Details of the Drug Combination

General Information of Drug Combination (ID: DC04YOF)

• Drug Combination Name: Azacitidine + Dasatinib
• Indication: Acute Myeloid Leukemia; Status: Phase 1 [1]
• Component Drugs:
  Azacitidine (DMTA5OE): Small molecular drug
  Dasatinib (DMJV2EK): Small molecular drug

Molecular Interaction Atlas of This Drug Combination

Indication(s) of Azacitidine

Disease Entry	ICD 11	Status	REF
Acute myelogenous leukaemia	2A41	Approved	[2]
Chronic myelomonocytic leukemia	N.A.	Approved	[2]
Leukemia	N.A.	Approved	[2]
Myelodysplastic syndrome	2A37	Approved	[3]
Myeloproliferative neoplasm	2A20	Approved	[2]
Plasma cell myeloma	2A83.1	Approved	[2]

Azacitidine Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
DNA [cytosine-5]-methyltransferase (DNMT)	TTHVCUP	NOUNIPROTAC	Inhibitor	[12]

Azacitidine Interacts with 2 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Cytidine aminohydrolase (CDA)	DEKEDRC	CDD_HUMAN	Metabolism	[13]
Cytidine deaminase (cdd)	DEYILK4	E0TLJ6_MYCHH	Metabolism	[14]

