General Information of Disease (ID: DIS59VMN)

Disease Name Psoriasis
Disease Class EA90: Psoriasis
Definition
An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.
Disease Hierarchy
DISAEGPH: Immune system disorder
DISY5SZC: Dermatitis
DISSCALK: Hereditary skin disorder
DIS59VMN: Psoriasis
ICD Code
ICD-11
ICD-11: EA90
Disease Identifiers
MONDO ID
MONDO_0005083
MESH ID
D011565
UMLS CUI
C0033860
MedGen ID
10997
SNOMED CT ID
9014002

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 16 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Atorvastatin DMF28YC Approved Small molecular drug [1]
Betamethasone DMAHJEF Approved Small molecular drug [2]
Calcipotriol DM03CP7 Approved Small molecular drug [3]
Cortisone Acetate DMG8K57 Approved Small molecular drug [4]
Dexamethasone DMMWZET Approved Small molecular drug [5]
Erlotinib DMCMBHA Approved Small molecular drug [6]
Hydrocortisone DMGEMB7 Approved Small molecular drug [7]
Methotrexate DM2TEOL Approved Small molecular drug [8]
Methylprednisolone DM4BDON Approved Small molecular drug [9]
Nicotinamide DMUPE07 Approved Small molecular drug [10]
Prednisolone DMQ8FR2 Approved Small molecular drug [11]
Prednisone DM2HG4X Approved Small molecular drug [12]
Tazarotene DM8SMD1 Approved Small molecular drug [13]
Triamcinolone DM98IXF Approved Small molecular drug [14]
Ustekinumab DMHTYK3 Approved Antibody [15]
Vitamin B3 DMQVRZH Approved Small molecular drug [16]
------------------------------------------------------------------------------------
⏷ Show the Full List of 16 Drug(s)
This Disease is Treated as An Indication in 4 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Benzylpenicillin DMS9503 Phase 3 Small molecular drug [17]
JNJ-77242113 DM6DLXK Phase 2 NA [19]
PF-07038124 DMI4RUI Phase 2 Small molecule [20]
JNJ-1459 DMEK1OJ Phase 1 NA [21]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 1 Drugs in Phase 2 Trial
Drug Name Drug ID Highest Status Drug Type REF
Cyclosporin A DMUYKBZ Phase 2 Trial Small molecular drug [18]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 1 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
DYV024 DM0TSOZ Preclinical NA [22]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 250 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ALDH2 TTFLN4T Limited Genetic Variation [23]
ANTXR2 TTOD34I Limited Genetic Variation [24]
ATXN2 TTPQJ7P Limited Genetic Variation [24]
CASR TTBUYHA Limited Genetic Variation [23]
CLCN6 TTCJRDO Limited Genetic Variation [23]
CS TTZA6B3 Limited Genetic Variation [25]
DNMT3A TTJUALD Limited Genetic Variation [24]
ERN1 TTKIAT3 Limited Genetic Variation [24]
ETS1 TTTGPSD Limited Genetic Variation [24]
F9 TTFEZ5Q Limited Biomarker [26]
GART TTEXB9Z Limited Genetic Variation [23]
GJB2 TTRGZX3 Limited Genetic Variation [27]
GPR183 TTME5YJ Limited Genetic Variation [28]
GPR35 TT254XD Limited Genetic Variation [24]
HDAC7 TTMUEK1 Limited Genetic Variation [24]
HLA-A TTHONFT Limited Genetic Variation [29]
HLA-DQA1 TTU2I3J Limited Genetic Variation [30]
IFNGR2 TT13TL0 Limited Genetic Variation [24]
IL15 TTJFA35 Limited Biomarker [31]
IL19 TT87RWS Limited Altered Expression [32]
IL20 TTNZMY2 Limited Biomarker [33]
IL21 TT9QEJ6 Limited Altered Expression [34]
KEAP1 TT3Z6Y9 Limited Genetic Variation [24]
KLRC1 TTC4IMS Limited Genetic Variation [28]
KSR1 TTHL1TV Limited Genetic Variation [24]
LRRK2 TTK0FEA Limited Genetic Variation [24]
MGMT TTJ8DV7 Limited Genetic Variation [25]
NOS2 TTF10I9 Limited Genetic Variation [24]
NPEPPS TT371QC Limited Genetic Variation [24]
NR5A2 TTAU3SY Limited Genetic Variation [24]
OSMR TTAH0KM Limited Genetic Variation [24]
PDE4A TTZ97H5 Limited Biomarker [35]
PPARG TTT2SVW Limited Genetic Variation [36]
PRKCB TTYPXQF Limited Genetic Variation [24]
PRKCQ TT1MS7X Limited Genetic Variation [24]
RGS6 TTJ96M8 Limited Genetic Variation [37]
RIC8B TT26BHC Limited Genetic Variation [24]
RPS6KB1 TTG0U4H Limited Genetic Variation [24]
SH2B3 TT36N7Z Limited Genetic Variation [24]
TLR7 TTRJ1K4 Limited Posttranslational Modification [38]
TNFRSF14 TTWGTC1 Limited Genetic Variation [24]
DAG1 TT4X7PG moderate Genetic Variation [39]
DDX58 TTVB0O3 moderate Biomarker [40]
ITGB2 TTIJWR7 moderate Genetic Variation [41]
ACE2 TTUI5H7 Strong Genetic Variation [42]
ACKR1 TTKY2NS Strong Altered Expression [43]
ADAM33 TTQICM2 Strong Biomarker [44]
ADRA1B TTBRKXS Strong Genetic Variation [45]
AHCY TTE2KUJ Strong Biomarker [46]
AHR TT037IE Strong Genetic Variation [47]
AKR1C3 TT5ZWB6 Strong Biomarker [48]
AKT3 TTO6SGY Strong Biomarker [49]
ALOX12 TT12ABZ Strong Genetic Variation [50]
AMOT TTI48OS Strong Altered Expression [51]
AOC1 TTM3B5R Strong Genetic Variation [52]
AOC3 TT7HC21 Strong Genetic Variation [53]
APOB TTN1IE2 Strong Biomarker [54]
APOE TTKS9CB Strong Genetic Variation [55]
AREG TT76B3W Strong Biomarker [56]
BMP6 TT07RIB Strong Altered Expression [57]
BMX TTN2I9E Strong Biomarker [58]
BST2 TT90BJT Strong Biomarker [59]
C5AR1 TTHXFA1 Strong Biomarker [60]
CA2 TTANPDJ Strong Genetic Variation [61]
CALCA TTVSFJW Strong Biomarker [62]
CAPN1 TT1WBIJ Strong Biomarker [63]
CARM1 TTIZQFJ Strong Biomarker [64]
CASP5 TTWR48J Strong Altered Expression [65]
CAT TTPS279 Strong Altered Expression [66]
CCKAR TTCG0AL Strong Genetic Variation [67]
CCKBR TTVFO0U Strong Genetic Variation [67]
CCL17 TTMPHAE Strong Altered Expression [68]
CCL20 TT2XAZY Strong Biomarker [69]
CCR1 TTC24WT Strong Altered Expression [70]
CCR4 TT7HQD0 Strong Biomarker [71]
CCR6 TTFDB30 Strong Biomarker [69]
CD1A TTBGTFN Strong Biomarker [72]
CD200 TT0BE68 Strong Biomarker [73]
CD27 TTDO1MV Strong Biomarker [74]
CD40 TT1ERKL Strong Genetic Variation [24]
CD6 TTMF6KC Strong Biomarker [75]
CD69 TTPQE9F Strong Biomarker [76]
CDK5R1 TTBYM6V Strong Biomarker [77]
CFB TTA0P7K Strong Genetic Variation [78]
CMKLR1 TT4UGZL Strong Biomarker [79]
COPS5 TTSTNJR Strong Altered Expression [80]
CRHR1 TT7EFHR Strong Altered Expression [81]
CRHR2 TTIY658 Strong Biomarker [82]
CSF2 TTNYZG2 Strong Biomarker [83]
CTSG TTQAJF1 Strong Biomarker [84]
CTSS TTUMQVO Strong Biomarker [85]
CTSV TTSD9T1 Strong Altered Expression [86]
CX3CL1 TT1OFBQ Strong Biomarker [87]
CXCL10 TTQOVYA Strong Biomarker [88]
CXCL11 TTWG0RE Strong Altered Expression [89]
CXCL9 TTWE5PB Strong Altered Expression [90]
CXCR1 TTMWT8Z Strong Altered Expression [70]
CXCR2 TT30C9G Strong Altered Expression [91]
CYP24A1 TT82UI1 Strong Altered Expression [92]
DEFB4A TTIVY12 Strong Genetic Variation [93]
DUSP1 TTG8HIM Strong Biomarker [94]
DUT TTH6MBO Strong Biomarker [95]
EGF TTED8JB Strong Altered Expression [96]
EIF2AK1 TTRUJBV Strong Genetic Variation [97]
ERAP2 TTVGS1C Strong Genetic Variation [98]
F13A1 TTXI2RA Strong Biomarker [99]
FABP1 TTIV96N Strong Biomarker [100]
FABP4 TTHWMFZ Strong Biomarker [101]
FCGR2A TTXT21W Strong Genetic Variation [102]
FFAR2 TT0FYAN Strong Altered Expression [103]
FGF19 TTGCH11 Strong Altered Expression [104]
FLT4 TTDCBX5 Strong Altered Expression [105]
FOSL1 TTY8LZG Strong Genetic Variation [106]
FOSL2 TT689IR Strong Altered Expression [107]
FPR2 TTOJ1NF Strong Biomarker [108]
FURIN TTH9WF6 Strong Biomarker [109]
GEM TTAZF9M Strong Biomarker [110]
GGH TTZJRL0 Strong Genetic Variation [111]
GRHL2 TTUGH4C Strong Altered Expression [112]
GRIN1 TTLD29N Strong Altered Expression [113]
HAX1 TT21BYA Strong Altered Expression [114]
HBEGF TT15SL0 Strong Altered Expression [115]
HCAR2 TTWNV8U Strong Altered Expression [103]
HNRNPA1 TTPJ9XK Strong Biomarker [116]
HOXA5 TTXSVQP Strong Biomarker [117]
HRH4 TTXJ178 Strong Genetic Variation [118]
HTR1A TTSQIFT Strong Biomarker [119]
HTR2A TTJQOD7 Strong Genetic Variation [120]
IFNAR1 TTSYFMA Strong Altered Expression [121]
IKZF3 TTCZVFZ Strong Genetic Variation [122]
IL12RB2 TT4SWR8 Strong Genetic Variation [123]
IL13RA1 TTNEAMG Strong Altered Expression [124]
IL13RA2 TTMPZ7V Strong Altered Expression [125]
IL15RA TTGN89I Strong Altered Expression [126]
IL17D TTC5LTG Strong Biomarker [127]
IL1R1 TTWOTEA Strong Genetic Variation [24]
IL1RAP TTWS50K Strong Biomarker [128]
IL1RL2 TTUS18T Strong Biomarker [129]
IL21R TTZO9B0 Strong Altered Expression [130]
IL24 TT1EPXZ Strong Genetic Variation [131]
IL25 TTVMO5W Strong Biomarker [132]
IL2RA TT10Y9E Strong Genetic Variation [24]
IL31 TT1RJXK Strong Biomarker [133]
IL32 TTD4G7L Strong Altered Expression [134]
IL36G TT8SLDN Strong Altered Expression [135]
IL4 TTLGTKB Strong Biomarker [136]
IL4R TTDWHC3 Strong Altered Expression [124]
IL7 TT8FRMO Strong Biomarker [137]
IL9 TT0JTFD Strong Biomarker [138]
ITGAE TTH0Z37 Strong Biomarker [76]
ITGAL TT48WR6 Strong Genetic Variation [24]
JAK1 TT6DM01 Strong Biomarker [139]
KLK5 TTULSEW Strong Biomarker [140]
KLK6 TTLPF4X Strong Biomarker [141]
KLK7 TTE6GTB Strong Altered Expression [142]
KLK8 TTH5MRS Strong Biomarker [141]
LAMP1 TTC214J Strong Biomarker [143]
LANCL1 TTZW8NS Strong Biomarker [138]
LTA TTP73TM Strong Genetic Variation [144]
LYN TT1RWNJ Strong Altered Expression [145]
LYVE1 TTG8DNU Strong Biomarker [146]
MALT1 TTCI81G Strong Biomarker [147]
MAPKAPK2 TTMUG9D Strong Altered Expression [148]
MBTPS1 TTNSM2I Strong Biomarker [149]
MC1R TT0MV2T Strong Genetic Variation [150]
MCHR1 TTX4RTB Strong Biomarker [151]
MKI67 TTB4UNG Strong Biomarker [152]
MMP10 TTXLEG7 Strong Biomarker [153]
NAGLU TTDM6HZ Strong Genetic Variation [154]
NEDD8 TTNDC4K Strong Altered Expression [155]
NFKBIA TTSHAEB Strong Genetic Variation [156]
NOTCH4 TTXDIK2 Strong Biomarker [157]
NPSR1 TTV1C0Z Strong Genetic Variation [158]
NR1H3 TTECBXN Strong Biomarker [159]
NTSR1 TTTUMEP Strong Biomarker [160]
OLR1 TTKSND3 Strong Altered Expression [161]
OPRK1 TTQW87Y Strong Altered Expression [162]
OPRM1 TTKWM86 Strong Genetic Variation [163]
PCNA TTLG1PD Strong Biomarker [164]
PDE3A TT06AWU Strong Biomarker [165]
PDE4B TTVIAT9 Strong Altered Expression [166]
PDE7A TT1BC3A Strong Biomarker [167]
PECAM1 TT4EZB2 Strong Biomarker [168]
PLA2G7 TTDNFMT Strong Biomarker [169]
POLR2G TTD4YFP Strong Altered Expression [170]
PRKCZ TTBSN0L Strong Altered Expression [171]
PSMB8 TTEAD9J Strong Biomarker [172]
PSMB9 TTOUSTQ Strong Biomarker [172]
PTPN2 TTY8PUS Strong Genetic Variation [173]
QPCT TTJ7YTV Strong Biomarker [174]
REG3A TTL4H8N Strong Altered Expression [175]
REN TTB2MXP Strong Biomarker [176]
RIPK1 TTVJHX8 Strong Biomarker [177]
RNF7 TTODWGT Strong Genetic Variation [178]
RPS6KA5 TTYXEPL Strong Biomarker [179]
RPSA TTLUW5B Strong Biomarker [138]
RUNX3 TTKCVO7 Strong Biomarker [180]
RYR1 TTU5CIX Strong Genetic Variation [181]
S100A9 TT0TMQG Strong Biomarker [182]
S100B TTQ0V86 Strong Altered Expression [183]
S1PR1 TT9JZCK Strong Biomarker [184]
SAA1 TTY0DN9 Strong Altered Expression [185]
SCARB1 TTRE324 Strong Biomarker [186]
SELP TTE5VG0 Strong Biomarker [187]
SELPLG TTS5K8U Strong Altered Expression [188]
SEMA3A TTVKD3S Strong Biomarker [189]
SEMA4D TT5UT28 Strong Biomarker [190]
SLC22A1 TTM5Q4V Strong Genetic Variation [191]
SLCO1B1 TTFGXEB Strong Genetic Variation [191]
SLCO1C1 TT340CE Strong Biomarker [165]
SMAD3 TTHQZV7 Strong Genetic Variation [24]
SPHK2 TTCN0M9 Strong Biomarker [192]
STAB1 TTJFEOC Strong Biomarker [193]
SULF2 TTLQTHB Strong Biomarker [194]
TBK1 TTMP03S Strong Biomarker [195]
TEK TT9VGXW Strong Altered Expression [196]
TFPI TT068JH Strong Biomarker [197]
TGFA TTTLQFR Strong Biomarker [198]
TGM1 TT7A949 Strong Altered Expression [199]
TLR2 TTY7ZHS Strong Genetic Variation [200]
TLR4 TTISGCA Strong Altered Expression [201]
TLR6 TTWRI8V Strong Altered Expression [202]
TLR8 TT8CWFK Strong Altered Expression [203]
TLR9 TTSHG0T Strong Genetic Variation [204]
TNFRSF13B TTL9OD4 Strong Altered Expression [205]
TNFRSF13C TT7NJSE Strong Biomarker [206]
TNFRSF17 TTZ3P4W Strong Biomarker [206]
TNFRSF1A TTG043C Strong Genetic Variation [24]
TNFRSF4 TTL31H0 Strong Altered Expression [107]
TNFSF12 TTBTDM1 Strong Biomarker [207]
TNFSF15 TTEST6I Strong Genetic Variation [208]
TRIM27 TTTO3QN Strong Altered Expression [209]
TRPV1 TTMI6F5 Strong Biomarker [210]
TSLP TTHMW3T Strong Altered Expression [211]
TXK TT8M1DP Strong Biomarker [212]
TYK2 TTBYWP2 Strong Biomarker [213]
USP2 TTUEQ1W Strong Biomarker [214]
ACR TTAHE2N Definitive Biomarker [215]
ADAM17 TT6AZXG Definitive Biomarker [216]
CCL22 TTBTWI1 Definitive Biomarker [217]
CXCL1 TTLK1RW Definitive Biomarker [218]
FCGR3A TTIFOC0 Definitive Genetic Variation [219]
FGF7 TTFY134 Definitive Biomarker [220]
JUN TTS7IR5 Definitive Altered Expression [221]
KYNU TTWQM3J Definitive Biomarker [222]
PPARD TT2JWF6 Definitive Biomarker [223]
SELE TT1PL7M Definitive Biomarker [224]
SERPINB3 TT6QLPX Definitive Altered Expression [225]
TNFRSF1B TT63WSF Definitive Genetic Variation [226]
WNT5A TTKG7F8 Definitive Altered Expression [227]
------------------------------------------------------------------------------------
⏷ Show the Full List of 250 DTT(s)
This Disease Is Related to 10 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
KCNH7 DT3WXPI Limited Genetic Variation [25]
SLC39A11 DTEOAND Limited Genetic Variation [24]
SLC9A8 DTNY0C2 Limited Genetic Variation [24]
SLC12A8 DT0OA2B Strong Genetic Variation [228]
SLC25A20 DTQOUM4 Strong Genetic Variation [61]
SLC25A5 DTL1TRY Strong Altered Expression [229]
SLC52A1 DT7NOKR Strong Biomarker [230]
SLC7A9 DTP7AEQ Strong Biomarker [157]
SLC9C2 DT2N5HO Strong Biomarker [231]
