Details of the Drug

General Information of Drug (ID: DMRBMAU)

Drug Name
Mycophenolic acid
Synonyms
Micofenolico acido; Micofenolico acido [Spanish]; Mycophenoic acid; Mycophenolate; Mycophenolsaeure; Myfortic; mycophenolic acid; Acide mycophenolique; Acido micofenolico; Acido micofenolico [INN-Spanish]; Acidum mycophenolicum; Lilly-68618; Ly 68618; Melbex; (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid; 24280-93-1; 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid; CCRIS 5565; NSC 129185; NSC-129185; UNII-HU9DX48N0T
Indication
Disease Entry ICD 11 Status REF
Crohn disease DD70 Approved [1]
Hepatosplenic T-cell lymphoma N.A. Approved [2]
Interstitial cystitis GC00.3 Approved [3]
Large granular lymphocytic leukemia 2A90.1 Approved [2]
Leukemia N.A. Approved [4]
Lupus nephritis 4A40.0Y Approved [5]
MALT lymphoma N.A. Approved [2]
Myeloid leukaemia 2B33.1 Approved [6]
Myeloproliferative neoplasm 2A20 Approved [7]
Nodal marginal zone lymphoma 2A85.0 Approved [2]
Primary cutaneous peripheral T-cell lymphoma not otherwise specified N.A. Approved [2]
Recurrent adult burkitt lymphoma 2A85.6 Approved [2]
Small intestine lymphoma N.A. Approved [2]
Splenic marginal zone lymphoma N.A. Approved [2]
Systemic lupus erythematosus 4A40.0 Approved [8]
Testicular lymphoma N.A. Approved [2]
Classic Hodgkin lymphoma N.A. Investigative [9]
Coronavirus Disease 2019 (COVID-19) 1D6Y Investigative [10]
Middle East Respiratory Syndrome (MERS) 1D64 Investigative [11]
⏷ Show the Full List of Indication(s)
Affected Organisms
Humans and other mammals
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 320.3
Logarithm of the Partition Coefficient (xlogp) 3.2
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C17H20O6
IUPAC Name
(E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
Canonical SMILES
CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
InChI
HPNSFSBZBAHARI-RUDMXATFSA-N
InChIKey
1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+
Cross-matching ID
PubChem CID
446541
ChEBI ID
CHEBI:168396
CAS Number
483-60-3
UNII
HU9DX48N0T
DrugBank ID
DB01024
INTEDE ID
DR1119
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
MERS-CoV papain-like proteinase (PL-PRO) TTYJOLE R1AB_CVEMC (854-2740) Inhibitor [11]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [12]
Organic anion transporter 1 (SLC22A6) DTQ23VB S22A6_HUMAN Substrate [13]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
UDP-glucuronosyltransferase 2B7 (UGT2B7) DEB3CV1 UD2B7_HUMAN Substrate [14]
UDP-glucuronosyltransferase 1A9 (UGT1A9) DE85D2P UD19_HUMAN Substrate [14]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 2.665 7.7034 0.5623 19.0875
CADO-ES1 GDSC2 -0.4975 1.5342 -0.5268 38.4644
