Details of Disease

General Information of Disease (ID: DIS2I5AB)

• Disease Name: Tinea corporis
• Synonyms: dermatophytosis of the trunk; dermatophytosis of the body
• Disease Class: 1F28: Dermatophytosis
• Definition: A dermatophyte disease of the glabrous skin, excluding the scalp, beard, face, hands, feet, and groin.
• Disease Hierarchy:
  DISM7JPJ: Dermatophytosis
  DIS2I5AB: Tinea corporis
• ICD Code: ICD-11: ICD-11: 1F28.Y
• Disease Identifiers:
  MONDO ID: MONDO_0001461
  MESH ID: D014005
  UMLS CUI: C0040252
  MedGen ID: 508197
  SNOMED CT ID: 84849002

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 20 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Benzocaine	DMI18HW	Approved	Small molecular drug	[1]
Betamethasone	DMAHJEF	Approved	Small molecular drug	[2]
Butenafine	DMOJ4ZI	Approved	Small molecular drug	[3]
Ciclopirox	DMN5T2A	Approved	Small molecular drug	[4]
Clotrimazole	DMMFCIH	Approved	Small molecular drug	[5]
Cortisone Acetate	DMG8K57	Approved	Small molecular drug	[6]
Econazole	DMFSWGH	Approved	Small molecular drug	[7]
Griseofulvin	DMK54YG	Approved	Small molecular drug	[8]
Haloprogin	DMH4IVU	Approved	Small molecular drug	[9]
Hydrocortisone	DMGEMB7	Approved	Small molecular drug	[10]
Ketoconazole	DMPZI3Q	Approved	Small molecular drug	[11]
Luliconazole	DMT73J8	Approved	Small molecular drug	[12]
Miconazole	DMPMYE8	Approved	Small molecular drug	[13]
Naftifine	DMHVBG1	Approved	Small molecular drug	[14]
Oxiconazole	DME7KRM	Approved	Small molecular drug	[15]
Pramoxine	DMZ2LGD	Approved	Small molecular drug	[16]
Salicyclic acid	DM2F8XZ	Approved	Small molecular drug	[17]
Sulconazole	DM2SDUF	Approved	Small molecular drug	[18]
Terbinafine	DMI6HUW	Approved	Small molecular drug	[19]
Tolnaftate	DM28MU7	Approved	Small molecular drug	[20]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
SQLE	TTE14XG	Strong	Genetic Variation	[21]

References

• [1] Benzocaine: Review on a Drug with Unfold Potential. Mini Rev Med Chem. 2020;20(1):3-11.
• [2] Betamethasone FDA Label
• [3] Butenafine FDA Label
• [4] Ciclopirox FDA Label
• [5] Clotrimazole FDA Label
• [6] Cortisone acetate FDA Label
• [7] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [8] Griseofulvin FDA Label
• [9] Haloprogin FDA Label
• [10] Hydrocortisone FDA Label
• [11] Ketoconazole FDA Label
• [12] Luliconazole FDA Label
• [13] Miconazole FDA Label
• [14] Naftifine FDA Label
• [15] Oxiconazole FDA Label
• [16] Pramoxine FDA Label
• [17] A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
• [18] Sulconazole FDA Label
• [19] Terbinafine FDA Label
• [20] Butenafine. Drugs. 1998 Mar;55(3):405-12; discussion 413.
• [21] A new mutation in the SQLE gene of Trichophyton mentagrophytes associated to terbinafine resistance in a couple with disseminated tinea corporis.J Mycol Med. 2019 Dec;29(4):352-355. doi: 10.1016/j.mycmed.2019.100903. Epub 2019 Sep 24.