC38A2) Amino Acid Transporter.Front Pharmacol. 2018 Feb 7;9:63. doi: 10.3389/fphar.2018.00063. eCollection 2018.
210 Multipolar pacing by cardiac resynchronization therapy with a defibrillators treatment in type 2 diabetes mellitus failing heart patients: impact on responders rate, and clinical outcomes.Cardiovasc Diabetol. 2017 Jun 9;16(1):75. doi: 10.1186/s12933-017-0554-2.
211 Arrhythmogenic gene remodelling in elderly patients with type 2 diabetes with aortic stenosis and normal left ventricular ejection fraction.Exp Physiol. 2017 Nov 1;102(11):1424-1434. doi: 10.1113/EP086412. Epub 2017 Sep 24.
212 Individualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data.Mol Diagn Ther. 2012 Oct;16(5):285-302. doi: 10.1007/s40291-012-0002-7.
213 Influence of the SLCO1B3 Gene on Sulfonylurea Failure in Patients with Type 2 Diabetes in China.Exp Clin Endocrinol Diabetes. 2017 Jul;125(7):449-453. doi: 10.1055/s-0043-103968. Epub 2017 Apr 25.
214 A comparison of gene expression profiles in patients with coronary artery disease, type 2 diabetes, and their coexisting conditions.Diagn Pathol. 2017 Jun 8;12(1):44. doi: 10.1186/s13000-017-0630-7.
215 Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes.Nat Commun. 2017 Jun 6;8:15652. doi: 10.1038/ncomms15652.
216 The Mitochondrial Antioxidant SS-31 Modulates Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy in Type 2 Diabetes.J Clin Med. 2019 Aug 28;8(9):1322. doi: 10.3390/jcm8091322.
217 Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver.Free Radic Biol Med. 2009 Aug 1;47(3):219-28. doi: 10.1016/j.freeradbiomed.2009.01.028. Epub 2009 Feb 20.
218 Androgenic correlates of genetic variation in the gene encoding 5alpha-reductase type 1.J Hum Genet. 2005;50(10):534-537. doi: 10.1007/s10038-005-0289-x. Epub 2005 Sep 10.
219 Design and synthesis of a novel series of orally active, selective somatostatin receptor 2 agonists for the treatment of type 2 diabetes.Bioorg Med Chem. 2017 Nov 1;25(21):5995-6006. doi: 10.1016/j.bmc.2017.09.031. Epub 2017 Sep 21.
220 SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes.Diabetologia. 2017 Jul;60(7):1304-1313. doi: 10.1007/s00125-017-4261-z. Epub 2017 Apr 5.
221 Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans.PLoS One. 2014 Mar 3;9(3):e86931. doi: 10.1371/journal.pone.0086931. eCollection 2014.
222 PDE5 Inhibition Stimulates Tie2-Expressing Monocytes and Angiopoietin-1 Restoring Angiogenic Homeostasis in Diabetes.J Clin Endocrinol Metab. 2019 Jul 1;104(7):2623-2636. doi: 10.1210/jc.2018-02525.
223 Genetic variants of 11 telomere-pathway gene loci and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study.Atherosclerosis. 2011 Sep;218(1):144-6. doi: 10.1016/j.atherosclerosis.2011.05.013. Epub 2011 May 18.
224 Combined creatinine-cystatin C CKD-EPI equation significantly underestimates measured glomerular filtration rate in people with type 2 diabetes mellitus.Clin Biochem. 2018 Mar;53:43-48. doi: 10.1016/j.clinbiochem.2018.01.005. Epub 2018 Jan 10.
225 ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response.Nat Commun. 2019 Jul 19;10(1):3195. doi: 10.1038/s41467-019-10967-7.
226 Landscape of the relationship between type 2 diabetes and coronary heart disease through an integrated gene network analysis.Gene. 2014 Apr 10;539(1):30-6. doi: 10.1016/j.gene.2014.02.001. Epub 2014 Feb 5.
227 A nonsense polymorphism (R392X) in TLR5 protects from obesity but predisposes to diabetes.J Immunol. 2013 Apr 1;190(7):3716-20. doi: 10.4049/jimmunol.1202936. Epub 2013 Mar 1.
228 Glipizide suppresses prostate cancer progression in the TRAMP model by inhibiting angiogenesis.Sci Rep. 2016 Jun 13;6:27819. doi: 10.1038/srep27819.
229 Sodium-glucose cotransporter 2 inhibitor-induced changes in body composition and simultaneous changes in metabolic profile: 52-week prospective LIGHT (Luseogliflozin: the Components of Weight Loss in Japanese Patients with Type 2 Diabetes Mellitus) Study.J Diabetes Investig. 2019 Jan;10(1):108-117. doi: 10.1111/jdi.12851. Epub 2018 May 16.
230 Genetic variations underlying Alzheimer's disease: evidence from genome-wide association studies and beyond.Lancet Neurol. 2016 Jul;15(8):857-868. doi: 10.1016/S1474-4422(16)00127-7.
231 Gene variation of the transient receptor potential cation channel, subfamily M, member 2 (TRPM2) and type 2 diabetes mellitus: A case-control study.Clin Chim Acta. 2010 Oct 9;411(19-20):1437-40. doi: 10.1016/j.cca.2010.05.036. Epub 2010 Jun 1.
232 Effect of glibenclamide on the prevention of secondary brain injury following ischemic stroke in humans.Neurosurg Focus. 2014 Jan;36(1):E11. doi: 10.3171/2013.10.FOCUS13404.
233 Reduction of glycosphingolipid biosynthesis stimulates biliary lipid secretion in mice.Hepatology. 2009 Feb;49(2):637-45. doi: 10.1002/hep.22663.
234 Ubiquitin-specific protease 2-69 in macrophages potentially modulates metainflammation.FASEB J. 2013 Dec;27(12):4940-53. doi: 10.1096/fj.13-233528. Epub 2013 Sep 4.
235 Comparative understanding of UTS2 and UTS2R genes for their involvement in type 2 diabetes mellitus.Int J Biol Sci. 2008 Apr 23;4(2):96-102. doi: 10.7150/ijbs.4.96.
236 Plasma vascular endothelial growth factor B levels are increased in patients with newly diagnosed type 2 diabetes mellitus and associated with the first phase of glucose-stimulated insulin secretion function of -cell.J Endocrinol Invest. 2017 Nov;40(11):1219-1226. doi: 10.1007/s40618-017-0677-z. Epub 2017 May 18.
237 Association of VKORC1 -1639 G>A polymorphism with carotid intima-media thickness in type 2 diabetes mellitus.Diabetes Res Clin Pract. 2011 Nov;94(2):236-41. doi: 10.1016/j.diabres.2011.06.021. Epub 2011 Jul 20.
238 Impaired osteogenic differentiation and enhanced cellular receptor of advanced glycation end products sensitivity in patients with type 2 diabetes.J Bone Miner Metab. 2017 Nov;35(6):631-641. doi: 10.1007/s00774-016-0800-9. Epub 2016 Nov 21.
239 Trend over time in hepatic fibrosis score in a cohort of type 2 diabetes patients.Diabetes Res Clin Pract. 2018 Jan;135:65-72. doi: 10.1016/j.diabres.2017.10.023. Epub 2017 Oct 31.
240 TNF-alpha -308G/A and -238G/A polymorphisms and its protein network associated with type 2 diabetes mellitus.Saudi J Biol Sci. 2017 Sep;24(6):1195-1203. doi: 10.1016/j.sjbs.2016.05.012. Epub 2016 May 25.
241 Vitamin D Switches BAF Complexes to Protect Cells.Cell. 2018 May 17;173(5):1135-1149.e15. doi: 10.1016/j.cell.2018.04.013. Epub 2018 May 10.
242 DGK deficiency protects against peripheral insulin resistance and improves energy metabolism.J Lipid Res. 2017 Dec;58(12):2324-2333. doi: 10.1194/jlr.M079723. Epub 2017 Oct 24.
243 Circulating bone morphogenetic protein-9 in relation to metabolic syndrome and insulin resistance.Sci Rep. 2017 Dec 13;7(1):17529. doi: 10.1038/s41598-017-17807-y.
244 Inhibition of protein tyrosine phosphatases unmasks vasoconstriction and potentiates calcium signaling in rat aorta smooth muscle cells in response to an agonist of 5-HT2B receptors BW723C86.Biochem Biophys Res Commun. 2017 Jan 29;483(1):700-705. doi: 10.1016/j.bbrc.2016.12.079. Epub 2016 Dec 13.
245 The renal tubular damage marker urinary N-acetyl--D-glucosaminidase may be more closely associated with early detection of atherosclerosis than the glomerular damage marker albuminuria in patients with type 2 diabetes.Cardiovasc Diabetol. 2017 Jan 26;16(1):16. doi: 10.1186/s12933-017-0497-7.
246 Interactions of TRAF6 and NLRX1 gene polymorphisms with environmental factors on the susceptibility of type 2 diabetes mellitus vascular complications in a southern Han Chinese population.J Diabetes Complications. 2017 Dec;31(12):1652-1657. doi: 10.1016/j.jdiacomp.2017.08.013. Epub 2017 Sep 1.
247 Plasma lecithin:cholesterol acyltransferase and phospholipid transfer protein activity independently associate with nonalcoholic fatty liver disease.Eur J Clin Invest. 2018 Sep;48(9):e12988. doi: 10.1111/eci.12988. Epub 2018 Jul 13.
248 Nightshift work, chronotype, and genome-wide DNA methylation in blood.Epigenetics. 2017;12(10):833-840. doi: 10.1080/15592294.2017.1366407. Epub 2017 Nov 27.
249 High intake of dietary advanced glycation end-products is associated with increased arterial stiffness and inflammation in subjects with type 2 diabetes.Nutr Metab Cardiovasc Dis. 2017 Nov;27(11):978-984. doi: 10.1016/j.numecd.2017.06.014. Epub 2017 Jul 8.
250 Blockade of sigma 1 receptors alleviates sensory signs of diabetic neuropathy in rats.Eur J Pain. 2017 Jan;21(1):61-72. doi: 10.1002/ejp.897. Epub 2016 Jun 24.
251 Expression of the ZIP/SLC39A transporters in -cells: a systematic review and integration of multiple datasets.BMC Genomics. 2017 Sep 11;18(1):719. doi: 10.1186/s12864-017-4119-2.
252 Hepcidin, soluble transferrin receptor and IL-6 levels in obese children and adolescents with and without type 2 diabetes mellitus/impaired glucose tolerance and their association with obstructive sleep apnea.J Endocrinol Invest. 2018 Aug;41(8):969-975. doi: 10.1007/s40618-017-0823-7. Epub 2018 Jan 5.
253 Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI.Transl Psychiatry. 2019 Nov 21;9(1):315. doi: 10.1038/s41398-019-0652-x.
254 The effect of apelin-13 on pancreatic islet beta cell mass and myocardial fatty acid and glucose metabolism of experimental type 2 diabetic rats.Peptides. 2019 Apr;114:1-7. doi: 10.1016/j.peptides.2019.03.006. Epub 2019 Apr 4.
255 Increased AQP7 abundance in skeletal muscle from obese men with type 2 diabetes.Am J Physiol Endocrinol Metab. 2018 Sep 1;315(3):E367-E373. doi: 10.1152/ajpendo.00468.2017. Epub 2018 May 21.
256 Effects of Coenzyme Q10 Supplementation on Serum Values of Gamma-glutamyl transferase, Pseudocholinesterase, Bilirubin, Ferritin, and High-Sensitivity C-Reactive Protein in Women with Type 2 Diabetes.Exp Clin Endocrinol Diabetes. 2019 May;127(5):311-319. doi: 10.1055/s-0043-124183. Epub 2018 Jan 24.
257 Advances in oral peptide therapeutics.Nat Rev Drug Discov. 2020 Apr;19(4):277-289. doi: 10.1038/s41573-019-0053-0. Epub 2019 Dec 17.
258 Exome sequencing of 20,791cases of type 2 diabetes and 24,440controls.Nature. 2019 Jun;570(7759):71-76. doi: 10.1038/s41586-019-1231-2. Epub 2019 May 22.
259 Clcn3 deficiency ameliorates high-fat diet-induced obesity and adipose tissue macrophage inflammation in mice.Acta Pharmacol Sin. 2019 Dec;40(12):1532-1543. doi: 10.1038/s41401-019-0229-5. Epub 2019 Jun 5.
260 Use of 4-Hydroxycholesterol Plasma Concentrations as an Endogenous Biomarker of CYP3A Activity: Clinical Validation in Individuals With Type 2 Diabetes.Clin Pharmacol Ther. 2019 Oct;106(4):831-840. doi: 10.1002/cpt.1472. Epub 2019 Jun 5.
261 Lipid Levels Related to Osteoporosis in Patients with Type 2 Diabetes.Exp Clin Endocrinol Diabetes. 2019 Jul;127(7):468-472. doi: 10.1055/a-0735-9361. Epub 2018 Sep 20.
262 Association of EPHX2 R287Q Polymorphism with Diabetic Nephropathy in Chinese Type 2 Diabetic Patients.J Diabetes Res. 2018 Feb 5;2018:2786470. doi: 10.1155/2018/2786470. eCollection 2018.
263 Pharmacological PAR-1 inhibition reduces blood glucose levels but does not improve kidney function in experimental type 2 diabetic nephropathy.FASEB J. 2019 Oct;33(10):10966-10972. doi: 10.1096/fj.201900516R. Epub 2019 Jul 9.
264 Expression of growth-associated protein 43 in the skin nerve fibers of patients with type 2 diabetes mellitus.J Neurol Sci. 2012 Apr 15;315(1-2):60-3. doi: 10.1016/j.jns.2011.11.038. Epub 2011 Dec 29.
265 Leveraging Genetics to Improve Cardiovascular Health in Diabetes: The 2018 Edwin Bierman Award Lecture.Diabetes. 2019 Mar;68(3):479-489. doi: 10.2337/dbi18-0036.
266 Discovery and biological evaluation of novel G protein-coupled receptor 119 agonists for type 2 diabetes.Arch Pharm (Weinheim). 2019 Apr;352(4):e1800267. doi: 10.1002/ardp.201800267. Epub 2019 Feb 10.
267 The complement receptor C5aR2 promotes protein kinase R expression and contributes to NLRP3 inflammasome activation and HMGB1 release from macrophages.J Biol Chem. 2019 May 24;294(21):8384-8394. doi: 10.1074/jbc.RA118.006508. Epub 2019 Apr 10.
268 Genetic Assessment of Potential Long-Term On-Target Side Effects of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibitors.Circ Genom Precis Med. 2019 Jan;12(1):e002196. doi: 10.1161/CIRCGEN.118.002196.
269 Validation of a protein biomarker test for predicting renal decline in type 2 diabetes: The Fremantle Diabetes Study Phase II.J Diabetes Complications. 2019 Dec;33(12):107406. doi: 10.1016/j.jdiacomp.2019.07.003. Epub 2019 Aug 27.
270 IL-22 produced by type 3 innate lymphoid cells (ILC3s) reduces the mortality of type 2 diabetes mellitus (T2DM) mice infected with Mycobacterium tuberculosis.PLoS Pathog. 2019 Dec 6;15(12):e1008140. doi: 10.1371/journal.ppat.1008140. eCollection 2019 Dec.
271 A systematic review on the functional role of Th1/Th2 cytokines in type 2 diabetes and related metabolic complications.Cytokine. 2020 Feb;126:154892. doi: 10.1016/j.cyto.2019.154892. Epub 2019 Nov 6.
272 Cholesterol-Lowering Gene Therapy Prevents Heart Failure with Preserved Ejection Fraction in Obese Type 2 Diabetic Mice.Int J Mol Sci. 2019 May 6;20(9):2222. doi: 10.3390/ijms20092222.
273 mtDNA Haplogroup N9a Increases the Risk of Type 2 Diabetes by Altering Mitochondrial Function and Intracellular Mitochondrial Signals.Diabetes. 2018 Jul;67(7):1441-1453. doi: 10.2337/db17-0974. Epub 2018 May 7.
274 MAPK Erk5 in Leptin ReceptorExpressing Neurons Controls Body Weight and Systemic Energy Homeostasis in Female Mice.Endocrinology. 2019 Dec 1;160(12):2837-2848. doi: 10.1210/en.2019-00090.
275 Neprilysin inhibition: a new therapeutic option for type 2 diabetes?.Diabetologia. 2019 Jul;62(7):1113-1122. doi: 10.1007/s00125-019-4889-y. Epub 2019 May 14.
276 Association Between Matrix Metalloproteinase-3 Activity and Glomerular Filtration Rate and Albuminuria Status in Patients With Type 2 Diabetes Mellitus.Iran J Kidney Dis. 2018 Jan;12(1):40-47.
277 Clinically feasible method for assessing leukocyte rheology in whole blood.Heart Vessels. 2020 Feb;35(2):268-277. doi: 10.1007/s00380-019-01486-y. Epub 2019 Aug 23.
278 Polymorphism of Secretary PLA2G2A Gene Associated with Its Serum Level in Type2 Diabetes Mellitus Patients in Northern Iran.Endocr Metab Immune Disord Drug Targets. 2019;19(8):1192-1197. doi: 10.2174/1871530319666190528111225.
279 Assessment of two novel renal tubular proteins in type 2 diabetic patients with nephropathy.J Investig Med. 2020 Mar;68(3):748-755. doi: 10.1136/jim-2019-001135. Epub 2019 Nov 12.
280 Lower sarcoplasmic reticulum Ca(2+) threshold for triggering afterdepolarizations in diabetic rat hearts.Heart Rhythm. 2019 May;16(5):765-772. doi: 10.1016/j.hrthm.2018.11.001. Epub 2018 Nov 7.
281 Effect of Irbesartan on AGEs-RAGE and MMPs systems in rat type 2 diabetes myocardial-fibrosis model.Exp Biol Med (Maywood). 2019 May;244(7):612-620. doi: 10.1177/1535370219840981. Epub 2019 Apr 26.
282 Secreted Wnt6 mediates diabetes-associated centrosome amplification via its receptor FZD4.Am J Physiol Cell Physiol. 2020 Jan 1;318(1):C48-C62. doi: 10.1152/ajpcell.00091.2019. Epub 2019 Oct 16.
283 The heparan sulfate proteoglycan gene polymorphism: association with type 2 diabetic nephropathy in Chinese.Mol Cell Biochem. 2003 Mar;245(1-2):121-6. doi: 10.1023/a:1022870128494.
284 Co-Expression Networks Reveal Potential Regulatory Roles of miRNAs in Fatty Acid Composition of Nelore Cattle.Front Genet. 2019 Jul 11;10:651. doi: 10.3389/fgene.2019.00651. eCollection 2019.
285 Evaluation of the rs3088442 G>A SLC22A3 Gene Polymorphism and the Role of microRNA 147 in Groups of Adult Pakistani Populations With Type 2 Diabetes in Response to Metformin.Can J Diabetes. 2019 Mar;43(2):128-135.e3. doi: 10.1016/j.jcjd.2018.07.001. Epub 2018 Jul 17.
286 CYP2C8 and SLCO1B1 Variants and Therapeutic Response to Thiazolidinediones in Patients With Type 2 Diabetes. Diabetes Care. 2016 Nov;39(11):1902-1908.
287 A Novel Role for Somatostatin in the Survival of Mouse Pancreatic Beta Cells.Cell Physiol Biochem. 2019;52(3):486-502. doi: 10.33594/000000035. Epub 2019 Mar 15.
288 Associations of urinary, glomerular, and tubular markers with the development of diabetic kidney disease in type 2 diabetes patients.J Clin Lab Anal. 2018 Jan;32(1):e22191. doi: 10.1002/jcla.22191. Epub 2017 Feb 25.
289 Type 2 diabetes-associated polymorphisms correlate with SIRT1 and TGF-1 gene expression.Ann Hum Genet. 2020 Mar;84(2):185-194. doi: 10.1111/ahg.12363. Epub 2019 Dec 4.
290 Thioredoxin, thioredoxin interacting protein and transducer and activator of transcription 3 in gestational diabetes.Mol Biol Rep. 2020 Feb;47(2):1199-1206. doi: 10.1007/s11033-019-05221-8. Epub 2019 Dec 17.
291 VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy.Diabetes. 2019 Jan;68(1):172-187. doi: 10.2337/db18-0045. Epub 2018 Nov 2.
292 Decreased exposure of simvastatin and simvastatin acid in a rat model of type 2 diabetes.Acta Pharmacol Sin. 2014 Sep;35(9):1215-25. doi: 10.1038/aps.2014.39. Epub 2014 Aug 25.
293 A Pilot Study towards the Impact of Type 2 Diabetes on the Expression and Activities of Drug Metabolizing Enzymes and Transporters in Human Duodenum.Int J Mol Sci. 2019 Jul 2;20(13):3257. doi: 10.3390/ijms20133257.
294 Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis.JAMA. 2016 Oct 4;316(13):1383-1391. doi: 10.1001/jama.2016.14568.
295 /-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes.Cell Rep. 2016 Mar 29;14(12):2872-88. doi: 10.1016/j.celrep.2016.02.076. Epub 2016 Mar 17.
296 The association between lipid metabolism gene polymorphisms and nephropathy in type 2 diabetes: a meta-analysis.Int Urol Nephrol. 2015 Jan;47(1):117-30. doi: 10.1007/s11255-014-0843-6. Epub 2014 Sep 28.
297 A Dipeptidyl Peptidase-4 Inhibitor Suppresses Macrophage Foam Cell Formation in Diabetic db/db Mice and Type 2 Diabetes Patients.Int J Endocrinol. 2018 Dec 9;2018:8458304. doi: 10.1155/2018/8458304. eCollection 2018.
298 Synthesis of oxazolidinone from enantiomerically enriched allylic alcohols and determination of their molecular docking and biologic activities.Bioorg Chem. 2019 Jul;88:102980. doi: 10.1016/j.bioorg.2019.102980. Epub 2019 May 9.
299 Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex.Nature. 2018 Mar 1;555(7694):121-125. doi: 10.1038/nature25773. Epub 2018 Feb 21.
300 Identification of key genes involved in type 2 diabetic islet dysfunction: a bioinformatics study.Biosci Rep. 2019 May 31;39(5):BSR20182172. doi: 10.1042/BSR20182172. Print 2019 May 31.
301 Involvement of the Adhesion GPCRs Latrophilins in the Regulation of Insulin Release.Cell Rep. 2019 Feb 5;26(6):1573-1584.e5. doi: 10.1016/j.celrep.2019.01.040.
302 Prognostic value of plasma MR-proADM vs NT-proBNP for heart failure in people with type 2 diabetes: the SURDIAGENE prospective study.Diabetologia. 2018 Dec;61(12):2643-2653. doi: 10.1007/s00125-018-4727-7. Epub 2018 Sep 19.
303 Altered Expression of Adrenomedullin 2 and its Receptor in the Adipose Tissue of Obese Patients.J Clin Endocrinol Metab. 2020 Jan 1;105(1):dgz066. doi: 10.1210/clinem/dgz066.
304 Adenosine deaminase and body mass index in non-insulin-dependent diabetes mellitus.Metabolism. 1999 Aug;48(8):949-51. doi: 10.1016/s0026-0495(99)90187-7.
305 The elevated gene expression level of the A(2B) adenosine receptor is associated with hyperglycemia in women with gestational diabetes mellitus.Diabetes Metab Res Rev. 2014 Jan;30(1):42-53. doi: 10.1002/dmrr.2446.
306 Human-specific SNP in obesity genes, adrenergic receptor beta2 (ADRB2), Beta3 (ADRB3), and PPAR 2 (PPARG), during primate evolution.PLoS One. 2012;7(8):e43461. doi: 10.1371/journal.pone.0043461. Epub 2012 Aug 24.
307 Reduced expression of the KATP channel subunit, Kir6.2, is associated with decreased expression of neuropeptide Y and agouti-related protein in the hypothalami of Zucker diabetic fatty rats.J Neuroendocrinol. 2007 Dec;19(12):941-51. doi: 10.1111/j.1365-2826.2007.01607.x.
308 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.Nat Commun. 2018 Jan 22;9(1):321. doi: 10.1038/s41467-017-02380-9.
309 Type-2 diabetic aldehyde dehydrogenase 2 mutant mice (ALDH 2*2) exhibiting heart failure with preserved ejection fraction phenotype can be determined by exercise stress echocardiography.PLoS One. 2018 Apr 20;13(4):e0195796. doi: 10.1371/journal.pone.0195796. eCollection 2018.
310 A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity.Ophthalmic Genet. 2019 Jun;40(3):252-258. doi: 10.1080/13816810.2019.1633549. Epub 2019 Jul 2.
311 Role of the 12-lipoxygenase pathway in diabetes pathogenesis and complications.Pharmacol Ther. 2019 Mar;195:100-110. doi: 10.1016/j.pharmthera.2018.10.010. Epub 2018 Oct 19.
312 Assessment of association between lipoxygenase genes variants in elderly Greek population and type 2 diabetes mellitus.Diab Vasc Dis Res. 2018 Jul;15(4):340-343. doi: 10.1177/1479164118756241. Epub 2018 Feb 2.
313 Magnificamide, a -Defensin-Like Peptide from the Mucus of the Sea Anemone Heteractis magnifica, Is a Strong Inhibitor of Mammalian -Amylases.Mar Drugs. 2019 Sep 21;17(10):542. doi: 10.3390/md17100542.
314 Angiotensin-(1-7), Adipokines and Inflammation.Metabolism. 2019 Jun;95:36-45. doi: 10.1016/j.metabol.2019.03.006. Epub 2019 Mar 21.
315 Effects of Angiopoietin-Like 3 on Triglyceride Regulation, Glucose Homeostasis, and Diabetes.Dis Markers. 2019 Mar 3;2019:6578327. doi: 10.1155/2019/6578327. eCollection 2019.
316 The Effects of Adiponectin and Adiponectin Receptor 1 Levels on Macrovascular Complications Among Patients with Type 2 Diabetes Mellitus.Cell Physiol Biochem. 2019;52(2):225-231. doi: 10.33594/000000016. Epub 2019 Feb 28.
317 Association between plasma activities of semicarbazide-sensitive amine oxidase and angiotensin-converting enzyme in patients with type 1 diabetes mellitus.Diabetologia. 2005 May;48(5):1002-7. doi: 10.1007/s00125-005-1716-4. Epub 2005 Apr 14.
318 Promoting effects of the adipokine, apelin, on diabetic nephropathy.PLoS One. 2013;8(4):e60457. doi: 10.1371/journal.pone.0060457. Epub 2013 Apr 5.
319 Biliopancreatic Diversion Decreases Postprandial Apolipoprotein A-IV Levels in Mildly Obese Individuals with Type 2 Diabetes Mellitus: a Prospective Study.Obes Surg. 2017 Apr;27(4):1008-1012. doi: 10.1007/s11695-016-2414-7.
320 A higher glycemic response to oral glucose is associated with higher plasma apolipoprotein C3 independently of BMI in healthy twins.Nutr Metab Cardiovasc Dis. 2020 Mar 9;30(3):459-466. doi: 10.1016/j.numecd.2019.10.005. Epub 2019 Oct 15.
321 Elevation of serum oxLDL/2-GPI complexes was correlated with diabetic microvascular complications in Type 2 diabetes mellitus patients.J Clin Lab Anal. 2019 Feb;33(2):e22676. doi: 10.1002/jcla.22676. Epub 2018 Sep 26.
322 Circulating Apolipoprotein L1 is associated with insulin resistance-induced abnormal lipid metabolism.Sci Rep. 2019 Oct 16;9(1):14869. doi: 10.1038/s41598-019-51367-7.
323 Combined vildagliptin and memantine treatment downregulates expression of amyloid precursor protein, and total and phosphorylated tau in a rat model of combined Alzheimer's disease and type 2 diabetes.Naunyn Schmiedebergs Arch Pharmacol. 2019 Jun;392(6):685-695. doi: 10.1007/s00210-019-01616-3. Epub 2019 Feb 13.
324 Gene expression of paired abdominal adipose AQP7 and liver AQP9 in patients with morbid obesity: relationship with glucose abnormalities.Metabolism. 2009 Dec;58(12):1762-8. doi: 10.1016/j.metabol.2009.06.004. Epub 2009 Jul 16.
325 Emerging role of testosterone in pancreatic -cell function and insulin secretion.J Endocrinol. 2019 Jan 1:JOE-18-0573.R1. doi: 10.1530/JOE-18-0573. Online ahead of print.
326 -arrestin-2 is involved in irisin induced glucose metabolism in type 2 diabetes via p38 MAPK signaling.Exp Cell Res. 2017 Nov 15;360(2):199-204. doi: 10.1016/j.yexcr.2017.09.006. Epub 2017 Sep 6.
327 Arylsulphatase A Pseudodeficiency (ARSA-PD), hypertension and chronic renal disease in Aboriginal Australians.Sci Rep. 2018 Jul 19;8(1):10912. doi: 10.1038/s41598-018-29279-9.
328 Activating transcription factor 3 is a target molecule linking hepatic steatosis to impaired glucose homeostasis. J Hepatol. 2017 Aug;67(2):349-359.
329 Dysregulated autophagy in muscle precursor cells from humans with type 2 diabetes.Sci Rep. 2019 Jun 3;9(1):8169. doi: 10.1038/s41598-019-44535-2.
330 Insulin degrading enzyme contributes to the pathology in a mixed model of Type 2 diabetes and Alzheimer's disease: possible mechanisms of IDE in T2D and AD.Biosci Rep. 2018 Jan 10;38(1):BSR20170862. doi: 10.1042/BSR20170862. Print 2018 Feb 28.
331 Association of cardiac injury with iron-increased oxidative and nitrative modifications of the SERCA2a isoform of sarcoplasmic reticulum Ca(2+)-ATPase in diabetic rats.Biochimie. 2016 Aug;127:144-52. doi: 10.1016/j.biochi.2016.05.011. Epub 2016 May 21.
332 First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes.Diabetes Care. 2018 Nov;41(11):2396-2403. doi: 10.2337/dc18-1032. Epub 2018 Sep 25.
333 Antagonism of vasopressin V2 receptor improves albuminuria at the early stage of diabetic nephropathy in a mouse model of type 2 diabetes.J Diabetes Complications. 2017 Jun;31(6):929-932. doi: 10.1016/j.jdiacomp.2017.04.005. Epub 2017 Apr 6.
334 Circulating zinc-2-glycoprotein levels are low in newly diagnosed patients with metabolic syndrome and correlate with adiponectin.Nutr Metab (Lond). 2017 Aug 14;14:53. doi: 10.1186/s12986-017-0210-6. eCollection 2017.
335 Association between 24-h urine sodium and proteinuria among hospitalized patients with type 2 diabetes.J Diabetes Complications. 2020 Mar;34(3):107498. doi: 10.1016/j.jdiacomp.2019.107498. Epub 2019 Nov 29.
336 BACE2 suppression promotes -cell survival and function in a model of type 2 diabetes induced by human islet amyloid polypeptide overexpression.Cell Mol Life Sci. 2017 Aug;74(15):2827-2838. doi: 10.1007/s00018-017-2505-1. Epub 2017 Mar 23.
337 BCL11A: a potential diagnostic biomarker and therapeutic target in human diseases.Biosci Rep. 2019 Nov 29;39(11):BSR20190604. doi: 10.1042/BSR20190604.
338 Nesfatin-1 ameliorates type-2 diabetes-associated reproductive dysfunction in male mice.J Endocrinol Invest. 2020 Apr;43(4):515-528. doi: 10.1007/s40618-019-01136-0. Epub 2019 Nov 5.
339 Association of Brain-Derived Neurotrophic Factor With Cognitive Function: An Investigation of Sex Differences in Patients With Type 2 Diabetes.Psychosom Med. 2019 Jul/Aug;81(6):488-494. doi: 10.1097/PSY.0000000000000709.
340 Reassessment of the putative role of BLK-p.A71T loss-of-function mutation in MODY and type 2 diabetes.Diabetologia. 2013 Mar;56(3):492-6. doi: 10.1007/s00125-012-2794-8. Epub 2012 Dec 6.
341 BMP7 improves insulin signal transduction in the liver via inhibition of mitogen-activated protein kinases.J Endocrinol. 2019 Nov;243(2):97-110. doi: 10.1530/JOE-18-0693.
342 Serum complement C3 and islet -cell function in patients with type 2 diabetes: A 4.6-year prospective follow-up study.Endocrine. 2020 Feb;67(2):321-330. doi: 10.1007/s12020-019-02144-z. Epub 2019 Nov 30.
343 Understanding the Role and Mechanism of Carbonic Anhydrase V in Obesity and its Therapeutic Implications.Curr Protein Pept Sci. 2018;19(9):909-923. doi: 10.2174/1389203718666170810145436.
344 Single-cell gene expression analysis reveals -cell dysfunction and deficit mechanisms in type 2 diabetes.BMC Bioinformatics. 2018 Dec 31;19(Suppl 19):515. doi: 10.1186/s12859-018-2519-1.
345 Analysis of Inflammatory Gene Expression Profile of Peripheral Blood Leukocytes in Type 2 Diabetes.Immunol Invest. 2019 Aug;48(6):618-631. doi: 10.1080/08820139.2019.1586917. Epub 2019 Apr 8.
346 The hyperglycemia stimulated myocardial endoplasmic reticulum (ER) stress contributes to diabetic cardiomyopathy in the transgenic non-obese type 2 diabetic rats: a differential role of unfolded protein response (UPR) signaling proteins.Int J Biochem Cell Biol. 2013 Feb;45(2):438-47. doi: 10.1016/j.biocel.2012.09.017. Epub 2012 Sep 29.
347 Hyperphagia and obesity in OLETF rats lacking CCK-1 receptors.Philos Trans R Soc Lond B Biol Sci. 2006 Jul 29;361(1471):1211-8. doi: 10.1098/rstb.2006.1857.
348 Genetic, pharmacological and functional analysis of cholecystokinin-1 and cholecystokinin-2 receptor polymorphism in type 2 diabetes and obese patients.Pharmacogenetics. 2002 Jan;12(1):23-30. doi: 10.1097/00008571-200201000-00004.
349 Dimethylguanidino Valerate: A Lifestyle-Related Metabolite Associated With Future Coronary Artery Disease and Cardiovascular Mortality.J Am Heart Assoc. 2019 Oct;8(19):e012846. doi: 10.1161/JAHA.119.012846. Epub 2019 Sep 19.
350 5-Lipoxygenase (ALOX5): Genetic susceptibility to type 2 diabetes and vitamin D effects on monocytes.J Steroid Biochem Mol Biol. 2019 Mar;187:52-57. doi: 10.1016/j.jsbmb.2018.10.022. Epub 2018 Dec 3.
351 Differential Expression of Human Peripheral Mononuclear Cells Phenotype Markers in Type 2 Diabetic Patients and Type 2 Diabetic Patients on Metformin.Front Endocrinol (Lausanne). 2018 Oct 9;9:537. doi: 10.3389/fendo.2018.00537. eCollection 2018.
352 Myeloid-derived suppressor cells suppress CD4+ T cell activity and prevent the development of type 2 diabetes.Acta Biochim Biophys Sin (Shanghai). 2018 Apr 1;50(4):362-369. doi: 10.1093/abbs/gmy014.
353 CD38 autoimmunity: recent advances and relevance to human diabetes.J Endocrinol Invest. 2004 Jul-Aug;27(7):695-707. doi: 10.1007/BF03347507.
354 No evidence of tachyphylaxis for insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) in subjects with type 2 diabetes, their first-degree relatives, or in healthy subjects.Peptides. 2020 Mar;125:170176. doi: 10.1016/j.peptides.2019.170176. Epub 2019 Oct 25.
355 Quantitative Systems Toxicology Analysis of In Vitro Mechanistic Assays Reveals Importance of Bile Acid Accumulation and Mitochondrial Dysfunction in TAK-875-Induced Liver Injury.Toxicol Sci. 2019 Feb 1;167(2):458-467. doi: 10.1093/toxsci/kfy253.
356 A type 2 diabetes-associated SNP in KCNQ1 (rs163184) modulates the binding activity of the locus for Sp3 and Lsd1/Kdm1a, potentially affecting CDKN1C expression.Int J Mol Med. 2018 Feb;41(2):717-728. doi: 10.3892/ijmm.2017.3273. Epub 2017 Nov 20.
357 Effects of Obstructive Sleep Apnea-Hypopnea Syndrome on Serum Carcinoembryonic Antigen Levels in Patients with Type 2 Diabetes Mellitus.Med Sci Monit. 2019 May 14;25:3558-3565. doi: 10.12659/MSM.913713.
358 Casein kinase 2 phosphorylates and stabilizes C/EBP in pancreatic cells.Biochem Biophys Res Commun. 2018 Feb 26;497(1):451-456. doi: 10.1016/j.bbrc.2018.02.108. Epub 2018 Feb 12.
359 A Carboxyl Ester Lipase (CEL) Mutant Causes Chronic Pancreatitis by Forming Intracellular Aggregates That Activate Apoptosis.J Biol Chem. 2016 Oct 28;291(44):23224-23236. doi: 10.1074/jbc.M116.734384. Epub 2016 Sep 20.
360 Nutritional markers in patients with diabetes and pancreatic exocrine failure.Acta Diabetol. 2019 Jun;56(6):651-658. doi: 10.1007/s00592-019-01294-w. Epub 2019 Feb 10.
361 Carboxylesterase Inhibitors: An Update.Curr Med Chem. 2018;25(14):1627-1649. doi: 10.2174/0929867325666171204155558.
362 Complement Factor B Is a Determinant of Both Metabolic and Cardiovascular Features of Metabolic Syndrome.Hypertension. 2017 Jul 24;70(3):624-33. doi: 10.1161/HYPERTENSIONAHA.117.09242. Online ahead of print.
363 Evaluation of chitotriosidase as a biomarker for adipose tissue inflammation in overweight individuals and type 2 diabetic patients.Int J Obes (Lond). 2019 Sep;43(9):1712-1723. doi: 10.1038/s41366-018-0225-8. Epub 2018 Oct 9.
364 Integrative Chinese herbal medicine therapy reduced the risk of type 2 diabetes mellitus in patients with polycystic ovary syndrome: A nationwide matched cohort study.J Ethnopharmacol. 2019 Oct 28;243:112091. doi: 10.1016/j.jep.2019.112091. Epub 2019 Jul 17.