EW-22 GDSC2 -0.1872 3.2448 -0.4869 36.5406
A-673 GDSC2 -0.1332 4.7108 -0.902 37.7393
SK-ES-1 GDSC2 -0.0951 3.3793 -0.423 35.7705
EW-1 GDSC2 0.1242 2.8004 -0.0406 32.8971
CAL-72 GDSC2 0.3716 6.6716 -1.1746 36.0089
ES1 GDSC2 0.3743 4.5776 -0.3078 32.8222
SK-PN-DW GDSC2 0.4113 2.3116 0.3535 29.5011
ES8 GDSC2 0.4384 2.8445 0.2914 29.6817
SJSA-1 GDSC2 0.5608 5.902 -0.6452 33.274
NY GDSC2 0.6495 6.7035 -0.9054 33.8125
HuO9 GDSC2 0.6836 4.3244 0.1179 29.3566
EW-3 GDSC2 1.0068 4.5609 0.3748 26.5686
EW-18 GDSC2 1.0234 4.8731 0.2684 27.0396
EW-11 GDSC2 1.1426 8.2786 -1.1447 32.4891
MHH-ES-1 GDSC2 1.2877 7.1723 -0.4813 29.3732
ES7 GDSC2 1.3719 4.832 0.6519 23.4937
TC-71 GDSC2 1.4689 3.8786 1.1243 20.4528
EW-16 GDSC2 1.638 7.7132 -0.3973 27.594
MG-63 GDSC2 1.9804 9.3132 -0.854 28.1803
HOS GDSC2 2.0803 7.0977 0.3205 22.453
EW-7 GDSC2 2.1681 6.7463 0.5736 20.7717
NOS-1 [Human HNSCC] GDSC2 2.3597 8.2065 0.0377 22.8806
CHSA8926 GDSC2 2.9001 8.2738 0.4862 18.7286
CAL-78 GDSC2 3.0763 8.5715 0.4897 18.1493
ES6 GDSC2 3.1781 8.5529 0.5856 17.3085
SaOS-2 GDSC2 3.2628 11.2157 -0.6743 23.1947
U2OS GDSC2 3.3636 9.7556 0.1398 19.1051
EW-24 GDSC2 3.4441 7.0929 1.5372 10.9113
HuO-3N1 GDSC2 3.6012 7.2053 1.6078 10.0358
H-EMC-SS GDSC2 4.2409 10.3333 0.5495 14.5125
G-292 clone A141B1 GDSC2 4.463 11.9052 -0.0598 17.0577
ES4 GDSC2 4.8728 11.6603 0.364 13.9356
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC2 0.134 4.0681 -0.3862 34.387
OACP4 C GDSC2 1.3475 6.6617 -0.1846 27.8228
ESO-51 GDSC2 1.8849 5.7775 0.7583 20.8137
OACM5.1 C GDSC2 3.353 6.2515 1.883 9.0138
KYSE-50 GDSC2 3.6197 8.753 0.8504 14.5158
FLO-1 GDSC2 3.7528 8.7185 0.9738 13.434
SK-GT-4 GDSC2 3.8092 8.2415 1.2555 11.6203
ESO-26 GDSC2 4.1272 7.434 1.8922 6.9504
KYAE-1 GDSC2 5.3012 6.9855 2.7621 0.5608
⏷ Show the Full List of 9 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 3.4321 9.1519 0.4982 17.0213
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC2 -2.1095 1.4298 -2.2165 54.1096
NH-12 GDSC2 -1.5879 3.4237 -2.0644 49.4181
SiMa GDSC2 -1.2945 1.5185 -1.3623 46.4755
SK-N-DZ GDSC2 -1.2909 5.9654 -2.6184 47.6352
SK-N-BE(2)-M17 GDSC2 -1.1861 2.9645 -1.505 45.8793
Kelly GDSC2 -1.182 1.3552 -1.2278 45.3274
SJNB-10 GDSC2 -0.9886 1.518 -1.0396 43.4355
IMR-5 GDSC2 -0.7324 1.0706 -0.7441 40.7381
SJNB-14 GDSC2 -0.2377 3.9519 -0.7515 37.8184
SK-N-SH GDSC2 0.3349 4.4106 -0.2888 32.9389
TGW GDSC2 0.5895 7.8085 -1.4682 35.8757
CHP-212 GDSC2 0.6945 5.2596 -0.2356 30.9504
SK-N-FI GDSC2 1.2101 9.3243 -1.5803 33.6029
SJNB-12 GDSC2 1.2866 8.769 -1.2403 32.2262
CHP-134 GDSC2 1.3497 5.3477 0.4095 24.8875
GOTO GDSC2 1.4935 6.8855 -0.1446 27.036
GI-ME-N GDSC2 1.8153 7.032 0.099 24.5878