Azacitidine Interacts with 275 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
Bcl-2-like protein 1 (BCL2L1)	OTRC5K9O	B2CL1_HUMAN	Affects Expression	[15]
Cytochrome P450 1A1 (CYP1A1)	OTE4EFH8	CP1A1_HUMAN	Increases Expression	[16]
Cytochrome P450 1A2 (CYP1A2)	OTLLBX48	CP1A2_HUMAN	Increases Expression	[16]
Aryl hydrocarbon receptor (AHR)	OTFE4EYE	AHR_HUMAN	Increases Expression	[16]
Cytochrome P450 1B1 (CYP1B1)	OTYXFLSD	CP1B1_HUMAN	Increases Expression	[16]
Sulfotransferase 1C2 (SULT1C2)	OT07MMZS	ST1C2_HUMAN	Increases Expression	[8]
Phospholipid phosphatase 1 (PLPP1)	OT0IIMI5	PLPP1_HUMAN	Increases Expression	[8]
Tectonin beta-propeller repeat-containing protein 2 (TECPR2)	OT1UFECZ	TCPR2_HUMAN	Increases Expression	[8]
TBC1 domain family member 4 (TBC1D4)	OTK66C40	TBCD4_HUMAN	Decreases Expression	[8]
Multiple epidermal growth factor-like domains protein 6 (MEGF6)	OTEUYTP1	MEGF6_HUMAN	Decreases Expression	[8]
Stanniocalcin-2 (STC2)	OT86YP8G	STC2_HUMAN	Decreases Expression	[8]
Integrin beta-2 (ITGB2)	OTEKPEPR	ITB2_HUMAN	Decreases Expression	[8]
Protein S100-A9 (S100A9)	OTOARHCS	S10A9_HUMAN	Increases Expression	[8]
Receptor-type tyrosine-protein phosphatase C (PTPRC)	OT6KOR77	PTPRC_HUMAN	Increases Expression	[8]
Delta-aminolevulinic acid dehydratase (ALAD)	OTHM9GSH	HEM2_HUMAN	Decreases Expression	[8]
Hepatocyte growth factor (HGF)	OTGHUA23	HGF_HUMAN	Increases Expression	[8]
Heat shock 70 kDa protein 6 (HSPA6)	OTH4S7WB	HSP76_HUMAN	Increases Expression	[8]
Gamma-aminobutyric acid receptor subunit beta-1 (GABRB1)	OT4L2SSB	GBRB1_HUMAN	Increases Expression	[8]
Transcription factor E3 (TFE3)	OTM99ZWH	TFE3_HUMAN	Increases Expression	[8]
Pro-thyrotropin-releasing hormone (TRH)	OT02UY2V	TRH_HUMAN	Decreases Expression	[8]
Protein S100-P (S100P)	OTJCXNJG	S100P_HUMAN	Increases Expression	[8]
Protein PML (PML)	OT6SM2GD	PML_HUMAN	Increases Expression	[8]
DNA-binding protein inhibitor ID-1 (ID1)	OTKGNZN5	ID1_HUMAN	Increases Expression	[8]
Cyclin-dependent kinase 4 inhibitor B (CDKN2B)	OTAG24N1	CDN2B_HUMAN	Decreases Methylation	[8]
LIM and senescent cell antigen-like-containing domain protein 1 (LIMS1)	OT729S0T	LIMS1_HUMAN	Increases Expression	[8]
E3 SUMO-protein ligase RanBP2 (RANBP2)	OTFG5CVF	RBP2_HUMAN	Increases Expression	[8]
Cyclin-dependent kinase inhibitor 1C (CDKN1C)	OTASTJ3Q	CDN1C_HUMAN	Increases Expression	[8]
Ras-related protein Rab-13 (RAB13)	OTIQ484I	RAB13_HUMAN	Decreases Methylation	[8]
Lysozyme C (LYZ)	OTD7H0G6	LYSC_HUMAN	Increases Expression	[8]
Claudin-10 (CLDN10)	OT2CVAKY	CLD10_HUMAN	Decreases Expression	[8]
Sushi repeat-containing protein SRPX (SRPX)	OT5B9LXS	SRPX_HUMAN	Decreases Expression	[8]
Protein delta homolog 1 (DLK1)	OTE1VLNB	DLK1_HUMAN	Decreases Methylation	[8]
DNA-binding protein inhibitor ID-3 (ID3)	OTUULW5Z	ID3_HUMAN	Increases Expression	[8]
Collagen alpha-1(XIV) chain (COL14A1)	OTLNJ13O	COEA1_HUMAN	Increases Expression	[8]
Equilibrative nucleoside transporter 2 (SLC29A2)	OTUAOB8T	S29A2_HUMAN	Decreases Expression	[8]
Cytohesin-1 (CYTH1)	OTYH9NRJ	CYH1_HUMAN	Increases Expression	[8]
C3a anaphylatoxin chemotactic receptor (C3AR1)	OT8J0TF8	C3AR_HUMAN	Increases Expression	[8]
DNA dC->dU-editing enzyme APOBEC-3F (APOBEC3F)	OT750IJM	ABC3F_HUMAN	Increases Expression	[8]
Angiogenic factor with G patch and FHA domains 1 (AGGF1)	OTA7U2T8	AGGF1_HUMAN	Increases Expression	[8]
E3 ubiquitin-protein ligase Praja-1 (PJA1)	OTFKTMEI	PJA1_HUMAN	Increases Expression	[8]
Caspase-10 (CASP10)	OTE6J88E	CASPA_HUMAN	Increases Expression	[8]
Tetraspanin-32 (TSPAN32)	OTSXW7EW	TSN32_HUMAN	Decreases Expression	[8]
Tribbles homolog 1 (TRIB1)	OTPEO17G	TRIB1_HUMAN	Decreases Expression	[8]
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LITAF)	OTT5JX1F	LITAF_HUMAN	Decreases Expression	[8]
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1A)	OTVTB5R5	PI51A_HUMAN	Decreases Expression	[8]
Centromere protein O (CENPO)	OTXAH83Y	CENPO_HUMAN	Increases Expression	[8]
Iron-sulfur cluster assembly 1 homolog, mitochondrial (ISCA1)	OTU230MC	ISCA1_HUMAN	Increases Expression	[8]
E3 ubiquitin-protein ligase TRIM8 (TRIM8)	OTS6JFR0	TRIM8_HUMAN	Increases Expression	[8]
Uncharacterized protein C6orf62 (C6ORF62)	OTGK4G35	CF062_HUMAN	Increases Expression	[8]
Metal transporter CNNM2 (CNNM2)	OTZHO8WU	CNNM2_HUMAN	Decreases Expression	[8]
Pantothenate kinase 3 (PANK3)	OT77CFJ6	PANK3_HUMAN	Decreases Expression	[8]
DNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G)	OT410VP5	ABC3G_HUMAN	Increases Expression	[8]
Neuritin (NRN1)	OTWJG0SO	NRN1_HUMAN	Decreases Expression	[8]
NTF2-related export protein 2 (NXT2)	OTK82YVT	NXT2_HUMAN	Increases Expression	[8]
THUMP domain-containing protein 1 (THUMPD1)	OTKU8KWH	THUM1_HUMAN	Increases Expression	[8]
Protein FAM8A1 (FAM8A1)	OT1QVTGS	FA8A1_HUMAN	Increases Expression	[8]
Type 2 lactosamine alpha-2,3-sialyltransferase (ST3GAL6)	OTB17Q43	SIA10_HUMAN	Increases Expression	[8]
Methionine-R-sulfoxide reductase B2, mitochondrial (MSRB2)	OTURGRA8	MSRB2_HUMAN	Increases Expression	[8]
Mitotic spindle assembly checkpoint protein MAD1 (MAD1L1)	OTJCX8K9	MD1L1_HUMAN	Decreases Expression	[8]
Signal-regulatory protein beta-1 (SIRPB1)	OTGHALWJ	SIRB1_HUMAN	Decreases Expression	[9]
Syntenin-1 (SDCBP)	OTS3NCC5	SDCB1_HUMAN	Decreases Expression	[9]
Complexin-1 (CPLX1)	OT7UIGTP	CPLX1_HUMAN	Increases Expression	[9]
Nephrocystin-1 (NPHP1)	OTZHCFFQ	NPHP1_HUMAN	Increases Expression	[9]
Phosphatase and actin regulator 2 (PHACTR2)	OTWMX2A8	PHAR2_HUMAN	Increases Expression	[9]
Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1)	OT4TMERS	NFAC1_HUMAN	Increases Expression	[9]
Acyl-CoA 6-desaturase (FADS2)	OTUX531P	FADS2_HUMAN	Decreases Expression	[9]
Metalloproteinase inhibitor 1 (TIMP1)	OTOXC51H	TIMP1_HUMAN	Increases Expression	[9]
Cystatin-C (CST3)	OTNZ6AO4	CYTC_HUMAN	Increases Expression	[9]
Cystatin-S (CST4)	OTXXM8EH	CYTS_HUMAN	Increases Expression	[9]
Interstitial collagenase (MMP1)	OTI4I2V1	MMP1_HUMAN	Increases Expression	[9]
Integrin beta-1 (ITGB1)	OT6G1IAR	ITB1_HUMAN	Decreases Expression	[9]
Keratin, type II cytoskeletal 8 (KRT8)	OTTM4X11	K2C8_HUMAN	Increases Expression	[9]
Neurofilament light polypeptide (NEFL)	OTQESJV4	NFL_HUMAN	Increases Expression	[9]
Protein disulfide-isomerase (P4HB)	OTTYNYPF	PDIA1_HUMAN	Increases Expression	[9]
Decorin (DCN)	OTWLJL7K	PGS2_HUMAN	Decreases Expression	[9]
Profilin-1 (PFN1)	OTHTGA1H	PROF1_HUMAN	Increases Expression	[9]
Proto-oncogene tyrosine-protein kinase receptor Ret (RET)	OTLU040A	RET_HUMAN	Decreases Expression	[9]
Tropomyosin beta chain (TPM2)	OTA1L0P8	TPM2_HUMAN	Increases Expression	[9]
Transcription factor Sp1 (SP1)	OTISPT4X	SP1_HUMAN	Decreases Expression	[9]
Keratin, type I cytoskeletal 19 (KRT19)	OTDGDQ75	K1C19_HUMAN	Increases Expression	[9]
Insulin-like growth factor-binding protein 1 (IGFBP1)	OT6UQV2K	IBP1_HUMAN	Increases Expression	[9]
Small ribosomal subunit protein uS2 (RPSA)	OTJZHEGT	RSSA_HUMAN	Decreases Expression	[9]
Glycodelin (PAEP)	OTQA0NV4	PAEP_HUMAN	Decreases Expression	[9]
E3 SUMO-protein ligase EGR2 (EGR2)	OTAVQ78J	EGR2_HUMAN	Increases Expression	[9]
Pregnancy-specific beta-1-glycoprotein 1 (PSG1)	OT1U4ZZW	PSG1_HUMAN	Increases Expression	[9]
Collagen alpha-3(VI) chain (COL6A3)	OTAS6R6I	CO6A3_HUMAN	Decreases Expression	[9]
Parathyroid hormone-related protein (PTHLH)	OTI1JF13	PTHR_HUMAN	Decreases Expression	[9]
Plastin-3 (PLS3)	OTYBM4PK	PLST_HUMAN	Decreases Expression	[9]
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (MTHFD2)	OT1LQSGX	MTDC_HUMAN	Decreases Expression	[9]
Pyruvate kinase PKM (PKM)	OTLHHMC2	KPYM_HUMAN	Increases Expression	[9]
Carboxypeptidase E (CPE)	OTXNTV79	CBPE_HUMAN	Increases Expression	[9]
High mobility group protein HMG-I/HMG-Y (HMGA1)	OTQUSHPX	HMGA1_HUMAN	Increases Expression	[9]
Gap junction alpha-1 protein (GJA1)	OTT94MKL	CXA1_HUMAN	Decreases Expression	[9]
Desmin (DES)	OTI09KBW	DESM_HUMAN	Increases Expression	[9]
Plasma membrane calcium-transporting ATPase 1 (ATP2B1)	OT5MXG9W	AT2B1_HUMAN	Decreases Expression	[9]
Cyclin-A2 (CCNA2)	OTPHHYZJ	CCNA2_HUMAN	Decreases Expression	[9]
5'-nucleotidase (NT5E)	OT7J5LT6	5NTD_HUMAN	Increases Expression	[9]
Fibroblast growth factor 7 (FGF7)	OTGK6ANL	FGF7_HUMAN	Decreases Expression	[9]
Insulin-like growth factor-binding protein 4 (IGFBP4)	OT2HZRBD	IBP4_HUMAN	Increases Expression	[9]
Transcription elongation factor A protein 1 (TCEA1)	OTBFO594	TCEA1_HUMAN	Decreases Expression	[9]
G1/S-specific cyclin-D1 (CCND1)	OT8HPTKJ	CCND1_HUMAN	Increases Expression	[9]
Tenascin (TNC)	OTK4FSHR	TENA_HUMAN	Decreases Expression	[9]
V-type proton ATPase 16 kDa proteolipid subunit c (ATP6V0C)	OTKPL09B	VATL_HUMAN	Increases Expression	[9]
Protein ITPRID2 (ITPRID2)	OTO3JDX5	ITPI2_HUMAN	Increases Expression	[9]
Dual specificity protein phosphatase 1 (DUSP1)	OTN6BR75	DUS1_HUMAN	Increases Expression	[9]
Interleukin-12 subunit beta (IL12B)	OT0JF8A3	IL12B_HUMAN	Increases Expression	[9]
Neurotensin/neuromedin N (NTS)	OTPGDNQS	NEUT_HUMAN	Decreases Expression	[9]
Guanylate-binding protein 2 (GBP2)	OTVU4G07	GBP2_HUMAN	Decreases Expression	[9]
MHC class II transactivator (CIITA)	OTRJNZFO	C2TA_HUMAN	Increases Expression	[9]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Increases Expression	[9]
Exosome RNA helicase MTR4 (MTREX)	OTSQY30V	MTREX_HUMAN	Increases Expression	[9]
Alpha-S1-casein (CSN1S1)	OTXOW6XJ	CASA1_HUMAN	Increases Expression	[9]
Nuclear receptor-interacting protein 1 (NRIP1)	OTIZOJQV	NRIP1_HUMAN	Decreases Expression	[9]
Homeobox protein Hox-A1 (HOXA1)	OTMSOJ7D	HXA1_HUMAN	Increases Expression	[9]
Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1)	OT6E2OW6	ENTP1_HUMAN	Increases Expression	[9]
Ephrin-A3 (EFNA3)	OTJGOUMZ	EFNA3_HUMAN	Increases Expression	[9]
GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 (ART1)	OT7FBG5W	NAR1_HUMAN	Increases Expression	[9]
Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1)	OTYHXLWZ	BCAT1_HUMAN	Decreases Expression	[9]
Microfibrillar-associated protein 2 (MFAP2)	OTMHVBTV	MFAP2_HUMAN	Decreases Expression	[9]
Laminin subunit beta-2 (LAMB2)	OT71OI2Y	LAMB2_HUMAN	Increases Expression	[9]
NHP2-like protein 1 (SNU13)	OTH56TIH	NH2L1_HUMAN	Increases Expression	[9]
Homeobox protein DLX-6 (DLX6)	OT0FIJHY	DLX6_HUMAN	Increases Expression	[9]
Neurotrypsin (PRSS12)	OT1MYL3L	NETR_HUMAN	Decreases Expression	[9]
Elongation factor 1-alpha 1 (EEF1A1)	OT00THXS	EF1A1_HUMAN	Decreases Expression	[9]
Microtubule-associated protein 1A (MAP1A)	OTHO8K43	MAP1A_HUMAN	Decreases Expression	[9]
E3 ubiquitin-protein ligase Mdm2 (MDM2)	OTOVXARF	MDM2_HUMAN	Increases Expression	[9]
Cytochrome c oxidase subunit 6A2, mitochondrial (COX6A2)	OTQR5SXD	CX6A2_HUMAN	Increases Expression	[9]
cAMP-responsive element modulator (CREM)	OTJIJ5AL	CREM_HUMAN	Decreases Expression	[9]
Caldesmon (CALD1)	OTNJKJ6Q	CALD1_HUMAN	Increases Expression	[9]
ATP-dependent RNA helicase A (DHX9)	OT5AAOQI	DHX9_HUMAN	Decreases Expression	[9]
Serine/threonine-protein kinase PAK 1 (PAK1)	OT17LZNZ	PAK1_HUMAN	Increases Expression	[9]
Dual specificity mitogen-activated protein kinase kinase 5 (MAP2K5)	OT6T408U	MP2K5_HUMAN	Decreases Expression	[9]
Chitotriosidase-1 (CHIT1)	OTPQR0A6	CHIT1_HUMAN	Increases Expression	[9]
Ras and Rab interactor 1 (RIN1)	OTPBROUD	RIN1_HUMAN	Increases Expression	[9]
Keratin, type I cuticular Ha2 (KRT32)	OTZCGZYT	K1H2_HUMAN	Increases Expression	[9]
Semaphorin-3A (SEMA3A)	OTQJSV7W	SEM3A_HUMAN	Increases Expression	[9]
Ras GTPase-activating protein 3 (RASA3)	OT9C54MN	RASA3_HUMAN	Increases Expression	[9]
Mediator of DNA damage checkpoint protein 1 (MDC1)	OTEUQH4J	MDC1_HUMAN	Increases Expression	[9]