365 MiR-126 Mediates Brain Endothelial Cell Exosome Treatment-Induced Neurorestorative Effects After Stroke in Type 2 Diabetes Mellitus Mice.Stroke. 2019 Oct;50(10):2865-2874. doi: 10.1161/STROKEAHA.119.025371. Epub 2019 Aug 9.
366 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.Nat Commun. 2018 Jul 27;9(1):2941. doi: 10.1038/s41467-018-04951-w.
367 The renin-angiotensin system as a target to solve the riddle of endocrine pancreas homeostasis.Biomed Pharmacother. 2019 Jan;109:639-645. doi: 10.1016/j.biopha.2018.10.191. Epub 2018 Nov 4.
368 Treatment of type 2 diabetes with the designer cytokine IC7Fc.Nature. 2019 Oct;574(7776):63-68. doi: 10.1038/s41586-019-1601-9. Epub 2019 Sep 25.
369 A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.PLoS One. 2011;6(7):e22353. doi: 10.1371/journal.pone.0022353. Epub 2011 Jul 22.
370 Effect of single nucleotide polymorphism in thrombin-activatable fibrinolysis inhibitor on the risk of diabetic macrovascular disease.Blood Coagul Fibrinolysis. 2015 Mar;26(2):185-90. doi: 10.1097/MBC.0000000000000216.
371 Regulatory mechanism of hypothalamo-pituitary-adrenal (HPA) axis and neuronal changes after adrenalectomy in type 2 diabetes.J Chem Neuroanat. 2010 Oct;40(2):130-9. doi: 10.1016/j.jchemneu.2010.05.003. Epub 2010 May 21.
372 MicroRNA-496 and Mechanistic Target of Rapamycin Expression are Associated with Type 2 Diabetes Mellitus and Obesity in Elderly People.Ann Nutr Metab. 2019;74(4):279-286. doi: 10.1159/000499576. Epub 2019 Apr 2.
373 Inhibiting hepatic gluconeogenesis by chitosan lactate nanoparticles containing CRTC2 siRNA targeted by poly(ethylene glycol)-glycyrrhetinic acid.Drug Deliv Transl Res. 2019 Jun;9(3):694-706. doi: 10.1007/s13346-019-00618-1.
374 Cardiotrophin-1 is a key regulator of glucose and lipid metabolism.Cell Metab. 2011 Aug 3;14(2):242-53. doi: 10.1016/j.cmet.2011.05.013.
375 Association of increased levels of MCP-1 and cathepsin-D in young onset type 2 diabetes patients (T2DM-Y) with severity of diabetic retinopathy.J Diabetes Complications. 2017 May;31(5):804-809. doi: 10.1016/j.jdiacomp.2017.02.017. Epub 2017 Mar 10.
376 Association between CUBN gene variants, type 2 diabetes and vitamin D concentrations in an elderly Greek population.J Steroid Biochem Mol Biol. 2020 Apr;198:105549. doi: 10.1016/j.jsbmb.2019.105549. Epub 2019 Nov 23.
377 [Ginkgo biloba extract enhances testosterone synthesis of Leydig cells in type 2 diabetic rats].Zhonghua Nan Ke Xue. 2008 Apr;14(4):371-6.
378 Genetic variant of the renin-angiotensin system and prevalence of type 2 diabetes mellitus: a modest but significant effect of aldosterone synthase.Acta Diabetol. 2014 Aug;51(4):595-9. doi: 10.1007/s00592-014-0561-7. Epub 2014 Feb 19.
379 Altered Protein Expression of Cardiac CYP2J and Hepatic CYP2C, CYP4A, and CYP4F in a Mouse Model of Type II Diabetes-A Link in the Onset and Development of Cardiovascular Disease?.Pharmaceutics. 2017 Oct 12;9(4):44. doi: 10.3390/pharmaceutics9040044.
380 Modulation of CYP450 Activities in Patients With Type 2 Diabetes.Clin Pharmacol Ther. 2019 Dec;106(6):1280-1289. doi: 10.1002/cpt.1496. Epub 2019 Jul 9.
381 CYP2C19 or CYP3A5 Genotyping Does Not Predict Clinical Response to Clopidogrel.J Clin Pharmacol. 2018 Oct;58(10):1274-1283. doi: 10.1002/jcph.1144. Epub 2018 May 3.
382 Expression of the skeletal muscle dystrophin-dystroglycan complex and syntrophin-nitric oxide synthase complex is severely affected in the type 2 diabetic Goto-Kakizaki rat.Eur J Cell Biol. 2005 Nov;84(11):867-83. doi: 10.1016/j.ejcb.2005.06.007.
383 Insulin and Glucose Alter Death-Associated Protein Kinase 3 (DAPK3) DNA Methylation in Human Skeletal Muscle.Diabetes. 2017 Mar;66(3):651-662. doi: 10.2337/db16-0882. Epub 2016 Dec 23.
384 Association between single nucleotide polymorphisms of delta/notch-like epidermal growth factor (EGF)-related receptor (DNER) and Delta-like 1 Ligand (DLL 1) with the risk of type 2 diabetes mellitus in a Chinese Han population.Cell Biochem Biophys. 2015 Jan;71(1):331-5. doi: 10.1007/s12013-014-0202-3.
385 Increased formation of neutrophil extracellular traps is associated with gut leakage in patients with type 1 but not type 2 diabetes.J Diabetes. 2019 Aug;11(8):665-673. doi: 10.1111/1753-0407.12892. Epub 2019 Jan 28.
386 Inhibition of DNA methyltransferase 1 increases nuclear receptor subfamily 4 group A member 1 expression and decreases blood glucose in type 2 diabetes.Oncotarget. 2016 Jun 28;7(26):39162-39170. doi: 10.18632/oncotarget.10043.
387 Co-expression changes of lncRNAs and mRNAs in the cervical sympathetic ganglia in diabetic cardiac autonomic neuropathic rats.J Neurosci Res. 2017 Aug;95(8):1690-1699. doi: 10.1002/jnr.24000. Epub 2016 Dec 19.
388 Altered foetoplacental vascular endothelial signalling to insulin in diabesity.Mol Aspects Med. 2019 Apr;66:40-48. doi: 10.1016/j.mam.2019.02.003. Epub 2019 Mar 8.
389 Involvement of NO and MEK/ERK pathway in enhancement of endothelin-1-induced mesenteric artery contraction in later-stage type 2 diabetic Goto-Kakizaki rat.Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1388-97. doi: 10.1152/ajpheart.00043.2009. Epub 2009 Mar 13.
390 Metaflammasome components in the human brain: a role in dementia with Alzheimer's pathology?.Brain Pathol. 2017 May;27(3):266-275. doi: 10.1111/bpa.12388. Epub 2016 Jun 8.
391 Specific PERK inhibitors enhanced glucose-stimulated insulin secretion in a mouse model of type 2 diabetes.Metabolism. 2019 Aug;97:87-91. doi: 10.1016/j.metabol.2018.12.007. Epub 2019 Jan 4.
392 GCN2 deficiency ameliorates cardiac dysfunction in diabetic mice by reducing lipotoxicity and oxidative stress.Free Radic Biol Med. 2019 Jan;130:128-139. doi: 10.1016/j.freeradbiomed.2018.10.445. Epub 2018 Oct 30.
393 ENSA expression correlates with attenuated tumor propagation in liver cancer.Biochem Biophys Res Commun. 2013 Dec 6;442(1-2):56-61. doi: 10.1016/j.bbrc.2013.10.165. Epub 2013 Nov 8.
394 Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic Cells for InVitro and InVivo Analysis.Cell Metab. 2019 Mar 5;29(3):745-754.e4. doi: 10.1016/j.cmet.2018.10.007. Epub 2018 Nov 15.
395 Adaptation to hypoxia in the diabetic rat kidney.Kidney Int. 2008 Jan;73(1):34-42. doi: 10.1038/sj.ki.5002567. Epub 2007 Oct 3.
396 EPHA4 regulates vascular smooth muscle cell contractility and is a sex-specific hypertension risk gene in individuals with type 2 diabetes.J Hypertens. 2019 Apr;37(4):775-789. doi: 10.1097/HJH.0000000000001948.
397 Cognitive, emotional and social phenotyping of mice in an observer-independent setting.Neurobiol Learn Mem. 2018 Apr;150:136-150. doi: 10.1016/j.nlm.2018.02.023. Epub 2018 Feb 21.
398 Identification of Estrogen-Related Receptor Agonists in the Tox21 Compound Library.Endocrinology. 2018 Feb 1;159(2):744-753. doi: 10.1210/en.2017-00658.
399 Thrombin stimulates insulin secretion via protease-activated receptor-3.Islets. 2015;7(4):e1118195. doi: 10.1080/19382014.2015.1118195.
400 Long-term administration of highly purified eicosapentaenoic acid ethyl ester improves blood coagulation abnormalities and dysfunction of vascular endothelial cells in Otsuka Long-Evans Tokushima fatty rats.Endocr J. 2003 Oct;50(5):603-11. doi: 10.1507/endocrj.50.603.
401 Fatty acid binding protein 4 (FABP4) as a potential biomarker reflecting myocardial lipid storage in type 2 diabetes.Metabolism. 2019 Jul;96:12-21. doi: 10.1016/j.metabol.2019.04.007. Epub 2019 Apr 15.
402 Direct association of a promoter polymorphism in the CD36/FAT fatty acid transporter gene with Type 2 diabetes mellitus and insulin resistance.Diabet Med. 2006 Aug;23(8):907-11. doi: 10.1111/j.1464-5491.2006.01888.x.
403 Hyposialylated IgG activates endothelial IgG receptor FcRIIB to promote obesity-induced insulin resistance.J Clin Invest. 2018 Jan 2;128(1):309-322. doi: 10.1172/JCI89333. Epub 2017 Nov 27.
404 Bioactivation of GPR40 Agonist MK-8666: Formation of Protein Adducts in Vitro from Reactive Acyl Glucuronide and Acyl CoA Thioester.Chem Res Toxicol. 2020 Jan 21;33(1):191-201. doi: 10.1021/acs.chemrestox.9b00226. Epub 2019 Oct 14.
405 Reduced expression of stearoyl-CoA desaturase-1, but not free fatty acid receptor 2 or 4 in subcutaneous adipose tissue of patients with newly diagnosed type 2 diabetes mellitus.Nutr Diabetes. 2018 Sep 7;8(1):49. doi: 10.1038/s41387-018-0054-9.
406 Effects of short chain fatty acid producing bacteria on epigenetic regulation of FFAR3 in type 2 diabetes and obesity.Gene. 2014 Mar 1;537(1):85-92. doi: 10.1016/j.gene.2013.11.081. Epub 2013 Dec 8.
407 Discovery of Small-Molecule Sulfonamide Fluorescent Probes for GPR120.Anal Chem. 2019 Dec 3;91(23):15235-15239. doi: 10.1021/acs.analchem.9b04157. Epub 2019 Nov 15.
408 Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain.Diabetes. 2019 Mar;68(3):654-664. doi: 10.2337/db18-0498. Epub 2018 Dec 6.
409 Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.Clin Pharmacol Ther. 2018 Apr;103(4):712-721. doi: 10.1002/cpt.798. Epub 2017 Nov 3.
410 Serum fibroblast growth factor 19 and endogenous islet beta cell function in type 2 diabetic patients.Diabetol Metab Syndr. 2019 Sep 24;11:79. doi: 10.1186/s13098-019-0475-1. eCollection 2019.
411 Fibroblast growth factor 23 levels decline following sleeve gastrectomy.Clin Endocrinol (Oxf). 2019 Jul;91(1):87-93. doi: 10.1111/cen.13981. Epub 2019 Apr 15.
412 Cost-effectiveness of the SLIMMER diabetes prevention intervention in Dutch primary health care: economic evaluation from a randomised controlled trial.BMC Health Serv Res. 2019 Nov 11;19(1):824. doi: 10.1186/s12913-019-4529-8.
413 Fructose-1,6-bisphosphatase: genetic and physical mapping to human chromosome 9q22.3 and evaluation in non-insulin-dependent diabetes mellitus.Genomics. 1995 Sep 1;29(1):187-94. doi: 10.1006/geno.1995.1230.
414 Gene expression profiling demonstrates WNT/-catenin pathway genes alteration in Mexican patients with colorectal cancer and diabetes mellitus.J BUON. 2017 Sep-Oct;22(5):1107-1114.
415 The human HNF-3 genes: cloning, partial sequence and mutation screening in patients with impaired glucose homeostasis.Hum Hered. 2000 Nov-Dec;50(6):370-81. doi: 10.1159/000022943.
416 Follistatins in glucose regulation in healthy and obese individuals.Diabetes Obes Metab. 2019 Mar;21(3):683-690. doi: 10.1111/dom.13572. Epub 2018 Dec 3.
417 Gene-gene interactions lead to higher risk for development of type 2 diabetes in a Chinese Han population: a prospective nested case-control study.Lipids Health Dis. 2018 Jul 28;17(1):179. doi: 10.1186/s12944-018-0813-6.
418 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.BMC Genet. 2017 Dec 8;18(1):105. doi: 10.1186/s12863-017-0572-9.
419 Type 1 diabetes defined by severe insulin deficiency occurs after 30years of age and is commonly treated as type 2 diabetes.Diabetologia. 2019 Jul;62(7):1167-1172. doi: 10.1007/s00125-019-4863-8. Epub 2019 Apr 10.
420 The association between GAD65 antibody levels and incident Type 2 Diabetes Mellitus in an adult population: A meta-analysis.Metabolism. 2019 Jun;95:1-7. doi: 10.1016/j.metabol.2019.03.001. Epub 2019 Mar 8.
421 Galanin peptide family regulation of glucose metabolism.Front Neuroendocrinol. 2020 Jan;56:100801. doi: 10.1016/j.yfrne.2019.100801. Epub 2019 Nov 6.
422 The effect of hypergastrinemia following sleeve gastrectomy and pantoprazole on type 2 diabetes mellitus and beta-cell mass in Goto-Kakizaki rats.J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22.
423 Immunohistochemical detection of vimentin in pancreatic islet - and -cells of macrosomic infants of diabetic and nondiabetic mothers.Early Hum Dev. 2018 Feb;117:44-49. doi: 10.1016/j.earlhumdev.2017.12.009. Epub 2017 Dec 21.
424 Evaluation of the association between GHR exon 3 polymorphism and polycystic ovary syndrome among Han Chinese women.Growth Horm IGF Res. 2011 Oct;21(5):248-51. doi: 10.1016/j.ghir.2011.07.002. Epub 2011 Aug 5.
425 Cholesterol metabolism and Cx43, Cx46, and Cx50 gap junction protein expression and localization in normal and diabetic and obese ob/ob and db/db mouse testes.Am J Physiol Endocrinol Metab. 2018 Jan 1;314(1):E21-E38. doi: 10.1152/ajpendo.00215.2017. Epub 2017 Aug 29.
426 Efficacy and Safety of Biosimilar SAR342434 Insulin Lispro in Adults with Type 2 Diabetes, Also Using Insulin Glargine: SORELLA 2 Study.Diabetes Technol Ther. 2018 Jan;20(1):49-58. doi: 10.1089/dia.2017.0281. Epub 2017 Dec 12.
427 TGR5 agonist ameliorates insulin resistance in the skeletal muscles and improves glucose homeostasis in diabetic mice.Metabolism. 2019 Oct;99:45-56. doi: 10.1016/j.metabol.2019.07.003. Epub 2019 Jul 8.
428 Optimisation of novel 4, 8-disubstituted dihydropyrimido[5,4-b][1,4]oxazine derivatives as potent GPR 119 agonists.J Enzyme Inhib Med Chem. 2020 Dec;35(1):50-58. doi: 10.1080/14756366.2019.1681988.
429 Changes in obestatin gene and GPR39 receptor expression in peripheral tissues of rat models of obesity, type 1 and type 2 diabetes.J Diabetes. 2017 Apr;9(4):353-361. doi: 10.1111/1753-0407.12417. Epub 2016 Jul 28.
430 Novel protective effect of O-1602 and abnormal cannabidiol, GPR55 agonists, on ER stress-induced apoptosis in pancreatic -cells.Biomed Pharmacother. 2019 Mar;111:1176-1186. doi: 10.1016/j.biopha.2018.12.126. Epub 2019 Jan 15.
431 Evaluation of the oxidative stress-related genes ALOX5, ALOX5AP, GPX1, GPX3 and MPO for contribution to the risk of type 2 diabetes mellitus in the Han Chinese population.Diab Vasc Dis Res. 2018 Jul;15(4):336-339. doi: 10.1177/1479164118755044. Epub 2018 Jan 31.
432 A variant of GRK5 is associated with the therapeutic efficacy of repaglinide in Chinese Han patients with type 2 diabetes mellitus.Drug Dev Res. 2018 May;79(3):129-135. doi: 10.1002/ddr.21426. Epub 2018 Apr 16.
433 Plasma gelsolin levels decrease in diabetic state and increase upon treatment with F-actin depolymerizing versions of gelsolin.J Diabetes Res. 2014;2014:152075. doi: 10.1155/2014/152075. Epub 2014 Nov 12.
434 A study on correlation between oxidative stress parameters and inflammatory markers in type 2 diabetic patients with kidney dysfunction in north Indian population.J Cell Biochem. 2019 Apr;120(4):4892-4902. doi: 10.1002/jcb.27763. Epub 2018 Sep 27.
435 Serum and salivary ferritin and Hepcidin levels in patients with chronic periodontitis and type 2 diabetes mellitus.BMC Oral Health. 2018 Apr 10;18(1):63. doi: 10.1186/s12903-018-0524-4.
436 Inhibition of COX2/PGD2-Related Autophagy Is Involved in the Mechanism of Brain Injury in T2DM Rat.Front Cell Neurosci. 2019 Feb 27;13:68. doi: 10.3389/fncel.2019.00068. eCollection 2019.
437 Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling.Diabetes. 2019 Apr;68(4):747-760. doi: 10.2337/db18-0671. Epub 2019 Jan 22.
438 Mitochondrial-Derived Peptides Are Down Regulated in Diabetes Subjects.Front Endocrinol (Lausanne). 2019 May 31;10:331. doi: 10.3389/fendo.2019.00331. eCollection 2019.
439 HSP22 suppresses diabetes-induced endothelial injury by inhibiting mitochondrial reactive oxygen species formation.Redox Biol. 2019 Feb;21:101095. doi: 10.1016/j.redox.2018.101095. Epub 2019 Jan 3.
440 Serotonin receptor 3B polymorphisms are associated with type 2 diabetes: The Korean Genome and Epidemiology Study.Diabetes Res Clin Pract. 2019 Jul;153:76-85. doi: 10.1016/j.diabres.2019.05.032. Epub 2019 May 29.
441 Cortisol responses to emotional stress in men: association with a functional polymorphism in the 5HTR2C gene.Biol Psychol. 2012 Jan;89(1):94-8. doi: 10.1016/j.biopsycho.2011.09.013. Epub 2011 Oct 1.
442 ICOS/ICOSL upregulation mediates inflammatory response and endothelial dysfunction in type 2 diabetes mellitus.Eur Rev Med Pharmacol Sci. 2018 Dec;22(24):8898-8908. doi: 10.26355/eurrev_201812_16659.
443 The association of soluble IGF2R and IGF2R gene polymorphism with type 2 diabetes.J Diabetes Res. 2015;2015:216383. doi: 10.1155/2015/216383. Epub 2015 Apr 2.
444 Copeptin and insulin-like growth factor binding protein-1 during follow-up after an acute myocardial infarction in patients with type 2 diabetes: A report from the Diabetes Mellitus Insulin-Glucose Infusion in Acute Myocardial Infarction 2 cohort.Diab Vasc Dis Res. 2019 Jan;16(1):22-27. doi: 10.1177/1479164118804451. Epub 2018 Oct 11.
445 Insulin-Like Growth Factor Binding Protein 2 (IGFBP-2) and the Risk of Developing Type 2 Diabetes.Diabetes. 2019 Jan;68(1):188-197. doi: 10.2337/db18-0620. Epub 2018 Nov 5.
446 Central IKK2 Inhibition Ameliorates Air Pollution-Mediated Hepatic Glucose and Lipid Metabolism Dysfunction in Mice With Type II Diabetes.Toxicol Sci. 2018 Jul 1;164(1):240-249. doi: 10.1093/toxsci/kfy079.
447 Genetic variation at IL12B, IL23R and IL23A is associated with psoriasis severity, psoriatic arthritis and type 2 diabetes mellitus.J Dermatol Sci. 2014 Sep;75(3):167-72. doi: 10.1016/j.jdermsci.2014.05.010. Epub 2014 Jun 11.
448 Anti-Inflammatory Effect of Combined Sitagliptin and Vitamin D3 on Cytokines Profile in Patients with Type 2 Diabetes Mellitus.J Interferon Cytokine Res. 2019 May;39(5):293-301. doi: 10.1089/jir.2018.0144. Epub 2019 Mar 11.
449 Levels of adiponectin, C-reactive protein and interleukin-1 receptor antagonist are associated with insulin sensitivity: a population-based study.Diabetes Metab Res Rev. 2008 Jul-Aug;24(5):378-83. doi: 10.1002/dmrr.831.
450 IL-20 contributes to low grade inflammation and weight gain in the Psammomys obesus.Int Immunopharmacol. 2017 Apr;45:53-67. doi: 10.1016/j.intimp.2017.01.031. Epub 2017 Feb 7.
451 Emerging role of Interleukins IL-23/IL-17 axis and biochemical markers in the pathogenesis of Type 2 Diabetes: Association with age and gender in human subjects.Int J Biol Macromol. 2017 Dec;105(Pt 1):1279-1288. doi: 10.1016/j.ijbiomac.2017.07.155. Epub 2017 Jul 27.
452 Serum levels of IL-32 in patients with type 2 diabetes mellitus and its relationship with TNF- and IL-6.Cytokine. 2020 Jan;125:154832. doi: 10.1016/j.cyto.2019.154832. Epub 2019 Aug 31.
453 IL-33 at the Crossroads of Metabolic Disorders and Immunity.Front Endocrinol (Lausanne). 2019 Jan 30;10:26. doi: 10.3389/fendo.2019.00026. eCollection 2019.
454 Effects of sitagliptin and vitamin D3 on T helper cell transcription factors and cytokine production in clinical subgroups of type 2 diabetes mellitus: highlights upregulation of FOXP3 and IL-37.Immunopharmacol Immunotoxicol. 2019 Apr;41(2):299-311. doi: 10.1080/08923973.2019.1593447. Epub 2019 Mar 25.
455 Interleukin-4 (IL4) -590C/T (rs2243250) gene polymorphism is not associated with diabetic nephropathy (DN) in Caucasians with type 2 diabetes mellitus (T2DM).Bosn J Basic Med Sci. 2018 Nov 7;18(4):347-351. doi: 10.17305/bjbms.2018.2688.
456 Association of polymorphisms in the MyD88, IRAK4 and TRAF6 genes and susceptibility to type 2 diabetes mellitus and diabetic nephropathy in a southern Han Chinese population.Mol Cell Endocrinol. 2016 Jul 5;429:114-9. doi: 10.1016/j.mce.2016.04.003. Epub 2016 Apr 8.
457 Correlation between polymorphism of platelet alloantigen genes HPA-1-5 and type 2 diabetes complication by carotid atherosclerosis in a Chinese population.Genet Mol Res. 2015 May 4;14(2):4607-15. doi: 10.4238/2015.May.4.19.
458 25-Hydroxyvitamin D(3) -enhanced PTPN2 positively regulates periodontal inflammation through the JAK/STAT pathway in human oral keratinocytes and a mouse model of type 2 diabetes mellitus.J Periodontal Res. 2018 Jun;53(3):467-477. doi: 10.1111/jre.12535. Epub 2018 Mar 8.
459 No evidence for mutations in a putative beta-cell ATP-sensitive K+ channel subunit in MODY, NIDDM, or GDM.Diabetes. 1995 May;44(5):597-600. doi: 10.2337/diab.44.5.597.
460 Mitochondrial FAD-glycerophosphate dehydrogenase and G-protein-coupled inwardly rectifying K+ channel: No evidence for linkage in maturity-onset diabetes of the young or NIDDM.Diabetes. 1996 May;45(5):639-41. doi: 10.2337/diab.45.5.639.
461 Multiple genetic variations confer risks for obesity and type 2 diabetes mellitus in arab descendants from UAE.Int J Obes (Lond). 2018 Jul;42(7):1345-1353. doi: 10.1038/s41366-018-0057-6. Epub 2018 Mar 12.
462 Downregulation of BK channel function and protein expression in coronary arteriolar smooth muscle cells of type 2 diabetic patients.Cardiovasc Res. 2019 Jan 1;115(1):145-153. doi: 10.1093/cvr/cvy137.
463 Genetic variants of IDE-KIF11-HHEX at 10q23.33 associated with type 2 diabetes risk: a fine-mapping study in Chinese population.PLoS One. 2012;7(4):e35060. doi: 10.1371/journal.pone.0035060. Epub 2012 Apr 10.
464 Sympathetic Hyperactivity and Sleep Disorders in Individuals With Type 2 Diabetes.Front Endocrinol (Lausanne). 2019 Nov 1;10:752. doi: 10.3389/fendo.2019.00752. eCollection 2019.
465 Genetic interactions of KIR and G1M immunoglobulin allotypes differ in obese from non-obese individuals with type 2 diabetes.Mol Immunol. 2008 Aug;45(14):3857-62. doi: 10.1016/j.molimm.2008.06.004. Epub 2008 Jul 15.
466 Clinical implication of alterations in serum Klotho levels in patients with type 2 diabetes mellitus and its associated complications.J Diabetes Complications. 2018 Oct;32(10):922-930. doi: 10.1016/j.jdiacomp.2018.06.002. Epub 2018 Jun 12.
467 GONADOPENIA AND AGING IN MEN.Endocr Pract. 2018 Apr;24(4):375-385. doi: 10.4158/EP-2017-0131.
468 IL-17 production by NKG2D-expressing CD56+ T cells in type 2 diabetes.Mol Immunol. 2019 Feb;106:22-28. doi: 10.1016/j.molimm.2018.12.008. Epub 2018 Dec 18.
469 Bradykinin, insulin, and glycemia responses to exercise performed above and below lactate threshold in individuals with type 2 diabetes.Braz J Med Biol Res. 2017 Sep 12;50(11):e6400. doi: 10.1590/1414-431X20176400.
470 Urinary NGAL and RBP Are Biomarkers of Normoalbuminuric Renal Insufficiency in Type 2 Diabetes Mellitus.J Immunol Res. 2019 Sep 15;2019:5063089. doi: 10.1155/2019/5063089. eCollection 2019.
471 A Combination of Human Embryonic Stem Cell-Derived Pancreatic Endoderm Transplant with LDHA-Repressing miRNA Can Attenuate High-Fat Diet Induced Type II Diabetes in Mice.J Diabetes Res. 2015;2015:796912. doi: 10.1155/2015/796912. Epub 2015 Dec 3.
472 Galectin-3 and risk of cardiovascular events and all-cause mortality in type 2 diabetes.Diabetes Metab Res Rev. 2019 Feb;35(2):e3093. doi: 10.1002/dmrr.3093. Epub 2018 Nov 15.
473 Factors influencing longitudinal changes of circulating liver enzyme concentrations in subjects randomized to placebo in four clinical trials.Am J Physiol Gastrointest Liver Physiol. 2019 Mar 1;316(3):G372-G386. doi: 10.1152/ajpgi.00051.2018. Epub 2018 Nov 29.
474 Increased serum miR-7 is a promising biomarker for type 2 diabetes mellitus and its microvascular complications.Diabetes Res Clin Pract. 2017 Aug;130:171-179. doi: 10.1016/j.diabres.2017.06.005. Epub 2017 Jun 11.
475 Capsaicin reduces Alzheimer-associated tau changes in the hippocampus of type 2 diabetes rats.PLoS One. 2017 Feb 22;12(2):e0172477. doi: 10.1371/journal.pone.0172477. eCollection 2017.
476 Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease.Clin Sci (Lond). 2017 Jun 7;131(12):1301-1315. doi: 10.1042/CS20170175. Print 2017 Jun 1.
477 Expression of LRP1 and CHOP genes associated with peripheral neuropathy in type 2 diabetes mellitus: Correlations with nerve conduction studies.Gene. 2019 Jun 20;702:114-122. doi: 10.1016/j.gene.2019.02.105. Epub 2019 Mar 19.
478 Increased megalin expression in early type 2 diabetes: role of insulin-signaling pathways.Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1191-F1207. doi: 10.1152/ajprenal.00210.2018. Epub 2018 Jun 27.
479 Upregulation of SLAMF3 on human T cells is induced by palmitic acid through the STAT5-PI3K/Akt pathway and features the chronic inflammatory profiles of type 2 diabetes.Cell Death Dis. 2019 Jul 22;10(8):559. doi: 10.1038/s41419-019-1791-y.
480 Association of POL1, MALT1, MC4R, PHLPP and DSEL single nucleotide polymorphisms in chromosome 18q region with type 2 diabetes in Tunisians.Gene. 2013 Sep 15;527(1):243-7. doi: 10.1016/j.gene.2013.05.015. Epub 2013 May 29.
481 Sex-Dependent Role of Estrogen Sulfotransferase and Steroid Sulfatase in Metabolic Homeostasis.Adv Exp Med Biol. 2017;1043:455-469. doi: 10.1007/978-3-319-70178-3_21.
482 Acebutolol, a Cardioselective Beta Blocker, Promotes Glucose Uptake in Diabetic Model Cells by Inhibiting JNK-JIP1 Interaction.Biomol Ther (Seoul). 2018 Sep 1;26(5):458-463. doi: 10.4062/biomolther.2017.123.
483 Balanites aegyptiaca ameliorates insulin secretion and decreases pancreatic apoptosis in diabetic rats: Role of SAPK/JNK pathway.Biomed Pharmacother. 2018 Jun;102:1084-1091. doi: 10.1016/j.biopha.2018.03.167. Epub 2018 Apr 5.
484 Presence of White Matter Lesions Associated with Diabetes-Associated Cognitive Decline in Male Rat Models of Pre-Type 2 Diabetes.Med Sci Monit. 2019 Dec 18;25:9679-9689. doi: 10.12659/MSM.918557.
485 Vitamin D effects on sphingosine 1-phosphate signaling and metabolism in monocytes from type 2 diabetes patients and controls.J Steroid Biochem Mol Biol. 2019 Feb;186:130-135. doi: 10.1016/j.jsbmb.2018.10.005. Epub 2018 Oct 15.
486 -Glucosidase inhibitory effect of anthocyanins from Cinnamomum camphora fruit: Inhibition kinetics and mechanistic insights through in vitro and in silico studies.Int J Biol Macromol. 2020 Jan 15;143:696-703. doi: 10.1016/j.ijbiomac.2019.09.091. Epub 2019 Sep 12.
487 Characterization of Large Copy Number Variation in Mexican Type 2 Diabetes subjects.Sci Rep. 2017 Dec 6;7(1):17105. doi: 10.1038/s41598-017-17361-7.
488 Hippocampal neurovascular and hypothalamic-pituitary-adrenal axis alterations in spontaneously type 2 diabetic GK rats.Exp Neurol. 2010 Mar;222(1):125-34. doi: 10.1016/j.expneurol.2009.12.022. Epub 2010 Jan 4.
489 Association between matrix metallopeptidase 1 and type 2 diabetes mellitus coexisting with coronary heart disease in a Han Chinese population.Genet Mol Res. 2016 Jun 10;15(2). doi: 10.4238/gmr.15027938.
490 Cardiovascular organ damage in type 2 diabetes mellitus: the role of lipids and inflammation.Cardiovasc Diabetol. 2019 May 10;18(1):61. doi: 10.1186/s12933-019-0865-6.
491 Matrix metalloproteinase-8 analysis in patients with periodontal disease with prediabetes or type 2 diabetes mellitus: A systematic review.Arch Oral Biol. 2018 Mar;87:43-51. doi: 10.1016/j.archoralbio.2017.12.008. Epub 2017 Dec 12.
492 Serum Myostatin is Upregulated in Obesity and Correlates with Insulin Resistance in Humans.Exp Clin Endocrinol Diabetes. 2019 Sep;127(8):550-556. doi: 10.1055/a-0641-5546. Epub 2018 Aug 3.
493 Diabetic Goto Kakizaki rats as well as type 2 diabetic patients show a decreased diurnal serum melatonin level and an increased pancreatic melatonin-receptor status.J Pineal Res. 2006 Mar;40(2):135-43. doi: 10.1111/j.1600-079X.2005.00287.x.
494 Tissue-specific alterations of methyl group metabolism with DNA hypermethylation in the Zucker (type 2) diabetic fatty rat.Diabetes Metab Res Rev. 2012 Feb;28(2):123-31. doi: 10.1002/dmrr.1281.
495 A common functional exon polymorphism in the microsomal triglyceride transfer protein gene is associated with type 2 diabetes, impaired glucose metabolism and insulin levels.J Hum Genet. 2006;51(6):567-574. doi: 10.1007/s10038-006-0400-y. Epub 2006 May 24.
496 Association of AluYb8 insertion/deletion polymorphism in the MUTYH gene with mtDNA maintain in the type 2 diabetes mellitus patients.Mol Cell Endocrinol. 2015 Jul 5;409:33-40. doi: 10.1016/j.mce.2015.03.019. Epub 2015 Mar 27.
497 Salivary -amylase copy number is not associated with weight trajectories and glycemic improvements following clinical weight loss: results from a 2-phase dietary intervention study.Am J Clin Nutr. 2019 Apr 1;109(4):1029-1037. doi: 10.1093/ajcn/nqy363.
498 The identification of gene signature and critical pathway associated with childhood-onset type 2 diabetes.PeerJ. 2019 Feb 6;7:e6343. doi: 10.7717/peerj.6343. eCollection 2019.
499 Molecular mechanisms linking peri-implantitis and type 2 diabetes mellitus revealed by transcriptomic analysis.PeerJ. 2019 Jun 21;7:e7124. doi: 10.7717/peerj.7124. eCollection 2019.
500 A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS).Diabetologia. 2009 Jul;52(7):1326-33. doi: 10.1007/s00125-009-1373-0. Epub 2009 May 9.
501 Expression levels of enzymes generating NO and CO in islets of murine and human diabetes.Biochem Biophys Res Commun. 2019 Dec 3;520(2):473-478. doi: 10.1016/j.bbrc.2019.10.055. Epub 2019 Oct 11.
502 MicroRNAs 342 and 450 together with NOX-4 activity and their association with coronary artery disease in diabetes.Diabetes Metab Res Rev. 2019 Jul;35(5):e3130. doi: 10.1002/dmrr.3130. Epub 2019 Apr 8.
503 Association of Genetically Enhanced Lipoprotein Lipase-Mediated Lipolysis and Low-Density Lipoprotein Cholesterol-Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes.JAMA Cardiol. 2018 Oct 1;3(10):957-966. doi: 10.1001/jamacardio.2018.2866.
504 Determinants of glucose metabolism and the role of NPY in the progression of insulin resistance in chronic migraine.Cephalalgia. 2018 Oct;38(11):1773-1781. doi: 10.1177/0333102417748928. Epub 2017 Dec 20.
505 Synchronized human skeletal myotubes of lean, obese and type 2 diabetic patients maintain circadian oscillation of clock genes.Sci Rep. 2016 Oct 19;6:35047. doi: 10.1038/srep35047.
506 Genetic variation within the NR1H2 gene encoding liver X receptor associates with insulin secretion in subjects at increased risk for type 2 diabetes.J Mol Med (Berl). 2011 Jan;89(1):75-81. doi: 10.1007/s00109-010-0687-1. Epub 2010 Nov 2.
507 A novel epigenetic mechanism of FXR inhibiting GLP-1 secretion via miR-33 and its downstream targets.Biochem Biophys Res Commun. 2019 Oct 1;517(4):629-635. doi: 10.1016/j.bbrc.2019.07.079. Epub 2019 Aug 3.
508 Mineralocorticoid Antagonism and Diabetic Kidney Disease.Curr Diab Rep. 2019 Jan 23;19(1):4. doi: 10.1007/s11892-019-1123-8.
509 Insulin sensitivity linked skeletal muscle Nr4a1 DNA methylation is programmed by the maternal diet and modulated by voluntary exercise in mice.J Nutr Biochem. 2018 Jul;57:86-92. doi: 10.1016/j.jnutbio.2018.03.015. Epub 2018 Mar 21.
510 Diabetes as a prognostic factor in HER-2 positive breast cancer patients treated with targeted therapy.Breast Cancer. 2019 Sep;26(5):672-680. doi: 10.1007/s12282-019-00967-2. Epub 2019 Mar 29.
511 Inhibition of vascular adventitial remodeling by netrin-1 in diabetic rats.J Endocrinol. 2020 Mar;244(3):445-458. doi: 10.1530/JOE-19-0258.
512 A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies.Diabetes. 2019 Aug;68(8):1649-1662. doi: 10.2337/db19-0109. Epub 2019 May 24.
513 Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose level in the Japanese general population.J Epidemiol. 2014;24(5):379-84. doi: 10.2188/jea.je20140002. Epub 2014 Jul 5.
514 Olfactomedin 4 Deletion Improves Male Mouse Glucose Intolerance and Insulin Resistance Induced by a High-Fat Diet.Endocrinology. 2018 Sep 1;159(9):3235-3244. doi: 10.1210/en.2018-00451.
515 Overexpression of scavenger receptor and infiltration of macrophage in epicardial adipose tissue of patients with ischemic heart disease and diabetes.J Transl Med. 2019 Mar 20;17(1):95. doi: 10.1186/s12967-019-1842-2.
516 Association of insulin, C-peptide and blood lipid patterns in patients with impaired glucose regulation.BMC Endocr Disord. 2019 Jul 15;19(1):75. doi: 10.1186/s12902-019-0400-5.
517 Type 2 diabetes specifically attenuates purinergic skin vasodilatation without affecting muscarinic and nicotinic skin vasodilatation and sweating.Exp Physiol. 2018 Feb 1;103(2):212-221. doi: 10.1113/EP086694. Epub 2018 Jan 10.
518 A computational approach to explore and identify potential herbal inhibitors for the p21-activated kinase 1 (PAK1).J Biomol Struct Dyn. 2020 Aug;38(12):3514-3526. doi: 10.1080/07391102.2019.1659855. Epub 2019 Sep 5.
