General Information of Drug (ID: DMBDPY0)

Drug Name
Domperidone Drug Info
Synonyms
Domperidon; Domperidona; Domperidonum; Motilium; Nauzelin; KW 5338; NCI299589; Costi (TN); D-122; Domperidona [INN-Spanish]; Domperidonum [INN-Latin]; HS-0067; KW-5338; Motilium (TN); Motillium (TN); Motinorm (TN); R 33,812; R-33812; R-33,812; Domperidone (JAN/USAN/INN); Domperidone [USAN:BAN:INN:JAN]; 4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine; 5-Chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone; 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one; 5-Chloro-1-[1-[3-(2-oxo-1-benzimidazolinyl)propyl]-4-piperidyl]-2-benzimidazolinone; 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one; 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one; 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
Indication
Disease Entry ICD 11 Status REF
Gastrointestinal disease DE2Z Approved [1]
Gastroparesis DA41.00 Approved [2]
Therapeutic Class
Antiemetics
Cross-matching ID
PubChem CID
3151
ChEBI ID
CHEBI:31515
CAS Number
CAS 57808-66-9
TTD Drug ID
DMBDPY0
VARIDT Drug ID
DR00963
INTEDE Drug ID
DR0527

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Drug(s) Targeting Dopamine D2 receptor (D2R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [13]
Haloperidol DM96SE0 Delirium Approved [14]
Perphenazine DMA4MRX Schizophrenia 6A20 Approved [15]
Perazine DM2AOTZ Psychotic disorder 6A20-6A25 Approved [16]
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [17]
Quetiapine DM1N62C Anorexia nervosa cachexia 6B80 Approved [18]
Pimozide DMW83TP Schizophrenia 6A20 Approved [19]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [20]
Iloperidone DM6AUFY Schizophrenia 6A20 Approved [21]
Risperidone DMN6DXL Bipolar I disorder Approved [22]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [23]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [24]
Methotrexate DM2TEOL Anterior urethra cancer Approved [25]
Folic Acid DMEMBJC Colorectal carcinoma Approved [26]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [25]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [25]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [27]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [25]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [28]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [29]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [30]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [31]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [32]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [33]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [34]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [35]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [36]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [37]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [31]
Verapamil DMA7PEW Angina pectoris BA40 Approved [38]
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Drug(s) Metabolized By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [39]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [40]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [41]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [42]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [43]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [44]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [36]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [45]
Verapamil DMA7PEW Angina pectoris BA40 Approved [46]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [47]
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [93]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [93]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [93]
Capsaicin DMGMF6V Back pain ME84.Z Approved [89]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [94]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [95]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [96]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [97]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [98]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [99]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [48]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [49]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [50]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [34]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [38]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [51]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [52]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [53]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [54]
Propranolol DM79NTF Angina pectoris BA40 Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [83]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [84]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [85]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Oxatomide DM1F42Z Hay fever CA08.00 Approved [87]
Cinacalcet DMCX0K3 Hyperparathyroidism 5A51 Approved [88]
Capsaicin DMGMF6V Back pain ME84.Z Approved [89]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [90]
Quinidine DMLPICK N. A. N. A. Approved [91]
Buprenorphine DMPRI8G Opioid dependence 6C43.2Z Approved [92]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Metabolized By Cytochrome P450 3A5 (CYP3A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [56]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [57]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [58]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [7]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [59]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [60]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [61]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [62]
Verapamil DMA7PEW Angina pectoris BA40 Approved [63]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [7]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 3A7 (CYP3A7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [64]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [7]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [7]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [7]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [65]
Verapamil DMA7PEW Angina pectoris BA40 Approved [66]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [7]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [7]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [7]
Metronidazole DMTIVEN Abscess Approved [67]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [68]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [68]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [65]
Verapamil DMA7PEW Angina pectoris BA40 Approved [69]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [70]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [71]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [68]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [72]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [73]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [110]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [111]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [110]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [111]