Transmembrane glycoprotein NMB (GPNMB)	OTB7KQKV	GPNMB_HUMAN	Decreases Expression	[9]
Mortality factor 4-like protein 2 (MORF4L2)	OT8OI3EC	MO4L2_HUMAN	Decreases Expression	[9]
kinase isozyme 1, mitochondrial (PDK1)	OTMABK9Z	PDK1_HUMAN	Increases Expression	[9]
Serine/threonine-protein kinase 38 (STK38)	OTKMYCYR	STK38_HUMAN	Decreases Expression	[9]
Serine/threonine-protein phosphatase 2A activator (PTPA)	OTRGFOI7	PTPA_HUMAN	Increases Expression	[9]
Reticulocalbin-1 (RCN1)	OT3JBGAG	RCN1_HUMAN	Decreases Expression	[9]
Olfactory receptor 8B8 (OR8B8)	OTCISNYV	OR8B8_HUMAN	Increases Expression	[9]
Leukotriene B4 receptor 1 (LTB4R)	OT3SRH4H	LT4R1_HUMAN	Decreases Expression	[9]
Serine/arginine-rich splicing factor 7 (SRSF7)	OTRS4W4S	SRSF7_HUMAN	Decreases Expression	[9]
Guanylate kinase (GUK1)	OTLI0HRU	KGUA_HUMAN	Increases Expression	[9]
Filamin A-interacting protein 1-like (FILIP1L)	OTPY8IMS	FIL1L_HUMAN	Decreases Expression	[9]
Nucleolar MIF4G domain-containing protein 1 (NOM1)	OTWZSJJC	NOM1_HUMAN	Decreases Expression	[9]
Opioid growth factor receptor-like protein 1 (OGFRL1)	OT6QGBYE	OGRL1_HUMAN	Increases Expression	[9]
Serine/threonine-protein kinase MRCK alpha (CDC42BPA)	OTCPFOSA	MRCKA_HUMAN	Decreases Expression	[9]
Extracellular sulfatase Sulf-1 (SULF1)	OTJCNCO0	SULF1_HUMAN	Decreases Expression	[9]
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (GCNT2)	OTRUIMC4	GNT2A_HUMAN	Decreases Expression	[9]
Oxidation resistance protein 1 (OXR1)	OTPIDMT3	OXR1_HUMAN	Increases Expression	[9]
Alpha-2,8-sialyltransferase 8B (ST8SIA2)	OTRBBBD8	SIA8B_HUMAN	Decreases Expression	[9]
Type II iodothyronine deiodinase (DIO2)	OTGPNSLH	IOD2_HUMAN	Decreases Expression	[9]
G-patch domain and KOW motifs-containing protein (GPKOW)	OTGS3H0M	GPKOW_HUMAN	Increases Expression	[9]
Rho guanine nucleotide exchange factor 2 (ARHGEF2)	OTBQTFRT	ARHG2_HUMAN	Decreases Expression	[9]
Homogentisate 1,2-dioxygenase (HGD)	OTTKLQOO	HGD_HUMAN	Increases Expression	[9]
Secretory carrier-associated membrane protein 4 (SCAMP4)	OTSCZTJ5	SCAM4_HUMAN	Increases Expression	[9]
Protein bicaudal D homolog 1 (BICD1)	OT78IYPF	BICD1_HUMAN	Decreases Expression	[9]
Ankyrin repeat and SOCS box protein 2 (ASB2)	OTF9LV7L	ASB2_HUMAN	Increases Expression	[9]
Eyes absent homolog 1 (EYA1)	OTHU807A	EYA1_HUMAN	Decreases Expression	[9]
Bcl-2-like protein 13 (BCL2L13)	OT2VRFTM	B2L13_HUMAN	Increases Expression	[9]
RNA helicase Mov10l1 (MOV10L1)	OTP978LK	M10L1_HUMAN	Increases Expression	[9]
Rac GTPase-activating protein 1 (RACGAP1)	OTQE8IEH	RGAP1_HUMAN	Increases Expression	[9]
Ras-related protein Rab-1B (RAB1B)	OTAFCUAS	RAB1B_HUMAN	Increases Expression	[9]
Semaphorin-6C (SEMA6C)	OT1N59T5	SEM6C_HUMAN	Increases Expression	[9]
Sentrin-specific protease 3 (SENP3)	OTFQDOMC	SENP3_HUMAN	Increases Expression	[9]
Ribonuclease P protein subunit p21 (RPP21)	OT53MDNE	RPP21_HUMAN	Increases Expression	[9]
Protocadherin-18 (PCDH18)	OTTLQWRN	PCD18_HUMAN	Decreases Expression	[9]
Protein S100-A14 (S100A14)	OTVFJJ91	S10AE_HUMAN	Decreases Expression	[9]
Tryptase gamma (TPSG1)	OTDESHKT	TRYG1_HUMAN	Decreases Expression	[9]
Rho GTPase-activating protein 35 (ARHGAP35)	OTJ8POG0	RHG35_HUMAN	Increases Expression	[9]
Neuroligin-3 (NLGN3)	OTKDEC1Q	NLGN3_HUMAN	Increases Expression	[9]
Polycystin-2-like protein 1 (PKD2L1)	OT1KJDAT	PK2L1_HUMAN	Increases Expression	[9]
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1)	OTTLJH8W	ATS1_HUMAN	Decreases Expression	[9]
Cytoplasmic phosphatidylinositol transfer protein 1 (PITPNC1)	OT64TTGC	PITC1_HUMAN	Decreases Expression	[9]
Transcription factor SOX-13 (SOX13)	OTCIF6KC	SOX13_HUMAN	Decreases Expression	[9]
Afadin- and alpha-actinin-binding protein (SSX2IP)	OTEIZ7N1	ADIP_HUMAN	Increases Expression	[9]
Transmembrane emp24 domain-containing protein 3 (TMED3)	OTNOPHHC	TMED3_HUMAN	Increases Expression	[9]
Protocadherin beta-4 (PCDHB4)	OTF665E0	PCDB4_HUMAN	Decreases Expression	[9]
Protocadherin beta-14 (PCDHB14)	OTFZF1ST	PCDBE_HUMAN	Decreases Expression	[9]
Adenylate kinase isoenzyme 5 (AK5)	OTTGXLOT	KAD5_HUMAN	Increases Expression	[9]
Albumin (ALB)	OTVMM513	ALBU_HUMAN	Increases Expression	[17]
Alpha-fetoprotein (AFP)	OT9GG3ZI	FETA_HUMAN	Increases Expression	[17]
Cytochrome P450 3A4 (CYP3A4)	OTQGYY83	CP3A4_HUMAN	Increases Expression	[17]
Tyrosine aminotransferase (TAT)	OT2CJ91O	ATTY_HUMAN	Increases Expression	[17]
Hepatocyte nuclear factor 4-alpha (HNF4A)	OTY1TOAB	HNF4A_HUMAN	Increases Expression	[17]
CCAAT/enhancer-binding protein alpha (CEBPA)	OTOM9OE4	CEBPA_HUMAN	Increases Expression	[17]
Hematopoietically-expressed homeobox protein HHEX (HHEX)	OTLIUVYX	HHEX_HUMAN	Increases Expression	[17]
Suppressor of cytokine signaling 3 (SOCS3)	OTY183WJ	SOCS3_HUMAN	Affects Expression	[15]
Telomerase reverse transcriptase (TERT)	OT085VVA	TERT_HUMAN	Decreases Expression	[18]
Aquaporin-9 (AQP9)	OTLGH5ZY	AQP9_HUMAN	Increases Expression	[19]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 (GNG7)	OTHS1L0E	GBG7_HUMAN	Affects Methylation	[20]
Claudin-7 (CLDN7)	OTNE0XHQ	CLD7_HUMAN	Decreases Expression	[21]
Claudin-9 (CLDN9)	OTCKI2IZ	CLD9_HUMAN	Increases Expression	[22]
Myc proto-oncogene protein (MYC)	OTPV5LUK	MYC_HUMAN	Decreases Expression	[18]
Calcitonin (CALCA)	OTZ11LHB	CALC_HUMAN	Decreases Methylation	[23]
Tumor necrosis factor (TNF)	OT4IE164	TNFA_HUMAN	Increases Response To Substance	[24]
Estrogen receptor (ESR1)	OTKLU61J	ESR1_HUMAN	Increases Expression	[25]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Affects Activity	[26]
Interleukin-4 (IL4)	OTOXBWAU	IL4_HUMAN	Affects Methylation	[27]
Interleukin-6 (IL6)	OTUOSCCU	IL6_HUMAN	Affects Methylation	[27]
Tyrosine-protein kinase Fyn (FYN)	OTLSLVZS	FYN_HUMAN	Increases Expression	[28]
Cyclin-dependent kinase 1 (CDK1)	OTW1SC2N	CDK1_HUMAN	Increases Expression	[29]
L-lactate dehydrogenase B chain (LDHB)	OT9B1CT3	LDHB_HUMAN	Increases Expression	[30]
Thyroid peroxidase (TPO)	OTJJLL20	PERT_HUMAN	Increases Expression	[31]
Prostate-specific antigen (KLK3)	OTFGSBFJ	KLK3_HUMAN	Increases Expression	[29]
Histone H1.0 (H1-0)	OTRLJK4Z	H10_HUMAN	Increases Expression	[32]
Interleukin-6 receptor subunit alpha (IL6R)	OTCQL07Z	IL6RA_HUMAN	Affects Expression	[15]
Gamma-enolase (ENO2)	OTRODL0T	ENOG_HUMAN	Decreases Expression	[33]
Androgen receptor (AR)	OTUBKAZZ	ANDR_HUMAN	Increases Expression	[29]
Microtubule-associated protein tau (MAPT)	OTMTP2Z7	TAU_HUMAN	Decreases Expression	[34]
Chromogranin-A (CHGA)	OTXYX5JH	CMGA_HUMAN	Decreases Expression	[33]
Cyclin-dependent kinase 4 (CDK4)	OT7EP05T	CDK4_HUMAN	Decreases Expression	[29]
Cadherin-1 (CDH1)	OTFJMXPM	CADH1_HUMAN	Increases Expression	[35]
G2/mitotic-specific cyclin-B1 (CCNB1)	OT19S7E5	CCNB1_HUMAN	Increases Expression	[33]
15-hydroxyprostaglandin dehydrogenase (HPGD)	OTYZI6JB	PGDH_HUMAN	Decreases Methylation	[36]
Histone H2AX (H2AX)	OT18UX57	H2AX_HUMAN	Increases Expression	[37]
Methylated-DNA--protein-cysteine methyltransferase (MGMT)	OT40A9WH	MGMT_HUMAN	Increases Expression	[38]
Thyrotropin receptor (TSHR)	OT0BC8LB	TSHR_HUMAN	Increases Expression	[31]
Hepatocyte nuclear factor 1-alpha (HNF1A)	OT9DOUKL	HNF1A_HUMAN	Increases Expression	[19]
Fibulin-1 (FBLN1)	OT5MHHOP	FBLN1_HUMAN	Increases Expression	[28]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)	OTDRV63V	GA45A_HUMAN	Increases Expression	[39]
Cyclin-dependent kinase 2 (CDK2)	OTB5DYYZ	CDK2_HUMAN	Decreases Expression	[29]
DNA cytosine-5)-methyltransferase 1 (DNMT1)	OTM2DGTK	DNMT1_HUMAN	Decreases Expression	[40]
G1/S-specific cyclin-D2 (CCND2)	OTDULQF9	CCND2_HUMAN	Affects Methylation	[41]
Oxytocin receptor (OXTR)	OT7WFW4U	OXYR_HUMAN	Decreases Expression	[28]
Caspase-3 (CASP3)	OTIJRBE7	CASP3_HUMAN	Affects Expression	[15]
Cyclin-dependent kinase inhibitor 2A (CDKN2A)	OTN0ZWAE	CDN2A_HUMAN	Decreases Methylation	[42]
Melanoma-associated antigen 1 (MAGEA1)	OTXAO193	MAGA1_HUMAN	Decreases Methylation	[42]
Melanoma-associated antigen 3 (MAGEA3)	OTW3Y5M4	MAGA3_HUMAN	Increases Expression	[43]
Killer cell immunoglobulin-like receptor 2DL1 (KIR2DL1)	OTL1LBQJ	KI2L1_HUMAN	Increases Expression	[44]
Killer cell immunoglobulin-like receptor 2DL2 (KIR2DL2)	OTOVUTJD	KI2L2_HUMAN	Increases Expression	[44]
Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3)	OTFCN53B	KI2L3_HUMAN	Increases Expression	[44]
Killer cell immunoglobulin-like receptor 3DL1 (KIR3DL1)	OTPOSXFX	KI3L1_HUMAN	Increases Expression	[44]
Killer cell immunoglobulin-like receptor 2DS4 (KIR2DS4)	OT00N6UJ	KI2S4_HUMAN	Increases Expression	[44]
Tumor necrosis factor ligand superfamily member 6 (FASLG)	OTZARCHH	TNFL6_HUMAN	Increases Response To Substance	[24]
Stromal cell-derived factor 1 (CXCL12)	OT2QX5LL	SDF1_HUMAN	Increases Expression	[45]
Tuberin (TSC2)	OT47LWI9	TSC2_HUMAN	Increases Expression	[46]
Tumor necrosis factor ligand superfamily member 10 (TNFSF10)	OT4PXBTA	TNF10_HUMAN	Increases Response To Substance	[24]
High mobility group protein HMGI-C (HMGA2)	OTBMBHHL	HMGA2_HUMAN	Increases Expression	[28]
Homeobox protein Nkx-2.5 (NKX2-5)	OTS1SAWM	NKX25_HUMAN	Increases Expression	[47]
Death-associated protein kinase 1 (DAPK1)	OTNCNUCO	DAPK1_HUMAN	Affects Methylation	[48]
Claudin-6 (CLDN6)	OTEN8ID2	CLD6_HUMAN	Increases Expression	[22]
Claudin-8 (CLDN8)	OT7IIWXG	CLD8_HUMAN	Increases Expression	[22]
Small ribosomal subunit protein eS6 (RPS6)	OTT4D1LN	RS6_HUMAN	Decreases Phosphorylation	[28]
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA)	OT83PT85	PP2AA_HUMAN	Increases Expression	[49]
Cyclin-A1 (CCNA1)	OTX4HD45	CCNA1_HUMAN	Decreases Expression	[50]
Heat shock factor protein 1 (HSF1)	OTYNJ4KP	HSF1_HUMAN	Decreases Activity	[51]
Transcription factor p65 (RELA)	OTUJP9CN	TF65_HUMAN	Affects Localization	[15]
Tight junction protein ZO-1 (TJP1)	OTBDCUPK	ZO1_HUMAN	Increases Expression	[22]
Dihydropyrimidine dehydrogenase (DPYD)	OTWRF2NR	DPYD_HUMAN	Decreases Methylation	[52]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3)	OT4SO7J4	BNIP3_HUMAN	Increases Expression	[53]
N-myc-interactor (NMI)	OTYVG3NM	NMI_HUMAN	Increases Expression	[28]
NAD(P) transhydrogenase, mitochondrial (NNT)	OTAIOGZK	NNTM_HUMAN	Increases Expression	[21]
Runt-related transcription factor 3 (RUNX3)	OTITK1XD	RUNX3_HUMAN	Affects Methylation	[54]
Caspase-8 (CASP8)	OTA8TVI8	CASP8_HUMAN	Increases Expression	[55]
Cyclin-G2 (CCNG2)	OTII38K2	CCNG2_HUMAN	Decreases Expression	[28]
Occludin (OCLN)	OTSUTVWL	OCLN_HUMAN	Increases Expression	[22]
kinase isozyme 4, mitochondrial (PDK4)	OTCMHMBZ	PDK4_HUMAN	Decreases Methylation	[56]
Dual specificity protein phosphatase 6 (DUSP6)	OT4H6RKW	DUS6_HUMAN	Increases Expression	[28]
Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B)	OTE8GBUR	RIR2B_HUMAN	Increases Expression	[57]
Sodium/iodide cotransporter (SLC5A5)	OTU7E9G7	SC5A5_HUMAN	Increases Expression	[58]
Krueppel-like factor 6 (KLF6)	OTQY9S7F	KLF6_HUMAN	Increases Expression	[28]
Killer cell immunoglobulin-like receptor 2DL4 (KIR2DL4)	OTXN18OA	KI2L4_HUMAN	Increases Expression	[44]
Protein Niban 1 (NIBAN1)	OTYOLI12	NIBA1_HUMAN	Increases Expression	[28]
Calcium homeostasis modulator protein 2 (CALHM2)	OTWWM6HI	CAHM2_HUMAN	Increases Expression	[21]
Homeobox protein SIX2 (SIX2)	OTYOVGSC	SIX2_HUMAN	Decreases Expression	[21]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (PLCB1)	OT9HYT7A	PLCB1_HUMAN	Increases Expression	[59]
Sal-like protein 4 (SALL4)	OTC08PR5	SALL4_HUMAN	Affects Methylation	[11]
Transcription factor MafB (MAFB)	OTH2N3T8	MAFB_HUMAN	Increases Expression	[21]
Sodium/nucleoside cotransporter 1 (SLC28A1)	OTXWVV9O	S28A1_HUMAN	Increases Response To Substance	[60]