519 Functional analysis of PCSK2 coding variants: A founder effect in the Old Order Amish population.Diabetes Res Clin Pract. 2017 Sep;131:82-90. doi: 10.1016/j.diabres.2017.06.023. Epub 2017 Jul 3.
520 Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia.Transl Psychiatry. 2018 Nov 23;8(1):252. doi: 10.1038/s41398-018-0304-6.
521 Metabolomics Signatures in Type 2 Diabetes: A Systematic Review and Integrative Analysis.J Clin Endocrinol Metab. 2020 Apr 1;105(4):dgz240. doi: 10.1210/clinem/dgz240.
522 PDE5 Inhibitor Tadalafil and Hydroxychloroquine Cotreatment Provides Synergistic Protection against Type 2 Diabetes and Myocardial Infarction in Mice.J Pharmacol Exp Ther. 2017 Apr;361(1):29-38. doi: 10.1124/jpet.116.239087. Epub 2017 Jan 25.
523 Insulin downregulates pyruvate dehydrogenase kinase (PDK) mRNA: potential mechanism contributing to increased lipid oxidation in insulin-resistant subjects.Mol Genet Metab. 1998 Oct;65(2):181-6. doi: 10.1006/mgme.1998.2748.
524 Corosolic acid isolated from Eriobotrya japonica leaves reduces glucose level in human hepatocellular carcinoma cells, zebrafish and rats.Sci Rep. 2019 Mar 13;9(1):4388. doi: 10.1038/s41598-019-40934-7.
525 Systematic Meta-analysis Revealed an Association of PGC-1 rs8192678 Polymorphism in Type 2 Diabetes Mellitus.Dis Markers. 2019 Mar 3;2019:2970401. doi: 10.1155/2019/2970401. eCollection 2019.
526 Plasma Placental Growth Factor Concentrations Are Elevated Well in Advance of Type 2 Diabetes Mellitus Onset: Prospective Data From the WHS.J Am Heart Assoc. 2019 Aug 6;8(15):e012790. doi: 10.1161/JAHA.119.012790. Epub 2019 Jul 19.
527 Type 2 Diabetes, but Not Insulin (Analog) Treatment, Is Associated With More Advanced Stages of Breast Cancer: A National Linkage of Cancer and Pharmacy Registries.Diabetes Care. 2019 Mar;42(3):434-442. doi: 10.2337/dc18-2146. Epub 2019 Jan 24.
528 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.Nat Genet. 2018 Apr;50(4):559-571. doi: 10.1038/s41588-018-0084-1. Epub 2018 Apr 9.
529 Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits.BMC Med Genet. 2008 Dec 26;9:118. doi: 10.1186/1471-2350-9-118.
530 Polymorphisms in platelet glycoproteins Ia and IIIa are associated with arterial thrombosis and carotid atherosclerosis in type 2 diabetes.Thromb Haemost. 2010 Mar;103(3):630-7. doi: 10.1160/TH09-07-0453. Epub 2010 Jan 13.
531 Role of vitamin D in risk factors of patients with type 2 diabetes mellitus.Med Clin (Barc). 2020 Mar 13;154(5):151-156. doi: 10.1016/j.medcli.2019.04.019. Epub 2019 Jun 26.
532 Trans-palmitoleic acid (trans-9-C16:1, or trans-C16:1 n-7): Nutritional impacts, metabolism, origin, compositional data, analytical methods and chemical synthesis. A review.Biochimie. 2020 Feb;169:144-160. doi: 10.1016/j.biochi.2019.12.004. Epub 2019 Dec 16.
533 A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene.Hum Mol Genet. 1997 Sep;6(9):1401-8. doi: 10.1093/hmg/6.9.1401.
534 Interfering PLD1-PED/PEA15 interaction using self-inhibitory peptides: An in silico study to discover novel therapeutic candidates against type 2 diabetes.Saudi J Biol Sci. 2019 Jan;26(1):160-164. doi: 10.1016/j.sjbs.2018.08.020. Epub 2018 Aug 22.
535 Circulating miR-30c as a predictive biomarker of type 2 diabetes mellitus with coronary heart disease by regulating PAI-1/VN interactions.Life Sci. 2019 Dec 15;239:117092. doi: 10.1016/j.lfs.2019.117092. Epub 2019 Nov 21.
536 Diverse type 2 diabetes genetic risk factors functionally converge in a phenotype-focused gene network.PLoS Comput Biol. 2017 Oct 23;13(10):e1005816. doi: 10.1371/journal.pcbi.1005816. eCollection 2017 Oct.
537 Low-carbohydrate diet by staple change attenuates postprandial GIP and CPR levels in type 2 diabetes patients.J Diabetes Complications. 2019 Nov;33(11):107415. doi: 10.1016/j.jdiacomp.2019.107415. Epub 2019 Aug 15.
538 Free fatty acid-induced PP2A hyperactivity selectively impairs hepatic insulin action on glucose metabolism.PLoS One. 2011;6(11):e27424. doi: 10.1371/journal.pone.0027424. Epub 2011 Nov 7.
539 Potential Nexus of Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Insulin Resistance Between Hepatic and Peripheral Tissues.Front Pharmacol. 2019 Jan 14;9:1566. doi: 10.3389/fphar.2018.01566. eCollection 2018.
540 Relaxin Inhibits Cardiac Fibrosis in Diabetic Rats: Roles of Protein Kinase C.Exp Clin Endocrinol Diabetes. 2018 May;126(5):298-305. doi: 10.1055/s-0043-116946. Epub 2017 Sep 11.
541 PKC contributes to lipid-induced insulin resistance through cross talk with p70S6K and through previously unknown regulators of insulin signaling.Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8996-E9005. doi: 10.1073/pnas.1804379115. Epub 2018 Sep 4.
542 PKC Is Essential for Pancreatic -Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2.Diabetes. 2016 May;65(5):1283-96. doi: 10.2337/db15-1398. Epub 2016 Feb 11.
543 Lysosomal degradation of newly formed insulin granules contributes to cell failure in diabetes.Nat Commun. 2019 Jul 25;10(1):3312. doi: 10.1038/s41467-019-11170-4.
544 Methylation changes in the peripheral blood of Filipinos with type 2 diabetes suggest spurious transcription initiation at TXNIP.Hum Mol Genet. 2019 Dec 15;28(24):4208-4218. doi: 10.1093/hmg/ddz262.
545 Anti-interleukin-1 treatment in patients with rheumatoid arthritis and type 2 diabetes (TRACK): A multicentre, open-label, randomised controlled trial.PLoS Med. 2019 Sep 12;16(9):e1002901. doi: 10.1371/journal.pmed.1002901. eCollection 2019 Sep.
546 Presenilin-1 Established ER-Ca(2+) Leak: a Follow Up on Its Importance for the Initial Insulin Secretion in Pancreatic Islets and -Cells upon Elevated Glucose.Cell Physiol Biochem. 2019;53(3):573-586. doi: 10.33594/000000158.
547 Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1 alpha and PPAR beta/delta gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus. Int J Obes (Lond). 2007 Aug;31(8):1302-10. doi: 10.1038/sj.ijo.0803567. Epub 2007 Feb 20.
548 mRNA expression of platelet activating factor receptor (PAFR) in peripheral blood mononuclear cells is associated with albuminuria and vascular dysfunction in patients with type 2 diabetes.Diabetes Res Clin Pract. 2018 Feb;136:124-133. doi: 10.1016/j.diabres.2017.11.028. Epub 2017 Dec 14.
549 The role of Cox-2 and prostaglandin E(2) receptor EP3 in pancreatic -cell death.FASEB J. 2019 Apr;33(4):4975-4986. doi: 10.1096/fj.201801823R. Epub 2019 Jan 10.
550 Peptide YY (1-36) peptides from phylogenetically ancient fish targeting mammalian neuropeptide Y1 receptors demonstrate potent effects on pancreatic -cell function, growth and survival.Diabetes Obes Metab. 2020 Mar;22(3):404-416. doi: 10.1111/dom.13908. Epub 2019 Dec 9.
551 Functional and association analysis of an Amerindian-derived population-specific p.(Thr280Met) variant in RBPJL, a component of the PTF1 complex.Eur J Hum Genet. 2018 Feb;26(2):238-246. doi: 10.1038/s41431-017-0062-6. Epub 2018 Jan 4.
552 RORB and RORC associate with human islet dysfunction and inhibit insulin secretion in INS-1 cells.Islets. 2019;11(1):10-20. doi: 10.1080/19382014.2019.1566684. Epub 2019 Feb 14.
553 Cloning of a human insulin-stimulated protein kinase (ISPK-1) gene and analysis of coding regions and mRNA levels of the ISPK-1 and the protein phosphatase-1 genes in muscle from NIDDM patients.Diabetes. 1995 Jan;44(1):90-7. doi: 10.2337/diab.44.1.90.
554 Control of hyperglycemia in male mice by leflunomide: mechanisms of action.J Endocrinol. 2018 Apr;237(1):43-58. doi: 10.1530/JOE-17-0536.
555 Linked magnolol dimer as a selective PPAR agonist - Structure-based rational design, synthesis, and bioactivity evaluation.Sci Rep. 2017 Oct 20;7(1):13002. doi: 10.1038/s41598-017-12628-5.
556 Association between Single-nucleotide Polymorphisms of RXRG and Genetic Susceptibility to Type 2 Diabetes in South China.Curr Mol Med. 2020;20(6):408-414. doi: 10.2174/1566524020666191206163951.
557 Blood expression of matrix metalloproteinases 8 and 9 and of their inducers S100A8 and S100A9 supports diagnosis and prognosis of PDAC-associated diabetes mellitus.Clin Chim Acta. 2016 May 1;456:24-30. doi: 10.1016/j.cca.2016.02.018. Epub 2016 Mar 1.
558 Polymorphisms of the scavenger receptor class B member 1 are associated with insulin resistance with evidence of gene by sex interaction.J Clin Endocrinol Metab. 2009 May;94(5):1789-96. doi: 10.1210/jc.2008-2800. Epub 2009 Mar 10.
559 Modulatory effect of inulin with soya isoflavones on plasma lipid profile and liver SCD-18 index in rats with induced type-2 diabetes mellitus.Histol Histopathol. 2019 Oct;34(10):1131-1140. doi: 10.14670/HH-18-113. Epub 2019 Apr 8.
560 BARI 2D: A Reanalysis Focusing on Cardiovascular Events.Mayo Clin Proc. 2019 Nov;94(11):2249-2262. doi: 10.1016/j.mayocp.2019.04.015. Epub 2019 Oct 4.
561 Suppression of Hepatic FLOT1 (Flotillin-1) by Type 2 Diabetes Mellitus Impairs the Disposal of Remnant Lipoproteins via Syndecan-1.Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):102-113. doi: 10.1161/ATVBAHA.117.310358. Epub 2017 Nov 21.
562 Association of P213S polymorphism of the L-selectin gene with type 2 diabetes and insulin resistance in Chinese population.Gene. 2012 Nov 10;509(2):286-90. doi: 10.1016/j.gene.2012.07.086. Epub 2012 Aug 17.
563 Short-term exercise training reduces glycaemic variability and lowers circulating endothelial microparticles in overweight and obese women at elevated risk of type 2 diabetes.Eur J Sport Sci. 2019 Sep;19(8):1140-1149. doi: 10.1080/17461391.2019.1576772. Epub 2019 Feb 18.
564 Local Application of Semaphorin 3A Combined with Adipose-Derived Stem Cell Sheet and Anorganic Bovine Bone Granules Enhances Bone Regeneration in Type 2 Diabetes Mellitus Rats.Stem Cells Int. 2019 Jul 31;2019:2506463. doi: 10.1155/2019/2506463. eCollection 2019.
565 Effect of poor glycaemic control on plasma levels and activity of protein C, protein S, and antithrombin III in type 2 diabetes mellitus.PLoS One. 2019 Sep 27;14(9):e0223171. doi: 10.1371/journal.pone.0223171. eCollection 2019.
566 Identification of core genes and pathways in type 2 diabetes mellitus by bioinformatics analysis.Mol Med Rep. 2019 Sep;20(3):2597-2608. doi: 10.3892/mmr.2019.10522. Epub 2019 Jul 24.
567 Circulating miR-103 family as potential biomarkers for type 2 diabetes through targeting CAV-1 and SFRP4.Acta Diabetol. 2020 Mar;57(3):309-322. doi: 10.1007/s00592-019-01430-6. Epub 2019 Oct 3.
568 Regulatory mechanism of TGF-1/SGK1 pathway in tubulointerstitial fibrosis of diabetic nephropathy.Eur Rev Med Pharmacol Sci. 2019 Dec;23(23):10482-10488. doi: 10.26355/eurrev_201912_19687.
569 Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice.J Clin Invest. 2010 Dec;120(12):4316-31. doi: 10.1172/JCI41624. Epub 2010 Nov 15.
570 microRNA-141 is associated with hepatic steatosis by downregulating the sirtuin1/AMP-activated protein kinase pathway in hepatocytes.J Cell Physiol. 2020 Feb;235(2):880-890. doi: 10.1002/jcp.29002. Epub 2019 Jun 29.
571 SirT3 regulates diabetogenic effects caused by arsenic: An implication for mitochondrial complex II modification.Toxicol Lett. 2019 Feb;301:24-33. doi: 10.1016/j.toxlet.2018.10.025. Epub 2018 Oct 29.
572 Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs.Clin Epigenetics. 2019 Apr 15;11(1):63. doi: 10.1186/s13148-019-0660-y.
573 Associations of common variants in the SLC16A11, TCF7L2, and ABCA1 genes with pediatric-onset type 2 diabetes and related glycemic traits in families: A case-control and case-parent trio study.Pediatr Diabetes. 2017 Dec;18(8):824-831. doi: 10.1111/pedi.12497. Epub 2017 Jan 19.
574 Altered Glycemic Control Associated With Polymorphisms in the SLC22A1 (OCT1) Gene in a Mexican Population With Type 2 Diabetes Mellitus Treated With Metformin: A Cohort Study.J Clin Pharmacol. 2019 Oct;59(10):1384-1390. doi: 10.1002/jcph.1425. Epub 2019 Apr 23.
575 Genetic Modifiers of Cystic Fibrosis-Related Diabetes Have Extensive Overlap With Type 2 Diabetes and Related Traits.J Clin Endocrinol Metab. 2020 May 1;105(5):1401-15. doi: 10.1210/clinem/dgz102.
576 Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by SLC29A4) and Organic Cation Transporter 1 (OCT1) (Encoded by SLC22A1) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study.Diabetes Care. 2019 Jun;42(6):1027-1033. doi: 10.2337/dc18-2182. Epub 2019 Mar 18.
577 Protective role of adiponectin against testicular impairment in high-fat diet/streptozotocin-induced type 2 diabetic mice.Biochimie. 2020 Jan;168:41-52. doi: 10.1016/j.biochi.2019.10.014. Epub 2019 Oct 30.
578 Comparison of the urinary glucose excretion contributions of SGLT2 and SGLT1: A quantitative systems pharmacology analysis in healthy individuals and patients with type 2 diabetes treated with SGLT2 inhibitors.Diabetes Obes Metab. 2019 Dec;21(12):2684-2693. doi: 10.1111/dom.13858. Epub 2019 Sep 9.
579 Association of endothelial nitric oxide synthase (eNOS) and norepinephrine transporter (NET) genes polymorphism with type 2 diabetes mellitus.Mol Biol Rep. 2019 Oct;46(5):5433-5441. doi: 10.1007/s11033-019-04998-y. Epub 2019 Aug 3.
580 Contractility of ventricular myocytes is well preserved despite altered mechanisms of Ca2+ transport and a changing pattern of mRNA in aged type 2 Zucker diabetic fatty rat heart.Mol Cell Biochem. 2012 Feb;361(1-2):267-80. doi: 10.1007/s11010-011-1112-y. Epub 2011 Oct 19.
581 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.Diabetes. 2017 Nov;66(11):2888-2902. doi: 10.2337/db16-1253. Epub 2017 May 31.
582 Long-term moderate intensity exercise alleviates myocardial fibrosis in type 2 diabetic rats via inhibitions of oxidative stress and TGF-1/Smad pathway.J Physiol Sci. 2019 Nov;69(6):861-873. doi: 10.1007/s12576-019-00696-3. Epub 2019 Aug 7.
583 Acid Sphingomyelinase Down-regulation Alleviates Vascular Endothelial Insulin Resistance in Diabetic Rats.Basic Clin Pharmacol Toxicol. 2018 Dec;123(6):645-659. doi: 10.1111/bcpt.13073. Epub 2018 Jul 26.
584 Munc18b Increases Insulin Granule Fusion, Restoring Deficient Insulin Secretion in Type-2 Diabetes Human and Goto-Kakizaki Rat Islets with Improvement in Glucose Homeostasis.EBioMedicine. 2017 Feb;16:262-274. doi: 10.1016/j.ebiom.2017.01.030. Epub 2017 Jan 22.
585 Reducing effect of insulin resistance on alpha-synuclein gene expression in skeletal muscle.Diabetol Metab Syndr. 2019 Dec 2;11:99. doi: 10.1186/s13098-019-0499-6. eCollection 2019.
586 Sortilin levels are associated with peripheral arterial disease in type 2 diabetic subjects.Cardiovasc Diabetol. 2019 Jan 11;18(1):5. doi: 10.1186/s12933-019-0805-5.
587 Sphingosine kinase 1 regulates adipose proinflammatory responses and insulin resistance.Am J Physiol Endocrinol Metab. 2014 Apr 1;306(7):E756-68. doi: 10.1152/ajpendo.00549.2013. Epub 2014 Jan 28.
588 Adrenocortical insufficiency in Otsuka Long-Evans Tokushima Fatty rats, a type 2 diabetes mellitus model.Metabolism. 2007 Oct;56(10):1326-33. doi: 10.1016/j.metabol.2007.05.021.
589 Association study of SREBF-2 gene polymorphisms and the risk of type 2 diabetes in a sample of Iranian population.Gene. 2018 Jun 20;660:145-150. doi: 10.1016/j.gene.2018.03.080. Epub 2018 Mar 27.
590 Glycaemic target attainment in people with Type 2 diabetes treated with insulin glargine/lixisenatide fixed-ratio combination: a post hoc analysis of the LixiLan-O and LixiLan-L trials.Diabet Med. 2020 Feb;37(2):256-266. doi: 10.1111/dme.14094. Epub 2019 Nov 26.
591 Faster progression from MCI to probable AD for carriers of a single-nucleotide polymorphism associated with type 2 diabetes.Neurobiol Aging. 2018 Apr;64:157.e11-157.e17. doi: 10.1016/j.neurobiolaging.2017.11.013. Epub 2017 Dec 7.
592 STC-1 ameliorates renal injury in diabetic nephropathy by inhibiting the expression of BNIP3 through the AMPK/SIRT3 pathway.Lab Invest. 2019 May;99(5):684-697. doi: 10.1038/s41374-018-0176-7. Epub 2019 Jan 25.
593 Pros and cons of gastric bypass surgery in individuals with obesity and type 2 diabetes: nationwide, matched, observational cohort study.BMJ Open. 2019 Jan 15;9(1):e023882. doi: 10.1136/bmjopen-2018-023882.
594 Upregulation of proteins of the NLRP3 inflammasome in patients with periodontitis and uncontrolled type 2 diabetes.Oral Dis. 2019 Mar;25(2):596-608. doi: 10.1111/odi.13003. Epub 2018 Dec 16.
595 SULF2 strongly prediposes to fasting and postprandial triglycerides in patients with obesity and type 2 diabetes mellitus.Obesity (Silver Spring). 2014 May;22(5):1309-16. doi: 10.1002/oby.20682. Epub 2014 Jan 9.
596 Trace amine-associated receptor 1 (TAAR1) promotes anti-diabetic signaling in insulin-secreting cells.J Biol Chem. 2019 Mar 22;294(12):4401-4411. doi: 10.1074/jbc.RA118.005464. Epub 2019 Jan 22.
597 Inhibition of IKK and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes.Cell Metab. 2017 Jul 5;26(1):157-170.e7. doi: 10.1016/j.cmet.2017.06.006.
598 Classification of Clinically Diagnosed Alzheimer's Disease Associated with Diabetes Based on Amyloid and Tau PET Results.J Alzheimers Dis. 2019;71(1):261-271. doi: 10.3233/JAD-190620.
599 The variant at TGFBRAP1 is significantly associated with type 2 diabetes mellitus and affects diabetes-related miRNA expression.J Cell Mol Med. 2019 Jan;23(1):83-92. doi: 10.1111/jcmm.13885. Epub 2018 Nov 20.
600 Identification of autoimmune type 1 diabetes and multiple organ-specific autoantibodies in adult-onset non-insulin-requiring diabetes in China: A population-based multicentre nationwide survey.Diabetes Obes Metab. 2019 Apr;21(4):893-902. doi: 10.1111/dom.13595. Epub 2018 Dec 25.
601 Biomarkers of Vascular Injury and Type 2 Diabetes: A Prospective Study, Systematic Review and Meta-Analysis.J Clin Med. 2019 Nov 27;8(12):2075. doi: 10.3390/jcm8122075.
602 Common variants of genes encoding TLR4 and TLR4 pathway members TIRAP and IRAK1 are effective on MCP1, IL6, IL1, and TNF levels in type 2 diabetes and insulin resistance.Inflamm Res. 2019 Sep;68(9):801-814. doi: 10.1007/s00011-019-01263-7. Epub 2019 Jun 20.
603 Might genetics play a role in understanding and treating diabetic polyneuropathy?.Diabetes Metab Res Rev. 2017 May;33(4). doi: 10.1002/dmrr.2882. Epub 2017 Feb 23.
604 Toll-like receptors-2 and -9 (TLR2 and TLR9) gene polymorphism in patients with type 2 diabetes and diabetic foot.Medicine (Baltimore). 2017 Apr;96(17):e6760. doi: 10.1097/MD.0000000000006760.
605 Rare genetic diseases with human lean and/or starvation phenotype open new avenues for obesity and type II diabetes treatment.Curr Pharm Biotechnol. 2014;14(13):1093-8. doi: 10.2174/1389201015666140408124559.
606 Melatonin and Oxidative Stress in the Diabetic State: Clinical Implications and Potential Therapeutic Applications.Curr Med Chem. 2019;26(22):4178-4190. doi: 10.2174/0929867325666180410094149.
607 Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.Nat Commun. 2019 Feb 12;10(1):713. doi: 10.1038/s41467-019-08449-x.
608 Circulating TNF receptors and risk of renal disease progression, cardiovascular disease events and mortality in patients with diabetes: a systematic review and meta-analysis.Endocrine. 2020 Apr;68(1):32-43. doi: 10.1007/s12020-019-02153-y. Epub 2019 Dec 7.
609 Activation-Induced Cell Death of Mucosal-Associated Invariant T Cells Is Amplified by OX40 in Type 2 Diabetic Patients.J Immunol. 2019 Nov 15;203(10):2614-2620. doi: 10.4049/jimmunol.1900367. Epub 2019 Oct 2.
610 RANKL Gene Polymorphism as a Potential Biomarker to Identify Acute Charcot Foot Among Indian Population With Type 2 Diabetes: A Preliminary Report.Int J Low Extrem Wounds. 2019 Sep;18(3):287-293. doi: 10.1177/1534734619859730. Epub 2019 Jul 15.
611 Expression of TWEAK and its receptor Fn14 in human subcutaneous adipose tissue. Relationship with other inflammatory cytokines in obesity.Cytokine. 2006 Feb 7;33(3):129-37. doi: 10.1016/j.cyto.2005.12.005. Epub 2006 Feb 28.
612 Genome-wide association study identifies three novel loci for type 2 diabetes.Hum Mol Genet. 2014 Jan 1;23(1):239-46. doi: 10.1093/hmg/ddt399. Epub 2013 Aug 14.
613 Titration of insulin glargine 100U/mL when added to oral antidiabetic drugs in patients with type 2 diabetes: results of the TOP-1 real-world study.Acta Diabetol. 2020 Jan;57(1):89-99. doi: 10.1007/s00592-019-01383-w. Epub 2019 Jul 24.
614 Methylglyoxal and a spinal TRPA1-AC1-Epac cascade facilitate pain in the db/db mouse model of type 2 diabetes.Neurobiol Dis. 2019 Jul;127:76-86. doi: 10.1016/j.nbd.2019.02.019. Epub 2019 Feb 23.
615 The TRPC1 Ca(2+)-permeable channel inhibits exercise-induced protection against high-fat diet-induced obesity and type II diabetes.J Biol Chem. 2017 Dec 15;292(50):20799-20807. doi: 10.1074/jbc.M117.809954. Epub 2017 Oct 26.
616 Participation of the AngII/TRPC6/NFAT axis in the pathogenesis of podocyte injury in rats with type 2 diabetes.Mol Med Rep. 2019 Mar;19(3):2421-2430. doi: 10.3892/mmr.2019.9871. Epub 2019 Jan 17.
617 TRPM5 in the battle against diabetes and obesity. Acta Physiol (Oxf). 2018 Feb;222(2).
618 Potential Protective Mechanism in the Cardiac Microvascular Injury.Hypertension. 2018 Jul;72(1):116-127. doi: 10.1161/HYPERTENSIONAHA.118.11035. Epub 2018 May 7.
619 Association of serum prealbumin with risk of osteoporosis in older adults with type 2 diabetes mellitus: a cross-sectional study.Ther Adv Chronic Dis. 2019 Jun 13;10:2040622319857361. doi: 10.1177/2040622319857361. eCollection 2019.
620 Association of thioredoxin reductase 2 (TXNRD2) gene polymorphisms with myocardial infarction in Slovene patients with type 2 diabetes mellitus.Diabetes Res Clin Pract. 2015 May;108(2):323-8. doi: 10.1016/j.diabres.2015.01.038. Epub 2015 Feb 7.
621 UCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in -cells: evidence of interplay between the ubiquitin/proteasome system and autophagy.Autophagy. 2014 Jun;10(6):1004-14. doi: 10.4161/auto.28478.
622 Allicin induces beige-like adipocytes via KLF15 signal cascade.J Nutr Biochem. 2019 Feb;64:13-24. doi: 10.1016/j.jnutbio.2018.09.014. Epub 2018 Sep 23.
623 Serum bilirubin concentration is modified by UGT1A1 haplotypes and influences risk of type-2 diabetes in the Norfolk Island genetic isolate.BMC Genet. 2015 Dec 2;16:136. doi: 10.1186/s12863-015-0291-z.
624 The Association of UNC13B Gene Polymorphisms and Diabetic Kidney Disease in a Chinese Han Population.Med Sci Monit. 2019 Nov 12;25:8527-8533. doi: 10.12659/MSM.919930.
625 Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14.Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21732-21738. doi: 10.1073/pnas.1907288116. Epub 2019 Oct 8.
626 Efficacy and safety of dapagliflozin as monotherapy in patients with type 2 diabetes mellitus: A meta-analysis of randomized controlled trials.Medicine (Baltimore). 2019 Jul;98(30):e16575. doi: 10.1097/MD.0000000000016575.
627 The SNP rs9677 of VPAC1 gene is associated with glycolipid control and heart function in female patients with type 2 diabetes: A follow-up study.Nutr Metab Cardiovasc Dis. 2016 Feb;26(2):109-13. doi: 10.1016/j.numecd.2015.10.009. Epub 2015 Oct 30.
628 Reduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitus.Circulation. 2008 May 27;117(21):2785-92. doi: 10.1161/CIRCULATIONAHA.107.741314. Epub 2008 May 19.
629 Current therapies and targets for type 2 diabetes mellitus.Panminerva Med. 2018 Sep;60(3):117-131. doi: 10.23736/S0031-0808.18.03455-9. Epub 2018 Apr 24.
630 AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY 2018 POSITION STATEMENT ON INTEGRATION OF INSULIN PUMPS AND CONTINUOUS GLUCOSE MONITORING IN PATIENTS WITH DIABETES MELLITUS.Endocr Pract. 2018 Mar;24(3):302-308. doi: 10.4158/PS-2017-0155.
631 INCREASED BONE TURNOVER IN TYPE 2 DIABETES PATIENTS RANDOMIZED TO BARIATRIC SURGERY VERSUS MEDICAL THERAPY AT 5 YEARS.Endocr Pract. 2018 Mar;24(3):256-264. doi: 10.4158/EP-2017-0072. Epub 2017 Nov 16.
632 Tat-biliverdin reductase A protects INS-1 cells from human islet amyloid polypeptide-induced cytotoxicity by alleviating oxidative stress and ER stress.Cell Biol Int. 2017 May;41(5):514-524. doi: 10.1002/cbin.10750. Epub 2017 Mar 20.
633 A novel role of bone morphogenetic protein 6 (BMP6) in glucose homeostasis.Acta Diabetol. 2019 Mar;56(3):365-371. doi: 10.1007/s00592-018-1265-1. Epub 2018 Dec 11.
634 The co-activator-associated arginine methyltransferase 1 (CARM1) gene is overexpressed in type 2 diabetes.Endocrine. 2019 Feb;63(2):284-292. doi: 10.1007/s12020-018-1740-z. Epub 2018 Sep 1.
635 Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin. J Clin Endocrinol Metab. 2004 Nov;89(11):5535-41.
636 Chimerin 2 genetic polymorphisms are associated with non-proliferative diabetic retinopathy in Taiwanese type 2 diabetic patients.J Diabetes Complications. 2014 Jul-Aug;28(4):460-3. doi: 10.1016/j.jdiacomp.2014.04.009. Epub 2014 Apr 18.
637 Chemerin induces endothelial cell inflammation: activation of nuclear factor-kappa beta and monocyte-endothelial adhesion.Oncotarget. 2018 Mar 30;9(24):16678-16690. doi: 10.18632/oncotarget.24659. eCollection 2018 Mar 30.
638 Gene expression profiles of rat MMECs with different glucose levels and fgl2 gene silencing.Diabetes Metab Res Rev. 2018 Nov;34(8):e3058. doi: 10.1002/dmrr.3058. Epub 2018 Sep 13.
639 Testing an association between TLR4 and CXCR1 gene polymorphisms with susceptibility to urinary tract infection in type 2 diabetes in north Indian population.Gene. 2018 Jan 30;641:196-202. doi: 10.1016/j.gene.2017.10.060. Epub 2017 Oct 21.
640 PF-04620110, a Potent Antidiabetic Agent, Suppresses Fatty Acid-Induced NLRP3 Inflammasome Activation in Macrophages.Diabetes Metab J. 2019 Oct;43(5):683-699. doi: 10.4093/dmj.2019.0112.
641 A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women.PLoS One. 2017 Mar 2;12(3):e0172577. doi: 10.1371/journal.pone.0172577. eCollection 2017.
642 TERT and Akt Are Involved in the Par-4-Dependent Apoptosis of Islet Cells in Type 2 Diabetes.J Diabetes Res. 2018 Aug 14;2018:7653904. doi: 10.1155/2018/7653904. eCollection 2018.
643 Transcriptomic analysis of Momordica charantia polysaccharide on streptozotocin-induced diabetic rats.Gene. 2018 Oct 30;675:208-216. doi: 10.1016/j.gene.2018.06.106. Epub 2018 Jul 4.
644 The beneficial effects of Lactobacillus reuteri ADR-1 or ADR-3 consumption on type 2 diabetes mellitus: a randomized, double-blinded, placebo-controlled trial.Sci Rep. 2018 Nov 14;8(1):16791. doi: 10.1038/s41598-018-35014-1.
645 Cardioprotective and anti-inflammatory effects of G-protein coupled receptor 30 (GPR30) on postmenopausal type 2 diabetic rats.Biomed Pharmacother. 2018 Dec;108:153-164. doi: 10.1016/j.biopha.2018.09.028. Epub 2018 Sep 13.
646 Elevated Levels of Serum 2-Glycoprotein I/Oxidized Low-Density Lipoprotein Complexes Are Associated with Cerebral Infarction in Patients with Type 2 Diabetes Mellitus.Med Sci Monit. 2018 Feb 28;24:1232-1240. doi: 10.12659/msm.907078.
647 Prioritizing candidate disease genes by network-based boosting of genome-wide association data.Genome Res. 2011 Jul;21(7):1109-21. doi: 10.1101/gr.118992.110. Epub 2011 May 2.
648 G protein-coupled receptor kinase 2 (GRK2) as an integrative signalling node in the regulation of cardiovascular function and metabolic homeostasis.Cell Signal. 2018 Jan;41:25-32. doi: 10.1016/j.cellsig.2017.04.002. Epub 2017 Apr 4.
649 Long Noncoding RNA lncSHGL Recruits hnRNPA1 to Suppress Hepatic Gluconeogenesis and Lipogenesis.Diabetes. 2018 Apr;67(4):581-593. doi: 10.2337/db17-0799. Epub 2018 Jan 30.
650 Hoxa5 Promotes Adipose Differentiation via Increasing DNA Methylation Level and Inhibiting PKA/HSL Signal Pathway in Mice.Cell Physiol Biochem. 2018;45(3):1023-1033. doi: 10.1159/000487343. Epub 2018 Feb 7.
651 Serum IL-15 and IL-15R levels are decreased in lean and obese physically active humans.Scand J Med Sci Sports. 2018 Mar;28(3):1113-1120. doi: 10.1111/sms.12983. Epub 2017 Oct 16.
652 Association of IL-16 gene polymorphisms with the risk of developing type 2 diabetes mellitus in the Chinese Han population.Biosci Rep. 2019 Aug 15;39(8):BSR20190821. doi: 10.1042/BSR20190821. Print 2019 Aug 30.
653 Interaction of iron status with single nucleotide polymorphisms on incidence of type 2 diabetes.PLoS One. 2017 Apr 13;12(4):e0175681. doi: 10.1371/journal.pone.0175681. eCollection 2017.
654 Modulation of insulin receptor signalling: significance of altered receptor isoform patterns and mechanism of hyperglycaemia-induced receptor modulation.Diabetologia. 1994 Sep;37 Suppl 2:S149-54. doi: 10.1007/BF00400838.
655 Metformin regulates atrial SK2 and SK3 expression through inhibiting the PKC/ERK signaling pathway in type 2 diabetic rats.BMC Cardiovasc Disord. 2018 Dec 13;18(1):236. doi: 10.1186/s12872-018-0950-x.
656 Placental protein expression of kisspeptin-1 (KISS1) and the kisspeptin-1 receptor (KISS1R) in pregnancy complicated by diabetes mellitus or preeclampsia.Arch Gynecol Obstet. 2020 Feb;301(2):437-445. doi: 10.1007/s00404-019-05408-1. Epub 2019 Dec 6.
657 Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats.Mol Neurobiol. 2018 May;55(5):4030-4050. doi: 10.1007/s12035-017-0622-3. Epub 2017 Jun 2.
658 Evidence for the link between defective autophagy and inflammation in peripheral blood mononuclear cells of type 2 diabetic patients.J Physiol Biochem. 2018 Aug;74(3):369-379. doi: 10.1007/s13105-018-0624-2. Epub 2018 Apr 13.
659 Type 2 diabetes with hypertensive patients results in changes to features of adipocytokines: Leptin, Irisin, LGR4, and Sfrp5.Clin Exp Hypertens. 2019;41(7):645-650. doi: 10.1080/10641963.2018.1529779. Epub 2018 Oct 11.
660 Circulating C1q complement/TNF-related protein (CTRP) 1, CTRP9, CTRP12 and CTRP13 concentrations in Type 2 diabetes mellitus: In vivo regulation by glucose.PLoS One. 2017 Feb 16;12(2):e0172271. doi: 10.1371/journal.pone.0172271. eCollection 2017.
661 LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro.Diabetologia. 2016 Oct;59(10):2134-44. doi: 10.1007/s00125-016-4036-y. Epub 2016 Jul 15.
662 MAP4K4 and IL-6(+) Th17 cells play important roles in non-obese type 2 diabetes.J Biomed Sci. 2017 Jan 7;24(1):4. doi: 10.1186/s12929-016-0307-7.
663 High Mannose-Binding Lectin Serum Levels Are Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes.PLoS One. 2015 Jul 2;10(7):e0130665. doi: 10.1371/journal.pone.0130665. eCollection 2015.
664 Efficacy and safety of methionine aminopeptidase 2 inhibition in type 2 diabetes: a randomised, placebo-controlled clinical trial.Diabetologia. 2018 Sep;61(9):1918-1922. doi: 10.1007/s00125-018-4677-0. Epub 2018 Jul 11.
665 Identification of BR101549 as a lead candidate of non-TZD PPAR agonist for the treatment of type 2 diabetes: Proof-of-concept evaluation and SAR.Bioorg Med Chem Lett. 2019 Feb 15;29(4):631-637. doi: 10.1016/j.bmcl.2018.12.043. Epub 2018 Dec 19.
666 Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization.Sci Rep. 2017 Feb 21;7:42880. doi: 10.1038/srep42880.
667 Exploring the insulin secretory properties of the PGD2-GPR44/DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients.PLoS One. 2018 Dec 17;13(12):e0208998. doi: 10.1371/journal.pone.0208998. eCollection 2018.
668 Effects of prolonged type 2 diabetes on mitochondrial function in cerebral blood vessels.Am J Physiol Heart Circ Physiol. 2019 Nov 1;317(5):H1086-H1092. doi: 10.1152/ajpheart.00341.2019. Epub 2019 Sep 6.
669 Urine proteome analysis by C18 plate-matrix-assisted laser desorption/ionization time-of-flight mass spectrometry allows noninvasive differential diagnosis and prediction of diabetic nephropathy.PLoS One. 2018 Jul 19;13(7):e0200945. doi: 10.1371/journal.pone.0200945. eCollection 2018.
670 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.Diabetes. 2013 May;62(5):1746-55. doi: 10.2337/db12-1077. Epub 2013 Jan 8.
671 Adenovirus-mediated expression of SIK1 improves hepatic glucose and lipid metabolism in type 2 diabetes mellitus rats.PLoS One. 2019 Jun 24;14(6):e0210930. doi: 10.1371/journal.pone.0210930. eCollection 2019.
672 Functional genetic variants within the SIRT2 gene promoter in type 2 diabetes mellitus.Diabetes Res Clin Pract. 2018 Mar;137:200-207. doi: 10.1016/j.diabres.2018.01.012. Epub 2018 Jan 31.
673 Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial.BMC Gastroenterol. 2018 Jan 5;18(1):3. doi: 10.1186/s12876-017-0736-0.