SLCO6A1 DTIFXNS Strong Genetic Variation [232]
------------------------------------------------------------------------------------
⏷ Show the Full List of 10 DTP(s)
This Disease Is Related to 13 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
PARK7 DEPOVCH Limited Genetic Variation [24]
ACOT13 DEMK5U6 Strong Biomarker [233]
AKR1B10 DEP6GT1 Strong Biomarker [234]
AKR1C1 DE7P2FB Strong Biomarker [48]
CYP27A1 DEBS639 Strong Altered Expression [235]
CYP27B1 DE3FYEM Strong Biomarker [235]
CYP2S1 DE6NMGO Strong Biomarker [236]
IPMK DESA9EX Strong Genetic Variation [237]
MSMO1 DE5FUD0 Strong Biomarker [238]
NAT1 DE7OAB3 Strong Genetic Variation [239]
SCLY DEH4TD6 Strong Genetic Variation [240]
TGM3 DEOEB3Q Strong Biomarker [241]
TGM5 DEW8QEH Strong Biomarker [242]
------------------------------------------------------------------------------------
⏷ Show the Full List of 13 DME(s)
This Disease Is Related to 407 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ACO1 OT2VUR7L Limited Genetic Variation [25]
ACTA2 OTEDLG8E Limited Genetic Variation [24]
ADCY3 OTGOQM6B Limited Genetic Variation [24]
AP5B1 OTZGM9QA Limited Genetic Variation [23]
ASAP2 OTGEXULW Limited Genetic Variation [24]
ATG16L1 OTEOYC5D Limited Genetic Variation [24]
ATG5 OT4T5SMS Limited Genetic Variation [24]
BACH2 OT17GS18 Limited Genetic Variation [24]
BLOC1S2 OTUR3E76 Limited Genetic Variation [28]
BPTF OTD1RZAD Limited Genetic Variation [23]
BSN OTZ72VIB Limited Genetic Variation [24]
C17orf67 OTCL5EE8 Limited Genetic Variation [24]
C1orf141 OTASPHL0 Limited Genetic Variation [24]
CAMK2G OTHD9KJG Limited Genetic Variation [243]
CARD9 OTJ81AWD Limited Genetic Variation [24]
CAST OTBXZZGF Limited Genetic Variation [25]
CAVIN1 OTFO915U Limited Genetic Variation [244]
CCHCR1 OT22C116 Limited Genetic Variation [245]
CDKN2D OT2TTZPZ Limited Biomarker [26]
CFL1 OTT6D5MH Limited Genetic Variation [28]
CHST8 OTQT4TKR Limited Genetic Variation [25]
CLEC16A OTLGV5SV Limited Genetic Variation [24]
CMC1 OTCWYKPI Limited Genetic Variation [24]
CPEB4 OTW1SCZW Limited Genetic Variation [24]
CREM OTJIJ5AL Limited Genetic Variation [24]
DAP OT5YLL7E Limited Genetic Variation [24]
DENND1B OT3VCNPE Limited Genetic Variation [24]
DNAJB4 OTUD01BK Limited Genetic Variation [28]
DONSON OTN5HE0W Limited Genetic Variation [23]
ELMO1 OTY2ORXK Limited Genetic Variation [25]
ELOA OTOQTF5K Limited Genetic Variation [25]
EXOC2 OT5QG1WG Limited Genetic Variation [25]
FAM118A OT6EM97E Limited Genetic Variation [24]
FAM177A1 OTXTA14N Limited Genetic Variation [24]
FIBP OTI7131S Limited Genetic Variation [24]
GAL3ST2 OTZT1PLE Limited Genetic Variation [24]
GCKR OTSIWXGG Limited Genetic Variation [24]
GIPC2 OT68YFO1 Limited Genetic Variation [28]
GLYAT OT3WWYXD Limited Genetic Variation [24]
GNA12 OT3IRZH3 Limited Genetic Variation [24]
GPR160 OTMXJT73 Limited Genetic Variation [23]
HIPK1 OTSEA8RS Limited Genetic Variation [24]
ICAM5 OTDGGAFH Limited Genetic Variation [25]
IFIH1 OTZA2AHA Limited Biomarker [246]
IKBKE OT5VYOSM Limited Genetic Variation [28]
IL17B OTS86H50 Limited Biomarker [33]
IL17RA OTVVI8ER Limited Genetic Variation [247]
IL18R1 OT83XMPQ Limited Genetic Variation [24]
IL6R OTCQL07Z Limited Genetic Variation [24]
INAVA OTGXNB86 Limited Genetic Variation [24]
IRGM OTKD3O5Z Limited Genetic Variation [24]
ITPRID1 OT9MH0BX Limited Genetic Variation [23]
KLF13 OTMIKHZ4 Limited Genetic Variation [28]
KPRP OTRJF3OY Limited Genetic Variation [23]
LRRC43 OTCINBGT Limited Genetic Variation [28]
MFSD4B OTHHKWRT Limited Genetic Variation [244]
MST1 OTOC4UNG Limited Genetic Variation [24]
MYPN OTHTOFDU Limited Genetic Variation [23]
MYRF OTKF6AEB Limited Genetic Variation [24]
MYT1L OTV45MAS Limited Genetic Variation [25]
NDFIP1 OTIORSWF Limited Genetic Variation [24]
NPPA OTMQNTNX Limited Genetic Variation [23]
PAK5 OT32WQGL Limited Genetic Variation [244]
PKIG OTOIWE5G Limited Genetic Variation [24]
PLCL2 OTK5FDF6 Limited Genetic Variation [243]
POLI OTBA4DCE Limited Genetic Variation [244]
PPP2R3C OT7E6V9B Limited Genetic Variation [24]
PRDM1 OTQLSVBS Limited Genetic Variation [24]
PRORP OTWIS44P Limited Genetic Variation [25]
PTPRN2 OTL6SH28 Limited Genetic Variation [25]
PUS10 OTFFJWZX Limited Genetic Variation [24]
QTRT1 OTC33MCV Limited Genetic Variation [25]
RAD50 OTYMU9G1 Limited Genetic Variation [25]
RASIP1 OTCRY2AN Limited Genetic Variation [25]
RAVER1 OTMHBTLE Limited Genetic Variation [24]
RBM45 OTWTHD77 Limited Biomarker [248]
RDX OTNSYUN6 Limited Genetic Variation [24]
REG1A OTMHUH1D Limited Biomarker [26]
REV3L OT0OP8EJ Limited Genetic Variation [244]
RMI2 OTA0HP4S Limited Genetic Variation [24]
RNF114 OTF06FRP Limited Biomarker [249]
RNF145 OTBCTG4A Limited Genetic Variation [23]
RPS26 OTBYTA6A Limited Genetic Variation [25]
SBNO2 OT1C6J3K Limited Genetic Variation [24]
SCRN1 OTELM5C2 Limited Genetic Variation [23]
SETD1A OTVVWRIC Limited Genetic Variation [24]
SKAP2 OTSF44KP Limited Genetic Variation [24]
SLIT3 OTU8MKEU Limited Genetic Variation [25]
SON OT9VWV18 Limited Genetic Variation [23]
SP140 OTQZHFMT Limited Genetic Variation [24]
STK11 OT1YZSP3 Limited Genetic Variation [24]
STX1B OTSW59X0 Limited Genetic Variation [244]
SYNE2 OTBUXGQ0 Limited Genetic Variation [23]
THADA OTYZQX0F Limited Genetic Variation [24]
TMEM258 OTXSDU14 Limited Genetic Variation [24]
TRIM65 OTSQTK3A Limited Genetic Variation [28]
TSPAN14 OT29167O Limited Genetic Variation [24]
ADCY7 OTAWMGP3 moderate Genetic Variation [39]
ADGRL2 OTCXD2YR moderate Genetic Variation [39]
ANKRD30A OTJXYAE5 moderate Genetic Variation [39]
ATXN2L OTP5M3R9 moderate Genetic Variation [39]
CRB1 OTXYUNG0 moderate Genetic Variation [39]
FNBP1 OTSJ5KKA moderate Genetic Variation [39]
INS-IGF2 OTZR74BO moderate Genetic Variation [39]
LURAP1L OTSJ29M5 moderate Genetic Variation [39]
NKD1 OTY3MO97 moderate Genetic Variation [39]
SUOX OTEJQ9FC moderate Genetic Variation [39]
AATK OTVHAX5N Strong Genetic Variation [250]
ACD OTC54EPO Strong Biomarker [251]
ACKR2 OTWYY14H Strong Biomarker [252]
ACOT8 OTHY684G Strong Altered Expression [253]
AIM2 OT86QUI8 Strong Biomarker [254]
ALOX15B OTWQQ08W Strong Genetic Variation [50]
ANGPTL6 OTOQ5W67 Strong Biomarker [255]
ANKRD55 OT62KZII Strong Genetic Variation [24]
ANXA6 OT9KIQ0Y Strong Genetic Variation [25]
ARHGEF2 OTBQTFRT Strong Biomarker [138]
ARMH1 OTTJC0D6 Strong Biomarker [138]
ATP5F1A OT3FZDLX Strong Biomarker [256]
AZI2 OT61Q7Q8 Strong Altered Expression [253]
B3GNT2 OTE69HV8 Strong Altered Expression [257]
B3GNTL1 OTYWGHF1 Strong Altered Expression [257]
BAIAP3 OTS1H0J0 Strong Altered Expression [258]
BANK1 OTXAAA11 Strong Genetic Variation [24]
BCAP31 OTKSACR4 Strong Altered Expression [259]
BCL10 OT47MCLI Strong Altered Expression [147]
BCL3 OT1M5B95 Strong Biomarker [260]
BTD OTJYTQ69 Strong Altered Expression [258]
BTNL2 OTTTEMZA Strong Genetic Variation [261]
BTRC OT2EZDGR Strong Biomarker [262]
C16orf82 OT77Z5Y5 Strong Biomarker [54]
CADM2 OT45PVKC Strong Genetic Variation [263]
CALML5 OTOFJLFA Strong Biomarker [241]
CBLIF OTNE20WU Strong Altered Expression [264]
CCL19 OTQ2UJMH Strong Biomarker [265]
CCL4 OT6B8P25 Strong Biomarker [102]
CCL4L2 OTDBSXOU Strong Biomarker [102]
CCL7 OTDIS99H Strong Biomarker [266]
CCR10 OT7ZWSSD Strong Biomarker [267]
CCRL2 OT5PX0RX Strong Genetic Variation [97]
CD1B OT4D5EG7 Strong Biomarker [268]
CD1C OT4XINUJ Strong Biomarker [268]
CD1D OT3ROU4J Strong Biomarker [269]
CD226 OT4UG0KB Strong Genetic Variation [24]
CD244 OTSMR85N Strong Biomarker [270]
CD84 OTAY5B0F Strong Genetic Variation [271]
CD93 OT6HZT6H Strong Genetic Variation [272]
CDC6 OTX93FE7 Strong Altered Expression [273]
CDCA5 OTZLCQ5U Strong Biomarker [77]
CDKAL1 OTA0SGNE Strong Genetic Variation [24]
CEBPD OTNBIPMY Strong Biomarker [274]
CETN1 OTGQ8JOZ Strong Altered Expression [275]
CHI3L1 OT2Z7VJH Strong Biomarker [153]
CKLF OTHLPHA0 Strong Biomarker [276]
CLC OTYMYR85 Strong Genetic Variation [277]
CLDN3 OT71MN9S Strong Biomarker [278]
CLEC7A OTRTBH27 Strong Biomarker [279]
CLMN OT7U5J3T Strong Biomarker [102]
CNTN3 OTC1274J Strong Biomarker [280]
COG6 OTDLQITC Strong Genetic Variation [281]
COPE OTBKHBT7 Strong Biomarker [282]
CP OTM8JE4Y Strong Biomarker [283]
CPQ OTTNZNLD Strong Biomarker [284]
CRABP1 OTISDG5X Strong Biomarker [285]
CRNN OTAORBR4 Strong Altered Expression [286]
CSMD1 OTIVDSC4 Strong Genetic Variation [25]
CST6 OTZVHJTF Strong Altered Expression [86]
DDX39A OT0Z6E1K Strong Biomarker [157]
DDX39B OTEVCFVU Strong Biomarker [157]
DEFB104A OTLQZR6K Strong Altered Expression [287]
DGCR8 OT62LXE4 Strong Altered Expression [288]
DLAT OT9LBJVN Strong Biomarker [289]
DMKN OTRIGZMK Strong Biomarker [290]
DMXL2 OTB4JWN3 Strong Biomarker [291]
DUOX1 OTQ2AEW0 Strong Biomarker [292]
EBNA1BP2 OTBRVMZH Strong Biomarker [138]
ECM1 OT1K65VW Strong Biomarker [51]
EDA OTAKS5WS Strong Altered Expression [293]
EDIL3 OTDVVNS0 Strong Biomarker [51]
EHF OTY6TPWD Strong Biomarker [106]
EMP1 OTSZHUHQ Strong Altered Expression [294]
ETFA OTXX61VZ Strong Biomarker [295]
FABP7 OTRE2H4G Strong Altered Expression [182]
FAM20B OTOA0UYT Strong Biomarker [296]
FANCE OTKRPBW1 Strong Biomarker [297]
FBXL19 OTGDHPOE Strong Genetic Variation [25]
FCGR3B OTSLSPZG Strong Biomarker [298]
FCN2 OTTHJBKZ Strong Biomarker [77]
FGD5 OT5VIRP2 Strong Altered Expression [193]
FNDC3A OTUX3S2I Strong Genetic Variation [24]
FUT2 OTLXM6WI Strong Biomarker [299]
FYCO1 OTKZHTZ5 Strong Biomarker [300]
FZD2 OT952ML1 Strong Genetic Variation [301]
FZD5 OTXFFY56 Strong Biomarker [302]
FZD8 OTZ9IRFL Strong Biomarker [302]
GALR3 OTXU6PKO Strong Biomarker [303]
GCHFR OTEOT8GI Strong Biomarker [77]
GLIS1 OTBDNB26 Strong Altered Expression [304]
GNLY OTZJKA8C Strong Biomarker [305]
GOT2 OT6XBWN0 Strong Biomarker [100]
GPR15 OTK8674M Strong Biomarker [306]
GPRC5A OTPOCWR7 Strong Altered Expression [307]
GRHL3 OT1V4ZEH Strong Altered Expression [308]
GSTK1 OTDNGWAF Strong Genetic Variation [232]
GSTM2 OTG4WT05 Strong Genetic Variation [309]
GZMA OT43R33L Strong Biomarker [310]
HAT1 OT307KEN Strong Biomarker [311]
HCP5 OTV0YRI8 Strong Genetic Variation [312]
HLA-DMB OT17HGXJ Strong Biomarker [313]
HLA-DOA OTZE5Q7R Strong Genetic Variation [314]
HLA-DQA2 OT1DH0N9 Strong Genetic Variation [315]
HLA-DRB5 OTUX5TWM Strong Genetic Variation [237]
HLA-E OTX1CTFB Strong Biomarker [316]
HSPA14 OTZCA5LK Strong Altered Expression [317]
IARS1 OT9WXH5N Strong Biomarker [318]
ID4 OTPMJ39I Strong Posttranslational Modification [319]
IFI16 OT4SPU0U Strong Biomarker [320]
IFI27 OTI2XGIT Strong Biomarker [321]
IFI6 OTWOOAM4 Strong Altered Expression [322]
IFNLR1 OTWWWK45 Strong Biomarker [323]
IL12RB1 OTM1IJO2 Strong Biomarker [324]
IL17C OTKXIVNQ Strong Biomarker [325]
IL17RC OTEFOBSS Strong Altered Expression [326]
IL17RD OTKD9XST Strong Altered Expression [327]
IL1F10 OTJAASGC Strong Biomarker [328]
IL20RA OTSIVBVS Strong Genetic Variation [329]
IL20RB OTHFXK95 Strong Genetic Variation [329]
IL22RA1 OTGVKLBR Strong Altered Expression [330]
IL22RA2 OTGOFDCY Strong Biomarker [331]
IL26 OT2WYCW4 Strong Biomarker [332]
IL27 OTIS3OF8 Strong Biomarker [127]
IL36B OTYT4LP5 Strong Biomarker [93]
IL36RN OT5CO95A Strong Genetic Variation [333]
IL9R OTILCLXA Strong Altered Expression [334]
IRF2 OTAZRUW3 Strong Genetic Variation [335]
ISG20 OTCWRJJW Strong Biomarker [336]
ISYNA1 OT49ONSE Strong Genetic Variation [337]
ITGAX OTOGIMHE Strong Biomarker [338]
ITLN1 OT7ZLJVV Strong Genetic Variation [339]
IVL OT4VPNGY Strong Altered Expression [340]
JAM2 OTHVJJRJ Strong Biomarker [341]
JAZF1 OTXTYSYD Strong Genetic Variation [342]
JUNB OTG2JXV5 Strong Altered Expression [221]
KHDRBS3 OTUG02U7 Strong Altered Expression [294]
KIR2DL5A OT09FZE1 Strong Altered Expression [343]
KIR3DL1 OTPOSXFX Strong Biomarker [110]
KIR3DS1 OTJWIO4T Strong Genetic Variation [344]
KLK11 OT5PKX7Y Strong Altered Expression [142]
KLLN OTV3FPH0 Strong Biomarker [345]
KLRC2 OTT4N86S Strong Genetic Variation [316]
KRT10 OTSVRD3Q Strong Biomarker [346]
KRT14 OTUVZ1DW Strong Genetic Variation [347]
LCE3A OTOJUELU Strong Altered Expression [348]
LCE3D OTNAIJSE Strong Biomarker [349]
LHFPL6 OTY6LHJY Strong Genetic Variation [123]
LMO4 OT5NDCT9 Strong Biomarker [350]
LRRFIP1 OTN7XAUD Strong Biomarker [351]
LYNX1 OTK4103B Strong Biomarker [352]
MAVS OTTQ0J64 Strong Biomarker [246]
MED15 OT0D0JVD Strong Altered Expression [307]
MGAT5 OTU4DD4G Strong Biomarker [353]
MIB1 OT5C404P Strong Biomarker [152]
MMP19 OTLSTT2B Strong Altered Expression [354]
MNAT1 OTXLOYCB Strong Biomarker [77]
MOCOS OT0TL3Q5 Strong Genetic Variation [355]
MXRA7 OTVQLYIY Strong Biomarker [356]
MYOM2 OTD2UOXW Strong Biomarker [357]
NAA25 OTS3QVF1 Strong Altered Expression [253]
NANS OTMQ2FUH Strong Biomarker [358]
NAP1L1 OTI7WBZV Strong Altered Expression [253]
NAPSA OT6F8IAL Strong Altered Expression [253]
NAT9 OT4ZKCRS Strong Genetic Variation [359]
NBAS OTW9IBRI Strong Genetic Variation [154]
NCKAP1 OTEZQXXJ Strong Altered Expression [253]
NCOA5 OTOGWTWB Strong Genetic Variation [360]
NFATC1 OT4TMERS Strong Genetic Variation [24]
NFATC4 OTTDCUAO Strong Altered Expression [361]
NFKBIL1 OTYFTPS0 Strong Biomarker [362]
NLN OTFRITPU Strong Altered Expression [363]
NME2 OTCYGLHV Strong Altered Expression [364]
NRIP1 OTIZOJQV Strong Biomarker [365]
NRTN OT4PAKUY Strong Biomarker [366]