Indication(s) of Dasatinib

Disease Entry	ICD 11	Status	REF
Blast phase chronic myelogenous leukemia, BCR-ABL1 positive	N.A.	Approved	[4]
Brain disease	8C70-8E61	Approved	[4]
Central nervous system disease	8A04-8D87	Approved	[4]
Chronic myelogenous leukaemia	2A20.0	Approved	[5]
Chronic myeloid leukaemia	2A20	Approved	[6]
Glioblastoma	2A00	Approved	[4]
Leukemia	N.A.	Approved	[4]
Lung cancer	2C25.0	Approved	[4]
Non-small-cell lung cancer	2C25.Y	Approved	[4]
Plasma cell myeloma	2A83.1	Approved	[4]
Multiple myeloma	2A83	Phase 2	[5]
Middle East Respiratory Syndrome (MERS)	1D64	Investigative	[7]
Severe acute respiratory syndrome (SARS)	1D65	Investigative	[7]

Dasatinib Interacts with 5 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
LCK tyrosine protein kinase (LCK)	TT860QF	LCK_HUMAN	Inhibitor	[64]
Fyn tyrosine protein kinase (FYN)	TT2B9KF	FYN_HUMAN	Inhibitor	[64]
Fusion protein Bcr-Abl (Bcr-Abl)	TTS7G69	BCR_HUMAN-ABL1_HUMAN	Inhibitor	[64]
Proto-oncogene c-Src (SRC)	TT6PKBN	SRC_HUMAN	Inhibitor	[64]
HUMAN fusion protein Bcr-Abl (Bcr-Abl)	TTE63HY	BCR_HUMAN/ABL1_HUMAN	Inhibitor	[7]

Dasatinib Interacts with 4 DTP Molecule(s)

DTP Name	DTP ID	UniProt ID	Mode of Action	REF
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[65]
Breast cancer resistance protein (ABCG2)	DTI7UX6	ABCG2_HUMAN	Substrate	[66]
Organic anion transporting polypeptide 1B1 (SLCO1B1)	DT3D8F0	SO1B1_HUMAN	Substrate	[67]
Organic anion transporting polypeptide 1B3 (SLCO1B3)	DT9C1TS	SO1B3_HUMAN	Substrate	[67]

Dasatinib Interacts with 4 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Cytochrome P450 3A4 (CYP3A4)	DE4LYSA	CP3A4_HUMAN	Metabolism	[68]
Cytochrome P450 1A2 (CYP1A2)	DEJGDUW	CP1A2_HUMAN	Metabolism	[68]
Cytochrome P450 3A5 (CYP3A5)	DEIBDNY	CP3A5_HUMAN	Metabolism	[68]
Dimethylaniline oxidase 3 (FMO3)	DEP76YL	FMO3_HUMAN	Metabolism	[69]

