Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMOI1ZF)

• Drug Name: Choline alfoscerate Drug Info
• Synonyms: Delecit (TN)

Indication

Disease Entry	ICD 11	Status	REF
Amnesia	MB21.1	Approved	[1]

• Cross-matching ID:
  PubChem CID: 657272
  ChEBI ID: CHEBI:16870
  CAS Number: CAS 28319-77-9
  TTD Drug ID: DMOI1ZF

Molecule-Related Drug Atlas

Drug(s) Targeting Muscarinic acetylcholine receptor M5 (CHRM5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Promazine	DMZAL7W	Acute intermittent hepatic porphyria	5C58.11	Approved	[5]
ACECLIDINE	DMOLNCZ	Glaucoma/ocular hypertension	9C61	Approved	[6]
Pilocarpine	DMV9ADG	Glaucoma/ocular hypertension	9C61	Approved	[7]
Anisodine	DMNOSWU	Central and peripheral nervous disease	8A04-8E7Z	Approved	[8]
Atropine	DMEN6X7	Organophosphate poisoning	NE6Z	Approved	[9]
Propiverine	DMUWBIJ	Urinary incontinence	MF50.2	Approved	[10]
Umeclidinium	DM4E8O9	Chronic obstructive pulmonary disease	CA22	Approved	[11]
Cimetropium bromide	DMZHPNE	Gastric motility disorder	DA21	Approved	[12]
Butylscopolamine	DMZKXB7	Dysmenorrhea	GA34.3	Approved	[13]
Trospium	DMX6RTG	Overactive bladder	GC50.0	Approved	[14]

Drug(s) Affected By Patatin-like phospholipase domain-containing protein 6 (PNPLA6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Selenium	DM25CGV	N. A.	N. A.	Approved	[15]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[16]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[17]
Clodronate	DM9Y6X7	Hypercalcaemia	5B91.0	Approved	[18]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[18]
Isoflurophate	DMBSK7X	Glaucoma/ocular hypertension	9C61	Approved	[19]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[20]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[21]
Sodium lauryl sulfate	DMLJ634	Constipation	DD91.1	Approved	[22]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[23]

Drug(s) Affected By Glycerophosphodiester phosphodiesterase domain-containing protein 5 (GDPD5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[24]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[25]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[26]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[17]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[27]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[28]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[29]
Azathioprine	DMMZSXQ	Lupus nephritis	4A40.0Y	Approved	[30]
Diethylstilbestrol	DMN3UXQ	Gonorrheal vaginitis	GA02	Approved	[31]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[32]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Muscarinic acetylcholine receptor M5 (CHRM5)	TTH18TF	ACM5_HUMAN	Modulator	[2]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Glycerophosphodiester phosphodiesterase domain-containing protein 5 (GDPD5)	OTUM65JL	GDPD5_HUMAN	Regulation of Drug Effects	[3]
Patatin-like phospholipase domain-containing protein 6 (PNPLA6)	OTT5T45Q	PLPL6_HUMAN	Regulation of Drug Effects	[4]

References

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