OAS2 OT64CCTM Strong Altered Expression [367]
OLIG3 OTU8XLAF Strong Biomarker [368]
OPN4 OT1LZ7TS Strong Altered Expression [363]
OPTC OTCASGO0 Strong Biomarker [369]
OR2AG1 OTEITRP4 Strong Genetic Variation [370]
ORM1 OTZKSBRE Strong Biomarker [256]
OSCP1 OTZ4IFGJ Strong Biomarker [371]
OXA1L OTS0BFRD Strong Biomarker [372]
PCDHGA12 OT3JJI7L Strong Altered Expression [373]
PCLAF OTMVIOUU Strong Biomarker [374]
PDC OT1UUVYY Strong Biomarker [211]
PDPN OTBUV19I Strong Biomarker [375]
PDZK1IP1 OTWA6M5K Strong Altered Expression [376]
PGLYRP1 OTBTPR2T Strong Genetic Variation [377]
PGLYRP3 OT5C7PRT Strong Genetic Variation [378]
PGLYRP4 OTI115BR Strong Genetic Variation [378]
PI3 OT47MTC3 Strong Altered Expression [379]
PIAS4 OTB7SVMZ Strong Genetic Variation [380]
PIK3IP1 OTWE5G4T Strong Biomarker [351]
PIPOX OTWTCOTN Strong Biomarker [381]
PLA2G10 OTRZ2L5A Strong Biomarker [382]
PLCD1 OT6WFVXZ Strong Biomarker [383]
PLXNB2 OT56I2VD Strong Biomarker [190]
PNISR OTUM02FW Strong Biomarker [384]
POMP OTMPM1P5 Strong Biomarker [385]
PPBP OT1FHGQS Strong Altered Expression [386]
PPP3R1 OTGQNFJQ Strong Biomarker [387]
PPP6C OTR1STMJ Strong Biomarker [388]
PRELP OT9EEBUJ Strong Altered Expression [294]
PRKRA OTUTVZZU Strong Genetic Variation [25]
PROK2 OT70IFEZ Strong Biomarker [389]
PRR9 OT4ZHG7T Strong Genetic Variation [390]
PSAP OTUOEKY7 Strong Altered Expression [391]
PSMD7 OT7PZZ4K Strong Biomarker [138]
PSORS1C1 OT9HK436 Strong Genetic Variation [392]
PSORS1C2 OTK43GE4 Strong Genetic Variation [393]
PTTG1 OTIMYS4W Strong Genetic Variation [45]
PTTG2 OTXGZ8FV Strong Biomarker [394]
PWP1 OTUKXP1E Strong Biomarker [395]
R3HCC1L OT776PX2 Strong Biomarker [396]
RAB40B OTCA9ZF5 Strong Genetic Variation [397]
RABEPK OTCZSREH Strong Biomarker [138]
RARRES1 OTETUPP5 Strong Altered Expression [307]
RARRES2 OT1BJE8K Strong Biomarker [398]
RBP1 OTRP1MFC Strong Biomarker [399]
RETN OTW5Z1NH Strong Altered Expression [400]
RNASE7 OTIXO0Z4 Strong Biomarker [401]
ROBO3 OTPVG40S Strong Biomarker [40]
RPA1 OT76POLP Strong Biomarker [402]
RTL1 OTOT33IM Strong Biomarker [403]
S100A14 OTVFJJ91 Strong Altered Expression [275]
SAA2 OTYAVJWG Strong Altered Expression [185]
SCN7A OTK05PXY Strong Genetic Variation [154]
SCUBE1 OT4JY1UY Strong Altered Expression [404]
SDF4 OTQ7WFYW Strong Altered Expression [275]
SERPINB1 OT5RDUFO Strong Altered Expression [229]
SERPINB4 OT88LHZ8 Strong Biomarker [225]
SERPINB8 OT5T4Y5R Strong Biomarker [405]
SETMAR OTE2MIMZ Strong Biomarker [403]
SH3BP4 OTVIRKW7 Strong Biomarker [406]
SHARPIN OTU1J2KH Strong Biomarker [407]
SHBG OTPWU5IW Strong Genetic Variation [52]
SLURP1 OT89YD2E Strong Biomarker [408]
SLURP2 OTDWAJ2O Strong Biomarker [352]
SMCP OTXKY794 Strong Genetic Variation [355]
SNRNP70 OTP52YZ3 Strong Genetic Variation [409]
SOD3 OTIOZQAB Strong Altered Expression [410]
SPATA2 OTOA45GL Strong Genetic Variation [25]
SPINK5 OT61IIAO Strong Altered Expression [411]
SPINK7 OTK3VOI3 Strong Altered Expression [412]
SPRED1 OTKX7P8G Strong Genetic Variation [413]
SRF OTW18FQN Strong Biomarker [414]
STAT2 OTO9G2RZ Strong Biomarker [89]
STAT4 OTAK3VFR Strong Altered Expression [415]
STK40 OT4R325X Strong Biomarker [416]
SUCO OT3I9VO9 Strong Biomarker [369]
SUGP1 OT7W0EB8 Strong Biomarker [154]
TAB3 OT1ECMDL Strong Altered Expression [253]
TAC1 OTM842YW Strong Biomarker [62]
TACC2 OTW4M7HI Strong Biomarker [294]
TAGAP OTHJNNO2 Strong Biomarker [417]
TANK OTZSGFIK Strong Biomarker [195]
TBCC OTBF0X8R Strong Genetic Variation [418]
TCAIM OTOBD7YO Strong Altered Expression [419]
TCF19 OT7NKLF9 Strong Biomarker [420]
TEPSIN OTJIVR84 Strong Genetic Variation [250]
TES OTL8PP6V Strong Biomarker [421]
TFIP11 OT7NVSWU Strong Biomarker [160]
TIMP4 OT8A68SW Strong Biomarker [153]
TLCD3B OTM6EPUS Strong Altered Expression [422]
TLE1 OT50MRZ1 Strong Biomarker [423]
TNFAIP8L2 OTII0RM0 Strong Biomarker [424]
TNFRSF6B OTKAN9G7 Strong Genetic Variation [24]
TNFSF8 OTDYGDJ3 Strong Biomarker [425]
TNNT1 OT8PBOAR Strong Biomarker [54]
TPM1 OTD73X6R Strong Posttranslational Modification [426]
TPM2 OTA1L0P8 Strong Altered Expression [426]
TRAF3IP2 OTLLZERL Strong Genetic Variation [427]
TRAIP OTMPT9Y2 Strong Biomarker [351]
TREX1 OTQG7K12 Strong Altered Expression [428]
TREX2 OT5QAGJ4 Strong Altered Expression [429]
TRIM21 OTA4UJCF Strong Biomarker [430]
TRIM32 OTJOV0PG Strong Altered Expression [431]
TRMO OTNJ7K9K Strong Altered Expression [253]
TSC22D3 OT03UM03 Strong Biomarker [432]
TSPAN31 OT8WQ83R Strong Biomarker [358]
TTC7A OTDHLPQM Strong Genetic Variation [433]
ADAMTSL5 OTQAGNQP Definitive Biomarker [434]
CD79A OTOJC8DV Definitive Biomarker [435]
CSTA OT1K68KE Definitive Biomarker [229]
CXCL17 OTRCEVIZ Definitive Altered Expression [436]
FLNB OTPCOYL6 Definitive Genetic Variation [172]
KRT16 OTGA0EQN Definitive Biomarker [437]
MTX1 OTLSDNZO Definitive Biomarker [438]
MYDGF OT9HRPL6 Definitive Biomarker [127]
NFKBIZ OTU728KS Definitive Altered Expression [439]
NXF1 OTEFHXG6 Definitive Genetic Variation [172]
PLAAT4 OTI66SAJ Definitive Biomarker [440]
S100A1 OT1F2G4J Definitive Genetic Variation [441]
S100A7A OTNM8DCP Definitive Biomarker [442]
SEC14L2 OTJST64D Definitive Genetic Variation [172]
SOAT1 OTB4Y5RJ Definitive Biomarker [443]
SYNGR1 OT0MBUK5 Definitive Genetic Variation [281]
TIMP3 OTDGQAD1 Definitive Biomarker [444]
TNXB OTVBWAV5 Definitive Biomarker [445]
------------------------------------------------------------------------------------
⏷ Show the Full List of 407 DOT(s)

References

1 Atorvastatin FDA Label
2 Betamethasone FDA Label
3 Calcipotriol and psoriasis. Int J Dermatol. 1992 Aug;31(8):549-50.
4 Cortisone acetate FDA Label
5 Dexamethasone FDA Label
6 Erlotinib FDA Label
7 Hydrocortisone FDA Label
8 Methotrexate FDA Label
9 Methylprednisolone FDA Label
10 Co-delivery of methotrexate and nicotinamide by cerosomes for topical psoriasis treatment with enhanced efficacy. Int J Pharm. 2021 Aug 10;605:120826.
11 Prednisolone FDA Label
12 Prednisone FDA Label
13 Tazarotene FDA Label
14 Triamcinolone FDA Label
15 Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1). Lancet. 2008 May 17;371(9625):1665-74.
16 Cosmeceutical Aptitudes of Niacinamide: A Review. Recent Adv Antiinfect Drug Discov. 2021;16(3):196-208.
17 A review of antibiotics and psoriasis: induction, exacerbation, and amelioration. Expert Rev Clin Pharmacol. 2019 Oct;12(10):981-989.
18 Pustular psoriasis. Cutis. 1993 Jan;51(1):29-32.
19 ClinicalTrials.gov (NCT05223868) A Phase 2b Multicenter, Randomized, Placebo Controlled, Dose-ranging Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Moderate-to-Severe Plaque Psoriasis. U.S.National Institutes of Health.
20 ClinicalTrials.gov (NCT05375955) A PHASE 2B, RANDOMIZED, DOUBLE BLIND, VEHICLE CONTROLLED, PARALLEL GROUP STUDY TO ASSESS THE EFFICACY, SAFETY, TOLERABILITY AND PHARMACOKINETICS OF MULTIPLE DOSE LEVELS OF PF-07038124 OINTMENT FOR 12 WEEKS IN PARTICIPANTS 12 YEARS AND OLDER AND WITH MILD-TO-MODERATE ATOPIC DERMATITIS OR MILD-TO-SEVERE PLAQUE PSORIASIS. U.S.National Institutes of Health.
21 Clinical pipeline report, company report or official report of JOHNSON & JOHNSON
22 Clinical pipeline report, company report or official report of Dyve Biosciences
23 Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis.Nat Commun. 2015 Apr 9;6:6793. doi: 10.1038/ncomms7793.
24 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.Nat Genet. 2016 May;48(5):510-8. doi: 10.1038/ng.3528. Epub 2016 Mar 14.
25 Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.Am J Hum Genet. 2015 Jan 8;96(1):104-20. doi: 10.1016/j.ajhg.2014.12.004.
26 Tildrakizumab: A Review in Moderate-to-Severe Plaque Psoriasis.Am J Clin Dermatol. 2019 Apr;20(2):295-306. doi: 10.1007/s40257-019-00435-9.
27 A genetic coding variant rs72474224 in GJB2 is associated with clinical features of psoriasis vulgaris in a Chinese Han population.Tissue Antigens. 2015 Aug;86(2):134-8. doi: 10.1111/tan.12595. Epub 2015 Jun 24.
28 Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.Nat Commun. 2017 May 24;8:15382. doi: 10.1038/ncomms15382.
29 HLA Correlations with Clinical Phenotypes and Risk of Metabolic Comorbidities in Singapore Chinese Psoriasis Patients.Mol Diagn Ther. 2019 Dec;23(6):751-760. doi: 10.1007/s40291-019-00423-z.
30 Association between psoriasis vulgaris and MHC-DRB, -DQB genes as a contribution to disease diagnosis.Eur J Dermatol. 2005 May-Jun;15(3):159-63.
31 Trans-presentation of interleukin-15 by interleukin-15 receptor alpha is dispensable for the pathogenesis of autoimmune type 1 diabetes.Cell Mol Immunol. 2017 Jul;14(7):590-596. doi: 10.1038/cmi.2015.102. Epub 2016 Feb 8.
32 Assessment and Clinical Relevance of Serum IL-19 Levels in Psoriasis and Atopic Dermatitis Using a Sensitive and Specific Novel Immunoassay.Sci Rep. 2019 Mar 26;9(1):5211. doi: 10.1038/s41598-019-41609-z.
33 IL-20 bone diseases involvement and therapeutic target potential.J Biomed Sci. 2018 Apr 24;25(1):38. doi: 10.1186/s12929-018-0439-z.
34 Clinical significance and immunobiology of IL-21 in autoimmunity.J Autoimmun. 2019 May;99:1-14. doi: 10.1016/j.jaut.2019.01.013. Epub 2019 Feb 14.
35 The PDE4 inhibitor CHF6001 modulates pro-inflammatory cytokines, chemokines and Th1- and Th17-polarizing cytokines in human dendritic cells.Biochem Pharmacol. 2019 May;163:371-380. doi: 10.1016/j.bcp.2019.03.006. Epub 2019 Mar 6.
36 Peroxisome Proliferator-Activated Receptor- Gene Polymorphism in Psoriasis and Its Relation to Obesity, Metabolic Syndrome, and Narrowband Ultraviolet B Response: A Case-Control Study in Egyptian Patients.Indian J Dermatol. 2019 May-Jun;64(3):192-200. doi: 10.4103/ijd.IJD_114_18.
37 Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.Am J Hum Genet. 2015 Dec 3;97(6):816-36. doi: 10.1016/j.ajhg.2015.10.019. Epub 2015 Nov 28.
38 Rutaecarpine inhibited imiquimod-induced psoriasis-like dermatitis via inhibiting the NF-B and TLR7 pathways in mice.Biomed Pharmacother. 2019 Jan;109:1876-1883. doi: 10.1016/j.biopha.2018.10.062. Epub 2018 Nov 26.
39 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.Nat Med. 2015 Sep;21(9):1018-27. doi: 10.1038/nm.3933. Epub 2015 Aug 24.
40 Gene expression profiling reveals the role of RIG1 like receptor signaling in p53 dependent apoptosis induced by PUVA in keratinocytes.Cell Signal. 2016 Jan;28(1):25-33. doi: 10.1016/j.cellsig.2015.10.015. Epub 2015 Oct 27.
41 MiR-21 binding site SNP within ITGAM associated with psoriasis susceptibility in women.PLoS One. 2019 Jun 18;14(6):e0218323. doi: 10.1371/journal.pone.0218323. eCollection 2019.
42 Angiotensin-converting enzyme insertion/deletion polymorphism and susceptibility to psoriasis in a Chinese population.J Renin Angiotensin Aldosterone Syst. 2014 Mar;15(1):39-43. doi: 10.1177/1470320313494433. Epub 2013 Jul 11.
43 The role of the Duffy antigen-related chemokine receptor in psoriasis vulgaris.Cytokine. 2002 Jun 21;18(6):329-33. doi: 10.1006/cyto.2002.0878.
44 Association of ADAM33 gene polymorphisms with psoriasis in a northeastern Chinese population.Mol Biol Rep. 2014 Jun;41(6):4001-5. doi: 10.1007/s11033-014-3268-5. Epub 2014 Feb 22.
45 Fine mapping and subphenotyping implicates ADRA1B gene variants in psoriasis susceptibility in a Chinese population.Epigenomics. 2019 Feb;11(4):455-467. doi: 10.2217/epi-2018-0131. Epub 2019 Feb 20.
46 Topical administration of reversible SAHH inhibitor ameliorates imiquimod-induced psoriasis-like skin lesions in mice via suppression of TNF-/IFN--induced inflammatory response in keratinocytes and T cell-derived IL-17.Pharmacol Res. 2018 Mar;129:443-452. doi: 10.1016/j.phrs.2017.11.012. Epub 2017 Nov 14.
47 Aryl hydrocarbon receptor polymorphisms are associated with dry skin phenotypes in Chinese patients with atopic dermatitis.Clin Exp Dermatol. 2019 Aug;44(6):613-619. doi: 10.1111/ced.13841. Epub 2018 Nov 29.
48 Ascorbic acid derivative DDH-1 ameliorates psoriasis-like skin lesions in mice by suppressing inflammatory cytokine expression.J Pharmacol Sci. 2018 Dec;138(4):284-288. doi: 10.1016/j.jphs.2018.11.002. Epub 2018 Nov 20.
49 MiR-125b-5p and miR-181b-5p inhibit keratinocyte proliferation in skin by targeting Akt3.Eur J Pharmacol. 2019 Nov 5;862:172659. doi: 10.1016/j.ejphar.2019.172659. Epub 2019 Sep 10.
50 Lack of association of ALOX12 and ALOX15B polymorphisms with psoriasis despite altered urinary excretion of 12(S)-hydroxyeicosatetraenoic acid.Br J Dermatol. 2015 Feb;172(2):337-44. doi: 10.1111/bjd.13225. Epub 2014 Nov 30.
51 mRNA and protein expression of the angiogenesis-related genes EDIL3, AMOT and ECM1 in mesenchymal stem cells in psoriatic dermis.Clin Exp Dermatol. 2016 Jul;41(5):533-40. doi: 10.1111/ced.12783. Epub 2015 Dec 8.
52 Clinical similarity of biosimilar ABP 501 to adalimumab in the treatment of patients with moderate to severe plaque psoriasis: A randomized, double-blind, multicenter, phase III study.J Am Acad Dermatol. 2017 Jun;76(6):1093-1102. doi: 10.1016/j.jaad.2016.12.014. Epub 2017 Mar 11.
53 Methylentetrahydrofolatereductase (rs1801133) polymorphism and psoriasis: contribution to oxidative stress, lipid peroxidation and correlation with vascular adhesion protein 1, preliminary report.J Eur Acad Dermatol Venereol. 2014 Sep;28(9):1192-8. doi: 10.1111/jdv.12262. Epub 2013 Sep 30.
