DDI Drug Name |
DDI Drug ID |
Severity |
Mechanism |
Comorbidity |
REF |
Ivosidenib |
DM8S6T7
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Ivosidenib. |
Acute myeloid leukaemia [2A60]
|
[12] |
Midostaurin |
DMI6E0R
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Midostaurin. |
Acute myeloid leukaemia [2A60]
|
[13] |
Daunorubicin |
DMQUSBT
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Daunorubicin. |
Acute myeloid leukaemia [2A60]
|
[13] |
Arn-509 |
DMT81LZ
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Arn-509. |
Acute myeloid leukaemia [2A60]
|
[14] |
Gilteritinib |
DMTI0ZO
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Gilteritinib. |
Acute myeloid leukaemia [2A60]
|
[15] |
Oliceridine |
DM6MDCF
|
Major |
Additive CNS depression effects by the combination of Promazine and Oliceridine. |
Acute pain [MG31]
|
[16] |
Scopolamine |
DMOM8AL
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Scopolamine. |
Addictive disorder [6C50-6C5Z]
|
[17] |
Mepyramine |
DMB4SFH
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Mepyramine. |
Allergic/hypersensitivity disorder [4A80-4A8Z]
|
[18] |
Memantine |
DMD9WSC
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Memantine. |
Alzheimer disease [8A20]
|
[17] |
Galantamine |
DMEO794
|
Moderate |
Antagonize the effect of Promazine when combined with Galantamine. |
Alzheimer disease [8A20]
|
[19] |
Rivastigmine |
DMG629M
|
Moderate |
Antagonize the effect of Promazine when combined with Rivastigmine. |
Alzheimer disease [8A20]
|
[19] |
Donepezil |
DMIYG7Z
|
Moderate |
Antagonize the effect of Promazine when combined with Donepezil. |
Alzheimer disease [8A20]
|
[19] |
Metronidazole |
DMTIVEN
|
Minor |
Increased risk of prolong QT interval by the combination of Promazine and Metronidazole. |
Amoebiasis [1A36]
|
[20] |
Isosorbide dinitrate |
DMBI4JG
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Isosorbide dinitrate. |
Anal fissure/fistula [DB50]
|
[21] |
Ivabradine |
DM0L594
|
Major |
Increased risk of ventricular arrhythmias by the combination of Promazine and Ivabradine. |
Angina pectoris [BA40]
|
[14] |
Dronedarone |
DMA8FS5
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Dronedarone. |
Angina pectoris [BA40]
|
[13] |
Amyl nitrite |
DMJKO05
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Amyl nitrite. |
Angina pectoris [BA40]
|
[21] |
Nifedipine |
DMSVOZT
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Nifedipine. |
Angina pectoris [BA40]
|
[21] |
Bedaquiline |
DM3906J
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Bedaquiline. |
Antimicrobial drug resistance [MG50-MG52]
|
[22] |
Hydroxyzine |
DMF8Y74
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Hydroxyzine. |
Anxiety disorder [6B00-6B0Z]
|
[17] |
Cilostazol |
DMZMSCT
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Cilostazol. |
Arterial occlusive disease [BD40]
|
[13] |
Posaconazole |
DMUL5EW
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Posaconazole. |
Aspergillosis [1F20]
|
[13] |
Levalbuterol |
DM5YBO1
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Levalbuterol. |
Asthma [CA23]
|
[23] |
Terbutaline |
DMD4381
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Terbutaline. |
Asthma [CA23]
|
[24] |
Pirbuterol |
DMI5678
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Pirbuterol. |
Asthma [CA23]
|
[23] |
Salbutamol |
DMN9CWF
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Salbutamol. |
Asthma [CA23]
|
[23] |
Formoterol |
DMSOURV
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Formoterol. |
Asthma [CA23]
|
[24] |
Lisdexamfetamine |
DM6W8V5
|
Moderate |
Antagonize the effect of Promazine when combined with Lisdexamfetamine. |
Attention deficit hyperactivity disorder [6A05]
|
[25] |
Methylphenidate |
DM7SJD6
|
Moderate |
Antagonize the effect of Promazine when combined with Methylphenidate. |
Attention deficit hyperactivity disorder [6A05]
|
[25] |
Ofloxacin |
DM0VQN3
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Ofloxacin. |
Bacterial infection [1A00-1C4Z]
|
[26] |
Ciprofloxacin XR |
DM2NLS9
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Ciprofloxacin XR. |
Bacterial infection [1A00-1C4Z]
|
[13] |
Clarithromycin |
DM4M1SG
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Clarithromycin. |
Bacterial infection [1A00-1C4Z]
|
[13] |
Sulfamethoxazole |
DMB08GE
|
Minor |
Increased risk of prolong QT interval by the combination of Promazine and Sulfamethoxazole. |
Bacterial infection [1A00-1C4Z]
|
[13] |
Linezolid |
DMGFPU2
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Linezolid. |
Bacterial infection [1A00-1C4Z]
|
[27] |
Gemifloxacin |
DMHT34O
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Gemifloxacin. |
Bacterial infection [1A00-1C4Z]
|
[26] |
Norfloxacin |
DMIZ6W2
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Norfloxacin. |