Dasatinib Interacts with 453 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
Tyrosine-protein kinase Fyn (FYN)	OTLSLVZS	FYN_HUMAN	Affects Binding	[61]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3)	OTB6YLFT	ENPP3_HUMAN	Decreases Expression	[61]
Tyrosine-protein kinase HCK (HCK)	OTRL6OSI	HCK_HUMAN	Decreases Phosphorylation	[61]
CD63 antigen (CD63)	OT2UGZA9	CD63_HUMAN	Decreases Expression	[61]
Tyrosine-protein kinase Fgr (FGR)	OTCUYU9F	FGR_HUMAN	Affects Binding	[61]
Heat shock cognate 71 kDa protein (HSPA8)	OTJI2RCI	HSP7C_HUMAN	Affects Binding	[61]
Aminopeptidase N (ANPEP)	OTP3WYFD	AMPN_HUMAN	Decreases Expression	[61]
Tyrosine-protein kinase CSK (CSK)	OTP03OD0	CSK_HUMAN	Affects Binding	[61]
Tyrosine-protein kinase Tec (TEC)	OTU6QJAJ	TEC_HUMAN	Affects Binding	[61]
Tyrosine-protein kinase FRK (FRK)	OTEKV1SC	FRK_HUMAN	Affects Binding	[61]
Ephrin type-A receptor 5 (EPHA5)	OTAM0CVX	EPHA5_HUMAN	Affects Binding	[61]
Ephrin type-B receptor 4 (EPHB4)	OTKLPVXJ	EPHB4_HUMAN	Affects Binding	[61]
Sialomucin core protein 24 (CD164)	OTZ7FIU8	MUC24_HUMAN	Decreases Expression	[61]
Amidophosphoribosyltransferase (PPAT)	OTXK12ZB	PUR1_HUMAN	Affects Binding	[61]
Mitogen-activated protein kinase 14 (MAPK14)	OT5TCO3O	MK14_HUMAN	Affects Binding	[61]
Mitogen-activated protein kinase kinase kinase 20 (MAP3K20)	OT0ALMEG	M3K20_HUMAN	Affects Binding	[61]
ATP-dependent RNA helicase DDX39A (DDX39A)	OT0Z6E1K	DX39A_HUMAN	Decreases Expression	[62]
Cell division cycle 7-related protein kinase (CDC7)	OT5133XY	CDC7_HUMAN	Decreases Expression	[62]
Serine/threonine-protein kinase PLK4 (PLK4)	OTV8KZDZ	PLK4_HUMAN	Decreases Expression	[62]
Nuclear envelope integral membrane protein 1 (NEMP1)	OTWN3S47	NEMP1_HUMAN	Decreases Expression	[62]
Kinetochore protein NDC80 homolog (NDC80)	OTS7D306	NDC80_HUMAN	Decreases Expression	[62]
Aurora kinase A (AURKA)	OTMX0HYT	AURKA_HUMAN	Decreases Expression	[62]
DNA-directed RNA polymerase III subunit RPC7 (POLR3G)	OTU3TGQ9	RPC7_HUMAN	Decreases Expression	[62]
Fanconi anemia group A protein (FANCA)	OTPEFJD4	FANCA_HUMAN	Decreases Expression	[62]
Baculoviral IAP repeat-containing protein 5 (BIRC5)	OTILXZYL	BIRC5_HUMAN	Decreases Expression	[62]
Monocarboxylate transporter 7 (SLC16A6)	OT7BIIZX	MOT7_HUMAN	Decreases Expression	[62]
ATP-binding cassette sub-family C member 3 (ABCC3)	OTC3IJV4	MRP3_HUMAN	Increases Expression	[62]
Protein sprouty homolog 2 (SPRY2)	OTH0CRCZ	SPY2_HUMAN	Decreases Expression	[62]
Protein regulator of cytokinesis 1 (PRC1)	OTHD0XS0	PRC1_HUMAN	Decreases Expression	[62]
Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1)	OT80DZMT	BUB1_HUMAN	Decreases Expression	[62]
EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3)	OTDVVNS0	EDIL3_HUMAN	Increases Expression	[62]
NUAK family SNF1-like kinase 1 (NUAK1)	OTLLHJJQ	NUAK1_HUMAN	Increases Expression	[62]
Neuropilin-2 (NRP2)	OTZL256E	NRP2_HUMAN	Increases Expression	[62]
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B)	OT8KME51	BUB1B_HUMAN	Decreases Expression	[62]
Tetraspanin-2 (TSPAN2)	OTTDPQF1	TSN2_HUMAN	Increases Expression	[62]
Leupaxin (LPXN)	OTUNV3CK	LPXN_HUMAN	Decreases Expression	[62]
Hyaluronan mediated motility receptor (HMMR)	OT4M0JTZ	HMMR_HUMAN	Decreases Expression	[62]
DNA polymerase theta (POLQ)	OTBHK0E6	DPOLQ_HUMAN	Decreases Expression	[62]
Cell division control protein 45 homolog (CDC45)	OT6NNLOD	CDC45_HUMAN	Decreases Expression	[62]
Glypican-4 (GPC4)	OTUJ14DW	GPC4_HUMAN	Increases Expression	[62]
Serpin B7 (SERPINB7)	OTZ95LR2	SPB7_HUMAN	Decreases Expression	[62]
Transient receptor potential cation channel subfamily A member 1 (TRPA1)	OTRDIR5M	TRPA1_HUMAN	Decreases Expression	[62]
Ribonuclease H2 subunit A (RNASEH2A)	OT8G3G7K	RNH2A_HUMAN	Decreases Expression	[62]
Short-chain dehydrogenase/reductase 3 (DHRS3)	OTSK1DTP	DHRS3_HUMAN	Increases Expression	[62]
Dickkopf-related protein 1 (DKK1)	OTRDLUSP	DKK1_HUMAN	Decreases Expression	[62]
Centrosomal protein of 152 kDa (CEP152)	OTOKZR9B	CE152_HUMAN	Decreases Expression	[62]
Potassium channel subfamily K member 2 (KCNK2)	OTWBT8MG	KCNK2_HUMAN	Decreases Expression	[62]
Chromosome-associated kinesin KIF4A (KIF4A)	OT3UWL7D	KIF4A_HUMAN	Decreases Expression	[62]
Structural maintenance of chromosomes protein 2 (SMC2)	OT5S0DV4	SMC2_HUMAN	Decreases Expression	[62]
Phospholipid-transporting ATPase ABCA1 (ABCA1)	OT94G6BQ	ABCA1_HUMAN	Increases Expression	[62]
Reversion-inducing cysteine-rich protein with Kazal motifs (RECK)	OT9QIHEQ	RECK_HUMAN	Increases Expression	[62]
Securin (PTTG1)	OTIMYS4W	PTTG1_HUMAN	Decreases Expression	[62]
Histone-lysine N-methyltransferase NSD2 (NSD2)	OTQ6SW4R	NSD2_HUMAN	Decreases Expression	[62]
Aldehyde dehydrogenase 1A1 (ALDH1A1)	OTCUWZKB	AL1A1_HUMAN	Increases Expression	[62]
Dihydrofolate reductase (DHFR)	OT3DVIGM	DYR_HUMAN	Decreases Expression	[62]
Complement C1r subcomponent (C1R)	OTA0ZNIU	C1R_HUMAN	Increases Expression	[62]
Urokinase-type plasminogen activator (PLAU)	OTX0QGKK	UROK_HUMAN	Decreases Expression	[62]
Alpha-2-macroglobulin (A2M)	OTFTX90K	A2MG_HUMAN	Increases Expression	[62]
Insulin-like growth factor II (IGF2)	OTJ4O6MW	IGF2_HUMAN	Increases Expression	[62]
Collagen alpha-1(III) chain (COL3A1)	OTT1EMLM	CO3A1_HUMAN	Increases Expression	[62]
Collagen alpha-1(IV) chain (COL4A1)	OTL6D1YE	CO4A1_HUMAN	Increases Expression	[62]
Alpha-crystallin B chain (CRYAB)	OTY4JGYU	CRYAB_HUMAN	Increases Expression	[62]
Interstitial collagenase (MMP1)	OTI4I2V1	MMP1_HUMAN	Decreases Expression	[62]
Thymidine kinase, cytosolic (TK1)	OTY5JFM1	KITH_HUMAN	Decreases Expression	[62]
Aldehyde dehydrogenase, mitochondrial (ALDH2)	OTKJ9I3N	ALDH2_HUMAN	Increases Expression	[62]
Plasminogen activator inhibitor 2 (SERPINB2)	OT72QLZB	PAI2_HUMAN	Decreases Expression	[62]
Interleukin-6 (IL6)	OTUOSCCU	IL6_HUMAN	Increases Expression	[62]
Cyclin-dependent kinase 1 (CDK1)	OTW1SC2N	CDK1_HUMAN	Decreases Expression	[62]
Integrin alpha-V (ITGAV)	OTAM7JTR	ITAV_HUMAN	Increases Expression	[62]
Epoxide hydrolase 1 (EPHX1)	OTBKWQER	HYEP_HUMAN	Increases Expression	[62]
Neurofilament medium polypeptide (NEFM)	OT8VCBNF	NFM_HUMAN	Decreases Expression	[62]
Laminin subunit beta-1 (LAMB1)	OT6J9LJR	LAMB1_HUMAN	Increases Expression	[62]
Asparagine synthetase (ASNS)	OT8R922G	ASNS_HUMAN	Increases Expression	[62]
Matrix Gla protein (MGP)	OTZWU3FU	MGP_HUMAN	Increases Expression	[62]
Collagen alpha-2(IV) chain (COL4A2)	OTJK1LKN	CO4A2_HUMAN	Increases Expression	[62]
Platelet-derived growth factor receptor beta (PDGFRB)	OTYSNK9Q	PGFRB_HUMAN	Increases Expression	[62]
Complement C1s subcomponent (C1S)	OTCIZU2A	C1S_HUMAN	Increases Expression	[62]
DNA polymerase alpha catalytic subunit (POLA1)	OT1WXFVY	DPOLA_HUMAN	Decreases Expression	[62]
Histone H2A.Z (H2AZ1)	OT3KJJNQ	H2AZ_HUMAN	Decreases Expression	[62]
Myb-related protein A (MYBL1)	OTBJMC2P	MYBA_HUMAN	Decreases Expression	[62]
Myb-related protein B (MYBL2)	OTZ3JX8Q	MYBB_HUMAN	Decreases Expression	[62]
Histone H1.4 (H1-4)	OTQ450A3	H14_HUMAN	Decreases Expression	[62]
Clusterin (CLU)	OTQGG0JM	CLUS_HUMAN	Increases Expression	[62]
DNA topoisomerase 2-alpha (TOP2A)	OT6LPS08	TOP2A_HUMAN	Decreases Expression	[62]
Fibroblast growth factor 5 (FGF5)	OTQXGHBY	FGF5_HUMAN	Decreases Expression	[62]
Collagen alpha-1(XI) chain (COL11A1)	OTB0DRMS	COBA1_HUMAN	Increases Expression	[62]
Elastin (ELN)	OTFSO7PG	ELN_HUMAN	Increases Expression	[62]
Aggrecan core protein (ACAN)	OTUOCW8K	PGCA_HUMAN	Increases Expression	[62]
Histone H1.5 (H1-5)	OTAN7RD9	H15_HUMAN	Decreases Expression	[62]
Stathmin (STMN1)	OTDJ4RV0	STMN1_HUMAN	Decreases Expression	[62]
Lamin-B1 (LMNB1)	OT100T3P	LMNB1_HUMAN	Decreases Expression	[62]
Biglycan (BGN)	OT3AV6IF	PGS1_HUMAN	Increases Expression	[62]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1)	OT3MPPYX	ENPP1_HUMAN	Decreases Expression	[62]
Liver carboxylesterase 1 (CES1)	OT9L0LR8	EST1_HUMAN	Increases Expression	[62]
Integrin alpha-6 (ITGA6)	OT3FA39C	ITA6_HUMAN	Decreases Expression	[62]
Ribonucleoside-diphosphate reductase large subunit (RRM1)	OTXGQOR9	RIR1_HUMAN	Decreases Expression	[62]
Insulin-like growth factor-binding protein 5 (IGFBP5)	OTRE5V0C	IBP5_HUMAN	Increases Expression	[62]
Cyclin-dependent kinase 2 (CDK2)	OTB5DYYZ	CDK2_HUMAN	Decreases Expression	[62]
Pentraxin-related protein PTX3 (PTX3)	OTPXHRKU	PTX3_HUMAN	Decreases Expression	[62]
High mobility group protein B2 (HMGB2)	OTGEGAOK	HMGB2_HUMAN	Decreases Expression	[62]
Cardiac phospholamban (PLN)	OTT3RRJN	PPLA_HUMAN	Increases Expression	[62]
G0/G1 switch protein 2 (G0S2)	OT8FL49L	G0S2_HUMAN	Decreases Expression	[62]
Dipeptidyl peptidase 4 (DPP4)	OT16MVL9	DPP4_HUMAN	Increases Expression	[62]
Leiomodin-1 (LMOD1)	OTZ2MEMG	LMOD1_HUMAN	Increases Expression	[62]
M-phase inducer phosphatase 1 (CDC25A)	OTSLKKCO	MPIP1_HUMAN	Decreases Expression	[62]
M-phase inducer phosphatase 3 (CDC25C)	OTPQI71S	MPIP3_HUMAN	Decreases Expression	[62]
Ribonucleoside-diphosphate reductase subunit M2 (RRM2)	OTOB6J6R	RIR2_HUMAN	Decreases Expression	[62]
Fibroblast growth factor 9 (FGF9)	OT2SKDGM	FGF9_HUMAN	Increases Expression	[62]
Sodium- and chloride-dependent taurine transporter (SLC6A6)	OT67U7G3	SC6A6_HUMAN	Increases Expression	[62]
Cyclin-dependent kinases regulatory subunit 2 (CKS2)	OTPTMHIV	CKS2_HUMAN	Decreases Expression	[62]
Histone H2B type 1-B (H2BC3)	OT1BLFJO	H2B1B_HUMAN	Decreases Expression	[62]
Dual specificity protein kinase TTK (TTK)	OTBY1Z5H	TTK_HUMAN	Decreases Expression	[62]
DNA replication licensing factor MCM7 (MCM7)	OT6FXC6K	MCM7_HUMAN	Decreases Expression	[62]
Syndecan-2 (SDC2)	OTEEHY1D	SDC2_HUMAN	Increases Expression	[62]
Replication factor C subunit 4 (RFC4)	OTWALD2R	RFC4_HUMAN	Decreases Expression	[62]
Replication factor C subunit 2 (RFC2)	OTJ9N6BD	RFC2_HUMAN	Decreases Expression	[62]
