General Information of Drug (ID: DMOVJP3)

Drug Name
xamoterol Drug Info
Synonyms ICI-118587
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
155774
ChEBI ID
CHEBI:10055
CAS Number
CAS 81801-12-9
TTD Drug ID
DMOVJP3

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mirabegron DMS1GYT Overactive bladder GC50.0 Approved [5]
Trihexyphenidyl DMB19L8 Dystonia 8A02 Approved [6]
Amosulalol DML8QSZ Hypertension BA00-BA04 Approved [7]
Bopindolol DMIFYLX Hypertension BA00-BA04 Approved [8]
Mepindolol DMUDWP9 Angina pectoris BA40 Approved [9]
Rimiterol DMA47C6 Asthma CA23 Approved [10]
Bitolterol DMK6XAV Chronic obstructive pulmonary disease CA22 Approved [11]
Nipradilol DMA65ER Angina pectoris BA40 Approved [12]
Vibegron DMFR201 Overactive bladder GC50.0 Approved [13]
ONO-2506 DMCA2PJ Stroke 8B20 Phase 2/3 [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [15]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [16]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [17]
Selenium DM25CGV N. A. N. A. Approved [18]
Methotrexate DM2TEOL Anterior urethra cancer Approved [19]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [21]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [21]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [22]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [23]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [17]
Quercetin DM3NC4M Obesity 5B81 Approved [24]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [25]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [26]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [27]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [28]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [29]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [30]
Pelitinib DMIW453 Lymphoma 2A80-2A86 Phase 2 [31]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [32]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [33]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [16]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [34]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [35]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [36]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [37]
Gefitinib DM15F0X Colon adenocarcinoma Approved [38]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [39]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [40]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [41]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [33]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [42]
Paclitaxel DMLB81S Breast carcinoma Approved [43]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [44]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [32]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [4]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [45]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [34]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [35]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [47]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [48]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [49]
Oxatomide DM1F42Z Hay fever CA08.00 Approved [50]
Cinacalcet DMCX0K3 Hyperparathyroidism 5A51 Approved [51]
Capsaicin DMGMF6V Back pain ME84.Z Approved [52]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [53]
Quinidine DMLPICK N. A. N. A. Approved [54]
Buprenorphine DMPRI8G Opioid dependence 6C43.2Z Approved [55]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adrenergic receptor beta-3 (ADRB3) TTMXGCW ADRB3_HUMAN Agonist [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Cyclic AMP-dependent transcription factor ATF-1 (ATF1) OT251CI0 ATF1_HUMAN Post-Translational Modifications [3]
Cyclic AMP-responsive element-binding protein 1 (CREB1) OT1MDLA1 CREB1_HUMAN Post-Translational Modifications [3]
Cytochrome P450 2D6 (CYP2D6) OTZJC802 CP2D6_HUMAN Drug Response [4]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Post-Translational Modifications [3]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Post-Translational Modifications [3]

References

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28 Ketoconazole suppresses prostaglandin E(2)-induced cyclooxygenase-2 expression in human epidermoid carcinoma A-431 cells. J Invest Dermatol. 2002 Jul;119(1):174-81.
29 Gene expression analysis of precision-cut human liver slices indicates stable expression of ADME-Tox related genes. Toxicol Appl Pharmacol. 2011 May 15;253(1):57-69.
30 AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism. J Biol Chem. 2010 Mar 19;285(12):9100-13. doi: 10.1074/jbc.M109.060061. Epub 2010 Jan 14.
31 Irreversible EGFR inhibitor EKB-569 targets low-LET -radiation-triggered rel orchestration and potentiates cell death in squamous cell carcinoma. PLoS One. 2011;6(12):e29705. doi: 10.1371/journal.pone.0029705. Epub 2011 Dec 29.
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41 Downregulation of mitogen-activated protein kinases (MAPKs) in chronic ethanol-induced fatty liver. Toxicol Mech Methods. 2020 Jul;30(6):407-416. doi: 10.1080/15376516.2020.1747126. Epub 2020 Apr 1.
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