674 Increased Small Intestine Expression of Non-Heme Iron Transporters in Morbidly Obese Patients With Newly Diagnosed Type 2 Diabetes.Mol Nutr Food Res. 2018 Jan;62(2). doi: 10.1002/mnfr.201700301. Epub 2017 Dec 29.
675 Na(+) /H(+) exchanger 3 blockade ameliorates type 2 diabetes mellitus via inhibition of sodium-glucose co-transporter 1-mediated glucose absorption in the small intestine.Diabetes Obes Metab. 2018 Mar;20(3):709-717. doi: 10.1111/dom.13151. Epub 2017 Dec 5.
676 Structural insights into suppressor of cytokine signaling 1 protein- identification of new leads for type 2 diabetes mellitus.J Mol Recognit. 2018 Jul;31(7):e2706. doi: 10.1002/jmr.2706. Epub 2018 Apr 6.
677 Increased serotransferrin and ceruloplasmin turnover in diet-controlled patients with type 2 diabetes.Free Radic Biol Med. 2017 Dec;113:461-469. doi: 10.1016/j.freeradbiomed.2017.10.373. Epub 2017 Oct 25.
678 Perspectives of Patients with Insulin-Treated Type 1 and Type 2 Diabetes on Hypoglycemia: Results of the HAT Observational Study in Central and Eastern European Countries.Diabetes Ther. 2018 Apr;9(2):727-741. doi: 10.1007/s13300-018-0388-2. Epub 2018 Mar 9.
679 Association between severity of obstructive sleep apnea and glycated hemoglobin level in Japanese individuals with and without diabetes.Endocr J. 2018 Jan 30;65(1):121-127. doi: 10.1507/endocrj.EJ17-0356. Epub 2017 Sep 20.
680 Serum Glutaredoxin Activity as a Marker of Oxidative Stress in Chronic Kidney Disease: A Pilot Study.Nephron. 2018;140(4):249-256. doi: 10.1159/000492500. Epub 2018 Sep 25.
681 Silymarin ameliorates expression of urotensin II (U-II) and its receptor (UTR) and attenuates toxic oxidative stress in the heart of rats with type 2 diabetes.Biomed Pharmacother. 2018 May;101:244-250. doi: 10.1016/j.biopha.2018.02.075. Epub 2018 Feb 27.
682 Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in Cells.Cell Metab. 2019 Jan 8;29(1):64-77.e6. doi: 10.1016/j.cmet.2018.09.008. Epub 2018 Oct 4.
683 WRN gene 1367 Arg allele protects against development of type 2 diabetes mellitus.Diabetes Res Clin Pract. 2005 Sep;69(3):287-92. doi: 10.1016/j.diabres.2005.01.012. Epub 2005 Mar 16.
684 Seasonal Variations in the Achievement of Guideline Targets for HbA(1c), Blood Pressure, and Cholesterol Among Patients With Type 2 Diabetes: A Nationwide Population-Based Study (ABC Study: JDDM49).Diabetes Care. 2019 May;42(5):816-823. doi: 10.2337/dc18-1953. Epub 2019 Feb 10.
685 Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet. 2003 Feb;33(2):177-82. doi: 10.1038/ng1071. Epub 2003 Jan 13.
686 Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study.PLoS One. 2011;6(8):e24052. doi: 10.1371/journal.pone.0024052. Epub 2011 Aug 25.
687 Major urinary protein regulation of chemical communication and nutrient metabolism.Vitam Horm. 2010;83:151-63. doi: 10.1016/S0083-6729(10)83006-7.
688 The expression of particular glucose transporters and insulin resistance indicators in the risk groups of type 2 diabetes--a two-year follow-up.Endokrynol Pol. 2012;63(3):212-9.
689 Zinc transporter gene expression and glycemic control in post-menopausal women with Type 2 diabetes mellitus.J Trace Elem Med Biol. 2014 Oct;28(4):448-52. doi: 10.1016/j.jtemb.2014.07.012. Epub 2014 Aug 2.
690 Circulating levels of cortistatin are correlated with metabolic parameters in patients with newly diagnosed type 2 diabetes mellitus.Peptides. 2017 Aug;94:86-90. doi: 10.1016/j.peptides.2017.05.008. Epub 2017 May 17.
691 Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium.Diabetes. 2015 May;64(5):1853-66. doi: 10.2337/db14-0732. Epub 2014 Dec 18.
692 Targeting the Zinc Transporter ZIP7 in the Treatment of Insulin Resistance and Type 2 Diabetes.Nutrients. 2019 Feb 15;11(2):408. doi: 10.3390/nu11020408.
693 Genetic variations in magnesium-related ion channels may affect diabetes risk among African American and Hispanic American women.J Nutr. 2015 Mar;145(3):418-24. doi: 10.3945/jn.114.203489. Epub 2015 Jan 7.
694 The ratios of pro-inflammatory to anti-inflammatory cytokines in the serum of chronic periodontitis patients with and without type 2 diabetes and/or smoking habit.Clin Oral Investig. 2019 Feb;23(2):641-650. doi: 10.1007/s00784-018-2471-5. Epub 2018 May 8.
695 Akt2 (Protein Kinase B Beta) Stabilizes ATP7A, a Copper Transporter for Extracellular Superoxide Dismutase, in Vascular Smooth Muscle: Novel Mechanism to Limit Endothelial Dysfunction in Type 2 Diabetes Mellitus.Arterioscler Thromb Vasc Biol. 2018 Mar;38(3):529-541. doi: 10.1161/ATVBAHA.117.309819. Epub 2018 Jan 4.
696 Association of VEGF and eNOS gene polymorphisms in type 2 diabetic retinopathy.Mol Vis. 2006 Apr 11;12:336-41.
697 Influence of antioxidants' gene variants on risk of diabetes mellitus and its complications: a systematic review.Minerva Endocrinol. 2019 Sep;44(3):310-325. doi: 10.23736/S0391-1977.17.02632-3. Epub 2017 May 26.
698 Predictive significance of kidney myeloid-related protein 8 expression in patients with obesity- or type 2 diabetes-associated kidney diseases.PLoS One. 2014 Feb 18;9(2):e88942. doi: 10.1371/journal.pone.0088942. eCollection 2014.
699 Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP-1.Obesity (Silver Spring). 2019 Aug;27(8):1292-1304. doi: 10.1002/oby.22521.
700 ATP2B1 gene Silencing Increases Insulin Sensitivity through Facilitating Akt Activation via the Ca(2+)/calmodulin Signaling Pathway and Ca(2+)-associated eNOS Activation in Endothelial Cells.Int J Biol Sci. 2017 Sep 5;13(9):1203-1212. doi: 10.7150/ijbs.19666. eCollection 2017.
701 Evolutionary history of disease-susceptibility loci identified in longitudinal exome-wide association studies.Mol Genet Genomic Med. 2019 Sep;7(9):e925. doi: 10.1002/mgg3.925. Epub 2019 Aug 11.
702 Suo Quan Wan Protects Mouse From Early Diabetic Bladder Dysfunction by Mediating Motor Protein Myosin Va and Transporter Protein SLC17A9.Front Pharmacol. 2019 May 24;10:552. doi: 10.3389/fphar.2019.00552. eCollection 2019.
703 Fatty Acid Metabolites Combine with Reduced Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes.Cell Metab. 2019 Sep 3;30(3):447-461.e5. doi: 10.1016/j.cmet.2019.07.004. Epub 2019 Aug 1.
704 Antisense Inhibition of Protein Tyrosine Phosphatase 1B With IONIS-PTP-1B(Rx) Improves Insulin Sensitivity and Reduces Weight in Overweight Patients With Type 2 Diabetes.Diabetes Care. 2018 Apr;41(4):807-814. doi: 10.2337/dc17-2132. Epub 2018 Feb 9.
705 Identification of the fructose transporter GLUT5 (SLC2A5) as a novel target of nuclear receptor LXR.Sci Rep. 2019 Jun 26;9(1):9299. doi: 10.1038/s41598-019-45803-x.
706 Gingival crevicular fluid levels of protease-activated receptors type 1 and type 2 in diabetic patients with periodontitis.J Periodontal Res. 2016 Oct;51(5):577-85. doi: 10.1111/jre.12336. Epub 2015 Nov 13.
707 A genetic variant in SLC6A20 is associated with Type 2 diabetes in white-European and Chinese populations. Diabet Med. 2014 Nov;31(11):1350-6.
708 Amiloride-sensitive Na+/H+ exchange in erythrocytes of patients with NIDDM: a prospective study.Diabetologia. 1997 Mar;40(3):302-6. doi: 10.1007/s001250050678.
709 Differential effects of type 2 diabetes on brain glycometabolism in rats: focus on glycogen and monocarboxylate transporter 2.J Physiol Sci. 2018 Jan;68(1):69-75. doi: 10.1007/s12576-016-0508-6. Epub 2016 Dec 16.
710 Sensors for measuring subcellular zinc pools.Metallomics. 2018 Feb 21;10(2):229-239. doi: 10.1039/c7mt00336f.
711 Alcohol consumption and type 2 diabetes: influence of genetic variation in alcohol dehydrogenase.Diabetes. 2007 Sep;56(9):2388-94. doi: 10.2337/db07-0181. Epub 2007 Jun 11.
712 Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis.J Mol Med (Berl). 2012 Jul;90(7):847-58. doi: 10.1007/s00109-012-0898-8. Epub 2012 Apr 15.
713 11Beta-hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics.Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6734-9. doi: 10.1073/pnas.0306996101. Epub 2004 Apr 7.
714 Whole exome sequencing identifies variation in CYB5A and RNF10 associated with adiposity and type 2 diabetes.Obesity (Silver Spring). 2014 Apr;22(4):984-8. doi: 10.1002/oby.20647. Epub 2013 Dec 5.
715 Correlation between the decrease of cholesterol efflux from macrophages in patients with type II diabetes mellitus and down-regulated CYP7A1 expression.Genet Mol Res. 2015 Jul 31;14(3):8716-24. doi: 10.4238/2015.July.31.20.
716 Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes.BMC Med Genet. 2011 Jul 25;12:99. doi: 10.1186/1471-2350-12-99.
717 The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: the DAMAGE study.Diabetes. 2006 Nov;55(11):3193-6. doi: 10.2337/db06-0414.
718 Alterations in hepatic metabolism of sulfur amino acids in non-obese type-2 diabetic Goto-Kakizaki rats.Chem Biol Interact. 2013 Jul 5;204(2):80-7. doi: 10.1016/j.cbi.2013.04.014. Epub 2013 May 9.
719 Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes.PLoS Genet. 2010 May 6;6(5):e1000932. doi: 10.1371/journal.pgen.1000932.
720 Alterations in nitric oxide/cyclic-GMP pathway in nondiabetic siblings of patients with type 2 diabetes.J Clin Endocrinol Metab. 2000 Jul;85(7):2416-20. doi: 10.1210/jcem.85.7.6667.
721 Bilirubin as a potential causal factor in type 2 diabetes risk: a Mendelian randomization study.Diabetes. 2015 Apr;64(4):1459-69. doi: 10.2337/db14-0228. Epub 2014 Nov 3.
722 Is there a genetic basis for gestational diabetes?.Hum Biol. 1994 Aug;66(4):715-23.
723 Bioactives of Artemisia dracunculus L enhance cellular insulin signaling in primary human skeletal muscle culture.Metabolism. 2008 Jul;57(7 Suppl 1):S58-64. doi: 10.1016/j.metabol.2008.04.003.
724 Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes.Circ Res. 2020 Jan 31;126(3):330-346. doi: 10.1161/CIRCRESAHA.119.315246. Epub 2019 Nov 19.
725 Assessment of erectile dysfunction and associated psychological distress in Chinese men with type 2 diabetes mellitus.Int J Impot Res. 2017 Sep;29(5):210-214. doi: 10.1038/ijir.2017.25. Epub 2017 Jun 29.
726 Estrogen sulfotransferase in the metabolism of estrogenic drugs and in the pathogenesis of diseases.Expert Opin Drug Metab Toxicol. 2019 Apr;15(4):329-339. doi: 10.1080/17425255.2019.1588884. Epub 2019 Mar 18.
727 Classification of Genes: Standardized Clinical Validity Assessment of Gene-Disease Associations Aids Diagnostic Exome Analysis and Reclassifications. Hum Mutat. 2017 May;38(5):600-608. doi: 10.1002/humu.23183. Epub 2017 Feb 13.
728 "DAK", a traditional decoction in Palau, as adjuvant for patients with insufficient control of diabetes mellitus type II.J Ethnopharmacol. 2017 Jun 9;205:116-122. doi: 10.1016/j.jep.2017.05.003. Epub 2017 May 3.
729 Restraining PI3K: mTOR signalling goes back to the membrane.Trends Biochem Sci. 2005 Jan;30(1):35-42. doi: 10.1016/j.tibs.2004.11.003.
730 Coronary Heart Disease and ABO Blood Group in Diabetic Women: A Case-Control Study.Sci Rep. 2019 May 15;9(1):7441. doi: 10.1038/s41598-019-43890-4.
731 The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment.Metabolism. 2006 Oct;55(10):1411-9. doi: 10.1016/j.metabol.2006.06.013.
732 ALDH2/ADH2 polymorphism associated with vasculopathy and neuropathy in type 2 diabetes.Alcohol Clin Exp Res. 2004 Aug;28(8 Suppl Proceedings):111S-116S. doi: 10.1097/01.alc.0000133583.44581.99.
733 Type 2 diabetes and metabolic syndrome - adipokine levels and effect of drugs.Gynecol Endocrinol. 2017 Jan;33(1):75-78. doi: 10.1080/09513590.2016.1207165. Epub 2016 Oct 5.
734 BMP and mTOR signaling in heterotopic ossification: Does their crosstalk provide therapeutic opportunities?.J Cell Biochem. 2019 Aug;120(8):12108-12122. doi: 10.1002/jcb.28710. Epub 2019 Apr 15.
735 Sterol 27-Hydroxylase Polymorphism Significantly Associates With Shorter Telomere, Higher Cardiovascular and Type-2 Diabetes Risk in Obese Subjects.Front Endocrinol (Lausanne). 2018 Jun 13;9:309. doi: 10.3389/fendo.2018.00309. eCollection 2018.
736 Distribution of CYP2C8 and CYP2C9 amino acid substitution alleles in South Indian diabetes patients: A genotypic and computational protein phenotype study.Clin Exp Pharmacol Physiol. 2017 Dec;44(12):1171-1179. doi: 10.1111/1440-1681.12810. Epub 2017 Sep 20.
737 Triangular relationship between CYP2R1 gene polymorphism, serum 25(OH)D(3) levels and T2DM in a Chinese rural population.Gene. 2018 Dec 15;678:172-176. doi: 10.1016/j.gene.2018.08.006. Epub 2018 Aug 4.
738 DDAH1 promoter -396 4N insertion variant is associated with increased risk of type 2 diabetes in a gender-dependent manner.Mol Genet Genomic Med. 2020 Jan;8(1):e1011. doi: 10.1002/mgg3.1011. Epub 2019 Nov 16.
739 A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness).Diabetologia. 2014 Jun;57(6):1159-72. doi: 10.1007/s00125-014-3215-y. Epub 2014 Mar 25.
740 The Association of Polyunsaturated Fatty Acid -5-Desaturase Activity with Risk Factors for Type 2 Diabetes Is Dependent on Plasma ApoB-Lipoproteins in Overweight and Obese Adults.J Nutr. 2019 Jan 1;149(1):57-67. doi: 10.1093/jn/nxy238.
741 Vitamin D receptor gene polymorphisms among Emirati patients with type 2 diabetes mellitus.J Steroid Biochem Mol Biol. 2018 Jan;175:119-124. doi: 10.1016/j.jsbmb.2017.03.012. Epub 2017 Mar 18.
742 In Silico Preliminary Association of Ammonia Metabolism Genes GLS, CPS1, and GLUL with Risk of Alzheimer's Disease, Major Depressive Disorder, and Type 2 Diabetes.J Mol Neurosci. 2018 Mar;64(3):385-396. doi: 10.1007/s12031-018-1035-0. Epub 2018 Feb 13.
743 Identification of novel genetic variants for type 2 diabetes, childhood obesity, and their pleiotropic loci.J Hum Genet. 2019 May;64(5):369-377. doi: 10.1038/s10038-019-0577-5. Epub 2019 Feb 28.
744 Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction.Diabetes. 2010 May;59(5):1132-42. doi: 10.2337/db09-1105. Epub 2010 Feb 11.
745 A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders.Sci Rep. 2018 Feb 26;8(1):3660. doi: 10.1038/s41598-018-22081-7.
746 Association of HNF4 gene polymorphisms with susceptibility to type 2 diabetes.Mol Med Rep. 2016 Mar;13(3):2241-6. doi: 10.3892/mmr.2016.4780. Epub 2016 Jan 13.
747 A model-based approach to analyze the influence of UGT2B15 polymorphism driven pharmacokinetic differences on the pharmacodynamic response of the PPAR agonist sipoglitazar.J Clin Pharmacol. 2014 Apr;54(4):453-61. doi: 10.1002/jcph.227. Epub 2013 Nov 20.
748 THE MANAGEMENT OF HYPERGLYCEMIA IN NONCRITICALLY ILL HOSPITALIZED PATIENTS TREATED WITH CONTINUOUS ENTERAL OR PARENTERAL NUTRITION.Endocr Pract. 2018 Oct 2;24(10):900-906. doi: 10.4158/EP-2018-0150. Epub 2018 Jul 23.
749 Rethinking Bile Acid Metabolism and Signaling for Type 2 Diabetes Treatment.Curr Diab Rep. 2018 Sep 19;18(11):109. doi: 10.1007/s11892-018-1092-3.
750 Structure-function relationship in early diabetic retinopathy: a spatial correlation analysis with OCT and microperimetry.Eye (Lond). 2017 Jun;31(6):931-939. doi: 10.1038/eye.2017.27. Epub 2017 Mar 3.
751 Glutamine fructose-6-phosphate amidotransferase (GFAT) gene expression and activity in patients with type 2 diabetes: inter-relationships with hyperglycaemia and oxidative stress.Clin Biochem. 2007 Sep;40(13-14):952-7. doi: 10.1016/j.clinbiochem.2007.05.002. Epub 2007 May 24.
752 Plasma ferritin, C-reactive protein, and risk of incident type 2 diabetes in Singapore Chinese men and women.Diabetes Res Clin Pract. 2017 Jun;128:109-118. doi: 10.1016/j.diabres.2017.04.012. Epub 2017 Apr 13.
753 Allele-specific targeting of hsa-miR-657 to human IGF2R creates a potential mechanism underlying the association of ACAA-insertion/deletion polymorphism with type 2 diabetes.Biochem Biophys Res Commun. 2008 Sep 12;374(1):101-5. doi: 10.1016/j.bbrc.2008.06.102. Epub 2008 Jul 9.
754 New susceptibility locus for NIDDM is localized to human chromosome 20q.Diabetes. 1997 May;46(5):876-81. doi: 10.2337/diab.46.5.876.
755 The alpha-adducin gene is associated with macrovascular complications and mortality in patients with type 2 diabetes.Diabetes. 2006 Oct;55(10):2922-7. doi: 10.2337/db06-0302.
756 CNV Analysis Associates AKNAD1 with Type-2 Diabetes in Jordan Subpopulations.Sci Rep. 2015 Aug 21;5:13391. doi: 10.1038/srep13391.
757 Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss.Diabetologia. 2014 Nov;57(11):2384-92. doi: 10.1007/s00125-014-3347-0. Epub 2014 Aug 7.
758 Reduced skeletal muscle phosphocreatine concentration in type 2 diabetic patients: a quantitative image-based phosphorus-31 MR spectroscopy study.Am J Physiol Endocrinol Metab. 2018 Aug 1;315(2):E229-E239. doi: 10.1152/ajpendo.00426.2017. Epub 2018 Mar 6.
759 Metallothionein-mediated antioxidant defense system and its response to exercise training are impaired in human type 2 diabetes.Diabetes. 2005 Nov;54(11):3089-94. doi: 10.2337/diabetes.54.11.3089.
760 ALMS1 and Alstrm syndrome: a recessive form of metabolic, neurosensory and cardiac deficits.J Mol Med (Berl). 2019 Jan;97(1):1-17. doi: 10.1007/s00109-018-1714-x. Epub 2018 Nov 12.
761 Anti-Mllerian hormone in type 2 and gestational diabetes during the second half of pregnancy: relationship with sexual steroid levels and metabolic parameters.Gynecol Endocrinol. 2018 Feb;34(2):120-124. doi: 10.1080/09513590.2017.1359824. Epub 2017 Jul 31.
762 Ankyrin-B metabolic syndrome combines age-dependent adiposity with pancreatic cell insufficiency.J Clin Invest. 2015 Aug 3;125(8):3087-102. doi: 10.1172/JCI81317. Epub 2015 Jul 13.
763 Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility.Diabet Med. 2014 Aug;31(8):1001-8. doi: 10.1111/dme.12464. Epub 2014 May 2.
764 Genetic basis of dyslipidemia in disease precipitation of coronary artery disease (CAD) associated type 2 diabetes mellitus (T2DM).Diabetes Metab Res Rev. 2015 Oct;31(7):663-71. doi: 10.1002/dmrr.2630. Epub 2015 Mar 5.
765 Genetic variability in adapter proteins with APPL1/2 is associated with the risk of coronary artery disease in type 2 diabetes mellitus in Chinese Han population.Chin Med J (Engl). 2011 Nov;124(22):3618-21.
766 Genetic predisposition and nongenetic risk factors of thiazolidinedione-related edema in patients with type 2 diabetes.Pharmacogenet Genomics. 2011 Dec;21(12):829-36. doi: 10.1097/FPC.0b013e32834bfff1.
767 ARC is essential for maintaining pancreatic islet structure and -cell viability during type 2 diabetes.Sci Rep. 2017 Aug 1;7(1):7019. doi: 10.1038/s41598-017-07107-w.
768 Relationship between Modulator Recognition Factor 2/AT-rich Interaction Domain 5B Gene Variations and Type 2 Diabetes Mellitus or Lipid Metabolism in a Northern Chinese Population.Chin Med J (Engl). 2017 May 5;130(9):1055-1061. doi: 10.4103/0366-6999.204926.
769 Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins.PLoS One. 2009;4(3):e4793. doi: 10.1371/journal.pone.0004793. Epub 2009 Mar 10.
770 An aminophospholipid translocase associated with body fat and type 2 diabetes phenotypes.Obes Res. 2002 Jul;10(7):695-702. doi: 10.1038/oby.2002.94.
771 Association between RBMS1 gene rs7593730 and BCAR1 gene rs7202877 and Type 2 diabetes mellitus in the Chinese Han population.Acta Biochim Pol. 2018;65(3):377-382. doi: 10.18388/abp.2017_1451. Epub 2018 Sep 8.
772 -Glucosidase inhibitory activity of protein-rich extracts from extruded adzuki bean in diabetic KK-Ay mice.Food Funct. 2014 May;5(5):966-71. doi: 10.1039/c3fo60521c.
773 Potential contribution of the Alzheimer's disease risk locus BIN1 to episodic memory performance in cognitively normal Type 2 diabetes elderly.Eur Neuropsychopharmacol. 2016 Apr;26(4):787-95. doi: 10.1016/j.euroneuro.2015.11.004. Epub 2015 Nov 14.
774 Type 2 diabetes associated variants of KCNQ1 strongly confer the risk of cardiovascular disease among the Saudi Arabian population.Genet Mol Biol. 2017 Jul-Sep;40(3):586-590. doi: 10.1590/1678-4685-GMB-2017-0005. Epub 2017 Aug 31.
775 Evaluation of four novel genetic variants affecting hemoglobin A1c levels in a population-based type 2 diabetes cohort (the HUNT2 study).BMC Med Genet. 2011 Feb 4;12:20. doi: 10.1186/1471-2350-12-20.
776 IGF2 mRNA-binding protein 2: biological function and putative role in type 2 diabetes.J Mol Endocrinol. 2009 Nov;43(5):187-95. doi: 10.1677/JME-09-0016. Epub 2009 May 8.
777 Augmentation of histone deacetylase 3 (HDAC3) epigenetic signature at the interface of proinflammation and insulin resistance in patients with type 2 diabetes.Clin Epigenetics. 2016 Nov 24;8:125. doi: 10.1186/s13148-016-0293-3. eCollection 2016.
778 Localization, cDNA sequence and genomic organization of the rat seipin gene (Bscl2) and sequence analysis in inbred rat models of Type 2 diabetes mellitus.Cytogenet Genome Res. 2002;98(1):71-4. doi: 10.1159/000068538.
779 Association of a polymorphism of BTN2A1 with type 2 diabetes mellitus in Japanese individuals.Diabet Med. 2011 Nov;28(11):1381-7. doi: 10.1111/j.1464-5491.2011.03358.x.
780 Circulating Serum Myonectin Levels in Obesity and Type 2 Diabetes Mellitus.Exp Clin Endocrinol Diabetes. 2021 Jul;129(7):528-534. doi: 10.1055/a-0896-8548. Epub 2019 Jul 24.
781 Association of circulating CTRP9 with soluble adhesion molecules and inflammatory markers in patients with type 2 diabetes mellitus and coronary artery disease.PLoS One. 2018 Jan 30;13(1):e0192159. doi: 10.1371/journal.pone.0192159. eCollection 2018.
782 HLA, complement C2, C4, properdin factor B and glyoxalase types in South Indian diabetics.Diabetes Res Clin Pract. 1985 Mar;1(1):41-7. doi: 10.1016/s0168-8227(85)80027-9.
783 The structures of the human calcium channel alpha 1 subunit (CACNL1A2) and beta subunit (CACNLB3) genes.Genomics. 1995 May 20;27(2):312-9. doi: 10.1006/geno.1995.1048.
784 Specific haplotypes of the CALPAIN-5 gene are associated with polycystic ovary syndrome.Hum Reprod. 2006 Apr;21(4):943-51. doi: 10.1093/humrep/dei443. Epub 2006 Jan 5.
785 The calpain family and human disease.Trends Mol Med. 2001 Aug;7(8):355-62. doi: 10.1016/s1471-4914(01)02049-4.
786 NLRP3 Inflammasome Polymorphism and Macrovascular Complications in Type 2 Diabetes Patients.J Diabetes Res. 2015;2015:616747. doi: 10.1155/2015/616747. Epub 2015 Jul 27.
787 Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites.Mol Genet Metab. 2007 Nov;92(3):278-82. doi: 10.1016/j.ymgme.2007.06.011. Epub 2007 Aug 2.
788 A two-step association study identifies CAV2 rs2270188 single nucleotide polymorphism interaction with fat intake in type 2 diabetes risk.J Nutr. 2011 Feb;141(2):177-81. doi: 10.3945/jn.110.124206. Epub 2010 Dec 22.
789 CD226 reduces endothelial cell glucose uptake under hyperglycemic conditions with inflammation in type 2 diabetes mellitus.Oncotarget. 2016 Mar 15;7(11):12010-23. doi: 10.18632/oncotarget.7505.
790 CD247, a novel T cell-derived diagnostic and prognostic biomarker for detecting disease progression and severity in patients with type 2 diabetes.Diabetes Care. 2015 Jan;38(1):113-8. doi: 10.2337/dc14-1544. Epub 2014 Nov 3.
791 IMPROVED HBA1C, TOTAL DAILY INSULIN DOSE, AND TREATMENT SATISFACTION WITH INSULIN PUMP THERAPY COMPARED TO MULTIPLE DAILY INSULIN INJECTIONS IN PATIENTS WITH TYPE 2 DIABETES IRRESPECTIVE OF BASELINE C-PEPTIDE LEVELS.Endocr Pract. 2018 May;24(5):446-452. doi: 10.4158/EP-2017-0234.
792 Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.Diabetologia. 2013 Feb;56(2):298-310. doi: 10.1007/s00125-012-2756-1. Epub 2012 Nov 19.
793 No association of polymorphisms in human endogenous retrovirus K18 and CD48 with schizophrenia.Psychiatr Genet. 2012 Jun;22(3):146-8. doi: 10.1097/YPG.0b013e328353953c.
794 Genetic variations of the CDC2L2 gene are associated with type 2 diabetes in a Han Chinese cohort.Diabetes Metab Res Rev. 2007 Sep;23(6):455-61. doi: 10.1002/dmrr.705.
795 Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes.Mol Cell Endocrinol. 2013 Aug 15;375(1-2):35-42. doi: 10.1016/j.mce.2013.05.003. Epub 2013 May 22.
796 Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic Cell Proliferation.Cell Metab. 2017 Apr 4;25(4):868-882.e5. doi: 10.1016/j.cmet.2017.02.004. Epub 2017 Mar 9.
797 Effects of insulin and exercise training on FGF21, its receptors and target genes in obesity and type 2 diabetes.Diabetologia. 2017 Oct;60(10):2042-2051. doi: 10.1007/s00125-017-4373-5. Epub 2017 Jul 18.
798 CILP-2 is a novel secreted protein and associated with insulin resistance.J Mol Cell Biol. 2019 Dec 19;11(12):1083-1094. doi: 10.1093/jmcb/mjz016.
799 Binding of Nitric Oxide in CDGSH-type [2Fe-2S] Clusters of the Human Mitochondrial Protein Miner2.J Biol Chem. 2017 Feb 24;292(8):3146-3153. doi: 10.1074/jbc.M116.766774. Epub 2017 Jan 12.
800 SOCS3 methylation mediated the effect of sedentary time on type 2 diabetes mellitus: The Henan Rural Cohort study.Nutr Metab Cardiovasc Dis. 2020 Apr 12;30(4):634-643. doi: 10.1016/j.numecd.2019.11.007. Epub 2019 Nov 23.
801 Involvement of the tubular ClC-type exchanger ClC-5 in glomeruli of human proteinuric nephropathies.PLoS One. 2012;7(9):e45605. doi: 10.1371/journal.pone.0045605. Epub 2012 Sep 24.
802 Rapid analysis of colipase gene variants by multicapillary electrophoresis.Electrophoresis. 2015 Jun;36(11-12):1237-43. doi: 10.1002/elps.201400551. Epub 2015 Mar 12.
803 East Asian Genome-wide association study derived loci in relation to type 2 diabetes in the Han Chinese population.Acta Biochim Pol. 2019 May 30;66(2):679-686. doi: 10.18388/abp.2020_5563.
804 Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.Nat Genet. 2015 Jul;47(7):839-46. doi: 10.1038/ng.3330. Epub 2015 Jun 8.
805 A replication study of 19 GWAS-validated type 2 diabetes at-risk variants in the Lebanese population.Diabetes Res Clin Pract. 2013 Nov;102(2):117-22. doi: 10.1016/j.diabres.2013.09.001. Epub 2013 Sep 14.
806 Common variation in oxidative phosphorylation genes is not a major cause of insulin resistance or type 2 diabetes.Diabetologia. 2012 Feb;55(2):340-8. doi: 10.1007/s00125-011-2377-0. Epub 2011 Nov 18.
807 Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle.Diabetologia. 2008 Jul;51(7):1159-68. doi: 10.1007/s00125-008-1018-8. Epub 2008 May 17.
808 The Mori and Pacific specific CREBRF variant and adult height.Int J Obes (Lond). 2020 Mar;44(3):748-752. doi: 10.1038/s41366-019-0437-6. Epub 2019 Sep 22.
809 ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis.EMBO J. 2006 Mar 8;25(5):977-86. doi: 10.1038/sj.emboj.7601008. Epub 2006 Feb 23.
810 Preliminary report: BGLIIA-BGLIIB haplotype of growth hormone cluster is associated with glucose intolerance in non-insulin-dependent diabetes mellitus and with growth hormone deficit in growth retardation.Metabolism. 2002 Jan;51(1):1-4. doi: 10.1053/meta.2002.28973.
811 Polymorphism E23K (rs5219) in the KCNJ11 gene in Euro-Brazilian subjects with type 1 and 2 diabetes.Genet Mol Res. 2017 Apr 5;16(2). doi: 10.4238/gmr16029543.
812 MicroRNA-125b-5p improves pancreatic -cell function through inhibiting JNK signaling pathway by targeting DACT1 in mice with type 2 diabetes mellitus.Life Sci. 2019 May 1;224:67-75. doi: 10.1016/j.lfs.2019.01.031. Epub 2019 Jan 23.
813 Association of acyl-CoA-binding protein (ACBP) single nucleotide polymorphisms and type 2 diabetes in two German study populations.Mol Nutr Food Res. 2007 Feb;51(2):178-84. doi: 10.1002/mnfr.200600163.
814 Relevance of -defensins (HNP1-3) and defensin -1 in diabetes.World J Gastroenterol. 2014 Jul 21;20(27):9128-37. doi: 10.3748/wjg.v20.i27.9128.
815 Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic -cell function via glycogen synthase kinase-3.FASEB J. 2016 Feb;30(2):983-93. doi: 10.1096/fj.15-279810. Epub 2015 Nov 6.
816 The economic impact of insulin-related hypoglycemia in Denmark: an analysis using the Local Impact of Hypoglycemia Tool.J Med Econ. 2017 Apr;20(4):363-370. doi: 10.1080/13696998.2016.1269774. Epub 2016 Dec 21.
817 Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary Syndrome.Sci Rep. 2016 Mar 15;6:22883. doi: 10.1038/srep22883.
818 Utility of large consanguineous family-based model for investigating the genetics of type 2 diabetes mellitus.Gene. 2014 Sep 10;548(1):22-8. doi: 10.1016/j.gene.2014.06.053. Epub 2014 Jun 30.
819 DOC2B promotes insulin sensitivity in mice via a novel KLC1-dependent mechanism in skeletal muscle.Diabetologia. 2019 May;62(5):845-859. doi: 10.1007/s00125-019-4824-2. Epub 2019 Feb 1.
820 Epigenetic associations of type 2 diabetes and BMI in an Arab population.Clin Epigenetics. 2016 Jan 28;8:13. doi: 10.1186/s13148-016-0177-6. eCollection 2016.
821 Dual specificity MAPK phosphatase 3 activates PEPCK gene transcription and increases gluconeogenesis in rat hepatoma cells.J Biol Chem. 2005 Oct 28;280(43):36013-8. doi: 10.1074/jbc.M508027200. Epub 2005 Aug 26.
822 Association analysis of the ephrin-B2 gene in African-Americans with end-stage renal disease.Am J Nephrol. 2008;28(6):914-20. doi: 10.1159/000141934. Epub 2008 Jun 26.
823 The effects of metformin on body mass index and glucose tolerance in obese adolescents with fasting hyperinsulinemia and a family history of type 2 diabetes.Pediatrics. 2001 Apr;107(4):E55. doi: 10.1542/peds.107.4.e55.
824 EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families.Diabetes. 2006 Apr;55(4):1171-6. doi: 10.2337/diabetes.55.04.06.db05-1298.
825 Identification and characterization of differentially expressed genes in Type 2 Diabetes using in silico approach.Comput Biol Chem. 2019 Apr;79:24-35. doi: 10.1016/j.compbiolchem.2019.01.010. Epub 2019 Jan 24.
826 When Place Matters: Shuttling of Enolase-1 Across Cellular Compartments.Front Cell Dev Biol. 2019 Apr 26;7:61. doi: 10.3389/fcell.2019.00061. eCollection 2019.
827 Increased Expression of Ecto-NOX Disulfide-thiol Exchanger 1 (ENOX1) in Diabetic Mice Retina and its Involvement in Diabetic Retinopathy Development.In Vivo. 2019 Nov-Dec;33(6):1801-1806. doi: 10.21873/invivo.11671.
828 Endoplasmic reticulum oxidoreductin-1 (Ero1) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress.J Biol Chem. 2013 Oct 25;288(43):31010-8. doi: 10.1074/jbc.M113.510065. Epub 2013 Sep 10.
829 Polymorphisms near EXOC4 and LRGUK on chromosome 7q32 are associated with Type 2 Diabetes and fasting glucose; the NHLBI Family Heart Study.BMC Med Genet. 2008 May 22;9:46. doi: 10.1186/1471-2350-9-46.
830 Genetic association of single nucleotide polymorphisms in endonuclease G-like 1 gene with type 2 diabetes in a Japanese population.Diabetologia. 2007 Jun;50(6):1218-27. doi: 10.1007/s00125-007-0631-2. Epub 2007 Apr 6.
831 Genetic variants in desaturase gene, erythrocyte fatty acids, and risk for type 2 diabetes in Chinese Hans.Nutrition. 2014 Jul-Aug;30(7-8):897-902. doi: 10.1016/j.nut.2014.01.006. Epub 2014 Jan 30.
832 Joint ancestry and association testing in admixed individuals.PLoS Comput Biol. 2011 Dec;7(12):e1002325. doi: 10.1371/journal.pcbi.1002325. Epub 2011 Dec 22.
833 Asprosin attenuates insulin signaling pathway through PKC-activated ER stress and inflammation in skeletal muscle.J Cell Physiol. 2019 Nov;234(11):20888-20899. doi: 10.1002/jcp.28694. Epub 2019 Apr 17.
834 An SCF(FBXO28) E3 Ligase Protects Pancreatic -Cells from Apoptosis.Int J Mol Sci. 2018 Mar 24;19(4):975. doi: 10.3390/ijms19040975.
835 Occurrence over time and regression of nonalcoholic fatty liver disease in type 2 diabetes.Diabetes Metab Res Rev. 2017 May;33(4). doi: 10.1002/dmrr.2878. Epub 2017 Jan 27.
836 Gaussian graphical models identified food intake networks and risk of type 2 diabetes, CVD, and cancer in the EPIC-Potsdam study.Eur J Nutr. 2019 Jun;58(4):1673-1686. doi: 10.1007/s00394-018-1714-1. Epub 2018 May 14.
837 Functional proteasome complex is required for turnover of islet amyloid polypeptide in pancreatic -cells.J Biol Chem. 2018 Sep 14;293(37):14210-14223. doi: 10.1074/jbc.RA118.002414. Epub 2018 Jul 16.
838 Regulation of testicular steroidogenesis by Foxa3 via transcriptional modulation of ER signaling in type 2 diabetes mellitus (T2DM).Biochem Biophys Res Commun. 2017 Aug 26;490(3):786-793. doi: 10.1016/j.bbrc.2017.06.118. Epub 2017 Jun 21.
839 The Uyghur population and genetic susceptibility to type 2 diabetes: potential role for variants in CAPN10, APM1 and FUT6 genes.J Cell Mol Med. 2016 Nov;20(11):2138-2147. doi: 10.1111/jcmm.12911. Epub 2016 Jul 4.