Bacterial infection [1A00-1C4Z]
|
[20] |
Telithromycin |
DMZ4P3A
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Telithromycin. |
Bacterial infection [1A00-1C4Z]
|
[13] |
Retigabine |
DMGNYIH
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Retigabine. |
Behcet disease [4A62]
|
[28] |
Cariprazine |
DMJYDVK
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Cariprazine. |
Bipolar disorder [6A60]
|
[17] |
Loperamide |
DMOJZQ9
|
Moderate |
Additive antimotility effects by the combination of Promazine and Loperamide. |
Bowel habit change [ME05]
|
[29] |
Eribulin |
DM1DX4Q
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Eribulin. |
Breast cancer [2C60-2C6Y]
|
[13] |
Tamoxifen |
DMLB0EZ
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Tamoxifen. |
Breast cancer [2C60-2C6Y]
|
[13] |
Toremifene |
DMQYUWG
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Toremifene. |
Breast cancer [2C60-2C6Y]
|
[13] |
Sotalol |
DML60TN
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Sotalol. |
Cardiac arrhythmia [BC9Z]
|
[13] |
Acetylcholine |
DMDF79Z
|
Moderate |
Antagonize the effect of Promazine when combined with Acetylcholine. |
Cataract [9B10]
|
[30] |
PF-04449913 |
DMSB068
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and PF-04449913. |
Chronic myelomonocytic leukaemia [2A40]
|
[31] |
Umeclidinium |
DM4E8O9
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Umeclidinium. |
Chronic obstructive pulmonary disease [CA22]
|
[32] |
Olodaterol |
DM62B78
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Olodaterol. |
Chronic obstructive pulmonary disease [CA22]
|
[24] |
Vilanterol |
DMF5EK1
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Vilanterol. |
Chronic obstructive pulmonary disease [CA22]
|
[23] |
Tiotropium |
DMFDC0Q
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Tiotropium. |
Chronic obstructive pulmonary disease [CA22]
|
[32] |
Salmeterol |
DMIEU69
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Salmeterol. |
Chronic obstructive pulmonary disease [CA22]
|
[24] |
Revefenacin |
DMMP5SI
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Revefenacin. |
Chronic obstructive pulmonary disease [CA22]
|
[32] |
Indacaterol |
DMQJHR7
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Indacaterol. |
Chronic obstructive pulmonary disease [CA22]
|
[24] |
Dihydrocodeine |
DMB0FWL
|
Major |
Additive CNS depression effects by the combination of Promazine and Dihydrocodeine. |
Chronic pain [MG30]
|
[16] |
Oxaliplatin |
DMQNWRD
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Oxaliplatin. |
Colorectal cancer [2B91]
|
[13] |
Isoproterenol |
DMK7MEY
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Isoproterenol. |
Conduction disorder [BC63]
|
[23] |
Olopatadine |
DMKMWQG
|
Moderate |
Additive CNS depression effects by the combination of Promazine and Olopatadine. |
Conjunctiva disorder [9A60]
|
[33] |
Halothane |
DM80OZ5
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Halothane. |
Corneal disease [9A76-9A78]
|
[13] |
Propofol |
DMB4OLE
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Propofol. |
Corneal disease [9A76-9A78]
|
[34] |
Sevoflurane |
DMC9O43
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Sevoflurane. |
Corneal disease [9A76-9A78]
|
[13] |
Alfentanil |
DMVO0UB
|
Major |
Additive CNS depression effects by the combination of Promazine and Alfentanil. |
Corneal disease [9A76-9A78]
|
[35] |
Remifentanil |
DMZTXCH
|
Major |
Additive CNS depression effects by the combination of Promazine and Remifentanil. |
Corneal disease [9A76-9A78]
|
[35] |
Clofazimine |
DMEBOFW
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Clofazimine. |
Crohn disease [DD70]
|
[36] |
Mifepristone |
DMGZQEF
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Mifepristone. |
Cushing syndrome [5A70]
|
[13] |
Pasireotide |
DMHM7JS
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Pasireotide. |
Cushing syndrome [5A70]
|
[13] |
Sertraline |
DM0FB1J
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Sertraline. |
Depression [6A70-6A7Z]
|
[13] |
Trimipramine |
DM1SC8M
|
Moderate |
Increased plasma concentrations of Promazine and Trimipramine due to competitive inhibition of the same metabolic pathway. |
Depression [6A70-6A7Z]
|
[37] |
Imipramine |
DM2NUH3
|
Moderate |
Increased plasma concentrations of Promazine and Imipramine due to competitive inhibition of the same metabolic pathway. |
Depression [6A70-6A7Z]
|
[37] |
Fluoxetine |
DM3PD2C
|
Moderate |
Decreased metabolism of Promazine caused by Fluoxetine mediated inhibition of CYP450 enzyme. |
Depression [6A70-6A7Z]
|
[38] |
Nortriptyline |
DM4KDYJ
|
Moderate |
Increased plasma concentrations of Promazine and Nortriptyline due to competitive inhibition of the same metabolic pathway. |
Depression [6A70-6A7Z]
|
[37] |
Paroxetine |
DM5PVQE
|
Moderate |