Thrombospondin-2 (THBS2)	OTXET551	TSP2_HUMAN	Increases Expression	[62]
Myosin-10 (MYH10)	OTXN2WXS	MYH10_HUMAN	Increases Expression	[62]
Myosin-11 (MYH11)	OTVNVWY3	MYH11_HUMAN	Increases Expression	[62]
Chitinase-3-like protein 1 (CHI3L1)	OT2Z7VJH	CH3L1_HUMAN	Increases Expression	[62]
Breast cancer type 1 susceptibility protein (BRCA1)	OT5BN6VH	BRCA1_HUMAN	Decreases Expression	[62]
Flap endonuclease 1 (FEN1)	OT6QGG7O	FEN1_HUMAN	Decreases Expression	[62]
Nicotinamide N-methyltransferase (NNMT)	OTFM38GU	NNMT_HUMAN	Increases Expression	[62]
Pre-B-cell leukemia transcription factor 1 (PBX1)	OTORABGO	PBX1_HUMAN	Increases Expression	[62]
Replication factor C subunit 5 (RFC5)	OTAD79RT	RFC5_HUMAN	Decreases Expression	[62]
Replication factor C subunit 3 (RFC3)	OT1MS7AO	RFC3_HUMAN	Decreases Expression	[62]
5-hydroxytryptamine receptor 2B (HTR2B)	OTM1AD9J	5HT2B_HUMAN	Increases Expression	[62]
Lamina-associated polypeptide 2, isoform alpha (TMPO)	OTL68EL4	LAP2A_HUMAN	Decreases Expression	[62]
Aldo-keto reductase family 1 member C3 (AKR1C3)	OTU2SXBA	AK1C3_HUMAN	Increases Expression	[62]
Condensin-2 complex subunit D3 (NCAPD3)	OTOZY2UL	CNDD3_HUMAN	Decreases Expression	[62]
Neutral amino acid transporter A (SLC1A4)	OTVODHAE	SATT_HUMAN	Increases Expression	[62]
Cell surface glycoprotein MUC18 (MCAM)	OTT8XKGE	MUC18_HUMAN	Increases Expression	[62]
DNA mismatch repair protein Msh2 (MSH2)	OT10H1AB	MSH2_HUMAN	Decreases Expression	[62]
Proliferation marker protein Ki-67 (MKI67)	OTA8N1QI	KI67_HUMAN	Decreases Expression	[62]
Glutathione S-transferase Mu 5 (GSTM5)	OTMMBFY8	GSTM5_HUMAN	Increases Expression	[62]
Histone H3-like centromeric protein A (CENPA)	OT0NEJ4X	CENPA_HUMAN	Decreases Expression	[62]
Centromere protein F (CENPF)	OT7AG0SW	CENPF_HUMAN	Decreases Expression	[62]
DNA primase small subunit (PRIM1)	OTWWP8Y6	PRI1_HUMAN	Decreases Expression	[62]
DNA primase large subunit (PRIM2)	OTGT0KTF	PRI2_HUMAN	Decreases Expression	[62]
Thrombospondin-3 (THBS3)	OTDKMUBD	TSP3_HUMAN	Increases Expression	[62]
Regulator of G-protein signaling 4 (RGS4)	OTG94HHL	RGS4_HUMAN	Decreases Expression	[62]
Selenoprotein P (SELENOP)	OT02B8IR	SEPP1_HUMAN	Increases Expression	[62]
Kinetochore-associated protein 1 (KNTC1)	OTI2OOFN	KNTC1_HUMAN	Decreases Expression	[62]
Ras association domain-containing protein 2 (RASSF2)	OT2JHDO4	RASF2_HUMAN	Increases Expression	[62]
DNA replication ATP-dependent helicase/nuclease DNA2 (DNA2)	OT4DJFFU	DNA2_HUMAN	Decreases Expression	[62]
Breast cancer type 2 susceptibility protein (BRCA2)	OTF1XSV1	BRCA2_HUMAN	Decreases Expression	[62]
Lumican (LUM)	OTSRC874	LUM_HUMAN	Increases Expression	[62]
Calponin-1 (CNN1)	OTVPG39Z	CNN1_HUMAN	Increases Expression	[62]
Importin subunit alpha-1 (KPNA2)	OTU7FOE6	IMA1_HUMAN	Decreases Expression	[62]
Stanniocalcin-1 (STC1)	OTGVVXYF	STC1_HUMAN	Decreases Expression	[62]
High mobility group protein HMGI-C (HMGA2)	OTBMBHHL	HMGA2_HUMAN	Decreases Expression	[62]
Serine/threonine-protein kinase PLK1 (PLK1)	OTRZX45T	PLK1_HUMAN	Decreases Expression	[62]
Microfibril-associated glycoprotein 4 (MFAP4)	OT5W64QY	MFAP4_HUMAN	Increases Expression	[62]
DNA polymerase epsilon subunit 2 (POLE2)	OTAC9V6L	DPOE2_HUMAN	Decreases Expression	[62]
Cyclin-dependent kinases regulatory subunit 1 (CKS1B)	OTNUPLUJ	CKS1_HUMAN	Decreases Expression	[62]
Transforming growth factor beta-2 proprotein (TGFB2)	OTC0TXEP	TGFB2_HUMAN	Increases Expression	[62]
Actin, aortic smooth muscle (ACTA2)	OTEDLG8E	ACTA_HUMAN	Increases Expression	[62]
Actin, gamma-enteric smooth muscle (ACTG2)	OTRDWUO0	ACTH_HUMAN	Increases Expression	[62]
Actin, alpha cardiac muscle 1 (ACTC1)	OTJU04B1	ACTC_HUMAN	Increases Expression	[62]
Protein jagged-1 (JAG1)	OT3LGT6K	JAG1_HUMAN	Increases Expression	[62]
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1)	OTEUYEW6	ROR1_HUMAN	Increases Expression	[62]
Centromere-associated protein E (CENPE)	OTQ7AP04	CENPE_HUMAN	Decreases Expression	[62]
Kinesin-like protein KIF23 (KIF23)	OTY850JC	KIF23_HUMAN	Decreases Expression	[62]
Histone H1.1 (H1-1)	OTSS815G	H11_HUMAN	Decreases Expression	[62]
Aldehyde oxidase (AOX1)	OT2FZP6H	AOXA_HUMAN	Decreases Expression	[62]
DNA repair protein RAD51 homolog 1 (RAD51)	OTNVWGC1	RAD51_HUMAN	Decreases Expression	[62]
Transcription factor SOX-4 (SOX4)	OTSS40SS	SOX4_HUMAN	Increases Expression	[62]
Prolow-density lipoprotein receptor-related protein 1 (LRP1)	OTHTEH4G	LRP1_HUMAN	Increases Expression	[62]
Forkhead box protein M1 (FOXM1)	OT5887KR	FOXM1_HUMAN	Decreases Expression	[62]
Lactadherin (MFGE8)	OTQKE41R	MFGM_HUMAN	Increases Expression	[62]
EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1)	OTZVUOOB	FBLN3_HUMAN	Increases Expression	[62]
Cell division cycle protein 20 homolog (CDC20)	OTCOEZRV	CDC20_HUMAN	Decreases Expression	[62]
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1)	OTA0UNHM	ECH1_HUMAN	Increases Expression	[62]
MAL-like protein (MALL)	OTKGZ89D	MALL_HUMAN	Decreases Expression	[62]
Mitotic spindle assembly checkpoint protein MAD2A (MAD2L1)	OTXNGZCG	MD2L1_HUMAN	Decreases Expression	[62]
Centromere protein R (ITGB3BP)	OT6Q7GR3	CENPR_HUMAN	Decreases Expression	[62]
Origin recognition complex subunit 1 (ORC1)	OTHWU8IJ	ORC1_HUMAN	Decreases Expression	[62]
Limbic system-associated membrane protein (LSAMP)	OTYXVQX2	LSAMP_HUMAN	Increases Expression	[62]
Four and a half LIM domains protein 1 (FHL1)	OTN535SU	FHL1_HUMAN	Increases Expression	[62]
Voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C)	OT6KFNMS	CAC1C_HUMAN	Increases Expression	[62]
DNA polymerase alpha subunit B (POLA2)	OTTWQ73N	DPOA2_HUMAN	Decreases Expression	[62]
Fibroleukin (FGL2)	OT8M3H72	FGL2_HUMAN	Increases Expression	[62]
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (PDE3A)	OTKUW1WT	PDE3A_HUMAN	Increases Expression	[62]
Semaphorin-3A (SEMA3A)	OTQJSV7W	SEM3A_HUMAN	Decreases Expression	[62]
DNA replication licensing factor MCM6 (MCM6)	OTKLIAWT	MCM6_HUMAN	Decreases Expression	[62]
Inositol 1,4,5-trisphosphate receptor type 1 (ITPR1)	OTX7MWW1	ITPR1_HUMAN	Increases Expression	[62]
Maternal embryonic leucine zipper kinase (MELK)	OTEY2UQA	MELK_HUMAN	Decreases Expression	[62]
DNA replication complex GINS protein PSF1 (GINS1)	OTVQZMMQ	PSF1_HUMAN	Decreases Expression	[62]
Transmembrane glycoprotein NMB (GPNMB)	OTB7KQKV	GPNMB_HUMAN	Increases Expression	[62]
Condensin complex subunit 2 (NCAPH)	OTXOS97C	CND2_HUMAN	Decreases Expression	[62]
PCNA-associated factor (PCLAF)	OTMVIOUU	PAF15_HUMAN	Decreases Expression	[62]
Condensin complex subunit 1 (NCAPD2)	OT8VGE2O	CND1_HUMAN	Decreases Expression	[62]
Disks large-associated protein 5 (DLGAP5)	OTWCN39U	DLGP5_HUMAN	Decreases Expression	[62]
SCL-interrupting locus protein (STIL)	OT9799VN	STIL_HUMAN	Decreases Expression	[62]
Pachytene checkpoint protein 2 homolog (TRIP13)	OTFM3TI9	PCH2_HUMAN	Decreases Expression	[62]
Myosin light chain kinase, smooth muscle (MYLK)	OT78QB4A	MYLK_HUMAN	Increases Expression	[62]
Histone-lysine N-methyltransferase EZH2 (EZH2)	OTIEHTKW	EZH2_HUMAN	Decreases Expression	[62]
Insulin-like growth factor-binding protein 7 (IGFBP7)	OT1D416P	IBP7_HUMAN	Increases Expression	[62]
Neuronal regeneration-related protein (NREP)	OT2AZPKK	NREP_HUMAN	Increases Expression	[62]
Prostacyclin synthase (PTGIS)	OTT3RW6N	PTGIS_HUMAN	Increases Expression	[62]
Cyclin-dependent kinase inhibitor 3 (CDKN3)	OTBE3H07	CDKN3_HUMAN	Decreases Expression	[62]
Cytochrome P450 1B1 (CYP1B1)	OTYXFLSD	CP1B1_HUMAN	Increases Expression	[62]
Phosphoenolpyruvate carboxykinase , mitochondrial (PCK2)	OTJ8LX4N	PCKGM_HUMAN	Increases Expression	[62]
Tumor protein D53 (TPD52L1)	OTSA6U0I	TPD53_HUMAN	Increases Expression	[62]
Flap endonuclease GEN homolog 1 (GEN1)	OT1XFQXF	GEN_HUMAN	Decreases Expression	[62]
Mitochondrial 10-formyltetrahydrofolate dehydrogenase (ALDH1L2)	OTCH86VF	AL1L2_HUMAN	Increases Expression	[62]
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (SVEP1)	OTOBICRD	SVEP1_HUMAN	Increases Expression	[62]
Borealin (CDCA8)	OT17D55D	BOREA_HUMAN	Decreases Expression	[62]
Protein LBH (LBH)	OT87AT1X	LBH_HUMAN	Increases Expression	[62]
Shugoshin 2 (SGO2)	OTNGJDS8	SGO2_HUMAN	Decreases Expression	[62]
Centromere protein W (CENPW)	OTZL05QN	CENPW_HUMAN	Decreases Expression	[62]
Shugoshin 1 (SGO1)	OTIP6IRN	SGO1_HUMAN	Decreases Expression	[62]
Probable E3 ubiquitin-protein ligase HERC4 (HERC4)	OTU4DSDE	HERC4_HUMAN	Decreases Expression	[62]
Testis-expressed protein 30 (TEX30)	OT87WEPQ	TEX30_HUMAN	Decreases Expression	[62]
DEP domain-containing protein 1A (DEPDC1)	OT0JWE1B	DEP1A_HUMAN	Decreases Expression	[62]
Tensin-3 (TNS3)	OTPG2D8Z	TENS3_HUMAN	Increases Expression	[62]
Cell division cycle-associated protein 2 (CDCA2)	OTX8UF9J	CDCA2_HUMAN	Decreases Expression	[62]
Protein FAM72D (FAM72D)	OTCQVOXB	FA72D_HUMAN	Decreases Expression	[62]
Repulsive guidance molecule B (RGMB)	OT2DROYU	RGMB_HUMAN	Decreases Expression	[62]
STEAP family member 1B (STEAP1B)	OTZJDFWK	STEAL_HUMAN	Decreases Expression	[62]
Mis18-binding protein 1 (MIS18BP1)	OT41T0FB	M18BP_HUMAN	Decreases Expression	[62]
Mitochondrial fission regulator 2 (MTFR2)	OTLOR68D	MTFR2_HUMAN	Decreases Expression	[62]
Rho GTPase-activating protein 11A (ARHGAP11A)	OTVQCFVP	RHGBA_HUMAN	Decreases Expression	[62]
E3 ubiquitin-protein ligase RFWD3 (RFWD3)	OTDUULBQ	RFWD3_HUMAN	Decreases Expression	[62]
Podocan-like protein 1 (PODNL1)	OTL72ES9	PONL1_HUMAN	Increases Expression	[62]
Protein aurora borealis (BORA)	OTV2ZPKP	BORA_HUMAN	Decreases Expression	[62]
Neutral cholesterol ester hydrolase 1 (NCEH1)	OTZ66CKX	NCEH1_HUMAN	Decreases Expression	[62]
Fidgetin-like protein 1 (FIGNL1)	OTKII63K	FIGL1_HUMAN	Decreases Expression	[62]
ATPase family AAA domain-containing protein 2 (ATAD2)	OT8MCRNY	ATAD2_HUMAN	Decreases Expression	[62]