840 Reduced mRNA and protein expression of perilipin A and G0/G1 switch gene 2 (G0S2) in human adipose tissue in poorly controlled type 2 diabetes.J Clin Endocrinol Metab. 2012 Jul;97(7):E1348-52. doi: 10.1210/jc.2012-1159. Epub 2012 Apr 24.
841 GALNT2 expression is reduced in patients with Type 2 diabetes: possible role of hyperglycemia.PLoS One. 2013 Jul 22;8(7):e70159. doi: 10.1371/journal.pone.0070159. Print 2013.
842 Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes.Cell Death Differ. 2012 Jun;19(6):1003-12. doi: 10.1038/cdd.2011.183. Epub 2012 Jan 6.
843 A study of human growth hormone and insulin gene regions in relation to metabolic control of non-insulin-dependent diabetes mellitus.Metabolism. 2000 Apr;49(4):424-6. doi: 10.1016/s0026-0495(00)81092-6.
844 Transcriptomic and network component analysis of glycerol kinase in skeletal muscle using a mouse model of glycerol kinase deficiency.Mol Genet Metab. 2009 Mar;96(3):106-12. doi: 10.1016/j.ymgme.2008.11.163. Epub 2009 Jan 3.
845 Identification of a genetic locus on chromosome 4q34-35 for type 2 diabetes with overweight.Exp Mol Med. 2013 Feb 8;45(2):e7. doi: 10.1038/emm.2013.5.
846 Regulating the effects of GPR21, a novel target for type 2 diabetes.Sci Rep. 2016 May 31;6:27002. doi: 10.1038/srep27002.
847 An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins.Nat Commun. 2014 Dec 12;5:5719. doi: 10.1038/ncomms6719.
848 Selenium Levels in Community Dwellers with Type 2 Diabetes Mellitus.Biol Trace Elem Res. 2019 Oct;191(2):354-362. doi: 10.1007/s12011-019-1645-6. Epub 2019 Feb 6.
849 Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans.Hum Genomics. 2019 May 15;13(1):21. doi: 10.1186/s40246-019-0205-7.
850 Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients.Diabetes. 1999 Feb;48(2):403-7. doi: 10.2337/diabetes.48.2.403.
851 Further evidence for the association of MMP9 with nephropathy in type 2 diabetes and application of DNA pooling technology to candidate gene screening.J Nephrol. 2008 May-Jun;21(3):400-5.
852 Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion.Diabetologia. 2014 Jan;57(1):122-8. doi: 10.1007/s00125-013-3089-4. Epub 2013 Oct 23.
853 Impaired postprandial blood flow in adipose tissue may be an early marker of insulin resistance in type 2 diabetes.Diabetes Care. 2007 Dec;30(12):3128-30. doi: 10.2337/dc07-0699. Epub 2007 Sep 21.
854 The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity.Cell Death Dis. 2018 Feb 15;9(3):279. doi: 10.1038/s41419-018-0272-z.
855 The Impact of Small RNA Interference Against Homer1 on Rats with Type 2 Diabetes and ERK Phosphorylation.Cell Biochem Biophys. 2015 Dec;73(3):597-601. doi: 10.1007/s12013-015-0657-x.
856 Impact of diabetes mellitus on the relationships between iron-, inflammatory- and oxidative stress status.Diabetes Metab Res Rev. 2006 Nov-Dec;22(6):444-54. doi: 10.1002/dmrr.635.
857 Impact of diabetes-related gene polymorphisms on the clinical characteristics of type 2 diabetes Chinese Han population.Oncotarget. 2016 Dec 20;7(51):85464-85471. doi: 10.18632/oncotarget.13399.
858 Association of humoral immunity to human Hsp60 with the IL-6 gene polymorphism C-174G in patients with type 2 diabetes and controls.Horm Metab Res. 2005 Apr;37(4):257-63. doi: 10.1055/s-2005-861209.
859 IGF2BP1, IGF2BP2 and IGF2BP3 genotype, haplotype and genetic model studies in metabolic syndrome traits and diabetes.Growth Horm IGF Res. 2010 Aug;20(4):310-8. doi: 10.1016/j.ghir.2010.04.002.
860 Type II diabetes mellitus and the incidence of amyotrophic lateral sclerosis.J Neurol. 2019 Sep;266(9):2233-2243. doi: 10.1007/s00415-019-09405-x. Epub 2019 May 31.
861 Development of the influence, motivation, and patient activation in diabetes (IMPACT-D? measure.Diabetes Res Clin Pract. 2020 Jan;159:107965. doi: 10.1016/j.diabres.2019.107965. Epub 2019 Dec 2.
862 The IHPK1 gene is disrupted at the 3p21.31 breakpoint of t(3;9) in a family with type 2 diabetes mellitus.J Hum Genet. 2004;49(7):360-365. doi: 10.1007/s10038-004-0158-z. Epub 2004 Jun 18.
863 Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3.Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):775-80. doi: 10.1073/pnas.0911591107. Epub 2009 Dec 22.
864 Different inverse association of large high-density lipoprotein subclasses with exacerbation of insulin resistance and incidence of type 2 diabetes: The Nagahama study.Diabetes Res Clin Pract. 2017 May;127:123-131. doi: 10.1016/j.diabres.2017.03.018. Epub 2017 Mar 21.
865 Association of KALRN, ADIPOQ, and FTO gene polymorphism in type 2 diabetic patients with coronary artery disease: possible predisposing markers.Coron Artery Dis. 2016 Sep;27(6):490-6. doi: 10.1097/MCA.0000000000000386.
866 Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese.J Clin Endocrinol Metab. 2010 May;95(5):2418-25. doi: 10.1210/jc.2009-2077. Epub 2010 Mar 9.
867 Three novel alleles in the Kell blood group system resulting in the Knull phenotype and the first in a Native American.Transfusion. 2013 Nov;53(11 Suppl 2):2867-71. doi: 10.1111/trf.12205. Epub 2013 Apr 15.
868 Development of ARMS-PCR assay for genotyping of Pro12Ala SNP of PPARG gene: a cost effective way for case-control studies of type 2 diabetes in developing countries.Mol Biol Rep. 2014 Sep;41(9):5585-91. doi: 10.1007/s11033-014-3213-7. Epub 2014 Jul 26.
869 Association of APOE (Hha1) and ACE (I/D) gene polymorphisms with type 2 diabetes mellitus in North West India.Diabetes Res Clin Pract. 2006 Oct;74(1):95-102. doi: 10.1016/j.diabres.2006.03.013. Epub 2006 Apr 18.
870 Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene.Diabetes. 2005 Jun;54(6):1892-5. doi: 10.2337/diabetes.54.6.1892.
871 Lipoic acid synthase (LASY): a novel role in inflammation, mitochondrial function, and insulin resistance.Diabetes. 2009 Mar;58(3):600-8. doi: 10.2337/db08-0473. Epub 2008 Dec 15.
872 LPIN2 is associated with type 2 diabetes, glucose metabolism, and body composition.Diabetes. 2007 Dec;56(12):3020-6. doi: 10.2337/db07-0338. Epub 2007 Sep 5.
873 Variants associated with type 2 diabetes identified by the transethnic meta-analysis study: assessment in American Indians and evidence for a new signal in LPP.Diabetologia. 2014 Nov;57(11):2334-8. doi: 10.1007/s00125-014-3351-4. Epub 2014 Aug 12.
874 Inactivation of specific cell transcription factors in type 2 diabetes.J Clin Invest. 2013 Aug;123(8):3305-16. doi: 10.1172/JCI65390. Epub 2013 Jul 1.
875 Comparison of Transcriptome Between Type 2 Diabetes Mellitus and Impaired Fasting Glucose.Med Sci Monit. 2016 Dec 1;22:4699-4706. doi: 10.12659/msm.896772.
876 The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.Diabetologia. 2007 Dec;50(12):2486-94. doi: 10.1007/s00125-007-0816-8. Epub 2007 Sep 30.
877 Risk of cardiovascular events associated with dipeptidyl peptidase-4 inhibitors in patients with diabetes with and without chronic kidney disease: A nationwide cohort study.PLoS One. 2019 May 21;14(5):e0215248. doi: 10.1371/journal.pone.0215248. eCollection 2019.
878 MicroRNA genetic variations: association with type 2 diabetes.Acta Diabetol. 2013 Dec;50(6):867-72. doi: 10.1007/s00592-013-0469-7. Epub 2013 Mar 27.
879 Embryonic stem cell-derived pancreatic endoderm transplant with MCT1-suppressing miR-495 attenuates type II diabetes in mice.Endocr J. 2015;62(10):907-20. doi: 10.1507/endocrj.EJ15-0186. Epub 2015 Jul 25.
880 Association between peroxisome proliferator-activated receptor-gamma coactivator-1alpha gene polymorphisms and type 2 diabetes in southern Chinese population: role of altered interaction with myocyte enhancer factor 2C.Chin Med J (Engl). 2007 Nov 5;120(21):1878-85.
881 Serum Levels of Meteorin-Like (Metrnl) Are Increased in Patients with Newly Diagnosed Type 2 Diabetes Mellitus and Are Associated with Insulin Resistance.Med Sci Monit. 2019 Mar 31;25:2337-2343. doi: 10.12659/MSM.915331.
882 The transcription of MGAT4A glycosyl transferase is increased in white cells of peripheral blood of type 2 diabetes patients.BMC Genet. 2007 Oct 22;8:73. doi: 10.1186/1471-2156-8-73.
883 Inactive Matrix Gla-Protein and Arterial Stiffness in Type 2 Diabetes Mellitus.Am J Hypertens. 2017 Feb;30(2):196-201. doi: 10.1093/ajh/hpw146. Epub 2016 Dec 7.
884 Evaluation of the microsomal glutathione S-transferase 3 (MGST3) locus on 1q23 as a Type 2 diabetes susceptibility gene in Pima Indians.Hum Genet. 2003 Sep;113(4):353-8. doi: 10.1007/s00439-003-0980-y. Epub 2003 Jul 26.
885 Estrogen receptor alpha gene polymorphisms are associated with type 2 diabetes and fasting glucose in male subjects.Mol Cell Biochem. 2012 Jan;359(1-2):225-33. doi: 10.1007/s11010-011-1017-9. Epub 2011 Aug 12.
886 The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation.Mol Metab. 2019 May;23:14-23. doi: 10.1016/j.molmet.2019.02.003. Epub 2019 Feb 20.
887 Analysis of novel risk loci for type 2 diabetes in a general French population: the D.E.S.I.R. study.J Mol Med (Berl). 2008 Mar;86(3):341-8. doi: 10.1007/s00109-007-0295-x. Epub 2008 Jan 22.
888 Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians.Diabetes. 2013 Aug;62(8):2984-91. doi: 10.2337/db12-1767. Epub 2013 Apr 29.
889 Regulation of alternative splicing in human obesity loci.Obesity (Silver Spring). 2016 Oct;24(10):2033-7. doi: 10.1002/oby.21587. Epub 2016 Aug 12.
890 Arterial calcification: a tumor necrosis factor-alpha mediated vascular Wnt-opathy.Transl Res. 2008 May;151(5):233-9. doi: 10.1016/j.trsl.2007.12.005. Epub 2008 Jan 22.
891 Over-expression of miR375 reduces glucose-induced insulin secretion in Nit-1 cells.Mol Biol Rep. 2011 Jun;38(5):3061-5. doi: 10.1007/s11033-010-9973-9. Epub 2010 Feb 3.
892 MYH9 gene polymorphisms may be associated with cerebrovascular blood flow in patients with type 2 diabetes.Genet Mol Res. 2015 Feb 6;14(1):1008-16. doi: 10.4238/2015.February.6.4.
893 New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.J Hum Genet. 2013 Jun;58(6):362-5. doi: 10.1038/jhg.2013.14. Epub 2013 Apr 11.
894 Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis.Clin Endocrinol (Oxf). 2014 Nov;81(5):702-10. doi: 10.1111/cen.12428. Epub 2014 Mar 13.
895 Prevalence of the DNA repair enzyme-NEIL1 gene mutation in patients with type 2 diabetes in the Turkish population.J Endocrinol Invest. 2012 Apr;35(4):401-6. doi: 10.3275/8017. Epub 2011 Oct 6.
896 Coordinated augmentation of NFAT and NOD signaling mediates proliferative VSMC phenotype switch under hyperinsulinemia.Atherosclerosis. 2016 Mar;246:257-66. doi: 10.1016/j.atherosclerosis.2016.01.006. Epub 2016 Jan 13.
897 Specific inflammasomes in complex diseases.Clin Immunol. 2013 Jun;147(3):223-8. doi: 10.1016/j.clim.2012.12.006. Epub 2012 Dec 21.
898 Application of a novel score test for genetic association incorporating gene-gene interaction suggests functionality for prostate cancer susceptibility regions.Hum Hered. 2011;72(3):182-93. doi: 10.1159/000331222. Epub 2011 Nov 11.
899 The relationship between NR2E1 and subclinical inflammation in newly diagnosed type 2 diabetic patients.J Diabetes Complications. 2015 May-Jun;29(4):589-94. doi: 10.1016/j.jdiacomp.2014.12.018. Epub 2014 Dec 31.
900 Elevated levels of renal and circulating Nop-7-associated 2 (NSA2) in rat and mouse models of diabetes, in mesangial cells in vitro and in patients with diabetic nephropathy.Diabetologia. 2012 Mar;55(3):825-34. doi: 10.1007/s00125-011-2373-4. Epub 2011 Nov 18.
901 NSD2 is downregulated in T2DM and promotes cell proliferation and insulin secretion through the transcriptionally regulation of PDX1.Mol Med Rep. 2018 Sep;18(3):3513-3520. doi: 10.3892/mmr.2018.9338. Epub 2018 Jul 31.
902 A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell.Am J Hum Genet. 2014 Feb 6;94(2):186-97. doi: 10.1016/j.ajhg.2013.12.011. Epub 2014 Jan 16.
903 Defective metabolism of oxidized phospholipid by HDL from people with type 2 diabetes.Diabetes. 2006 Nov;55(11):3099-103. doi: 10.2337/db06-0723.
904 PCLO variants are nominally associated with early-onset type 2 diabetes and insulin resistance in Pima Indians.Diabetes. 2008 Nov;57(11):3156-60. doi: 10.2337/db07-1800. Epub 2008 Jul 22.
905 Adolescent type 2 diabetes: Comparing the Pediatric Diabetes Consortium and Germany/Austria/Luxemburg Pediatric Diabetes Prospective registries.Pediatr Diabetes. 2018 Nov;19(7):1156-1163. doi: 10.1111/pedi.12712. Epub 2018 Jul 17.
906 The rs7204609 polymorphism in the fat mass and obesity-associated gene is positively associated with central obesity and microalbuminuria in patients with type 2 diabetes from Southern Brazil.J Ren Nutr. 2012 Mar;22(2):228-236. doi: 10.1053/j.jrn.2011.03.004. Epub 2011 Jul 13.
907 Autoantibodies against PFDN2 are associated with an increased risk of type 2 diabetes: A case-control study.Diabetes Metab Res Rev. 2017 Nov;33(8):10.1002/dmrr.2922. doi: 10.1002/dmrr.2922. Epub 2017 Aug 30.
908 Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells.J Biol Chem. 2011 Feb 11;286(6):4216-25. doi: 10.1074/jbc.M110.200295. Epub 2010 Dec 2.
909 PIWI-interacting RNAs as novel regulators of pancreatic beta cell function.Diabetologia. 2017 Oct;60(10):1977-1986. doi: 10.1007/s00125-017-4368-2. Epub 2017 Jul 16.
910 Increased abundance of the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1) in patients with obesity and type 2 diabetes: evidence for altered adiponectin signalling.Diabetologia. 2011 Aug;54(8):2122-31. doi: 10.1007/s00125-011-2173-x. Epub 2011 May 12.
911 The role of clinical response to metformin in patients newly diagnosed with type 2 diabetes: a monotherapy study.Clin Exp Med. 2015 May;15(2):159-65. doi: 10.1007/s10238-014-0283-8. Epub 2014 Apr 17.
912 Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients.Eur J Endocrinol. 2016 Dec;175(6):531-540. doi: 10.1530/EJE-16-0347. Epub 2016 Sep 8.
913 Genetic analysis of human type 1 protein phosphatase inhibitor 2 in insulin-resistant Pima Indians.Genomics. 1997 Apr 1;41(1):110-4. doi: 10.1006/geno.1997.4649.
914 PRDX1 is involved in palmitate induced insulin resistance via regulating the activity of p38MAPK in HepG2 cells.Biochem Biophys Res Commun. 2015 Oct 2;465(4):670-7. doi: 10.1016/j.bbrc.2015.08.008. Epub 2015 Aug 21.
915 Flavonoids extracted from mulberry (Morus alba L.) leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes.J Ethnopharmacol. 2020 Feb 10;248:112326. doi: 10.1016/j.jep.2019.112326. Epub 2019 Oct 19.
916 EPCR Ser219Gly: elevated sEPCR, prothrombin F1+2, risk for coronary heart disease, and increased sEPCR shedding in vitro.Atherosclerosis. 2005 Dec;183(2):283-92. doi: 10.1016/j.atherosclerosis.2005.02.028.
917 The Type 2 Diabetes Susceptibility PROX1 Gene Variants Are Associated with Postprandial Plasma Metabolites Profile in Non-Diabetic Men.Nutrients. 2019 Apr 19;11(4):882. doi: 10.3390/nu11040882.
918 Genome-Wide Assessment for RestingHeart Rate and Shared Genetics WithCardiometabolic Traits and Type 2 Diabetes.J Am Coll Cardiol. 2019 Oct 29;74(17):2162-2174. doi: 10.1016/j.jacc.2019.08.1055.
919 Obesity-related genomic loci are associated with type 2 diabetes in a Han Chinese population.PLoS One. 2014 Aug 5;9(8):e104486. doi: 10.1371/journal.pone.0104486. eCollection 2014.
920 Validation of the association between PSMA6 -8 C/G polymorphism and type 2 diabetes mellitus in Chinese Dongxiang and Han populations.Diabetes Res Clin Pract. 2012 Nov;98(2):295-301. doi: 10.1016/j.diabres.2012.09.021. Epub 2012 Sep 29.
921 Interaction between Erythrocyte Phospholipid Fatty Acids Composition and Variants of Inflammation-Related Genes on Type 2 Diabetes.J Nutrigenet Nutrigenomics. 2014;7(4-6):252-63. doi: 10.1159/000381347. Epub 2015 May 7.
922 Prothymosin- Overexpression Contributes to the Development of Insulin Resistance.J Clin Endocrinol Metab. 2015 Nov;100(11):4114-23. doi: 10.1210/jc.2015-2277. Epub 2015 Sep 8.
923 Positive Association Between Type 2 Diabetes Risk Alleles Near CDKAL1 and Reduced Birthweight in Chinese Han Individuals.Chin Med J (Engl). 2015 Jul 20;128(14):1873-8. doi: 10.4103/0366-6999.160489.
924 Sib-pair analysis of adenosine deaminase locus in NIDDM.Diabetes. 1992 Dec;41(12):1640-3. doi: 10.2337/diab.41.12.1640.
925 Association between polymorphisms in RAPGEF1, TP53, NRF1 and type 2 diabetes in Chinese Han population.Diabetes Res Clin Pract. 2011 Feb;91(2):171-6. doi: 10.1016/j.diabres.2010.11.019. Epub 2010 Dec 13.
926 Genetics of non-insulin-dependent (type-II) diabetes mellitus.Annu Rev Med. 1996;47:509-31. doi: 10.1146/annurev.med.47.1.509.
927 Eugenosedin-A improves glucose metabolism and inhibits MAPKs expression in streptozotocin/nicotinamide-induced diabetic rats.Kaohsiung J Med Sci. 2018 Mar;34(3):142-149. doi: 10.1016/j.kjms.2017.11.003. Epub 2017 Nov 29.
928 Association of rs734312 and rs10010131 polymorphisms in WFS1 gene with type 2 diabetes mellitus: a meta-analysis.Endocr J. 2013;60(4):441-7. Epub 2012 Dec 15.
929 Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes.Sci Rep. 2017 Jul 20;7(1):6037. doi: 10.1038/s41598-017-06158-3.
930 Inhibition of Miro1 disturbs mitophagy and pancreatic -cell function interfering insulin release via IRS-Akt-Foxo1 in diabetes.Oncotarget. 2017 Sep 16;8(53):90693-90705. doi: 10.18632/oncotarget.20963. eCollection 2017 Oct 31.
931 Role and regulation of acylethanolamides in energy balance: focus on adipocytes and beta-cells.Br J Pharmacol. 2007 Nov;152(5):676-90. doi: 10.1038/sj.bjp.0707424. Epub 2007 Aug 20.
932 Analysis of SLC16A11 Variants in 12,811 American Indians: Genotype-Obesity Interaction for Type 2 Diabetes and an Association With RNASEK Expression.Diabetes. 2016 Feb;65(2):510-9. doi: 10.2337/db15-0571. Epub 2015 Oct 20.
933 Redundant roles of the phosphatidate phosphatase family in triacylglycerol synthesis in human adipocytes.Diabetologia. 2016 Sep;59(9):1985-94. doi: 10.1007/s00125-016-4018-0. Epub 2016 Jun 25.
934 Twelve weeks of low volume sprint interval training improves cardio-metabolic health outcomes in overweight females.J Sports Sci. 2019 Jun;37(11):1257-1264. doi: 10.1080/02640414.2018.1554615. Epub 2018 Dec 18.
935 Calcium release channel RyR2 regulates insulin release and glucose homeostasis.J Clin Invest. 2015 May;125(5):1968-78. doi: 10.1172/JCI79273. Epub 2015 Apr 6.
936 Segregation analysis of non-insulin-dependent diabetes mellitus in Pima Indians: evidence for a major-gene effect.Am J Hum Genet. 1995 Jul;57(1):160-70.
937 Novel epigenetic determinants of type 2 diabetes in Mexican-American families.Hum Mol Genet. 2015 Sep 15;24(18):5330-44. doi: 10.1093/hmg/ddv232. Epub 2015 Jun 22.
938 Synthesis of cytochrome c oxidase 1 (SCO1) inhibits insulin sensitivity by decreasing copper levels in adipocytes.Biochem Biophys Res Commun. 2017 Sep 23;491(3):814-820. doi: 10.1016/j.bbrc.2017.06.124. Epub 2017 Jun 21.
939 Calpain inhibition stabilizes the platelet proteome and reactivity in diabetes.Blood. 2012 Jul 12;120(2):415-23. doi: 10.1182/blood-2011-12-399980. Epub 2012 Jun 4.
940 Preliminary structural characterization and hypoglycemic effects of an acidic polysaccharide SERP1 from the residue of Sarcandra glabra.Carbohydr Polym. 2017 Nov 15;176:140-151. doi: 10.1016/j.carbpol.2017.08.071. Epub 2017 Aug 19.
941 Sestrin 3 regulation in type 2 diabetic patients and its influence on metabolism and differentiation in skeletal muscle.Am J Physiol Endocrinol Metab. 2013 Dec 1;305(11):E1408-14. doi: 10.1152/ajpendo.00212.2013. Epub 2013 Oct 15.
942 Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes.J Biol Chem. 2011 Aug 12;286(32):28544-55. doi: 10.1074/jbc.M111.255646. Epub 2011 Jun 13.
943 Siglec-5 is a novel marker of critical limb ischemia in patients with diabetes.Sci Rep. 2017 Sep 12;7(1):11272. doi: 10.1038/s41598-017-11820-x.
944 Smad5 regulates Akt2 expression and insulin-induced glucose uptake in L6 myotubes.Mol Cell Endocrinol. 2010 May 5;319(1-2):30-8. doi: 10.1016/j.mce.2010.01.003. Epub 2010 Jan 14.
945 Omega-3 fatty acid docosahexaenoic acid increases SorLA/LR11, a sorting protein with reduced expression in sporadic Alzheimer's disease (AD): relevance to AD prevention.J Neurosci. 2007 Dec 26;27(52):14299-307. doi: 10.1523/JNEUROSCI.3593-07.2007.
946 SOX6 gene polymorphism (rs16933090) and markers of subclinical atherosclerosis in patients with type 2 diabetes mellitus.Int Angiol. 2016 Dec;35(6):552-556. Epub 2016 Feb 11.
947 Mindin: a novel marker for podocyte injury in diabetic nephropathy.Nephrol Dial Transplant. 2011 Jul;26(7):2153-60. doi: 10.1093/ndt/gfq708. Epub 2010 Nov 22.
948 Effect of obesity and type 2 diabetes, and glucose ingestion on circulating spexin concentration in adolescents.Pediatr Diabetes. 2018 Mar;19(2):212-216. doi: 10.1111/pedi.12549. Epub 2017 Jun 19.
949 Mitochondrial uncoupling has no effect on microvascular complications in type 2 diabetes.Sci Rep. 2019 Jan 29;9(1):881. doi: 10.1038/s41598-018-37376-y.
950 STEAP4 expression in human islets is associated with differences in body mass index, sex, HbA1c, and inflammation.Endocrine. 2017 Jun;56(3):528-537. doi: 10.1007/s12020-017-1297-2. Epub 2017 Apr 12.
951 Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease.PLoS One. 2013 Dec 12;8(12):e83122. doi: 10.1371/journal.pone.0083122. eCollection 2013.
952 New Roles of Syntaxin-1A in Insulin Granule Exocytosis and Replenishment.J Biol Chem. 2017 Feb 10;292(6):2203-2216. doi: 10.1074/jbc.M116.769885. Epub 2016 Dec 28.
953 The assembly of lipid droplets and its relation to cellular insulin sensitivity.Biochem Soc Trans. 2009 Oct;37(Pt 5):981-5. doi: 10.1042/BST0370981.
954 The SNARE protein SNAP23 and the SNARE-interacting protein Munc18c in human skeletal muscle are implicated in insulin resistance/type 2 diabetes.Diabetes. 2010 Aug;59(8):1870-8. doi: 10.2337/db09-1503. Epub 2010 May 11.
955 Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion.PLoS Genet. 2011 Oct;7(10):e1002323. doi: 10.1371/journal.pgen.1002323. Epub 2011 Oct 6.
956 Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.Mol Cell Endocrinol. 2012 Nov 25;364(1-2):36-45. doi: 10.1016/j.mce.2012.08.009. Epub 2012 Aug 23.
957 Type 2 diabetes and the genetics of signal transduction: a study of interaction between adenosine deaminase and acid phosphatase locus 1 polymorphisms.Metabolism. 2004 Aug;53(8):995-1001. doi: 10.1016/j.metabol.2004.03.006.
958 Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes.Gut. 2009 Mar;58(3):337-46. doi: 10.1136/gut.2008.148932. Epub 2008 Nov 27.
959 Association of TRB3 gene Q84R polymorphism with type 2 diabetes mellitus in Chinese population.Endocrine. 2009 Jun;35(3):414-9. doi: 10.1007/s12020-009-9162-6. Epub 2009 Mar 17.
960 Genetic variants at CDC123/CAMK1D and SPRY2 are associated with susceptibility to type 2 diabetes in the Japanese population.Diabetologia. 2011 Dec;54(12):3071-7. doi: 10.1007/s00125-011-2293-3. Epub 2011 Sep 10.
961 Blood-based analysis of type-2 diabetes mellitus susceptibility genes identifies specific transcript variants with deregulated expression and association with disease risk.Sci Rep. 2019 Feb 6;9(1):1512. doi: 10.1038/s41598-018-37856-1.
962 Gender differences in the association of gene polymorphisms with type 2 diabetes mellitus.Int J Mol Med. 2007 Apr;19(4):631-7.
963 Allelic expression imbalance screening of genes in chromosome 1q21-24 region to identify functional variants for Type 2 diabetes susceptibility.Physiol Genomics. 2013 Jul 2;45(13):509-20. doi: 10.1152/physiolgenomics.00048.2013. Epub 2013 May 14.
964 Thrap3 docks on phosphoserine 273 of PPAR and controls diabetic gene programming.Genes Dev. 2014 Nov 1;28(21):2361-9. doi: 10.1101/gad.249367.114. Epub 2014 Oct 14.
965 Evaluation of tight junction protein 1 encoding zona occludens 1 as a candidate gene for albuminuria in a Mexican American population.Exp Clin Endocrinol Diabetes. 2006 Sep;114(8):432-7. doi: 10.1055/s-2006-924328.
966 HNF1 defect influences post-prandial lipid regulation.PLoS One. 2017 May 11;12(5):e0177110. doi: 10.1371/journal.pone.0177110. eCollection 2017.
967 Transducin-like enhancer of split 3 (TLE3) in adipose tissue is increased in situations characterized by decreased PPAR gene expression.J Mol Med (Berl). 2015 Jan;93(1):83-92. doi: 10.1007/s00109-014-1207-5. Epub 2014 Sep 25.
968 Peroxisome proliferator-activated receptor pathway gene polymorphism associated with extent of coronary artery disease in patients with type 2 diabetes in the bypass angioplasty revascularization investigation 2 diabetes trial.Circulation. 2011 Sep 27;124(13):1426-34. doi: 10.1161/CIRCULATIONAHA.111.029173. Epub 2011 Sep 12.
969 Upregulation of Tumor Necrosis Factor--Induced Protein 8-Like 2 mRNA Is Negatively Correlated with Serum Concentrations of Tumor Necrosis Factor- and Interleukin 6 in Type 2 Diabetes Mellitus.J Diabetes Res. 2017;2017:4802319. doi: 10.1155/2017/4802319. Epub 2017 May 24.
970 Linking Alzheimer's disease and type 2 diabetes: Novel shared susceptibility genes detected by cFDR approach.J Neurol Sci. 2017 Sep 15;380:262-272. doi: 10.1016/j.jns.2017.07.044. Epub 2017 Aug 1.
971 Identifying candidate genes for Type 2 Diabetes Mellitus and obesity through gene expression profiling in multiple tissues or cells.J Diabetes Res. 2013;2013:970435. doi: 10.1155/2013/970435. Epub 2013 Dec 26.
972 TOX and CDKN2A/B Gene Polymorphisms Are Associated with Type 2 Diabetes in Han Chinese.Sci Rep. 2015 Jul 3;5:11900. doi: 10.1038/srep11900.
973 The effects of TLR3, TRIF and TRAF3 SNPs and interactions with environmental factors on type 2 diabetes mellitus and vascular complications in a Han Chinese population.Gene. 2017 Aug 30;626:41-47. doi: 10.1016/j.gene.2017.05.011. Epub 2017 May 4.
974 Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes.Hum Genet. 2013 Jun;132(6):697-707. doi: 10.1007/s00439-013-1278-3. Epub 2013 Mar 7.
975 Tshz1 Regulates Pancreatic -Cell Maturation.Diabetes. 2015 Aug;64(8):2905-14. doi: 10.2337/db14-1443. Epub 2015 Apr 27.
976 Benefit and harm of intensive blood pressure treatment: Derivation and validation of risk models using data from the SPRINT and ACCORD trials.PLoS Med. 2017 Oct 17;14(10):e1002410. doi: 10.1371/journal.pmed.1002410. eCollection 2017 Oct.
977 Neutral Ceramidase Secreted Via Exosome Protects Against Palmitate-Induced Apoptosis in INS-1 Cells.Exp Clin Endocrinol Diabetes. 2017 Feb;125(2):130-135. doi: 10.1055/s-0042-116314. Epub 2016 Dec 22.
978 Mitochondrial DNA Mutations Associated with Type 2 Diabetes Mellitus in Chinese Uyghur Population.Sci Rep. 2017 Dec 5;7(1):16989. doi: 10.1038/s41598-017-17086-7.
979 Associations of Salivary BPIFA1 Protein in Chronic Periodontitis Patients with Type 2 Diabetes Mellitus.Int J Endocrinol. 2017;2017:1087017. doi: 10.1155/2017/1087017. Epub 2017 Oct 4.
980 Association of osteoglycin and FAM5C with bone turnover markers, bone mineral density, and vertebral fractures in postmenopausal women with type 2 diabetes mellitus.Bone. 2017 Feb;95:5-10. doi: 10.1016/j.bone.2016.11.007. Epub 2016 Nov 8.
981 Identification of Novel Circulating Biomarkers Predicting Rapid Decline in Renal Function in Type 2 Diabetes: The Fremantle Diabetes Study Phase II.Diabetes Care. 2017 Nov;40(11):1548-1555. doi: 10.2337/dc17-0911. Epub 2017 Aug 29.
982 The association between sleep duration, snoring and prevalent type 2 diabetes mellitus with regard to gender and menopausal status: the CKB study in Zhejiang rural area, China.Acta Diabetol. 2017 Jan;54(1):81-90. doi: 10.1007/s00592-016-0918-1. Epub 2016 Sep 24.
983 Visceral adipose tissue macrophage-targeted TACE silencing to treat obesity-induced type 2 diabetes.Biomaterials. 2017 Dec;148:81-89. doi: 10.1016/j.biomaterials.2017.09.023. Epub 2017 Sep 23.
984 Computational analyses of type 2 diabetes-associated loci identified by genome-wide association studies.J Diabetes. 2017 Apr;9(4):362-377. doi: 10.1111/1753-0407.12421. Epub 2016 Jul 27.
985 Histological evidence that metformin reverses the adverse effects of diabetes on orthodontic tooth movement in rats.J Mol Histol. 2017 Apr;48(2):73-81. doi: 10.1007/s10735-016-9707-y. Epub 2016 Dec 15.
986 Analysis of Serum Endothelial Cell-Specific Molecule 1 (Endocan) Level in Type 2 Diabetes Mellitus With Acute ST-Segment Elevation Myocardial Infarction and its Correlation: A Pilot Study.Angiology. 2017 Jan;68(1):74-78. doi: 10.1177/0003319716634581. Epub 2016 Feb 28.
987 Hepatic Activation of the FAM3C-HSF1-CaM Pathway Attenuates Hyperglycemia of Obese Diabetic Mice.Diabetes. 2017 May;66(5):1185-1197. doi: 10.2337/db16-0993. Epub 2017 Feb 28.
988 Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease.PLoS One. 2014 Feb 13;9(2):e88273. doi: 10.1371/journal.pone.0088273. eCollection 2014.
989 Circulating alarin concentrations are high in patients with type 2 diabetes and increased by glucagon-like peptide-1 receptor agonist treatment: An Consort-compliant study.Medicine (Baltimore). 2019 Jul;98(28):e16428. doi: 10.1097/MD.0000000000016428.
990 Pancreatic Histopathology of Human Monogenic Diabetes Due to Causal Variants in KCNJ11, HNF1A, GATA6, and LMNA.J Clin Endocrinol Metab. 2018 Jan 1;103(1):35-45. doi: 10.1210/jc.2017-01159.
991 Analysis of Gene Candidate SNP and Ancestral Origin Associated to Obesity and Postoperative Weight Loss in a Cohort of Obese Patients Undergoing RYGB.Obes Surg. 2017 Jun;27(6):1481-1492. doi: 10.1007/s11695-016-2501-9.
992 The Dual Amylin- and Calcitonin-Receptor Agonist KBP-042 Works as Adjunct to Metformin on Fasting Hyperglycemia and HbA1c in a Rat Model of Type 2 Diabetes.J Pharmacol Exp Ther. 2017 Jul;362(1):24-30. doi: 10.1124/jpet.117.241281. Epub 2017 Apr 24.
993 An SNP-guided microRNA map of fifteen common human disorders identifies a consensus disease phenocode aiming at principal components of the nuclear import pathway.Cell Cycle. 2008 Aug 15;7(16):2570-83. doi: 10.4161/cc.7.16.6524. Epub 2008 Aug 30.
994 Evaluation of human microtubule affinity-regulating kinase 4 inhibitors: fluorescence binding studies, enzyme, and cell assays.J Biomol Struct Dyn. 2017 Nov;35(14):3194-3203. doi: 10.1080/07391102.2016.1249958. Epub 2016 Nov 3.
995 Personalized risk prediction for type 2 diabetes: the potential of genetic risk scores.Genet Med. 2017 Mar;19(3):322-329. doi: 10.1038/gim.2016.103. Epub 2016 Aug 11.
996 Metformin reduces the rate of small intestinal glucose absorption in type 2 diabetes.Diabetes Obes Metab. 2017 Feb;19(2):290-293. doi: 10.1111/dom.12812. Epub 2016 Nov 21.
997 Improvement of quality of life through glycemic control by liraglutide, a GLP-1 analog, in insulin-naive patients with type 2 diabetes mellitus: the PAGE1 study.Diabetol Metab Syndr. 2017 Jan 7;9:3. doi: 10.1186/s13098-016-0202-0. eCollection 2017.
998 Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States.PLoS Genet. 2017 Sep 28;13(9):e1007040. doi: 10.1371/journal.pgen.1007040. eCollection 2017 Sep.
999 Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.Nat Commun. 2017 Nov 27;8(1):1804. doi: 10.1038/s41467-017-01969-4.
1000 Transcriptional profiles of type 2 diabetes in human skeletal muscle reveal insulin resistance, metabolic defects, apoptosis, and molecular signatures of immune activation in response to infections.Biochem Biophys Res Commun. 2017 Jan 8;482(2):282-288. doi: 10.1016/j.bbrc.2016.11.055. Epub 2016 Nov 12.
1001 Downregulation of Rab27A contributes to metformin-induced suppression of breast cancer stem cells.Oncol Lett. 2017 Sep;14(3):2947-2953. doi: 10.3892/ol.2017.6542. Epub 2017 Jul 8.
1002 Eligibility of sodium-glucose co-transporter-2 inhibitors among patients with diabetes mellitus admitted for heart failure.ESC Heart Fail. 2020 Feb;7(1):274-278. doi: 10.1002/ehf2.12528. Epub 2019 Nov 20.
1003 Gene expression in humans with diabetes and prediabetes: what have we learned about diabetes pathophysiology?.Curr Opin Clin Nutr Metab Care. 2004 Jul;7(4):383-90. doi: 10.1097/01.mco.0000134359.23288.72.
1004 Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications.Redox Biol. 2017 Apr;11:637-645. doi: 10.1016/j.redox.2017.01.013. Epub 2017 Jan 16.
1005 Interrupting prolonged sitting in type 2 diabetes: nocturnal persistence of improved glycaemic control.Diabetologia. 2017 Mar;60(3):499-507. doi: 10.1007/s00125-016-4169-z. Epub 2016 Dec 9.