54 Effectiveness of Lipid-Lowering Statin Therapy in Patients With and Without Psoriasis.Clin Drug Investig. 2017 Aug;37(8):775-785. doi: 10.1007/s40261-017-0533-0.
55 Apolipoprotein E gene polymorphism and serum lipid profile in Saudi patients with psoriasis.Dis Markers. 2014;2014:239645. doi: 10.1155/2014/239645. Epub 2014 Mar 23.
56 Yes-associated protein promotes the abnormal proliferation of psoriatic keratinocytes via an amphiregulin dependent pathway.Sci Rep. 2018 Oct 15;8(1):14513. doi: 10.1038/s41598-018-32522-y.
57 HIF-1-mediated BMP6 down-regulation leads to hyperproliferation and abnormal differentiation of keratinocytes in vitro.Exp Dermatol. 2018 Nov;27(11):1287-1293. doi: 10.1111/exd.13785. Epub 2018 Oct 9.
58 Nonclinical Safety and Toxicokinetics of MnTE-2-PyP (BMX-010), a Topical Agent in Phase 2 Trials for Psoriasis and Atopic Dermatitis.Int J Toxicol. 2019 Jul/Aug;38(4):291-302. doi: 10.1177/1091581819852325.
59 Antiviral gene expression in psoriasis.J Eur Acad Dermatol Venereol. 2015 Oct;29(10):1951-7. doi: 10.1111/jdv.13091. Epub 2015 Mar 23.
60 C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.Front Immunol. 2019 Aug 7;10:1866. doi: 10.3389/fimmu.2019.01866. eCollection 2019.
61 Lack of association between leptin, leptin receptor, adiponectin gene polymorphisms and epicardial adipose tissue, abdominal visceral fat volume and atherosclerotic burden in psoriasis patients.Arch Physiol Biochem. 2015;121(3):103-8. doi: 10.3109/13813455.2015.1024136. Epub 2015 Jun 30.
62 Clearance of psoriasis after ischemic stroke.Cutis. 2019 Feb;103(2):74-76.
63 Human S100A7 Induces Mature Interleukin1 Expression by RAGE-p38 MAPK-Calpain1 Pathway in Psoriasis.PLoS One. 2017 Jan 6;12(1):e0169788. doi: 10.1371/journal.pone.0169788. eCollection 2017.
64 Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.Nat Genet. 2012 Dec;44(12):1341-8. doi: 10.1038/ng.2467. Epub 2012 Nov 11.
65 Th17 micro-milieu regulates NLRP1-dependent caspase-5 activity in skin autoinflammation.PLoS One. 2017 Apr 19;12(4):e0175153. doi: 10.1371/journal.pone.0175153. eCollection 2017.
66 Association of total oxidant status, total antioxidant status, and malondialdehyde and catalase levels with psoriasis: a systematic review and meta-analysis.Clin Rheumatol. 2019 Oct;38(10):2659-2671. doi: 10.1007/s10067-019-04676-1. Epub 2019 Jul 18.
67 Association of GA genotype of SNP rs4680 in COMT gene with psoriasis.Arch Dermatol Res. 2019 May;311(4):309-315. doi: 10.1007/s00403-019-01904-1. Epub 2019 Mar 6.
68 Alteration of serum thymus and activation-regulated chemokine level during biologic therapy for psoriasis: Possibility as a marker reflecting favorable response to anti-interleukin-17A agents.J Dermatol. 2018 Jun;45(6):710-714. doi: 10.1111/1346-8138.14308. Epub 2018 Apr 14.
69 The CCL20 and CCR6 axis in psoriasis.Scand J Immunol. 2020 Mar;91(3):e12846. doi: 10.1111/sji.12846. Epub 2019 Nov 24.
70 Potential role of the chemokine receptors CXCR3, CCR4, and the integrin alphaEbeta7 in the pathogenesis of psoriasis vulgaris.Lab Invest. 2001 Mar;81(3):335-47. doi: 10.1038/labinvest.3780242.
71 A role for CCR5(+)CD4 T cells in cutaneous psoriasis and for CD103(+) CCR4(+) CD8 Teff cells in the associated systemic inflammation.J Autoimmun. 2016 Jun;70:80-90. doi: 10.1016/j.jaut.2016.03.019. Epub 2016 Apr 8.
72 Eczema in Psoriatico: An Important Differential Diagnosis Between Chronic Allergic Contact Dermatitis and Psoriasis in Palmoplantar Localization.Acta Derm Venereol. 2018 Jan 12;98(1):50-58. doi: 10.2340/00015555-2779.
73 CD200-CD200R1 signalling attenuates imiquimod-induced psoriatic inflammation by inhibiting the activation of skin inflammatory macrophages.Int Immunopharmacol. 2020 Jan;78:106046. doi: 10.1016/j.intimp.2019.106046. Epub 2019 Dec 10.
74 IL-10 producing Bregs are impaired in psoriatic arthritis and psoriasis and inversely correlate with IL-17- and IFN-producing T cells.Clin Immunol. 2017 Nov;184:33-41. doi: 10.1016/j.clim.2017.04.010. Epub 2017 Apr 28.
75 Superiority of a vitamin B(12)-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasis.Int J Immunopathol Pharmacol. 2017 Dec;30(4):439-444. doi: 10.1177/0394632017736674. Epub 2017 Oct 19.
76 Vitiligo Skin Is Imprinted with Resident Memory CD8 T Cells Expressing CXCR3.J Invest Dermatol. 2018 Feb;138(2):355-364. doi: 10.1016/j.jid.2017.08.038. Epub 2017 Sep 18.
77 Clinical Significance of Decreased Interleukin-35 Expression in Patients with Psoriasis.Microbiol Immunol. 2018 May 26. doi: 10.1111/1348-0421.12605. Online ahead of print.
78 Allelic distribution of complement components BF, C4A, C4B, and C3 in Psoriasis vulgaris.Immunol Lett. 2002 Mar 1;80(3):145-9. doi: 10.1016/s0165-2478(01)00317-0.
79 The discovery and optimization of a series of 2-aminobenzoxazole derivatives as ChemR23 inhibitors.Bioorg Med Chem. 2019 Nov 1;27(21):115091. doi: 10.1016/j.bmc.2019.115091. Epub 2019 Sep 6.
80 S100A7, Jab1, and p27(kip1) expression in psoriasis and S100A7 CRISPR-activated human keratinocyte cell line.J Cell Biochem. 2019 Mar;120(3):3384-3392. doi: 10.1002/jcb.27609. Epub 2018 Sep 11.
81 The association of PASI scores with CRH-R1 expression in patients with psoriasis.Arch Dermatol Res. 2012 Mar;304(2):127-32. doi: 10.1007/s00403-012-1218-4. Epub 2012 Feb 15.
82 Analysis of genetic variants of class II cytokine and their receptor genes in psoriasis patients of two ethnic groups from the Volga-Ural region of Russia.J Dermatol Sci. 2012 Oct;68(1):9-18. doi: 10.1016/j.jdermsci.2012.07.002. Epub 2012 Jul 16.
83 Granulocyte-macrophage colony-stimulating factor (GM-CSF) as a therapeutic target in psoriasis: randomized, controlled investigation using namilumab, a specific human anti-GM-CSF monoclonal antibody.Br J Dermatol. 2019 Jun;180(6):1352-1360. doi: 10.1111/bjd.17195. Epub 2018 Nov 2.
84 Cathepsin G cleaves and activates IL-36 and promotes the inflammation of psoriasis.Drug Des Devel Ther. 2019 Feb 8;13:581-588. doi: 10.2147/DDDT.S194765. eCollection 2019.
85 Differential effects of specific cathepsin S inhibition in biocompartments from patients with primary Sjgren syndrome.Arthritis Res Ther. 2019 Jul 18;21(1):175. doi: 10.1186/s13075-019-1955-2.
86 The cystatin M/E-controlled pathway of skin barrier formation: expression of its key components in psoriasis and atopic dermatitis.Br J Dermatol. 2009 Aug;161(2):253-64. doi: 10.1111/j.1365-2133.2009.09156.x. Epub 2009 Apr 24.
87 CX3CR1 deficiency attenuates imiquimod-induced psoriasis-like skin inflammation with decreased M1 macrophages.J Dermatol Sci. 2016 Jun;82(3):175-88. doi: 10.1016/j.jdermsci.2016.03.004. Epub 2016 Mar 4.
88 Elevated circulating levels of the interferon--induced chemokines are associated with disease activity and cutaneous manifestations in adult-onset Still's disease.Sci Rep. 2017 Apr 24;7:46652. doi: 10.1038/srep46652.
89 STAT2 is involved in the pathogenesis of psoriasis by promoting CXCL11 and CCL5 production by keratinocytes.PLoS One. 2017 May 4;12(5):e0176994. doi: 10.1371/journal.pone.0176994. eCollection 2017.
90 Circulating levels of chemokines in patients with psoriasis vulgaris and their association with disease severity: A case-control study from North India.Indian J Dermatol Venereol Leprol. 2019 Sep-Oct;85(5):567. doi: 10.4103/ijdvl.IJDVL_392_18.
91 The development and characterization of an in vitro model of psoriasis.J Invest Dermatol. 2004 Nov;123(5):892-901. doi: 10.1111/j.0022-202X.2004.23435.x.
92 CYP24 inhibition as a therapeutic target in FGF23-mediated renal phosphate wasting disorders.J Clin Invest. 2016 Feb;126(2):667-80. doi: 10.1172/JCI81928. Epub 2016 Jan 19.
93 Ichthyosis molecular fingerprinting shows profound T(H)17 skewing and a unique barrier genomic signature.J Allergy Clin Immunol. 2019 Feb;143(2):604-618. doi: 10.1016/j.jaci.2018.03.021. Epub 2018 May 24.
94 MAPK Phosphatase-1 Deficiency Exacerbates the Severity of Imiquimod-Induced Psoriasiform Skin Disease.Front Immunol. 2018 Mar 21;9:569. doi: 10.3389/fimmu.2018.00569. eCollection 2018.
95 Protective effect of human endogenous retrovirus K dUTPase variants on psoriasis susceptibility.J Invest Dermatol. 2012 Jul;132(7):1833-40. doi: 10.1038/jid.2012.69. Epub 2012 Mar 22.
96 Effect of psoriasis activity and topical treatment on plasma epidermal growth factor (EGF) and its soluble receptor (sEGFR).J Dermatolog Treat. 2018 Mar;29(2):135-139. doi: 10.1080/09546634.2017.1343933. Epub 2017 Jul 6.
97 CCHCR1 is up-regulated in skin cancer and associated with EGFR expression.PLoS One. 2009 Jun 24;4(6):e6030. doi: 10.1371/journal.pone.0006030.
98 The association of ERAP1 and ERAP2 single nucleotide polymorphisms and their haplotypes with psoriasis vulgaris is dependent on the presence or absence of the HLA-C*06:02 allele and age at disease onset.Hum Immunol. 2018 Feb;79(2):109-116. doi: 10.1016/j.humimm.2017.11.010. Epub 2017 Nov 26.
99 Human immunodeficiency virus (HIV) transcripts identified in HIV-related psoriasis and Kaposi's sarcoma lesions.J Clin Invest. 1991 Jul;88(1):174-85. doi: 10.1172/JCI115275.
100 Liver fatty acid-binding protein might be a predictive marker of clinical response to systemic treatment in psoriasis.Arch Dermatol Res. 2019 Jul;311(5):389-397. doi: 10.1007/s00403-019-01917-w. Epub 2019 Apr 16.
101 Adipocyte Fatty Acid-Binding Protein as a Novel Marker of Psoriasis and Clinical Response to Acitretin.Lipids. 2019 Aug;54(8):445-452. doi: 10.1002/lipd.12173. Epub 2019 Jul 8.
102 Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis.J Immunol Res. 2015;2015:101879. doi: 10.1155/2015/101879. Epub 2015 Nov 3.
103 Decreased expression of G-protein-coupled receptors GPR43 and GPR109a in psoriatic skin can be restored by topical application of sodium butyrate.Arch Dermatol Res. 2018 Nov;310(9):751-758. doi: 10.1007/s00403-018-1865-1. Epub 2018 Sep 12.
104 FGF19 sustains the high proliferative ability of keratinocytes in psoriasis through the regulation of Wnt/GSK-3/-catenin signalling via FGFR4.Clin Exp Pharmacol Physiol. 2019 Aug;46(8):761-769. doi: 10.1111/1440-1681.13103. Epub 2019 Jun 3.
105 Serum vascular endothelial growth factor receptor 3 as a potential biomarker in psoriasis.Exp Dermatol. 2018 Sep;27(9):1053-1057. doi: 10.1111/exd.13727. Epub 2018 Jul 29.
106 Integrated analysis of gene expression profiles identifies transcription factors potentially involved in psoriasis pathogenesis.J Cell Biochem. 2019 Aug;120(8):12582-12594. doi: 10.1002/jcb.28525. Epub 2019 Mar 1.
107 Lymphocyte mass cytometry identifies a CD3-CD4+ cell subset with a potential role in psoriasis.JCI Insight. 2019 Mar 21;4(6):e125306. doi: 10.1172/jci.insight.125306. eCollection 2019 Mar 21.
108 Serum amyloid A, an acute phase protein, stimulates proliferative and proinflammatory responses of keratinocytes.Cell Prolif. 2017 Jun;50(3):e12320. doi: 10.1111/cpr.12320. Epub 2016 Dec 2.
109 PACE study: real-life Psoriasis Area and Severity Index (PASI) 100 response with biological agents in moderate-severe psoriasis.J Dermatolog Treat. 2018 Aug;29(5):481-486. doi: 10.1080/09546634.2017.1395805. Epub 2017 Nov 10.
110 The Presence of HLA-A Bw4-80I KIR Ligands Could Predict "Difficult-to-Treat" Psoriasis and Poor Response to Etanercept.Mol Diagn Ther. 2018 Aug;22(4):471-474. doi: 10.1007/s40291-018-0345-9.
111 Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms.Br J Dermatol. 2009 Feb;160(2):438-41. doi: 10.1111/j.1365-2133.2008.08898.x. Epub 2008 Oct 25.
112 MicroRNA-194 regulates keratinocyte proliferation and differentiation by targeting Grainyhead-like 2 in psoriasis.Pathol Res Pract. 2017 Feb;213(2):89-97. doi: 10.1016/j.prp.2016.11.020. Epub 2016 Dec 19.
113 Expression of epidermal N-methyl-D-aspartate receptors (NMDAR1) depends on formation of the granular layer--analysis in diseases with parakeratotic cornification.Arch Dermatol Res. 2004 Sep;296(4):157-62. doi: 10.1007/s00403-004-0505-0.
114 [HAX-1 protein: multifunctional factor involved in apoptosis, cell migration, endocytosis and mRNA transport].Postepy Biochem. 2007;53(3):218-27.
115 PPARdelta enhances keratinocyte proliferation in psoriasis and induces heparin-binding EGF-like growth factor.J Invest Dermatol. 2008 Jan;128(1):110-24. doi: 10.1038/sj.jid.5700943. Epub 2007 Jul 19.
116 Autoimmunitt gegen heterogenes nukleres Ribonukleoprotein A1 bei Psoriasispatienten und Korrelation mit dem Schweregrad der Erkrankung.J Dtsch Dermatol Ges. 2018 Sep;16(9):1103-1108. doi: 10.1111/ddg.13631_g.
117 Silencing of homeobox A5 gene in the stratum corneum of psoriasis.Exp Dermatol. 2017 Nov;26(11):1068-1074. doi: 10.1111/exd.13377. Epub 2017 Aug 15.
118 Genetic variations within the promotor region of the human histamine H4 receptor gene in psoriasis patients.Pharmacol Res. 2016 Dec;114:121-127. doi: 10.1016/j.phrs.2016.10.003. Epub 2016 Oct 7.
119 Expression of serotonergic receptors in psoriatic skin.Arch Dermatol Res. 2006 Aug;298(3):99-106. doi: 10.1007/s00403-006-0652-6. Epub 2006 Jun 23.
120 Association between the -1438A/G polymorphism of the serotonin 2A receptor gene and late-onset psoriasis in a Thai population.Genet Mol Res. 2010 Feb 2;9(1):208-14. doi: 10.4238/vol9-1gmr718.
121 Therapeutic Elimination of the Type 1 Interferon Receptor for Treating Psoriatic Skin Inflammation.J Invest Dermatol. 2016 Oct;136(10):1990-2002. doi: 10.1016/j.jid.2016.06.608. Epub 2016 Jun 29.
122 Sequencing-based approach identified three new susceptibility loci for psoriasis.Nat Commun. 2014 Jul 9;5:4331. doi: 10.1038/ncomms5331.
123 A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.PLoS Genet. 2008 Mar 28;4(3):e1000041. doi: 10.1371/journal.pgen.1000041.
124 Up-regulation of interleukin-13 receptor alpha1 on human keratinocytes in the skin of psoriasis and atopic dermatitis.J Dermatol Sci. 2003 Oct;33(1):31-40. doi: 10.1016/s0923-1811(03)00148-8.
125 Interleukin-13 receptor in psoriatic keratinocytes: overexpression of the mRNA and underexpression of the protein.J Invest Dermatol. 2002 Nov;119(5):1114-20. doi: 10.1046/j.1523-1747.2002.19509.x.
126 Epidermal IL-15R acts as an endogenous antagonist of psoriasiform inflammation in mouse and man.J Exp Med. 2013 Sep 23;210(10):2105-17. doi: 10.1084/jem.20130291. Epub 2013 Sep 9.
127 The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man.Inflamm Res. 2019 Jun;68(6):423-426. doi: 10.1007/s00011-019-01235-x. Epub 2019 Apr 13.
128 IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease.Nat Immunol. 2019 Sep;20(9):1138-1149. doi: 10.1038/s41590-019-0467-1. Epub 2019 Aug 19.
129 The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis.Int J Mol Sci. 2019 Jul 5;20(13):3318. doi: 10.3390/ijms20133318.
130 IL-21 Induces an Imbalance of Th17/Treg Cells in Moderate-to-Severe Plaque Psoriasis Patients.Front Immunol. 2019 Aug 7;10:1865. doi: 10.3389/fimmu.2019.01865. eCollection 2019.
131 Interleukin-10 family cytokines pathway: genetic variants and psoriasis.Br J Dermatol. 2017 Jun;176(6):1577-1587. doi: 10.1111/bjd.15363. Epub 2017 Apr 21.
132 An Interleukin-25-Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin Inflammation.Immunity. 2018 Apr 17;48(4):787-798.e4. doi: 10.1016/j.immuni.2018.03.019. Epub 2018 Apr 10.