Decreased metabolism of Promazine caused by Paroxetine mediated inhibition of CYP450 enzyme. |
Depression [6A70-6A7Z]
|
[39] |
Selegiline |
DM6034S
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Selegiline. |
Depression [6A70-6A7Z]
|
[27] |
Duloxetine |
DM9BI7M
|
Moderate |
Decreased metabolism of Promazine caused by Duloxetine mediated inhibition of CYP450 enzyme. |
Depression [6A70-6A7Z]
|
[40] |
Isocarboxazid |
DMAF1NB
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Isocarboxazid. |
Depression [6A70-6A7Z]
|
[27] |
Escitalopram |
DMFK9HG
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Escitalopram. |
Depression [6A70-6A7Z]
|
[13] |
OPC-34712 |
DMHG57U
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and OPC-34712. |
Depression [6A70-6A7Z]
|
[17] |
Phenelzine |
DMHIDUE
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Phenelzine. |
Depression [6A70-6A7Z]
|
[27] |
Clomipramine |
DMINRKW
|
Moderate |
Increased plasma concentrations of Promazine and Clomipramine due to competitive inhibition of the same metabolic pathway. |
Depression [6A70-6A7Z]
|
[37] |
Trazodone |
DMK1GBJ
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Trazodone. |
Depression [6A70-6A7Z]
|
[41] |
Amoxapine |
DMKITQE
|
Moderate |
Increased plasma concentrations of Promazine and Amoxapine due to competitive inhibition of the same metabolic pathway. |
Depression [6A70-6A7Z]
|
[37] |
Doxepin |
DMPI98T
|
Moderate |
Increased plasma concentrations of Promazine and Doxepin due to competitive inhibition of the same metabolic pathway. |
Depression [6A70-6A7Z]
|
[42] |
Maprotiline |
DMPWB7T
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Maprotiline. |
Depression [6A70-6A7Z]
|
[17] |
Esketamine |
DMVU687
|
Moderate |
Additive CNS depression effects by the combination of Promazine and Esketamine. |
Depression [6A70-6A7Z]
|
[20] |
Nitroglycerin |
DMQ2491
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Nitroglycerin. |
Diabetic foot ulcer [BD54]
|
[21] |
Hyoscyamine |
DM804UR
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Hyoscyamine. |
Digestive system disease [DE2Z]
|
[17] |
Mepenzolate |
DM8YU2F
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Mepenzolate. |
Digestive system disease [DE2Z]
|
[18] |
Oxybutynine |
DMJPBAX
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Oxybutynine. |
Discovery agent [N.A.]
|
[17] |
Tetrabenazine |
DMYWQ0O
|
Major |
Additive antidopaminergic effects by the combination of Promazine and Tetrabenazine. |
Dissociative neurological symptom disorder [6B60]
|
[43] |
Meclizine |
DMS7T13
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Meclizine. |
Dizziness and giddiness [MB48]
|
[17] |
Deutetrabenazine |
DMUPFLI
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Deutetrabenazine. |
Dystonic disorder [8A02]
|
[44] |
Ingrezza |
DMVPLNC
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Ingrezza. |
Dystonic disorder [8A02]
|
[45] |
Zonisamide |
DM0DTF7
|
Major |
Increased risk of hyperpyrexia by the combination of Promazine and Zonisamide. |
Epilepsy/seizure [8A61-8A6Z]
|
[46] |
Stiripentol |
DMMSDOY
|
Moderate |
Decreased metabolism of Promazine caused by Stiripentol mediated inhibition of CYP450 enzyme. |
Epilepsy/seizure [8A61-8A6Z]
|
[47] |
Guanabenz |
DM5QWEL
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Guanabenz. |
Essential hypertension [BA00]
|
[48] |
Ethacrynic acid |
DM60QMR
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Ethacrynic acid. |
Essential hypertension [BA00]
|
[48] |
Phenoxybenzamine |
DM8KSQH
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Phenoxybenzamine. |
Essential hypertension [BA00]
|
[21] |
Nicardipine |
DMCDYW7
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Nicardipine. |
Essential hypertension [BA00]
|
[21] |
Mecamylamine |
DMGQFYB
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Mecamylamine. |
Essential hypertension [BA00]
|
[21] |
Nadolol |
DMW6GVL
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Nadolol. |
Essential hypertension [BA00]
|
[21] |
Solifenacin |
DMG592Q
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Solifenacin. |
Functional bladder disorder [GC50]
|
[13] |
Tolterodine |
DMSHPW8
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Tolterodine. |
Functional bladder disorder [GC50]
|
[17] |
Darifenacin |
DMWXLYZ
|
Moderate |
Decreased metabolism of Promazine caused by Darifenacin mediated inhibition of CYP450 enzyme. |
Functional bladder disorder [GC50]
|
[49] |
Pentamidine |
DMHZJCG
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Pentamidine. |
Fungal infection [1F29-1F2F]
|
[13] |
Terbinafine |
DMI6HUW
|
Moderate |
Decreased metabolism of Promazine caused by Terbinafine mediated inhibition of CYP450 enzyme. |
Fungal infection [1F29-1F2F]
|
[50] |
Amphotericin B |
DMTAJQE