Sulfinpyrazone DMEV954 Gout FA25 Approved [112]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [110]
Zafirlukast DMHNQOG Asthma CA23 Approved [110]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [110]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [113]
Dabrafenib DMX6OE3 Melanoma 2C30 Approved [114]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [74]
Verapamil DMA7PEW Angina pectoris BA40 Approved [65]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [75]
Estrone DM5T6US Acne vulgaris ED80 Approved [76]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [77]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [78]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [79]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [80]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [81]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [82]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [100]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [101]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [102]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [103]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [104]
Clopidogrel DMOL54H Acute coronary syndrome BA41 Approved [105]
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [106]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [107]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [108]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [109]
⏷ Show the Full List of 20 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [115]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [116]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [117]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [118]
Cepharanthine DM9Y5JB N. A. N. A. Approved [119]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [120]
Clozapine DMFC71L Schizophrenia 6A20 Approved [121]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [122]
Trifluoperazine DMKBYWI Anxiety Approved [123]
Olanzapine DMPFN6Y Bipolar depression Approved [121]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [124]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [125]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [126]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [127]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [128]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [129]
Ethacrynic acid DM60QMR Edema MG29 Approved [130]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [131]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [132]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [133]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [99]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [135]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [136]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [138]
Prednisone DM2HG4X Acute asthma CA23 Approved [139]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [140]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [141]
Methotrexate DM2TEOL Anterior urethra cancer Approved [142]
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Drug(s) Affected By Prolactin (PRL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [143]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [144]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [145]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [146]
Methotrexate DM2TEOL Anterior urethra cancer Approved [142]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [147]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [148]
Aripiprazole DM3NUMH Bipolar I disorder Approved [149]
Fluoxetine DM3PD2C Bipolar depression Approved [150]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [151]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [152]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [153]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [154]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [155]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [156]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [157]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [158]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [159]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [160]
Methotrexate DM2TEOL Anterior urethra cancer Approved [152]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metoclopramide DMFA5MY Nausea MD90 Approved [11]
Quinidine DMLPICK N. A. N. A. Approved [161]
Verapamil DMA7PEW Angina pectoris BA40 Approved [162]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [163]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [163]
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [164]
Propranolol DM79NTF Angina pectoris BA40 Approved [165]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [166]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [167]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [163]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Alfuzosin DMZVMKF Benign prostatic hyperplasia GA90 Approved [168]
Verapamil DMA7PEW Angina pectoris BA40 Approved [169]
Epinephrine DM3KJBC Acute asthma CA23 Approved [170]
Oxymetazoline DM8ZXT6 Arrhythmia BC9Z Approved [171]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [172]
Terbutaline DMD4381 Asthma CA23 Approved [173]
Methoxamine DMF5XQH Hypertension BA00-BA04 Approved [171]
Quinidine DMLPICK N. A. N. A. Approved [169]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [173]
Norepinephrine DMOUC09 Alopecia ED70 Approved [171]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dopamine D2 receptor (D2R) TTEX248 DRD2_HUMAN Antagonist [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [4]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [5]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Substrate [6]
Cytochrome P450 1A2 (CYP1A2) DEJGDUW CP1A2_HUMAN Substrate [6]
Cytochrome P450 3A5 (CYP3A5) DEIBDNY CP3A5_HUMAN Substrate [7]
Cytochrome P450 2B6 (CYP2B6) DEPKLMQ CP2B6_HUMAN Substrate [6]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [6]
Cytochrome P450 3A7 (CYP3A7) DERD86B CP3A7_HUMAN Substrate [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alpha-1D adrenergic receptor (ADRA1D) OTW2CD1O ADA1D_HUMAN Drug Response [8]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Drug Response [8]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Gene/Protein Processing [9]
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Biotransformations [6]
Cytochrome P450 2B6 (CYP2B6) OTOYO4S7 CP2B6_HUMAN Biotransformations [6]
Cytochrome P450 2C8 (CYP2C8) OTHCWT42 CP2C8_HUMAN Biotransformations [6]
Cytochrome P450 2D6 (CYP2D6) OTZJC802 CP2D6_HUMAN Biotransformations [6]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Gene/Protein Processing [10]
Potassium voltage-gated channel subfamily H member 2 (KCNH2) OTZX881H KCNH2_HUMAN Gene/Protein Processing [11]
Prolactin (PRL) OTWFQGX7 PRL_HUMAN Gene/Protein Processing [12]

References

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2 Clinical guideline: management of gastroparesis. Am J Gastroenterol. 2013 Jan;108(1):18-37; quiz 38.
