Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMSF5DW)

Drug Name

Sanggenon C Drug Info

Synonyms

Sanggenon C; 80651-76-9; 2-[(1S,5S,6R)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-1,3,8,10a-tetrahydroxy-5a-(3-methylbut-2-enyl)-[1]benzofuro[3,2-b]chromen-11-one; AC1L9CVB; Sanggenone-C; C09834; CHEBI:9020; DTXSID20230468

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 442458
ChEBI ID: CHEMBL9020
CAS Number: CAS 80651-76-9
TTD Drug ID: DMSF5DW

Molecule-Related Drug Atlas

Molecule Type:

DTT

DOT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Targeting PTPN1 messenger RNA (PTPN1 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[5]
TRYPAN BLUE	DM4NTMO	Ophthalmic surgery injury	PK97	Approved	[6]
URSOLIC ACID	DM4SOAW	Metabolic syndrome x	5C50-5D2Z	Phase 2	[7]
ISIS 113715	DMUPD4G	Type-2 diabetes	5A11	Phase 2	[8]
ISIS-PTP1Brx	DMJGVXT	Type-2 diabetes	5A11	Phase 2	[9]
ERTIPROTAFIB	DMJXEV7	Type-2 diabetes	5A11	Terminated	[10]
Acetate Ion	DMD08RH	Discovery agent	N.A.	Investigative	[11]
B-Octylglucoside	DMMO75G	Discovery agent	N.A.	Investigative	[11]
2-Methyl-2,4-Pentanediol	DMD45CU	Discovery agent	N.A.	Investigative	[11]
Double Oxidized Cysteine	DM6TU84	Discovery agent	N.A.	Investigative	[11]
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Drug(s) Affected By Dynamin-1-like protein (DNM1L)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[12]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[13]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[14]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[15]
Efavirenz	DMC0GSJ	Human immunodeficiency virus infection	1C62	Approved	[16]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[17]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[18]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[19]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[12]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[20]
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Drug(s) Affected By Cocaine esterase (CES2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[21]
Irinotecan	DMP6SC2	Adenocarcinoma	2D40	Approved	[22]
Dextropropoxyphene	DM23HCX	Pain	MG30-MG3Z	Approved	[23]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[24]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[25]
Tacrine	DM51FY6	Alzheimer disease	8A20	Approved	[26]
Rifampicin	DM5DSFZ	Non-insulin dependent diabetes	5A11	Approved	[27]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[28]
Testosterone enanthate	DMB6871	N. A.	N. A.	Approved	[29]
Cantharidin	DMBP5N3	Molluscum contagiosum infection	1E76	Approved	[30]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[31]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[32]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[33]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[34]
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[35]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[36]
Secobarbital	DM14RF5	Epilepsy	8A60-8A68	Approved	[37]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[38]
Fexofenadine	DM17ONX	Allergic rhinitis	CA08.0	Approved	[39]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[40]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[41]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[32]
Carvedilol	DMHTEAO	Chronic heart failure	BD1Z	Approved	[42]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[43]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[44]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[31]
Urokinase	DM0GOUD	Myocardial infarction	BA41-BA43	Approved	[45]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[46]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[34]
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[35]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[47]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[48]
Prednisone	DM2HG4X	Acute asthma	CA23	Approved	[49]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[50]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[51]
Lapatinib	DM3BH1Y	Breast cancer	2C60-2C65	Approved	[52]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[53]
Fluoxetine	DM3PD2C	Bipolar depression		Approved	[54]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[55]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[56]
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Drug(s) Affected By E3 ubiquitin-protein ligase MIB1 (MIB1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[57]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[58]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[59]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[60]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[61]
Enzalutamide	DMGL19D	Prostate cancer	2C82.0	Approved	[62]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[63]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[64]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[65]
(+)-JQ1	DM1CZSJ	Testicular cancer	2C80	Phase 1	[66]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
PTPN1 messenger RNA (PTPN1 mRNA)	TTELIN2	PTN1_HUMAN	Inhibitor	[1]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Cocaine esterase (CES2)	OTC647SQ	EST2_HUMAN	Gene/Protein Processing	[2]
Cyclin-dependent kinase inhibitor 1B (CDKN1B)	OTNY5LLZ	CDN1B_HUMAN	Gene/Protein Processing	[3]
Dynamin-1-like protein (DNM1L)	OTXK1Q1G	DNM1L_HUMAN	Gene/Protein Processing	[4]
E3 ubiquitin-protein ligase MIB1 (MIB1)	OT5C404P	MIB1_HUMAN	Gene/Protein Processing	[3]
Mitogen-activated protein kinase 1 (MAPK1)	OTH85PI5	MK01_HUMAN	Post-Translational Modifications	[4]
Mitogen-activated protein kinase 3 (MAPK3)	OTCYKGKO	MK03_HUMAN	Post-Translational Modifications	[4]

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