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Amphotericin B. |
Fungal infection [1F29-1F2F]
|
[20] |
Phentolamine |
DMXYJOB
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Phentolamine. |
Gangrene [MC85]
|
[21] |
Propantheline |
DM2EN6G
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Propantheline. |
Gastric ulcer [DA60]
|
[17] |
Sunitinib |
DMCBJSR
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Sunitinib. |
Gastrointestinal stromal tumour [2B5B]
|
[13] |
Acetazolamide |
DM1AF5U
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Acetazolamide. |
Glaucoma [9C61]
|
[20] |
Brimonidine |
DMQLT4N
|
Moderate |
Additive CNS depression effects by the combination of Promazine and Brimonidine. |
Glaucoma [9C61]
|
[51] |
Pilocarpine |
DMV9ADG
|
Moderate |
Antagonize the effect of Promazine when combined with Pilocarpine. |
Glaucoma [9C61]
|
[30] |
Spironolactone |
DM2AQ5N
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Spironolactone. |
Heart failure [BD10-BD1Z]
|
[21] |
Prazosin |
DMCD9YG
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Prazosin. |
Heart failure [BD10-BD1Z]
|
[21] |
Eplerenone |
DMF0NQR
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Eplerenone. |
Heart failure [BD10-BD1Z]
|
[21] |
Carvedilol |
DMHTEAO
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Carvedilol. |
Heart failure [BD10-BD1Z]
|
[21] |
Chlorothiazide |
DMLHESP
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Chlorothiazide. |
Heart failure [BD10-BD1Z]
|
[20] |
Furosemide |
DMMQ8ZG
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Furosemide. |
Heart failure [BD10-BD1Z]
|
[20] |
Amiloride |
DMRTSGP
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Amiloride. |
Heart failure [BD10-BD1Z]
|
[21] |
Bumetanide |
DMRV7H0
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Bumetanide. |
Heart failure [BD10-BD1Z]
|
[20] |
Hydroflumethiazide |
DMVPUQI
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Hydroflumethiazide. |
Heart failure [BD10-BD1Z]
|
[20] |
Procarbazine |
DMIK367
|
Moderate |
Additive CNS depression effects by the combination of Promazine and Procarbazine. |
Hodgkin lymphoma [2B30]
|
[27] |
Efavirenz |
DMC0GSJ
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Efavirenz. |
Human immunodeficiency virus disease [1C60-1C62]
|
[52] |
Saquinavir |
DMG814N
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Saquinavir. |
Human immunodeficiency virus disease [1C60-1C62]
|
[53] |
Rilpivirine |
DMJ0QOW
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Rilpivirine. |
Human immunodeficiency virus disease [1C60-1C62]
|
[13] |
Ritonavir |
DMU764S
|
Moderate |
Decreased metabolism of Promazine caused by Ritonavir mediated inhibition of CYP450 enzyme. |
Human immunodeficiency virus disease [1C60-1C62]
|
[54] |
Isosorbide mononitrate |
DMYLMU0
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Isosorbide mononitrate. |
Hydrocephalus [8D64]
|
[21] |
Cinacalcet |
DMCX0K3
|
Moderate |
Decreased metabolism of Promazine caused by Cinacalcet mediated inhibition of CYP450 enzyme. |
Hyper-parathyroidism [5A51]
|
[20] |
Eprosartan |
DM07K2I
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Eprosartan. |
Hypertension [BA00-BA04]
|
[21] |
Acebutolol |
DM0TI4U
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Acebutolol. |
Hypertension [BA00-BA04]
|
[21] |
Moexipril |
DM26E4B
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Moexipril. |
Hypertension [BA00-BA04]
|
[21] |
Bisoprolol |
DM3UZ95
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Bisoprolol. |
Hypertension [BA00-BA04]
|
[21] |
Captopril |
DM458UM
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Captopril. |
Hypertension [BA00-BA04]
|
[21] |
Trandolapril |
DM4L6EU
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Trandolapril. |
Hypertension [BA00-BA04]
|
[21] |
Methyldopa |
DM5I621
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Methyldopa. |
Hypertension [BA00-BA04]
|
[21] |
Clonidine |
DM6RZ9Q
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Clonidine. |
Hypertension [BA00-BA04]
|
[21] |
Losartan |
DM72JXH
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Losartan. |
Hypertension [BA00-BA04]
|
[21] |
Nebivolol |
DM7F1PA
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Nebivolol. |
Hypertension [BA00-BA04]
|
[21] |
Levamlodipine |
DM92S6N
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Levamlodipine. |
Hypertension [BA00-BA04]
|
[21] |
Fosinopril |
DM9NJ52
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Fosinopril. |
Hypertension [BA00-BA04]
|
[21] |
Doxazosin |
DM9PLRH
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Doxazosin. |
Hypertension [BA00-BA04]
|
[21] |
Verapamil |
DMA7PEW
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Verapamil. |
Hypertension [BA00-BA04]
|
[21] |
TAK-491 |
DMCF6SX
|
Moderate |