Serine protease FAM111B (FAM111B)	OT9IQ9NV	F111B_HUMAN	Decreases Expression	[62]
Protein FAM180A (FAM180A)	OTKQ7XUG	F180A_HUMAN	Decreases Expression	[62]
Golgi-associated kinase 1B (GASK1B)	OT2HPHEI	GAK1B_HUMAN	Increases Expression	[62]
Plexin domain-containing protein 2 (PLXDC2)	OTS1FUV6	PXDC2_HUMAN	Increases Expression	[62]
ALK and LTK ligand 1 (ALKAL1)	OTZGAZ79	ALKL1_HUMAN	Increases Expression	[62]
Protein MMS22-like (MMS22L)	OTJI0HM9	MMS22_HUMAN	Decreases Expression	[62]
Centrosomal protein of 128 kDa (CEP128)	OT922YCJ	CE128_HUMAN	Decreases Expression	[62]
DNA-binding protein RFX8 (RFX8)	OT27SFGQ	RFX8_HUMAN	Decreases Expression	[62]
Centromere protein U (CENPU)	OTQ4TZRS	CENPU_HUMAN	Decreases Expression	[62]
Protein MCM10 homolog (MCM10)	OTV0O3JN	MCM10_HUMAN	Decreases Expression	[62]
Treslin (TICRR)	OT2HKWOC	TICRR_HUMAN	Decreases Expression	[62]
MAM domain-containing protein 2 (MAMDC2)	OT4GICNY	MAMC2_HUMAN	Increases Expression	[62]
LisH domain-containing protein ARMC9 (ARMC9)	OT0MZER2	ARMC9_HUMAN	Increases Expression	[62]
Rho GTPase-activating protein 22 (ARHGAP22)	OTXUQEFL	RHG22_HUMAN	Decreases Expression	[62]
Podocan (PODN)	OTV3P7P5	PODN_HUMAN	Increases Expression	[62]
Schlafen family member 11 (SLFN11)	OTJWFPMY	SLN11_HUMAN	Decreases Expression	[62]
Amphoterin-induced protein 2 (AMIGO2)	OTPAIT1O	AMGO2_HUMAN	Increases Expression	[62]
Alpha-protein kinase 2 (ALPK2)	OTWZZDQ9	ALPK2_HUMAN	Increases Expression	[62]
Myopalladin (MYPN)	OTHTOFDU	MYPN_HUMAN	Decreases Expression	[62]
E3 ubiquitin-protein ligase MARCHF3 (MARCHF3)	OT89V4N5	MARH3_HUMAN	Decreases Expression	[62]
Ras GTPase-activating-like protein IQGAP3 (IQGAP3)	OT4RZV2M	IQGA3_HUMAN	Decreases Expression	[62]
Condensin-2 complex subunit G2 (NCAPG2)	OTZYENKO	CNDG2_HUMAN	Decreases Expression	[62]
GAS2-like protein 3 (GAS2L3)	OTWPVI29	GA2L3_HUMAN	Decreases Expression	[62]
Histone H2A type 2-B (H2AC21)	OTH7W2NJ	H2A2B_HUMAN	Decreases Expression	[62]
Pleckstrin homology domain-containing family H member 2 (PLEKHH2)	OT3TK3NN	PKHH2_HUMAN	Increases Expression	[62]
Extracellular sulfatase Sulf-2 (SULF2)	OTIXMUVL	SULF2_HUMAN	Increases Expression	[62]
Extracellular sulfatase Sulf-1 (SULF1)	OTJCNCO0	SULF1_HUMAN	Increases Expression	[62]
CD302 antigen (CD302)	OTX580VU	CD302_HUMAN	Increases Expression	[62]
Spindle and kinetochore-associated protein 3 (SKA3)	OTLHEVJD	SKA3_HUMAN	Decreases Expression	[62]
DNA damage-induced apoptosis suppressor protein (DDIAS)	OTTGG2PM	DDIAS_HUMAN	Decreases Expression	[62]
Cytoskeleton-associated protein 2-like (CKAP2L)	OT4T73GG	CKP2L_HUMAN	Decreases Expression	[62]
Fanconi anemia group M protein (FANCM)	OTNJG99Z	FANCM_HUMAN	Decreases Expression	[62]
Lung adenoma susceptibility protein 2 (C18ORF54)	OT4WJKTF	LAS2_HUMAN	Decreases Expression	[62]
Abnormal spindle-like microcephaly-associated protein (ASPM)	OTKXQMNA	ASPM_HUMAN	Decreases Expression	[62]
Retinol dehydrogenase 10 (RDH10)	OTL9FSGF	RDH10_HUMAN	Increases Expression	[62]
Centromere protein L (CENPL)	OT7P006B	CENPL_HUMAN	Decreases Expression	[62]
Rho GTPase-activating protein 18 (ARHGAP18)	OTYMJP6H	RHG18_HUMAN	Decreases Expression	[62]
T-complex protein 11-like protein 2 (TCP11L2)	OTTIZO7B	T11L2_HUMAN	Increases Expression	[62]
Aminopeptidase O (AOPEP)	OT0MMANL	AMPO_HUMAN	Increases Expression	[62]
Junction-mediating and -regulatory protein (JMY)	OTH5FFVK	JMY_HUMAN	Increases Expression	[62]
Holliday junction recognition protein (HJURP)	OTWMV16B	HJURP_HUMAN	Decreases Expression	[62]
SHC SH2 domain-binding protein 1 (SHCBP1)	OT3A21CM	SHCBP_HUMAN	Decreases Expression	[62]
MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (MDGA1)	OTVXEF85	MDGA1_HUMAN	Increases Expression	[62]
(Lyso)-N-acylphosphatidylethanolamine lipase (ABHD4)	OTQK3M9X	ABHD4_HUMAN	Increases Expression	[62]
DEP domain-containing mTOR-interacting protein (DEPTOR)	OTCBP1BT	DPTOR_HUMAN	Increases Expression	[62]
Protein CIP2A (CIP2A)	OTVS2GXA	CIP2A_HUMAN	Decreases Expression	[62]
Sodium-dependent phosphate transporter 1 (SLC20A1)	OTC3D894	S20A1_HUMAN	Decreases Expression	[62]
DEP domain-containing protein 1B (DEPDC1B)	OTMVFOT1	DEP1B_HUMAN	Decreases Expression	[62]
Basic helix-loop-helix ARNT-like protein 2 (BMAL2)	OTIBDGQC	BMAL2_HUMAN	Decreases Expression	[62]
Centromere protein I (CENPI)	OTWRIMZ3	CENPI_HUMAN	Decreases Expression	[62]
Serine protease HTRA1 (HTRA1)	OTR8ACBF	HTRA1_HUMAN	Increases Expression	[62]
Hyaluronan synthase 2 (HAS2)	OTTD3PAL	HYAS2_HUMAN	Decreases Expression	[62]
Neogenin (NEO1)	OTGJ1997	NEO1_HUMAN	Increases Expression	[62]
Histone H2B type 1-H (H2BC9)	OTQ9XX72	H2B1H_HUMAN	Decreases Expression	[62]
F-box only protein 32 (FBXO32)	OTUE978R	FBX32_HUMAN	Increases Expression	[62]
Tumor protein p53-inducible nuclear protein 1 (TP53INP1)	OT2363Z9	T53I1_HUMAN	Increases Expression	[62]
Transcription factor E2F7 (E2F7)	OTWW358N	E2F7_HUMAN	Decreases Expression	[62]
Spindle and kinetochore-associated protein 1 (SKA1)	OTDYJ12A	SKA1_HUMAN	Decreases Expression	[62]
Mdm2-binding protein (MTBP)	OTWLCW9C	MTBP_HUMAN	Decreases Expression	[62]
Sororin (CDCA5)	OTZLCQ5U	CDCA5_HUMAN	Decreases Expression	[62]
Aurora kinase B (AURKB)	OTIY4VHU	AURKB_HUMAN	Decreases Expression	[62]
Serine/threonine-protein kinase greatwall (MASTL)	OTQ7YKK5	GWL_HUMAN	Decreases Expression	[62]
Centromere protein N (CENPN)	OTRO7XPD	CENPN_HUMAN	Decreases Expression	[62]
Proline-rich protein 11 (PRR11)	OT2JJ08Z	PRR11_HUMAN	Decreases Expression	[62]
Lymphokine-activated killer T-cell-originated protein kinase (PBK)	OT5Z27TW	TOPK_HUMAN	Decreases Expression	[62]
Leucine-rich repeat protein 1 (LRR1)	OTSWDXVY	LLR1_HUMAN	Decreases Expression	[62]
Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 (PCMTD1)	OT5TS6P7	PCMD1_HUMAN	Increases Expression	[62]
Discoidin, CUB and LCCL domain-containing protein 2 (DCBLD2)	OTB71I02	DCBD2_HUMAN	Decreases Expression	[62]
Kinesin-like protein KIF20B (KIF20B)	OTS68AHH	KI20B_HUMAN	Decreases Expression	[62]
ATPase family AAA domain-containing protein 5 (ATAD5)	OTI8ABKF	ATAD5_HUMAN	Decreases Expression	[62]
Hemicentin-1 (HMCN1)	OTLZAS0P	HMCN1_HUMAN	Increases Expression	[62]
Hyaluronan and proteoglycan link protein 3 (HAPLN3)	OTB853Z1	HPLN3_HUMAN	Increases Expression	[62]
Proheparin-binding EGF-like growth factor (HBEGF)	OTLU00JS	HBEGF_HUMAN	Decreases Expression	[62]
Cell division cycle-associated protein 3 (CDCA3)	OTUI8QK3	CDCA3_HUMAN	Decreases Expression	[62]
Kinesin-like protein KIF2C (KIF2C)	OTJ8G3NP	KIF2C_HUMAN	Decreases Expression	[62]
Cell division control protein 6 homolog (CDC6)	OTX93FE7	CDC6_HUMAN	Decreases Expression	[62]
Endothelial PAS domain-containing protein 1 (EPAS1)	OTRE3O8U	EPAS1_HUMAN	Increases Expression	[62]
Histone H2B type 1-M (H2BC14)	OTSDZZZY	H2B1M_HUMAN	Decreases Expression	[62]
Condensin complex subunit 3 (NCAPG)	OT1AI9EO	CND3_HUMAN	Decreases Expression	[62]
Mitochondrial genome maintenance exonuclease 1 (MGME1)	OTC5LPXX	MGME1_HUMAN	Decreases Expression	[62]
Synaptotagmin-15 (SYT15)	OT7Q088G	SYT15_HUMAN	Increases Expression	[62]
Hephaestin (HEPH)	OTZ2F15Z	HEPH_HUMAN	Increases Expression	[62]
DNA replication complex GINS protein SLD5 (GINS4)	OTCVOO3S	SLD5_HUMAN	Decreases Expression	[62]
Centromere protein K (CENPK)	OTKPUF8K	CENPK_HUMAN	Decreases Expression	[62]
Protein PIMREG (PIMREG)	OTKC8T3E	PIMRE_HUMAN	Decreases Expression	[62]
Nucleoporin NDC1 (NDC1)	OTF2GQC1	NDC1_HUMAN	Decreases Expression	[62]
Centromere protein O (CENPO)	OTXAH83Y	CENPO_HUMAN	Decreases Expression	[62]
Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1)	OTJGE772	CHAC1_HUMAN	Increases Expression	[62]
TIMELESS-interacting protein (TIPIN)	OT9PZHXV	TIPIN_HUMAN	Decreases Expression	[62]
Kinesin-like protein KIFC1 (KIFC1)	OTNQDS00	KIFC1_HUMAN	Decreases Expression	[62]
Meiotic nuclear division protein 1 homolog (MND1)	OTS87F3H	MND1_HUMAN	Decreases Expression	[62]
Nucleolar and spindle-associated protein 1 (NUSAP1)	OT85HIJ5	NUSAP_HUMAN	Decreases Expression	[62]
Fanconi anemia group D2 protein (FANCD2)	OTVEB5LF	FACD2_HUMAN	Decreases Expression	[62]
Transmembrane 6 superfamily member 1 (TM6SF1)	OTQR4I2N	TM6S1_HUMAN	Increases Expression	[62]
Cysteine-rich secretory protein LCCL domain-containing 2 (CRISPLD2)	OTVSFHTL	CRLD2_HUMAN	Increases Expression	[62]
Rac GTPase-activating protein 1 (RACGAP1)	OTQE8IEH	RGAP1_HUMAN	Decreases Expression	[62]
Centromere protein H (CENPH)	OTPOO9LK	CENPH_HUMAN	Decreases Expression	[62]
Kinetochore-associated protein DSN1 homolog (DSN1)	OTHROI0H	DSN1_HUMAN	Decreases Expression	[62]
Uncharacterized protein C1orf198 (C1ORF198)	OTK3L4G7	CA198_HUMAN	Increases Expression	[62]
Golgi-associated plant pathogenesis-related protein 1 (GLIPR2)	OTFTH6ZY	GAPR1_HUMAN	Increases Expression	[62]
Very long chain fatty acid elongase 6 (ELOVL6)	OTB26UJJ	ELOV6_HUMAN	Decreases Expression	[62]
Anthrax toxin receptor 1 (ANTXR1)	OT5W1GPC	ANTR1_HUMAN	Increases Expression	[62]
Gremlin-2 (GREM2)	OTE91EWT	GREM2_HUMAN	Increases Expression	[62]
Metal transporter CNNM2 (CNNM2)	OTZHO8WU	CNNM2_HUMAN	Increases Expression	[62]
Protein ECT2 (ECT2)	OTQDUCT6	ECT2_HUMAN	Decreases Expression	[62]
Claspin (CLSPN)	OTZZXNDK	CLSPN_HUMAN	Decreases Expression	[62]
Mineralization regulator ANKH (ANKH)	OTCN25R5	ANKH_HUMAN	Increases Expression	[62]
Ribonucleoprotein PTB-binding 2 (RAVER2)	OT0MDL7K	RAVR2_HUMAN	Increases Expression	[62]
Neurexin-3-beta (NRXN3)	OTJ0I7HJ	NRX3B_HUMAN	Increases Expression	[62]
Solute carrier family 40 member 1 (SLC40A1)	OT8RV2VY	S40A1_HUMAN	Increases Expression	[62]
Anillin (ANLN)	OTXJY54C	ANLN_HUMAN	Decreases Expression	[62]
Phospholipid scramblase 4 (PLSCR4)	OT2AMYLY	PLS4_HUMAN	Increases Expression	[62]
Lymphoid-specific helicase (HELLS)	OTVVV668	HELLS_HUMAN	Decreases Expression	[62]