3 Screening of domperidone in wastewater by high performance liquid chromatography and solid phase extraction methods. Talanta. 2006 Jan 15;68(3):928-31.
4 Identification of P-glycoprotein substrates and inhibitors among psychoactive compounds--implications for pharmacokinetics of selected substrates. J Pharm Pharmacol. 2004 Aug;56(8):967-75.
5 Characterization of CYP3A isozymes involved in the metabolism of domperidone: role of cytochrome b5 and inhibition by ketoconazole. Drug Metab Lett. 2010 Apr;4(2):95-103.
6 Characterization of human cytochrome P450 enzymes catalyzing domperidone N-dealkylation and hydroxylation in vitro. Br J Clin Pharmacol. 2004 Sep;58(3):277-87.
7 Drug Interactions Flockhart Table
8 Domperidone treatment for gastroparesis: demographic and pharmacogenetic characterization of clinical efficacy and side-effects. Dig Dis Sci. 2011 Jan;56(1):115-24. doi: 10.1007/s10620-010-1472-2. Epub 2010 Nov 10.
9 Prediction of aryl hydrocarbon receptor-mediated enzyme induction of drugs and chemicals by mRNA quantification. Chem Res Toxicol. 1998 Dec;11(12):1447-52.
10 Plasma cytokine concentration and the cytokine producing ability of whole blood cell cultures from healthy females with pharmacologically induced hyperprolactinemia. Int J Tissue React. 1999;21(2):43-9.
11 Comparison of the effects of metoclopramide and domperidone on HERG channels. Pharmacology. 2005 Apr;74(1):31-6. doi: 10.1159/000083234. Epub 2005 Jan 7.
12 [Importance of prolactin level indication in detection of Sheehan syndrome]. Ginekol Pol. 1992 May;63(5):232-5.
13 The Detection of Dopamine Gene Receptors (DRD1-DRD5) Expression on Human Peripheral Blood Lymphocytes by Real Time PCR. Iran J Allergy Asthma Immunol. 2004 Dec;3(4):169-74.
14 Dopaminergic synapses in the matrix of the ventrolateral striatum after chronic haloperidol treatment. Synapse. 2002 Aug;45(2):78-85.
15 CYP2D6 and DRD2 genes differentially impact pharmacodynamic sensitivity and time course of prolactin response to perphenazine. Pharmacogenet Genomics. 2007 Nov;17(11):989-93.
16 Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands. Bioorg Med Chem. 2005 Jan 3;13(1):77-87.
17 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3639).
18 Receptor reserve-dependent properties of antipsychotics at human dopamine D2 receptors. Eur J Pharmacol. 2009 Apr 1;607(1-3):35-40.
19 [The benzamides tiapride, sulpiride, and amisulpride in treatment for Tourette's syndrome]. Nervenarzt. 2007 Mar;78(3):264, 266-8, 270-1.
20 Modulatory role of dopamine D2 receptors and fundamental role of L-type Ca2+ channels in the induction of long-term potentiation in the basolateral... Eur J Pharmacol. 2009 Mar 15;606(1-3):90-3.
21 Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
22 Randomized clinical comparison of perospirone and risperidone in patients with schizophrenia: Kansai Psychiatric Multicenter Study. Psychiatry Clin Neurosci. 2009 Jun;63(3):322-8.
23 Human intestinal transporter database: QSAR modeling and virtual profiling of drug uptake, efflux and interactions. Pharm Res. 2013 Apr;30(4):996-1007.
24 MDR1 (ABCB1) G1199A (Ser400Asn) polymorphism alters transepithelial permeability and sensitivity to anticancer agents. Cancer Chemother Pharmacol. 2009 Jun;64(1):183-8.
25 Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade. Cancer Lett. 2016 Jan 1;370(1):153-64.
26 Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia. Pregnancy Hypertens. 2012 Apr;2(2):123-31.
27 Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein. Pharm Res. 2001 Dec;18(12):1660-8.
28 Antiestrogens and steroid hormones: substrates of the human P-glycoprotein. Biochem Pharmacol. 1994 Jul 19;48(2):287-92.
29 Association of genetic polymorphisms in the influx transporter SLCO1B3 and the efflux transporter ABCB1 with imatinib pharmacokinetics in patients with chronic myeloid leukemia. Ther Drug Monit. 2011 Apr;33(2):244-50.
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