133 Role of the Pruritic Cytokine IL-31 in Autoimmune Skin Diseases.Front Immunol. 2019 Jun 21;10:1383. doi: 10.3389/fimmu.2019.01383. eCollection 2019.
134 Interleukin-32 is highly expressed in lesions of hidradenitis suppurativa.Br J Dermatol. 2017 Nov;177(5):1358-1366. doi: 10.1111/bjd.15458. Epub 2017 Sep 27.
135 Polymorphisms in IL36G gene are associated with plaque psoriasis.BMC Med Genet. 2019 Jan 11;20(1):10. doi: 10.1186/s12881-018-0742-2.
136 Multipolarity of cytokine axes in the pathogenesis of atopic dermatitis in terms of age, race, species, disease stage and biomarkers.Int Immunol. 2018 Aug 30;30(9):419-428. doi: 10.1093/intimm/dxy015.
137 Expression of B and T lymphocyte attenuator, retinoid-related orphan receptor gamma-isoform-t and interleukin 7 in psoriasis vulgaris.Australas J Dermatol. 2019 May;60(2):e132-e137. doi: 10.1111/ajd.12965. Epub 2019 Jan 22.
138 Anti-IL-12/IL-23p40 antibody ameliorates dermatitis and skin barrier dysfunction in mice with imiquimod-induced psoriasis-like dermatitis.Eur J Pharmacol. 2018 Jun 5;828:26-30. doi: 10.1016/j.ejphar.2018.03.018. Epub 2018 Mar 12.
139 JAK1/3 inhibition preserves epidermal morphology in full-thickness 3D skin models of atopic dermatitis and psoriasis.J Eur Acad Dermatol Venereol. 2019 Feb;33(2):367-375. doi: 10.1111/jdv.15301. Epub 2019 Jan 1.
140 Expression of bleomycin hydrolase in keratinization disorders.Arch Dermatol Res. 2012 Jan;304(1):31-8. doi: 10.1007/s00403-011-1180-6. Epub 2011 Oct 29.
141 Physiological and pathological roles of kallikrein-related peptidases in the epidermis.J Dermatol Sci. 2019 Aug;95(2):50-55. doi: 10.1016/j.jdermsci.2019.06.007. Epub 2019 Jun 27.
142 Aberrant human tissue kallikrein levels in the stratum corneum and serum of patients with psoriasis: dependence on phenotype, severity and therapy.Br J Dermatol. 2007 May;156(5):875-83. doi: 10.1111/j.1365-2133.2006.07743.x.
143 Lysosome Alterations in the Human Epithelial Cell Line HaCaT and Skin Specimens: Relevance to Psoriasis.Int J Mol Sci. 2019 May 7;20(9):2255. doi: 10.3390/ijms20092255.
144 Polymorphisms in HLA-related genes and psoriasis heredity in patients with psoriasis.Int J Dermatol. 2013 Aug;52(8):960-5. doi: 10.1111/ijd.12213. Epub 2013 Jul 8.
145 MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation.J Clin Invest. 2018 Jun 1;128(6):2551-2568. doi: 10.1172/JCI97426. Epub 2018 May 14.
146 Resolved psoriasis lesions retain expression of a subset of disease-related genes.J Invest Dermatol. 2011 Feb;131(2):391-400. doi: 10.1038/jid.2010.280. Epub 2010 Sep 23.
147 CARD14-Mediated Activation of Paracaspase MALT1 in Keratinocytes: Implications for Psoriasis.J Invest Dermatol. 2017 Mar;137(3):569-575. doi: 10.1016/j.jid.2016.09.031. Epub 2016 Dec 8.
148 Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2.J Immunol. 2006 Feb 1;176(3):1431-8. doi: 10.4049/jimmunol.176.3.1431.
149 Modeling clinical efficacy of the S1P receptor modulator ponesimod in psoriasis.J Dermatol Sci. 2018 Feb;89(2):136-145. doi: 10.1016/j.jdermsci.2017.11.003. Epub 2017 Nov 20.
150 Glutathione S-transferase M1 (GSTM1) genotype but not GSTT1 or MC1R genotype influences erythemal sensitivity to narrow band (TL-01) UVB phototherapy.Pharmacogenet Genomics. 2011 Apr;21(4):217-24. doi: 10.1097/FPC.0b013e32833efb36.
151 Gene expression analysis of the corticotrophin-releasing hormone-proopiomelanocortin system in psoriasis skin biopsies.Acta Derm Venereol. 2013 Jul 6;93(4):400-5. doi: 10.2340/00015555-1524.
152 Immunohistochemical staining of palisading basal cells in Bowen's disease and basal involvement in actinic keratosis: contrasting staining patterns suggest different cells of origin.Am J Dermatopathol. 2008 Apr;30(2):123-6. doi: 10.1097/DAD.0b013e3181658062.
153 Differences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic Patients.Int J Mol Sci. 2019 Nov 10;20(22):5617. doi: 10.3390/ijms20225617.
154 Kidney involvement in psoriasis: a case-control study from China.Int Urol Nephrol. 2017 Nov;49(11):1999-2003. doi: 10.1007/s11255-017-1692-x. Epub 2017 Sep 22.
155 Wnt5a exhibits layer-specific expression in adult skin, is upregulated in psoriasis, and synergizes with type 1 interferon.PLoS One. 2009;4(4):e5354. doi: 10.1371/journal.pone.0005354. Epub 2009 Apr 28.
156 Identification of a Single Nucleotide Polymorphism in NFKBIA with Different Effects on Psoriatic Arthritis and Cutaneous Psoriasis in China.Acta Derm Venereol. 2019 Jan 1;99(1):84-88. doi: 10.2340/00015555-3027.
157 Polymorphic Variations Associated With Doxorubicin-Induced Cardiotoxicity in Breast Cancer Patients.Oncol Res. 2017 Sep 21;25(8):1223-1229. doi: 10.3727/096504017X14876245096439. Epub 2017 Mar 2.
158 Mapping and identifying genes for asthma and psoriasis.Philos Trans R Soc Lond B Biol Sci. 2005 Aug 29;360(1460):1551-61. doi: 10.1098/rstb.2005.1684.
159 Modulation of cardiometabolic pathways in skin and serum from patients with psoriasis.J Transl Med. 2013 Aug 22;11:194. doi: 10.1186/1479-5876-11-194.
160 Serum neurotensin (NT) is increased in psoriasis and NT induces vascular endothelial growth factor release from human mast cells.Br J Dermatol. 2012 Jun;166(6):1349-52. doi: 10.1111/j.1365-2133.2012.10843.x. Epub 2012 May 14.
161 Association Between Soluble Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 and Coronary Artery Disease in Psoriasis.JAMA Dermatol. 2020 Feb 1;156(2):151-157. doi: 10.1001/jamadermatol.2019.3595.
162 Opioid Receptors in Psoriatic Skin: Relationship with Itch.Acta Derm Venereol. 2017 May 8;97(5):564-570. doi: 10.2340/00015555-2595.
163 The prevalence of ADH1B and OPRM1 alleles predisposing for alcohol consumption are increased in the Hungarian psoriasis population.Arch Dermatol Res. 2019 Aug;311(6):435-442. doi: 10.1007/s00403-019-01915-y. Epub 2019 Apr 22.
164 Effect of white mange mixture in a murine model of psoriasis.Exp Ther Med. 2019 Aug;18(2):881-887. doi: 10.3892/etm.2019.7641. Epub 2019 Jun 4.
165 Gene polymorphisms as predictors of response to biological therapies in psoriasis patients.Pharmacol Res. 2016 Nov;113(Pt A):71-80. doi: 10.1016/j.phrs.2016.07.020. Epub 2016 Aug 12.
166 Phosphodiesterase 4 in inflammatory diseases: Effects of apremilast in psoriatic blood and in dermal myofibroblasts through the PDE4/CD271 complex.Cell Signal. 2016 Jul;28(7):753-63. doi: 10.1016/j.cellsig.2016.01.007. Epub 2016 Jan 22.
167 Phosphodiesterase 7A: a new therapeutic target for alleviating chronic inflammation?.Curr Pharm Des. 2006;12(25):3207-20. doi: 10.2174/138161206778194123.
168 Glucose transporter-1 (GLUT-1) expression in psoriasis: correlation with disease severity.Int J Dermatol. 2018 Aug;57(8):943-951. doi: 10.1111/ijd.14037. Epub 2018 May 24.
169 Lp-PLA2 as a promising predictor of comorbidities in patients with severe psoriasis.J Dermatolog Treat. 2020 Aug;31(5):524-530. doi: 10.1080/09546634.2019.1606887. Epub 2019 May 15.
170 Suprabasal overexpression of the hsRPB7 gene in psoriatic epidermis as identified by a reverse transcriptase-polymerase chain reaction differential display model comparing psoriasis plaque tissue with peritonsillar mucosa.Am J Pathol. 2001 Feb;158(2):367-72. doi: 10.1016/s0002-9440(10)63978-8.
171 Activation of keratinocyte protein kinase C zeta in psoriasis plaques.J Invest Dermatol. 2008 Sep;128(9):2190-7. doi: 10.1038/jid.2008.81. Epub 2008 Apr 3.
172 Strong associations of psoriasis with antigen processing LMP and transport genes TAP differ by gender and phenotype.Genes Immun. 2007 Sep;8(6):513-7. doi: 10.1038/sj.gene.6364404. Epub 2007 Jun 21.
173 Associations between PTPN2 gene polymorphisms and psoriasis in Northeastern China.Gene. 2019 Jan 10;681:73-79. doi: 10.1016/j.gene.2018.09.047. Epub 2018 Sep 26.
174 The association of polymorphisms of the vitamin D receptor gene with psoriasis in the Han population of northeastern China.J Dermatol Sci. 2014 Jan;73(1):63-6. doi: 10.1016/j.jdermsci.2013.08.014. Epub 2013 Sep 7.
175 Ginsenoside compound K ameliorates imiquimod-induced psoriasis-like dermatitis through inhibiting REG3A/RegIII expression in keratinocytes.Biochem Biophys Res Commun. 2019 Aug 6;515(4):665-671. doi: 10.1016/j.bbrc.2019.06.007. Epub 2019 Jun 7.
176 Aliskiren: Preclinical evidence for the treatment of hyperproliferative skin disorders.Biomed Pharmacother. 2018 Aug;104:151-157. doi: 10.1016/j.biopha.2018.03.157. Epub 2018 May 14.
177 Multitasking Kinase RIPK1 Regulates Cell Death and Inflammation.Cold Spring Harb Perspect Biol. 2020 Mar 2;12(3):a036368. doi: 10.1101/cshperspect.a036368.
178 The E3 Ubiquitin Ligase RNF7 Negatively Regulates CARD14/CARMA2sh Signaling.Int J Mol Sci. 2017 Dec 1;18(12):2581. doi: 10.3390/ijms18122581.
179 Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-inflammatory cytokines.J Invest Dermatol. 2006 Aug;126(8):1784-91. doi: 10.1038/sj.jid.5700252. Epub 2006 Mar 16.
180 Downregulation of RUNX3 moderates the frequency of Th17 and Th22 cells in patients with psoriasis.Mol Med Rep. 2016 Jun;13(6):4606-12. doi: 10.3892/mmr.2016.5108. Epub 2016 Apr 12.
181 Psoriasis, sacro-iliitis and peripheral arthritis occurring in patients with the same HLA haplotype. A preliminary family report and a hypothetical explanation of the interaction between MHS products.Tissue Antigens. 1976 Aug;8(2):131-8.
182 Reduced stratum corneum acylceramides in autosomal recessive congenital ichthyosis with a NIPAL4 mutation.J Dermatol Sci. 2020 Jan;97(1):50-56. doi: 10.1016/j.jdermsci.2019.12.001. Epub 2019 Dec 4.
183 Study of serum levels and skin expression of S100B protein in psoriasis.An Bras Dermatol. 2017 May-Jun;92(3):323-328. doi: 10.1590/abd1806-4841.20175038.
184 Macrophage S1PR1 Signaling Alters Angiogenesis and Lymphangiogenesis During Skin Inflammation.Cells. 2019 Jul 28;8(8):785. doi: 10.3390/cells8080785.
185 Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis.PLoS One. 2017 Jul 14;12(7):e0181486. doi: 10.1371/journal.pone.0181486. eCollection 2017.
186 Chronic skin inflammation accelerates macrophage cholesterol crystal formation and atherosclerosis.JCI Insight. 2018 Jan 11;3(1):e97179. doi: 10.1172/jci.insight.97179. eCollection 2018 Jan 11.
187 Long-term treatment of chronic plaque psoriasis with biological drugs can control platelet activation: targeting the bridge between inflammation and atherothrombosis.Postepy Dermatol Alergol. 2017 Apr;34(2):131-137. doi: 10.5114/ada.2017.67077. Epub 2017 Apr 13.
188 Follow-up analysis of circulating mononuclear cell CLA expression in patients with psoriasis.J Dermatol Sci. 2005 Aug;39(2):131-3. doi: 10.1016/j.jdermsci.2005.04.005.
189 A Preliminary Study of the Effect of Semaphorin 3A and Acitretin on the Proliferation, Migration, and Apoptosis of HaCaT Cells.Indian J Dermatol. 2019 May-Jun;64(3):250. doi: 10.4103/ijd.IJD_179_18.
190 CD100-Plexin-B2 Promotes the Inflammation in Psoriasis by Activating NF-B and the Inflammasome inKeratinocytes.J Invest Dermatol. 2018 Feb;138(2):375-383. doi: 10.1016/j.jid.2017.09.005. Epub 2017 Sep 18.
191 Polymorphisms of SLCO1B1 rs4149056 and SLC22A1 rs2282143 are associated with responsiveness to acitretin in psoriasis patients.Sci Rep. 2018 Sep 4;8(1):13182. doi: 10.1038/s41598-018-31352-2.
192 Inhibiting Sphingosine Kinase 2 Derived-sphingosine-1-phosphate Ameliorates Psoriasis-like Skin Disease via Blocking Th17 Differentiation of Nave CD4 T Lymphocytes in Mice.Acta Derm Venereol. 2019 May 1;99(6):594-601. doi: 10.2340/00015555-3160.
193 Expression of pro-angiogenic genes in mesenchymal stem cells derived from dermis of patients with psoriasis.Int J Dermatol. 2016 May;55(5):e280-8. doi: 10.1111/ijd.13197. Epub 2016 Jan 8.
194 Dermal mesenchymal stem cells: a resource of migration-associated function in psoriasis?.Stem Cell Res Ther. 2019 Feb 13;10(1):54. doi: 10.1186/s13287-019-1159-3.
195 CARD14/CARMA2sh and TANK differentially regulate poly(I:C)-induced inflammatory reaction in keratinocytes.J Cell Physiol. 2020 Mar;235(3):1895-1902. doi: 10.1002/jcp.29161. Epub 2019 Sep 4.
196 Xenotransplantation Model of Psoriasis.Methods Mol Biol. 2017;1559:83-90. doi: 10.1007/978-1-4939-6786-5_7.
197 Evaluation of plasma levels of tissue factor and tissue factor pathway inhibitor in patients with psoriasis.Postepy Dermatol Alergol. 2019 Aug;36(4):442-448. doi: 10.5114/ada.2019.87447. Epub 2019 Aug 30.
198 Activation of ribosomal protein S6 kinase in psoriatic lesions and cultured human keratinocytes by epidermal growth factor receptor ligands.J Invest Dermatol. 1997 Jan;108(1):98-102. doi: 10.1111/1523-1747.ep12285647.
199 Keratinocyte transglutaminase expression varies in squamous cell carcinomas.J Invest Dermatol. 1994 Apr;102(4):462-9. doi: 10.1111/1523-1747.ep12373021.
200 The polymorphism rs4696480 in the TLR2 gene is associated with psoriasis patients in the Turkish population.Immunol Lett. 2019 Jul;211:28-32. doi: 10.1016/j.imlet.2019.05.008. Epub 2019 May 21.
201 Activation of the HMGB1TLR4NFB pathway may occur in patients with atopic eczema.Mol Med Rep. 2017 Sep;16(3):2714-2720. doi: 10.3892/mmr.2017.6942. Epub 2017 Jul 6.
202 Staphylococcal -toxin induces a functional upregulation of TLR-2 on human peripheral blood monocytes.Exp Dermatol. 2015 May;24(5):381-3. doi: 10.1111/exd.12674.
203 Acetyl-11-keto--boswellic acid inhibits the secretion of cytokines by dendritic cells via the TLR7/8 pathway in an imiquimod-induced psoriasis mouse model and in vitro.Life Sci. 2018 Aug 15;207:90-104. doi: 10.1016/j.lfs.2018.05.044. Epub 2018 May 31.
204 Toll-like receptor 9 promoter polymorphism as a predictive factor of narrow-band UVB phototherapy response in patients with psoriasis.Photodermatol Photoimmunol Photomed. 2015 Mar;31(2):98-103. doi: 10.1111/phpp.12160. Epub 2015 Jan 19.
205 B-cell maturation antigen (BCMA) activation exerts specific proinflammatory effects in normal human keratinocytes and is preferentially expressed in inflammatory skin pathologies.Endocrinology. 2012 Feb;153(2):739-49. doi: 10.1210/en.2011-1504. Epub 2011 Dec 13.
206 Differential expression of BAFF and its receptors in discoid lupus erythematosus patients.J Dermatol Sci. 2014 Mar;73(3):216-24. doi: 10.1016/j.jdermsci.2013.11.007. Epub 2013 Nov 16.
207 TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis.Nat Commun. 2017 May 22;8:15395. doi: 10.1038/ncomms15395.
208 Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling.Hum Mol Genet. 2017 Nov 1;26(21):4301-4313. doi: 10.1093/hmg/ddx328.
209 TRIM27 promotes IL-6-induced proliferation and inflammation factor production by activating STAT3 signaling in HaCaT cells.Am J Physiol Cell Physiol. 2020 Feb 1;318(2):C272-C281. doi: 10.1152/ajpcell.00314.2019. Epub 2019 Nov 20.
210 TRPA1 Acts in a Protective Manner in Imiquimod-Induced Psoriasiform Dermatitis in Mice.J Invest Dermatol. 2018 Aug;138(8):1774-1784. doi: 10.1016/j.jid.2018.02.040. Epub 2018 Mar 14.
211 Hypoxia inhibits TNF--induced TSLP expression in keratinocytes.PLoS One. 2019 Nov 4;14(11):e0224705. doi: 10.1371/journal.pone.0224705. eCollection 2019.
