Details of the Drug

General Information of Drug (ID: DM7Q98D)

• Drug Name: Ruxolitinib
• Synonyms: Ruxolitinib (JAK inhibitor)

Indication

Disease Entry	ICD 11	Status	REF
Essential thrombocythemia	3B63.1Z	Approved	[1]
High-risk myelofibrosis	2A20.2	Approved	[2]
Myelofibrosis	2A22	Approved	[3]
Myeloproliferative neoplasm	2A20	Approved	[4]
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 3	[5]
Pancreatic cancer	2C10	Phase 3	[2]
Atopic dermatitis	EA80	Phase 1/2	[6]
Vitiligo	ED63.0	Phase 1/2	[6]

• Affected Organisms: Humans and other mammals
• ATC Code:
  D11AH09: Ruxolitinib
  D11AH: Agents for dermatitis, excluding corticosteroids
  D11A: OTHER DERMATOLOGICAL PREPARATIONS
  D11: OTHER DERMATOLOGICAL PREPARATIONS
  D: DERMATOLOGICALS
  L01EJ01: Ruxolitinib
  L01EJ: Janus-associated kinase (JAK) inhibitors
  L01E: PROTEIN KINASE INHIBITORS
  L01: ANTINEOPLASTIC AGENTS
  L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 306.4
  Logarithm of the Partition Coefficient (xlogp); 2.1
  Rotatable Bond Count (rotbonds); 4
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 4

Adverse Drug Reaction (ADR)

ADR Term	Variation	Related DOT	DOT ID	REF
Anaemia	Not Available	MAPK14	OT5TCO3O	[7]

• Chemical Identifiers:
  Formula: C17H18N6
  IUPAC Name: (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile
  Canonical SMILES: C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
  InChI: InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1
  InChIKey: HFNKQEVNSGCOJV-OAHLLOKOSA-N
• Cross-matching ID:
  PubChem CID: 25126798
  ChEBI ID: CHEBI:66919
  CAS Number: 941678-49-5
  UNII: 82S8X8XX8H
  DrugBank ID: DB08877
  TTD ID: D04LKS
  ACDINA ID: D00611
• Repurposed Drugs (RPD): Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Janus kinase 1 (JAK-1)	TT6DM01	JAK1_HUMAN	Modulator	[8]
Janus kinase 2 (JAK-2)	TTRMX3V	JAK2_HUMAN	Modulator	[8]
Urokinase plasminogen activator surface receptor (PLAUR)	TTPRL03	UPAR_HUMAN	Inhibitor	[9]
HUMAN janus kinase 1 (JAK-1)	TTWKB01	JAK1_HUMAN	Inhibitor	[10]
HUMAN janus kinase 2 (JAK-2)	TT0F5HE	JAK2_HUMAN	Inhibitor	[10]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Mitogen-activated protein kinase 14 (MAPK14)	OT5TCO3O	MK14_HUMAN	Drug Response	[7]

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
RPMI-3460/CS1	GDSC1	4.6264	6.4164	1.7991	0.6336
CHSA0011	GDSC1; GDSC2	3.6317	6.0906	2.1865	6.3358
EW-18	GDSC1; GDSC2	3.8742	6.2141	2.3063	4.9913
CAL-72	GDSC1; GDSC2	3.8915	5.9574	2.4434	4.1084
CADO-ES1	GDSC1; GDSC2	3.9011	6.2792	2.2938	5.0059
NY	GDSC1; GDSC2	4.0207	6.1346	2.4467	3.3623
SK-PN-DW	GDSC1; GDSC2	4.0441	6.8205	2.1318	5.674
EW-13	GDSC1; GDSC2	4.1417	7.5953	1.8239	7.3342
U2OS	GDSC1; GDSC2; CTRP2	4.3687	6.4836	4.0794	12.1996
EW-12	GDSC2	4.4362	7.2282	2.201	4.4343
ES1	GDSC1	4.4614	6.3349	1.7618	0.8993
TC-71	GDSC1; GDSC2	4.5782	7.0451	2.3739	3.1837
ES8	GDSC1; GDSC2	4.5882	8.2945	1.7953	6.5232
EW-24	GDSC1; GDSC2	4.8034	6.0509	2.9079	0.4045
CHSA0108	GDSC1; GDSC2	4.8347	10.404	0.9487	10.8832
MHH-ES-1	GDSC1; GDSC2; CTRP2	4.9486	6.7634	4.597	8.5954
CHSA8926	GDSC1; GDSC2	5.0193	8.6483	1.9052	5.0559
Hs 888.T	CTRP2	5.1294	7.9203	4.2661	9.4507
A-673	GDSC1; GDSC2; CTRP2	5.1794	6.1813	5.0597	6.1875
U-CH2	GDSC2	5.2986	7.4207	2.592	1.1773
SJSA-1	GDSC1; CTRP2	5.352	7.8456	4.5172	7.8936
EW-16	GDSC1; GDSC2	5.4476	7.9773	2.4365	1.6927
HOS	GDSC1; GDSC2; CTRP2	5.4601	9.2005	3.9564	9.9711
TC71	CTRP2	5.4668	6.4687	5.263	4.6018
SW1353	CTRP2	5.4714	7.709	4.6969	6.8763
ES5	GDSC1; GDSC2	5.4934	10.2564	1.4539	6.7242
ES6	GDSC1; GDSC2	5.5556	7.9899	2.4826	1.3898
SK-ES-1	GDSC1; GDSC2; CTRP2	5.558	6.7599	5.2299	4.495
SK-N-MC	CTRP2	5.6186	6.2836	5.498	3.2783
HuO9	GDSC1; GDSC2	5.6576	9.0037	2.1104	2.9805
CAL-78	GDSC1; GDSC2; CTRP2	5.6713	7.0943	5.1834	4.4099
G-292 clone A141B1	GDSC1; GDSC2; CTRP2	5.6978	8.6835	4.4259	7.5029
H-EMC-SS	GDSC1; GDSC2	5.7767	8.5487	2.3604	1.69
EW-1	GDSC1; GDSC2	5.8321	8.0405	2.5847	0.7975
MG-63	GDSC1; GDSC2; CTRP2	5.8671	8.5302	4.6508	6.209
NOS-1 [Human HNSCC]	GDSC1; GDSC2	5.997	8.1446	2.6133	0.6155
SaOS-2	GDSC1; GDSC2; CTRP2	6.0335	6.9206	5.5972	1.901
EW-7	GDSC1; GDSC2	6.0582	7.7666	2.7715	0.2278
EW-22	GDSC2	6.0713	18.6106	-2.1697	21.6857
EW-3	GDSC1; GDSC2	6.0936	8.1815	2.6379	0.5025
Hs 822.T	CTRP2	6.2652	8.0292	5.2295	3.0222
ES7	GDSC1; GDSC2	6.3417	16.8292	-1.1107	17.3518
EW-11	GDSC1; GDSC2	6.3684	8.9488	2.4648	0.8491
HuO-3N1	GDSC1; GDSC2	6.5086	8.584	2.6512	0.3193
ES4	GDSC1; GDSC2	6.8341	9.0964	2.5914	0.3355