1006 Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice.Am J Hum Genet. 2017 Feb 2;100(2):238-256. doi: 10.1016/j.ajhg.2017.01.011. Epub 2017 Jan 26.
1007 Urinary afamin levels are associated with the progression of diabetic nephropathy.Diabetes Res Clin Pract. 2019 Jan;147:37-46. doi: 10.1016/j.diabres.2018.02.034. Epub 2018 Mar 6.
1008 Higher Levels of ANGPTL5 in the Circulation of Subjects With Obesity and Type 2 Diabetes Are Associated With Insulin Resistance.Front Endocrinol (Lausanne). 2019 Jul 24;10:495. doi: 10.3389/fendo.2019.00495. eCollection 2019.
1009 A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression.Am J Hum Genet. 2018 Apr 5;102(4):620-635. doi: 10.1016/j.ajhg.2018.02.020.
1010 Serum CCN3 levels are increased in type 2 diabetes mellitus and associated with obesity, insulin resistance and inflammation.Clin Chim Acta. 2019 Jul;494:52-57. doi: 10.1016/j.cca.2019.03.006. Epub 2019 Mar 13.
1011 Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome.Autophagy. 2019 Nov;15(11):1882-1898. doi: 10.1080/15548627.2019.1596482. Epub 2019 Apr 6.
1012 High molecular weight adiponectin reduces glucolipotoxicity-induced inflammation and improves lipid metabolism and insulin sensitivity via APPL1-AMPK-GLUT4 regulation in 3T3-L1 adipocytes.Atherosclerosis. 2019 Sep;288:67-75. doi: 10.1016/j.atherosclerosis.2019.07.011. Epub 2019 Jul 12.
1013 The influence of a single nucleotide polymorphism within CNDP1 on susceptibility to diabetic nephropathy in Japanese women with type 2 diabetes.PLoS One. 2013;8(1):e54064. doi: 10.1371/journal.pone.0054064. Epub 2013 Jan 16.
1014 CXCL14 Inhibits Insulin Secretion Independently of CXCR4 or CXCR7 Receptor Activation or cAMP Inhibition.Cell Physiol Biochem. 2019;52(4):879-892. doi: 10.33594/000000061.
1015 Genetic and environmental determinants of dimethylarginines and association with cardiovascular disease in patients with type 2 diabetes.Diabetes Care. 2014;37(3):846-54. doi: 10.2337/dc13-0546. Epub 2013 Nov 1.
1016 Age-Dependent Changes in Glucose Homeostasis in Male Deiodinase Type 2 Knockout Zebrafish.Endocrinology. 2019 Nov 1;160(11):2759-2772. doi: 10.1210/en.2019-00445.
1017 Efficacy of Long-Term Remote Ischemic Conditioning on Vascular and Neuronal Function in Type 2 Diabetes Patients With Peripheral Arterial Disease.J Am Heart Assoc. 2019 Jul 2;8(13):e011779. doi: 10.1161/JAHA.118.011779. Epub 2019 Jun 19.
1018 Association of SNP rs7181866 in the nuclear respiratory factor-2 beta subunit encoding GABPB1 gene with obesity and type-2 diabetes mellitus in South Indian population.Int J Biol Macromol. 2019 Jul 1;132:606-614. doi: 10.1016/j.ijbiomac.2019.03.125. Epub 2019 Mar 20.
1019 Methylation in 3' near region of GC gene and its association with the level of vitamin D binding protein and type 2 diabetes mellitus.Nutr Res. 2018 Jun;54:52-59. doi: 10.1016/j.nutres.2018.03.016. Epub 2018 Apr 6.
1020 Levels and Clinical Significances of Glypican-5 in Urine of Type 2 Diabetic Nephropathy Cases.Iran J Kidney Dis. 2019 May;13(3):173-181.
1021 Association of heat shock protein70-2 (HSP70-2) gene polymorphism with obesity.Ann Hum Biol. 2016 Nov;43(6):542-546. doi: 10.3109/03014460.2015.1119309. Epub 2016 Feb 10.
1022 Common amino acid substitutions in insulin receptor substrate-4 are not associated with Type II diabetes mellitus or insulin resistance.Diabetologia. 1998 Aug;41(8):969-74. doi: 10.1007/s001250051015.
1023 Variability in endocrine cell identity in patients with chronic pancreatitis undergoing islet autotransplantation.Am J Transplant. 2019 May;19(5):1568-1576. doi: 10.1111/ajt.15154. Epub 2018 Nov 28.
1024 The STOP DIABETES study: when prevention works.Acta Diabetol. 2019 May;56(5):501-504. doi: 10.1007/s00592-019-01309-6. Epub 2019 Mar 2.
1025 Association between systemic leptin and neurotensin concentration in adult individuals with and without type 2 diabetes mellitus.J Endocrinol Invest. 2018 Oct;41(10):1159-1163. doi: 10.1007/s40618-018-0845-9. Epub 2018 Feb 7.
1026 Increased OGA Expression and Activity in Leukocytes from Patients with Diabetes: Correlation with Inflammation Markers.Exp Clin Endocrinol Diabetes. 2019 Sep;127(8):517-523. doi: 10.1055/a-0596-7337. Epub 2018 Jun 11.
1027 Osteoglycin and Bone-a Systematic Review.Curr Osteoporos Rep. 2019 Oct;17(5):250-255. doi: 10.1007/s11914-019-00523-z.
1028 PHLPP: a putative cellular target during insulin resistance and type 2 diabetes.J Endocrinol. 2017 Jun;233(3):R185-R198. doi: 10.1530/JOE-17-0081. Epub 2017 Apr 20.
1029 PIK3R1 gene polymorphisms are associated with type 2 diabetes and related features in the Turkish population.Adv Clin Exp Med. 2018 Jul;27(7):921-927. doi: 10.17219/acem/68985.
1030 Association of serum podocalyxin levels with peripheral arterial disease in patients with type 2 diabetes.J Diabetes Complications. 2019 Jul;33(7):495-499. doi: 10.1016/j.jdiacomp.2019.04.003. Epub 2019 Apr 14.
1031 Loss of Response Gene to Complement 32 (RGC-32) in Diabetic Mouse Retina Is Involved in Retinopathy Development.Int J Mol Sci. 2018 Nov 17;19(11):3629. doi: 10.3390/ijms19113629.
1032 Identification of trinucleotide repeat-containing genes in human pancreatic islets.Diabetes. 1996 Feb;45(2):157-64. doi: 10.2337/diab.45.2.157.
1033 Association Analysis of the Reticulon 1 Gene in End-Stage Kidney Disease.Am J Nephrol. 2015;42(4):259-64. doi: 10.1159/000441199. Epub 2015 Oct 24.
1034 A Noncanonical Role for Plasminogen Activator Inhibitor Type 1 in Obesity-Induced Diabetes.Am J Pathol. 2019 Jul;189(7):1413-1422. doi: 10.1016/j.ajpath.2019.04.004. Epub 2019 May 2.
1035 Serum and urinary SOD3 in patients with type 2 diabetes: comparison with early chronic kidney disease patients and association with development of diabetic nephropathy.Am J Physiol Renal Physiol. 2019 Jan 1;316(1):F32-F41. doi: 10.1152/ajprenal.00401.2017. Epub 2018 Oct 10.
1036 Sex-determining region Y-related protein SOX13 is a diabetes autoantigen expressed in pancreatic islets.Diabetes. 2000 Apr;49(4):555-61. doi: 10.2337/diabetes.49.4.555.
1037 Analysis of coding variants identified from exome sequencing resources for association with diabetic and non-diabetic nephropathy in African Americans.Hum Genet. 2014 Jun;133(6):769-779. doi: 10.1007/s00439-013-1415-z. Epub 2014 Jan 3.
1038 High-fat diet and type 2 diabetes induced disruption of the oestrous cycle and alteration of hormonal profiles, but did not affect subpopulations of KNDy neurones in female rats.J Neuroendocrinol. 2018 Nov;30(11):e12651. doi: 10.1111/jne.12651. Epub 2018 Nov 7.
1039 Kruppel-Like Transcription Factor-4 Gene Expression and DNA Methylation Status in Type 2 Diabetes and Diabetic Nephropathy Patients.Arch Med Res. 2019 Apr;50(3):91-97. doi: 10.1016/j.arcmed.2019.05.012. Epub 2019 Jul 24.
1040 Reduced mRNA and Protein Expression Levels of Tet Methylcytosine Dioxygenase 3 in Endothelial Progenitor Cells of Patients of Type 2 Diabetes With Peripheral Artery Disease.Front Immunol. 2018 Dec 6;9:2859. doi: 10.3389/fimmu.2018.02859. eCollection 2018.
1041 Thrombospondin-4 increases with the severity of peripheral arterial disease and is associated with diabetes.Heart Vessels. 2020 Jan;35(1):52-58. doi: 10.1007/s00380-019-01453-7. Epub 2019 Jun 21.
1042 Increased T cell immunoglobulin and mucin domain containing 4 (TIM-4) is negatively correlated with serum concentrations of interleukin-1 in type 2 diabetes.J Diabetes. 2016 Mar;8(2):199-205. doi: 10.1111/1753-0407.12276. Epub 2015 Apr 9.
1043 Sexual Dimorphism of a Genetic Risk Score for Obesity and Related Traits among Chinese Patients with Type 2 Diabetes.Obes Facts. 2019;12(3):328-343. doi: 10.1159/000500490. Epub 2019 Jun 5.
1044 Lysine pathway metabolites and the risk of type 2 diabetes and cardiovascular disease in the PREDIMED study: results from two case-cohort studies.Cardiovasc Diabetol. 2019 Nov 13;18(1):151. doi: 10.1186/s12933-019-0958-2.
1045 Investigating the link of ACAD10 deficiency to type 2 diabetes mellitus.J Inherit Metab Dis. 2018 Jan;41(1):49-57. doi: 10.1007/s10545-017-0013-y. Epub 2017 Jan 24.
1046 DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes.Diabetes. 2019 Jan;68(1):226-234. doi: 10.2337/db18-0857. Epub 2018 Nov 2.
1047 ADAM19: A Novel Target for Metabolic Syndrome in Humans and Mice.Mediators Inflamm. 2017;2017:7281986. doi: 10.1155/2017/7281986. Epub 2017 Feb 7.
1048 The Metalloproteinase ADAM28 Promotes Metabolic Dysfunction in Mice.Int J Mol Sci. 2017 Apr 21;18(4):884. doi: 10.3390/ijms18040884.
1049 Obesity and Co-morbid Conditions Are Associated with Specific Neuropsychiatric Symptoms in Mild Cognitive Impairment.Front Aging Neurosci. 2017 May 29;9:164. doi: 10.3389/fnagi.2017.00164. eCollection 2017.
1050 ADAMTS9 Regulates Skeletal Muscle Insulin Sensitivity Through Extracellular Matrix Alterations.Diabetes. 2019 Mar;68(3):502-514. doi: 10.2337/db18-0418. Epub 2019 Jan 9.
1051 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population.Gene. 2018 Nov 30;677:324-331. doi: 10.1016/j.gene.2018.08.041. Epub 2018 Aug 18.
1052 Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes.Nat Genet. 2018 Feb;50(2):172-174. doi: 10.1038/s41588-017-0022-7. Epub 2018 Jan 8.
1053 Diabetes-linked transcription factor HNF4 regulates metabolism of endogenous methylarginines and -aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2.Sci Rep. 2016 Oct 18;6:35503. doi: 10.1038/srep35503.
1054 Circulating Cell-Free mtDNA Contributes to AIM2 Inflammasome-Mediated Chronic Inflammation in Patients with Type 2 Diabetes.Cells. 2019 Apr 8;8(4):328. doi: 10.3390/cells8040328.
1055 Proteomic profiling of non-obese type 2 diabetic skeletal muscle.Int J Mol Med. 2010 Mar;25(3):445-58. doi: 10.3892/ijmm_00000364.
1056 Shared Genetic Factors Involved in Celiac Disease, Type 2 Diabetes and Anorexia Nervosa Suggest Common Molecular Pathways for Chronic Diseases.PLoS One. 2016 Aug 2;11(8):e0159593. doi: 10.1371/journal.pone.0159593. eCollection 2016.
1057 The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways.Endocrinology. 2009 May;150(5):2098-108. doi: 10.1210/en.2008-0239. Epub 2008 Dec 23.
1058 A Perception on Genome-Wide Genetic Analysis of Metabolic Traits in Arab Populations.Front Endocrinol (Lausanne). 2019 Jan 28;10:8. doi: 10.3389/fendo.2019.00008. eCollection 2019.
1059 Association of serum angiopoietin-like protein 2 with elevated risk of cardiovascular diseases in subjects with type 2 diabetes.J Diabetes Complications. 2019 Nov;33(11):107421. doi: 10.1016/j.jdiacomp.2019.107421. Epub 2019 Aug 22.
1060 Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals.J Biol Chem. 2003 Feb 7;278(6):3514-20. doi: 10.1074/jbc.M204563200. Epub 2002 Nov 26.
1061 Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes.PLoS One. 2015 May 7;10(5):e0126363. doi: 10.1371/journal.pone.0126363. eCollection 2015.
1062 Annexin A6 is highly abundant in monocytes of obese and type 2 diabetic individuals and is downregulated by adiponectin in vitro.Exp Mol Med. 2009 Jul 31;41(7):501-7. doi: 10.3858/emm.2009.41.7.055.
1063 Apolipoprotein-D polymorphism: a genetic marker for obesity and hyperinsulinemia.J Clin Endocrinol Metab. 1994 Aug;79(2):568-70. doi: 10.1210/jcem.79.2.7913935.
1064 Aquaporin 11 rs2276415 variant and progression of chronic kidney disease.Nephrol Dial Transplant. 2019 Jun 1;34(6):970-973. doi: 10.1093/ndt/gfy219.
1065 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.Science. 2007 Jun 1;316(5829):1331-6. doi: 10.1126/science.1142358. Epub 2007 Apr 26.
1066 High levels of circulating endothelial progenitor cells in patients with diabetic retinopathy are positively associated with ARHGAP22 expression.Oncotarget. 2018 Apr 3;9(25):17858-17866. doi: 10.18632/oncotarget.24909. eCollection 2018 Apr 3.
1067 Similar glycaemic control and less hypoglycaemia during active titration after insulin initiation with glargine 300 units/mL and degludec 100 units/mL: A subanalysis of the BRIGHT study.Diabetes Obes Metab. 2020 Mar;22(3):346-354. doi: 10.1111/dom.13901. Epub 2019 Dec 20.
1068 Amino acid signature predictive of incident prediabetes: A case-control study nested within the longitudinal pathobiology of prediabetes in a biracial cohort.Metabolism. 2019 Sep;98:76-83. doi: 10.1016/j.metabol.2019.06.011. Epub 2019 Jun 19.
1069 ARL15 overexpression attenuates high glucose-induced impairment of insulin signaling and oxidative stress in human umbilical vein endothelial cells.Life Sci. 2019 Mar 1;220:127-135. doi: 10.1016/j.lfs.2019.01.030. Epub 2019 Jan 22.
1070 The Loss of ARNT/HIF1 in Male Pancreatic -Cells Is Protective Against High-Fat Diet-Induced Diabetes.Endocrinology. 2019 Dec 1;160(12):2825-2836. doi: 10.1210/en.2018-00936.
1071 Comparing the influence of 2009 versus 2016 ASE/EACVI diastolic function guidelines on the prevalence and echocardiographic characteristics of preclinical diastolic dysfunction (stage B heart failure) in a Hispanic population with type 2 diabetes mellitus.J Diabetes Complications. 2019 Aug;33(8):579-584. doi: 10.1016/j.jdiacomp.2019.04.015. Epub 2019 May 7.
1072 Limited role for SREBP-1c in defective glucose-induced insulin secretion from Zucker diabetic fatty rat islets: a functional and gene profiling analysis.Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E982-94. doi: 10.1152/ajpendo.00067.2006. Epub 2006 Jun 13.
1073 Hamilton rating scale for depression-24 (HAM-D(24)) as a novel predictor for diabetic microvascular complications in type 2 diabetes mellitus patients.Psychiatry Res. 2017 Dec;258:177-183. doi: 10.1016/j.psychres.2017.07.050. Epub 2017 Jul 26.
1074 Detection of differential proteomes associated with the development of type 2 diabetes in the Zucker rat model using the iTRAQ technique.J Proteome Res. 2011 Feb 4;10(2):564-77. doi: 10.1021/pr100759a. Epub 2010 Dec 20.
1075 Nutritional regulation of coupling factor 6, a novel vasoactive and proatherogenic peptide.Nutrition. 2017 May;37:74-78. doi: 10.1016/j.nut.2016.07.017. Epub 2016 Aug 6.
1076 Aliskiren directly improves endothelial progenitor cell function from Type II diabetic patients.Eur J Clin Invest. 2016 Jun;46(6):544-54. doi: 10.1111/eci.12632. Epub 2016 Apr 30.
1077 ATP6V1H facilitates osteogenic differentiation in MC3T3-E1 cells via Akt/GSK3 signaling pathway.Organogenesis. 2019;15(2):43-54. doi: 10.1080/15476278.2019.1633869. Epub 2019 Jul 4.
1078 A novel test for recessive contributions to complex diseases implicates Bardet-Biedl syndrome gene BBS10 in idiopathic type 2 diabetes and obesity.Am J Hum Genet. 2014 Nov 6;95(5):509-20. doi: 10.1016/j.ajhg.2014.09.015. Epub 2014 Oct 16.
1079 The LepR(db/db) mice model for studying glycation in the context of diabetes.Diabetes Metab Res Rev. 2019 Feb;35(2):e3103. doi: 10.1002/dmrr.3103. Epub 2019 Jan 7.
1080 Fabrication of Second Generation Smarter PLGA Based Nanocrystal Carriers for Improvement of Drug Delivery and Therapeutic Efficacy of Gliclazide in Type-2 Diabetes Rat Model.Sci Rep. 2019 Nov 22;9(1):17331. doi: 10.1038/s41598-019-53996-4.
1081 Do genetic variations alter the effects of exercise training on cardiovascular disease and can we identify the candidate variants now or in the future?.J Appl Physiol (1985). 2011 Sep;111(3):916-28. doi: 10.1152/japplphysiol.00153.2011. Epub 2011 May 12.
1082 Comparison of Adherence to Glimepiride/Metformin Sustained Release Once-daily Versus Glimepiride/Metformin Immediate Release BID Fixed-combination Therapy Using the Medication Event Monitoring System in Patients With Type 2 Diabetes.Clin Ther. 2018 May;40(5):752-761.e2. doi: 10.1016/j.clinthera.2018.04.002. Epub 2018 May 3.
1083 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.Nat Commun. 2016 Jan 28;7:10531. doi: 10.1038/ncomms10531.
1084 A gene expression network analysis of the pancreatic islets from lean and obese mice identifies complement 1qlike-3 secreted protein as a regulator of -cell function.Sci Rep. 2019 Jul 12;9(1):10119. doi: 10.1038/s41598-019-46219-3.
1085 CTRP3 is a novel biomarker for diabetic retinopathy and inhibits HGHL-induced VCAM-1 expression in an AMPK-dependent manner.PLoS One. 2017 Jun 20;12(6):e0178253. doi: 10.1371/journal.pone.0178253. eCollection 2017.
1086 Circulating C5L2 gene polymorphism is associated with type 2 diabetes mellitus in Saudi population.Mol Biol Rep. 2013 Nov;40(11):6323-7. doi: 10.1007/s11033-013-2745-6.
1087 Epigenome-wide association study in whole blood on type 2 diabetes among sub-Saharan African individuals: findings from the RODAM study.Int J Epidemiol. 2019 Feb 1;48(1):58-70. doi: 10.1093/ije/dyy171.
1088 Arsenic is more potent than cadmium or manganese in disrupting the INS-1 beta cell microRNA landscape.Arch Toxicol. 2019 Nov;93(11):3099-3109. doi: 10.1007/s00204-019-02574-8. Epub 2019 Sep 25.
1089 Camk2n1 Is a Negative Regulator of Blood Pressure, Left Ventricular Mass, Insulin Sensitivity, and Promotes Adiposity.Hypertension. 2019 Sep;74(3):687-696. doi: 10.1161/HYPERTENSIONAHA.118.12409. Epub 2019 Jul 22.
1090 CAMTA1 T polymorphism is associated with neuropsychological test performance in older adults with cardiovascular disease.Psychogeriatrics. 2011 Sep;11(3):135-40. doi: 10.1111/j.1479-8301.2011.00357.x. Epub 2011 Jun 15.
1091 Hepatic transcriptome and proteome analyses provide new insights into the regulator mechanism of dietary avicularin in diabetic mice.Food Res Int. 2019 Nov;125:108570. doi: 10.1016/j.foodres.2019.108570. Epub 2019 Jul 19.
1092 Characterization of GLUT4 and calpain expression in healthy human skeletal muscle during fasting and refeeding.Acta Physiol (Oxf). 2007 Mar;189(3):233-40. doi: 10.1111/j.1748-1716.2006.01639.x.
1093 CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.Diabetologia. 2016 Sep;59(9):1928-37. doi: 10.1007/s00125-016-4020-6. Epub 2016 Jun 23.
1094 Effect of type 2 diabetes mellitus caveolin-3 K15N mutation on glycometabolism.Exp Ther Med. 2019 Oct;18(4):2531-2539. doi: 10.3892/etm.2019.7840. Epub 2019 Aug 2.
1095 Safety and efficacy of ertugliflozin in Asian patients with type 2 diabetes mellitus inadequately controlled with metformin monotherapy: VERTIS Asia.Diabetes Obes Metab. 2019 Jun;21(6):1474-1482. doi: 10.1111/dom.13681. Epub 2019 Apr 5.
1096 Patient Reported Outcomes following initiation of Glucagon-like peptide-1 Receptor agonists in patients with type 2 Diabetes in a specialist endocrinology practice of the LMC diabetes registry: The PROGRESS-Diabetes study.Diabetes Res Clin Pract. 2019 Oct;156:107820. doi: 10.1016/j.diabres.2019.107820. Epub 2019 Aug 22.
1097 Exercise initiated after the onset of insulin resistance improves trabecular microarchitecture and cortical bone biomechanics of the tibia in hyperphagic Otsuka Long Evans Tokushima Fatty rats.Bone. 2017 Oct;103:188-199. doi: 10.1016/j.bone.2017.07.010. Epub 2017 Jul 12.
1098 Circulating Wnt1-inducible signaling pathway protein-1 (WISP-1/CCN4) is a novel biomarker of adiposity in subjects with type 2 diabetes.J Cell Commun Signal. 2020 Mar;14(1):101-109. doi: 10.1007/s12079-019-00536-4. Epub 2019 Nov 28.
1099 Association between LEKR1-CCNL1 and IGSF21-KLHDC7A gene polymorphisms and diabetic retinopathy of type 2 diabetes mellitus in the Chinese Han population.J Gene Med. 2016 Oct;18(10):282-287. doi: 10.1002/jgm.2926.
1100 A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.Diabetes. 2013 Jan;62(1):291-8. doi: 10.2337/db12-0454. Epub 2012 Sep 6.
1101 Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men.Exp Mol Pathol. 2017 Aug;103(1):1-8. doi: 10.1016/j.yexmp.2017.06.001. Epub 2017 Jun 15.
1102 Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).Diabetes. 2017 May;66(5):1419-1425. doi: 10.2337/db16-1150. Epub 2017 Mar 2.
1103 Investigation of the therapy targets of Yi-Qi-Yang-Yin-Hua-Tan-Qu-Yu recipe on type 2 diabetes by serum proteome labeled with iTRAQ.J Ethnopharmacol. 2018 Oct 5;224:1-14. doi: 10.1016/j.jep.2018.03.027. Epub 2018 Apr 11.
1104 Incident Type 2 Diabetes in OSA and Effect of CPAP Treatment: A Retrospective Clinic Cohort Study.Chest. 2019 Oct;156(4):743-753. doi: 10.1016/j.chest.2019.04.130. Epub 2019 May 22.
1105 Therapeutic Silencing of Centromere Protein X Ameliorates Hyperglycemia in Zebrafish and Mouse Models of Type 2 Diabetes Mellitus.Front Genet. 2019 Jul 29;10:693. doi: 10.3389/fgene.2019.00693. eCollection 2019.
1106 Comparison of therapeutic effects of acarbose and metformin under different -cell function status in Chinese patients with type 2 diabetes.Endocr J. 2019 May 28;66(5):443-450. doi: 10.1507/endocrj.EJ18-0466. Epub 2019 Apr 2.
1107 Noncoding Variations in the Gene Encoding Ceramide Synthase 6 are Associated with Type 2 Diabetes in a Large Indigenous Australian Pedigree.Twin Res Hum Genet. 2019 Apr;22(2):79-87. doi: 10.1017/thg.2019.13. Epub 2019 Apr 23.
1108 A case of 14q11.2 microdeletion with autistic features, severe obesity and facial dysmorphisms suggestive of Wolf-Hirschhorn syndrome.Am J Med Genet A. 2014 Jan;164A(1):190-3. doi: 10.1002/ajmg.a.36200. Epub 2013 Nov 15.
1109 Mitochondrial oxidative stress, endothelial function and metabolic control in patients with type II diabetes and periodontitis: A randomised controlled clinical trial.Int J Cardiol. 2018 Nov 15;271:263-268. doi: 10.1016/j.ijcard.2018.05.019. Epub 2018 Aug 1.
1110 Emerging Mechanisms of GH-Induced Lipolysis and Insulin Resistance.Pediatr Endocrinol Rev. 2019 Sep;17(1):4-16. doi: 10.17458/per.vol17.2019.s.ghlipolysisandinsulinresistance.
1111 4-Hydroxynonenal and 4-Oxononenal Differentially Bind to the Redox Sensor MitoNEET.Chem Res Toxicol. 2019 Jun 17;32(6):977-981. doi: 10.1021/acs.chemrestox.9b00166. Epub 2019 May 29.
1112 Insulin Downregulates the Transcriptional Coregulator CITED2, an Inhibitor of Proangiogenic Function in Endothelial Cells.Diabetes. 2016 Dec;65(12):3680-3690. doi: 10.2337/db16-0001. Epub 2016 Aug 25.
1113 Creatine kinase muscle type specifically interacts with saturated fatty acid- and/or monounsaturated fatty acid-containing phosphatidic acids.Biochem Biophys Res Commun. 2019 Jun 11;513(4):1035-1040. doi: 10.1016/j.bbrc.2019.04.097. Epub 2019 Apr 19.
1114 Statin consumption as a risk factor for developing colorectal cancer: a retrospective case study.World J Surg Oncol. 2017 Dec 16;15(1):222. doi: 10.1186/s12957-017-1287-0.
1115 Epigenetic changes and alteration of Fbn1 and Col3A1 gene expression under hyperglycaemic and hyperinsulinaemic conditions.Biochem J. 2010 Dec 1;432(2):333-41. doi: 10.1042/BJ20100414.
1116 A novel GLP-1/xenin hybrid peptide improves glucose homeostasis, circulating lipids and restores GIP sensitivity in high fat fed mice.Peptides. 2018 Feb;100:202-211. doi: 10.1016/j.peptides.2017.10.015.
1117 Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.Diabetologia. 2016 Apr;59(4):799-812. doi: 10.1007/s00125-015-3852-9. Epub 2016 Jan 11.
1118 Metabolomics reveal mitochondrial and fatty acid metabolism disorders that contribute to the development of DKD in T2DM patients.Mol Biosyst. 2017 Oct 24;13(11):2392-2400. doi: 10.1039/c7mb00167c.
1119 Compromised Neurotrophic and Angiogenic Regenerative Capability during Tendon Healing in a Rat Model of Type-II Diabetes.PLoS One. 2017 Jan 25;12(1):e0170748. doi: 10.1371/journal.pone.0170748. eCollection 2017.
1120 LUTI: a double-function inhibitor isolated from naked flax seeds.Acta Biochim Biophys Sin (Shanghai). 2019 Sep 6;51(10):989-996. doi: 10.1093/abbs/gmz087.
1121 Salivary and serum cystatin SA levels in patients with type 2 diabetes mellitus or diabetic nephropathy.Arch Oral Biol. 2019 Aug;104:67-75. doi: 10.1016/j.archoralbio.2019.05.020. Epub 2019 May 22.
1122 Elevated Serum Uric Acid Is Associated With Greater Risk for Hypertension and Diabetic Kidney Diseases in Obese Adolescents With Type 2 Diabetes: An Observational Analysis From the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study.Diabetes Care. 2019 Jun;42(6):1120-1128. doi: 10.2337/dc18-2147. Epub 2019 Apr 9.
1123 The role of dietary non-heme iron load and peripheral nerve inflammation in the development of peripheral neuropathy (PN) in obese non-diabetic leptin-deficient ob/ob mice.Neurol Res. 2019 Apr;41(4):341-353. doi: 10.1080/01616412.2018.1564191. Epub 2019 Jan 13.
1124 Structural elucidation and bioactivities of a novel arabinogalactan from Coreopsis tinctoria.Carbohydr Polym. 2019 Sep 1;219:219-228. doi: 10.1016/j.carbpol.2019.05.019. Epub 2019 May 7.
1125 Sitagliptin, a dipeptidyl peptidase-4 inhibitor, suppresses CXCL5 and SDF-1 and does not accelerate intestinal neoplasia formation in Apc(Min/+) mice fed a high-fat diet.Oncol Lett. 2017 Oct;14(4):4355-4360. doi: 10.3892/ol.2017.6698. Epub 2017 Aug 1.
1126 Absence of a reductase, NCB5OR, causes insulin-deficient diabetes.Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10750-5. doi: 10.1073/pnas.0404044101. Epub 2004 Jul 9.
1127 Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes.Mol Metab. 2019 Jun;24:98-107. doi: 10.1016/j.molmet.2019.03.004. Epub 2019 Mar 18.
1128 Mitochondrial deoxyribonucleic acid content is specifically decreased in adult, but not fetal, pancreatic islets of the Goto-Kakizaki rat, a genetic model of noninsulin-dependent diabetes.Endocrinology. 1995 Dec;136(12):5623-31. doi: 10.1210/endo.136.12.7588317.
1129 The effect of endurance training with crocin consumption on the levels of MFN2 and DRP1 gene expression and glucose and insulin indices in the muscle tissue of diabetic rats.J Food Biochem. 2020 Feb;44(2):e13125. doi: 10.1111/jfbc.13125. Epub 2019 Dec 17.
1130 Type 2 diabetes impairs odour detection, olfactory memory and olfactory neuroplasticity; effects partly reversed by the DPP-4 inhibitor Linagliptin.Acta Neuropathol Commun. 2018 Feb 23;6(1):14. doi: 10.1186/s40478-018-0517-1.
1131 Metabolic stress activates an ERK/hnRNPK/DDX3X pathway in pancreatic cells.Mol Metab. 2019 Aug;26:45-56. doi: 10.1016/j.molmet.2019.05.009. Epub 2019 May 24.
1132 Superoxide and NADPH oxidase do not modulate skin blood flow in older exercising adults with and without type 2 diabetes.Microvasc Res. 2019 Sep;125:103886. doi: 10.1016/j.mvr.2019.103886. Epub 2019 Jun 12.
1133 The -44 C/G (rs1800972) polymorphism of the -defensin 1 is associated with increased risk of developing type 2 diabetes mellitus.Mol Genet Genomic Med. 2019 Jan;7(1):e00509. doi: 10.1002/mgg3.509. Epub 2018 Dec 13.
1134 Heterogeneity within type II and MODY diabetes.Adv Exp Med Biol. 1985;189:65-87. doi: 10.1007/978-1-4757-1850-8_5.
1135 Ileal interposition coupled with duodenal diverted sleeve gastrectomy versus standard medical treatment in type 2 diabetes mellitus obese patients: long-term results of a case-control study.Surg Endosc. 2019 May;33(5):1553-1563. doi: 10.1007/s00464-018-6443-2. Epub 2018 Sep 17.
1136 Non-invasive vascular assessment in people with type 2 diabetes: Diagnostic performance of Plethysmographic-and-Doppler derived ankle brachial index, toe brachial index, and pulse volume wave analysis for detection of peripheral arterial disease.Prim Care Diabetes. 2020 Jun;14(3):282-289. doi: 10.1016/j.pcd.2019.09.005. Epub 2019 Oct 14.
1137 Chronic Inhibition of Mitochondrial Dihydrolipoamide Dehydrogenase (DLDH) as an Approach to Managing Diabetic Oxidative Stress.Antioxidants (Basel). 2019 Feb 2;8(2):32. doi: 10.3390/antiox8020032.
1138 Risk factors for diabetic macular oedema in type 2 diabetes: A case-control study in a United Kingdom primary care setting.Prim Care Diabetes. 2017 Jun;11(3):288-296. doi: 10.1016/j.pcd.2017.03.002. Epub 2017 Apr 7.
1139 DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation.Sci Rep. 2019 Mar 18;9(1):4772. doi: 10.1038/s41598-019-41244-8.
1140 Increased Circulation and Adipose Tissue Levels of DNAJC27/RBJ in Obesity and Type 2-Diabetes.Front Endocrinol (Lausanne). 2018 Aug 7;9:423. doi: 10.3389/fendo.2018.00423. eCollection 2018.
1141 Effect of selective BET protein inhibitor apabetalone on cardiovascular outcomes in patients with acute coronary syndrome and diabetes: Rationale, design, and baseline characteristics of the BETonMACE trial.Am Heart J. 2019 Nov;217:72-83. doi: 10.1016/j.ahj.2019.08.001. Epub 2019 Aug 9.
1142 Shared and unique components of human population structure and genome-wide signals of positive selection in South Asia.Am J Hum Genet. 2011 Dec 9;89(6):731-44. doi: 10.1016/j.ajhg.2011.11.010.
1143 Safety and Effectiveness of Ipragliflozin for Type 2 Diabetes in Japan: 12-Month Interim Results of the STELLA-LONG TERM Post-Marketing Surveillance Study.Adv Ther. 2019 Apr;36(4):923-949. doi: 10.1007/s12325-019-0895-1. Epub 2019 Feb 14.
1144 Health profile and medication adherence of diabetic patients in the Portuguese population.Prim Care Diabetes. 2019 Oct;13(5):446-451. doi: 10.1016/j.pcd.2019.02.004. Epub 2019 Feb 21.
1145 Cortisol Secretion, Sensitivity, and Activity Are Associated With Hypertension in Postmenopausal Eucortisolemic Women.J Clin Endocrinol Metab. 2019 Oct 1;104(10):4441-4448. doi: 10.1210/jc.2019-00037.
1146 Lack of association between genetic polymorphisms within DUSP12 - ATF6 locus and glucose metabolism related traits in a Chinese population.BMC Med Genet. 2011 Jan 6;12:3. doi: 10.1186/1471-2350-12-3.
1147 Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans.Nat Med. 2019 Nov;25(11):1739-1747. doi: 10.1038/s41591-019-0610-4. Epub 2019 Nov 7.
1148 Identification of variations of gene expression of visceral adipose and renal tissue in type 2 diabetic rats using cDNA representational difference analysis.Chin Med J (Engl). 2003 Apr;116(4):529-33.
1149 Anabolic and Pro-metabolic Functions of CREB-CRTC in Skeletal Muscle: Advantages and Obstacles for Type 2 Diabetes and Cancer Cachexia.Front Endocrinol (Lausanne). 2019 Aug 2;10:535. doi: 10.3389/fendo.2019.00535. eCollection 2019.
1150 Comprehensive transcriptomic analysis indicates brain regional specific alterations in type 2 diabetes.Aging (Albany NY). 2019 Aug 26;11(16):6398-6421. doi: 10.18632/aging.102196. Epub 2019 Aug 26.
1151 Hydrogen Sulfide Prevents Elastin Loss and Attenuates Calcification Induced by High Glucose in Smooth Muscle Cells through Suppression of Stat3/Cathepsin S Signaling Pathway.Int J Mol Sci. 2019 Aug 27;20(17):4202. doi: 10.3390/ijms20174202.
1152 Risk of diabetes associated with fatty acids in the de novo lipogenesis pathway is independent of insulin sensitivity and response: the Insulin Resistance Atherosclerosis Study (IRAS).BMJ Open Diabetes Res Care. 2019 Sep 4;7(1):e000691. doi: 10.1136/bmjdrc-2019-000691. eCollection 2019.
1153 The association of serum and vitreous adropin concentrations with diabetic retinopathy.Ann Clin Biochem. 2019 Mar;56(2):253-258. doi: 10.1177/0004563218820359. Epub 2019 Feb 24.
1154 The role of ERp44 in glucose and lipid metabolism.Arch Biochem Biophys. 2019 Aug 15;671:175-184. doi: 10.1016/j.abb.2019.06.011. Epub 2019 Jul 5.
1155 Novel ERBB receptor feedback inhibitor 1 (ERRFI1) + 808 T/G polymorphism confers protective effect on diabetic nephropathy in a Korean population.Dis Markers. 2013;34(2):113-24. doi: 10.3233/DMA-120949.
1156 Visceral adipose tissue volume is associated with premature atherosclerosis in early type 2 diabetes mellitus independent of traditional risk factors.Atherosclerosis. 2019 Nov;290:87-93. doi: 10.1016/j.atherosclerosis.2019.09.016. Epub 2019 Sep 25.
1157 Two novel susceptibility loci for type 2 diabetes mellitus identified by longitudinal exome-wide association studies in a Japanese population.Genomics. 2019 Jan;111(1):34-42. doi: 10.1016/j.ygeno.2017.12.010. Epub 2017 Dec 19.
1158 Altered expression of WFS1 and NOTCH2 genes associated with diabetic nephropathy in T2DM patients.Diabetes Res Clin Pract. 2018 Jun;140:304-313. doi: 10.1016/j.diabres.2018.03.053. Epub 2018 Apr 4.
1159 Carriers of loss-of-function mutations in EXT display impaired pancreatic beta-cell reserve due to smaller pancreas volume.PLoS One. 2014 Dec 26;9(12):e115662. doi: 10.1371/journal.pone.0115662. eCollection 2014.
1160 Evidence for the Thr79Met polymorphism of the ileal fatty acid binding protein (FABP6) to be associated with type 2 diabetes in obese individuals.Mol Genet Metab. 2009 Dec;98(4):400-5. doi: 10.1016/j.ymgme.2009.08.001. Epub 2009 Aug 11.