212 ITK and RLK Inhibitor PRN694 Improves Skin Disease in Two Mouse Models of Psoriasis.J Invest Dermatol. 2018 Apr;138(4):864-871. doi: 10.1016/j.jid.2017.10.029. Epub 2017 Nov 10.
213 Selective Tyk2 inhibitors as potential therapeutic agents: a patent review (2015-2018).Expert Opin Ther Pat. 2019 Feb;29(2):137-149. doi: 10.1080/13543776.2019.1567713. Epub 2019 Jan 22.
214 Ubiquitin-specific peptidase 2 as a potential link between microRNA-125b and psoriasis.Br J Dermatol. 2017 Mar;176(3):723-731. doi: 10.1111/bjd.14916. Epub 2016 Dec 30.
215 Efficacy and Safety of Intravenous Golimumab Through One Year in Patients With Active Psoriatic Arthritis.Arthritis Care Res (Hoboken). 2020 Jun;72(6):806-813. doi: 10.1002/acr.23905. Epub 2020 May 15.
216 Discovery and process development of a novel TACE inhibitor for the topical treatment of psoriasis.Bioorg Med Chem. 2018 Feb 15;26(4):945-956. doi: 10.1016/j.bmc.2017.07.054. Epub 2017 Aug 2.
217 In-depth serum proteomics reveals biomarkers of psoriasis severity and response to traditional Chinese medicine.Theranostics. 2019 Apr 13;9(9):2475-2488. doi: 10.7150/thno.31144. eCollection 2019.
218 Mannan-binding lectin promotes keratinocyte to produce CXCL1 and enhances neutrophil infiltration at the early stages of psoriasis.Exp Dermatol. 2019 Sep;28(9):1017-1024. doi: 10.1111/exd.13995. Epub 2019 Aug 13.
219 FCGR3A-V158F polymorphism is a disease-specific pharmacogenetic marker for the treatment of psoriasis with Fc-containing TNF inhibitors.Pharmacogenomics J. 2017 Jun;17(3):237-241. doi: 10.1038/tpj.2016.16. Epub 2016 Apr 5.
220 FGF-7 facilitates the process of psoriasis by inducing TNF- expression in HaCaT cells.Acta Biochim Biophys Sin (Shanghai). 2019 Sep 6;51(10):1056-1063. doi: 10.1093/abbs/gmz095.
221 AP-1 Expression and its Clinical Relevance in Immune Disorders and Cancer.Am J Med Sci. 2017 May;353(5):474-483. doi: 10.1016/j.amjms.2017.01.019. Epub 2017 Feb 1.
222 Identification of unique proteomic signatures in allergic and non-allergic skin disease.Clin Exp Allergy. 2017 Nov;47(11):1456-1467. doi: 10.1111/cea.12979. Epub 2017 Aug 11.
223 Integrative analyses reveal biological pathways and key genes in psoriasis.Br J Dermatol. 2017 Nov;177(5):1349-1357. doi: 10.1111/bjd.15682. Epub 2017 Oct 25.
224 TNF-alpha inhibition could reduce biomarkers of endothelial dysfunction in patients with moderate to severe psoriasis: A 52-week echo-Doppler based quasi-experimental study.Med Clin (Barc). 2018 Jun 22;150(12):465-468. doi: 10.1016/j.medcli.2017.08.014. Epub 2017 Oct 28.
225 Squamous Cell Carcinoma Antigen 2 (SCCA2, SERPINB4): An Emerging Biomarker for Skin Inflammatory Diseases.Int J Mol Sci. 2018 Apr 6;19(4):1102. doi: 10.3390/ijms19041102.
226 The TNFRSF1B rs1061622 polymorphism (p.M196R) is associated with biological drug outcome in Psoriasis patients.Arch Dermatol Res. 2015 Jul;307(5):405-12. doi: 10.1007/s00403-014-1533-z. Epub 2014 Dec 24.
227 Differential effects of Wnt5a on the proliferation, differentiation and inflammatory response of keratinocytes.Mol Med Rep. 2018 Mar;17(3):4043-4048. doi: 10.3892/mmr.2017.8358. Epub 2017 Dec 27.
228 Systematic linkage disequilibrium analysis of SLC12A8 at PSORS5 confirms a role in susceptibility to psoriasis vulgaris.J Invest Dermatol. 2005 Nov;125(5):906-12. doi: 10.1111/j.0022-202X.2005.23847.x.
229 Proteomics of skin proteins in psoriasis: from discovery and verification in a mouse model to confirmation in humans.Mol Cell Proteomics. 2015 Jan;14(1):109-19. doi: 10.1074/mcp.M114.042242. Epub 2014 Oct 28.
230 Major Role for TRPV1 and InsP3R inPAR2-Elicited Inflammatory MediatorProduction in Differentiated Human Keratinocytes.J Invest Dermatol. 2018 Jul;138(7):1564-1572. doi: 10.1016/j.jid.2018.01.034. Epub 2018 Feb 17.
231 Investigation of the chromosome 17q25 PSORS2 locus in atopic dermatitis.J Invest Dermatol. 2006 Mar;126(3):603-6. doi: 10.1038/sj.jid.5700108.
232 Polymorphism of glutathione S-transferase M1 and T1 genes and susceptibility to psoriasis disease: A study from North India.Indian J Dermatol Venereol Leprol. 2018 Jan-Feb;84(1):39-44. doi: 10.4103/ijdvl.IJDVL_1128_16.
233 Matrix metalloproteinase-2 promoter variability in psoriasis.Arch Dermatol Res. 2009 Jul;301(6):467-73. doi: 10.1007/s00403-009-0947-5. Epub 2009 Apr 10.
234 Combined Transcriptomic Analysis Revealed AKR1B10 Played an Important Role in Psoriasis through the Dysregulated Lipid Pathway and Overproliferation of Keratinocyte.Biomed Res Int. 2017;2017:8717369. doi: 10.1155/2017/8717369. Epub 2017 Oct 24.
235 Mast cells express CYP27A1 and CYP27B1 in epithelial skin cancers and psoriasis.Eur J Dermatol. 2015 Nov-Dec;25(6):548-55. doi: 10.1684/ejd.2015.2645.
236 Cutaneous expression of cytochrome P450 CYP2S1: individuality in regulation by therapeutic agents for psoriasis and other skin diseases. Lancet. 2003 Apr 19;361(9366):1336-43.
237 Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease.JAMA Neurol. 2016 Jun 1;73(6):691-7. doi: 10.1001/jamaneurol.2016.0150.
238 The role of sterol-C4-methyl oxidase in epidermal biology.Biochim Biophys Acta. 2014 Mar;1841(3):331-5. doi: 10.1016/j.bbalip.2013.10.009. Epub 2013 Oct 18.
239 A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis.Nat Genet. 2003 Dec;35(4):349-56. doi: 10.1038/ng1268. Epub 2003 Nov 9.
240 A Controlled Study of the Feasibility and Efficacy of a Cloud-Based Interactive Management Program Between Patients with Psoriasis and Physicians.Med Sci Monit. 2019 Feb 4;25:970-976. doi: 10.12659/MSM.913304.
241 Influence of calcium on the proteolytic degradation of the calmodulin-like skin protein (calmodulin-like protein 5) in psoriatic epidermis.Exp Dermatol. 2006 Jun;15(6):469-77. doi: 10.1111/j.1600-0625.2006.00433.x.
242 An association study of 22 candidate genes in psoriasis families reveals shared genetic factors with other autoimmune and skin disorders.J Invest Dermatol. 2009 Nov;129(11):2637-45. doi: 10.1038/jid.2009.157. Epub 2009 Jun 25.
243 Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci.Nat Commun. 2015 May 5;6:7001. doi: 10.1038/ncomms8001.
244 Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.Nat Commun. 2015 Apr 23;6:6916. doi: 10.1038/ncomms7916.
245 Genome-wide association study of psoriasis in an Egyptian population.Exp Dermatol. 2019 May;28(5):623-627. doi: 10.1111/exd.13926.
246 Decreased A-to-I RNA editing as a source of keratinocytes' dsRNA in psoriasis.RNA. 2018 Jun;24(6):828-840. doi: 10.1261/rna.064659.117. Epub 2018 Mar 28.
247 A potential association between psoriasin to rs4819554 of IL-17RA gene polymorphism in psoriasis Egyptian patients.Arch Dermatol Res. 2020 May;312(4):273-281. doi: 10.1007/s00403-019-02011-x. Epub 2019 Nov 19.
248 Relationship between human leukocyte antigen DRB1 and psoriasis in Iraqi patients.Saudi Med J. 2018 Sep;39(9):886-890. doi: 10.15537/smj.2018.9.23156.
249 Regulation of RANKL-induced osteoclastogenesis by RING finger protein RNF114.J Orthop Res. 2018 Jan;36(1):159-166. doi: 10.1002/jor.23654. Epub 2017 Jul 31.
250 A promoter sequence variant of ZNF750 is linked with familial psoriasis.J Invest Dermatol. 2008 Jul;128(7):1662-8. doi: 10.1038/jid.2008.1. Epub 2008 Feb 7.
251 Chronic hand eczema: is IL-36 helpful in diagnosis and classification?.G Ital Dermatol Venereol. 2017 Dec;152(6):578-585. doi: 10.23736/S0392-0488.16.05312-8. Epub 2016 Apr 1.
252 MicroRNA-146 and cell trauma down-regulate expression of the psoriasis-associated atypical chemokine receptor ACKR2.J Biol Chem. 2018 Feb 23;293(8):3003-3012. doi: 10.1074/jbc.M117.809780. Epub 2017 Dec 26.
253 Upper keratinocytes of psoriatic skin lesions express high levels of NAP-1/IL-8 mRNA in situ.J Invest Dermatol. 1991 Jul;97(1):73-9. doi: 10.1111/1523-1747.ep12478128.
254 EFLA 945 restricts AIM2 inflammasome activation by preventing DNA entry for psoriasis treatment.Cytokine. 2020 Mar;127:154951. doi: 10.1016/j.cyto.2019.154951. Epub 2019 Dec 11.
255 Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis.Sci Rep. 2016 Oct 4;6:34690. doi: 10.1038/srep34690.
256 Urinary orosomucoid: a new marker of cardiovascular risk in psoriatic patients?.Ther Clin Risk Manag. 2019 Jul 5;15:831-837. doi: 10.2147/TCRM.S197633. eCollection 2019.
257 Abnormality of RUNX1 signal transduction in psoriatic CD34+ bone marrow cells.Br J Dermatol. 2011 May;164(5):1043-51. doi: 10.1111/j.1365-2133.2010.10192.x.
258 Proteomic plasma profile of psoriatic patients.J Pharm Biomed Anal. 2018 Jun 5;155:185-193. doi: 10.1016/j.jpba.2018.03.068. Epub 2018 Apr 4.
259 BCAP 31 expression and promoter demethylation in psoriasis.Asian Pac J Allergy Immunol. 2017 Jun;35(2):86-90. doi: 10.12932/AP0818.
260 Bcl-3 induced by IL-22 via STAT3 activation acts as a potentiator of psoriasis-related gene expression in epidermal keratinocytes.Eur J Immunol. 2018 Jan;48(1):168-179. doi: 10.1002/eji.201747017. Epub 2017 Nov 20.
261 Correlation analysis of the HLA-DPB1*05:01 and BTNL2 genes within the histocompatibility complex region with a clinical phenotype of psoriasis vulgaris in the Chinese Han population.J Gene Med. 2017 Sep;19(9-10). doi: 10.1002/jgm.2961. Epub 2017 Sep 19.
262 Increased TrCP are associated with imiquimod-induced psoriasis-like skin inflammation in mice via NF-B signaling pathway.Gene. 2016 Oct 30;592(1):164-171. doi: 10.1016/j.gene.2016.07.066. Epub 2016 Jul 28.
263 A novel splicing variant of CADM2 as a protective transcript of psoriasis.Biochem Biophys Res Commun. 2011 Sep 9;412(4):626-32. doi: 10.1016/j.bbrc.2011.08.013. Epub 2011 Aug 11.
264 RETRACTED: NFKB1 mediates Th1/Th17 activation in the pathogenesis of psoriasis.Cell Immunol. 2018 Sep;331:16-21. doi: 10.1016/j.cellimm.2018.04.016. Epub 2018 May 2.
265 Inhibition of CCR7/CCL19 axis in lesional skin is a critical event for clinical remission induced by TNF blockade in patients with psoriasis.Am J Pathol. 2013 Aug;183(2):413-21. doi: 10.1016/j.ajpath.2013.04.021. Epub 2013 May 31.
266 CCL7 contributes to the TNF-alpha-dependent inflammation of lesional psoriatic skin.Exp Dermatol. 2015 Jul;24(7):522-8. doi: 10.1111/exd.12709. Epub 2015 May 4.
267 c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies.Nat Immunol. 2019 Aug;20(8):992-1003. doi: 10.1038/s41590-019-0423-0. Epub 2019 Jul 1.
268 A molecular basis of human T cell receptor autoreactivity toward self-phospholipids.Sci Immunol. 2017 Oct 20;2(16):eaao1384. doi: 10.1126/sciimmunol.aao1384.
269 A central role for transcription factor C/EBP-beta in regulating CD1d gene expression in human keratinocytes.J Immunol. 2009 Aug 1;183(3):1657-66. doi: 10.4049/jimmunol.0900057. Epub 2009 Jul 10.
270 Comparison of NAPSI and N-NAIL for evaluation of fingernail psoriasis in patients with moderate-to-severe plaque psoriasis treated using ustekinumab.J Dermatolog Treat. 2019 Mar;30(2):123-128. doi: 10.1080/09546634.2018.1476649. Epub 2018 May 25.
271 Polymorphisms in CD84, IL12B and TNFAIP3 are associated with response to biologics in patients with psoriasis. Br J Dermatol. 2017 May;176(5):1288-1296.
272 Psoriasis and Pro-angiogenetic Factor CD93: Gene Expression and Association with Gene Polymorphism Suggests a Role in Disease Pathogenesis.Acta Derm Venereol. 2017 Aug 31;97(8):916-921. doi: 10.2340/00015555-2682.
273 Berberine downregulates CDC6 and inhibits proliferation via targeting JAK-STAT3 signaling in keratinocytes.Cell Death Dis. 2019 Mar 20;10(4):274. doi: 10.1038/s41419-019-1510-8.
274 Shikonin induces apoptosis and suppresses growth in keratinocytes via CEBP- upregulation.Int Immunopharmacol. 2019 Jul;72:511-521. doi: 10.1016/j.intimp.2019.04.047. Epub 2019 May 7.
275 Human S100A15 splice variants are differentially expressed in inflammatory skin diseases and regulated through Th1 cytokines and calcium.Exp Dermatol. 2007 Aug;16(8):685-91. doi: 10.1111/j.1600-0625.2007.00587.x.
276 C19, a C-terminal peptide of CKLF1, decreases inflammation and proliferation of dermal capillaries in psoriasis.Sci Rep. 2017 Oct 24;7(1):13890. doi: 10.1038/s41598-017-13799-x.
277 Role of nitric oxide-scavenging activity of Karanjin and Pongapin in the treatment of Psoriasis.3 Biotech. 2018 Aug;8(8):338. doi: 10.1007/s13205-018-1337-5. Epub 2018 Jul 25.
278 Claudin-3 - a new intestinal integrity marker in patients with psoriasis: association with disease severity.J Eur Acad Dermatol Venereol. 2019 Oct;33(10):1907-1912. doi: 10.1111/jdv.15700. Epub 2019 Jun 19.
279 A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis.J Invest Dermatol. 2010 Nov;130(11):2611-20. doi: 10.1038/jid.2010.196. Epub 2010 Jul 15.
280 Treatment modifying factors of biologics for psoriatic arthritis: a systematic review and Bayesian meta-regression.Clin Exp Rheumatol. 2017 Jul-Aug;35(4):681-688. Epub 2017 Jan 15.
281 Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression.Hum Genet. 2016 May;135(5):485-497. doi: 10.1007/s00439-016-1654-x. Epub 2016 Mar 18.
282 Dermatology Life Quality Index and disease coping strategies in psoriasis patients.Postepy Dermatol Alergol. 2019 Aug;36(4):419-424. doi: 10.5114/ada.2018.75810. Epub 2019 Aug 30.
283 Evaluation of the atherogenic tendency of lipids and lipoprotein content and their relationships with oxidant-antioxidant system in patients with psoriasis.Clin Chim Acta. 2003 Feb;328(1-2):71-82. doi: 10.1016/s0009-8981(02)00373-x.
284 Functional Genomics and Its Bench-to-Bedside Translation Pertaining to the Identified Susceptibility Alleles and Loci in Ankylosing Spondylitis.Curr Rheumatol Rep. 2016 Oct;18(10):63. doi: 10.1007/s11926-016-0612-x.
285 Overexpression of cellular retinoic acid-binding protein type II (CRABP-II) and down-regulation of CRABP-I in psoriatic skin.Dermatology. 1992;185(4):251-6. doi: 10.1159/000247462.
286 Cornulin Is Induced in Psoriasis Lesions and Promotes Keratinocyte Proliferation via Phosphoinositide 3-Kinase/Akt Pathways.J Invest Dermatol. 2019 Jan;139(1):71-80. doi: 10.1016/j.jid.2018.06.184. Epub 2018 Sep 25.
287 Towards the development of a RNAi-based topical treatment for psoriasis: Proof-of-concept in a 3D psoriasis skin model.Exp Dermatol. 2018 May;27(5):463-469. doi: 10.1111/exd.13414. Epub 2017 Nov 2.
288 Overexpression of Drosha, DiGeorge syndrome critical region gene 8 (DGCR8), and Dicer mRNAs in the pathogenesis of psoriasis.J Cosmet Dermatol. 2017 Dec;16(4):e48-e53. doi: 10.1111/jocd.12336. Epub 2017 Mar 25.
289 The epigenetic mechanism for discordance of autoimmunity in monozygotic twins.J Autoimmun. 2017 Sep;83:43-50. doi: 10.1016/j.jaut.2017.04.003. Epub 2017 Apr 12.
290 Homeostatic Function of Dermokine in the Skin Barrier and Inflammation.J Invest Dermatol. 2020 Apr;140(4):838-849.e9. doi: 10.1016/j.jid.2019.09.011. Epub 2019 Oct 25.
291 Does imiquimod pretreatment optimize 308-nm excimer laser (UVB) therapy in psoriasis patients?.Photodermatol Photoimmunol Photomed. 2017 Jul;33(4):193-202. doi: 10.1111/phpp.12299. Epub 2017 Apr 20.
292 Tnfa signaling through tnfr2 protects skin against oxidative stress-induced inflammation.PLoS Biol. 2014 May 6;12(5):e1001855. doi: 10.1371/journal.pbio.1001855. eCollection 2014 May.
