Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMNGY0E)

• Drug Name: 1-anilinonaphthalene-8-sulfonic acid Drug Info
• Synonyms: CHEMBL471741; SCHEMBL3327539; BDBM50243721; 8-(Phenylamino)naphthalene-1-ol sulfate
• Cross-matching ID:
  PubChem CID: 1369
  ChEBI ID: CHEMBL285527
  CAS Number: CAS 82-76-8
  TTD Drug ID: DMNGY0E

Molecule-Related Drug Atlas

Drug(s) Targeting Fatty acid-binding protein 1 (FABP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
FENOFIBRIC ACID	DMGO2MC	Cardiovascular disease	BA00-BE2Z	Approved	[1]
INDOPROFEN	DM5QSKN	Gout	FA25	Withdrawn from market	[1]
OLEIC ACID	DM54O1Z	Discovery agent	N.A.	Investigative	[1]

Drug(s) Affected By Protein AMBP (AMBP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[2]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[4]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[5]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[6]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[7]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[8]
Benazepril	DMH1M9B	Hypertension	BA00-BA04	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[10]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[11]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[12]

Drug(s) Affected By Alpha-1-acid glycoprotein 1 (ORM1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Lidocaine	DML4ZOT	Anaesthesia	9A78.6	Approved	[13]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[14]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[15]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[16]
Chlorpromazine	DMBGZI3	Acute intermittent hepatic porphyria	5C58.11	Approved	[13]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[17]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[17]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[18]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[14]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[8]

Drug(s) Affected By Apolipoprotein D (APOD)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[19]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[20]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[8]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[21]
Vitamin A	DMJ2AH4	Night blindness	9D45	Approved	[2]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[22]
Chloroquine	DMSI5CB	Malaria	1F40-1F45	Approved	[23]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[11]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[19]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[24]

Drug(s) Affected By Complement component C8 gamma chain (C8G)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[14]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[25]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[7]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[8]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[25]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[10]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[12]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[7]
Urethane	DM7NSI0	N. A.	N. A.	Phase 4	[26]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[7]

Drug(s) Affected By Glycodelin (PAEP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[14]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[17]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[17]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[14]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[27]
Azathioprine	DMMZSXQ	Lupus nephritis	4A40.0Y	Approved	[28]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[10]
Azacitidine	DMTA5OE	Acute myelogenous leukaemia	2A41	Approved	[29]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[30]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[31]

Drug(s) Affected By Lipocalin-1 (LCN1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[2]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[32]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[8]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[33]
Triclosan	DMZUR4N	Malaria	1F40-1F45	Approved	[34]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[35]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[36]

Drug(s) Affected By Prostaglandin-H2 D-isomerase (PTGDS)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[37]
Selenium	DM25CGV	N. A.	N. A.	Approved	[38]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[39]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[40]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[41]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[8]
Mifepristone	DMGZQEF	Cushing disease	5A70	Approved	[42]
Vitamin A	DMJ2AH4	Night blindness	9D45	Approved	[2]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[31]
Triclosan	DMZUR4N	Malaria	1F40-1F45	Approved	[34]

Drug(s) Affected By Odorant-binding protein 2a (OBP2A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[36]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[2]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[8]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[43]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fatty acid-binding protein 1 (FABP1)	TTIV96N	FABPL_HUMAN	Inhibitor	[1]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Alpha-1-acid glycoprotein 1 (ORM1)	OTZKSBRE	A1AG1_HUMAN	Protein Interaction/Cellular Processes	[2]
Apolipoprotein D (APOD)	OTT77XW8	APOD_HUMAN	Protein Interaction/Cellular Processes	[2]
Complement component C8 gamma chain (C8G)	OTZM027I	CO8G_HUMAN	Protein Interaction/Cellular Processes	[2]
Glycodelin (PAEP)	OTQA0NV4	PAEP_HUMAN	Protein Interaction/Cellular Processes	[2]
Lipocalin-1 (LCN1)	OT8BWXTV	LCN1_HUMAN	Protein Interaction/Cellular Processes	[2]
Odorant-binding protein 2a (OBP2A)	OTBIJ5TI	OBP2A_HUMAN	Protein Interaction/Cellular Processes	[2]
Prostaglandin-H2 D-isomerase (PTGDS)	OT71NN7C	PTGDS_HUMAN	Protein Interaction/Cellular Processes	[2]
Protein AMBP (AMBP)	OTLU8GU8	AMBP_HUMAN	Protein Interaction/Cellular Processes	[2]
Transthyretin	OTAFXQRA	TTHY_HUMAN	Protein Interaction/Cellular Processes	[3]

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