Cancer Drug Sensitivity Data Curated from 222 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JK1	CTRP2	4.4141	7.2992	3.8153	13.0812
MEC1	CTRP2	4.8734	9.9623	3.0407	15.0443
JM1	GDSC1; GDSC2; CTRP2	4.6025	6.5694	4.3016	10.692
NK-92MI	GDSC1; GDSC2	-4.542	2.3117	-5.0069	68.4376
OCI-M1	GDSC1; GDSC2; CTRP2	-2.815	-0.1394	-2.8167	58.9765
SET-2	CTRP2	-2.6108	0.2243	-2.614	57.6105
TF-1	CTRP2	-1.5168	4.7602	-1.8955	50.3232
M-07e	CTRP2	-0.9379	7.6752	-2.076	47.4137
CMK	CTRP2	-0.4874	4.1313	-0.6674	43.8823
Pfeiffer	CTRP2	0.4906	13.6809	-3.0145	42.8333
MJ	CTRP2	0.531	12.5613	-2.4721	42.1607
F-36P	CTRP2	0.7408	9.5916	-0.9882	39.3972
CRO-AP2	GDSC2	0.8892	7.6917	-1.1167	33.4656
L-1236	GDSC1; GDSC2; CTRP2	0.9579	23.5286	-7.2295	44.3852
YT	GDSC1	1.0882	18.1626	-6.6061	41.584
A3/Kawakami	GDSC1; GDSC2; CTRP2	1.1964	5.6759	0.8496	33.4097
DND-41	GDSC1; GDSC2; CTRP2	1.3211	53.956	-21.9531	47.1235
ATN-1	GDSC1; GDSC2	1.3233	43.396	-18.4041	46.1337
SUP-HD1	GDSC1; GDSC2; CTRP2	1.3644	10.6071	-0.7611	36.8372
HEL	GDSC1; GDSC2; CTRP2	1.3726	6.2848	0.8783	32.716
Karpas-45	GDSC1; GDSC2	2.0139	9.7861	-1.0559	28.8256
HDLM-2	GDSC1; GDSC2; CTRP2	2.057	10.7544	-0.1135	33.1936
SUP-M2	GDSC1; GDSC2; CTRP2	2.2299	2.995	2.2299	25.4127
TUR	GDSC1; GDSC2	2.2665	6.6554	0.7106	19.6508
MOLM-16	GDSC2; CTRP2	2.3217	4.0839	2.3064	24.8525
SUP-B8	GDSC2	2.3657	5.1173	1.541	14.3936
SU-DHL-1	GDSC1; GDSC2; CTRP2	2.395	3.1078	2.395	24.3127
MOLM-13	GDSC1; GDSC2; CTRP2	2.5765	6.507	2.1241	24.6868
HEL 92.1.7	CTRP2	2.6726	8.0961	1.655	26.0535
BC-3	GDSC1; GDSC2	2.7531	6.9874	0.9959	16.3217
EoL-1	GDSC1; GDSC2; CTRP2	2.8522	4.2808	2.8427	21.2984
OCI-AML-5	GDSC1; GDSC2; CTRP2	2.9905	5.0257	2.9243	20.57
MV4-11	GDSC1; GDSC2; CTRP2	3.058	6.685	2.5902	21.5566
Ki-JK	CTRP2	3.1287	4.0292	3.128	19.4273
DEL	GDSC1; GDSC2; CTRP2	3.1555	4.8671	3.1182	19.3717
Karpas-299	GDSC1; CTRP2	3.1614	5.3857	3.0504	19.5866
KMS-28BM	CTRP2	3.2494	11.4211	0.7785	27.2829
AML-193	CTRP2	3.359	7.2206	2.7255	20.1793
JVM-2	GDSC1; GDSC2	3.3643	5.316	2.36	5.9683
BONNA-12	GDSC2	3.4208	6.5227	1.8032	9.3212
SR	GDSC1; GDSC2; CTRP2	3.4743	6.9894	2.9346	19.0665
Jiyoye	GDSC1; GDSC2	3.5175	5.355	2.4634	4.8929
KMS-34	CTRP2	3.6159	10.8968	1.3843	24.3514
Karpas-1106P	GDSC2	3.6608	6.4596	2.0258	7.2689
GDM-1	GDSC1; GDSC2; CTRP2	3.6712	9.7137	1.9886	22.0757
SU-DHL-16	GDSC1; GDSC2	3.8483	5.2346	2.7607	2.2829
Loucy	GDSC1; GDSC2	3.8629	12.2448	-0.6971	21.5535
JSC-1	GDSC1; GDSC2	3.8632	19.2021	-4.1717	31.8488
EM-2	GDSC1; GDSC2; CTRP2	3.8694	5.9988	3.6831	15.1403
U-937	CTRP2	3.8984	6.6932	3.4978	15.7355
ML-2	GDSC1; GDSC2	3.9257	8.9951	0.9715	12.9806
JURL-MK1	GDSC1; GDSC2; CTRP2	4.0047	6.0279	3.8229	14.224
KMS-26	CTRP2	4.0171	12.4533	1.0257	24.509
CTV-1	GDSC1; GDSC2	4.0459	10.1219	0.5049	15.2638
SU-DHL-6	GDSC1; GDSC2; CTRP2	4.0836	6.7405	3.6809	14.5153
DG-75	GDSC1; GDSC2	4.0985	6.4403	2.3528	4.2114
OCI-Ly7	GDSC2	4.1304	5.9331	2.6128	2.612
MEG-01	GDSC1; GDSC2	4.1772	6.8457	2.2118	4.8951
CTB-1	GDSC1; GDSC2	4.1816	6.4253	2.4149	3.6716
QIMR-WIL	GDSC1; GDSC2	4.2263	6.6596	2.3332	4.0664
KY821	GDSC1; GDSC2	4.2383	7.3828	1.9951	6.0736
ARH-77	GDSC1; GDSC2	4.2764	10.4544	0.5165	14.5986
Hs 445	GDSC1; GDSC2	4.2794	6.0264	2.6597	2.0929
Sc-1	GDSC1	4.3077	6.0813	1.7934	0.8963
H9	GDSC1; GDSC2	4.3154	13.8698	-1.1487	22.1694
Farage	GDSC1; GDSC2	4.3544	6.4185	2.526	2.7108
KMS-12-BM	GDSC1; GDSC2; CTRP2	4.3745	5.9184	4.2548	11.5405
ROS-50	GDSC1; GDSC2	4.3813	7.2935	2.1345	4.9355
BE-13	GDSC1; GDSC2	4.4125	6.6987	2.4326	3.138
GA-10	GDSC2; CTRP2	4.4179	5.91	4.3042	11.2307
DoHH2	GDSC2	4.4202	6.0109	2.7448	1.4407
KG-1	GDSC1; GDSC2	4.4227	9.31	1.1884	10.4712
NCO2	CTRP2	4.4653	6.429	4.2026	11.4594
NALM-6	GDSC1; GDSC2; CTRP2	4.4659	7.0476	3.9724	12.3312
Kasumi-1	GDSC1; GDSC2; CTRP2	4.4932	7.907	3.6354	13.5794
HuNS1	CTRP2	4.5472	7.5185	3.8611	12.5466
OCI-AML-2	GDSC1; GDSC2; CTRP2	4.5832	7.3486	3.9711	12.0191
Mono-Mac-6	GDSC1; CTRP2	4.5916	12.2715	1.6504	21.0025
Peer	CTRP2	4.6356	6.5717	4.3364	10.4665
KMS-21-BM	CTRP2	4.6371	7.1522	4.11	11.3317
EB2	GDSC1; GDSC2	4.6601	8.8566	1.5748	7.6718
SKM-1	GDSC2; CTRP2	4.6669	5.9215	4.5728	9.5032
SU-DHL-5	GDSC1; GDSC2	4.6835	5.952	2.8951	0.5234
ALL-SIL	GDSC1; GDSC2	4.6884	7.8729	2.0594	4.7787
P32/ISH	GDSC1; GDSC2	4.6994	6.199	2.805	0.8545
BDCM	CTRP2	4.7325	20.1394	-2.1241	30.7608
697	GDSC1; GDSC2; CTRP2	4.7328	6.4965	4.4683	9.6911
P30/OHK	GDSC1; GDSC2	4.7337	7.9106	2.0703	4.6322
EB1	CTRP2	4.7469	7.4002	4.1182	11.0078
MY-M12	GDSC1; GDSC2	4.7484	8.8455	1.6394	7.1077
KMS-11	GDSC1; GDSC2; CTRP2	4.7546	8.2856	3.7263	12.555
LAMA-84	GDSC1; GDSC2; CTRP2	4.7616	7.0998	4.2621	10.4034
ST486	GDSC1; GDSC2; CTRP2	4.7765	6.7561	4.4175	9.7611
Ramos.2G6.4C10	GDSC1; GDSC2	4.7888	6.6867	2.6476	1.4568
AMO1	GDSC1; GDSC2; CTRP2	4.7979	7.1957	4.2592	10.3181
KE-97	CTRP2	4.8141	6.8762	4.4094	9.689
IM-9	GDSC2	4.8225	6.1596	2.8748	0.4978
BALL-1	GDSC1; GDSC2	4.8539	9.3602	1.4643	7.9068
Mono-Mac-1	CTRP2	4.8571	8.4358	3.757	12.1794
RPMI-8866	GDSC1; GDSC2	4.8753	7.1986	2.4738	2.1977
CA46	GDSC1; GDSC2; CTRP2	4.8988	7.2277	4.3498	9.695
JeKo-1	GDSC2; CTRP2	4.9023	6.9474	4.4729	9.2028
Jurkat	GDSC2; CTRP2	4.9091	6.5242	4.6477	8.5112
WSU-DLCL2	GDSC1; CTRP2	4.9259	6.3089	4.7425	8.1066
P12-Ichikawa	GDSC1; GDSC2; CTRP2	4.9337	6.5508	4.6643	8.3788
Ri-1	CTRP2	4.943	9.9411	3.1162	14.5797
JVM-3	GDSC1; GDSC2; CTRP2	4.9791	6.7764	4.6239	8.4075
L-540	GDSC1; GDSC2; CTRP2	4.9925	6.752	4.648	8.278
U-698-M	GDSC1; GDSC2	4.9968	7.36	2.4687	2.0635
Karpas-231	GDSC2	5.0044	6.3264	2.8868	0.3577
BL-41	GDSC1; GDSC2	5.0234	6.9589	2.6497	1.1963
MHH-PREB-1	GDSC1; GDSC2	5.0293	6.835	2.7024	0.9732
SK-MM-2	GDSC1; GDSC2	5.0312	7.2229	2.5445	1.6586
MOLM-6	CTRP2	5.0555	7.6103	4.3374	9.3436
MOLT-16	GDSC1; GDSC2; CTRP2	5.0631	6.6799	4.7516	7.684
A4/Fukuda	GDSC1; GDSC2; CTRP2	5.0649	6.3983	4.8615	7.2597
WSU-NHL	GDSC1; GDSC2	5.0825	6.6113	2.8124	0.5351
Mino	CTRP2	5.0885	7.0466	4.624	8.115
SU-DHL-8	GDSC1; GDSC2; CTRP2	5.0918	6.7077	4.7706	7.5323
BV-173	GDSC1; GDSC2; CTRP2	5.1045	9.2471	3.6052	12.2165
NKM-1	GDSC1	5.1111	6.9616	1.7893	0.4079
NU-DUL-1	GDSC1; GDSC2; CTRP2	5.1149	6.4462	4.8976	6.9807
CESS	GDSC1; GDSC2	5.1211	7.0544	2.6569	1.0746
KHM-1B	CTRP2	5.1612	6.4687	4.9388	6.6936
SUP-T1	GDSC1; GDSC2; CTRP2	5.2015	6.9637	4.7763	7.2174
P31/FUJ	GDSC1; CTRP2	5.2133	6.4923	4.9852	6.3707
HH [Human lymphoma]	GDSC1; GDSC2; CTRP2	5.2155	7.4838	4.5551	8.0681
MOTN-1	CTRP2	5.2215	12.8572	1.9301	18.5633
JJN-3	GDSC1; GDSC2; CTRP2	5.2243	6.8755	4.8382	6.9132
Daudi	GDSC1; GDSC2; CTRP2	5.2315	6.8149	4.8718	6.7619
KO52	CTRP2	5.2419	7.2207	4.7024	7.4085
OCI-AML-3	GDSC1; GDSC2; CTRP2	5.2568	6.1785	5.1448	5.6452
OCI-Ly19	GDSC1; GDSC2; CTRP2	5.2573	6.8456	4.8852	6.6408
Ku812	GDSC1; GDSC2; CTRP2	5.2618	7.2682	4.7007	7.3656
MOLP-8	GDSC1; GDSC2; CTRP2	5.2663	6.5042	5.0369	6.0254
RS4;11	GDSC1; GDSC2; CTRP2	5.285	6.8889	4.8948	6.5308
DB	GDSC1; GDSC2; CTRP2	5.2852	7.0424	4.8268	6.8008
NU-DHL-1	CTRP2	5.2889	6.7292	4.9679	6.232
SCC-3	GDSC1; GDSC2	5.3156	6.506	2.9396	0.1354
K-562	GDSC1; GDSC2; CTRP2	5.3387	7.0376	4.8829	6.4403
KCL-22	GDSC1; GDSC2; CTRP2	5.34	7.0841	4.8632	6.5161
NCI-H929	GDSC2; CTRP2	5.3614	6.2916	5.2194	5.0628
ME1	GDSC1; GDSC2	5.3692	6.6496	2.9094	0.1717
Hs 611.T	CTRP2	5.3767	7.799	4.5632	7.647
RPMI-6666	GDSC1; GDSC2; CTRP2	5.3817	8.5488	4.2046	9.1145
KMS-18	CTRP2	5.3925	11.512	2.7499	15.053
PF-382	GDSC1; GDSC2; CTRP2	5.3982	7.2059	4.865	6.364
L-428	GDSC1; GDSC2; CTRP2	5.4029	12.0693	2.4819	16.084
RPMI-8226	GDSC1; GDSC2; CTRP2	5.4084	6.8896	5.0202	5.7138
VAL	GDSC1; GDSC2	5.4117	9.7966	1.616	5.9764
KOPN-8	GDSC1; GDSC2	5.4245	7.7003	2.5381	1.2825
PL21	CTRP2	5.4318	6.7094	5.1241	5.24
HAL-01	GDSC1; GDSC2	5.4367	8.068	2.3936	1.8969
OCI-Ly3	CTRP2	5.4444	7.5632	4.7412	6.7576
THP-1	GDSC1; GDSC2; CTRP2	5.4485	7.026	4.9983	5.7011
U266B1	GDSC1; GDSC2; CTRP2	5.4646	6.7304	5.1485	5.0582
VL51	GDSC1; GDSC2	5.4667	11.7863	0.7161	10.7807
EHEB	CTRP2	5.4884	7.9759	4.5835	7.3051
RCH-ACV	GDSC2; CTRP2	5.4987	7.737	4.7093	6.7623
KMS-20	CTRP2	5.507	6.3734	5.344	4.1787
RPMI-8402	GDSC1; CTRP2	5.5107	6.6492	5.2315	4.6092
CML-T1	GDSC2; CTRP2	5.5122	6.4137	5.3333	4.2058
OPM-2	GDSC1; GDSC2; CTRP2	5.5235	8.0915	4.5599	7.3239
RC-K8	GDSC1; GDSC2	5.5397	6.7214	2.9448	0.0866
SU-DHL-4	GDSC1; GDSC2; CTRP2	5.5549	7.1301	5.0542	5.2143
MHH-CALL-2	GDSC2	5.559	7.0846	2.827	0.2724
KE-37	GDSC1; GDSC2; CTRP2	5.5615	6.2269	5.4583	3.5898
MOLT-3	CTRP2	5.5667	6.8832	5.1818	4.6671
SUP-B15	GDSC1; GDSC2; CTRP2	5.5867	6.5785	5.3405	3.9799
BL-70	CTRP2	5.5933	6.0321	5.5554	3.1373
NOMO-1	GDSC1; GDSC2; CTRP2	5.5961	6.1495	5.5229	3.2479
Reh	GDSC1; GDSC2; CTRP2	5.6079	6.2464	5.5009	3.2971
MC116	GDSC1; GDSC2; CTRP2	5.608	6.3179	5.4731	3.4034
Granta-519	GDSC1; GDSC2; CTRP2	5.6105	6.786	5.2703	4.2011
TK [Human B-cell lymphoma]	GDSC1; GDSC2	5.6125	7.1795	2.8134	0.2826
MOLT-13	GDSC1; GDSC2; CTRP2	5.6268	7.2346	5.0734	4.966
Karpas-422	GDSC1; GDSC2; CTRP2	5.6308	6.2472	5.525	3.1408
MM1.S	GDSC2; CTRP2	5.6338	6.2898	5.5116	3.1838
Raji	GDSC1; GDSC2; CTRP2	5.6375	6.1463	5.5689	2.9562
KYO-1	CTRP2	5.6408	6.2222	5.5452	3.0361
SIG-M5	GDSC1; GDSC2; CTRP2	5.6453	6.1879	5.5627	2.957
Namalwa	GDSC1; GDSC2; CTRP2	5.6535	6.516	5.4364	3.4262
Ci-1	CTRP2	5.6638	6.3993	5.4979	3.1561
LP-1	GDSC1; GDSC2; CTRP2	5.6829	8.8568	4.3266	7.9496
KM-H2	GDSC1; GDSC2; CTRP2	5.7107	13.9877	1.7914	18.0266
L-363	GDSC1; GDSC2; CTRP2	5.7286	6.2813	5.6151	2.5243
SEM	CTRP2	5.7332	7.0497	5.2636	3.9365
MHH-CALL-4	GDSC2; CTRP2	5.7338	9.5929	4.0051	9.1883
Kasumi-2	CTRP2	5.7366	6.2666	5.6296	2.4461
HD-MY-Z	CTRP2	5.7505	6.3526	5.6076	2.4954
SU-DHL-10	GDSC1; GDSC2; CTRP2	5.7636	6.3524	5.6212	2.407
MOLP-2	CTRP2	5.7647	6.5422	5.5362	2.7455
RL	GDSC1; GDSC2; CTRP2	5.7692	6.4062	5.603	2.4654
CCRF-CEM	GDSC1; GDSC2	5.779	7.3985	2.798	0.2592
Toledo	CTRP2	5.8034	8.2495	4.7352	5.9866
SUP-T11	CTRP2	5.8217	6.5998	5.5647	2.4916
HPB-ALL	CTRP2	5.8293	6.7505	5.4993	2.7432
HT	GDSC1; GDSC2; CTRP2	5.8399	6.7015	5.533	2.5797
MN-60	GDSC1; GDSC2	5.8605	7.5625	2.7705	0.288
ALL-PO	GDSC1; GDSC2	5.875	17.6484	-1.8411	21.0098
HC-1	GDSC1; GDSC2	5.9799	8.1073	2.6202	0.6049
PL-21	GDSC1; GDSC2	5.9834	12.6802	0.6314	10.1911
MHH-CALL-3	CTRP2	6.0077	8.5599	4.7559	5.4873
KMS-27	CTRP2	6.0896	9.2376	4.4853	6.4666
HL-60	GDSC1; GDSC2; CTRP2	6.1023	7.1245	5.5518	1.9613
ME1	CTRP2	6.1159	7.1204	5.5647	1.8823
TALL-1 [Human adult T-ALL]	GDSC2; CTRP2	6.1346	8.7058	4.7881	5.1091
EJM	GDSC1; GDSC2; CTRP2	6.1525	14.9823	1.6652	17.5847
KMOE-2	GDSC1; GDSC2	6.1858	7.728	2.8295	0.1181
P3HR-1	CTRP2	6.2378	7.9804	5.2325	3.0574
MOLT-4	GDSC1; GDSC2	6.241	15.4205	-0.5015	15.0445
OCI-Ly10	CTRP2	6.2959	7.9013	5.3163	2.608
LC4-1	GDSC1; GDSC2	6.308	8.1555	2.7271	0.2387
GR-ST	GDSC1; GDSC2	6.3088	8.3474	2.6604	0.3651
KMM-1	CTRP2	6.3143	10.7683	3.9034	8.4845
HuT 78	CTRP2	6.3596	25.0177	-3.1809	29.5568
Karpas-620	GDSC1; GDSC2; CTRP2	6.6191	8.1805	5.4089	1.7441
WIL2 NS	GDSC1; GDSC2	6.8756	22.6448	-3.5617	24.082
REC-1	CTRP2	7.552	12.0705	4.1763	5.3704
MLMA	GDSC1; GDSC2	7.9807	23.0937	-3.0024	20.5732
NB4	GDSC1; GDSC2; CTRP2	8.06	16.4523	2.4096	11.5061
BC-1	GDSC1; GDSC2	8.6324	25.702	-3.8114	21.6463

Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TE8	CTRP2	4.8492	8.9033	3.5279	13.1286
TE15	CTRP2	5.0526	7.2898	4.4798	8.7804
TE-6	GDSC1; GDSC2; CTRP2	4.6328	6.1959	4.4599	10.015
T.T	GDSC1	4.6914	6.4338	1.8184	0.5295
TE-15	GDSC1; GDSC2	5.1367	8.9928	1.8183	5.3365
KYSE-180	GDSC1; GDSC2; CTRP2	5.1883	6.6966	4.8766	6.8584
TE-8	GDSC1; GDSC2	5.1956	7.7015	2.4261	2.0234
OE21	GDSC1; GDSC2; CTRP2	5.287	7.2386	4.7394	7.1467
KYSE-410	GDSC1; GDSC2; CTRP2	5.3105	8.0844	4.3629	8.6249
TE-4	GDSC1; GDSC2; CTRP2	5.4147	9.4986	3.7681	10.8519
TE-11	GDSC1; GDSC2; CTRP2	5.4208	7.3483	4.8204	6.4901
TE-9	GDSC1; GDSC2; CTRP2	5.5301	6.268	5.4094	3.8644
KYSE-140	GDSC1; GDSC2; CTRP2	5.6086	6.9041	5.2133	4.437
KYSE-270	GDSC1; GDSC2	5.664	7.934	2.5536	1.0222
KYSE-70	GDSC1; GDSC2; CTRP2	5.7226	6.6553	5.442	3.2304
KYSE-510	GDSC1; GDSC2; CTRP2	5.7471	6.3587	5.6015	2.5285
TE-5	GDSC1; GDSC2; CTRP2	5.7518	6.6392	5.4781	3.0124
TE-14	CTRP2	5.7671	6.5334	5.5427	2.7133
OE33	GDSC1; GDSC2; CTRP2	5.7776	6.5759	5.5332	2.7261
KYSE-520	GDSC1; GDSC2; CTRP2	5.7864	7.0052	5.335	3.5203
TE-10	GDSC1; GDSC2; CTRP2	5.8099	7.1141	5.3034	3.5988
KYSE-450	GDSC1; GDSC2; CTRP2	5.8115	16.7395	0.5016	22.096
KYSE-150	GDSC1; CTRP2	5.9054	8.0659	4.9156	5.0202
EC-GI-10	GDSC1; GDSC2; CTRP2	5.9075	7.9868	4.9569	4.8422
KYSE-30	CTRP2	5.9277	7.0099	5.4613	2.6861
TE-1	GDSC1; GDSC2; CTRP2	5.945	6.8161	5.5729	2.1824
OE19	GDSC1; GDSC2; CTRP2	5.995	6.7201	5.6645	1.6948
COLO 680N	GDSC1; GDSC2; CTRP2	6.0116	6.8353	5.6212	1.843

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
N2a-PK1	CTRP2	5.7062	6.4597	5.5151	2.9771
BxPC-3	GDSC1; GDSC2; CTRP2	4.7164	6.7877	4.3412	10.2208
PL4	GDSC1; GDSC2	4.8684	6.9444	2.5793	1.4884
HuP-T4	GDSC1; GDSC2; CTRP2	5.2005	6.7034	4.8866	6.7865
SW1990	GDSC1; GDSC2; CTRP2	5.3609	6.381	5.1855	5.1926
KP-4	GDSC1; GDSC2; CTRP2	5.3658	6.6206	5.094	5.533
KP-1N	GDSC1; GDSC2	5.5123	8.1868	2.3815	1.6504
PSN1	GDSC1; GDSC2; CTRP2	5.5292	6.8484	5.1605	4.8459
PK-59	CTRP2	5.5406	7.2713	4.9733	5.5793
Panc 03.27	GDSC1; GDSC2; CTRP2	5.5454	6.0946	5.4853	3.5365
SNU-213	CTRP2	5.5588	7.5828	4.8406	6.0823
YAPC	GDSC1; GDSC2; CTRP2	5.6392	6.1078	5.5834	2.8975
HuP-T3	GDSC1; GDSC2; CTRP2	5.6636	6.6239	5.3979	3.5545
SU.86.86	GDSC1; GDSC2; CTRP2	5.7095	6.4415	5.5265	2.9231
Panc 08.13	GDSC1; GDSC2; CTRP2	5.71	6.4606	5.5186	2.9536
Panc 05.04	CTRP2	5.7215	6.2985	5.6006	2.6001
Capan-2	GDSC1; GDSC2; CTRP2	5.7218	6.5186	5.5043	2.9806
KP-3	GDSC1; GDSC2; CTRP2	5.7321	7.9953	4.7978	5.8753
Panc 10.05	GDSC1; GDSC2	5.7408	7.3656	2.7955	0.2441
MIA PaCa-2	GDSC1; GDSC2; CTRP2	5.746	6.3258	5.6145	2.48
HPAC	GDSC1; GDSC2; CTRP2	5.7668	6.3983	5.6041	2.4672
Panc 04.03	GDSC1; GDSC2; CTRP2	5.7856	6.6911	5.4863	2.8985
HPAF-II	GDSC1; GDSC2; CTRP2	5.7956	6.9384	5.3762	3.3289
DAN-G	GDSC1; GDSC2; CTRP2	5.796	6.5213	5.5768	2.5042
PaTu 8988t	GDSC1; GDSC2; CTRP2	5.8573	6.3926	5.6973	1.8653
Capan-1	GDSC1; GDSC2; CTRP2	5.9007	6.8841	5.4995	2.5838
PaTu 8988s	CTRP2	5.9643	7.0516	5.4726	2.5628
L3.3	CTRP2	5.9677	6.722	5.6397	1.8551
Hs 766T	GDSC1; GDSC2; CTRP2	5.9708	6.9287	5.5396	2.2683
QGP-1	GDSC1; GDSC2; CTRP2	5.9806	7.2301	5.3976	2.8442
KP-2	GDSC1; GDSC2; CTRP2	6.0118	6.9038	5.5872	1.9855
PaTu 8902	GDSC1; GDSC2; CTRP2	6.0503	6.7853	5.6788	1.5254
TCC-Pan2	CTRP2	6.057	7.0123	5.5709	1.9658
SUIT-2	GDSC1; GDSC2; CTRP2	6.0705	7.2571	5.4597	2.4077
AsPC-1	GDSC1; GDSC2; CTRP2	6.0955	7.3829	5.4173	2.5389
MZ-PC-1	GDSC1; GDSC2	6.1129	7.9499	2.7277	0.2583
CFPAC-1	GDSC1; GDSC2; CTRP2	6.1462	7.8503	5.2248	3.2534
Panc 02.03	GDSC1; GDSC2; CTRP2	6.2462	7.366	5.5433	1.7473
PK-45H	CTRP2	6.2475	8.4196	5.0215	3.9232
SNU-410	CTRP2	6.7288	9.356	4.9185	3.5635

Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SH4	CTRP2	5.7901	7.0533	5.3151	3.8609
DJM-1	GDSC1; GDSC2	4.528	6.7416	2.4819	2.6682
A-431	GDSC1; GDSC2	4.5532	6.4496	2.6258	1.864
CP66-MEL	GDSC1; GDSC2	4.7002	6.0935	2.8473	0.6858
MZ-MEL-7	GDSC1; GDSC2	4.8354	6.702	2.6644	1.3267
COLO 783	GDSC1; GDSC2	4.8675	6.7269	2.6699	1.2675
IST-MEL1	GDSC1	5.0538	7.0457	1.7375	0.5844
G-mel	GDSC1; GDSC2	5.0964	6.9241	2.6975	0.9344
RPMI-7951	GDSC1; GDSC2; CTRP2	5.1141	7.1642	4.5985	8.1496
MMAc-SF	GDSC1; GDSC2	5.1377	6.8584	2.7415	0.7377
VMRC-MELG	GDSC1; GDSC2	5.1623	6.5301	2.8744	0.3167
LB373-MEL-D	GDSC1; GDSC2	5.2428	6.6341	2.868	0.2988
WM35	GDSC1	5.2978	7.3902	1.7073	0.5486
CHL-1	GDSC1; GDSC2	5.3367	7.9166	2.407	1.9479
Hs 938.T	GDSC1; GDSC2	5.3689	6.8931	2.8232	0.3132
Hs 852.T	CTRP2	5.3711	7.7885	4.5629	7.6613
GAK	GDSC1; GDSC2	5.3933	7.2368	2.7055	0.6845
Hs 895.T	CTRP2	5.3989	6.7959	5.0524	5.61
LB2518-MEL	GDSC1; GDSC2	5.4481	6.6733	2.9293	0.1222
451Lu	GDSC1; GDSC2	5.5279	7.3022	2.7363	0.5111
RVH-421	GDSC1; GDSC2; CTRP2	5.5477	6.7148	5.2399	4.4806
A-388	GDSC1; GDSC2	5.558	7.2544	2.7657	0.4166
IGR-39	CTRP2	5.5706	7.3724	4.9536	5.5897
LOX-IMVI	GDSC1; GDSC2; CTRP2	5.5921	6.1779	5.5089	3.312
CP50-MEL-B	GDSC1; GDSC2	5.5999	7.0277	2.8618	0.1929
M14	GDSC1; GDSC2	5.6057	7.1797	2.8108	0.2906
G-361	GDSC1; GDSC2; CTRP2	5.6693	7.9538	4.7616	6.1625
WM1552C	GDSC1; GDSC2	5.6845	7.2002	2.8326	0.2218
MZ-MEL-2	GDSC1; GDSC2	5.7167	7.4585	2.7533	0.3788
CJM [Human melanoma]	CTRP2	5.7288	6.505	5.5175	2.9098
A-375	GDSC1; GDSC2; CTRP2	5.7549	6.5273	5.5334	2.7807
Hs 294T	CTRP2	5.7893	6.2518	5.691	2.0647
HT-144	GDSC1; GDSC2; CTRP2	5.8216	6.5318	5.5969	2.3601
SH-4	GDSC1; GDSC2	5.8321	8.1287	2.5512	0.9093
Hs 940.T	GDSC1; GDSC2; CTRP2	5.8462	6.8999	5.442	2.9424
WM88	CTRP2	5.847	6.5312	5.6218	2.198
COLO 829	GDSC1; GDSC2; CTRP2	5.8486	7.2175	5.2876	3.5803
MeWo	GDSC1; CTRP2	5.884	6.5512	5.6475	2.006
A101D	GDSC1; GDSC2; CTRP2	5.8853	6.55	5.6492	1.996
Hs 944.T	CTRP2	5.9198	6.7548	5.5807	2.2039
COLO 679	GDSC1; GDSC2	5.9232	7.5177	2.8089	0.1993
COLO 792	GDSC1; GDSC2; CTRP2	5.9407	6.9075	5.5237	2.3976
A2058	GDSC1; GDSC2; CTRP2	5.9427	6.5299	5.7124	1.6052
WM793	GDSC1; GDSC2; CTRP2	5.9434	6.6638	5.6469	1.8765
Mel JuSo	GDSC1; GDSC2; CTRP2	5.9436	6.8793	5.5402	2.3224
WM266-4	CTRP2	5.9461	6.5189	5.721	1.5617
IPC-298	GDSC1; GDSC2; CTRP2	6.0115	6.804	5.6368	1.7777
SK-MEL-5	GDSC1; GDSC2; CTRP2	6.0197	6.7672	5.6622	1.6548
UACC-62	GDSC1; GDSC2; CTRP2	6.02	6.8341	5.629	1.7936
MDA-MB-435S	CTRP2	6.0293	7.3088	5.3995	2.74
WM115	GDSC1; GDSC2; CTRP2	6.0834	7.0928	5.5524	1.9941
WT2-iPS	GDSC1; GDSC2; CTRP2	6.0839	6.9477	5.6252	1.6871
HMCB	CTRP2	6.1017	6.7548	5.7358	1.1908
Hs 688(A).T	CTRP2	6.1525	8.2099	5.0504	3.9743
UACC-257	GDSC1; GDSC2; CTRP2	6.194	7.0169	5.6765	1.2803
SK-MEL-2	GDSC1; GDSC2; CTRP2	6.1949	7.1641	5.6045	1.5781
WM1799	CTRP2	6.2277	7.1374	5.6421	1.3683
Hs 839.T	CTRP2	6.2374	7.5636	5.439	2.1958
SK-MEL-24	GDSC1; GDSC2; CTRP2	6.2662	7.3642	5.559	1.6501
WM278	GDSC1; GDSC2	6.3182	8.6581	2.5523	0.6225
Mel Ho	GDSC1; GDSC2; CTRP2	6.367	7.6385	5.4976	1.7454
IGR-1	GDSC1; GDSC2; CTRP2	6.3956	7.8468	5.4165	2.0335
HMV-II	GDSC1; GDSC2	6.5293	8.9767	2.519	0.6107
COLO 800	GDSC1; GDSC2; CTRP2	6.5379	8.0117	5.4354	1.7492
WM983B	CTRP2	6.5598	8.133	5.3921	1.8922
SK-MEL-3	GDSC1; GDSC2; CTRP2	6.5618	7.9267	5.4916	1.4941
SK-MEL-28	GDSC1; GDSC2; CTRP2	6.5982	7.6316	5.651	0.8415
IGR-37	GDSC1; GDSC2; CTRP2	6.6425	17.874	0.6204	20.1003
K029AX	CTRP2	6.6871	7.9222	5.5717	1.0361
SK-MEL-1	GDSC1; CTRP2	6.8202	8.74	5.2753	2.0063
SK-MEL-31	GDSC2; CTRP2	6.9847	8.5411	5.4652	1.1099
SK-MEL-30	GDSC1; GDSC2; CTRP2	7.5974	8.632	5.7094	0.1139
Hs 934.T	CTRP2	7.6177	8.9775	5.5915	0.3123
Hs 936.T	CTRP2	7.744	9.0842	5.6031	0.2431
COLO 741	CTRP2	7.82	19.5494	0.7085	17.7259
EquiPSC Line K2	GDSC1; GDSC2	4.6432	7.3204	2.2871	3.56

Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HCE-4	GDSC1; GDSC2	4.26	6.8184	2.2801	4.3145
ESO-51	GDSC1; GDSC2	5.0289	7.9608	2.2232	3.2851
ESO-26	GDSC1; GDSC2	5.8231	7.6757	2.7161	0.4247
SK-GT-4	GDSC1; GDSC2	5.9881	8.0105	2.6589	0.4963
FLO-1	GDSC1; GDSC2	6.0284	8.4158	2.5247	0.8678
KYSE-50	GDSC1; GDSC2	6.0931	7.693	2.8092	0.1607
TE-12	GDSC1; GDSC2	6.099	9.4441	2.1485	2.2819
OACM5.1 C	GDSC1; GDSC2	6.1719	8.9078	2.3973	1.2063
KYAE-1	GDSC1; GDSC2	6.4609	17.7794	-1.4874	18.5347
OACP4 C	GDSC1; GDSC2	6.5182	8.6862	2.6189	0.3805
KYSE-220	GDSC1; GDSC2	6.5241	8.643	2.6362	0.3435

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
COLO 684	GDSC1; GDSC2; CTRP2	4.7757	8.3076	3.7369	12.4598

Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KP-N-RT-BM-1	GDSC2	3.656	6.638	1.9334	7.8597
SK-N-MC-IXC	GDSC1; GDSC2	3.6792	4.9341	2.7907	2.4559
CHP-126	GDSC2; CTRP2	3.9085	7.1029	3.3581	16.2343
NB1	CTRP2	3.9586	5.7299	3.8456	14.2856
SJNB-14	GDSC1; GDSC2	4.0327	5.95	2.5426	3.2101
GOTO	GDSC1; GDSC2	4.0412	6.7377	2.17	5.4464
IMR-5	GDSC1; GDSC2	4.0982	7.8514	1.6671	8.3936
SJNB-5	GDSC1; GDSC2	4.4486	6.4381	2.5724	2.3007
KP-N-SI9s	CTRP2	4.5691	8.9692	3.2242	15.0317
MHH-NB-11	GDSC1; GDSC2; CTRP2	4.5851	6.9698	4.1298	11.3967
CHP-212	GDSC1; GDSC2; CTRP2	4.7463	13.2323	1.3186	21.792
SJNB-12	GDSC1	4.8528	7.0467	1.656	1.0159
CHP-134	GDSC1; GDSC2	4.956	6.7168	2.716	0.9838
KP-N-YS	GDSC1; GDSC2	5.1053	7.3783	2.5165	1.7038
SJNB-7	GDSC1; GDSC2	5.2026	7.1295	2.6642	0.9746
NB69	GDSC1; GDSC2	5.2341	7.5255	2.5189	1.5517
SJNB-13	GDSC1; GDSC2	5.3625	7.3311	2.6561	0.8775
NB(TU)1	GDSC1; GDSC2	5.3763	6.8939	2.8258	0.3453
NH-12	GDSC1; GDSC2	5.4188	7.2247	2.7208	0.6194
SK-N-BE(2)-M17	GDSC1; GDSC2	5.4505	6.9659	2.8283	0.3091
SiMa	GDSC1; GDSC2	5.4643	8.0103	2.431	1.6994
TGW	GDSC1; GDSC2	5.4825	6.9891	2.8321	0.2885
LA-N-6	GDSC1; GDSC2	5.5398	7.2317	2.7669	0.422
SK-N-BE(2)	CTRP2	5.6912	8.785	4.3697	7.7518
SK-N-SH	GDSC1; CTRP2	5.7077	6.9394	5.2926	3.8763
Kelly	GDSC1; GDSC2; CTRP2	5.7186	6.2787	5.6057	2.5878
SK-N-DZ	GDSC1; GDSC2; CTRP2	5.782	6.8426	5.4099	3.2207
NH-6	CTRP2	5.7926	8.9563	4.3736	7.5243
SK-N-AS	GDSC1; GDSC2; CTRP2	5.8116	6.449	5.626	2.2664
SK-N-FI	GDSC1; CTRP2	5.833	6.5566	5.5961	2.3364
SJNB-10	GDSC1; GDSC2	5.8444	8.0638	2.581	0.8018
SJNB-6	GDSC1; GDSC2	5.8763	7.4842	2.8036	0.2205
SJNB-17	GDSC1; GDSC2	5.9836	8.2039	2.5859	0.703
GI-ME-N	GDSC1; GDSC2	6.4741	14.9377	-0.1158	12.864
KP-N-YN	GDSC1; GDSC2; CTRP2	7.2232	12.1994	3.8854	7.0251

Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuH-28	CTRP2	4.1451	8.4567	3.036	16.8468
SNU-478	CTRP2	4.9463	6.3867	4.7377	8.0655
HuCC-T1	GDSC1; GDSC2	5.104	7.106	2.6281	1.2096
SNU-308	CTRP2	5.6619	6.8855	5.2741	4.0605
SNU-1079	CTRP2	5.787	6.6889	5.4887	2.8853
SNU-1196	CTRP2	5.978	6.7428	5.6384	1.8392
SNU-869	CTRP2	6.0421	6.8877	5.6208	1.7847

Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MFM-223	GDSC1; GDSC2	3.7974	9.1594	0.7893	14.3678
HCC1187	GDSC1; GDSC2	3.9842	5.9318	2.5191	3.4495
EFM-192A	GDSC1; GDSC2	4.0451	5.9221	2.5638	3.0595
HCC1599	GDSC1; GDSC2	4.1035	5.9925	2.5682	2.9208
MDA-MB-175-VII	GDSC1	4.2347	5.9598	1.8088	0.6907
Evsa-T	GDSC1; GDSC2	4.4783	5.8734	2.8324	0.9559
EFM-19	GDSC1; GDSC2	4.588	6.7149	2.5283	2.3243
MDA-MB-157	GDSC1; GDSC2; CTRP2	4.6251	6.7517	4.2578	10.7942
HCC1954	GDSC1; GDSC2; CTRP2	4.8828	6.7853	4.5186	9.0787
HCC2157	GDSC1; GDSC2	4.9149	7.4201	2.3987	2.528
AU565	GDSC1; GDSC2	5.057	7.9429	2.247	2.7518
BT-483	GDSC1	5.1138	6.4972	1.949	0.1033
CAL-51	GDSC1; GDSC2; CTRP2	5.1535	6.5111	4.9143	6.8088
BT-474	GDSC1; GDSC2	5.1604	6.754	2.791	0.5552
UACC-893	GDSC1; GDSC2	5.3759	7.5998	2.5559	1.1073
Hs 578T	GDSC1; GDSC2; CTRP2	5.3793	6.8034	5.029	5.7537
MRK-nu-1	GDSC1; GDSC2	5.4402	7.2147	2.7333	0.568
OCUB-M	GDSC1; GDSC2	5.5468	7.5605	2.6471	0.7778
HCC1395	GDSC1; CTRP2	5.5736	7.1217	5.0764	5.0791
MDA-MB-231	GDSC1; GDSC2; CTRP2	5.6559	8.1204	4.6671	6.5855
HCC70	GDSC1; GDSC2	5.6592	7.1597	2.8375	0.1943
HCC1806	GDSC1; GDSC2; CTRP2	5.6658	6.2955	5.5432	2.974
MDA-MB-468	GDSC1; GDSC2; CTRP2	5.6751	6.3743	5.5202	3.0384
MDA-MB-415	GDSC1; GDSC2	5.7236	7.4739	2.7504	0.338
DU4475	GDSC1; GDSC2; CTRP2	5.7255	6.2624	5.6196	2.5152
YMB-1-E	GDSC1; GDSC2	5.7525	7.8831	2.6111	0.7627
ZR-75-1	CTRP2	5.7705	6.3355	5.6357	2.3321
HDQ-P1	GDSC1; GDSC2; CTRP2	5.775	6.667	5.4876	2.918
MDA-MB-453	GDSC1; GDSC2; CTRP2	5.7853	8.965	4.3629	7.5839
CAL-85-1	GDSC1; GDSC2; CTRP2	5.792	6.6961	5.4901	2.8677
COLO 824	GDSC1; GDSC2	5.7939	8.4079	2.4251	1.4078
CAL-148	GDSC1; CTRP2	5.8006	6.5589	5.5636	2.5466
HMC-1-8	CTRP2	5.803	6.5339	5.5778	2.4828
BT-549	GDSC1; GDSC2; CTRP2	5.8446	6.6684	5.5534	2.4847
MCF-7	GDSC1; GDSC2; CTRP2	5.903	6.9321	5.4778	2.6692
BT-20	GDSC1; GDSC2; CTRP2	5.9184	6.9486	5.4834	2.6132
HCC1143	GDSC2; CTRP2	5.9297	7.4956	5.2211	3.6885
HCC202	GDSC1; CTRP2	5.945	7.3769	5.2936	3.3531
HCC38	GDSC1; GDSC2; CTRP2	5.9816	7.5666	5.2304	3.5448
HCC1500	GDSC1; GDSC2; CTRP2	5.9862	7.0254	5.5046	2.3838
MDA-MB-436	GDSC1; GDSC2	6.1121	7.7436	2.7986	0.1518
HCC1569	GDSC1; GDSC2	6.1394	8.911	2.3818	1.2878
HCC2218	GDSC1; GDSC2; CTRP2	6.1894	7.7511	5.3086	2.824
JIMT-1	GDSC1; GDSC2; CTRP2	6.1948	7.3616	5.5065	1.9868
CAMA-1	GDSC1; GDSC2; CTRP2	6.2196	7.8912	5.2626	2.963
T-47D	GDSC1; GDSC2; CTRP2	6.2256	7.4653	5.4787	2.0502
HCC1428	GDSC1; GDSC2; CTRP2	6.2393	7.3063	5.5676	1.6577
CAL-120	GDSC1; GDSC2; CTRP2	6.3171	7.587	5.4869	1.8666
HCC1937	GDSC1; GDSC2; CTRP2	6.3488	7.919	5.3471	2.3933
MDA-MB-330	GDSC1; GDSC2	6.4148	8.5879	2.615	0.4258
ZR-75-30	GDSC1; GDSC2; CTRP2	6.4755	8.2826	5.2611	2.5479
UACC-812	GDSC1; CTRP2	6.5582	8.921	5.0086	3.4567
Hs 578Bst	CTRP2	6.6346	8.6093	5.2142	2.5015
HCC1419	GDSC1; GDSC2; CTRP2	7.0686	8.5986	5.486	0.9594
KPL-1	CTRP2	7.2383	19.6227	0.2227	20.2002
MDA-MB-361	GDSC1; GDSC2; CTRP2	7.4385	9.4866	5.2993	1.2558
BT 416	CTRP2	5.6477	7.574	4.9282	5.5178
BT147	CTRP2	5.7246	8.0329	4.7725	5.9974
BT 428	CTRP2	5.7609	7.3242	5.1552	4.3235
BT 228	CTRP2	5.9583	6.7765	5.6044	2.0227
BT 139	CTRP2	5.9619	6.6194	5.6855	1.6758
BT 239	CTRP2	5.9739	7.964	5.0252	4.4219
BT 172	CTRP2	5.9918	6.7826	5.6306	1.8434
BT 231	CTRP2	6.025	6.9912	5.5548	2.0957
BT 112	CTRP2	6.0733	6.8966	5.6421	1.636
BT164	CTRP2	6.0773	6.7978	5.6947	1.4074
BT 330	CTRP2	6.1013	6.9096	5.6582	1.5168
BT 145	CTRP2	6.12	6.9348	5.6605	1.4734
BT 504	CTRP2	6.1477	7.3051	5.4979	2.1051
BT 216	CTRP2	6.1544	7.9707	5.1713	3.463
BT 444	CTRP2	6.1583	7.0647	5.6258	1.5515
BT 286	CTRP2	6.1749	14.293	2.0284	16.2251
BT 131	CTRP2	6.1834	7.257	5.5496	1.8264
BT 179	CTRP2	6.1945	8.0908	5.1434	3.507
BT 422	CTRP2	6.2158	7.9476	5.2316	3.0995
BT 333	CTRP2	6.2879	7.6087	5.4548	2.0462
BT 159	CTRP2	6.2945	7.4759	5.5249	1.7459
BT 482	CTRP2	6.312	7.7087	5.4234	2.1369
BT 498	CTRP2	6.3448	7.4966	5.5508	1.5616
BT 248	CTRP2	6.369	7.7292	5.4548	1.9174
BT 271	CTRP2	6.468	31.6142	-6.3892	33.8535
BT 359	CTRP2	6.4846	7.9551	5.4264	1.8608
BT 245	CTRP2	6.4851	8.0256	5.3927	1.9965
BT 224	CTRP2	6.5613	7.8357	5.5341	1.3283
BT 340	CTRP2	6.6985	19.8076	-0.3	22.6535
BT 232	CTRP2	6.7267	8.1889	5.4734	1.3587
BT 328	CTRP2	7.2799	11.9311	4.0563	6.2455
BT 440	CTRP2	7.5827	17.1173	1.7318	14.7351
BT 187	CTRP2	7.9751	10.1318	5.2977	0.8561
BT 320	CTRP2	12.005	27.5087	-0.2196	14.4555

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
YD-38	CTRP2	5.8387	6.4514	5.6516	2.0963

Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Central Nervous System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
AM-38	GDSC1; GDSC2	3.5275	6.2467	2.0271	7.6165
MOG-G-CCM	GDSC1	3.7025	6.1264	1.4687	3.6592
D-423MG	GDSC1; GDSC2	4.0276	6.423	2.3128	4.066
Onda 10	GDSC1; GDSC2	4.3138	6.2022	2.6004	2.3642
M059J	GDSC1; GDSC2	4.326	7.0992	2.1902	4.7159
MOG-G-UVW	GDSC1	4.4001	12.8351	-1.2672	18.9097
KINGS-1	GDSC1; GDSC2	4.4826	9.9977	0.895	12.0054
D-245MG	GDSC2	4.5041	8.5636	1.6089	7.8085
D-336MG	GDSC1; GDSC2	4.6733	7.5397	2.2045	3.9743
KS-1 [Human Krukenberg tumour]	GDSC1; GDSC2	4.7046	6.9866	2.4732	2.4427
KNS-60	CTRP2	4.7957	6.829	4.409	9.7408
LNZTA3WT4	GDSC1	4.8467	6.3265	1.914	0.2164
D-542MG	GDSC1; GDSC2	4.8526	6.2712	2.8449	0.5786
D-502MG	GDSC1; GDSC2	4.8962	6.8701	2.6246	1.4412
D-392MG	GDSC1; GDSC2	5.0553	8.4486	2.0186	4.3589
PFSK-1	GDSC1; GDSC2	5.1884	7.768	2.3941	2.1866
GI-1	GDSC1; GDSC2	5.1983	8.3795	2.1327	3.51
SF539	GDSC1; GDSC2; CTRP2	5.258	7.2803	4.6913	7.4128
D-263MG	GDSC1; GDSC2	5.3719	7.0607	2.7629	0.5179
SK-MG-1	GDSC1; GDSC2	5.3805	6.7829	2.867	0.2204
D-566MG	GDSC1; GDSC2	5.4261	7.1579	2.7488	0.5298
42-MG-BA	GDSC1; GDSC2; CTRP2	5.4307	7.1959	4.9018	6.1351
GB-1	GDSC1; GDSC2; CTRP2	5.4544	7.7028	4.6837	6.97
LN-405	GDSC1; GDSC2	5.4742	6.9792	2.8325	0.2907
LN-18	GDSC1; GDSC2; CTRP2	5.4788	6.318	5.3356	4.2897
CAS-1	GDSC1; GDSC2; CTRP2	5.5163	7.4047	4.8862	5.9936
YH-13	GDSC1; GDSC2; CTRP2	5.5427	6.2257	5.4385	3.7185
Daoy	GDSC1; GDSC2; CTRP2	5.5644	7.32	4.9728	5.5253
SW1088	GDSC1; GDSC2; CTRP2	5.5709	7.2835	4.9965	5.4128
A-172	GDSC1; GDSC2; CTRP2	5.576	6.6437	5.3005	4.1664
D283 Med	GDSC1; GDSC2; CTRP2	5.5788	7.6083	4.8471	6.0097
M059K	CTRP2	5.6149	6.8067	5.2651	4.2114
Hs 683	GDSC1; GDSC2; CTRP2	5.6497	6.2852	5.5303	3.0682
SF268	GDSC1; GDSC2; CTRP2	5.652	7.316	5.0579	4.9716
Becker	GDSC1; GDSC2; CTRP2	5.6828	7.276	5.1063	4.7012
SF126	GDSC1; GDSC2; CTRP2	5.7044	7.0067	5.2571	4.0298
D-247MG	GDSC1; GDSC2	5.7191	7.4834	2.7453	0.3972
SNU-738	CTRP2	5.7788	8.891	4.3942	7.4665
SNU-466	CTRP2	5.7957	6.5606	5.558	2.5812
GMS-10	CTRP2	5.7984	6.7101	5.4895	2.855
YKG-1	GDSC1; GDSC2; CTRP2	5.7998	7.211	5.2465	3.8579
SNU-1105	CTRP2	5.8037	6.6917	5.5034	2.7855
U-118MG	GDSC1; GDSC2; CTRP2	5.8218	7.3208	5.2123	3.9524
KALS-1	GDSC1; GDSC2; CTRP2	5.856	7.2781	5.2642	3.6621
TM-31	CTRP2	5.8846	7.0796	5.3882	3.0828
SF295	GDSC1; GDSC2; CTRP2	5.8873	7.6078	5.1282	4.1654
LN-229	GDSC1; GDSC2; CTRP2	5.9336	7.056	5.4435	2.7481
ONS-76	GDSC1; GDSC2; CTRP2	5.9538	7.694	5.143	3.9674
DK-MG	GDSC1; GDSC2; CTRP2	5.9812	6.8318	5.5969	2.0064
SNU-626	CTRP2	6.0036	7.1621	5.4512	2.5733
T98G	GDSC1; GDSC2; CTRP2	6.0048	7.1076	5.4795	2.452
U-87MG ATCC	GDSC1; GDSC2; CTRP2	6.0218	6.783	5.6561	1.6761
GaMG	GDSC1; GDSC2; CTRP2	6.0241	7.1532	5.473	2.4412
KG-1-C	CTRP2	6.0294	6.8693	5.6193	1.8158
Onda 11	GDSC1; GDSC2	6.1117	11.824	1.1095	7.4813
CCF-STTG1	CTRP2	6.1409	6.9788	5.6549	1.46
DBTRG-05MG	GDSC1; GDSC2; CTRP2	6.1947	7.4184	5.4782	2.1051
SNU-489	CTRP2	6.2075	8.2837	5.0576	3.8436
GOS-3	CTRP2	6.2092	7.1828	5.606	1.5478
H4	GDSC1; GDSC2	6.2307	7.8346	2.8092	0.1349
SW1783	GDSC1; CTRP2	6.25	8.4615	5.0026	3.9979
KNS-81-FD	GDSC1; GDSC2	6.2503	8.576	2.5555	0.6477
SNB-75	GDSC1; GDSC2; CTRP2	6.2957	7.657	5.4367	2.1085
KNS-81	CTRP2	6.3192	7.4183	5.5708	1.5186
8-MG-BA	GDSC1; GDSC2; CTRP2	6.3695	8.6291	5.012	3.7511
U-251MG	GDSC1; GDSC2; CTRP2	6.4133	8.0554	5.3273	2.3724
KNS-42	GDSC1; GDSC2; CTRP2	6.4235	10.5336	4.1074	7.4356
NMC-G1	GDSC1; GDSC2; CTRP2	6.462	8.1132	5.3339	2.2703
SNU-201	CTRP2	6.8932	10.5583	4.4498	5.2302

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TGBC1TKB	GDSC1	4.7903	6.6464	1.7798	0.5984
TGBC24TKB	GDSC1; GDSC2	5.4871	9.7507	1.6826	5.481
ETK-1	GDSC1; GDSC2	6.1285	8.7379	2.4441	1.0717

Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JHUEM-2	CTRP2	3.5447	7.0508	2.9879	18.6649
RL95-2	GDSC1; GDSC2; CTRP2	4.0339	5.731	3.9272	13.7622
AN3-CA	GDSC1; GDSC2; CTRP2	4.6334	6.765	4.2615	10.757
HEC-265	CTRP2	4.8033	6.8834	4.395	9.7738
HEC-6	CTRP2	5.2077	7.3259	4.62	7.8258
JHUEM-7	CTRP2	5.3677	7.4414	4.7248	7.0077
HEC-151	CTRP2	5.5202	6.1608	5.4367	3.7902
ESS-1	GDSC1; GDSC2; CTRP2	5.5419	6.8786	5.1593	4.8191
JHUEM-1	CTRP2	5.5637	6.104	5.5023	3.4196
MFE-280	GDSC1; GDSC2	5.573	10.4264	1.4244	6.743
KLE	GDSC1; GDSC2; CTRP2	5.599	6.4862	5.3935	3.7381
HEC-1-B	CTRP2	5.6184	7.6705	4.8538	5.8923
HEC-59	CTRP2	5.66	6.9032	5.264	4.1063
EN	GDSC1; GDSC2; CTRP2	5.8225	6.5877	5.5712	2.4632
HEC-108	CTRP2	5.8587	6.6186	5.5909	2.2976
MFE-296	GDSC1; GDSC2; CTRP2	5.8749	6.7091	5.562	2.3804
HEC-1-A	CTRP2	5.9469	6.7363	5.6142	2.0057
MFE-319	GDSC1; GDSC2; CTRP2	6.0372	6.978	5.5716	2.0011
HEC-50B	CTRP2	6.0376	7.3093	5.4063	2.6953
JHUEM-3	CTRP2	6.0423	7.7823	5.1737	3.664
HEC-251	CTRP2	6.0722	7.0659	5.5566	1.9974
EFE-184	CTRP2	6.0873	7.08	5.5619	1.9466
Ishikawa (Heraklio) 02 ER-	CTRP2	5.9858	6.5113	5.7605	1.3112

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KTCTL-140	GDSC1; GDSC2	3.4564	5.3616	2.4118	5.383
A-704	GDSC1; GDSC2	4.2607	6.3033	2.522	2.8976
KTCTL-1M	GDSC1; GDSC2	4.545	6.6368	2.5387	2.3338
CAL-54	GDSC1; GDSC2; CTRP2	4.8573	9.4456	3.2756	14.1336
LB996-RCC	GDSC1; GDSC2	4.8632	7.453	2.3554	2.4996
LB2241-RCC	GDSC1; GDSC2	4.9109	7.107	2.5321	1.6434
KTCTL-21	GDSC1; GDSC2	4.9494	7.9084	2.201	3.5292
TUHR4TKB	CTRP2	5.0813	6.4384	4.8644	7.2019
SW13	GDSC1; GDSC2	5.1071	6.7418	2.7732	0.5727
SN12C	GDSC1; GDSC2	5.1995	7.1484	2.6553	0.8933
SW156	GDSC1; GDSC2	5.2118	8.4432	2.112	3.1804
NCC021	GDSC1; GDSC2	5.216	7.1164	2.6753	0.9209
BB65-RCC	GDSC1; GDSC2	5.2444	7.1792	2.6633	0.8328
NCC010	GDSC2	5.3048	7.9708	2.368	2.1695
769-P	GDSC1; GDSC2; CTRP2	5.3484	8.2805	4.304	8.7794
UO-31	GDSC1; GDSC2; CTRP2	5.4567	6.8967	5.0657	5.4092
RXF 393L	GDSC1; GDSC2	5.4703	7.6271	2.588	0.9238
HA7-RCC	GDSC1; GDSC2	5.4979	7.5103	2.6455	0.721
KTCTL-26A	GDSC1; GDSC2	5.5327	7.5084	2.661	0.7406
BFTC-909	GDSC1; GDSC2; CTRP2	5.5518	7.3848	4.9296	5.7321
KMRC-1	GDSC1; CTRP2	5.5533	6.1483	5.4768	3.5445
KTCTL-13	GDSC1; GDSC2	5.5541	7.4027	2.7096	0.5747
OS-RC-2	GDSC1; GDSC2; CTRP2	5.5763	7.2553	5.0152	5.323
KMRC-20	GDSC1; GDSC2; CTRP2	5.831	6.8353	5.4595	2.9038
A-498	GDSC1; GDSC2; CTRP2	5.8499	6.6936	5.5463	2.502
KTCTL-195	GDSC1; GDSC2	5.8522	7.6487	2.7369	0.3634
SNU-1272	CTRP2	5.8561	7.6877	5.061	4.5121
786-O	GDSC1; GDSC2; CTRP2	5.8664	6.616	5.5995	2.2447
KMRC-2	CTRP2	5.8804	9.1892	4.3333	7.5149
KMRC-3	CTRP2	5.9697	7.6138	5.1966	3.7103
VMRC-RCZ	GDSC1; GDSC2; CTRP2	5.99	7.7972	5.1223	3.9823
VMRC-RCW	GDSC1; GDSC2; CTRP2	5.995	7.3603	5.3449	3.0371
LB1047-RCC	GDSC1; GDSC2	6.015	8.1092	2.6334	0.4862
TUHR10TKB	CTRP2	6.1062	7.9292	5.153	3.6294
Caki-2	CTRP2	6.1675	7.8731	5.2305	3.191
ACHN	GDSC1; GDSC2; CTRP2	6.245	9.0116	4.7245	5.1729
Caki-1	GDSC1; GDSC2; CTRP2	6.7984	8.3511	5.4424	1.3921
RCC10RGB	GDSC1; GDSC2; CTRP2	6.8086	8.3685	5.4406	1.387
TK-10	GDSC1; GDSC2	6.846	8.7482	2.7145	0.1298
TUHR14TKB	CTRP2	9.0716	11.1693	5.3628	0.2614

Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Large Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H716	GDSC1; GDSC2; CTRP2	4.1379	8.2013	3.1421	16.4491
SW48	GDSC1; GDSC2; CTRP2	4.675	6.3711	4.4494	9.9293
KM12	GDSC1; GDSC2; CTRP2	4.7138	9.2622	3.2261	14.6735
DiFi	GDSC2	5.0143	7.4074	2.4576	2.0959
CaR-1	GDSC1; GDSC2	5.063	7.6555	2.3763	2.4376
SW948	GDSC1; GDSC2; CTRP2	5.1076	8.2381	4.0944	10.2032
SW626	GDSC1; GDSC2	5.1755	7.6937	2.4191	2.0817
SNU-175	GDSC1; GDSC2; CTRP2	5.253	7.1522	4.7447	7.2112
SK-CO-1	GDSC2; CTRP2	5.2657	6.3315	5.1019	5.779
SW1116	GDSC1; GDSC2	5.3343	7.1614	2.7094	0.7109
SW1463	GDSC1; GDSC2	5.3547	6.7989	2.8516	0.2927
LoVo	GDSC1; GDSC2; CTRP2	5.413	6.7407	5.0911	5.4199
SNU-C5	GDSC1; GDSC2; CTRP2	5.4152	7.3748	4.8025	6.5763
SNU-81	GDSC1; GDSC2	5.4213	7.118	2.7616	0.4951
LS180	GDSC1; GDSC2; CTRP2	5.4487	6.2505	5.3283	4.4023
HCC2998	GDSC1; GDSC2	5.4735	7.3131	2.7102	0.6196
SW620	GDSC1; GDSC2; CTRP2	5.4988	6.8541	5.1275	5.0553
GP5d	GDSC1; GDSC2	5.5138	7.1798	2.7756	0.4113
SNU-C2A	CTRP2	5.5267	8.3954	4.4138	7.923
COLO 320HSR	GDSC1; GDSC2	5.5479	13.4754	-0.0407	14.4098
COLO201	CTRP2	5.5742	8.4133	4.4484	7.6748
CCK-81	GDSC1; GDSC2; CTRP2	5.5875	6.4456	5.3989	3.7475
SNU-407	GDSC1; GDSC2; CTRP2	5.6238	6.3439	5.4793	3.3362
CW-2	GDSC1; GDSC2; CTRP2	5.6387	6.5953	5.3858	3.666
HCT 15	GDSC1; GDSC2; CTRP2	5.6522	6.3195	5.5192	3.1041
SNU-1040	GDSC1; GDSC2	5.6587	6.8629	2.9382	0.0768
MDST8	GDSC1; GDSC2; CTRP2	5.6589	6.0997	5.6073	2.7512
RKO	GDSC1; GDSC2; CTRP2	5.7535	6.8592	5.3749	3.431
LS123	GDSC1; GDSC2; CTRP2	5.7591	6.3948	5.5979	2.5116
SNU-283	GDSC2	5.7748	7.4811	2.7673	0.3242
GP2d	CTRP2	5.7858	6.568	5.5449	2.6587
SW837	GDSC1; GDSC2	5.7858	7.6712	2.7032	0.4742
HCT 116	GDSC1; GDSC2; CTRP2	5.7894	6.5497	5.557	2.6004
CL-11	GDSC1; GDSC2; CTRP2	5.8072	7.016	5.3491	3.415
LS513	GDSC1; GDSC2; CTRP2	5.8131	7.1481	5.2896	3.649
HT-29	GDSC1; GDSC2; CTRP2	5.8356	6.4503	5.649	2.1142
T84	GDSC1; GDSC2; CTRP2	5.8371	6.8391	5.4633	2.8745
COLO205	GDSC1; GDSC2; CTRP2	5.8654	6.4297	5.6879	1.8842
HT-55	GDSC1; GDSC2; CTRP2	5.8889	6.5509	5.6522	1.9756
SNU-61	GDSC1; GDSC2; CTRP2	5.8891	6.7235	5.5681	2.3235
LS411N	GDSC1; GDSC2; CTRP2	5.9069	6.5925	5.6487	1.949
RCM-1 [Human ESC]	GDSC1; GDSC2; CTRP2	5.9119	6.5987	5.6503	1.9312
HCT 8	CTRP2	5.918	6.5038	5.7024	1.7014
HT115	GDSC1; GDSC2; CTRP2	5.9214	7.9745	4.975	4.7382
COLO 678	GDSC1; GDSC2; CTRP2	5.9328	6.8765	5.532	2.3794
DLD-1	CTRP2	5.9456	6.5647	5.698	1.6588
HCC-56	CTRP2	5.981	6.6585	5.683	1.6461
C2BBe1	GDSC1; GDSC2; CTRP2	5.9951	7.0475	5.5011	2.3805
LS1034	GDSC1; GDSC2; CTRP2	6.0906	7.0892	5.56	1.9484
SNU-C4	CTRP2	6.0981	18.5903	-0.1839	23.4894
OUMS-23	CTRP2	6.1457	6.8832	5.7061	1.2379
SNU-503	CTRP2	6.1618	9.295	4.5159	6.2015
NCI-H508	GDSC2; CTRP2	6.1711	7.2395	5.5489	1.8506
SNU-C2B	GDSC1; GDSC2	6.1784	10.1949	1.8727	3.4739
SW1417	GDSC1; GDSC2; CTRP2	6.2158	7.5427	5.4328	2.2582
NCI-H747	GDSC1; GDSC2; CTRP2	6.3443	7.8079	5.3984	2.1886
SNU-C1	GDSC1; GDSC2; CTRP2	6.8163	13.9725	2.7038	12.4509

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MO-T	GDSC1; GDSC2	5.3637	7.516	2.5839	1.1523

Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Hep-G2/C3A	GDSC1; GDSC2	3.8343	5.8161	2.4717	4.0634
JHH-7	GDSC1; GDSC2	3.9657	7.5297	1.7275	7.3809
Li-7	CTRP2	4.2937	9.4911	2.709	17.7525
HLE	GDSC1; GDSC2	4.9588	7.1075	2.5565	1.4889
SNU-398	GDSC1; GDSC2; CTRP2	5.1169	7.063	4.646	7.9539
SNU-182	CTRP2	5.3956	22.6224	-2.7913	30.6527
Huh-7	GDSC1; GDSC2	5.4069	7.0758	2.7714	0.4747
SNU-423	GDSC1; GDSC2; CTRP2	5.4884	6.7257	5.1748	4.8923
Hep 3B2.1-7	GDSC1; GDSC2; CTRP2	5.5047	7.2439	4.9516	5.7536
JHH-5	CTRP2	5.6632	6.6528	5.3842	3.6103
JHH-1	GDSC1; GDSC2; CTRP2	5.6634	11.0845	3.2002	12.6677
PLC/PRF/5	CTRP2	5.6912	6.2811	5.5758	2.7784
SNU-449	GDSC1; GDSC2; CTRP2	5.7228	7.1664	5.1971	4.2352
HLF	CTRP2	5.746	6.2934	5.6283	2.4257
HuH-1	GDSC1; GDSC2; CTRP2	5.7643	6.6724	5.4746	2.9965
SNU-886	CTRP2	5.7652	7.7554	4.9464	5.1842
HuH-6	CTRP2	5.7798	8.7191	4.4806	7.1024
JHH-2	GDSC1; GDSC2; CTRP2	5.8006	7.5191	5.0952	4.4869
SNU-387	GDSC1; GDSC2; CTRP2	5.8064	7.2478	5.2344	3.8938
Hep-G2	CTRP2	5.8245	7.1229	5.3125	3.5292
SNU-761	CTRP2	5.8317	7.1021	5.3293	3.4433
SK-HEP-1	GDSC1; GDSC2; CTRP2	5.8782	6.5408	5.647	2.0217
JHH-6	GDSC1; GDSC2; CTRP2	6.0694	6.8168	5.6788	1.4892
SNU-878	CTRP2	6.0882	8.0862	5.0597	4.0552
SNU-475	GDSC1; CTRP2	6.1024	8.0153	5.1068	3.8304
JHH-4	GDSC1; GDSC2; CTRP2	10.05	18.9861	2.5291	8.3471

