Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMIWLJE)

Drug Name	Guanine Drug Info
Cross-matching ID	PubChem CID 135398634 ChEBI ID CHEBI:16235 CAS Number CAS 73-40-5 TTD Drug ID DMIWLJE

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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Drug(s) Targeting GTP cyclohydrolase-I (GCH1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ProSavin	DMJ42E6	Parkinson disease	8A00.0	Phase 1/2	[2]
OXB-102	DMXF9DM	Parkinson disease	8A00.0	Phase 1/2	[3]
2-Propanol, Isopropanol	DML5O0H	Discovery agent	N.A.	Investigative	[4]
Guanosine-5'-Triphosphate	DMV2OJX	Discovery agent	N.A.	Investigative	[5]
8-hydroxyguanine	DMT9BPN	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	GTP cyclohydrolase I feedback regulatory protein-dependent and -independent inhibitors of GTP cyclohydrolase I. Arch Biochem Biophys. 2001 Apr 1;388(1):67-73.
2	Clinical pipeline report, company report or official report of Oxford BioMedica.
3	Clinical pipeline report, company report or official report of Oxford BioMedica.
4	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
5	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.