1161 Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial.Cardiovasc Diabetol. 2014 Jan 6;13:5. doi: 10.1186/1475-2840-13-5.
1162 FAM3D inhibits glucagon secretion via MKP1-dependent suppression of ERK1/2 signaling.Cell Biol Toxicol. 2017 Oct;33(5):457-466. doi: 10.1007/s10565-017-9387-8. Epub 2017 Feb 28.
1163 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.Nat Genet. 2012 Sep;44(9):981-90. doi: 10.1038/ng.2383. Epub 2012 Aug 12.
1164 Decreased Ficolin-3-mediated Complement Lectin Pathway Activation and Alternative Pathway Amplification During Bacterial Infections in Patients With Type 2 Diabetes Mellitus.Front Immunol. 2019 Mar 20;10:509. doi: 10.3389/fimmu.2019.00509. eCollection 2019.
1165 Abnormal glucose homeostasis and pancreatic islet function in mice with inactivation of the Fem1b gene.Mol Cell Biol. 2005 Aug;25(15):6570-7. doi: 10.1128/MCB.25.15.6570-6577.2005.
1166 Effects of aerobic versus resistance training on serum fetuin-A, fetuin-B, and fibroblast growth factor-21 levels in male diabetic patients.Physiol Int. 2019 Mar 1;106(1):70-80. doi: 10.1556/2060.106.2019.01. Epub 2019 Mar 19.
1167 T2DM inhibition of endothelial miR-342-3p facilitates angiogenic dysfunction via repression of FGF11 signaling.Biochem Biophys Res Commun. 2018 Sep 3;503(1):71-78. doi: 10.1016/j.bbrc.2018.05.179. Epub 2018 Jun 7.
1168 Overexpression of Hepassocin in Diabetic Patients with Nonalcoholic Fatty Liver Disease May Facilitate Increased Hepatic Lipid Accumulation.Endocr Metab Immune Disord Drug Targets. 2019;19(2):185-188. doi: 10.2174/1871530318666180716100543.
1169 Fibronectin Type III Domain Containing 4 attenuates hyperlipidemia-induced insulin resistance via suppression of inflammation and ER stress through HO-1 expression in adipocytes.Biochem Biophys Res Commun. 2018 Jul 7;502(1):129-136. doi: 10.1016/j.bbrc.2018.05.133. Epub 2018 May 24.
1170 Association between Irisin, hs-CRP, and Metabolic Status in Children and Adolescents with Type 2 Diabetes Mellitus.Mediators Inflamm. 2019 Mar 20;2019:6737318. doi: 10.1155/2019/6737318. eCollection 2019.
1171 Plasma Copeptin and Risk of Lower-Extremity Amputation in Type 1 and Type 2 Diabetes.Diabetes Care. 2019 Dec;42(12):2290-2297. doi: 10.2337/dc19-1062. Epub 2019 Oct 3.
1172 Longevity-Associated Forkhead Box O3 (FOXO3) Single Nucleotide Polymorphisms are Associated with Type 2 Diabetes Mellitus in Chinese Elderly Women.Med Sci Monit. 2019 Apr 22;25:2966-2975. doi: 10.12659/MSM.913788.
1173 Upregulation of Circulating Cardiomyocyte-Enriched miR-1 and miR-133 Associate with the Risk of Coronary Artery Disease in Type 2 Diabetes Patients and Serve as Potential Biomarkers.J Cardiovasc Transl Res. 2019 Aug;12(4):347-357. doi: 10.1007/s12265-018-9857-2. Epub 2019 Jan 4.
1174 A genome-wide search for type 2 diabetes susceptibility genes in an extended Arab family.Ann Hum Genet. 2013 Nov;77(6):488-503. doi: 10.1111/ahg.12036. Epub 2013 Aug 13.
1175 Evaluating the burden of poor glycemic control associated with therapeutic inertia in patients with type 2 diabetes in the UK.J Med Econ. 2020 Jan;23(1):98-105. doi: 10.1080/13696998.2019.1645018. Epub 2019 Aug 2.
1176 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.Nat Genet. 2011 Dec 11;44(1):67-72. doi: 10.1038/ng.1019.
1177 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.Nat Genet. 2011 Aug 28;43(10):984-9. doi: 10.1038/ng.921.
1178 Circulating GDF11 levels are decreased with age but are unchanged with obesity and type 2 diabetes.Aging (Albany NY). 2019 Mar 21;11(6):1733-1744. doi: 10.18632/aging.101865.
1179 Brain education-based meditation for patients with hypertension and/or type 2 diabetes: A pilot randomized controlled trial.Medicine (Baltimore). 2019 May;98(19):e15574. doi: 10.1097/MD.0000000000015574.
1180 Type 2 diabetes-related genetic risk scores associated with variations in fasting plasma glucose and development of impaired glucose homeostasis in the prospective DESIR study.Diabetologia. 2014 Aug;57(8):1601-10. doi: 10.1007/s00125-014-3277-x. Epub 2014 Jun 4.
1181 Intestinal fatty acid binding protein Ala54Thr polymorphism is associated with peripheral atherosclerosis combined with type 2 diabetes mellitus.J Diabetes. 2017 Sep;9(9):821-826. doi: 10.1111/1753-0407.12496. Epub 2016 Dec 9.
1182 Glypican-4 is increased in human subjects with impaired glucose tolerance and decreased in patients with newly diagnosed type 2 diabetes.Acta Diabetol. 2014 Dec;51(6):981-90. doi: 10.1007/s00592-014-0652-5. Epub 2014 Sep 21.
1183 GPR142 prompts glucagon-like Peptide-1 release from islets to improve cell function.Mol Metab. 2018 May;11:205-211. doi: 10.1016/j.molmet.2018.02.008. Epub 2018 Feb 23.
1184 GPRC5B a putative glutamate-receptor candidate is negative modulator of insulin secretion.Biochem Biophys Res Commun. 2013 Nov 22;441(3):643-8.
1185 G protein pathway suppressor 2 (GPS2) links inflammation and cholesterol efflux by controlling lipopolysaccharide-induced ATP-binding cassette transporter A1 expression in macrophages.FASEB J. 2019 Feb;33(2):1631-1643. doi: 10.1096/fj.201801123R. Epub 2018 Aug 28.
1186 Hepatic ALT isoenzymes are elevated in gluconeogenic conditions including diabetes and suppressed by insulin at the protein level.Diabetes Metab Res Rev. 2015 Sep;31(6):562-71. doi: 10.1002/dmrr.2655. Epub 2015 Jun 17.
1187 Epigenetic Alterations in Human Liver From Subjects With Type 2 Diabetes in Parallel With Reduced Folate Levels.J Clin Endocrinol Metab. 2015 Nov;100(11):E1491-501. doi: 10.1210/jc.2015-3204. Epub 2015 Sep 29.
1188 Translocase of inner mitochondrial membrane 44 alters the mitochondrial fusion and fission dynamics and protects from type 2 diabetes.Metabolism. 2015 Jun;64(6):677-88. doi: 10.1016/j.metabol.2015.02.004. Epub 2015 Feb 23.
1189 Attenuation of metabolic syndrome in the ob/ob mouse model by resistant starch intervention is dose dependent.Food Funct. 2019 Dec 11;10(12):7940-7951. doi: 10.1039/c9fo01771b.
1190 Serum kidney injury molecule 1 and (2)-microglobulin perform as well as larger biomarker panels for prediction of rapid decline in renal function in type 2 diabetes.Diabetologia. 2019 Jan;62(1):156-168. doi: 10.1007/s00125-018-4741-9. Epub 2018 Oct 5.
1191 Subsets of Finns with high HDL to total cholesterol ratio show evidence for linkage to type 2 diabetes on chromosome 6q.Hum Hered. 2007;63(1):17-25. doi: 10.1159/000097927. Epub 2006 Dec 14.
1192 HLA-DRB1 reduces the risk of type 2 diabetes mellitus by increased insulin secretion.Diabetologia. 2011 Jul;54(7):1684-92. doi: 10.1007/s00125-011-2122-8. Epub 2011 Apr 12.
1193 Altered intragenic DNA methylation of HOOK2 gene in adipose tissue from individuals with obesity and type 2 diabetes.PLoS One. 2017 Dec 11;12(12):e0189153. doi: 10.1371/journal.pone.0189153. eCollection 2017.
1194 Physical Interactions and Expression Quantitative Traits Loci Identify Regulatory Connections for Obesity and Type 2 Diabetes Associated SNPs.Front Genet. 2017 Oct 13;8:150. doi: 10.3389/fgene.2017.00150. eCollection 2017.
1195 Impact of hepatic HSP72 on insulin signaling.Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E305-E318. doi: 10.1152/ajpendo.00215.2018. Epub 2018 Dec 11.
1196 Association of polymorphism in heat shock protein 70 genes with type 2 diabetes in Bangladeshi population.Mol Genet Genomic Med. 2020 Feb;8(2):e1073. doi: 10.1002/mgg3.1073. Epub 2019 Dec 9.
1197 PAPP-A activity is increased in cerebrospinal fluid from patients with diabetic polyneuropathy and correlates with peripheral nerve impairment.Growth Horm IGF Res. 2019 Oct-Dec;48-49:53-59. doi: 10.1016/j.ghir.2019.10.001. Epub 2019 Oct 17.
1198 Levels of cytokines and GADA in type I and II diabetic patients.Prim Care Diabetes. 2020 Feb;14(1):61-67. doi: 10.1016/j.pcd.2019.03.008. Epub 2019 Apr 20.
1199 SHIPping out diabetes-Metformin, an old friend among new SHIP2 inhibitors.Acta Physiol (Oxf). 2020 Jan;228(1):e13349. doi: 10.1111/apha.13349. Epub 2019 Aug 12.
1200 Type 2 diabetes increases the risk of hospital admission for heart failure and reduces the risk of in hospital mortality in Spain (2001-2015).Eur J Intern Med. 2019 Jan;59:53-59. doi: 10.1016/j.ejim.2018.08.011. Epub 2018 Aug 22.
1201 Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.PLoS Genet. 2014 Aug 7;10(8):e1004517. doi: 10.1371/journal.pgen.1004517. eCollection 2014 Aug.
1202 A low-calorie diet with or without interval exercise training improves adiposopathy in obese women.Appl Physiol Nutr Metab. 2019 Oct;44(10):1057-1064. doi: 10.1139/apnm-2018-0717. Epub 2019 Feb 20.
1203 CD39 expression on Treg and Th17 cells is associated with metabolic factors in patients with type 2 diabetes.Hum Immunol. 2015 Sep;76(9):622-30. doi: 10.1016/j.humimm.2015.09.007. Epub 2015 Sep 18.
1204 MiR-128-3p accelerates cardiovascular calcification and insulin resistance through ISL1-dependent Wnt pathway in type 2 diabetes mellitus rats.J Cell Physiol. 2019 Apr;234(4):4997-5010. doi: 10.1002/jcp.27300. Epub 2018 Oct 20.
1205 Evaluation of platelet reactivity during combined antiplatelet therapy in patients with stable coronary artery disease in relation to diabetes type 2 and the GPIIB/IIIA receptor gene polymorphism.J Physiol Pharmacol. 2019 Apr;70(2). doi: 10.26402/jpp.2019.2.01. Epub 2019 Jul 22.
1206 Effects of Type 2 Diabetes Mellitus on Gene Expressions of Mouse Meibomian Glands.Curr Eye Res. 2020 Jan;45(1):72-80. doi: 10.1080/02713683.2019.1656750. Epub 2019 Aug 27.
1207 Cardioprotective properties of omentin-1 in type 2 diabetes: evidence from clinical and in vitro studies. PLoS One. 2013;8(3):e59697. doi: 10.1371/journal.pone.0059697. Epub 2013 Mar 29.
1208 Prevalence and clinical characteristics of mitochondrial tRNA leu(UUR) mt 3243 A-->G and ND-1 gene mt 3316 G-->A mutations in Chinese patients with type 2 diabetes.Chin Med J (Engl). 2001 Nov;114(11):1205-7.
1209 Divergent patterns of genic copy number variation in KCNIP1 gene reveal risk locus of type 2 diabetes in Chinese population.Endocr J. 2018 May 28;65(5):537-545. doi: 10.1507/endocrj.EJ17-0496. Epub 2018 Feb 27.
1210 Replication study for the association of a single-nucleotide polymorphism, rs3746876, within KCNJ15, with susceptibility to type 2 diabetes in a Japanese population.J Hum Genet. 2013 Jul;58(7):490-3. doi: 10.1038/jhg.2013.28. Epub 2013 Apr 18.
1211 Impaired Ca2+-dependent activation of large-conductance Ca2+-activated K+ channels in the coronary artery smooth muscle cells of Zucker Diabetic Fatty rats.Biophys J. 2008 Dec;95(11):5165-77. doi: 10.1529/biophysj.108.138339. Epub 2008 Sep 12.
1212 No clinical utility of common polymorphisms in IGF1, IRS1, GCKR, PPARG, GCK1 and KCTD1 genes previously associated with insulin resistance in overweight children from Romania and Moldova.J Pediatr Endocrinol Metab. 2019 Jan 28;32(1):33-39. doi: 10.1515/jpem-2018-0288.
1213 Oxymatrine ameliorates insulin resistance in rats with type 2 diabetes by regulating the expression of KSRP, PETN, and AKT in the liver.J Cell Biochem. 2019 Sep;120(9):16185-16194. doi: 10.1002/jcb.28898. Epub 2019 May 14.
1214 Novel KIF6 polymorphism increases susceptibility to type 2 diabetes mellitus and coronary heart disease in Han Chinese men.J Diabetes Res. 2014;2014:871439. doi: 10.1155/2014/871439. Epub 2014 Dec 31.
1215 FGF23 and Klotho Levels are Independently Associated with Diabetic Foot Syndrome in Type 2 Diabetes Mellitus.J Clin Med. 2019 Apr 3;8(4):448. doi: 10.3390/jcm8040448.
1216 KLF10 transcription factor regulates hepatic glucose metabolism in mice.Diabetologia. 2017 Dec;60(12):2443-2452. doi: 10.1007/s00125-017-4412-2. Epub 2017 Aug 23.
1217 DNA methylation of the Klf14 gene region in whole blood cells provides prediction for the chronic inflammation in the adipose tissue.Biochem Biophys Res Commun. 2018 Mar 11;497(3):908-915. doi: 10.1016/j.bbrc.2017.12.104. Epub 2018 Feb 6.
1218 Inhibition of Sodium Glucose Cotransporter 2 Attenuates the Dysregulation of Kelch-Like 3 and NaCl Cotransporter in Obese Diabetic Mice.J Am Soc Nephrol. 2019 May;30(5):782-794. doi: 10.1681/ASN.2018070703. Epub 2019 Mar 26.
1219 Elevated serum cytokeratin-18 concentration in patients with type 2 diabetes mellitus and non-alcoholic fatty liver disease.Ann Clin Biochem. 2019 Jan;56(1):141-147. doi: 10.1177/0004563218796259. Epub 2018 Aug 27.
1220 Metabolic risk profiles in diabetes stratified according to age at onset, islet autoimmunity and fasting C-peptide.Diabetes Res Clin Pract. 2017 Dec;134:62-71. doi: 10.1016/j.diabres.2017.09.014. Epub 2017 Oct 5.
1221 Urinary Neutrophil Gelatinase-Associated Lipocalin Is Complementary to Albuminuria in Diagnosis of Early-Stage Diabetic Kidney Disease in Type 2 Diabetes.Biomed Res Int. 2017;2017:4691389. doi: 10.1155/2017/4691389. Epub 2017 Aug 6.
1222 Circulating LECT2 levels in newly diagnosed type 2 diabetes mellitus and their association with metabolic parameters: An observational study.Medicine (Baltimore). 2018 Apr;97(15):e0354. doi: 10.1097/MD.0000000000010354.
1223 A genetic variant in LINGO2 contributes to the risk of gestational diabetes mellitus in a Chinese population.J Cell Physiol. 2019 May;234(5):7012-7018. doi: 10.1002/jcp.27454. Epub 2018 Nov 13.
1224 Association of APOB and LIPC polymorphisms with type 2 diabetes in Chinese Han population.Gene. 2018 Sep 25;672:150-155. doi: 10.1016/j.gene.2018.06.010. Epub 2018 Jun 5.
1225 Design of a randomised controlled trial of the effects of empagliflozin on myocardial perfusion, function and metabolism in type 2 diabetes patients at high cardiovascular risk (the SIMPLE trial).BMJ Open. 2019 Nov 27;9(11):e029098. doi: 10.1136/bmjopen-2019-029098.
1226 LRG1 Promotes Diabetic Kidney Disease Progression by Enhancing TGF--Induced Angiogenesis.J Am Soc Nephrol. 2019 Apr;30(4):546-562. doi: 10.1681/ASN.2018060599. Epub 2019 Mar 11.
1227 The roles of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in malignancy of human endometrial cancer cells.Oncotarget. 2016 May 10;7(19):27735-52. doi: 10.18632/oncotarget.8408.
1228 Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study.Eur J Hum Genet. 2009 Aug;17(8):1056-62. doi: 10.1038/ejhg.2009.4. Epub 2009 Feb 11.
1229 Enhanced autophagy plays a cardinal role in mitochondrial dysfunction in type 2 diabetic Goto-Kakizaki (GK) rats: ameliorating effects of (-)-epigallocatechin-3-gallate.J Nutr Biochem. 2012 Jul;23(7):716-24. doi: 10.1016/j.jnutbio.2011.03.014. Epub 2011 Aug 4.
1230 The -822G/A polymorphism in the promoter region of the MAP4K5 gene is associated with reduced risk of type 2 diabetes in Chinese Hans from Shanghai.J Hum Genet. 2006;51(7):605-10. doi: 10.1007/s10038-006-0402-9. Epub 2006 May 13.
1231 Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in individuals with alcohol-related cirrhosis.Am J Gastroenterol. 2018 Oct;113(10):1475-1483. doi: 10.1038/s41395-018-0041-8. Epub 2018 Mar 13.
1232 Non-pharmacological interventions for cognition in patients with Type 2 diabetes mellitus: a systematic review.QJM. 2020 Mar 1;113(3):155-161. doi: 10.1093/qjmed/hcz053.
1233 MED25 is a mediator component of HNF4-driven transcription leading to insulin secretion in pancreatic beta-cells.PLoS One. 2012;7(8):e44007. doi: 10.1371/journal.pone.0044007. Epub 2012 Aug 30.
1234 Exercise increases hyper-acetylation of histones on the Cis-element of NRF-1 binding to the Mef2a promoter: Implications on type 2 diabetes.Biochem Biophys Res Commun. 2017 Apr 22;486(1):83-87. doi: 10.1016/j.bbrc.2017.03.002. Epub 2017 Mar 2.
1235 Effects of exercise training on inflammasome-related mediators and their associations to glucometabolic variables in patients with combined coronary artery disease and type 2 diabetes mellitus: Sub-study of a randomized control trial.Diab Vasc Dis Res. 2019 Jul;16(4):360-368. doi: 10.1177/1479164119836922. Epub 2019 Apr 3.
1236 Serum Meteorin-like protein levels decreased in patients newly diagnosed with type 2 diabetes.Diabetes Res Clin Pract. 2018 Jan;135:7-10. doi: 10.1016/j.diabres.2017.10.005. Epub 2017 Oct 31.
1237 METTL3 inhibits hepatic insulin sensitivity via N6-methyladenosine modification of Fasn mRNA and promoting fatty acid metabolism.Biochem Biophys Res Commun. 2019 Oct 8;518(1):120-126. doi: 10.1016/j.bbrc.2019.08.018. Epub 2019 Aug 10.
1238 MHC class I chain-related gene a alleles distinguish malnutrition-modulated diabetes, insulin-dependent diabetes, and non-insulin- dependent diabetes mellitus patients from eastern India.Ann N Y Acad Sci. 2002 Apr;958:341-4. doi: 10.1111/j.1749-6632.2002.tb03001.x.
1239 Design and validation of a scoring model for differential diagnosis of diabetic nephropathy and nondiabetic renal diseases in type 2 diabetic patients.J Diabetes. 2020 Mar;12(3):237-246. doi: 10.1111/1753-0407.12994. Epub 2019 Dec 2.
1240 Glucose-Sensing Transcription Factor MondoA/ChREBP as Targets for Type 2 Diabetes: Opportunities and Challenges.Int J Mol Sci. 2019 Oct 16;20(20):5132. doi: 10.3390/ijms20205132.
1241 miRNA-mediated relationships between Cis-SNP genotypes and transcript intensities in lymphocyte cell lines.PLoS One. 2012;7(2):e31429. doi: 10.1371/journal.pone.0031429. Epub 2012 Feb 14.
1242 Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.Diabetologia. 2019 Dec;62(12):2273-2286. doi: 10.1007/s00125-019-05008-3. Epub 2019 Oct 17.
1243 Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer.Oncotarget. 2016 Aug 2;7(31):50490-50506. doi: 10.18632/oncotarget.10466.
1244 Haplotype synthesis analysis reveals functional variants underlying known genome-wide associated susceptibility loci.Bioinformatics. 2016 Jul 15;32(14):2136-42. doi: 10.1093/bioinformatics/btw125. Epub 2016 Mar 21.
1245 Chronic Osteomyelitis Increases the Incidence of Type 2 Diabetes in Humans and Mice.Int J Biol Sci. 2017 Sep 5;13(9):1192-1202. doi: 10.7150/ijbs.21379. eCollection 2017.
1246 Association of serum levels of p,p'- Dichlorodiphenyldichloroethylene (DDE) with type 2 diabetes in African American and Caucasian adult men from agricultural (Delta) and non-agricultural (non-Delta) regions of Mississippi.J Toxicol Environ Health A. 2019;82(6):387-400. doi: 10.1080/15287394.2019.1610678. Epub 2019 May 7.
1247 A single non-synonymous NCOA5 variation in type 2 diabetic patients with hepatocellular carcinoma impairs the function of NCOA5 in cell cycle regulation.Cancer Lett. 2017 Apr 10;391:152-161. doi: 10.1016/j.canlet.2017.01.028. Epub 2017 Jan 27.
1248 Regulation of insulin secretion and beta-cell mass by activating signal cointegrator 2.Mol Cell Biol. 2006 Jun;26(12):4553-63. doi: 10.1128/MCB.01412-05.
1249 Role of NCoR1 in mitochondrial function and energy metabolism.Cell Biol Int. 2018 Jun;42(6):734-741. doi: 10.1002/cbin.10973. Epub 2018 May 8.
1250 Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration.Cell Metab. 2010 Dec 1;12(6):643-53. doi: 10.1016/j.cmet.2010.11.007.
1251 NCS-1 Deficiency Is Associated With Obesity and Diabetes Type 2 in Mice.Front Mol Neurosci. 2019 Apr 3;12:78. doi: 10.3389/fnmol.2019.00078. eCollection 2019.
1252 Novel mutations of mitochondrial DNA associated with type 2 diabetes in Chinese Han population.Tohoku J Exp Med. 2008 Aug;215(4):377-84. doi: 10.1620/tjem.215.377.
1253 The global prevalence of tobacco use in type 2 diabetes mellitus patients: A systematic review and meta-analysis.Diabetes Res Clin Pract. 2019 Aug;154:52-65. doi: 10.1016/j.diabres.2019.05.035. Epub 2019 Jun 14.
1254 Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility.Eur J Hum Genet. 2016 Aug;24(8):1175-80. doi: 10.1038/ejhg.2016.17. Epub 2016 May 18.
1255 Effects of Genetic Variants of Nuclear Receptor Y on the Risk of Type 2 Diabetes Mellitus.J Diabetes Res. 2019 May 7;2019:4902301. doi: 10.1155/2019/4902301. eCollection 2019.
1256 Type 2 Diabetes: how informed are the general public? A cross-sectional study investigating disease awareness and barriers to communicating knowledge in high-risk populations in London.BMC Public Health. 2019 Jan 31;19(1):138. doi: 10.1186/s12889-019-6460-7.
1257 NIPA2 regulates osteoblast function via its effect on apoptosis pathways in type 2 diabetes osteoporosis.Biochem Biophys Res Commun. 2019 Jun 11;513(4):883-890. doi: 10.1016/j.bbrc.2019.04.030. Epub 2019 Apr 16.
1258 The low levels of bone morphogenic protein-4 and its antagonist noggin in type 2 diabetes.Hormones (Athens). 2018 Jun;17(2):247-253. doi: 10.1007/s42000-018-0041-5. Epub 2018 Jun 26.
1259 Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain.EBioMedicine. 2019 Sep;47:352-364. doi: 10.1016/j.ebiom.2019.08.033. Epub 2019 Aug 28.
1260 The Extending Spectrum of NPC1-Related Human Disorders: From Niemann-Pick C1 Disease to Obesity.Endocr Rev. 2018 Apr 1;39(2):192-220. doi: 10.1210/er.2017-00176.
1261 Metformin ameliorates podocyte damage by restoring renal tissue nephrin expression in type 2 diabetic rats.J Diabetes. 2017 May;9(5):510-517. doi: 10.1111/1753-0407.12437. Epub 2016 Sep 12.
1262 Genetic Analysis of the Atrial Natriuretic Peptide Gene Polymorphisms among Essential Hypertensive Patients in Malaysia.Biomed Res Int. 2016;2016:6712529. doi: 10.1155/2016/6712529. Epub 2016 Jun 20.
1263 Prescribing for people with type 2 diabetes and renal impairment in Australian general practice: A national cross sectional study.Prim Care Diabetes. 2019 Apr;13(2):113-121. doi: 10.1016/j.pcd.2018.09.001. Epub 2018 Sep 24.
1264 Anti-inflammatory and renal protective effect of gingerol in high-fat diet/streptozotocin-induced diabetic rats via inflammatory mechanism.Inflammopharmacology. 2019 Dec;27(6):1243-1254. doi: 10.1007/s10787-019-00569-6. Epub 2019 Mar 2.
1265 Conformational analysis and invitro immunomodulatory and insulinotropic properties of the frog skin host-defense peptide rhinophrynin-27 and selected analogs.Biochimie. 2019 Dec;167:198-206. doi: 10.1016/j.biochi.2019.10.007. Epub 2019 Oct 19.
1266 Lupin seed hydrolysate promotes G-protein-coupled receptor, intracellular Ca(2+) and enhanced glycolytic metabolism-mediated insulin secretion from BRIN-BD11 pancreatic beta cells.Mol Cell Endocrinol. 2019 Jan 15;480:83-96. doi: 10.1016/j.mce.2018.10.015. Epub 2018 Oct 19.
1267 Nupr1 deletion protects against glucose intolerance by increasing beta cell mass.Diabetologia. 2013 Nov;56(11):2477-86. doi: 10.1007/s00125-013-3006-x. Epub 2013 Jul 31.
1268 Impact of Active Antihyperglycemic Components as Herbal Therapy for Preventive Health Care Management of Diabetes.Curr Mol Med. 2019;19(1):12-19. doi: 10.2174/1566524019666190219124301.
1269 Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity.Mol Metab. 2018 May;11:160-177. doi: 10.1016/j.molmet.2018.02.010. Epub 2018 Feb 24.
1270 Haptoglobin 2-2 genotype and the risk of coronary artery disease in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC).J Diabetes Complications. 2016 Nov-Dec;30(8):1577-1584. doi: 10.1016/j.jdiacomp.2016.07.014. Epub 2016 Jul 25.
1271 T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility.Sci Rep. 2014 Dec 8;4:7351. doi: 10.1038/srep07351.
1272 Lower succinyl-CoA:3-ketoacid-CoA transferase (SCOT) and ATP citrate lyase in pancreatic islets of a rat model of type 2 diabetes: knockdown of SCOT inhibits insulin release in rat insulinoma cells.Arch Biochem Biophys. 2010 Jul;499(1-2):62-8. doi: 10.1016/j.abb.2010.05.007. Epub 2010 May 9.
1273 Genetic analysis of advanced glycation end products in the DHS MIND study.Gene. 2016 Jun 15;584(2):173-9. doi: 10.1016/j.gene.2016.02.029. Epub 2016 Feb 23.
1274 Pannexin-1 mediated ATP release in adipocytes is sensitive to glucose and insulin and modulates lipolysis and macrophage migration.Acta Physiol (Oxf). 2020 Feb;228(2):e13360. doi: 10.1111/apha.13360. Epub 2019 Oct 14.
1275 Studies of the variability of the hepatocyte nuclear factor-1beta (HNF-1beta / TCF2) and the dimerization cofactor of HNF-1 (DcoH / PCBD) genes in relation to type 2 diabetes mellitus and beta-cell function.Hum Mutat. 2001 Oct;18(4):356-7. doi: 10.1002/humu.1201.
1276 Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.PLoS Genet. 2011 Apr;7(4):e1001363. doi: 10.1371/journal.pgen.1001363. Epub 2011 Apr 7.
1277 The expression of genes involved in jejunal lipogenesis and lipoprotein synthesis is altered in morbidly obese subjects with insulin resistance.Lab Invest. 2015 Dec;95(12):1409-17. doi: 10.1038/labinvest.2015.115. Epub 2015 Sep 14.
1278 Polymorphisms in PDLIM5 gene are associated with alcohol dependence, type 2 diabetes, and hypertension.J Psychiatr Res. 2017 Jan;84:27-34. doi: 10.1016/j.jpsychires.2016.09.015. Epub 2016 Sep 17.
1279 DNA methylation of candidate genes in peripheral blood from patients with type 2 diabetes or the metabolic syndrome.PLoS One. 2017 Jul 20;12(7):e0180955. doi: 10.1371/journal.pone.0180955. eCollection 2017.
1280 Circadian clock genes and myocardial infarction in patients with type 2 diabetes mellitus.Gene. 2019 Jun 15;701:98-103. doi: 10.1016/j.gene.2019.03.038. Epub 2019 Mar 21.
1281 Insulin resistance and impaired insulin secretion due to phosphofructo-1-kinase-deficiency in humans.J Mol Med (Berl). 1999 Jan;77(1):96-103. doi: 10.1007/s001090050311.
1282 Antagonistic Activity of Naphthoquinone-Based Hybrids toward Amyloids Associated with Alzheimer's Disease and Type-2 Diabetes.ACS Chem Neurosci. 2019 Aug 21;10(8):3510-3520. doi: 10.1021/acschemneuro.9b00123. Epub 2019 Jul 8.
1283 Blood-Based DNA Methylation Biomarkers for Type 2 Diabetes: Potential for Clinical Applications.Front Endocrinol (Lausanne). 2018 Dec 4;9:744. doi: 10.3389/fendo.2018.00744. eCollection 2018.
1284 The lipid phosphatase SHIP2 controls insulin sensitivity.Nature. 2001 Jan 4;409(6816):92-7. doi: 10.1038/35051094.
1285 Susceptible gene of stasis-stagnation constitution from genome-wide association study related to cardiovascular disturbance and possible regulated traditional Chinese medicine.BMC Complement Altern Med. 2015 Jul 14;15:229. doi: 10.1186/s12906-015-0761-x.
1286 First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes.PLoS One. 2015 Mar 11;10(3):e0119333. doi: 10.1371/journal.pone.0119333. eCollection 2015.
1287 MiR-17 family-mediated regulation of Pknox1 influences hepatic steatosis and insulin signaling.J Cell Mol Med. 2018 Dec;22(12):6167-6175. doi: 10.1111/jcmm.13902. Epub 2018 Oct 19.
1288 Genetic variants of PLA2G6 are associated with Type 2 diabetes mellitus and triglyceride levels in a Chinese population.Diabet Med. 2015 Feb;32(2):280-6. doi: 10.1111/dme.12587. Epub 2014 Oct 11.
1289 Type 2 diabetes is associated with suppression of autophagy and lipid accumulation in -cells.J Cell Mol Med. 2019 Apr;23(4):2890-2900. doi: 10.1111/jcmm.14172. Epub 2019 Feb 1.
1290 Optical Coherence Tomographic Angiography in Type 2 Diabetes and Diabetic Retinopathy.JAMA Ophthalmol. 2017 Apr 1;135(4):306-312. doi: 10.1001/jamaophthalmol.2016.5877.
1291 Association of pigment epithelium derived factor with von Willebrand factor and plasminogen activator inhibitor 1 in patients with type 2 diabetes.Physiol Res. 2019 Jun 30;68(3):409-418. doi: 10.33549/physiolres.934013. Epub 2019 Mar 22.
1292 Genetic polymorphisms associated with pediatric-onset type 2 diabetes: A family-based transmission disequilibrium test and case-control study.Pediatr Diabetes. 2019 May;20(3):239-245. doi: 10.1111/pedi.12818. Epub 2019 Feb 6.
1293 Caffeine Impact on Metabolic Syndrome Components Is Modulated by a CYP1A2 Variant.Ann Nutr Metab. 2016;68(1):1-11. doi: 10.1159/000441481. Epub 2015 Nov 21.
1294 Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes.PLoS One. 2019 Jan 10;14(1):e0210114. doi: 10.1371/journal.pone.0210114. eCollection 2019.
1295 PPP1R3C mediates metformin-inhibited hepatic gluconeogenesis.Metabolism. 2019 Sep;98:62-75. doi: 10.1016/j.metabol.2019.06.002. Epub 2019 Jun 8.
1296 Expression of epicardial adipose tissue thermogenic genes in patients with reduced and preserved ejection fraction heart failure.Int J Med Sci. 2017 Jul 20;14(9):891-895. doi: 10.7150/ijms.19854. eCollection 2017.
1297 Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.Genomics. 2010 Oct;96(4):211-9. doi: 10.1016/j.ygeno.2010.07.006. Epub 2010 Jul 30.
1298 Haplotype structures and large-scale association testing of the 5' AMP-activated protein kinase genes PRKAA2, PRKAB1, and PRKAB2 [corrected] with type 2 diabetes.Diabetes. 2006 Mar;55(3):849-55. doi: 10.2337/diabetes.55.03.06.db05-1418.
1299 A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.Diabetes. 2018 Jul;67(7):1414-1427. doi: 10.2337/db17-0914. Epub 2018 Apr 27.
1300 The E3 ubiquitin ligase parkin is dispensable for metabolic homeostasis in murine pancreatic cells and adipocytes.J Biol Chem. 2019 May 3;294(18):7296-7307. doi: 10.1074/jbc.RA118.006763. Epub 2019 Mar 15.
1301 New roles for prokineticin 2 in feeding behavior, insulin resistance and type 2 diabetes: Studies in mice and humans.Mol Metab. 2019 Nov;29:182-196. doi: 10.1016/j.molmet.2019.08.016. Epub 2019 Aug 28.
1302 Genetic association analysis of polymorphisms in PSD3 gene with obesity, type 2 diabetes, and HDL cholesterol.Diabetes Res Clin Pract. 2017 Apr;126:105-114. doi: 10.1016/j.diabres.2017.02.006. Epub 2017 Feb 10.
1303 Co-shared genetics and possible risk gene pathway partially explain the comorbidity of schizophrenia, major depressive disorder, type 2 diabetes, and metabolic syndrome.Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):186-203. doi: 10.1002/ajmg.b.32712. Epub 2019 Feb 6.
1304 Antitumor effects of metformin via indirect inhibition of protein phosphatase 2A in patients with endometrial cancer.PLoS One. 2018 Feb 14;13(2):e0192759. doi: 10.1371/journal.pone.0192759. eCollection 2018.
1305 Design, synthesis, biological evaluation and molecular dynamics simulation studies of (R)-5-methylthiazolidin-4-One derivatives as megakaryocyte protein tyrosine phosphatase 2 (PTP-MEG2) inhibitors for the treatment of type 2 diabetes.J Biomol Struct Dyn. 2020 Jul;38(11):3156-3165. doi: 10.1080/07391102.2019.1654410. Epub 2019 Aug 22.
1306 Artefactual inflation of type 2 diabetes prevalence in WHO STEP surveys.Trop Med Int Health. 2019 Apr;24(4):477-483. doi: 10.1111/tmi.13213. Epub 2019 Feb 17.
1307 Measuring gene-gene interaction using Kullback-Leibler divergence.Ann Hum Genet. 2019 Nov;83(6):405-417. doi: 10.1111/ahg.12324. Epub 2019 Jun 17.
1308 Impact of obesity-induced type 2 diabetes on long-term outcomes following stroke.Clin Sci (Lond). 2019 Jul 22;133(14):1603-1607. doi: 10.1042/CS20190492. Print 2019 Jul 31.
1309 Type 2 diabetes-associated fatty acid binding protein 2 promoter haplotypes are differentially regulated by GATA factors.Hum Mutat. 2008 Jan;29(1):142-9. doi: 10.1002/humu.20618.
1310 Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects.Horm Metab Res. 1998 Nov;30(11):656-62. doi: 10.1055/s-2007-978953.
1311 Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.Diabetes. 2013 Mar;62(3):977-86. doi: 10.2337/db12-0406. Epub 2012 Dec 3.
1312 EMT reversal in human cancer cells after IR knockdown in hyperinsulinemic mice.Endocr Relat Cancer. 2016 Sep;23(9):747-58. doi: 10.1530/ERC-16-0142. Epub 2016 Jul 19.
1313 Sarcopenic obesity is associated with a faster decline in renal function in people with type 2 diabetes.Diabet Med. 2020 Jan;37(1):105-113. doi: 10.1111/dme.14153. Epub 2019 Oct 30.
1314 Structure and in vitro hypoglycemic activity of a homogenous polysaccharide purified from Sargassum pallidum.Food Funct. 2019 May 22;10(5):2828-2838. doi: 10.1039/c8fo02525h.
1315 Clinical outcomes with canagliflozin according to baseline body mass index: results from post hoc analyses of the CANVAS Program.Diabetes Obes Metab. 2020 Apr;22(4):530-539. doi: 10.1111/dom.13920. Epub 2020 Jan 3.
1316 A heterozygous protein-truncating RFX6 variant in a family with childhood-onset, pregnancy-associated and adult-onset diabetes.Diabet Med. 2020 Oct;37(10):1772-1776. doi: 10.1111/dme.13970. Epub 2019 Jun 5.
1317 Association between MIC-1 and Type 2 Diabetes: A Combined Analysis.Dis Markers. 2019 Nov 16;2019:7284691. doi: 10.1155/2019/7284691. eCollection 2019.
1318 Deciphering the scalene association among type-2 diabetes mellitus, prostate cancer, and chronic myeloid leukemia via enrichment analysis of disease-gene network.Cancer Med. 2019 May;8(5):2268-2277. doi: 10.1002/cam4.1845. Epub 2019 Apr 1.