Cancer Drug Sensitivity Data Curated from 217 Cell Line(s) in Lung Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H1975	GDSC1; GDSC2; CTRP2	3.1932	5.0818	3.133	19.1992
HCC44	GDSC1; GDSC2; CTRP2	3.4602	6.0634	3.219	18.0602
NCI-H1304	GDSC1	3.5291	6.6826	1.1022	6.6609
NCI-H82	GDSC1; GDSC2	3.6183	5.8073	2.3167	5.5529
LK-2	GDSC1; GDSC2	3.6716	5.9331	2.2951	5.5525
COR-L303	GDSC1; GDSC2	3.7137	5.3384	2.6186	3.435
A-427	GDSC1; GDSC2	3.8248	5.8684	2.4395	3.7815
NCI-H1688	GDSC1	3.8377	6.353	1.4449	2.7481
NCI-H847	GDSC1	3.8797	9.626	-0.0746	13.7986
IST-SL1	GDSC1; GDSC2	4.0089	6.162	2.4256	3.9613
NCI-H345	GDSC1; GDSC2	4.0158	5.0663	2.9376	1.0097
NCI-H211	GDSC1; GDSC2; CTRP2	4.0281	6.7903	3.6031	14.9676
NCI-H64	GDSC1	4.0479	5.1354	2.0379	0.2132
COR-L23	GDSC1; GDSC2	4.0816	6.1926	2.4596	3.6057
RERF-LC-KJ	GDSC1; GDSC2	4.0868	5.8502	2.6241	2.6264
NCI-H2731	GDSC1; GDSC2	4.0978	6.1537	2.4887	3.4001
EMC-BAC-2	GDSC1; GDSC2	4.1338	6.7754	2.216	4.9624
NCI-H2171	GDSC1; GDSC2	4.1593	5.8224	2.6814	2.1705
IST-SL2	GDSC1; GDSC2	4.1767	7.5688	1.8618	7.0217
COR-L88	GDSC1	4.3676	6.3893	1.6997	1.2674
LC-2/ad	GDSC1; GDSC2	4.3824	9.0316	1.2954	9.941
NCI-H1755	GDSC1; GDSC2; CTRP2	4.3875	7.1408	3.852	13.0111
HARA [Human squamous cell lung carcinoma]	GDSC1; GDSC2; CTRP2	4.3887	6.4691	4.1059	12.0424
NCI-H2135	GDSC1; GDSC2	4.4604	6.8031	2.4138	3.1611
NCI-H2803	GDSC1; GDSC2	4.4779	7.2399	2.2221	4.2306
NCI-H146	GDSC2	4.4984	6.4133	2.6116	2.0163
NCI-H2228	GDSC1; GDSC2; CTRP2	4.5091	9.0377	3.1331	15.5431
EMC-BAC-1	GDSC1; GDSC2	4.5185	8.2614	1.7642	6.8541
NCI-H1876	GDSC1; GDSC2	4.5738	6.2606	2.7181	1.3776
PC-14	GDSC1; GDSC2; CTRP2	4.6037	6.6919	4.2577	10.8552
NCI-H647	GDSC1; GDSC2; CTRP2	4.61	8.0599	3.6852	13.0824
NCI-H2369	GDSC1; GDSC2	4.6281	6.1397	2.7954	0.9636
NCI-H2722	GDSC1; GDSC2	4.6281	7.4102	2.2366	3.8721
NCI-H838	GDSC1; GDSC2; CTRP2	4.6782	7.687	3.9217	11.965
NCI-H2795	GDSC1; GDSC2	4.6941	11.4649	0.3297	13.0706
NCI-H1563	GDSC1; GDSC2; CTRP2	4.6947	6.5308	4.4149	10.0017
SBC-3	GDSC1; GDSC2	4.7198	8.4653	1.8011	6.2208
NCI-H358	GDSC1; GDSC2; CTRP2	4.7403	8.6037	3.5637	13.2467
NCI-H720	GDSC1; GDSC2	4.7411	7.2796	2.3633	2.9765
Lu-99	CTRP2	4.7524	7.0238	4.284	10.343
NCI-H2810	GDSC2	4.7836	8.2833	1.9279	5.3594
HCC33	GDSC1; GDSC2	4.7894	6.6607	2.6588	1.4036
NCI-H1734	GDSC1; GDSC2; CTRP2	4.8125	6.6853	4.4833	9.4087
NCI-H748	GDSC1; GDSC2	4.8225	7.727	2.2087	3.6944
CAL-12T	GDSC1; GDSC2; CTRP2	4.8746	7.5708	4.1733	10.4587
NCI-H510A	GDSC1; GDSC2	4.8795	7.3456	2.412	2.5095
LXF 289	GDSC1; GDSC2; CTRP2	4.902	7.172	4.3772	9.5789
HCC2108	CTRP2	4.9085	8.0318	3.9966	11.0837
Ms-1	GDSC1; GDSC2	4.9109	6.7052	2.6996	1.0943
RERF-LC-MS	GDSC1; GDSC2; CTRP2	4.9346	7.1302	4.429	9.2885
NCI-H2347	GDSC1	4.9595	7.5589	1.504	1.5934
NCI-H290	GDSC1; GDSC2	4.9667	7.2311	2.5081	1.9085
NCI-H2009	GDSC1; CTRP2	5.0019	6.7459	4.6603	8.2046
COR-L321	GDSC1; GDSC2	5.0298	6.9188	2.669	1.1089
CPC-N	GDSC1; GDSC2	5.0441	6.8806	2.691	1.0057
NCI-H2373	GDSC1; GDSC2	5.0967	7.1313	2.6143	1.2753
Calu-3	GDSC1; GDSC2; CTRP2	5.1206	7.5523	4.4291	8.8121
COR-L311	GDSC1; GDSC2	5.1288	7.5807	2.4431	2.023
NCI-H1339	CTRP2	5.1447	7.762	4.3555	9.0502
Lu-134-A	GDSC1; GDSC2	5.1639	7.5061	2.4923	1.7491
NCI-H524	GDSC1; GDSC2	5.1994	7.5982	2.4716	1.8048
NCI-H3255	GDSC1; GDSC2	5.2238	7.7601	2.4157	1.8003
NCI-H1048	GDSC1; GDSC2	5.2248	7.1836	2.6527	1.0005
NCI-H2227	GDSC1; GDSC2	5.2318	7.6509	2.4657	1.7951
NCI-H2141	GDSC1; GDSC2	5.2515	13.26	-0.1452	15.5643
NCI-H1355	GDSC1; GDSC2; CTRP2	5.2558	8.3608	4.1776	9.5137
NCI-H23	GDSC1; GDSC2; CTRP2	5.259	6.9212	4.8539	6.7603
SW1271	GDSC1; GDSC2; CTRP2	5.2649	8.4958	4.1209	9.7266
NCI-H2030	GDSC1; GDSC2; CTRP2	5.2913	6.7541	4.9598	6.2574
HCC827	GDSC1; GDSC2; CTRP2	5.3005	9.6315	3.5986	11.8033
NCI-H1963	GDSC2	5.3108	10.2566	1.3389	7.7024
Lu-99A	GDSC1; GDSC2	5.3168	8.7981	2.0134	3.5046
DMS 79	GDSC1; GDSC2; CTRP2	5.3179	6.7235	5.0005	6.027
PaCa-3	GDSC1	5.3288	14.222	-1.2927	16.6808
NCI-H1435	GDSC1; GDSC2; CTRP2	5.3391	6.5313	5.103	5.5703
NCI-H250	GDSC2	5.3428	7.0871	2.7411	0.6015
NCI-H1581	GDSC1; GDSC2; CTRP2	5.3475	7.674	4.5949	7.5859
NCI-H1437	GDSC1; GDSC2	5.3663	8.7613	2.0578	3.6542
NCI-H1770	GDSC1; GDSC2	5.3826	6.8432	2.8464	0.2939
A-549	GDSC1; GDSC2; CTRP2	5.3862	7.7146	4.6128	7.4214
SHP-77	GDSC1; GDSC2; CTRP2	5.3869	6.5479	5.1465	5.2714
Lu-139	GDSC1; GDSC2	5.3955	9.8572	1.5782	6.2144
NCI-H1568	GDSC1; GDSC2; CTRP2	5.3961	12.6924	2.1658	17.3084
NCI-H1341	CTRP2	5.4072	6.613	5.1404	5.2408
HCC15	GDSC1; GDSC2; CTRP2	5.4366	7.3174	4.8505	6.3295
NCI-H1836	GDSC1; GDSC2	5.442	6.9036	2.8472	0.2701
NCI-H1838	GDSC1; CTRP2	5.4451	7.356	4.8405	6.3499
HCC366	GDSC2; CTRP2	5.4529	6.6938	5.1526	5.0724
NCI-H520	GDSC1; GDSC2; CTRP2	5.4727	6.5287	5.2442	4.6595
LUDLU-1	CTRP2	5.4748	6.9621	5.054	5.411
NCI-H1703	GDSC1; CTRP2	5.4863	6.2624	5.3645	4.1586
DV-90	CTRP2	5.4877	6.2598	5.3669	4.1456
COR-L51	CTRP2	5.4968	6.4035	5.3212	4.295
NCI-H2595	GDSC1; GDSC2	5.5046	8.1107	2.4092	1.7537
SK-MES-1	GDSC1; GDSC2; CTRP2	5.5087	6.4988	5.2944	4.3668
NCI-H727	GDSC1; GDSC2; CTRP2	5.522	6.9542	5.1046	5.0896
LC-1/sq-SF	CTRP2	5.5352	7.0484	5.0736	5.1831
NCI-H2286	CTRP2	5.5374	6.4577	5.3415	4.1059
NCI-H1993	GDSC1; GDSC2	5.5374	7.2367	2.7641	0.4302
MOR/CPR	CTRP2	5.5378	6.033	5.4946	3.526
EBC-1	GDSC1; GDSC2; CTRP2	5.5467	6.9632	5.1248	4.9471
NCI-H1781	GDSC1; GDSC2	5.5805	6.9296	2.8886	0.1537
NCI-H3122	GDSC1; GDSC2	5.5811	12.3106	0.5424	11.45
NCI-H2122	GDSC1; GDSC2; CTRP2	5.584	7.8618	4.7283	6.4896
NCI-H446	GDSC1; GDSC2; CTRP2	5.5933	7.8107	4.7619	6.3297
RERF-LC-A1	CTRP2	5.5959	7.1393	5.0896	4.972
EPLC-272H	GDSC1; GDSC2; CTRP2	5.6037	6.9225	5.1999	4.5031
NCI-H1573	GDSC1; CTRP2	5.6108	6.6032	5.354	3.8641
LOU-NH91	GDSC1; GDSC2; CTRP2	5.6221	8.3448	4.5257	7.2481
NCI-H2405	GDSC1; GDSC2; CTRP2	5.6293	8.9392	4.238	8.4332
NCI-H1915	GDSC1; GDSC2; CTRP2	5.6293	7.1563	5.1135	4.7954
NCI-H1155	GDSC1; GDSC2; CTRP2	5.6356	6.5928	5.3838	3.6818
NCI-H841	GDSC1; GDSC2; CTRP2	5.6425	7.0673	5.1688	4.5377
LCLC-97TM1	GDSC1; GDSC2; CTRP2	5.6494	6.5026	5.4381	3.4298
SBC-1	GDSC1; GDSC2	5.6535	7.1019	2.8555	0.1898
NCI-H2444	GDSC1; GDSC2; CTRP2	5.6546	6.4877	5.45	3.3692
NCI-H661	GDSC1; GDSC2; CTRP2	5.6749	6.8097	5.3226	3.8317
COR-L32	GDSC2	5.6773	7.9378	2.558	0.9964
NCI-H1648	GDSC1	5.68	7.7173	1.7336	0.3286
NCI-H2869	GDSC1; GDSC2	5.6971	11.2876	1.1016	8.2674
NCI-H522	GDSC1; GDSC2; CTRP2	5.6977	6.5082	5.4848	3.1199
NCI-H596	GDSC1; GDSC2	5.7009	15.3284	-0.8327	17.5894
NCI-H1436	GDSC1; GDSC2	5.7054	7.1471	2.8585	0.1719
NCI-H2172	GDSC1; GDSC2; CTRP2	5.708	7.4956	5.0224	4.9927
NCI-H1623	GDSC1; GDSC2; CTRP2	5.7176	6.595	5.465	3.1496
NCI-H1650	GDSC1; GDSC2; CTRP2	5.735	6.8892	5.3428	3.6059
COR-L105	GDSC1; GDSC2; CTRP2	5.7458	7.9856	4.815	5.7744
Calu-6	GDSC1; GDSC2; CTRP2	5.7591	7.0159	5.3043	3.7092
NCI-H810	GDSC1; GDSC2; CTRP2	5.7619	6.376	5.609	2.4601
HCC78	GDSC1; GDSC2; CTRP2	5.7624	6.612	5.5013	2.8928
ChaGo-K-1	GDSC1; GDSC2; CTRP2	5.766	6.5183	5.5486	2.6922
NCI-H1092	GDSC1; GDSC2; CTRP2	5.7724	6.7071	5.466	3.0127
Lu-165	GDSC1; GDSC2	5.7759	7.5547	2.7415	0.3828
NCI-H1373	CTRP2	5.7919	6.9688	5.358	3.4127
NCI-H1299	GDSC1; GDSC2; CTRP2	5.7938	6.9315	5.3779	3.3257
NCI-H1694	GDSC1; GDSC2; CTRP2	5.8057	6.7864	5.4596	2.9612
NCI-H2023	GDSC1; GDSC2; CTRP2	5.8213	6.7191	5.507	2.7299
NCI-H526	GDSC1; GDSC2; CTRP2	5.824	6.5066	5.6112	2.2961
UMC-11	GDSC1; GDSC2	5.8325	7.5333	2.7704	0.2625
NCI-H1184	CTRP2	5.8342	6.975	5.3941	3.1683
NCI-H2126	CTRP2	5.8393	6.6292	5.5674	2.4395
VMRC-LCD	GDSC2; CTRP2	5.8393	6.5996	5.5817	2.3808
NCI-H460	GDSC1; GDSC2; CTRP2	5.843	6.4292	5.6662	2.0266
NCI-H2591	GDSC1; GDSC2	5.8454	8.6865	2.3369	1.7226
NCI-H69	GDSC1; CTRP2	5.8568	7.2048	5.3013	3.5053
Lu-65	GDSC1; GDSC2; CTRP2	5.8586	6.7244	5.5394	2.511
DMS 53	GDSC1; GDSC2; CTRP2	5.8655	6.8935	5.4629	2.813
Lu-135	GDSC1; GDSC2	5.8719	7.7225	2.7179	0.3998
LK2	CTRP2	5.8721	6.266	5.7702	1.5348
HCC4006	CTRP2	5.876	7.8852	4.9801	4.8096
NCI-H1869	GDSC1; GDSC2; CTRP2	5.8898	7.737	5.0661	4.4206
NCI-H740	GDSC2	5.893	8.0283	2.6145	0.6685
SK-LU-1	GDSC1; GDSC2; CTRP2	5.9067	6.8254	5.534	2.4269
NCI-H2170	GDSC1; GDSC2; CTRP2	5.9097	6.895	5.5022	2.5529
NCI-H322	CTRP2	5.9144	6.7733	5.5667	2.2738
COLO 668	GDSC1; GDSC2; CTRP2	5.916	8.1264	4.8945	5.087
NCI-H889	CTRP2	5.9246	6.8967	5.5147	2.4688
NCI-H1105	GDSC2; CTRP2	5.9317	6.95	5.4946	2.5381
Sq-1	CTRP2	5.9345	7.8213	5.0628	4.3431
NCI-H441	GDSC1; GDSC2; CTRP2	5.9402	7.0097	5.4724	2.6131
NCI-H2081	GDSC1; GDSC2; CTRP2	5.9549	7.2223	5.3793	2.9731
SW1573	GDSC1; GDSC2; CTRP2	5.9641	8.5877	4.7052	5.786
IA-LM	GDSC1; GDSC2; CTRP2	5.9663	8.0816	4.9601	4.7108
NCI-H2029	GDSC1; GDSC2; CTRP2	5.9847	6.8594	5.5862	2.0444
T3M-10	CTRP2	5.9849	7.0767	5.4778	2.499
RERF-LC-Ad2	CTRP2	6.0031	6.7158	5.6737	1.6399
KNS-62	GDSC2; CTRP2	6.015	6.8497	5.617	1.8542
HCC1438	CTRP2	6.0151	6.7926	5.6456	1.7336
NCI-H1693	GDSC1; GDSC2; CTRP2	6.0218	7.4109	5.3422	2.9956
DMS 273	GDSC1; GDSC2; CTRP2	6.0252	6.9233	5.5888	1.9525
NCI-H226	GDSC1; GDSC2; CTRP2	6.0351	8.6595	4.7291	5.5465
NCI-H1793	GDSC1; GDSC2; CTRP2	6.0379	6.9415	5.5905	1.9205
LCLC-103H	GDSC1; GDSC2; CTRP2	6.0401	6.8147	5.6557	1.6421
ABC-1	GDSC1; GDSC2	6.0411	8.0831	2.6532	0.4871
NCI-H2106	CTRP2	6.046	7.8843	5.1258	3.8582
RERF-LC-Sq1	GDSC1; GDSC2	6.0507	10.0967	1.8474	3.7645
COR-L95	GDSC1; CTRP2	6.0604	7.0945	5.5326	2.1205
SBC-5	GDSC1; GDSC2; CTRP2	6.062	6.8425	5.6599	1.5825
NCI-H513	GDSC1; GDSC2	6.1062	8.2683	2.6113	0.5663
NCI-H1395	CTRP2	6.1069	8.466	4.8853	4.7527
NCI-H2804	GDSC1; GDSC2	6.1076	10.4687	1.7161	4.3442
HOP-62	GDSC1; GDSC2; CTRP2	6.126	7.3918	5.4375	2.3979
NCI-H650	GDSC1; GDSC2; CTRP2	6.1394	9.3441	4.473	6.4238
NCI-H1651	GDSC1; GDSC2; CTRP2	6.1483	7.3314	5.4853	2.1569
LB647-SCLC	GDSC1; GDSC2	6.1706	7.9107	2.7622	0.2149
NCI-H2085	GDSC1; GDSC2; CTRP2	6.1855	7.8785	5.2421	3.1098
DMS 114	GDSC1; GDSC2; CTRP2	6.2088	7.8172	5.291	2.8634
RERF-LC-Ad1	CTRP2	6.2422	7.3489	5.5488	1.7312
NCI-H2291	GDSC1; GDSC2; CTRP2	6.2499	7.6487	5.4064	2.3102
NCI-H2342	GDSC1; CTRP2	6.2628	8.0746	5.2051	3.1283
HCC1588	CTRP2	6.2637	8.2126	5.1372	3.4107
HOP-92	GDSC1; GDSC2; CTRP2	6.2833	8.4785	5.0203	3.865
HCC1171	CTRP2	6.3118	8.3304	5.1159	3.4162
DMS 454	CTRP2	6.3759	9.417	4.6258	5.3529
Calu-1	CTRP2	6.4148	7.9744	5.3679	2.2032
NCI-H2461	GDSC1; GDSC2	6.4347	8.4794	2.6606	0.3236
HCC95	CTRP2	6.4406	8.8217	4.9706	3.8042
NCI-H2818	GDSC1; GDSC2	6.4775	8.1745	2.7801	0.1141
NCI-H2196	GDSC1; GDSC2; CTRP2	6.5049	8.0016	5.4179	1.8662
COLO 699	CTRP2	6.5087	8.0831	5.3813	2.0084
LC-1/sq	GDSC1; GDSC2	6.7091	9.6961	2.3245	0.9575
NCI-H322M	GDSC1; GDSC2	6.7549	9.0444	2.5805	0.3807
BEN	GDSC1; GDSC2; CTRP2	6.9686	7.8345	5.7528	0.2403
NCI-H209	GDSC1; GDSC2	7.1181	23.6526	-3.8795	24.4244
EKVX	GDSC1; GDSC2; CTRP2	7.4807	9.8225	5.1755	1.6401
NCI-H2110	GDSC1; GDSC2; CTRP2	7.4903	15.7427	2.3412	12.6772
NCI-H1792	GDSC1; GDSC2; CTRP2	7.5851	16.2472	2.1632	13.1793
NCI-H1944	GDSC1; GDSC2; CTRP2	7.6029	15.5186	2.535	11.7618
HCC1833	CTRP2	7.7173	21.1908	-0.1838	20.5186
NCI-H292	GDSC1; GDSC2; CTRP2	8.6517	17.9085	2.1196	11.6673
NCI-H187	GDSC1	8.8463	24.898	-4.0462	19.7602
NCI-H2087	GDSC1; GDSC2; CTRP2	9.5355	23.131	0.2068	16.5408
NCI-H1666	GDSC1; GDSC2; CTRP2	9.6263	22.3121	0.6677	15.0448
HCC1195	CTRP2	10.1374	21.9514	1.1889	12.718
HCC2279	CTRP2	10.3106	24.0459	0.3031	15.1703
NCI-H196	GDSC1; GDSC2; CTRP2	10.5219	21.3846	1.7074	10.5492
Hs 888.Lu	CTRP2	5.3294	7.8727	4.4825	8.0892

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CBTCi002-A	GDSC1; GDSC2	6.3528	15.6418	-0.5319	14.9505

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
2004	CTRP2	5.1011	7.0862	4.6196	8.0994
A2780	GDSC1; GDSC2; CTRP2	4.8349	7.8002	4.0295	11.1347
OVKATE	GDSC1	4.9068	6.2918	1.9469	0.1439
ES-2	GDSC1; GDSC2	5.0821	7.3159	2.531	1.663
JHOS-4	GDSC2	5.1377	7.3745	2.5342	1.5865
Caov-3	GDSC1; GDSC2; CTRP2	5.4149	7.6488	4.6719	7.1115
OVCAR-3	GDSC1; GDSC2	5.4322	7.262	2.7123	0.638
Caov-4	GDSC1	5.4968	7.8538	1.6168	0.7202
JHOM-1	CTRP2	5.5099	6.8908	5.1217	5.0506
MCAS	CTRP2	5.5381	7.1477	5.0296	5.3553
COV434	CTRP2	5.5765	7.0175	5.1286	4.859
OVCAR-4	GDSC1; GDSC2; CTRP2	5.6054	6.3665	5.4506	3.4975
COV644	CTRP2	5.6113	6.347	5.4649	3.4258
OVK18	GDSC1; GDSC2; CTRP2	5.6253	6.1605	5.5507	3.0594
FU-OV-1	GDSC1; CTRP2	5.6735	7.0893	5.1878	4.3867
OV7	CTRP2	5.6917	6.8927	5.2996	3.8853
EFO-27	GDSC1; GDSC2; CTRP2	5.7053	7.0577	5.2333	4.1256
JHOS-2	GDSC1; GDSC2; CTRP2	5.7107	6.4074	5.5428	2.8556
OVTOKO	GDSC1; GDSC2; CTRP2	5.7213	8.6807	4.4482	7.3602
IGROV-1	GDSC1; GDSC2; CTRP2	5.725	8.306	4.6375	6.5603
HEY A8	CTRP2	5.7297	6.3377	5.5926	2.609
COV362	CTRP2	5.7328	6.9467	5.313	3.7338
TYK-nu	GDSC1; GDSC2; CTRP2	5.7557	6.4349	5.5764	2.606
EFO-21	GDSC1; GDSC2; CTRP2	5.7888	6.4528	5.6015	2.4221
SK-OV-3	GDSC1; GDSC2; CTRP2	5.7907	6.8214	5.4284	3.1245
OV-90	GDSC1; GDSC2; CTRP2	5.8042	6.5013	5.5943	2.4132
OVCAR-8	GDSC1; GDSC2; CTRP2	5.8362	6.7451	5.5084	2.6899
SNU-8	CTRP2	5.8419	6.4176	5.6706	2.0114
DOV13	GDSC1; GDSC2; CTRP2	5.846	6.6315	5.5726	2.4026
TOV-112D	GDSC1; GDSC2; CTRP2	5.8476	6.8137	5.4856	2.7585
JHOC-5	CTRP2	5.8504	6.4031	5.6857	1.9294
OVCAR-5	GDSC1; GDSC2; CTRP2	5.8581	7.4526	5.1796	4.0113
OAW42	GDSC1; GDSC2; CTRP2	5.8652	6.4034	5.7001	1.8347
OC 314	GDSC1; CTRP2	5.8758	6.6298	5.6015	2.2149
Kuramochi	GDSC1; GDSC2; CTRP2	5.8945	7.5313	5.1726	3.9646
ES2	CTRP2	5.9174	6.5592	5.6748	1.8172
ONCO-DG-1	CTRP2	5.9328	6.7052	5.6169	2.0248
TOV-21G	GDSC1; GDSC2; CTRP2	5.9358	6.8241	5.5607	2.2529
SNU-840	CTRP2	5.9404	10.1795	3.8896	9.2547
OV56	GDSC1; GDSC2; CTRP2	6.0242	6.6857	5.7068	1.4586
RMG-I	GDSC1; CTRP2	6.0287	7.4539	5.3265	3.0479
OVSAHO	CTRP2	6.0405	6.8303	5.6482	1.6728
OAW28	GDSC1; GDSC2; CTRP2	6.1534	7.4511	5.4297	2.3811
SNU-119	CTRP2	6.1733	9.4135	4.466	6.3894
OVISE	GDSC1; GDSC2; CTRP2	6.2664	13.428	2.536	14.1223

