Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMCZIHT)

Drug Name

Asasantin Drug Info

Synonyms

Aggrenox; Aspirin mixture with Dipyridamole; 87653-67-6; Asasantin Retard; Aspirin / Dipyridamole; aspirin, dipyridamole drug combination; TX-3301; TX 3301; C24H40N8O4.C9H8O4; Aspirin/extended-release dipyridamole; AC1L3AE0; SCHEMBL456521; DTXSID40236543; LS-178622; Benzoic acid, 2-(acetyloxy)-, mixt. with 2,2',2'',2'''-((4,8-di-1-piperidinylpyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetrakis(ethanol)

Indication

Disease Entry	ICD 11	Status	REF
Cerebrovascular ischaemia	8B1Z	Approved	[1]

Cross-matching ID

PubChem CID: 137329
CAS Number: CAS 87653-67-6
TTD Drug ID: DMCZIHT

Molecule-Related Drug Atlas

Molecule Type:

DTT

DOT

Drug Status:

Approved Drug(s)

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Drug(s) Targeting Prostaglandin G/H synthase (COX)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[3]
Diclofenac	DMPIHLS	Chronic renal failure	GB61.Z	Approved	[4]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[5]
Dexibuprofen	DMFYBD0	Ankylosing spondylitis	FA92.0	Approved	[6]
Ketorolac	DMI4EL5	Postoperative inflammation	1A00-CA43.1	Approved	[7]
Meclofenamic acid	DM05FXR	Ankylosing spondylitis	FA92.0	Approved	[8]
Oxaprozin	DM9UB0P	Osteoarthritis	FA00-FA05	Approved	[9]
Aceclofenac	DMZDF0B	Inflammation	1A00-CA43.1	Approved	[10]
Lornoxicam	DMYZFXN	Migraine	8A80	Approved	[11]
Morniflumate	DM9UTDE	Otitis media	AA80-AB0Z	Approved	[12]
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Drug(s) Affected By Integrin alpha-IIb (ITGA2B)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[2]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[13]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[14]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[15]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[13]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[16]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[17]
Abciximab	DMJO6GV	Acute disease		Approved	[18]
Tirofiban	DMQG17S	Acute coronary syndrome	BA41	Approved	[18]
Eptifibatide	DMQXTJS	Acute cardiac ischemic events	BA40.Z	Approved	[18]
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Drug(s) Affected By CD63 antigen (CD63)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[19]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[20]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[21]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[22]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[23]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[24]
Dasatinib	DMJV2EK	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive		Approved	[25]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[26]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[27]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[28]
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Drug(s) Affected By P-selectin (SELP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[29]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[20]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[30]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[31]
Amlodipine	DMBDAZV	Angina pectoris	BA40	Approved	[32]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[33]
Cimetidine	DMH61ZB	Acid-reflux disorder	DA22	Approved	[34]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[35]
Cocaine	DMSOX7I	Anaesthesia	9A78.6	Approved	[36]
Ardeparin	DMYRX8B	Deep vein thrombosis	BD71	Approved	[37]
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Drug(s) Affected By Platelet endothelial cell adhesion molecule (PECAM1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[38]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[39]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[20]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[40]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[41]
Thalidomide	DM70BU5	Adult T-cell leukemia/lymphoma		Approved	[42]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[43]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[44]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[45]
Vitamin B3	DMQVRZH	Chronic renal failure	GB61.Z	Approved	[46]
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Drug(s) Affected By Platelet glycoprotein 4 (CD36)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[47]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[48]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[20]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[31]
Tolcapone	DM8MNVO	Parkinson disease	8A00.0	Approved	[49]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[50]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[51]
Disulfiram	DMCL2OK	Alcohol dependence	6C40.2	Approved	[52]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[53]
Fenofibrate	DMFKXDY	Coronary atherosclerosis		Approved	[54]
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Drug(s) Affected By Proteinase-activated receptor 1 (F2R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[55]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[56]
Selenium	DM25CGV	N. A.	N. A.	Approved	[57]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[19]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[58]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[31]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[59]
Lenalidomide	DM6Q7U4	Adult T-cell leukemia/lymphoma		Approved	[60]
Thalidomide	DM70BU5	Adult T-cell leukemia/lymphoma		Approved	[60]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[21]
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Drug(s) Affected By CD40 ligand (CD40LG)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[61]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[62]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[31]
Atorvastatin	DMF28YC	Acute coronary syndrome	BA41	Approved	[63]
Fenofibrate	DMFKXDY	Coronary atherosclerosis		Approved	[64]
Menthol	DMG2KW7	Back pain	ME84.Z	Approved	[65]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[66]
Eptifibatide	DMQXTJS	Acute cardiac ischemic events	BA40.Z	Approved	[67]
Candesartan	DMRK8OT	Chronic heart failure	BD1Z	Approved	[64]
Gemcitabine	DMSE3I7	Anterior urethra cancer		Approved	[68]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostaglandin G/H synthase (COX)	TTK0943	PGH1_HUMAN; PGH2_HUMAN	Inhibitor	[1]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
CD40 ligand (CD40LG)	OT75Z6A6	CD40L_HUMAN	Gene/Protein Processing	[2]
CD63 antigen (CD63)	OT2UGZA9	CD63_HUMAN	Gene/Protein Processing	[2]
Integrin alpha-IIb (ITGA2B)	OT4Y17PY	ITA2B_HUMAN	Gene/Protein Processing	[2]
P-selectin (SELP)	OTWR90PK	LYAM3_HUMAN	Gene/Protein Processing	[2]
Platelet endothelial cell adhesion molecule (PECAM1)	OTXOM4D9	PECA1_HUMAN	Gene/Protein Processing	[2]
Platelet glycoprotein 4 (CD36)	OT5CZWKY	CD36_HUMAN	Gene/Protein Processing	[2]
Proteinase-activated receptor 1 (F2R)	OT4WVWBO	PAR1_HUMAN	Gene/Protein Processing	[2]

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