1319 Lecithin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes.J Nanobiotechnology. 2019 Jan 29;17(1):19. doi: 10.1186/s12951-019-0452-8.
1320 Ras associated with diabetes may play a role in fracture nonunion development in rats.BMC Musculoskelet Disord. 2019 Dec 12;20(1):602. doi: 10.1186/s12891-019-2970-9.
1321 Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey.PLoS Genet. 2018 Apr 5;14(4):e1007275. doi: 10.1371/journal.pgen.1007275. eCollection 2018 Apr.
1322 Molecular and clinical characterization of an insertional polymorphism of the insulin-receptor gene.Diabetes. 1989 Jun;38(6):737-43. doi: 10.2337/diab.38.6.737.
1323 Plasma Secretagogin is Increased in Individuals with Glucose Dysregulation.Exp Clin Endocrinol Diabetes. 2021 Sep;129(9):661-665. doi: 10.1055/a-1001-2244. Epub 2019 Sep 23.
1324 Shortening and intracellular Ca2+ in ventricular myocytes and expression of genes encoding cardiac muscle proteins in early onset type 2 diabetic Goto-Kakizaki rats.Exp Physiol. 2012 Dec;97(12):1281-91. doi: 10.1113/expphysiol.2012.066639. Epub 2012 May 11.
1325 Three interacting genomic loci incorporating two novel mutations underlie the evolution of diet-induced diabetes.Mol Med. 2016 Oct;22:560-569. doi: 10.2119/molmed.2016.00114. Epub 2016 Jul 26.
1326 Correlation between SEPS1 gene polymorphism and type 2 diabetes mellitus: A preliminary study.J Clin Lab Anal. 2019 Oct;33(8):e22967. doi: 10.1002/jcla.22967. Epub 2019 Jul 2.
1327 Molecular aspects of pancreatic -cell dysfunction: Oxidative stress, microRNA, and long noncoding RNA.J Cell Physiol. 2019 Jun;234(6):8411-8425. doi: 10.1002/jcp.27755. Epub 2018 Nov 22.
1328 Gastric bypass versus sleeve gastrectomy in patients with type 2 diabetes (Oseberg): a single-centre, triple-blind, randomised controlled trial.Lancet Diabetes Endocrinol. 2019 Dec;7(12):912-924. doi: 10.1016/S2213-8587(19)30344-4. Epub 2019 Oct 31.
1329 Proteomic analysis of serum biomarkers for prediabetes using the Long-Evans Agouti rat, a spontaneous animal model of type 2 diabetes mellitus.J Diabetes Investig. 2017 Sep;8(5):661-671. doi: 10.1111/jdi.12638. Epub 2017 Mar 27.
1330 Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.Am J Hum Genet. 2019 Dec 5;105(6):1076-1090. doi: 10.1016/j.ajhg.2019.10.001. Epub 2019 Oct 31.
1331 Sex-specific alteration to 2-antiplasmin incorporation in patients with type 2 diabetes.Thromb Res. 2020 Jan;185:55-62. doi: 10.1016/j.thromres.2019.09.032. Epub 2019 Oct 21.
1332 A novel thiazolidinediones ATZD2 rescues memory deficits in a rat model of type 2 diabetes through antioxidant and antiinflammation.Oncotarget. 2017 Nov 18;8(64):107409-107422. doi: 10.18632/oncotarget.22467. eCollection 2017 Dec 8.
1333 Diabetes Impedes the Epigenetic Switch of Macrophages into Repair Mode.Immunity. 2019 Aug 20;51(2):199-201. doi: 10.1016/j.immuni.2019.07.009.
1334 Haplotypes in vitamin D receptor gene encode risk in diabetic nephropathy.Gene. 2019 Jan 30;683:149-152. doi: 10.1016/j.gene.2018.10.017. Epub 2018 Oct 11.
1335 Differential expressions of SIRT1, SIRT3, and SIRT4 in peripheral blood mononuclear cells from patients with type 2 diabetic retinopathy.Arch Physiol Biochem. 2020 Oct;126(4):363-368. doi: 10.1080/13813455.2018.1543328. Epub 2018 Dec 20.
1336 PPAR promotes diabetes-associated centrosome amplification via increasing the expression of SKA1 directly at the transcriptional level.J Cell Physiol. 2019 Nov;234(11):20694-20703. doi: 10.1002/jcp.28674. Epub 2019 Apr 15.
1337 Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data.Genome Med. 2019 Mar 26;11(1):19. doi: 10.1186/s13073-019-0628-8.
1338 SNAP23 regulates BAX-dependent adipocyte programmed cell death independently of canonical macroautophagy.J Clin Invest. 2018 Aug 31;128(9):3941-3956. doi: 10.1172/JCI99217. Epub 2018 Aug 13.
1339 11beta-Hydroxysteroid dehydrogenase Type 1: genetic polymorphisms are associated with Type 2 diabetes in Pima Indians independently of obesity and expression in adipocyte and muscle.Diabetologia. 2004 Jun;47(6):1088-95. doi: 10.1007/s00125-004-1407-6. Epub 2004 May 20.
1340 Inhibition of JAK-STAT and NF-B signalling systems could be a novel therapeutic target against insulin resistance and type 2 diabetes.Life Sci. 2019 Dec 15;239:117045. doi: 10.1016/j.lfs.2019.117045. Epub 2019 Nov 12.
1341 SOCS2 exacerbates myocardial injury induced by ischemia/reperfusion in diabetic mice and H9c2 cells through inhibiting the JAK-STAT-IGF-1 pathway.Life Sci. 2017 Nov 1;188:101-109. doi: 10.1016/j.lfs.2017.08.036. Epub 2017 Sep 1.
1342 Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1.Acta Neuropathol Commun. 2016 Feb 25;4:16. doi: 10.1186/s40478-016-0282-y.
1343 SOX4 Allows Facultative -Cell Proliferation Through Repression of Cdkn1a.Diabetes. 2017 Aug;66(8):2213-2219. doi: 10.2337/db16-1074. Epub 2017 May 11.
1344 A novel role for the Krppel-like factor 14 on macrophage inflammatory response and atherosclerosis development.Cardiovasc Pathol. 2017 Mar-Apr;27:1-8. doi: 10.1016/j.carpath.2016.11.003. Epub 2016 Nov 14.
1345 The Effects of Soy Protein and Cocoa With or Without Isoflavones on Glycemic Control in Type 2 Diabetes. A Double-Blind, Randomized, Placebo-Controlled Study.Front Endocrinol (Lausanne). 2019 May 9;10:296. doi: 10.3389/fendo.2019.00296. eCollection 2019.
1346 The SPINK1 N34S mutation is not associated with Type 2 diabetes mellitus in a population of the USA.Diabet Med. 2005 Jun;22(6):744-8. doi: 10.1111/j.1464-5491.2005.01513.x.
1347 Intestinal peptide changes after bariatric and minimally invasive surgery: Relation to diabetes remission.Peptides. 2018 Feb;100:114-122. doi: 10.1016/j.peptides.2017.12.010.
1348 CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation.BMC Endocr Disord. 2019 Oct 29;19(1):115. doi: 10.1186/s12902-019-0442-8.
1349 Responsiveness of Patient-Reported Outcomes to Treatment Among Patients With Type 2 Diabetes Mellitus and OSA.Chest. 2020 Mar;157(3):665-672. doi: 10.1016/j.chest.2019.11.011. Epub 2019 Nov 27.
1350 Requirement for translocon-associated protein (TRAP) in insulin biogenesis.Sci Adv. 2019 Dec 4;5(12):eaax0292. doi: 10.1126/sciadv.aax0292. eCollection 2019 Dec.
1351 4-O-methylhonokiol ameliorates type 2 diabetes-induced nephropathy in mice likely by activation of AMPK-mediated fatty acid oxidation and Nrf2-mediated anti-oxidative stress.Toxicol Appl Pharmacol. 2019 May 1;370:93-105. doi: 10.1016/j.taap.2019.03.007. Epub 2019 Mar 12.
1352 Protocol: investigating the effectiveness and cost benefit of a lifestyle intervention targeting type 2 diabetes in Australia.BMC Endocr Disord. 2019 Jul 15;19(1):74. doi: 10.1186/s12902-019-0396-x.
1353 De-regulation of diabetic regulatory genes in psoriasis: Deciphering the unsolved riddle.Gene. 2016 Nov 15;593(1):110-116. doi: 10.1016/j.gene.2016.08.024. Epub 2016 Aug 13.
1354 Regulation of Artemisinin and Its Derivatives on the Assembly Behavior and Cytotoxicity of Amyloid Polypeptides hIAPP and A.ACS Chem Neurosci. 2019 Nov 20;10(11):4522-4534. doi: 10.1021/acschemneuro.9b00385. Epub 2019 Oct 16.
1355 Association of serum FAM19A5 with metabolic and vascular risk factors in human subjects with or without type 2 diabetes.Diab Vasc Dis Res. 2019 Nov;16(6):530-538. doi: 10.1177/1479164119860746. Epub 2019 Jul 8.
1356 Regular insulin added to total parenteral nutrition vs subcutaneous glargine in non-critically ill diabetic inpatients, a multicenter randomized clinical trial: INSUPAR trial.Clin Nutr. 2020 Feb;39(2):388-394. doi: 10.1016/j.clnu.2019.02.036. Epub 2019 Mar 20.
1357 RabGAPs in skeletal muscle function and exercise.J Mol Endocrinol. 2020 Jan;64(1):R1-R19. doi: 10.1530/JME-19-0143.
1358 TCF1 links GIPR signaling to the control of beta cell function and survival.Nat Med. 2016 Jan;22(1):84-90. doi: 10.1038/nm.3997. Epub 2015 Dec 7.
1359 Genetic variants within telomere-associated genes, leukocyte telomere length and the risk of acute coronary syndrome in Czech women.Clin Chim Acta. 2016 Feb 15;454:62-5. doi: 10.1016/j.cca.2015.12.041. Epub 2016 Jan 4.
1360 Training-induced alterations of skeletal muscle mitochondrial biogenesis proteins in non-insulin-dependent type 2 diabetic men.Can J Physiol Pharmacol. 2012 Dec;90(12):1634-41. doi: 10.1139/y2012-144. Epub 2012 Nov 29.
1361 Transcribing -cell mitochondria in health and disease.Mol Metab. 2017 May 31;6(9):1040-1051. doi: 10.1016/j.molmet.2017.05.014. eCollection 2017 Sep.
1362 Associations of Four Community Factors With Longitudinal Change in Hemoglobin A(1c) Levels in Patients With Type 2 Diabetes.Diabetes Care. 2018 Mar;41(3):461-468. doi: 10.2337/dc17-1200. Epub 2017 Dec 19.
1363 Increased Expression of the Innate Immune Receptor TLR10 in Obesity and Type-2 Diabetes: Association with ROS-Mediated Oxidative Stress.Cell Physiol Biochem. 2018;45(2):572-590. doi: 10.1159/000487034. Epub 2018 Jan 30.
1364 T-cadherin gene variants are associated with type 2 diabetes and the Fatty Liver Index in the French population.Diabetes Metab. 2017 Feb;43(1):33-39. doi: 10.1016/j.diabet.2016.05.005. Epub 2016 Jun 8.
1365 DEVOTE 5: Evaluating the Short-Term Cost-Utility of Insulin Degludec Versus Insulin Glargine U100 in Basal-Bolus Regimens for Type 2 Diabetes in the UK.Diabetes Ther. 2018 Jun;9(3):1217-1232. doi: 10.1007/s13300-018-0430-4. Epub 2018 Apr 30.
1366 Replication Study in a Japanese Population of Six Susceptibility Loci for Type 2 Diabetes Originally Identified by a Transethnic Meta-Analysis of Genome-Wide Association Studies.PLoS One. 2016 Apr 26;11(4):e0154093. doi: 10.1371/journal.pone.0154093. eCollection 2016.
1367 Role of Tmem163 in zinc-regulated insulin storage of MIN6 cells: Functional exploration of an Indian type 2 diabetes GWAS associated gene.Biochem Biophys Res Commun. 2020 Feb 19;522(4):1022-1029. doi: 10.1016/j.bbrc.2019.11.117. Epub 2019 Dec 6.
1368 Effects of X-chromosome Tenomodulin Genetic Variants on Obesity in a Children's Cohort and Implications of the Gene in Adipocyte Metabolism.Sci Rep. 2019 Mar 8;9(1):3979. doi: 10.1038/s41598-019-40482-0.
1369 Inflammatory Adipokines Decrease Expression of Two High Molecular Weight Isoforms of Tropomyosin Similar to the Change in Type 2 Diabetic Patients.PLoS One. 2016 Sep 20;11(9):e0162908. doi: 10.1371/journal.pone.0162908. eCollection 2016.
1370 TERC promotes cellular inflammatory response independent of telomerase.Nucleic Acids Res. 2019 Sep 5;47(15):8084-8095. doi: 10.1093/nar/gkz584.
1371 A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers.Br J Dermatol. 2017 Dec;177(6):1664-1670. doi: 10.1111/bjd.15787. Epub 2017 Nov 27.
1372 Mammalian Pseudokinase TRIB3 in Normal Physiology and Disease: Charting the Progress in Old and New Avenues.Curr Protein Pept Sci. 2017;18(8):819-842. doi: 10.2174/1389203718666170406124547.
1373 The prevalence of type 2 diabetes and associated risk factors with generalized osteoarthritis: a retrospective study using ICD codes for clinical data repository system.Clin Rheumatol. 2019 Dec;38(12):3539-3547. doi: 10.1007/s10067-019-04712-0. Epub 2019 Aug 7.
1374 Glucose-Sensitive Myokine/Cardiokine MG53 Regulates Systemic Insulin Response and Metabolic Homeostasis.Circulation. 2019 Feb 12;139(7):901-914. doi: 10.1161/CIRCULATIONAHA.118.037216.
1375 tRNA methyltransferase homologue gene TRMT10A mutation in young adult-onset diabetes with intellectual disability, microcephaly and epilepsy.Diabet Med. 2016 Sep;33(9):e21-5. doi: 10.1111/dme.13024.
1376 TGF-beta1 and TSC-22 gene polymorphisms and susceptibility to microvascular complications in type 2 diabetes.Nephron Physiol. 2007;106(4):p69-75. doi: 10.1159/000104874. Epub 2007 Jul 2.
1377 Deregulation of long noncoding RNA SNHG17 and TTC28-AS1 is associated with type 2 diabetes mellitus.Scand J Clin Lab Invest. 2019 Nov;79(7):519-523. doi: 10.1080/00365513.2019.1664760. Epub 2019 Sep 11.
1378 LMW-PTP modulates glucose metabolism in cancer cells.Biochim Biophys Acta Gen Subj. 2018 Dec;1862(12):2533-2544. doi: 10.1016/j.bbagen.2018.08.003. Epub 2018 Aug 4.
1379 The adhesion receptor GPR56 is activated by extracellular matrix collagen III to improve -cell function.Cell Mol Life Sci. 2018 Nov;75(21):4007-4019. doi: 10.1007/s00018-018-2846-4. Epub 2018 May 31.
1380 ALPK1 regulates streptozotocin-induced nephropathy through CCL2 and CCL5 expressions.J Cell Mol Med. 2019 Nov;23(11):7699-7708. doi: 10.1111/jcmm.14643. Epub 2019 Sep 26.
1381 SELF BLOOD GLUCOSE MONITORING UNDERESTIMATES HYPERGLYCEMIA AND HYPOGLYCEMIA AS COMPARED TO CONTINUOUS GLUCOSE MONITORING IN TYPE 1 AND TYPE 2 DIABETES.Endocr Pract. 2018 Jan;24(1):47-52. doi: 10.4158/EP-2017-0032. Epub 2017 Nov 16.
1382 Common variants in or near ZNRF1, COLEC12, SCYL1BP1 and API5 are associated with diabetic retinopathy in Chinese patients with type 2 diabetes.Diabetologia. 2015 Jun;58(6):1231-8. doi: 10.1007/s00125-015-3569-9. Epub 2015 Mar 28.
1383 Urinary AQP5 is independently associated with eGFR decline in patients with type 2 diabetes and nephropathy.Diabetes Res Clin Pract. 2019 Sep;155:107805. doi: 10.1016/j.diabres.2019.107805. Epub 2019 Aug 1.
1384 AQR is a novel type 2 diabetes-associated gene that regulates signaling pathways critical for glucose metabolism.J Genet Genomics. 2018 Feb 20;45(2):111-120. doi: 10.1016/j.jgg.2017.11.007. Epub 2018 Feb 14.
1385 Human Rho guanine nucleotide exchange factor 11 gene is associated with schizophrenia in a Japanese population.Hum Psychopharmacol. 2014 Nov;29(6):552-8. doi: 10.1002/hup.2435. Epub 2014 Oct 15.
1386 Early growth response protein-1 upregulates long noncoding RNA Arid2-IR to promote extracellular matrix production in diabetic kidney disease.Am J Physiol Cell Physiol. 2019 Mar 1;316(3):C340-C352. doi: 10.1152/ajpcell.00167.2018. Epub 2018 Nov 21.
1387 Impaired development and dysfunction of endothelial progenitor cells in type 2 diabetic mice.Diabetes Metab. 2017 Apr;43(2):154-162. doi: 10.1016/j.diabet.2016.07.034. Epub 2016 Sep 13.
1388 Isolated high home systolic blood pressure in patients with type 2 diabetes is a prognostic factor for the development of diabetic nephropathy: KAMOGAWA-HBP study.Diabetes Res Clin Pract. 2019 Dec;158:107920. doi: 10.1016/j.diabres.2019.107920. Epub 2019 Nov 8.
1389 Replication of recently described type 2 diabetes gene variants in a South Indian population.Metabolism. 2010 Dec;59(12):1760-6. doi: 10.1016/j.metabol.2010.04.024. Epub 2010 Jul 2.
1390 Exploring single nucleotide polymorphisms previously related to obesity and metabolic traits in pediatric-onset type 2 diabetes.Acta Diabetol. 2017 Jul;54(7):653-662. doi: 10.1007/s00592-017-0987-9. Epub 2017 Apr 12.
1391 Salivary chromogranin A and myeloid-related protein-8/14 from periodontitis patients with type 2 diabetes.Quintessence Int. 2019;50(10):808-814. doi: 10.3290/j.qi.a43233.
1392 Real-life achievement of lipid-lowering treatment targets in the DIAbetes and LifEstyle Cohort Twente: systemic assessment of pharmacological and nutritional factors.Nutr Diabetes. 2018 Apr 25;8(1):24. doi: 10.1038/s41387-018-0028-y.
1393 A Cross-Sectional Study Comparing the Prevalence of Bullous Pemphigoid Autoantibodies in 275 Cases of Type II Diabetes Mellitus Treated With or Without Dipeptidyl Peptidase-IV Inhibitors.Front Immunol. 2019 Jun 26;10:1439. doi: 10.3389/fimmu.2019.01439. eCollection 2019.
1394 Causal Impact of Type 2 Diabetes Mellitus on Cerebral Small Vessel Disease: A Mendelian Randomization Analysis.Stroke. 2018 Jun;49(6):1325-1331. doi: 10.1161/STROKEAHA.117.020536. Epub 2018 Apr 23.
1395 Cartilage Oligomeric Matrix Protein Levels in Type 2 Diabetes Associated with Primary Knee Osteoarthritis Patients.Genet Test Mol Biomarkers. 2019 Jan;23(1):16-22. doi: 10.1089/gtmb.2018.0184. Epub 2018 Dec 8.
1396 Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes.Diabetes. 2018 Jul;67(7):1428-1440. doi: 10.2337/db17-1164. Epub 2018 Apr 12.
1397 Association of a polymorphism in the promoter of the cellular retinoic acid-binding protein II gene (CRABP2) with increased circulating low-density lipoprotein cholesterol.Clin Chem Lab Med. 2007;45(5):615-20. doi: 10.1515/CCLM.2007.131.
1398 Biomarkers as predictors of sudden cardiac death in coronary artery disease patients with preserved left ventricular function (ARTEMIS study).PLoS One. 2018 Sep 18;13(9):e0203363. doi: 10.1371/journal.pone.0203363. eCollection 2018.
1399 Differentially expressed haptoglobin as a potential biomarker for type 2 diabetic mellitus in Hispanic population.Biofactors. 2017 May 6;43(3):424-433. doi: 10.1002/biof.1352. Epub 2017 Feb 20.
1400 Association between area-level socioeconomic status, accessibility and diabetes-related hospitalisations: a cross-sectional analysis of data from Western Victoria, Australia.BMJ Open. 2019 May 22;9(5):e026880. doi: 10.1136/bmjopen-2018-026880.
1401 Evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrates EFNB3 as a hypertension risk gene.Sci Rep. 2017 Mar 8;7:44114. doi: 10.1038/srep44114.
1402 Egr2 enhances insulin resistance via JAK2/STAT3/SOCS-1 pathway in HepG2 cells treated with palmitate.Gen Comp Endocrinol. 2018 May 1;260:25-31. doi: 10.1016/j.ygcen.2017.08.023. Epub 2017 Aug 24.
1403 DEXAMETHASONE STRESS TEST: A PILOT CLINICAL STUDY FOR IDENTIFICATION OF INDIVIDUALS HIGHLY PRONE TO DEVELOP TYPE 2 DIABETES.Endocr Pract. 2018 Oct 2;24(10):894-899. doi: 10.4158/EP-2018-0188. Epub 2018 Aug 7.
1404 Genome-wide methylation analysis identifies ELOVL5 as an epigenetic biomarker for the risk of type 2 diabetes mellitus.Sci Rep. 2018 Oct 5;8(1):14862. doi: 10.1038/s41598-018-33238-9.
1405 Promising cardiovascular and blood pressure effects of the SGLT2 inhibitors: a new class of antidiabetic drugs.Drugs Today (Barc). 2017 Mar;53(3):191-202. doi: 10.1358/dot.2017.53.3.2555985.
1406 FAM3 gene family: A promising therapeutical target for NAFLD and type 2 diabetes.Metabolism. 2018 Apr;81:71-82. doi: 10.1016/j.metabol.2017.12.001. Epub 2017 Dec 6.
1407 Studies on the interaction between HSA and new halogenated metformin derivatives: influence of lipophilic groups in the binding ability.J Biomol Struct Dyn. 2020 Apr;38(7):2128-2140. doi: 10.1080/07391102.2019.1627247. Epub 2019 Jun 11.
1408 Relationship among urinary albumin excretion rate, lipoprotein lipase PvuII polymorphism and plasma fibrinogen in type 2 diabetic patients.Physiol Res. 2006;55(1):55-62. doi: 10.33549/physiolres.930704. Epub 2005 Apr 26.
1409 Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism.Sci Rep. 2018 Oct 29;8(1):15973. doi: 10.1038/s41598-018-34238-5.
1410 Are serum concentrations of vitamin B-12 causally related to cardiometabolic risk factors and disease? A Mendelian randomization study.Am J Clin Nutr. 2018 Aug 1;108(2):398-404. doi: 10.1093/ajcn/nqy101.
1411 Predictors and Clinical Outcomes of Treatment Intensification in Patients With Type 2 Diabetes Uncontrolled on Basal Insulin in a Real-World Setting.Endocr Pract. 2018 Sep;24(9):805-814. doi: 10.4158/EP-2017-0261. Epub 2018 Jul 5.
1412 Peripheral Insulin Extraction in Non-Diabetic Subjects and Type 2 Diabetes Mellitus Patients.Exp Clin Endocrinol Diabetes. 2020 Aug;128(8):520-527. doi: 10.1055/a-0808-4029. Epub 2018 Dec 17.
1413 Nanoparticle abraxane possesses impaired proliferation in A549 cells due to the underexpression of glucosamine 6-phosphate N-acetyltransferase 1 (GNPNAT1/GNA1).Int J Nanomedicine. 2017 Mar 1;12:1685-1697. doi: 10.2147/IJN.S129976. eCollection 2017.
1414 Comparison of Great Curvature Plication with Duodenal-Jejunal Bypass (GCP-DJB) and Sleeve Gastrectomy (SG) on Metabolic Indices and Gut Hormones in Type 2 Diabetes Mellitus Rats.Obes Surg. 2018 Dec;28(12):4014-4021. doi: 10.1007/s11695-018-3459-6.
1415 Decreased GPIHBP1 protein levels in visceral adipose tissue partly underlie the hypertriglyceridemic phenotype in insulin resistance.PLoS One. 2018 Nov 8;13(11):e0205858. doi: 10.1371/journal.pone.0205858. eCollection 2018.
1416 A type 2 diabetes disease module with a high collective influence for Cdk2 and PTPLAD1 is localized in endosomes.PLoS One. 2018 Oct 9;13(10):e0205180. doi: 10.1371/journal.pone.0205180. eCollection 2018.
1417 Ablation of hephaestin and ceruloplasmin results in iron accumulation in adipocytes and type 2 diabetes.FEBS Lett. 2018 Feb;592(3):394-401. doi: 10.1002/1873-3468.12978. Epub 2018 Jan 31.
1418 Human lymphocyte antigen DR7 protects against proliferative retinopathy with type II diabetes mellitus.Arch Med Res. 2002 Mar-Apr;33(2):123-7. doi: 10.1016/s0188-4409(01)00378-2.
1419 Healthy lifestyle and normal waist circumference are associated with a lower 5-year risk of type 2 diabetes in middle-aged and elderly individuals: Results from the healthy aging longitudinal study in Taiwan (HALST).Medicine (Baltimore). 2017 Feb;96(6):e6025. doi: 10.1097/MD.0000000000006025.
1420 Heterogeneous Nuclear Ribonucleoprotein F Stimulates Sirtuin-1 Gene Expression and Attenuates Nephropathy Progression in Diabetic Mice.Diabetes. 2017 Jul;66(7):1964-1978. doi: 10.2337/db16-1588. Epub 2017 Apr 19.
1421 Inhibin E (INHBE) is a possible insulin resistance-associated hepatokine identified by comprehensive gene expression analysis in human liver biopsy samples.PLoS One. 2018 Mar 29;13(3):e0194798. doi: 10.1371/journal.pone.0194798. eCollection 2018.
1422 Using different anthropometric indices to assess prediction ability of type 2 diabetes in elderly population: a 5year prospective study.BMC Geriatr. 2018 Sep 17;18(1):218. doi: 10.1186/s12877-018-0912-2.
1423 THE ASSOCIATIONS BETWEEN HYPOVITAMINOSIS D, HIGHER PTH LEVELS WITH BONE MINERAL DENSITIES, AND RISK OF THE 10-YEAR PROBABILITY OF MAJOR OSTEOPOROTIC FRACTURES IN CHINESE PATIENTS WITH T2DM.Endocr Pract. 2018 Apr;24(4):334-341. doi: 10.4158/EP-2017-0164.
1424 Kcne2 deletion impairs insulin secretion and causes type 2 diabetes mellitus.FASEB J. 2017 Jun;31(6):2674-2685. doi: 10.1096/fj.201601347. Epub 2017 Mar 9.
1425 Genetic Variation in Kruppel like Factor 15 Is Associated with Left Ventricular Hypertrophy in Patients with Type 2 Diabetes: Discovery and Replication Cohorts.EBioMedicine. 2017 Apr;18:171-178. doi: 10.1016/j.ebiom.2017.03.036. Epub 2017 Mar 30.
1426 Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population.Diabetologia. 2018 Sep;61(9):2005-2015. doi: 10.1007/s00125-018-4659-2. Epub 2018 Jun 20.
1427 miR-29 contributes to normal endothelial function and can restore it in cardiometabolic disorders.EMBO Mol Med. 2018 Mar;10(3):e8046. doi: 10.15252/emmm.201708046.
1428 Influence of type 2 diabetes on muscle deoxygenation during ramp incremental cycle exercise.Respir Physiol Neurobiol. 2019 Nov;269:103258. doi: 10.1016/j.resp.2019.103258. Epub 2019 Jul 23.
1429 As Time Goes by: Anxiety Negatively Affects the Perceived Quality of Life in Patients With Type 2 Diabetes of Long Duration.Front Psychol. 2019 Jul 31;10:1779. doi: 10.3389/fpsyg.2019.01779. eCollection 2019.
1430 Common and rare exonic MUC5B variants associated with type 2 diabetes in Han Chinese.PLoS One. 2017 Mar 27;12(3):e0173784. doi: 10.1371/journal.pone.0173784. eCollection 2017.
1431 Mild hyperbaric oxygen inhibits the growth-related decline in skeletal muscle oxidative capacity and prevents hyperglycemia in rats with type 2 diabetes mellitus.J Diabetes. 2018 Sep;10(9):753-763. doi: 10.1111/1753-0407.12666. Epub 2018 May 17.
1432 Sex Differences in Cardiac Mitochondria in the New Zealand Obese Mouse.Front Endocrinol (Lausanne). 2018 Dec 4;9:732. doi: 10.3389/fendo.2018.00732. eCollection 2018.
1433 Gene variants in the NF-KB pathway (NFKB1, NFKBIA, NFKBIZ) and their association with type 2 diabetes and impaired renal function.Hum Immunol. 2018 Jun;79(6):494-498. doi: 10.1016/j.humimm.2018.03.008. Epub 2018 Mar 27.
1434 Somatic cell plasticity and Niemann-pick type C2 protein: adipocyte differentiation and function.J Biol Chem. 2010 Sep 24;285(39):30347-54. doi: 10.1074/jbc.M110.135939. Epub 2010 Jul 22.
1435 Overexpression of nuclear transport factor 2 may protect against diabetic retinopathy.Mol Vis. 2009;15:861-9. Epub 2009 Apr 27.
1436 Alcohol Intake Interacts with CDKAL1, HHEX, and OAS3 Genetic Variants, Associated with the Risk of Type 2 Diabetes by Lowering Insulin Secretion in Korean Adults.Alcohol Clin Exp Res. 2018 Dec;42(12):2326-2336. doi: 10.1111/acer.13888. Epub 2018 Oct 3.
1437 Outer Retinal Structure and Function Deficits Contribute to Circadian Disruption in Patients With Type 2 Diabetes.Invest Ophthalmol Vis Sci. 2019 May 1;60(6):1870-1878. doi: 10.1167/iovs.18-26297.
1438 A Novel Regulator of Type II Diabetes: MicroRNA-143.Trends Endocrinol Metab. 2018 Jun;29(6):380-388. doi: 10.1016/j.tem.2018.03.019. Epub 2018 Apr 18.
1439 Pregnancy-associated plasma protein-A is a stronger predictor for adverse cardiovascular outcomes after acute coronary syndrome in type-2 diabetes mellitus.Cardiovasc Diabetol. 2017 Apr 5;16(1):45. doi: 10.1186/s12933-017-0526-6.
1440 Whole-genome expression analyses of type 2 diabetes in human skin reveal altered immune function and burden of infection.Oncotarget. 2017 May 23;8(21):34601-34609. doi: 10.18632/oncotarget.16118.
1441 Association of rs12255372 (TCF7L2) and D76N (PDX-1) Polymorphisms with Type 2 Diabetes in a Population Living in Northeast Iran.Arch Iran Med. 2015 Jun;18(6):376-8.
1442 Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits.Psychosom Med. 2018 Apr;80(3):242-251. doi: 10.1097/PSY.0000000000000555.
1443 Associations of polymorphisms in the candidate genes for Alzheimer's disease BIN1, CLU, CR1 and PICALM with gestational diabetes and impaired glucose tolerance.Mol Biol Rep. 2017 Apr;44(2):227-231. doi: 10.1007/s11033-017-4100-9. Epub 2017 Mar 18.
1444 Dissociation of intramyocellular lipid storage and insulin resistance in trained athletes and type 2 diabetes patients; involvement of perilipin 5?.J Physiol. 2018 Mar 1;596(5):857-868. doi: 10.1113/JP275182. Epub 2017 Nov 23.
1445 Generalization of Rare Variant Association Tests for Longitudinal Family Studies.Genet Epidemiol. 2016 Feb;40(2):101-12. doi: 10.1002/gepi.21951. Epub 2016 Jan 18.
1446 Diabetes and branched-chain amino acids: What is the link?.J Diabetes. 2018 May;10(5):350-352. doi: 10.1111/1753-0407.12645. Epub 2018 Feb 13.
1447 Interaction between prenatal pesticide exposure and a common polymorphism in the PON1 gene on DNA methylation in genes associated with cardio-metabolic disease risk-an exploratorystudy.Clin Epigenetics. 2017 Apr 5;9:35. doi: 10.1186/s13148-017-0336-4. eCollection 2017.
1448 Prolactin regulatory element-binding (PREB) protein regulates hepatic glucose homeostasis.Biochim Biophys Acta Mol Basis Dis. 2018 Jun;1864(6 Pt A):2097-2107. doi: 10.1016/j.bbadis.2018.03.024. Epub 2018 Mar 28.
1449 Preparation of a nanoscale dihydromyricetin-phospholipid complex to improve the bioavailability: in vitro and in vivo evaluations.Eur J Pharm Sci. 2019 Oct 1;138:104994. doi: 10.1016/j.ejps.2019.104994. Epub 2019 Jul 11.
1450 The association study of high-sensitivity C-reactive protein, pentraxin 3, nitrotyrosine, and insulin dose in patients with insulin-treated type 2 diabetes mellitus.Ther Clin Risk Manag. 2018 May 28;14:955-963. doi: 10.2147/TCRM.S162086. eCollection 2018.
1451 Identification of novel alleles associated with insulin resistance in childhood obesity using pooled-DNA genome-wide association study approach.Int J Obes (Lond). 2018 Apr;42(4):686-695. doi: 10.1038/ijo.2017.293. Epub 2017 Nov 30.
1452 Allosteric binding sites in Rab11 for potential drug candidates.PLoS One. 2018 Jun 6;13(6):e0198632. doi: 10.1371/journal.pone.0198632. eCollection 2018.
1453 The neuronal and endocrine roles of RCAN1 in health and disease.Clin Exp Pharmacol Physiol. 2018 Apr;45(4):377-383. doi: 10.1111/1440-1681.12884. Epub 2017 Nov 29.
1454 Reticulocalbin 2 enhances osteogenic differentiation of human vascular smooth muscle cells in diabetic conditions.Life Sci. 2019 Sep 15;233:116746. doi: 10.1016/j.lfs.2019.116746. Epub 2019 Aug 9.
1455 Correlation between reactive oxygen metabolites & atherosclerotic risk factors in patients with type 2 diabetes mellitus.Indian J Med Res. 2013 Apr;137(4):742-8.
1456 The rs6060566 of the reactive oxygen species modulator 1 (Romo-1) gene affects Romo-1 expression and the development of diabetic retinopathy in Caucasians with type 2 diabetes.Acta Ophthalmol. 2015 Dec;93(8):e654-7. doi: 10.1111/aos.12723. Epub 2015 Mar 30.
1457 Impact of treatment strategies on outcomes in patients with stable coronary artery disease and type 2 diabetes mellitus according to presenting angina severity: A pooled analysis of three federally-funded randomized trials.Atherosclerosis. 2018 Oct;277:186-194. doi: 10.1016/j.atherosclerosis.2018.04.005. Epub 2018 Jun 1.
1458 The Gly146Ala variation in human SF-1 gene: its association with insulin resistance and type 2 diabetes in Chinese.Diabetes Res Clin Pract. 2006 Sep;73(3):322-8. doi: 10.1016/j.diabres.2006.02.007. Epub 2006 Mar 27.
1459 Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes.Diabetologia. 2018 Feb;61(2):399-412. doi: 10.1007/s00125-017-4462-5. Epub 2017 Oct 7.
1460 COMPARING CLINICAL OUTCOMES AND COSTS FOR DIFFERENT TREATMENT INTENSIFICATION APPROACHES IN PATIENTS WITH TYPE 2 DIABETES UNCONTROLLED ON BASAL INSULIN: ADDING GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS VERSUS ADDING RAPID-ACTING INSULIN OR INCREASING BASAL INSULIN DOSE.Endocr Pract. 2017 Nov;23(11):1316-1324. doi: 10.4158/EP171769.OR. Epub 2017 Aug 17.
1461 Siglec-7 restores -cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes.Sci Rep. 2017 Apr 5;7:45319. doi: 10.1038/srep45319.
1462 CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type.Nucleic Acids Res. 2018 Nov 30;46(21):e124. doi: 10.1093/nar/gky698.
1463 Role of SLMAP genetic variants in susceptibility of diabetes and diabetic retinopathy in Qatari population.J Transl Med. 2015 Feb 15;13:61. doi: 10.1186/s12967-015-0411-6.
1464 Proteomic analysis reveals downregulation of housekeeping proteins in the diabetic vascular proteome.Acta Diabetol. 2017 Feb;54(2):171-190. doi: 10.1007/s00592-016-0929-y. Epub 2016 Oct 28.
1465 Type 2 Diabetes Leads to Axon Initial Segment Shortening in db/db Mice.Front Cell Neurosci. 2018 Jun 8;12:146. doi: 10.3389/fncel.2018.00146. eCollection 2018.
1466 Synthesis and characterization of some atypical sphingoid bases.Bioorg Med Chem. 2018 Aug 7;26(14):4047-4057. doi: 10.1016/j.bmc.2018.06.031. Epub 2018 Jun 23.
1467 Association of TATA box-binding protein-associated factor RNA polymerase I subunit C (TAF1C) with T2DM.Gene. 2019 Jul 20;706:43-51. doi: 10.1016/j.gene.2019.04.076. Epub 2019 Apr 27.
1468 A comparison of clinical efficacy and economic value in Basalin- and Lantus-treated patients with type 2 diabetes using continuous glucose monitoring system.J Endocrinol Invest. 2018 Feb;41(2):179-184. doi: 10.1007/s40618-017-0712-0. Epub 2017 Jun 22.
1469 Non-Alcoholic Fatty Liver Disease Treatment in Patients with Type 2 Diabetes Mellitus; New Kids on the Block.Curr Vasc Pharmacol. 2020;18(2):172-181. doi: 10.2174/1570161117666190405164313.
1470 Whole-exome sequencing in maya indigenous families: variant in PPP1R3A is associated with type 2 diabetes. Mol Genet Genomics. 2018 Oct;293(5):1205-1216. doi: 10.1007/s00438-018-1453-2. Epub 2018 Jun 11.
1471 Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases.PLoS One. 2016 Aug 10;11(8):e0160573. doi: 10.1371/journal.pone.0160573. eCollection 2016.