General Information of Drug (ID: DMT9BPN)

Drug Name
8-hydroxyguanine Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
135420630
ChEBI ID
CHEBI:52617
CAS Number
CAS 5614-64-2
TTD Drug ID
DMT9BPN

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
Drug(s) Targeting GTP cyclohydrolase-I (GCH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Guanine DMIWLJE N. A. N. A. Phase 3 [1]
ProSavin DMJ42E6 Parkinson disease 8A00.0 Phase 1/2 [2]
OXB-102 DMXF9DM Parkinson disease 8A00.0 Phase 1/2 [3]
2-Propanol, Isopropanol DML5O0H Discovery agent N.A. Investigative [4]
Guanosine-5'-Triphosphate DMV2OJX Discovery agent N.A. Investigative [5]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
GTP cyclohydrolase-I (GCH1) TTLSWP6 GCH1_HUMAN Inhibitor [1]

References

1 GTP cyclohydrolase I feedback regulatory protein-dependent and -independent inhibitors of GTP cyclohydrolase I. Arch Biochem Biophys. 2001 Apr 1;388(1):67-73.
2 Clinical pipeline report, company report or official report of Oxford BioMedica.
3 Clinical pipeline report, company report or official report of Oxford BioMedica.
4 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
5 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.