293 Overexpression of the oncofetal Fn variant containing the EDA splice-in segment in the dermal-epidermal junction of psoriatic uninvolved skin.J Invest Dermatol. 2000 Apr;114(4):706-11. doi: 10.1046/j.1523-1747.2000.00871.x.
294 Levels of miR-31 and its target genes in dermal mesenchymal cells of patients with psoriasis.Int J Dermatol. 2019 Feb;58(2):198-204. doi: 10.1111/ijd.14197. Epub 2018 Sep 9.
295 Guselkumab for the treatment of adults with moderate to severe plaque psoriasis.Expert Rev Clin Immunol. 2019 Jun;15(6):589-597. doi: 10.1080/1744666X.2019.1601014. Epub 2019 Apr 12.
296 Five regulatory genes detected by matching signatures of eQTL and GWAS in psoriasis.J Dermatol Sci. 2014 Nov;76(2):139-42. doi: 10.1016/j.jdermsci.2014.07.007. Epub 2014 Aug 13.
297 Dimethyl fumarate (DMF) vs. monoethyl fumarate (MEF) salts for the treatment of plaque psoriasis: a review of clinical data.Arch Dermatol Res. 2018 Aug;310(6):475-483. doi: 10.1007/s00403-018-1825-9. Epub 2018 Mar 24.
298 Chronic Psoriatic Skin Inflammation Leads to Increased Monocyte Adhesion and Aggregation.J Immunol. 2015 Sep 1;195(5):2006-18. doi: 10.4049/jimmunol.1402307. Epub 2015 Jul 29.
299 Genotypic variability-based genome-wide association study identifies non-additive loci HLA-C and IL12B for psoriasis.J Hum Genet. 2018 Mar;63(3):289-296. doi: 10.1038/s10038-017-0350-6. Epub 2017 Dec 19.
300 Genetic Study on Small Insertions and Deletions in Psoriasis Reveals a Role in Complex Human Diseases.J Invest Dermatol. 2019 Nov;139(11):2302-2312.e14. doi: 10.1016/j.jid.2019.03.1157. Epub 2019 May 10.
301 Wnt/-Catenin and Wnt5a/Ca Pathways Regulate Proliferation and Apoptosis of Keratinocytes in Psoriasis Lesions.Cell Physiol Biochem. 2015;36(5):1890-902. doi: 10.1159/000430158. Epub 2015 Jul 17.
302 MiR-99a inhibits keratinocyte proliferation by targeting Frizzled-5 (FZD5) / FZD8 through -catenin signaling in psoriasis.Pharmazie. 2017 Aug 1;72(8):461-467. doi: 10.1691/ph.2017.7018.
303 Lack of Galanin Receptor 3 Alleviates Psoriasis by Altering Vascularization, Immune Cell Infiltration, and CytokineExpression.J Invest Dermatol. 2018 Jan;138(1):199-207. doi: 10.1016/j.jid.2017.08.015. Epub 2017 Aug 24.
304 Regulatory role for Krppel-like zinc-finger protein Gli-similar 1 (Glis1) in PMA-treated and psoriatic epidermis.J Invest Dermatol. 2006 Jan;126(1):49-60. doi: 10.1038/sj.jid.5700018.
305 Systemic and Local Increase of Granulysin Expression in Cytotoxic Lymphocytes in Severe Psoriasis.Acta Derm Venereol. 2019 Nov 1;99(12):1136-1142. doi: 10.2340/00015555-3298.
306 GPR15 is not critically involved in the regulation of murine psoriasiform dermatitis.J Dermatol Sci. 2019 Apr;94(1):196-204. doi: 10.1016/j.jdermsci.2019.01.008. Epub 2019 Mar 12.
307 Tazarotene-induced gene 1 (TIG1), a novel retinoic acid receptor-responsive gene in skin.J Invest Dermatol. 1996 Feb;106(2):269-74. doi: 10.1111/1523-1747.ep12340668.
308 The Grainyhead transcription factor Grhl3/Get1 suppresses miR-21 expression and tumorigenesis in skin: modulation of the miR-21 target MSH2 by RNA-binding protein DND1.Oncogene. 2013 Mar 21;32(12):1497-507. doi: 10.1038/onc.2012.168. Epub 2012 May 21.
309 Association between genetic polymorphisms of glutathione S-transferase M1/T1 and psoriasis in a population from the area of the strict of messina (Southern Italy).Free Radic Res. 2020 Jan;54(1):57-63. doi: 10.1080/10715762.2019.1698738. Epub 2019 Dec 10.
310 Granzyme A potentiates chemokine production in IL-17-stimulated keratinocytes.Exp Dermatol. 2017 Sep;26(9):824-827. doi: 10.1111/exd.13284. Epub 2017 Apr 10.
311 Efficacy and safety of HAT1 compared with calcipotriol in the treatment of patients with mild to moderate chronic plaque psoriasis: results from an open-label randomized comparative pilot clinical study.Clin Exp Dermatol. 2020 Apr;45(3):318-322. doi: 10.1111/ced.14074. Epub 2019 Sep 26.
312 Genome-wide DNA methylation analysis in ankylosing spondylitis identifies HLA-B*27 dependent and independent DNA methylation changes in whole blood.J Autoimmun. 2019 Aug;102:126-132. doi: 10.1016/j.jaut.2019.04.022. Epub 2019 May 23.
313 Association of TAP and HLA-DM genes with psoriasis in Koreans.J Invest Dermatol. 2003 Apr;120(4):616-22. doi: 10.1046/j.1523-1747.2003.12091.x.
314 Lack of association between cytotoxic T-lymphocyte antigen-4+49A/G polymorphism and psoriasis and vitiligo: A meta-analysis of case-control studies.Gene. 2015 Sep 1;568(2):196-202. doi: 10.1016/j.gene.2015.05.051. Epub 2015 May 24.
315 Psoriasis regression analysis of MHC loci identifies shared genetic variants with vitiligo.PLoS One. 2011;6(11):e23089. doi: 10.1371/journal.pone.0023089. Epub 2011 Nov 18.
316 Deletion of the activating NKG2C receptor and a functional polymorphism in its ligand HLA-E in psoriasis susceptibility.Exp Dermatol. 2013 Oct;22(10):679-81. doi: 10.1111/exd.12233.
317 Effect of alterations in apoptotic pathway on development of metabolic syndrome in patients with psoriasis vulgaris.Br J Dermatol. 2017 Jun;176(6):1549-1557. doi: 10.1111/bjd.15185. Epub 2017 Apr 10.
318 Proinflammatory and anti-inflammatory cytokine profiles in psoriasis: use as laboratory biomarkers and disease predictors.Inflamm Res. 2019 Jul;68(7):557-567. doi: 10.1007/s00011-019-01238-8. Epub 2019 May 6.
319 Parakeratosis in skin is associated with loss of inhibitor of differentiation 4 via promoter methylation.Hum Pathol. 2011 Dec;42(12):1878-87. doi: 10.1016/j.humpath.2011.02.005. Epub 2011 Jun 12.
320 Serum IFI16 and anti-IFI16 antibodies in psoriatic arthritis.Clin Exp Immunol. 2020 Jan;199(1):88-96. doi: 10.1111/cei.13376. Epub 2019 Oct 15.
321 Pso p27, a SERPINB3/B4-derived protein, is most likely a common autoantigen in chronic inflammatory diseases.Clin Immunol. 2017 Jan;174:10-17. doi: 10.1016/j.clim.2016.11.006. Epub 2016 Nov 15.
322 The anti-apoptotic protein G1P3 is overexpressed in psoriasis and regulated by the non-coding RNA, PRINS.Exp Dermatol. 2010 Mar;19(3):269-78. doi: 10.1111/j.1600-0625.2010.01066.x.
323 IL28RA inhibits human epidermal keratinocyte proliferation by inhibiting cell cycle progression.Mol Biol Rep. 2019 Feb;46(1):1189-1197. doi: 10.1007/s11033-019-04586-0. Epub 2019 Jan 10.
324 Gene-gene interactions in IL23/Th17 pathway contribute to psoriasis susceptibility in Chinese Han population.J Eur Acad Dermatol Venereol. 2013 Sep;27(9):1156-62. doi: 10.1111/j.1468-3083.2012.04683.x. Epub 2012 Aug 22.
325 IL-17C amplifies epithelial inflammation in human psoriasis and atopic eczema.J Eur Acad Dermatol Venereol. 2020 Apr;34(4):800-809. doi: 10.1111/jdv.16126. Epub 2020 Jan 19.
326 Ultraviolet B Inhibits IL-17A/TNF--Stimulated Activation of Human Dermal Fibroblasts by Decreasing the Expression of IL-17RA and IL-17RC on Fibroblasts.Front Immunol. 2017 Feb 3;8:91. doi: 10.3389/fimmu.2017.00091. eCollection 2017.
327 Interleukin-17 receptor D constitutes an alternative receptor for interleukin-17A important in psoriasis-like skin inflammation.Sci Immunol. 2019 Jun 7;4(36):eaau9657. doi: 10.1126/sciimmunol.aau9657.
328 IL-36, IL-37, and IL-38 Cytokines in Skin and Joint Inflammation: A Comprehensive Review of Their Therapeutic Potential.Int J Mol Sci. 2019 Mar 13;20(6):1257. doi: 10.3390/ijms20061257.
329 Association analysis of IL20RA and IL20RB genes in psoriasis.Genes Immun. 2008 Jul;9(5):445-51. doi: 10.1038/gene.2008.36. Epub 2008 May 15.
330 Ultrasound targeting of Q-starch/miR-197 complexes for topical treatment of psoriasis.J Control Release. 2018 Aug 28;284:103-111. doi: 10.1016/j.jconrel.2018.05.040. Epub 2018 Jun 2.
331 Regulation of IL-22BP in psoriasis.Sci Rep. 2018 Mar 23;8(1):5085. doi: 10.1038/s41598-018-23510-3.
332 Characterization of novel anti-IL-26 neutralizing monoclonal antibodies for the treatment of inflammatory diseases including psoriasis.MAbs. 2019 Nov-Dec;11(8):1428-1442. doi: 10.1080/19420862.2019.1654305. Epub 2019 Aug 18.
333 Immune Control by TRAF6-Mediated Pathways of Epithelial Cells in the EIME (Epithelial Immune Microenvironment).Front Immunol. 2019 May 16;10:1107. doi: 10.3389/fimmu.2019.01107. eCollection 2019.
334 Involvement of IL-9 in Th17-associated inflammation and angiogenesis of psoriasis.PLoS One. 2013;8(1):e51752. doi: 10.1371/journal.pone.0051752. Epub 2013 Jan 15.
335 Variation at the IRF2 gene and susceptibility to psoriasis in chromosome 4q-linked families.J Invest Dermatol. 2004 Mar;122(3):640-3. doi: 10.1046/j.0022-202X.2004.22135.x.
336 Reduced CD18 levels drive regulatory T cell conversion into Th17 cells in the CD18hypo PL/J mouse model of psoriasis.J Immunol. 2013 Mar 15;190(6):2544-53. doi: 10.4049/jimmunol.1202399. Epub 2013 Feb 15.
337 The (CCTTT) n pentanucleotide repeat polymorphism in the inducible nitric oxide synthase gene promoter and the risk of psoriasis in Taiwanese.Arch Dermatol Res. 2015 Jul;307(5):425-32. doi: 10.1007/s00403-015-1542-6. Epub 2015 Feb 8.
338 Accumulation of FLT3(+) CD11c (+) dendritic cells in psoriatic lesions and the anti-psoriatic effect of a selective FLT3 inhibitor.Immunol Res. 2014 Oct;60(1):112-26. doi: 10.1007/s12026-014-8521-4.
339 Omentin serum levels and omentin gene Val109Asp polymorphism in patients with psoriasis.Int J Dermatol. 2014 May;53(5):601-5. doi: 10.1111/ijd.12306. Epub 2013 Dec 10.
340 Downregulation of involucrin in psoriatic lesions following therapy with propylthiouracil, an anti-thyroid thioureylene: immunohistochemistry and gene expression analysis.Int J Dermatol. 2015 Mar;54(3):302-6. doi: 10.1111/ijd.12565. Epub 2014 Sep 30.
341 Human leukocyte antigen (HLA)-C polymorphisms are associated with a decreased risk of rheumatoid arthritis.Mol Biol Rep. 2014 Jun;41(6):4103-8. doi: 10.1007/s11033-014-3280-9. Epub 2014 Feb 25.
342 Identification of PTPN22, ST6GAL1 and JAZF1 as psoriasis risk genes demonstrates shared pathogenesis between psoriasis and diabetes.Exp Dermatol. 2017 Nov;26(11):1112-1117. doi: 10.1111/exd.13393. Epub 2017 Aug 25.
343 Genetic polymorphisms of killer cell immunoglobulin-like receptors are associated with susceptibility to psoriasis vulgaris.J Invest Dermatol. 2004 May;122(5):1133-6. doi: 10.1111/j.0022-202X.2004.22517.x.
344 Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease.PLoS Genet. 2012 Feb;8(2):e1002514. doi: 10.1371/journal.pgen.1002514. Epub 2012 Feb 16.
345 MiR-744-3p regulates keratinocyte proliferation and differentiation via targeting KLLN in psoriasis.Exp Dermatol. 2019 Mar;28(3):283-291. doi: 10.1111/exd.13888.
346 IL-17 and IL-22 Promote Keratinocyte Stemness in the Germinative Compartment in Psoriasis.J Invest Dermatol. 2019 Jul;139(7):1564-1573.e8. doi: 10.1016/j.jid.2019.01.014. Epub 2019 Jan 23.
347 IL-37 ameliorates the inflammatory process in psoriasis by suppressing proinflammatory cytokine production.J Immunol. 2014 Feb 15;192(4):1815-23. doi: 10.4049/jimmunol.1300047. Epub 2014 Jan 22.
348 Pushing the Envelope in Psoriasis: Late Cornified Envelope Proteins Possess Antimicrobial Activity.J Invest Dermatol. 2017 Nov;137(11):2257-2259. doi: 10.1016/j.jid.2017.08.026.
349 A large-scale screen for coding variants predisposing to psoriasis.Nat Genet. 2014 Jan;46(1):45-50. doi: 10.1038/ng.2827. Epub 2013 Nov 10.
350 LMO4 Is a Disease-Provocative Transcription Coregulator Activated by IL-23 in Psoriatic Keratinocytes.J Invest Dermatol. 2018 May;138(5):1078-1087. doi: 10.1016/j.jid.2017.12.010. Epub 2017 Dec 16.
351 Fumaric acid esters for psoriasis: a systematic review.Ir J Med Sci. 2017 Feb;186(1):161-177. doi: 10.1007/s11845-016-1470-2. Epub 2016 Jun 7.
352 SLURP-2, a novel member of the human Ly-6 superfamily that is up-regulated in psoriasis vulgaris.Genomics. 2003 Jan;81(1):26-33. doi: 10.1016/s0888-7543(02)00025-3.
353 Genome-Wide Pathway Analysis Identifies Genetic Pathways Associated with Psoriasis.J Invest Dermatol. 2016 Mar;136(3):593-602. doi: 10.1016/j.jid.2015.11.026. Epub 2015 Dec 29.
354 Matrix metalloproteinase-19 expression in normal and diseased skin: dysregulation by epidermal proliferation.J Invest Dermatol. 2003 Nov;121(5):989-96. doi: 10.1046/j.1523-1747.2003.12526.x.
355 Burden of chronic urticaria relative to psoriasis in five European countries.J Eur Acad Dermatol Venereol. 2018 Feb;32(2):282-290. doi: 10.1111/jdv.14584. Epub 2017 Oct 12.
356 Altered expression of matrix remodelling associated 7 (MXRA7) in psoriatic epidermis: Evidence for a protective role in the psoriasis imiquimod mouse model.Exp Dermatol. 2018 Sep;27(9):1038-1042. doi: 10.1111/exd.13687.
357 Non-M protein(s) on the cell wall and membrane of group A streptococci induce(s) IFN-gamma production by dermal CD4+ T cells in psoriasis.Arch Dermatol Res. 2001 Apr;293(4):165-70. doi: 10.1007/s004030100218.
358 Comparison of Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Anxiety/Depression Scale (SAS/SDS) in Evaluating Anxiety and Depression in Patients with Psoriatic Arthritis.Dermatology. 2020;236(2):170-178. doi: 10.1159/000498848. Epub 2019 Aug 21.
359 Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.Circ Cardiovasc Genet. 2009 Apr;2(2):134-41. doi: 10.1161/CIRCGENETICS.108.825273. Epub 2009 Feb 12.
360 A CD40 and an NCOA5 gene polymorphism confer susceptibility to psoriasis in a Southern European population: a case-control study.Hum Immunol. 2011 Sep;72(9):761-5. doi: 10.1016/j.humimm.2011.05.014. Epub 2011 May 24.
361 A preliminary examination of the role of NFAT 3 in human skin, cultured keratocytes and dermal fibroblasts.J Cutan Pathol. 2010 Sep;37(9):e21-36. doi: 10.1111/j.1600-0560.2009.01313.x.
362 Association with Genetic Variants in the IL-23 and NF-B Pathways Discriminates between Mild and Severe Psoriasis Skin Disease.J Invest Dermatol. 2015 Aug;135(8):1969-1976. doi: 10.1038/jid.2015.103. Epub 2015 Mar 19.
363 Adaptive homeostasis of the vitamin D-vitamin D nuclear receptor axis in 8-methoxypsoralen-induced hepatotoxicity. Toxicol Appl Pharmacol. 2019 Jan 1;362:150-158. doi: 10.1016/j.taap.2018.11.002. Epub 2018 Nov 10.
364 Novel roles of NM23 proteins in skin homeostasis, repair and disease.Oncogene. 2007 Jan 25;26(4):532-42. doi: 10.1038/sj.onc.1209822. Epub 2006 Jul 24.
365 Overexpression and potential roles of NRIP1 in psoriasis.Oncotarget. 2016 Nov 8;7(45):74236-74246. doi: 10.18632/oncotarget.12371.
366 Role of neurturin in spontaneous itch and increased nonpeptidergic intraepidermal fiber density in a mouse model of psoriasis.Pain. 2017 Nov;158(11):2196-2202. doi: 10.1097/j.pain.0000000000001025.
367 Epigenetic regulation of OAS2 shows disease-specific DNA methylation profiles at individual CpG sites.Sci Rep. 2016 Aug 30;6:32579. doi: 10.1038/srep32579.