FIGNL1-interacting regulator of recombination and mitosis (FIRRM)	OTALLHT1	FIRRM_HUMAN	Decreases Expression	[62]
Protein diaphanous homolog 3 (DIAPH3)	OTPOT23F	DIAP3_HUMAN	Decreases Expression	[62]
Structural maintenance of chromosomes protein 4 (SMC4)	OTEJE6AG	SMC4_HUMAN	Decreases Expression	[62]
Protein DEPP1 (DEPP1)	OTB36PHJ	DEPP1_HUMAN	Increases Expression	[62]
Tyrosyl-DNA phosphodiesterase 1 (TDP1)	OTYINMBR	TYDP1_HUMAN	Decreases Expression	[62]
Fanconi anemia group I protein (FANCI)	OTW8E3SC	FANCI_HUMAN	Decreases Expression	[62]
Histone chaperone ASF1B (ASF1B)	OTKXX12I	ASF1B_HUMAN	Decreases Expression	[62]
PCNA-interacting partner (PARPBP)	OTPZDGW7	PARI_HUMAN	Decreases Expression	[62]
DNA damage-inducible transcript 4 protein (DDIT4)	OTHY8SY4	DDIT4_HUMAN	Increases Expression	[62]
Dapper homolog 1 (DACT1)	OT19Z704	DACT1_HUMAN	Increases Expression	[62]
Protein Mis18-alpha (MIS18A)	OTD80K5X	MS18A_HUMAN	Decreases Expression	[62]
Denticleless protein homolog (DTL)	OTC29RYE	DTL_HUMAN	Decreases Expression	[62]
Programmed cell death 1 ligand 1 (CD274)	OTJ0VFDL	PD1L1_HUMAN	Decreases Expression	[62]
LIM and cysteine-rich domains protein 1 (LMCD1)	OT3AWE8O	LMCD1_HUMAN	Increases Expression	[62]
Calcium-binding and coiled-coil domain-containing protein 1 (CALCOCO1)	OT1PAIN0	CACO1_HUMAN	Increases Expression	[62]
Homologous-pairing protein 2 homolog (PSMC3IP)	OT9UB5UO	HOP2_HUMAN	Decreases Expression	[62]
Fibulin-5 (FBLN5)	OTLVNZ8U	FBLN5_HUMAN	Increases Expression	[62]
DNA dC->dU-editing enzyme APOBEC-3B (APOBEC3B)	OTHLNI51	ABC3B_HUMAN	Decreases Expression	[62]
STEAP1 protein (STEAP1)	OTJMW5R9	STEA1_HUMAN	Decreases Expression	[62]
Carboxypeptidase A4 (CPA4)	OT66MP0F	CBPA4_HUMAN	Decreases Expression	[62]
DNA helicase MCM8 (MCM8)	OTC93H3S	MCM8_HUMAN	Decreases Expression	[62]
F-box only protein 5 (FBXO5)	OTTR957W	FBX5_HUMAN	Decreases Expression	[62]
Angiopoietin-related protein 2 (ANGPTL2)	OTB6JG41	ANGL2_HUMAN	Increases Expression	[62]
Integrin alpha-11 (ITGA11)	OTBWSRA1	ITA11_HUMAN	Increases Expression	[62]
Protein HEG homolog 1 (HEG1)	OT3CUXA7	HEG1_HUMAN	Increases Expression	[62]
Targeting protein for Xklp2 (TPX2)	OTWLJYH0	TPX2_HUMAN	Decreases Expression	[62]
Synaptopodin-2 (SYNPO2)	OTC3U0YH	SYNP2_HUMAN	Increases Expression	[62]
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS5)	OT953SV2	ATS5_HUMAN	Increases Expression	[62]
Protein timeless homolog (TIMELESS)	OTD8DCBJ	TIM_HUMAN	Decreases Expression	[62]
LIM and calponin homology domains-containing protein 1 (LIMCH1)	OTYPC4XA	LIMC1_HUMAN	Increases Expression	[62]
Exonuclease 1 (EXO1)	OTI87RS5	EXO1_HUMAN	Decreases Expression	[62]
Protein phosphatase 1 regulatory subunit 3C (PPP1R3C)	OTEU05TX	PPR3C_HUMAN	Increases Expression	[62]
Transcription factor 19 (TCF19)	OT7NKLF9	TCF19_HUMAN	Decreases Expression	[62]
DNA replication complex GINS protein PSF2 (GINS2)	OT974IYI	PSF2_HUMAN	Decreases Expression	[62]
Serine/threonine-protein kinase 38-like (STK38L)	OTI00JVW	ST38L_HUMAN	Increases Expression	[62]
Small kinetochore-associated protein (KNSTRN)	OTYA7UXS	SKAP_HUMAN	Decreases Expression	[62]
Origin recognition complex subunit 6 (ORC6)	OTKQN3KP	ORC6_HUMAN	Decreases Expression	[62]
Phosphoserine aminotransferase (PSAT1)	OTVV1YV9	SERC_HUMAN	Increases Expression	[62]
Carboxypeptidase Q (CPQ)	OTTNZNLD	CBPQ_HUMAN	Increases Expression	[62]
Transforming acidic coiled-coil-containing protein 3 (TACC3)	OTRNEZTA	TACC3_HUMAN	Decreases Expression	[62]
Inositol 1,4,5-triphosphate receptor associated 1 (IRAG1)	OTMRW5U5	IRAG1_HUMAN	Increases Expression	[62]
Adenylate kinase isoenzyme 5 (AK5)	OTTGXLOT	KAD5_HUMAN	Decreases Expression	[62]
Bile salt export pump (ABCB11)	OTRU7THO	ABCBB_HUMAN	Decreases Activity	[70]
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS)	OTFBFPV4	ADAS_HUMAN	Increases Expression	[71]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Decreases Expression	[71]
Poly polymerase 1 (PARP1)	OT310QSG	PARP1_HUMAN	Increases Cleavage	[71]
Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1)	OT5BZ1J9	P85A_HUMAN	Decreases Phosphorylation	[71]
RAC-alpha serine/threonine-protein kinase (AKT1)	OT8H2YY7	AKT1_HUMAN	Decreases Phosphorylation	[71]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Decreases Expression	[71]
cAMP-regulated phosphoprotein 19 (ARPP19)	OTZS3IT6	ARP19_HUMAN	Increases Expression	[71]
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3)	OTPGHZB9	IFIT3_HUMAN	Increases Expression	[72]
Apoptosis-inducing factor 1, mitochondrial (AIFM1)	OTKPWB7Q	AIFM1_HUMAN	Affects Localization	[73]
Tyrosine-protein kinase ABL1 (ABL1)	OT09YVXH	ABL1_HUMAN	Decreases Activity	[74]
Myc proto-oncogene protein (MYC)	OTPV5LUK	MYC_HUMAN	Decreases Expression	[72]
Transforming growth factor beta-1 proprotein (TGFB1)	OTV5XHVH	TGFB1_HUMAN	Decreases Activity	[75]
Tumor necrosis factor (TNF)	OT4IE164	TNFA_HUMAN	Decreases Expression	[76]
Interferon gamma (IFNG)	OTXG9JM7	IFNG_HUMAN	Decreases Expression	[76]
C-X-C motif chemokine 10 (CXCL10)	OTTLQ6S0	CXL10_HUMAN	Increases Expression	[72]
Granulocyte-macrophage colony-stimulating factor (CSF2)	OT1M7D28	CSF2_HUMAN	Decreases Expression	[76]
Cytochrome P450 1A1 (CYP1A1)	OTE4EFH8	CP1A1_HUMAN	Decreases Activity	[77]
Interleukin-5 (IL5)	OTAFPSCO	IL5_HUMAN	Decreases Expression	[76]
Cathepsin B (CTSB)	OTP9G5QB	CATB_HUMAN	Decreases Expression	[78]
Tyrosine-protein kinase Lyn (LYN)	OTP686K2	LYN_HUMAN	Decreases Activity	[63]
Hepatocyte growth factor receptor (MET)	OT7K55MU	MET_HUMAN	Decreases Phosphorylation	[79]
Growth-regulated alpha protein (CXCL1)	OT3WCTZV	GROA_HUMAN	Decreases Expression	[76]
High mobility group protein B1 (HMGB1)	OT4B7CPF	HMGB1_HUMAN	Increases Expression	[80]
Interleukin-8 (CXCL8)	OTS7T5VH	IL8_HUMAN	Decreases Activity	[78]
C-C motif chemokine 3 (CCL3)	OTW2H3ND	CCL3_HUMAN	Decreases Expression	[76]
Apoptosis regulator Bcl-2 (BCL2)	OT9DVHC0	BCL2_HUMAN	Decreases Expression	[81]
Mast/stem cell growth factor receptor Kit (KIT)	OTHUY3VZ	KIT_HUMAN	Decreases Phosphorylation	[82]
Integrin alpha-M (ITGAM)	OTAG6HWU	ITAM_HUMAN	Increases Expression	[72]
Breakpoint cluster region protein (BCR)	OTCN76C1	BCR_HUMAN	Decreases Activity	[74]
C-C motif chemokine 4 (CCL4)	OT6B8P25	CCL4_HUMAN	Decreases Expression	[76]
C-C motif chemokine 2 (CCL2)	OTAD2HEL	CCL2_HUMAN	Decreases Activity	[78]
C-C motif chemokine 5 (CCL5)	OTSCA5CK	CCL5_HUMAN	Decreases Expression	[76]
Interleukin-1 receptor type 1 (IL1R1)	OTTU8959	IL1R1_HUMAN	Decreases Expression	[76]
Platelet-derived growth factor receptor alpha (PDGFRA)	OTDJXUCN	PGFRA_HUMAN	Decreases Phosphorylation	[83]
C-C motif chemokine 1 (CCL1)	OT23NON8	CCL1_HUMAN	Decreases Expression	[76]
G1/S-specific cyclin-D1 (CCND1)	OT8HPTKJ	CCND1_HUMAN	Decreases Expression	[84]
Mitogen-activated protein kinase 3 (MAPK3)	OTCYKGKO	MK03_HUMAN	Decreases Phosphorylation	[63]
Mitogen-activated protein kinase 1 (MAPK1)	OTH85PI5	MK01_HUMAN	Decreases Phosphorylation	[63]
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38)	OTG0TTX7	CD38_HUMAN	Decreases Expression	[76]
G1/S-specific cyclin-D3 (CCND3)	OTNKPQ22	CCND3_HUMAN	Decreases Expression	[84]
Receptor-type tyrosine-protein kinase FLT3 (FLT3)	OTMSRYMK	FLT3_HUMAN	Decreases Phosphorylation	[82]
Signal transducer and activator of transcription 3 (STAT3)	OTAAGKYZ	STAT3_HUMAN	Decreases Phosphorylation	[85]
Serine/threonine-protein kinase mTOR (MTOR)	OTHH8KU7	MTOR_HUMAN	Decreases Phosphorylation	[81]
Caspase-3 (CASP3)	OTIJRBE7	CASP3_HUMAN	Increases Activity	[74]
Tyrosine-protein kinase ABL2 (ABL2)	OTS8F4GD	ABL2_HUMAN	Affects Binding	[86]
Crk-like protein (CRKL)	OTOYSD1R	CRKL_HUMAN	Decreases Phosphorylation	[87]
Cyclin-dependent kinase inhibitor 1B (CDKN1B)	OTNY5LLZ	CDN1B_HUMAN	Increases Expression	[84]
Stromal cell-derived factor 1 (CXCL12)	OT2QX5LL	SDF1_HUMAN	Decreases Expression	[76]
Paxillin (PXN)	OTVMMUOF	PAXI_HUMAN	Decreases Phosphorylation	[85]
Caspase-7 (CASP7)	OTAPJ040	CASP7_HUMAN	Increases Cleavage	[63]
Caspase-9 (CASP9)	OTD4RFFG	CASP9_HUMAN	Increases Activity	[88]
Interleukin-2 (IL2)	OTGI4NSA	IL2_HUMAN	Decreases Expression	[76]
Small ribosomal subunit protein eS6 (RPS6)	OTT4D1LN	RS6_HUMAN	Decreases Phosphorylation	[76]
Mothers against decapentaplegic homolog 3 (SMAD3)	OTNA96MR	SMAD3_HUMAN	Decreases Phosphorylation	[75]
Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1)	OT4Y9NQI	MP2K1_HUMAN	Increases Phosphorylation	[72]
Focal adhesion kinase 1 (PTK2)	OT3Q1JDY	FAK1_HUMAN	Decreases Phosphorylation	[84]
Early activation antigen CD69 (CD69)	OTGJHSVP	CD69_HUMAN	Decreases Expression	[76]
Bcl-2-like protein 1 (BCL2L1)	OTRC5K9O	B2CL1_HUMAN	Decreases Expression	[63]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)	OT2YYI1A	MCL1_HUMAN	Decreases Expression	[63]
Caspase-8 (CASP8)	OTA8TVI8	CASP8_HUMAN	Increases Activity	[88]
Pre-mRNA 3'-end-processing factor FIP1 (FIP1L1)	OTF91GTL	FIP1_HUMAN	Decreases Phosphorylation	[83]
Bile acid receptor (NR1H4)	OTWZLPTB	NR1H4_HUMAN	Decreases Phosphorylation	[89]
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1)	OTYRXD2T	PMYT1_HUMAN	Decreases Activity	[90]
Transcription factor SOX-17 (SOX17)	OT9H4WWE	SOX17_HUMAN	Decreases Localization	[91]
Diablo IAP-binding mitochondrial protein (DIABLO)	OTHJ9MCZ	DBLOH_HUMAN	Affects Localization	[73]
Epidermal growth factor receptor (EGFR)	OTAPLO1S	EGFR_HUMAN	Increases Response To Substance	[84]
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL)	OTK3EJFD	NSDHL_HUMAN	Decreases Response To Substance	[92]
Methylsterol monooxygenase 1 (MSMO1)	OTKV62RZ	MSMO1_HUMAN	Decreases Response To Substance	[92]

Test Results of This Drug Combination in Other Disease Systems

Indication	DrugCom ID	Cell Line	Status	REF
Anaplastic large cell lymphoma	DC5WFJK	SR	Investigative	[93]

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