Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DEJVYAZ)

• DME Name: Cytochrome P450 2A6 (CYP2A6) DME Info
• Gene Name: CYP2A6

Molecule-Related Drug & Molecule List

48 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[1]
Apremilast	DMTWS9E	Psoriasis vulgaris	EA90	Approved	[2]
Arformoterol	DMYM974	Chronic obstructive pulmonary disease	CA22	Approved	[3]
Artemisinin	DMOY7W3	Malaria	1F40-1F45	Approved	[4]
Artesunate	DMR27C8	Infection of P. falciparum	1F40	Approved	[5]
Azelastine	DMXTMBJ	Allergic conjunctivitis	9A60.02	Approved	[6]
Camphor	DMWIO46	Acute or chronic pain	MG30-MG31	Approved	[7]
Cenobamate	DM8KLU9	Complex partial seizure	8A68.0	Approved	[8]
Chlorzoxazone	DMCYVDT	Acute pain	MG31	Approved	[9]
Cinnarizine	DM7U5QJ	Meniere disease	AB31.0	Approved	[10]
Cisapride	DMY7PED	Gastroesophageal reflux disease	DA22.Z	Approved	[11]
Clofibrate	DMPC1J7	Dysbetalipoproteinemia	5C80.2	Approved	[12]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[13]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[14]
Dapagliflozin	DM28UJG	Non-insulin dependent diabetes	5A11	Approved	[15]
Dexmedetomidine	DM93L4X	Irritability	MB24	Approved	[16]
Flunarizine	DMZU5JP	Migraine	8A80	Approved	[12]
Flunitrazepam	DMGR5Z3	Insomnia	7A00-7A0Z	Approved	[17]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[18]
Flurazepam	DMAL4G0	Insomnia	7A00-7A0Z	Approved	[19]
Halothane	DM80OZ5	Anaesthesia	9A78.6	Approved	[20]
Ifosfamide	DMCT3I8	Adult central nervous system germ cell tumor		Approved	[21]
Letrozole	DMH07Y3	Estrogen-receptor positive breast cancer		Approved	[22]
Lidocaine	DML4ZOT	Anaesthesia	9A78.6	Approved	[23]
Lorcaserin	DMG6OYJ	Obesity	5B81	Approved	[24]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[25]
Methoxsalen	DME8FZ9	Cutaneous T-cell lymphoma	2B01	Approved	[4]
Methoxyflurane	DML0RAE	Anaesthesia	9A78.6	Approved	[26]
Metronidazole	DMTIVEN	Abscess		Approved	[27]
Montelukast	DMD157S	Allergic asthma	CA23.0	Approved	[10]
Nevirapine	DM6HX9B	Human immunodeficiency virus infection	1C62	Approved	[10]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[28]
Norethindrone acetate	DMDGCQP	N. A.	N. A.	Approved	[29]
Perazine	DM2AOTZ	Psychotic disorder	6A20-6A25	Approved	[30]
Pilocarpine	DMV9ADG	Glaucoma/ocular hypertension	9C61	Approved	[31]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[23]
Propofol	DMB4OLE	Anaesthesia	9A78.6	Approved	[32]
Selegiline Hydrochloride	DM3VR1L	Parkinson disease	8A00.0	Approved	[33]
Sevoflurane	DMC9O43	Anaesthesia	9A78.6	Approved	[26]
Tamoxifen	DMLB0EZ	Breast cancer	2C60-2C65	Approved	[34]
Tegafur	DM31ZQM	Solid tumour/cancer	2A00-2F9Z	Approved	[35]
Thalidomide	DM70BU5	Adult T-cell leukemia/lymphoma		Approved	[36]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[23]
UFT	DMX3O0D	Solid tumour/cancer	2A00-2F9Z	Approved	[37]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[38]
Vortioxetine	DM6F1PU	Major depressive disorder	6A70.3	Approved	[39]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[23]
Medifoxamine	DM0UGYX	N. A.	N. A.	Phase 4	[23]

5 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
5-methoxypsoralen	DME2A8X	Psoriasis vulgaris	EA90	Phase 3	[40]
Clomethiazole	DMSPN58	Stroke	8B20	Phase 3	[23]
Plitidepsin	DMJ8AUE	Multiple myeloma	2A83	Phase 3	[41]
BMS 650032	DMQI43G	Hepatitis C virus infection	1E51.1	Phase 2	[42]
Roxatidine	DMIZMYQ	N. A.	N. A.	Phase 2	[43]

1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Phenacetin	DMRQAM0	Analgesia	MB40.8	Withdrawn from market	[44]

7 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Chloroxylenol	DMM75WZ	N. A.	N. A.	Investigative	[23]
Fenthion	DMKEG49	N. A.	N. A.	Investigative	[45]
Fenthion sulfoxide	DM4OLRS	N. A.	N. A.	Investigative	[45]
flavone	DMEQH6J	Discovery agent	N.A.	Investigative	[46]
Levoverbenone	DMV3P89	N. A.	N. A.	Investigative	[47]
Nicotinyl alcohol	DMO7M2N	N. A.	N. A.	Investigative	[48]
Phenazone	DMCE985	Discovery agent	N.A.	Investigative	[49]

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