Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQ2SNL)

Drug Name
2-(carboxymethylamino)-2-oxoacetic acid Drug Info
Synonyms
N-Oxalylglycine; 5262-39-5; Oxalylglycine; Oxaloglycine; 2-((Carboxymethyl)amino)-2-oxoacetic acid; UNII-VVW38EB8YS; N-(carboxycarbonyl)glycine; N-OXALYOLGLYCINE; VVW38EB8YS; 2-oxo-3-azaglutaric acid; CHEMBL90852; Glycine, N-(carboxycarbonyl)-; CHEBI:44482; OGA; C4H5NO5; 4idz; 4nrp; 2xml; 3hqr; N-oxalyl glycine, 1a; 2oq6; 1h2k; AC1MIVD0; Glycine,N-(carboxycarbonyl)-; SCHEMBL435820; BDBM26106; CTK8F0807; DTXSID20200601; MolPort-000-141-021; ZINC1534133; N-Oxalylglycine, > 4958AE
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
3080614
ChEBI ID
CHEBI:44482
CAS Number
CAS 5262-39-5
TTD Drug ID
DMQ2SNL

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting HIF-prolyl hydroxylase 1 (HPH-1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Daprodustat DMRNGD2 Anaemia 3A90 Approved [3]
FG-4592 DM4XSQ2 Anaemia 3A90 Phase 3 [4]
BAY-85-3934 DM7NHLC Anemia 3A00-3A9Z Phase 2 [5]
Pyridine-2,4-dicarboxylic acid DM4G8WX Discovery agent N.A. Investigative [1]
Drug(s) Affected By Hexokinase-2 (HK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [6]
Epinephrine DM3KJBC Acute asthma CA23 Approved [7]
Quercetin DM3NC4M Obesity 5B81 Approved [8]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [9]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [10]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [11]
Leflunomide DMR8ONJ Arthritis FA20 Approved [12]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [14]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [16]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [17]
Quercetin DM3NC4M Obesity 5B81 Approved [8]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [18]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [19]
Quinolones DM5GVHU Bacterial infection 1A00-1C4Z Approved [20]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [21]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [22]
Testosterone DM7HUNW Hot flushes GA30 Approved [23]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [24]
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Drug(s) Affected By Hypoxia-inducible factor 1-alpha (HIF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [25]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [26]
Prednisone DM2HG4X Acute asthma CA23 Approved [27]
Triamterene DM2HU9I Congestive heart failure BD10 Approved [27]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [28]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [29]
Epinephrine DM3KJBC Acute asthma CA23 Approved [7]
Quercetin DM3NC4M Obesity 5B81 Approved [30]
Fluoxetine DM3PD2C Bipolar depression Approved [31]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [32]
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Drug(s) Affected By 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [8]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [33]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [19]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [34]
Leflunomide DMR8ONJ Arthritis FA20 Approved [12]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [35]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [14]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [36]
Ethanol DMDRQZU Chronic pain MG30 Approved [37]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [19]
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Drug(s) Affected By Protein NDRG1 (NDRG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [38]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [39]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [40]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [42]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [33]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [35]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [43]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [44]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [45]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
HIF-prolyl hydroxylase 1 (HPH-1) TTMHFRY EGLN2_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) OT25JBA3 F263_HUMAN Gene/Protein Processing [2]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) OT4SO7J4 BNIP3_HUMAN Gene/Protein Processing [2]
Hexokinase-2 (HK2) OTC0GCQO HXK2_HUMAN Gene/Protein Processing [2]
Hypoxia-inducible factor 1-alpha (HIF1A) OTADSC03 HIF1A_HUMAN Protein Interaction/Cellular Processes [2]
Protein NDRG1 (NDRG1) OTVO66BO NDRG1_HUMAN Gene/Protein Processing [2]

References

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