368 Unraveling the genetics of complex diseases: susceptibility genes for rheumatoid arthritis and psoriasis.Semin Immunol. 2009 Dec;21(6):318-27. doi: 10.1016/j.smim.2009.04.002. Epub 2009 May 14.
369 Early clinical response to tofacitinib treatment as a predictor of subsequent efficacy: Results from two phase 3 studies of patients with moderate-to-severe plaque psoriasis.J Dermatolog Treat. 2017 Feb;28(1):3-7. doi: 10.1080/09546634.2016.1214671. Epub 2016 Aug 18.
370 Polymorphisms in the interleukin-20 gene: relationships to plaque-type psoriasis.Genes Immun. 2004 Mar;5(2):117-21. doi: 10.1038/sj.gene.6364046.
371 Dimethyl fumarate and vitamin D derivatives cooperatively enhance VDR and Nrf2 signaling in differentiating AML cells in vitro and inhibit leukemia progression in a xenograft mouse model.J Steroid Biochem Mol Biol. 2019 Apr;188:8-16. doi: 10.1016/j.jsbmb.2018.11.017. Epub 2018 Nov 30.
372 Affinity of 22-oxa-1,25(OH)2D3 for 1,25-dihydroxyvitamin D receptor and its effects on the synthesis of osteocalcin in human osteosarcoma cells.Biochem Biophys Res Commun. 1990 Jun 15;169(2):629-35. doi: 10.1016/0006-291x(90)90377-y.
373 Overexpressed fibulin-3 contributes to the pathogenesis of psoriasis by promoting angiogenesis.Clin Exp Dermatol. 2019 Jun;44(4):e64-e72. doi: 10.1111/ced.13720. Epub 2018 Aug 26.
374 Inositoylated platelet-activating factor (Ino-C2-PAF) modulates dynamic lymphocyte-endothelial cell interactions and alleviates psoriasis-like skin inflammation in two complementary mouse models.J Invest Dermatol. 2014 Oct;134(10):2510-2520. doi: 10.1038/jid.2014.170. Epub 2014 Apr 8.
375 Podoplanin in Inflammation and Cancer.Int J Mol Sci. 2019 Feb 6;20(3):707. doi: 10.3390/ijms20030707.
376 The cargo protein MAP17 (PDZK1IP1) regulates the immune microenvironment.Oncotarget. 2017 Oct 6;8(58):98580-98597. doi: 10.18632/oncotarget.21651. eCollection 2017 Nov 17.
377 Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families.Exp Dermatol. 2009 Feb;18(2):109-15. doi: 10.1111/j.1600-0625.2008.00769.x. Epub 2008 Jul 17.
378 Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21.Hum Genet. 2006 Mar;119(1-2):113-25. doi: 10.1007/s00439-005-0115-8. Epub 2005 Dec 17.
379 Serum elafin as a potential inflammatory marker in psoriasis.Int J Dermatol. 2019 Feb;58(2):205-209. doi: 10.1111/ijd.14217. Epub 2018 Sep 9.
380 Regulation of the psoriatic chemokine CCL20 by E3 ligases Trim32 and Piasy in keratinocytes.J Invest Dermatol. 2010 May;130(5):1384-90. doi: 10.1038/jid.2009.416. Epub 2010 Jan 7.
381 Crossed looks on the dermatologist's position and the patient's preoccupations as to psoriasis and pregnancy: preliminary results of the PREGNAN-PSO study.J Eur Acad Dermatol Venereol. 2019 May;33(5):880-885. doi: 10.1111/jdv.15423. Epub 2019 Feb 27.
382 Characterization and differentiation-dependent regulation of secreted phospholipases A in human keratinocytes and in healthy and psoriatic human skin.J Invest Dermatol. 2005 Jan;124(1):204-11. doi: 10.1111/j.0022-202X.2004.23513.x.
383 Epidermal phospholipase C1 regulates granulocyte counts and systemic interleukin-17 levels in mice.Nat Commun. 2012 Jul 17;3:963. doi: 10.1038/ncomms1960.
384 Splicing factors differentially expressed in psoriasis alter mRNA maturation of disease-associated EDA+fibronectin.Mol Cell Biochem. 2017 Dec;436(1-2):189-199. doi: 10.1007/s11010-017-3090-1. Epub 2017 Jun 6.
385 The proteasome maturation protein POMP increases proteasome assembly and activity in psoriatic lesional skin.J Dermatol Sci. 2017 Oct;88(1):10-19. doi: 10.1016/j.jdermsci.2017.04.009. Epub 2017 Apr 30.
386 Elevated platelet activation in patients with atopic dermatitis and psoriasis: increased plasma levels of beta-thromboglobulin and platelet factor 4.Allergol Int. 2008 Dec;57(4):391-6. doi: 10.2332/allergolint.O-08-537. Epub 2008 Dec 1.
387 MiR-548a-3p Promotes Keratinocyte Proliferation Targeting PPP3R1 after Being Induced by IL-22.Inflammation. 2018 Mar;41(2):496-504. doi: 10.1007/s10753-017-0705-3.
388 NF-B-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis.Nat Commun. 2015 Jul 3;6:7652. doi: 10.1038/ncomms8652.
389 Prokineticin 2 Plays a Pivotal Role in Psoriasis.EBioMedicine. 2016 Nov;13:248-261. doi: 10.1016/j.ebiom.2016.10.022. Epub 2016 Oct 19.
390 Association of skin barrier genes within the PSORS4 locus is enriched in Singaporean Chinese with early-onset psoriasis.J Invest Dermatol. 2009 Mar;129(3):606-14. doi: 10.1038/jid.2008.273. Epub 2008 Sep 11.
391 Role of ceramides in barrier function of healthy and diseased skin.Am J Clin Dermatol. 2005;6(4):215-23. doi: 10.2165/00128071-200506040-00002.
392 HLA-C*06:02-independent, gender-related association of PSORS1C3 and PSORS1C1/CDSN single-nucleotide polymorphisms with risk and severity of psoriasis.Mol Genet Genomics. 2018 Aug;293(4):957-966. doi: 10.1007/s00438-018-1435-4. Epub 2018 Mar 27.
393 Correlation of HLA-Cw*06 allele frequency with some clinical features of psoriasis vulgaris in the population of northern Poland.J Appl Genet. 2004;45(4):473-6.
394 Pituitary tumor transforming gene PTTG2 induces psoriasis by regulating vimentin and E-cadherin expression.Int J Clin Exp Pathol. 2015 Sep 1;8(9):10887-93. eCollection 2015.
395 Evidence on the direct correlation between miR-31 and IL-22 axis in IMQ-induced psoriasis.Exp Dermatol. 2019 Nov;28(11):1336-1340. doi: 10.1111/exd.14001. Epub 2019 Oct 22.
396 A Framework for Multi-Omic Prediction ofTreatment Response to Biologic Therapyfor Psoriasis.J Invest Dermatol. 2019 Jan;139(1):100-107. doi: 10.1016/j.jid.2018.04.041. Epub 2018 Jul 17.
397 Loss of the Epigenetic Mark 5-hmC in Psoriasis: Implications for Epidermal Stem Cell Dysregulation.J Invest Dermatol. 2020 Jun;140(6):1266-1275.e3. doi: 10.1016/j.jid.2019.10.016. Epub 2019 Dec 11.
398 Analysis of serum chemerin concentrations in psoriatic patients in relation to metabolic abnormalities.Postepy Dermatol Alergol. 2019 Oct;36(5):531-537. doi: 10.5114/ada.2019.89503. Epub 2019 Nov 12.
399 Expression and potential role of cellular retinol binding protein I in psoriasis.Oncotarget. 2018 Dec 4;9(95):36736-36749. doi: 10.18632/oncotarget.26314. eCollection 2018 Dec 4.
400 Biomarkers of Inflammation in Obesity-Psoriatic Patients.Mediators Inflamm. 2019 May 28;2019:7353420. doi: 10.1155/2019/7353420. eCollection 2019.
401 RNase 7 downregulates TH2 cytokine production by activated human T cells.Allergy. 2017 Nov;72(11):1694-1703. doi: 10.1111/all.13173. Epub 2017 Jun 21.
402 The application of strand invasion phenomenon, directed by peptide nucleic acid (PNA) and single-stranded DNA binding protein (SSB) for the recognition of specific sequences of human endogenous retroviral HERV-W family.J Mol Recognit. 2017 May;30(5). doi: 10.1002/jmr.2600. Epub 2016 Dec 6.
403 Maresin-1 suppresses imiquimod-induced skin inflammation by regulating IL-23 receptor expression.Sci Rep. 2018 Apr 3;8(1):5522. doi: 10.1038/s41598-018-23623-9.
404 Can signal peptide-CUB-EGF domain-containing protein (SCUBE) levels be a marker of angiogenesis in patients with psoriasis?.Arch Dermatol Res. 2017 Apr;309(3):203-207. doi: 10.1007/s00403-017-1722-7. Epub 2017 Feb 25.
405 Association analyses identify six new psoriasis susceptibility loci in the Chinese population.Nat Genet. 2010 Nov;42(11):1005-9. doi: 10.1038/ng.690. Epub 2010 Oct 17.
406 Tristetraprolin expression by keratinocytes controls local and systemic inflammation.JCI Insight. 2017 Jun 2;2(11):e92979. doi: 10.1172/jci.insight.92979. eCollection 2017 Jun 2.
407 Innate immune adaptor MyD88 deficiency prevents skin inflammation in SHARPIN-deficient mice.Cell Death Differ. 2019 Mar;26(4):741-750. doi: 10.1038/s41418-018-0159-7. Epub 2018 Jul 23.
408 Lesional upregulation of SLURP1 immunostaining parallels disease severity in psoriasis vulgaris patients.J Dtsch Dermatol Ges. 2018 Nov;16(11):1329-1337. doi: 10.1111/ddg.13682.
409 notch2, notch4 gene polymorphisms in psoriasis vulgaris.Eur J Dermatol. 2013 Apr 1;23(2):146-53. doi: 10.1684/ejd.2013.1985.
410 Effects of Human Mesenchymal Stem Cells Transduced with Superoxide Dismutase on Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice.Antioxid Redox Signal. 2016 Feb 10;24(5):233-48. doi: 10.1089/ars.2015.6368. Epub 2015 Nov 18.
411 TNF- and IL-17A induce the expression of lympho-epithelial Kazal-type inhibitor in epidermal keratinocytes.J Dermatol Sci. 2019 Oct;96(1):26-32. doi: 10.1016/j.jdermsci.2019.08.007. Epub 2019 Aug 21.
412 The serine protease inhibitor of Kazal-type 7 (SPINK7) is expressed in human skin.Arch Dermatol Res. 2017 Nov;309(9):767-771. doi: 10.1007/s00403-017-1773-9. Epub 2017 Aug 29.
413 Multi-omics study in monozygotic twins confirm the contribution of de novo mutation to psoriasis.J Autoimmun. 2020 Jan;106:102349. doi: 10.1016/j.jaut.2019.102349. Epub 2019 Oct 16.
414 Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice.J Clin Invest. 2009 Apr;119(4):899-910. doi: 10.1172/JCI37771. Epub 2009 Mar 23.
415 'Psoriasis 1' reduces psoriasislike skin inflammation by inhibiting the VDRmediated nuclear NFB and STAT signaling pathways.Mol Med Rep. 2018 Sep;18(3):2733-2743. doi: 10.3892/mmr.2018.9262. Epub 2018 Jul 9.
416 microRNA-130a Promotes Human Keratinocyte Viability and Migration and Inhibits Apoptosis Through Direct Regulation of STK40-Mediated NF-B Pathway and Indirect Regulation of SOX9-Meditated JNK/MAPK Pathway: A Potential Role in Psoriasis.DNA Cell Biol. 2017 Mar;36(3):219-226. doi: 10.1089/dna.2016.3517. Epub 2017 Jan 13.
417 T-cell activation RhoGTPase-activating protein plays an important role in T(H)17-cell differentiation.Immunol Cell Biol. 2017 Sep;95(8):729-735. doi: 10.1038/icb.2017.27. Epub 2017 May 2.
418 The mRNA expression and promoter methylation status of the p16 gene in colony-forming cells with high proliferative potential in patients with psoriasis.Clin Exp Dermatol. 2007 Nov;32(6):702-8. doi: 10.1111/j.1365-2230.2007.02458.x. Epub 2007 May 17.
419 Expression of tolerance associated gene-1, a mitochondrial protein inhibiting T cell activation, can be used to predict response to immune modulating therapies.J Immunol. 2009 Sep 15;183(6):4077-87. doi: 10.4049/jimmunol.0804351. Epub 2009 Aug 14.
420 Inflammatory peeling skin syndrome caused by homozygous genomic deletion in the PSORS1 region encompassing the CDSN gene.Exp Dermatol. 2014 Jan;23(1):60-3. doi: 10.1111/exd.12292.
421 Novel methotrexate soft nanocarrier/fractional erbium YAG laser combination for clinical treatment of plaque psoriasis.Artif Cells Nanomed Biotechnol. 2018;46(sup1):996-1002. doi: 10.1080/21691401.2018.1440236. Epub 2018 Feb 15.
422 Interferon- decreases ceramides with long-chain fatty acids: possible involvement in atopic dermatitis and psoriasis.J Invest Dermatol. 2014 Mar;134(3):712-718. doi: 10.1038/jid.2013.364. Epub 2013 Sep 5.
423 Ginsenoside Rg1 abolish imiquimod-induced psoriasis-like dermatitis in BALB/c mice via downregulating NF-B signaling pathway.J Food Biochem. 2019 Nov;43(11):e13032. doi: 10.1111/jfbc.13032. Epub 2019 Sep 9.
424 Loss of TIPE2 Has Opposing Effects on the Pathogenesis of Autoimmune Diseases.Front Immunol. 2019 Sep 24;10:2284. doi: 10.3389/fimmu.2019.02284. eCollection 2019.
425 CD30L/CD30 protects against psoriasiform skin inflammation by suppressing Th17-related cytokine production by V4(+) T cells.J Autoimmun. 2019 Jul;101:70-85. doi: 10.1016/j.jaut.2019.04.009. Epub 2019 Apr 18.
426 Rapamycin ameliorates psoriasis by regulating the expression and methylation levels of tropomyosin via ERK1/2 and mTOR pathways in vitro and in vivo.Exp Dermatol. 2018 Oct;27(10):1112-1119. doi: 10.1111/exd.13745. Epub 2018 Aug 3.
427 The Act1 D10N missense variant impairs CD40 signaling in human B-cells.Genes Immun. 2019 Jan;20(1):23-31. doi: 10.1038/s41435-017-0007-7. Epub 2018 Jan 5.
428 TREX through Cutaneous HealthandDisease.J Invest Dermatol. 2016 Dec;136(12):2337-2339. doi: 10.1016/j.jid.2016.06.628.
429 Structural insights into the duplex DNA processing of TREX2.Nucleic Acids Res. 2018 Dec 14;46(22):12166-12176. doi: 10.1093/nar/gky970.
430 E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.J Invest Dermatol. 2018 Dec;138(12):2568-2577. doi: 10.1016/j.jid.2018.05.016. Epub 2018 May 31.
431 Trim32 Deficiency Enhances Th2 Immunity and Predisposes to Features of Atopic Dermatitis.J Invest Dermatol. 2017 Feb;137(2):359-366. doi: 10.1016/j.jid.2016.09.020. Epub 2016 Oct 5.
432 Glucocorticoids and Glucocorticoid-Induced-Leucine-Zipper (GILZ) in Psoriasis.Front Immunol. 2019 Sep 13;10:2220. doi: 10.3389/fimmu.2019.02220. eCollection 2019.
433 The Tetratricopeptide repeat domain 7 gene is mutated in flaky skin mice: a model for psoriasis, autoimmunity, and anemia.Exp Biol Med (Maywood). 2005 Oct;230(9):659-67. doi: 10.1177/153537020523000908.
434 Adaptive and Innate Immunity in Psoriasis and Other Inflammatory Disorders.Front Immunol. 2019 Jul 26;10:1764. doi: 10.3389/fimmu.2019.01764. eCollection 2019.
435 Safety and efficacy of halobetasol propionate lotion 0.01% in the treatment of moderate to severe plaque psoriasis: a pooled analysis of 2 phase 3 studies.Cutis. 2019 Feb;103(2):111-116.
436 CXCL17 Attenuates Imiquimod-Induced Psoriasis-like Skin Inflammation by Recruiting Myeloid-Derived Suppressor Cells and Regulatory T Cells.J Immunol. 2017 May 15;198(10):3897-3908. doi: 10.4049/jimmunol.1601607. Epub 2017 Apr 7.
437 Silencing KRT16 inhibits keratinocyte proliferation and VEGF secretion in psoriasis via inhibition of ERK signaling pathway.Kaohsiung J Med Sci. 2019 May;35(5):284-296. doi: 10.1002/kjm2.12034. Epub 2019 Apr 3.
438 In vivo anti-psoriatic activity, biodistribution, sub-acute and sub-chronic toxicity studies of orally administered methotrexate loaded chitin nanogel in comparison with methotrexate tablet.Int J Biol Macromol. 2018 Apr 15;110:259-268. doi: 10.1016/j.ijbiomac.2018.01.036. Epub 2018 Feb 2.
439 IB is a key player in the antipsoriatic effects of secukinumab.J Allergy Clin Immunol. 2020 Jan;145(1):379-390. doi: 10.1016/j.jaci.2019.09.029. Epub 2019 Oct 14.
440 RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.EMBO Mol Med. 2017 May;9(5):589-604. doi: 10.15252/emmm.201607027.
441 Gene from a psoriasis susceptibility locus primes the skin for inflammation.Sci Transl Med. 2010 Dec 8;2(61):61ra90. doi: 10.1126/scitranslmed.3001108.
442 Serum levels of psoriasin (S100A7) and koebnerisin (S100A15) as potential markers of atherosclerosis in patients with psoriasis.Clin Exp Dermatol. 2018 Apr;43(3):262-267. doi: 10.1111/ced.13370. Epub 2018 Jan 14.
443 Janus kinase/signal transducer and activator of transcription pathways in spondyloarthritis.Curr Opin Rheumatol. 2017 Jul;29(4):311-316. doi: 10.1097/BOR.0000000000000399.
444 ROC analysis of selected matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in psoriatic patients.Postepy Dermatol Alergol. 2018 Apr;35(2):167-173. doi: 10.5114/ada.2018.75238. Epub 2018 Apr 24.
445 A recessive form of the Ehlers-Danlos syndrome caused by tenascin-X deficiency. N Engl J Med. 2001 Oct 18;345(16):1167-75. doi: 10.1056/NEJMoa002939.