Additive hypotensive effects by the combination of Promazine and TAK-491. |
Hypertension [BA00-BA04]
|
[21] |
Fenoldopam |
DMFAOKP
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Fenoldopam. |
Hypertension [BA00-BA04]
|
[21] |
Indapamide |
DMGN1PW
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Indapamide. |
Hypertension [BA00-BA04]
|
[20] |
Benazepril |
DMH1M9B
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Benazepril. |
Hypertension [BA00-BA04]
|
[21] |
Labetalol |
DMK8U72
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Labetalol. |
Hypertension [BA00-BA04]
|
[21] |
Diazoxide |
DML1538
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Diazoxide. |
Hypertension [BA00-BA04]
|
[21] |
Enalapril |
DMNFUZR
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Enalapril. |
Hypertension [BA00-BA04]
|
[21] |
Perindopril |
DMOPZDT
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Perindopril. |
Hypertension [BA00-BA04]
|
[21] |
Felodipine |
DMOSW35
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Felodipine. |
Hypertension [BA00-BA04]
|
[21] |
Quinapril |
DMR8H31
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Quinapril. |
Hypertension [BA00-BA04]
|
[21] |
Telmisartan |
DMS3GX2
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Telmisartan. |
Hypertension [BA00-BA04]
|
[21] |
Irbesartan |
DMTP1DC
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Irbesartan. |
Hypertension [BA00-BA04]
|
[21] |
Hydralazine |
DMU8JGH
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Hydralazine. |
Hypertension [BA00-BA04]
|
[21] |
Lisinopril |
DMUOK4C
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Lisinopril. |
Hypertension [BA00-BA04]
|
[21] |
Hydrochlorothiazide |
DMUSZHD
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Hydrochlorothiazide. |
Hypertension [BA00-BA04]
|
[20] |
Fludrocortisone |
DMUDIR8
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Fludrocortisone. |
Hypo-osmolality/hyponatraemia [5C72]
|
[20] |
ITI-007 |
DMUQ1DO
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and ITI-007. |
Insomnia [7A00-7A0Z]
|
[17] |
Polyethylene glycol |
DM4I1JP
|
Moderate |
Increased risk of lowers seizure threshold by the combination of Promazine and Polyethylene glycol. |
Irritable bowel syndrome [DD91]
|
[13] |
Clidinium |
DMUMQZ0
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Clidinium. |
Irritable bowel syndrome [DD91]
|
[17] |
Dicyclomine |
DMZSDGX
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Dicyclomine. |
Irritable bowel syndrome [DD91]
|
[17] |
Physostigmine |
DM2N0TO
|
Moderate |
Antagonize the effect of Promazine when combined with Physostigmine. |
Lips/oral mucosa miscellaneous disorder [DA02]
|
[19] |
Crizotinib |
DM4F29C
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Crizotinib. |
Lung cancer [2C25]
|
[55] |
Porfimer Sodium |
DM7ZWNY
|
Moderate |
Increased risk of photosensitivity reactions by the combination of Promazine and Porfimer Sodium. |
Lung cancer [2C25]
|
[56] |
Ceritinib |
DMB920Z
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Ceritinib. |
Lung cancer [2C25]
|
[13] |
Osimertinib |
DMRJLAT
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Osimertinib. |
Lung cancer [2C25]
|
[57] |
Selpercatinib |
DMZR15V
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Selpercatinib. |
Lung cancer [2C25]
|
[58] |
Lumefantrine |
DM29GAD
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Lumefantrine. |
Malaria [1F40-1F45]
|
[20] |
Chloroquine |
DMSI5CB
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Chloroquine. |
Malaria [1F40-1F45]
|
[59] |
Hydroxychloroquine |
DMSIVND
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Hydroxychloroquine. |
Malaria [1F40-1F45]
|
[59] |
Quinine |
DMSWYF5
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Quinine. |
Malaria [1F40-1F45]
|
[13] |
Primaquine |
DMWQ16I
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Primaquine. |
Malaria [1F40-1F45]
|
[13] |
Inotuzumab ozogamicin |
DMAC130
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Inotuzumab ozogamicin. |
Malignant haematopoietic neoplasm [2B33]
|
[14] |
Arsenic trioxide |
DM61TA4
|
Major |
Increased risk of ventricular arrhythmias by the combination of Promazine and Arsenic trioxide. |
Mature B-cell lymphoma [2A85]
|
[60] |
Vemurafenib |
DM62UG5
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Vemurafenib. |
Melanoma [2C30]
|
[13] |
Allopregnanolone |
DMNLHAC
|
Moderate |
Additive CNS depression effects by the combination of Promazine and Allopregnanolone. |
Mental/behavioural/neurodevelopmental disorder [6E20-6E8Z]
|
[61] |
Propranolol |
DM79NTF
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Propranolol. |
Migraine [8A80]
|
[21] |
Lasmiditan |
DMXLVDT
|
Moderate |
Additive CNS depression effects by the combination of Promazine and Lasmiditan. |
Migraine [8A80]
|
[62] |
Panobinostat |