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SYO-1	CTRP2	5.1482	7.1066	4.6587	7.8222
H-STS	CTRP2	5.6983	6.1503	5.6333	2.5394
P-STS	CTRP2	6.5385	8.086	5.4002	1.8894

Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Yamato-SS	CTRP2	5.8312	6.8063	5.4738	2.8442
Aska-SS	CTRP2	10.4291	23.6608	0.568	14.2342
SW684	GDSC1; GDSC2	3.9169	6.2936	2.298	4.9438
GCT	GDSC1; GDSC2; CTRP2	4.1862	6.3806	3.9156	13.3417
Hs 633.T	GDSC1	4.4154	5.8718	1.9147	0.381
SW872	GDSC1; GDSC2	4.47	6.8033	2.4195	3.1122
TE 617.T	CTRP2	4.5544	6.745	4.1848	11.2712
STS-0421	GDSC1; GDSC2	4.5744	8.171	1.845	6.2577
VA-ES-BJ	GDSC1; GDSC2	4.6744	6.441	2.6931	1.3764
MFH-ino	GDSC1	4.7343	6.5749	1.7838	0.6187
A-204	GDSC1; GDSC2; CTRP2	4.8548	6.9636	4.4163	9.5513
SW982	GDSC1; GDSC2; CTRP2	5.0151	7.0581	4.5432	8.6266
Rh41	GDSC1; GDSC2; CTRP2	5.1472	6.976	4.7151	7.6016
TTC-709	CTRP2	5.2721	6.4292	5.0723	5.8736
TE 441.T	GDSC1; GDSC2; CTRP2	5.3683	7.1592	4.857	6.4705
HT-1080	GDSC1; GDSC2; CTRP2	5.4022	6.8908	5.0134	5.7571
G-401	GDSC1; GDSC2; CTRP2	5.4152	7.0163	4.9696	5.8997
G-402	GDSC1; GDSC2; CTRP2	5.6118	9.1034	4.141	8.8758
EW-8	GDSC1; GDSC2	5.6481	7.2154	2.814	0.2693
KYM-1	GDSC1; GDSC2; CTRP2	5.6789	6.1837	5.6004	2.7189
Hs 729.T	CTRP2	5.6853	6.7645	5.3541	3.6781
Tm87-16	CTRP2	5.6885	6.2098	5.6009	2.6897
SK-LMS-1	GDSC1; GDSC2; CTRP2	5.689	7.2538	5.1229	4.6185
MES-SA	GDSC1; GDSC2; CTRP2	5.7002	6.1692	5.6286	2.5517
BT-16	CTRP2	5.7593	6.3449	5.6201	2.4231
RKN	GDSC1; GDSC2; CTRP2	5.8394	6.3593	5.6949	1.9193
Rh18	GDSC1; CTRP2	5.8513	8.055	4.8739	5.3059
Rh30	GDSC1; GDSC2	5.8743	7.5641	2.7751	0.2744
RD	GDSC1; GDSC2; CTRP2	5.8849	6.9387	5.4583	2.7898
SK-UT-1	GDSC1; GDSC2; CTRP2	5.9796	6.9873	5.5179	2.3415

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
U-CH1	CTRP2	5.9529	7.0903	5.4434	2.7084

Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H2452	GDSC1; CTRP2	4.7896	8.3902	3.7121	12.5258
NCI-H28	GDSC1; GDSC2; CTRP2	4.8107	6.8231	4.4272	9.6291
MSTO-211H	GDSC1; GDSC2; CTRP2	5.4372	7.6542	4.6906	6.9821
IST-Mes1	GDSC1; GDSC2; CTRP2	5.6933	7.6862	4.9153	5.4701
ACC-MESO-1	CTRP2	5.8487	7.004	5.3931	3.1402
MPP 89	GDSC1; GDSC2; CTRP2	5.9483	7.6204	5.1749	3.8445
JL-1	CTRP2	5.9693	11.403	3.3022	11.6329
NCI-H2052	GDSC1; GDSC2; CTRP2	10.604	20.7494	2.0552	9.2996

Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H660	GDSC2	4.9347	6.7115	2.7082	1.0355
VCaP	GDSC1; GDSC2; CTRP2	5.3635	6.9243	4.9592	6.072
LNCaP clone FGC	GDSC1; GDSC2; CTRP2	5.5656	6.7585	5.2382	4.4425
DU145	GDSC1; GDSC2; CTRP2	5.7515	7.0542	5.2786	3.8328
PC-3	GDSC1; GDSC2	5.8493	8.6573	2.3506	1.6616
22Rv1	GDSC1; GDSC2; CTRP2	5.8655	6.9047	5.4573	2.8362
PaCa-3	CTRP2	6.1314	6.9146	5.6795	1.3736

Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
YD-15	CTRP2	4.8281	8.7297	3.59	12.9274
A-253	GDSC1; GDSC2; CTRP2	5.9885	6.9978	5.5203	2.3131

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuTu 80	GDSC1; GDSC2	3.7549	5.6019	2.5195	3.9516

Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KATO III	GDSC2; CTRP2	3.5622	8.2459	2.5283	20.3547
TMK-1	GDSC1; GDSC2	3.8985	6.2421	2.31	4.9121
SNU-16	GDSC1; CTRP2	4.2258	5.7774	4.1257	12.461
HSC-39	GDSC1	4.2293	8.3204	0.7811	7.2484
HGC-27	GDSC1; GDSC2; CTRP2	4.5351	5.6329	4.4886	10.2139
GCIY	GDSC1; GDSC2	4.6151	6.4186	2.6722	1.549
TGBC11TKB	GDSC1; GDSC2	4.758	6.754	2.6033	1.706
RF-48	GDSC1; GDSC2	4.7643	6.9533	2.5206	2.1109
OCUM-1	GDSC1; GDSC2; CTRP2	4.9527	7.227	4.4055	9.3341
RERF-GC-1B	GDSC1; GDSC2	5.0042	8.5885	1.9236	4.9793
SK-GT-2	GDSC2	5.0871	7.8428	2.3078	2.7544
Hs 746.T	GDSC1; GDSC2; CTRP2	5.2481	6.3015	5.0937	5.8604
SNU-620	CTRP2	5.3005	6.0059	5.2428	5.1569
MKN28	GDSC1; GDSC2	5.3008	7.6485	2.5006	1.5629
Fu97	GDSC1; CTRP2	5.3195	6.4714	5.1063	5.6115
GSS	CTRP2	5.4733	6.5834	5.2215	4.7468
SNU-719	CTRP2	5.482	6.5185	5.2582	4.5796
SNU-1	GDSC1; GDSC2; CTRP2	5.5239	6.7113	5.2174	4.6315
NUGC-4	GDSC1; GDSC2; CTRP2	5.5423	6.2875	5.4151	3.8082
SCH	GDSC1; GDSC2	5.5767	7.1858	2.7977	0.3306
23132/87	GDSC1; GDSC2; CTRP2	5.5912	6.2108	5.4962	3.3621
NUGC-3	GDSC1; GDSC2; CTRP2	5.6253	6.2514	5.5176	3.1843
SNU-668	CTRP2	5.6674	11.5006	2.9961	13.4886
SNU-5	GDSC1; GDSC2; CTRP2	5.6802	7.3154	5.0847	4.7968
LMSU	CTRP2	5.7048	11.7374	2.9101	13.7577
NCI-N87	GDSC1; GDSC2; CTRP2	5.7326	6.9461	5.3131	3.7337
IM95	GDSC1; GDSC2; CTRP2	5.736	6.6987	5.4347	3.2276
MKN74	CTRP2	5.8553	7.8056	5.0016	4.7625
ECC10	GDSC1; GDSC2; CTRP2	5.8635	6.6823	5.5645	2.3959
KE-39	CTRP2	5.8777	12.3446	2.7543	14.0284
AGS	GDSC1; GDSC2; CTRP2	6.0324	7.0217	5.5458	2.1191
GSU	CTRP2	6.0383	6.7128	5.7051	1.4379
HuG1-N	CTRP2	6.065	7.3795	5.3939	2.6946
MKN7	GDSC1; GDSC2; CTRP2	6.0655	7.3507	5.4088	2.6314
SNU-216	CTRP2	6.0806	7.0682	5.5624	1.9572
SNU-601	CTRP2	6.0867	6.9317	5.6355	1.639
SH-10-TC	CTRP2	6.0878	6.8666	5.6689	1.4967
ECC12	GDSC2; CTRP2	6.2423	7.5173	5.4656	2.0765
MKN1	GDSC1; GDSC2; CTRP2	6.2545	10.6589	3.9098	8.5681
MKN45	GDSC1; GDSC2; CTRP2	7.0979	8.0466	5.7267	0.2404
SNG-M	GDSC1; GDSC2; CTRP2	5.6959	7.1124	5.1979	4.2932
SNU-685	CTRP2	5.827	8.7729	4.4949	6.945
SNU-1077	CTRP2	6.6003	9.4766	4.7667	4.3885

Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
IHH-4	GDSC1; GDSC2	4.1142	5.6773	2.7207	1.7896
CAL-62	GDSC1; GDSC2	4.3613	6.9797	2.2697	4.1758
KMH-2	GDSC1; GDSC2	4.389	5.9571	2.7514	1.2791
WRO	GDSC1; GDSC2	5.3011	6.7136	2.8617	0.2903
TT	GDSC1; CTRP2	5.3954	6.6289	5.1213	5.3474
SW579	CTRP2	5.3959	6.437	5.2009	5.0362
HTC-C3	GDSC1; GDSC2	5.4263	7.2937	2.6978	0.6886
ASH-3	GDSC1; GDSC2	5.4349	6.7779	2.8887	0.1681
FTC-238	CTRP2	5.5555	6.1478	5.4794	3.5285
TT2609-C02	GDSC1; GDSC2; CTRP2	5.6153	7.7644	4.805	6.1018
BHT-101	GDSC1; GDSC2; CTRP2	5.6223	7.4398	4.9698	5.4036
8305C	GDSC1; GDSC2; CTRP2	5.6238	6.166	5.5472	3.0771
CGTH-W-1	GDSC1; CTRP2	5.6702	6.3301	5.5337	2.9988
8505C	GDSC1; GDSC2; CTRP2	5.6723	7.4703	5.0017	5.1583
B-CPAP	GDSC1; GDSC2; CTRP2	5.7409	6.6755	5.4503	3.1521
K5	GDSC1; GDSC2	5.7984	7.3451	2.8236	0.2065
ML-1 [Human leukemia]	GDSC1; GDSC2; CTRP2	5.8421	7.4934	5.1451	4.1896
FTC-133	GDSC1; GDSC2; CTRP2	6.3687	7.8711	5.3852	2.2044

Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
DOK	GDSC1; GDSC2	3.4867	5.6872	2.2736	6.1732
BB49-HNC	GDSC1; GDSC2	3.6326	5.5508	2.4546	4.6517
JHU-011	GDSC1; GDSC2	3.6747	5.4678	2.5269	4.0963
YD-10B	CTRP2	3.8107	9.0822	2.4161	20.1149
UPCI-SCC-090	GDSC1; GDSC2	4.0455	7.3741	1.8626	7.3235
OSC-19	GDSC1; GDSC2	4.1823	7.0346	2.1245	5.4118
PCI-38	GDSC1	4.3095	6.2279	1.7372	1.148
OSC-20	GDSC1; GDSC2	4.5013	6.422	2.6094	1.7865
JHU-029	GDSC2	4.5448	11.8245	0.0418	16.356
PCI-15A	GDSC1; GDSC2	4.5923	6.4384	2.6517	1.6797
SCC-25	GDSC1; GDSC2; CTRP2	4.7722	6.6791	4.4427	9.6767
KOSC-2	GDSC2	4.7824	11.3611	0.4449	13.7293
PCI-04B	GDSC1; GDSC2	4.8005	6.9321	2.5492	1.9184
HSC-3	GDSC1; GDSC2; CTRP2	4.8282	6.496	4.5712	9.0307
HO-1-N-1	GDSC1; GDSC2	4.8769	6.7782	2.6532	1.3321
HSC-4	GDSC1; GDSC2; CTRP2	4.9871	7.5725	4.2862	9.7212
KON	GDSC1; GDSC2	5.0152	7.0579	2.6052	1.3992
JHU-022	GDSC1; GDSC2	5.0311	13.4164	-0.3814	17.1653
Detroit 562	GDSC1; GDSC2; CTRP2	5.0337	6.8469	4.6523	8.1494
HO-1-u-1	GDSC1	5.044	6.5226	1.9166	0.1246
SCC-15	GDSC1; GDSC2	5.0686	8.4347	2.0328	3.7632
LB771-HNC	GDSC1; GDSC2	5.0969	8.55	1.9971	4.4081
PCI-30	GDSC1	5.1188	6.8086	1.8455	0.2105
BICR 78	GDSC1; GDSC2	5.2013	7.2634	2.6101	1.1925
SNU-1214	CTRP2	5.3377	7.3668	4.7303	7.0583
BICR 31	GDSC1; GDSC2; CTRP2	5.3415	7.2363	4.7947	6.7884
SNU-899	CTRP2	5.3886	6.1714	5.2904	4.7187
SKN-3	GDSC1; GDSC2	5.4244	7.993	2.4187	1.7968
BICR 22	GDSC1; GDSC2; CTRP2	5.4395	6.1052	5.3667	4.2871
PE/CA-PJ34 (clone C12)	CTRP2	5.4406	8.7111	4.1796	9.0869
YD-8	CTRP2	5.5034	7.3382	4.9055	5.9451
CAL-27	GDSC1; GDSC2; CTRP2	5.5378	12.4441	2.4131	16.0637
BHY	GDSC1; GDSC2; CTRP2	5.5644	6.8646	5.1881	4.6473
BICR 6	CTRP2	5.61	6.0972	5.5549	3.0887
SCC-4	GDSC1; GDSC2; CTRP2	5.6103	6.4607	5.4161	3.6193
PE/CA-PJ49	CTRP2	5.6136	6.2131	5.5194	3.2108
SCC-9	GDSC1; GDSC2; CTRP2	5.6269	13.2036	2.1111	17.0255
BICR 18	CTRP2	5.6549	6.6406	5.3815	3.6422
PE/CA-PJ15	GDSC1; GDSC2; CTRP2	5.6909	6.4269	5.5139	3.0214
BICR 10	GDSC1; GDSC2	5.6976	7.4208	2.7596	0.3717
SAS	GDSC1; GDSC2	5.7058	14.6481	-0.4985	16.1558
SNU-1076	CTRP2	5.7181	7.2544	5.1498	4.4413
HSC-2	GDSC1; GDSC2; CTRP2	5.7193	6.4559	5.5302	2.8835
SNU-1041	CTRP2	5.8017	10.3725	3.6749	10.4269
PE/CA-PJ41 (clone D2)	CTRP2	5.8734	6.7727	5.5295	2.5183
FaDu	GDSC1; GDSC2; CTRP2	5.8751	6.9857	5.4261	2.9453
CAL-33	GDSC1; GDSC2; CTRP2	5.9117	7.6719	5.1176	4.1595
SAT [Human HNSCC]	GDSC1; GDSC2	5.9621	9.0854	2.2298	2.067
PCI-06A	GDSC1; GDSC2	5.9728	8.2809	2.5525	0.8129
BICR 16	CTRP2	6.0847	7.3601	5.4198	2.5485
Ca9-22	GDSC1; GDSC2	6.1128	8.6953	2.4538	1.0492
BB30-HNC	GDSC1; GDSC2	6.1538	7.9909	2.7284	0.279
BICR 56	CTRP2	6.2105	7.4136	5.4928	2.017
SNU-46	CTRP2	6.2367	12.2917	3.0795	12.0227
NCI-H3118	GDSC1; GDSC2	6.2458	9.2553	2.2938	1.3562
SNU-1066	CTRP2	6.4121	9.1149	4.8038	4.5465

Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SW780	GDSC1; GDSC2	3.731	5.9313	2.3405	5.1208
UM-UC-1	CTRP2	4.9051	7.6994	4.1459	10.4908
RT-112	GDSC1; GDSC2; CTRP2	4.9915	6.7553	4.6455	8.2904
UM-UC-3	GDSC1; CTRP2	5.0318	7.9553	4.154	10.1437
BFTC-905	GDSC1; GDSC2	5.0474	6.4651	2.8528	0.4318
5637	GDSC1; GDSC2; CTRP2	5.1289	7.0888	4.6469	7.9193
RT-4	GDSC1; GDSC2; CTRP2	5.2495	6.7945	4.8992	6.6062
TCCSUP	GDSC1; GDSC2; CTRP2	5.2981	7.5377	4.6113	7.6381
JMSU-1	CTRP2	5.3912	7.0916	4.9109	6.1959
CAL-29	GDSC1; GDSC2; CTRP2	5.4694	6.5897	5.2148	4.7838
KU-19-19	GDSC1; GDSC2; CTRP2	5.5422	6.1477	5.465	3.6208
647V	GDSC1; GDSC2; CTRP2	5.5694	6.0717	5.5183	3.3443
SCaBER	CTRP2	5.6026	15.0891	1.1488	20.4783
BC-3C	CTRP2	5.605	6.3717	5.4481	3.5085
SW1710	GDSC1; GDSC2; CTRP2	5.6474	7.5719	4.929	5.5155
T24	GDSC1; GDSC2; CTRP2	5.6477	6.6599	5.3655	3.7245
VM-CUB-1	CTRP2	5.6824	6.9697	5.2538	4.095
KMBC-2	CTRP2	5.6879	6.2988	5.5652	2.8284
639V	GDSC1; GDSC2; CTRP2	5.6988	6.6082	5.4402	3.2961
HT-1197	GDSC1; GDSC2; CTRP2	5.827	7.2071	2.8808	0.0939
U-BLC1	CTRP2	5.8643	6.6726	5.57	2.3712
J82	GDSC1; GDSC2; CTRP2	5.9287	6.7252	5.6034	2.0897
HT-1376	GDSC1; GDSC2; CTRP2	5.9555	6.9574	5.5118	2.4164

Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
BPH-1	GDSC1; GDSC2	3.5883	5.4004	2.4955	4.5074
DSH1	GDSC1; GDSC2	3.6788	5.7524	2.3897	4.9423
JAR	GDSC1; GDSC2	3.7833	5.7822	2.4519	4.3031
ACC-OV7	GDSC1; GDSC2	3.9459	6.1285	2.3985	4.262
DoTc2 4510	GDSC1; GDSC2	3.9854	6.7818	2.1089	5.9494
PA-1	GDSC1; GDSC2	4.1012	6.0185	2.5546	3.0048
C-4-I	GDSC1; GDSC2	4.165	6.2892	2.4683	3.3888
OVCA433	GDSC1; GDSC2	4.2841	6.4218	2.4816	3.0872
LB831-BLC	GDSC1; GDSC2	4.4225	6.3466	2.5985	2.2005
NT2-D1	GDSC1	4.438	6.3061	1.7629	0.9146
NCC-IT	GDSC1	4.523	6.1111	1.8699	0.4601
HT-3	GDSC1; GDSC2	4.5406	8.6349	1.5997	7.7827
SKG-IIIa	GDSC1; GDSC2	4.5425	8.7591	1.5411	8.1254
MS751	GDSC1; GDSC2	4.7162	7.115	2.4227	2.6945
JEG-3	GDSC1; GDSC2	4.7481	6.769	2.5917	1.7755
OVCA420	GDSC1	4.7792	6.427	1.8544	0.3795
TC-YIK	GDSC2	4.8323	16.6726	-2.1402	24.3589
CAL-39	GDSC1; GDSC2	4.9616	7.2149	2.5123	1.8946
OMC-1 [Human cervical carcinoma]	GDSC1; GDSC2	4.9782	6.952	2.6309	1.3241
ME-180	GDSC1; GDSC2	4.9811	13.4545	-0.4369	17.5336
SiHa	GDSC1; GDSC2	5.1322	6.4226	2.9015	0.2642
HEY	GDSC1; GDSC2	5.1524	7.5726	2.4586	1.9206
NEC8	GDSC1; GDSC2	5.2037	6.6894	2.8327	0.4072
PEO1	GDSC1; GDSC2	5.2711	7.4518	2.5667	1.3075
SW954	GDSC1; GDSC2	5.2936	7.0052	2.7516	0.5986
KGN	GDSC1	5.4624	7.8298	1.6121	0.7554
PWR-1E	GDSC2	5.4964	7.723	2.5619	1.1249
SW756	GDSC1; GDSC2	5.6215	7.1067	2.8422	0.2222
HEC-1	GDSC1; GDSC2	5.7101	7.1436	2.8614	0.1663
SW962	GDSC1; GDSC2	5.7511	7.5305	2.7406	0.3951
HeLa	GDSC1; GDSC2; CTRP2	5.8564	6.3153	5.7321	1.7272
SiSo	GDSC1; GDSC2	5.9851	8.091	2.6283	0.5796
UWB1.289	GDSC1; GDSC2	5.993	8.0707	2.6388	0.5469
SKN	GDSC1; GDSC2	6.0433	8.2429	2.5955	0.5667
OVMIU	GDSC1; GDSC2	6.1643	8.4973	2.55	0.7087
C-33 A	GDSC1; GDSC2	6.294	8.1101	2.7377	0.2245
OV17R	GDSC1; GDSC2	6.3515	8.3877	2.6621	0.3472
JHOS-3	GDSC1; GDSC2	6.5868	8.5613	2.6872	0.2353
Ca Ski	GDSC1; GDSC2	6.6983	9.0033	2.574	0.4129

Drug-Drug Interaction (DDI) Information of This Drug

Coadministration of a Drug Treating the Same Disease as Ruxolitinib

DDI Drug Name	DDI Drug ID	Severity	Mechanism	Disease	REF
Fedratinib	DM4ZBK6	Minor	Decreased metabolism of Ruxolitinib caused by Fedratinib mediated inhibition of CYP450 enzyme.	Myeloproliferative neoplasm [2A20]	[11]

Coadministration of a Drug Treating the Disease Different from Ruxolitinib (Comorbidity)

DDI Drug Name	DDI Drug ID	Severity	Mechanism	Comorbidity	REF
Ivosidenib	DM8S6T7	Moderate	Increased metabolism of Ruxolitinib caused by Ivosidenib mediated induction of CYP450 enzyme.	Acute myeloid leukaemia [2A60]	[12]
Arn-509	DMT81LZ	Moderate	Increased metabolism of Ruxolitinib caused by Arn-509 mediated induction of CYP450 enzyme.	Acute myeloid leukaemia [2A60]	[12]
Pexidartinib	DMS2J0Z	Moderate	Increased metabolism of Ruxolitinib caused by Pexidartinib mediated induction of CYP450 enzyme.	Bone/articular cartilage neoplasm [2F7B]	[12]
Tucatinib	DMBESUA	Major	Decreased metabolism of Ruxolitinib caused by Tucatinib mediated inhibition of CYP450 enzyme.	Breast cancer [2C60-2C6Y]	[12]
Palbociclib	DMD7L94	Minor	Decreased metabolism of Ruxolitinib caused by Palbociclib mediated inhibition of CYP450 enzyme.	Breast cancer [2C60-2C6Y]	[11]
Levomilnacipran	DMV26S8	Moderate	Increased risk of bleeding by the combination of Ruxolitinib and Levomilnacipran.	Chronic pain [MG30]	[13]
Regorafenib	DMHSY1I	Major	Increased risk of bleeding by the combination of Ruxolitinib and Regorafenib.	Colorectal cancer [2B91]	[11]
Lumacaftor	DMCLWDJ	Moderate	Increased metabolism of Ruxolitinib caused by Lumacaftor mediated induction of CYP450 enzyme.	Cystic fibrosis [CA25]	[12]
MK-8228	DMOB58Q	Minor	Decreased metabolism of Ruxolitinib caused by MK-8228 mediated inhibition of CYP450 enzyme.	Cytomegaloviral disease [1D82]	[11]
Vortioxetine	DM6F1PU	Moderate	Increased risk of bleeding by the combination of Ruxolitinib and Vortioxetine.	Depression [6A70-6A7Z]	[13]
Apigenin	DMI3491	Minor	Increased risk of bleeding by the combination of Ruxolitinib and Apigenin.	Discovery agent [N.A.]	[14]
Stiripentol	DMMSDOY	Minor	Decreased metabolism of Ruxolitinib caused by Stiripentol mediated inhibition of CYP450 enzyme.	Epilepsy/seizure [8A61-8A6Z]	[11]
Tazemetostat	DMWP1BH	Moderate	Increased metabolism of Ruxolitinib caused by Tazemetostat mediated induction of CYP450 enzyme.	Follicular lymphoma [2A80]	[12]
Avapritinib	DMK2GZX	Major	Increased risk of bleeding by the combination of Ruxolitinib and Avapritinib.	Gastrointestinal stromal tumour [2B5B]	[11]
Cobicistat	DM6L4H2	Major	Decreased metabolism of Ruxolitinib caused by Cobicistat mediated inhibition of CYP450 enzyme.	Human immunodeficiency virus disease [1C60-1C62]	[12]
Teriflunomide	DMQ2FKJ	Major	Additive immunosuppressive effects by the combination of Ruxolitinib and Teriflunomide.	Hyper-lipoproteinaemia [5C80]	[15]
Berotralstat	DMWA2DZ	Minor	Decreased metabolism of Ruxolitinib caused by Berotralstat mediated inhibition of CYP450 enzyme.	Innate/adaptive immunodeficiency [4A00]	[11]
Suvorexant	DM0E6S3	Minor	Decreased metabolism of Ruxolitinib caused by Suvorexant mediated inhibition of CYP450 enzyme.	Insomnia [7A00-7A0Z]	[11]
Ceritinib	DMB920Z	Major	Decreased metabolism of Ruxolitinib caused by Ceritinib mediated inhibition of CYP450 enzyme.	Lung cancer [2C25]	[12]
PF-06463922	DMKM7EW	Moderate	Increased metabolism of Ruxolitinib caused by PF-06463922 mediated induction of CYP450 enzyme.	Lung cancer [2C25]	[12]
Selpercatinib	DMZR15V	Minor	Decreased metabolism of Ruxolitinib caused by Selpercatinib mediated inhibition of CYP450 enzyme.	Lung cancer [2C25]	[11]
Idelalisib	DM602WT	Major	Decreased metabolism of Ruxolitinib caused by Idelalisib mediated inhibition of CYP450 enzyme.	Mature B-cell leukaemia [2A82]	[12]
IPI-145	DMWA24P	Minor	Decreased metabolism of Ruxolitinib caused by IPI-145 mediated inhibition of CYP450 enzyme.	Mature B-cell leukaemia [2A82]	[11]
Acalabrutinib	DM7GCVW	Major	Increased risk of bleeding by the combination of Ruxolitinib and Acalabrutinib.	Mature B-cell lymphoma [2A85]	[16]
Ibrutinib	DMHZCPO	Major	Increased risk of bleeding by the combination of Ruxolitinib and Ibrutinib.	Mature B-cell lymphoma [2A85]	[17]
Ponatinib	DMYGJQO	Major	Increased risk of bleeding by the combination of Ruxolitinib and Ponatinib.	Mature B-cell lymphoma [2A85]	[18]
Vemurafenib	DM62UG5	Moderate	Increased metabolism of Ruxolitinib caused by Vemurafenib mediated induction of CYP450 enzyme.	Melanoma [2C30]	[12]
Dabrafenib	DMX6OE3	Moderate	Increased metabolism of Ruxolitinib caused by Dabrafenib mediated induction of CYP450 enzyme.	Melanoma [2C30]	[12]
Tecfidera	DM2OVDT	Moderate	Additive immunosuppressive effects by the combination of Ruxolitinib and Tecfidera.	Multiple sclerosis [8A40]	[19]
Siponimod	DM2R86O	Major	Additive immunosuppressive effects by the combination of Ruxolitinib and Siponimod.	Multiple sclerosis [8A40]	[20]
Ocrelizumab	DMEZ2KH	Moderate	Additive immunosuppressive effects by the combination of Ruxolitinib and Ocrelizumab.	Multiple sclerosis [8A40]	[21]
Ozanimod	DMT6AM2	Major	Additive immunosuppressive effects by the combination of Ruxolitinib and Ozanimod.	Multiple sclerosis [8A40]	[11]
Netupitant	DMEKAYI	Minor	Decreased metabolism of Ruxolitinib caused by Netupitant mediated inhibition of CYP450 enzyme.	Nausea/vomiting [MD90]	[11]
Entrectinib	DMMPTLH	Minor	Decreased metabolism of Ruxolitinib caused by Entrectinib mediated inhibition of CYP450 enzyme.	Non-small cell lung cancer [2C25]	[11]
Rucaparib	DM9PVX8	Minor	Decreased metabolism of Ruxolitinib caused by Rucaparib mediated inhibition of CYP450 enzyme.	Ovarian cancer [2C73]	[11]
Abametapir	DM2RX0I	Moderate	Decreased metabolism of Ruxolitinib caused by Abametapir mediated inhibition of CYP450 enzyme.	Pediculosis [1G00]	[22]
Lefamulin	DME6G97	Moderate	Decreased metabolism of Ruxolitinib caused by Lefamulin mediated inhibition of CYP450 enzyme.	Pneumonia [CA40]	[11]
Enzalutamide	DMGL19D	Moderate	Increased metabolism of Ruxolitinib caused by Enzalutamide mediated induction of CYP450 enzyme.	Prostate cancer [2C82]	[12]
Anthrax vaccine	DM9GSWY	Moderate	Antagonize the effect of Ruxolitinib when combined with Anthrax vaccine.	Sepsis [1G40-1G41]	[23]
Voxelotor	DMCS6M5	Minor	Decreased metabolism of Ruxolitinib caused by Voxelotor mediated inhibition of CYP450 enzyme.	Sickle-cell disorder [3A51]	[11]
Telotristat ethyl	DMDIYFZ	Moderate	Increased metabolism of Ruxolitinib caused by Telotristat ethyl mediated induction of CYP450 enzyme.	Small intestine developmental anomaly [DA90]	[11]
Larotrectinib	DM26CQR	Minor	Decreased metabolism of Ruxolitinib caused by Larotrectinib mediated inhibition of CYP450 enzyme.	Solid tumour/cancer [2A00-2F9Z]	[11]
LEE011	DMMX75K	Minor	Decreased metabolism of Ruxolitinib caused by LEE011 mediated inhibition of CYP450 enzyme.	Solid tumour/cancer [2A00-2F9Z]	[11]
Fostamatinib	DM6AUHV	Moderate	Decreased metabolism of Ruxolitinib caused by Fostamatinib mediated inhibition of CYP450 enzyme.	Thrombocytopenia [3B64]	[24]
Elagolix	DMB2C0E	Moderate	Increased metabolism of Ruxolitinib caused by Elagolix mediated induction of CYP450 enzyme.	Uterine fibroid [2E86]	[12]
Betrixaban	DM2C4RF	Major	Increased risk of bleeding by the combination of Ruxolitinib and Betrixaban.	Venous thromboembolism [BD72]	[25]

Drug Inactive Ingredient(s) (DIG) and Formulation(s) of This Drug

DIG

DIG Name	DIG ID	PubChem CID	Functional Classification
Hydroxypropyl cellulose	E00632	Not Available	Binding agent; Coating agent; Emulsifying agent; Film/Membrane-forming agent; Modified-release agent; Suspending agent; Viscosity-controlling agent
Lactose monohydrate	E00393	104938	Binding agent; Diluent; Dry powder inhaler carrier; Lyophilization aid
Magnesium stearate	E00208	11177	lubricant
Povidone	E00667	Not Available	Binding agent; Coating agent; Disintegrant; Film/membrane-forming agent; Solubilizing agent; Suspending agent
Silicon dioxide	E00670	Not Available	Anticaking agent; Opacifying agent; Viscosity-controlling agent
Hydrophobic colloidal silica	E00285	24261	Anticaking agent; Emulsion stabilizing agent; Glidant; Suspending agent; Viscosity-controlling agent
Cellulose microcrystalline	E00698	Not Available	Adsorbent; Suspending agent; Diluent

Pharmaceutical Formulation

Formulation Name	Drug Dosage	Dosage Form	Route
Ruxolitinib Phosphate eq 5mg base tablet	eq 5mg base	Tablet	Oral
Ruxolitinib Phosphate eq 10mg base tablet	eq 10mg base	Tablet	Oral
Ruxolitinib Phosphate eq 15mg base tablet	eq 15mg base	Tablet	Oral
Ruxolitinib Phosphate eq 20mg base tablet	eq 20mg base	Tablet	Oral
Ruxolitinib Phosphate eq 25mg base tablet	eq 25mg base	Tablet	Oral
Ruxolitinib 10 mg tablet	10 mg	Oral Tablet	Oral
Ruxolitinib 15 mg tablet	15 mg	Oral Tablet	Oral
Ruxolitinib 20 mg tablet	20 mg	Oral Tablet	Oral
Ruxolitinib 25 mg tablet	25 mg	Oral Tablet	Oral
Ruxolitinib 5 mg tablet	5 mg	Oral Tablet	Oral

Jump to Detail Pharmaceutical Formulation Page of This Drug

References

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