Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM7DNOG)

Drug Name
SK-7041 Drug Info
Synonyms IN-2001; 4-(dimethylamino)-N-[[4-[(E)-3-(hydroxyamino)-3-oxoprop-1-enyl]phenyl]methyl]benzamide
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Preclinical [1]
Cross-matching ID
PubChem CID
6918714
TTD Drug ID
DM7DNOG

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Histone deacetylase 1 (HDAC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [4]
Romidepsin DMT5GNL Cutaneous T-cell lymphoma 2B01 Approved [5]
Panobinostat DM58WKG Chronic graft versus host disease Approved [4]
HBI-8000 DMDWYUN Non-small-cell lung cancer 2C25.Y Registered [6]
ITF2357 DMFZBNE Duchenne dystrophy 8C70 Phase 3 [7]
NVP-LAQ824 DM8JWNA Mood disorder 6A60-6E23 Phase 3 [8]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [9]
Phenylbutyrate DMBHPDW Urea cycle disorder 5C50.A Phase 2 [10]
MGCD-0103 DM726HX Non-small-cell lung cancer 2C25.Y Phase 2 [4]
Resminostat DMNE1FR Hepatocellular carcinoma 2C12.02 Phase 2 [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G2/mitotic-specific cyclin-B1 (CCNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [12]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [13]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [14]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [15]
Selenium DM25CGV N. A. N. A. Approved [16]
Etretinate DM2CZFA Keratosis ED56 Approved [17]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [18]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [19]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [20]
Methotrexate DM2TEOL Anterior urethra cancer Approved [21]
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Drug(s) Affected By G1/S-specific cyclin-D2 (CCND2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [22]
Selenium DM25CGV N. A. N. A. Approved [16]
Methotrexate DM2TEOL Anterior urethra cancer Approved [23]
Quercetin DM3NC4M Obesity 5B81 Approved [24]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [25]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [26]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [27]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [29]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [30]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [27]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [31]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [14]
Gefitinib DM15F0X Colon adenocarcinoma Approved [32]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [33]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [34]
Etretinate DM2CZFA Keratosis ED56 Approved [17]
Prednisone DM2HG4X Acute asthma CA23 Approved [35]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [18]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [36]
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Drug(s) Affected By Histone H4 (H4C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [37]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [34]
Selenium DM25CGV N. A. N. A. Approved [38]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [20]
Methotrexate DM2TEOL Anterior urethra cancer Approved [39]
Quercetin DM3NC4M Obesity 5B81 Approved [40]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [42]
Panobinostat DM58WKG Chronic graft versus host disease Approved [43]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [44]
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Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [45]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [47]
Selenium DM25CGV N. A. N. A. Approved [38]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [48]
Methotrexate DM2TEOL Anterior urethra cancer Approved [23]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [49]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [50]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [52]
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Drug(s) Affected By Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [53]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [54]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [55]
Methotrexate DM2TEOL Anterior urethra cancer Approved [56]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [57]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [59]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [54]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [60]
Ethacrynic acid DM60QMR Edema MG29 Approved [61]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone deacetylase 1 (HDAC1) TT6R7JZ HDAC1_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [3]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [3]
G1/S-specific cyclin-D2 (CCND2) OTDULQF9 CCND2_HUMAN Gene/Protein Processing [3]
G2/mitotic-specific cyclin-B1 (CCNB1) OT19S7E5 CCNB1_HUMAN Gene/Protein Processing [3]
Histone H4 (H4C1) OTB71W46 H4_HUMAN Post-Translational Modifications [3]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) OT2YYI1A MCL1_HUMAN Gene/Protein Processing [3]

References

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