DM58WKG
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Panobinostat. |
Multiple myeloma [2A83]
|
[63] |
Thalidomide |
DM70BU5
|
Moderate |
Additive CNS depression effects by the combination of Promazine and Thalidomide. |
Multiple myeloma [2A83]
|
[14] |
Siponimod |
DM2R86O
|
Major |
Increased risk of ventricular arrhythmias by the combination of Promazine and Siponimod. |
Multiple sclerosis [8A40]
|
[20] |
Fingolimod |
DM5JVAN
|
Major |
Increased risk of ventricular arrhythmias by the combination of Promazine and Fingolimod. |
Multiple sclerosis [8A40]
|
[64] |
Ozanimod |
DMT6AM2
|
Major |
Increased risk of ventricular arrhythmias by the combination of Promazine and Ozanimod. |
Multiple sclerosis [8A40]
|
[14] |
Methoxsalen |
DME8FZ9
|
Moderate |
Increased risk of photosensitivity reactions by the combination of Promazine and Methoxsalen. |
Mycosis fungoides [2B01]
|
[20] |
Romidepsin |
DMT5GNL
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Romidepsin. |
Mycosis fungoides [2B01]
|
[28] |
Nilotinib |
DM7HXWT
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Nilotinib. |
Myeloproliferative neoplasm [2A20]
|
[13] |
Imatinib |
DM7RJXL
|
Moderate |
Decreased metabolism of Promazine caused by Imatinib mediated inhibition of CYP450 enzyme. |
Myeloproliferative neoplasm [2A20]
|
[65] |
Dasatinib |
DMJV2EK
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Dasatinib. |
Myeloproliferative neoplasm [2A20]
|
[66] |
Dextroamphetamine |
DMMIHVP
|
Moderate |
Antagonize the effect of Promazine when combined with Dextroamphetamine. |
Narcolepsy [7A20]
|
[25] |
Droperidol |
DM0DXA8
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Droperidol. |
Nausea/vomiting [MD90]
|
[13] |
Dimenhydrinate |
DM264B3
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Dimenhydrinate. |
Nausea/vomiting [MD90]
|
[17] |
Prochlorperazine |
DM53SRA
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Prochlorperazine. |
Nausea/vomiting [MD90]
|
[17] |
Promethazine |
DM6I5GR
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Promethazine. |
Nausea/vomiting [MD90]
|
[17] |
Metoclopramide |
DMFA5MY
|
Major |
Additive antidopaminergic effects by the combination of Promazine and Metoclopramide. |
Nausea/vomiting [MD90]
|
[67] |
Granisetron |
DMIUW25
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Granisetron. |
Nausea/vomiting [MD90]
|
[13] |
Ondansetron |
DMOTQ1I
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Ondansetron. |
Nausea/vomiting [MD90]
|
[13] |
Bupropion |
DM5PCS7
|
Major |
Decreased metabolism of Promazine caused by Bupropion mediated inhibition of CYP450 enzyme. |
Nicotine use disorder [6C4A]
|
[13] |
Entrectinib |
DMMPTLH
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Entrectinib. |
Non-small cell lung cancer [2C25]
|
[14] |
Phendimetrazine |
DM6TS1N
|
Moderate |
Antagonize the effect of Promazine when combined with Phendimetrazine. |
Obesity [5B80-5B81]
|
[25] |
Amfepramone |
DM9YSNQ
|
Moderate |
Antagonize the effect of Promazine when combined with Amfepramone. |
Obesity [5B80-5B81]
|
[25] |
Lorcaserin |
DMG6OYJ
|
Moderate |
Decreased metabolism of Promazine caused by Lorcaserin mediated inhibition of CYP450 enzyme. |
Obesity [5B80-5B81]
|
[68] |
Benzphetamine |
DMIJATC
|
Moderate |
Antagonize the effect of Promazine when combined with Benzphetamine. |
Obesity [5B80-5B81]
|
[25] |
Metolazone |
DMB39LO
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Metolazone. |
Oedema [MG29]
|
[20] |
Polythiazide |
DMCH80F
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Polythiazide. |
Oedema [MG29]
|
[20] |
Lofexidine |
DM1WXA6
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Lofexidine. |
Opioid use disorder [6C43]
|
[13] |
Apraclonidine |
DMO4PVE
|
Moderate |
Additive CNS depression effects by the combination of Promazine and Apraclonidine. |
Optic nerve disorder [9C40]
|
[51] |
Rucaparib |
DM9PVX8
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Rucaparib. |
Ovarian cancer [2C73]
|
[13] |
Pentazocine |
DM1XBHS
|
Major |
Additive CNS depression effects by the combination of Promazine and Pentazocine. |
Pain [MG30-MG3Z]
|
[35] |
Dextropropoxyphene |
DM23HCX
|
Major |
Additive CNS depression effects by the combination of Promazine and Dextropropoxyphene. |
Pain [MG30-MG3Z]
|
[69] |
Butorphanol |
DM5KYPJ
|
Major |
Additive CNS depression effects by the combination of Promazine and Butorphanol. |
Pain [MG30-MG3Z]
|
[35] |
Oxymorphone |
DM65AGJ
|
Major |
Additive CNS depression effects by the combination of Promazine and Oxymorphone. |
Pain [MG30-MG3Z]
|
[35] |
Levorphanol |
DMGS80V
|
Major |
Additive CNS depression effects by the combination of Promazine and Levorphanol. |
Pain [MG30-MG3Z]
|
[35] |
Flavoxate |
DMKV4NL
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Flavoxate. |
Pain [MG30-MG3Z]
|
[17] |
Nalbuphine |
