Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMO7920)

• Drug Name: AM-831 Drug Info
• Synonyms: 199330-66-0; METHYL 4-AMINOTETRAHYDRO-2H-PYRAN-4-CARBOXYLATE HYDROCHLORIDE; methyl 4-aminooxane-4-carboxylate hydrochloride; METHYL 4-AMINOTETRAHYDROPYRAN-4-CARBOXYLATE HCL; methyl 4-aminotetrahydropyran-4-carboxylate hydrochloride; 2H-Pyran-4-carboxylic acid, 4-aminotetrahydro-, methyl ester, hydrochloride (1:1); SCHEMBL1818830; MolPort-009-013-807; VNPBPEQYIQVYDP-UHFFFAOYSA-N; AM831; KS-000008CU; SBB091929; AKOS025147281; PB10899; AS-36521; DB-065487; CS-0049053; FT-0768000; Q-1506; methyl 4-aminooxane-4-carboxylate,hydroch

Indication

Disease Entry	ICD 11	Status	REF
Schizophrenia	6A20	Discontinued in Phase 1	[1]

• Cross-matching ID:
  PubChem CID: 43811077
  TTD Drug ID: DMO7920

Molecule-Related Drug Atlas

Drug(s) Targeting 5-HT 2A receptor (HTR2A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Metergolin	DMJFP6G	Hyperprolactinaemia	5A60.1	Approved	[3]
ZOTEPINE	DMF3VXA	Anxiety disorder	6B00-6B0Z	Approved	[4]
Iloperidone	DM6AUFY	Schizophrenia	6A20	Approved	[5]
Flibanserin	DM70DTN	Depression	6A70-6A7Z	Approved	[6]
Lurasidone hydrochloride	DMCVPXO	Schizophrenia	6A20	Approved	[7]
Aniracetam	DMOIFW0	Cerebrovascular ischaemia	8B1Z	Approved	[8]
lumateperone tosylate	DMQ8HOJ	Schizophrenia	6A20	Approved	[9]
Sarpogrelate	DMGLP6S	Diabetic complication	5A2Y	Approved	[10]
Pimavanserin	DMR7IVC	Parkinson disease	8A00.0	Approved	[11]
Zicronapine	DMP8ESD	Schizophrenia	6A20	Phase 3	[12]

Drug(s) Targeting Dopamine D2 receptor (D2R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dopamine	DMPGUCF	Acromegaly	5A60.0	Approved	[13]
Haloperidol	DM96SE0	Delirium		Approved	[14]
Perphenazine	DMA4MRX	Schizophrenia	6A20	Approved	[15]
Perazine	DM2AOTZ	Psychotic disorder	6A20-6A25	Approved	[16]
Domperidone	DMBDPY0	Gastrointestinal disease	DE2Z	Approved	[17]
Levodopa	DMN3E57	Parkinson disease	8A00.0	Approved	[18]
Quetiapine	DM1N62C	Anorexia nervosa cachexia	6B80	Approved	[19]
Pimozide	DMW83TP	Schizophrenia	6A20	Approved	[20]
Chlorpromazine	DMBGZI3	Acute intermittent hepatic porphyria	5C58.11	Approved	[21]
Iloperidone	DM6AUFY	Schizophrenia	6A20	Approved	[5]

Drug(s) Targeting Muscarinic acetylcholine receptor M5 (CHRM5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Promazine	DMZAL7W	Acute intermittent hepatic porphyria	5C58.11	Approved	[22]
ACECLIDINE	DMOLNCZ	Glaucoma/ocular hypertension	9C61	Approved	[23]
Pilocarpine	DMV9ADG	Glaucoma/ocular hypertension	9C61	Approved	[24]
Anisodine	DMNOSWU	Central and peripheral nervous disease	8A04-8E7Z	Approved	[25]
Atropine	DMEN6X7	Organophosphate poisoning	NE6Z	Approved	[26]
Propiverine	DMUWBIJ	Urinary incontinence	MF50.2	Approved	[27]
Umeclidinium	DM4E8O9	Chronic obstructive pulmonary disease	CA22	Approved	[28]
Cimetropium bromide	DMZHPNE	Gastric motility disorder	DA21	Approved	[29]
Butylscopolamine	DMZKXB7	Dysmenorrhea	GA34.3	Approved	[30]
Trospium	DMX6RTG	Overactive bladder	GC50.0	Approved	[31]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
5-HT 2A receptor (HTR2A)	TTJQOD7	5HT2A_HUMAN	Agonist	[2]
Dopamine D2 receptor (D2R)	TTEX248	DRD2_HUMAN	Agonist	[2]
Muscarinic acetylcholine receptor M5 (CHRM5)	TTH18TF	ACM5_HUMAN	Agonist	[2]

References

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