Details of the Drug
General Information of Drug (ID: DMFP6MV)
Drug Name |
Fidaxomicin
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Synonyms | Dificid (TN) | ||||||||||||||||||||||||||
Indication |
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Drug Type |
Small molecular drug
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Structure | |||||||||||||||||||||||||||
3D MOL | 2D MOL | ||||||||||||||||||||||||||
#Ro5 Violations (Lipinski): 5 | Molecular Weight (mw) | 1058 | |||||||||||||||||||||||||
Logarithm of the Partition Coefficient (xlogp) | 6.4 | ||||||||||||||||||||||||||
Rotatable Bond Count (rotbonds) | 15 | ||||||||||||||||||||||||||
Hydrogen Bond Donor Count (hbonddonor) | 7 | ||||||||||||||||||||||||||
Hydrogen Bond Acceptor Count (hbondacc) | 18 | ||||||||||||||||||||||||||
ADMET Property |
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Chemical Identifiers |
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Cross-matching ID | |||||||||||||||||||||||||||
Combinatorial Drugs (CBD) | Click to Jump to the Detailed CBD Information of This Drug | ||||||||||||||||||||||||||
Molecular Interaction Atlas of This Drug
Drug Therapeutic Target (DTT) |
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Molecular Interaction Atlas (MIA) | |||||||||||||||||||||||||||
Drug-Drug Interaction (DDI) Information of This Drug
Coadministration of a Drug Treating the Disease Different from Fidaxomicin (Comorbidity)
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Drug Inactive Ingredient(s) (DIG) and Formulation(s) of This Drug
References
1 | Fidaxomicin FDA Label | ||||
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2 | 2011 FDA drug approvals. Nat Rev Drug Discov. 2012 Feb 1;11(2):91-4. | ||||
3 | FDA Approved Drug Products: DIFICID (fidaxomicin) tablets, for oral use | ||||
4 | Russell RG, Watts NB, Ebetino FH, Rogers MJ: Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. Osteoporos Int. 2008 Jun;19(6):733-59. doi: 10.1007/s00198-007-0540-8. | ||||
5 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
6 | Cerner Multum, Inc. "Australian Product Information.". | ||||
7 | Cerner Multum, Inc. "UK Summary of Product Characteristics.". | ||||
8 | Product Information. Balversa (erdafitinib). Janssen Products, LP, Horsham, PA. | ||||
9 | Product Information. Dificid (fidaxomicin). Optimer Pharmaceuticals, San Diego, CA. | ||||
10 | Product Information. Reyvow (lasmiditan). Lilly, Eli and Company, Indianapolis, IN. | ||||
11 | Benoist G, van Oort I, et al "Drug-drug interaction potential in men treated with enzalutamide: Mind the gap." Br J Clin Pharmacol 0 (2017): epub. [PMID: 28881501] | ||||
12 | Product Information. Tavalisse (fostamatinib). Rigel Pharmaceuticals, South San Francisco, CA. | ||||
13 | EMA. European Medicines Agency. European Union "EMA - List of medicines under additional monitoring.". | ||||