DMOSQGU
|
Major |
Additive CNS depression effects by the combination of Promazine and Nalbuphine. |
Pain [MG30-MG3Z]
|
[35] |
Methamphetamine |
DMPM4SK
|
Moderate |
Antagonize the effect of Promazine when combined with Methamphetamine. |
Pain [MG30-MG3Z]
|
[70] |
Buprenorphine |
DMPRI8G
|
Major |
Additive CNS depression effects by the combination of Promazine and Buprenorphine. |
Pain [MG30-MG3Z]
|
[71] |
Hydrocodone |
DMQ2JO5
|
Major |
Additive CNS depression effects by the combination of Promazine and Hydrocodone. |
Pain [MG30-MG3Z]
|
[35] |
Meperidine |
DMX4GND
|
Major |
Additive CNS depression effects by the combination of Promazine and Meperidine. |
Pain [MG30-MG3Z]
|
[35] |
Oxycodone |
DMXLKHV
|
Major |
Additive CNS depression effects by the combination of Promazine and Oxycodone. |
Pain [MG30-MG3Z]
|
[35] |
Triclabendazole |
DMPWGBR
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Triclabendazole. |
Parasitic worm infestation [1F90]
|
[28] |
Pergolide |
DM14MAE
|
Moderate |
Antagonize the effect of Promazine when combined with Pergolide. |
Parkinsonism [8A00]
|
[72] |
Opicapone |
DM1BKA6
|
Moderate |
Antagonize the effect of Promazine when combined with Opicapone. |
Parkinsonism [8A00]
|
[73] |
Rasagiline |
DM3WKQ4
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Rasagiline. |
Parkinsonism [8A00]
|
[27] |
Biperiden |
DME78OA
|
Moderate |
Antagonize the effect of Promazine when combined with Biperiden. |
Parkinsonism [8A00]
|
[74] |
Entacapone |
DMLBVKQ
|
Moderate |
Antagonize the effect of Promazine when combined with Entacapone. |
Parkinsonism [8A00]
|
[72] |
Levodopa |
DMN3E57
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Levodopa. |
Parkinsonism [8A00]
|
[72] |
Pimavanserin |
DMR7IVC
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Pimavanserin. |
Parkinsonism [8A00]
|
[75] |
Bromocriptine |
DMVE3TK
|
Moderate |
Antagonize the effect of Promazine when combined with Bromocriptine. |
Parkinsonism [8A00]
|
[72] |
Apomorphine |
DMX38HQ
|
Moderate |
Antagonize the effect of Promazine when combined with Apomorphine. |
Parkinsonism [8A00]
|
[76] |
Methylscopolamine |
DM5VWOB
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Methylscopolamine. |
Peptic ulcer [DA61]
|
[17] |
Famotidine |
DMRL3AB
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Famotidine. |
Peptic ulcer [DA61]
|
[20] |
Macimorelin |
DMQYJIR
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Macimorelin. |
Pituitary gland disorder [5A60-5A61]
|
[77] |
Lefamulin |
DME6G97
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Lefamulin. |
Pneumonia [CA40]
|
[12] |
Hydrocortisone |
DMGEMB7
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Hydrocortisone. |
Postoperative inflammation [1A00-CA43]
|
[20] |
Degarelix |
DM3O8QY
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Degarelix. |
Prostate cancer [2C82]
|
[14] |
ABIRATERONE |
DM8V75C
|
Moderate |
Decreased metabolism of Promazine caused by ABIRATERONE mediated inhibition of CYP450 enzyme. |
Prostate cancer [2C82]
|
[78] |
Nilutamide |
DMFN07X
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Nilutamide. |
Prostate cancer [2C82]
|
[14] |
Enzalutamide |
DMGL19D
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Enzalutamide. |
Prostate cancer [2C82]
|
[14] |
Flutamide |
DMK0O7U
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Flutamide. |
Prostate cancer [2C82]
|
[14] |
Bicalutamide |
DMZMSPF
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Bicalutamide. |
Prostate cancer [2C82]
|
[14] |
Terazosin |
DM3JCVS
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Terazosin. |
Prostate hyperplasia [GA90]
|
[21] |
Tamsulosin |
DM5QF9V
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Tamsulosin. |
Prostate hyperplasia [GA90]
|
[21] |
Silodosin |
DMJSBT6
|
Moderate |
Additive hypotensive effects by the combination of Promazine and Silodosin. |
Prostate hyperplasia [GA90]
|
[21] |
Verteporfin |
DMIY6DB
|
Moderate |
Increased risk of photosensitivity reactions by the combination of Promazine and Verteporfin. |
Psoriasis [EA90]
|
[14] |
Fluphenazine |
DMIT8LX
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Fluphenazine. |
Psychotic disorder [6A20-6A25]
|
[17] |
Gatifloxacin |
DMSL679
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Gatifloxacin. |
Respiratory infection [CA07-CA4Z]
|
[79] |
Neupro |
DMHEAB1
|
Moderate |
Antagonize the effect of Promazine when combined with Neupro. |
Restless legs syndrome [7A80]
|
[72] |
Celecoxib |
DM6LOQU
|
Moderate |
Decreased metabolism of Promazine caused by Celecoxib mediated inhibition of CYP450 enzyme. |
Rheumatoid arthritis [FA20]
|
[80] |
Cyproheptadine |
DM92AH3
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Cyproheptadine. |
Rheumatoid arthritis [FA20]
|
[17] |
Quetiapine |
DM1N62C
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Quetiapine. |
Schizophrenia [6A20]
|
[13] |
Mesoridazine |
DM2ZGAN
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Mesoridazine. |
Schizophrenia [6A20]
|
[20] |
Thioridazine |
DM35M8J
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Thioridazine. |
Schizophrenia [6A20]
|
[81] |
Aripiprazole |
DM3NUMH
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Aripiprazole. |
Schizophrenia [6A20]
|
[17] |
Iloperidone |
DM6AUFY
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Iloperidone. |
Schizophrenia [6A20]
|
[13] |
Paliperidone |
DM7NPJS
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Paliperidone. |
Schizophrenia [6A20]
|
[13] |
Haloperidol |
DM96SE0
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Haloperidol. |
Schizophrenia [6A20]
|
[13] |
Molindone |
DMAH70G
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Molindone. |
Schizophrenia [6A20]
|
[17] |
Chlorpromazine |
DMBGZI3
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Chlorpromazine. |
Schizophrenia [6A20]
|
[17] |
Thiothixene |
DMDINC4
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Thiothixene. |
Schizophrenia [6A20]
|
[17] |
Trifluoperazine |
DMKBYWI
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Trifluoperazine. |
Schizophrenia [6A20]
|
[17] |
Risperidone |
DMN6DXL
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Risperidone. |
Schizophrenia [6A20]
|
[17] |
Amisulpride |
DMSJVAM
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Amisulpride. |
Schizophrenia [6A20]
|
[82] |
Asenapine |
DMSQZE2
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Asenapine. |
Schizophrenia [6A20]
|
[13] |
Pimozide |
DMW83TP
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Pimozide. |
Schizophrenia [6A20]
|
[14] |
Fentanyl |
DM8WAHT
|
Major |
Additive CNS depression effects by the combination of Promazine and Fentanyl. |
Sensation disturbance [MB40]
|
[35] |
Vardenafil |
DMTBGW8
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Vardenafil. |
Sexual dysfunction [HA00-HA01]
|
[13] |
LEE011 |
DMMX75K
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and LEE011. |
Solid tumour/cancer [2A00-2F9Z]
|
[13] |
Epirubicin |
DMPDW6T
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Epirubicin. |
Solid tumour/cancer [2A00-2F9Z]
|
[13] |
Cisplatin |
DMRHGI9
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Cisplatin. |
Solid tumour/cancer [2A00-2F9Z]
|
[20] |
Vandetanib |
DMRICNP
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Vandetanib. |
Solid tumour/cancer [2A00-2F9Z]
|
[13] |
Doxorubicin |
DMVP5YE
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Doxorubicin. |
Solid tumour/cancer [2A00-2F9Z]
|
[13] |
Pitolisant |
DM8RFNJ
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Pitolisant. |
Somnolence [MG42]
|
[13] |
Telavancin |
DM58VQX
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Telavancin. |
Staphylococcal/streptococcal disease [1B5Y]
|
[13] |
Adenosine |
DMM2NSK
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Promazine and Adenosine. |
Supraventricular tachyarrhythmia [BC81]
|
[13] |
Lenvatinib |
DMB1IU4
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Lenvatinib. |
Thyroid cancer [2D10]
|
[13] |
Cabozantinib |
DMIYDT4
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Cabozantinib. |
Thyroid cancer [2D10]
|
[14] |
Tizanidine |
DMR2IQ4
|
Moderate |
Additive CNS depression effects by the combination of Promazine and Tizanidine. |
Tonus and reflex abnormality [MB47]
|
[83] |
Tacrolimus |
DMZ7XNQ
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Tacrolimus. |
Transplant rejection [NE84]
|
[13] |
Atropine |
DMEN6X7
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Atropine. |
Unspecific substance harmful effect [NE6Z]
|
[17] |
Triprolidine |
DM7SWIA
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Triprolidine. |
Vasomotor/allergic rhinitis [CA08]
|
[17] |
Carbinoxamine |
DMCT31R
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Carbinoxamine. |
Vasomotor/allergic rhinitis [CA08]
|
[17] |
Brompheniramine |
DMFOVSD
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Brompheniramine. |
Vasomotor/allergic rhinitis [CA08]
|
[17] |
Acrivastine |
DMTIGA0
|
Moderate |
Additive anticholinergic effects by the combination of Promazine and Acrivastine. |
Vasomotor/allergic rhinitis [CA08]
|
[18] |
Procainamide |
DMNMXR8
|
Major |
Increased risk of prolong QT interval by the combination of Promazine and Procainamide. |
Ventricular tachyarrhythmia [BC71]
|
[13] |
Propafenone |
DMPIBJK
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Propafenone. |
Ventricular tachyarrhythmia [BC71]
|
[13] |
Flecainide |
DMSQDLE
|
Moderate |
Increased risk of prolong QT interval by the combination of Promazine and Flecainide. |
Ventricular tachyarrhythmia [BC71]
|
[13] |
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