NB(TU)1 GDSC2 2.3483 6.5509 0.8384 18.6309
SK-N-AS GDSC2 2.7385 8.7355 0.1148 21.2018
NB1 GDSC2 3.4814 11.3604 -0.5651 22.0746
SJNB-7 GDSC2 5.1942 11.4612 0.6872 11.5124
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 3.6576 9.3824 0.5667 15.9962
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-148 GDSC2 -0.8298 1.8236 -0.9051 41.9487
DU4475 GDSC2 -0.5895 1.8277 -0.6507 39.518
CAL-51 GDSC2 -0.4653 2.8691 -0.6969 38.954
HCC1806 GDSC2 -0.4632 2.7828 -0.6751 38.861
Hs 578T GDSC2 0.0911 4.7771 -0.686 35.7829
MCF-7 GDSC2 0.4662 5.1152 -0.4179 32.8286
CAL-120 GDSC2 1.2486 11.6301 -2.6654 36.2244
OCUB-M GDSC2 1.3506 6.4551 -0.0861 27.3534
MDA-MB-468 GDSC2 1.3655 5.869 0.1952 25.923
MRK-nu-1 GDSC2 1.5607 5.3938 0.6057 22.9553
MDA-MB-231 GDSC2 1.6862 6.6074 0.175 24.7138
HDQ-P1 GDSC2 1.7552 7.3108 -0.0921 25.7479
MDA-MB-415 GDSC2 1.8976 14.1685 -3.3297 35.4554
CAMA-1 GDSC2 2.9151 8.5859 0.3437 19.4435
MDA-MB-361 GDSC2 2.9438 7.7216 0.7996 16.8408
MFM-223 GDSC2 3.0544 8.2519 0.6306 17.4441
MDA-MB-453 GDSC2 3.1224 7.7314 0.9488 15.4168
MDA-MB-175-VII GDSC2 3.541 9.0585 0.6341 15.9585
HCC1428 GDSC2 3.6957 9.3935 0.5917 15.7511
MDA-MB-436 GDSC2 3.7939 8.2437 1.2424 11.7394
CAL-85-1 GDSC2 3.881 9.0877 0.8907 13.5646
MDA-MB-157 GDSC2 3.8917 8.7091 1.0872 12.3975
Evsa-T GDSC2 4.0304 8.8722 1.1129 11.8837
BT-549 GDSC2 4.0356 9.3633 0.8735 13.2517
HCC1937 GDSC2 4.177 9.1255 1.0983 11.5953
HCC2157 GDSC2 4.2673 13.5167 -1.0106 21.7528
HCC1500 GDSC2 4.3885 12.8114 -0.5659 19.5787
AU565 GDSC2 4.3944 8.2636 1.6777 7.6412
JIMT-1 GDSC2 4.4128 13.5988 -0.9382 21.0838
BT-474 GDSC2 4.4789 7.369 2.1622 4.5788
BT-20 GDSC2 4.5061 10.928 0.455 14.3466
HCC1954 GDSC2 4.5143 13.3234 -0.7232 19.933
COLO 824 GDSC2 4.5699 9.4346 1.2329 9.8695
UACC-812 GDSC2 4.5736 12.8861 -0.4613 18.6427
EFM-192A GDSC2 4.6001 11.6727 0.158 15.6416
HCC1419 GDSC2 4.657 6.5953 2.6184 1.7612
HCC70 GDSC2 4.7073 10.8438 0.6438 12.8513
HCC38 GDSC2 4.8102 8.0189 2.0674 4.51
HCC1143 GDSC2 4.8113 7.4014 2.349 2.9443
BT-483 GDSC2 4.859 6.7686 2.6484 1.3735
T-47D GDSC2 4.9015 7.5805 2.3204 2.9595
ZR-75-30 GDSC2 5.1525 11.8636 0.4637 12.7791
EFM-19 GDSC2 5.3865 11.1377 0.9717 9.576
HCC1395 GDSC2 5.425 8.2544 2.3094 2.3041
HCC1187 GDSC2 5.9215 7.3604 2.8619 0.1229
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H4 GDSC2 -3.1894 0.458 -3.2538 63.7081
A-172 GDSC2 -0.3209 2.4731 -0.4581 37.175
8-MG-BA GDSC2 -0.2465 4.1532 -0.8274 38.1281
MOG-G-UVW GDSC2 -0.1624 2.9697 -0.3905 36.005
M059J GDSC2 0.5333 6.1287 -0.7711 33.876
SF539 GDSC2 0.6115 6.4377 -0.826 33.7062
U-251MG GDSC2 0.761 6.0495 -0.5022 31.77
GaMG GDSC2 0.7695 4.3475 0.2017 28.5386
KS-1 [Human Krukenberg tumour] GDSC2 0.8185 9.4471 -2.0144 36.3532
LNZTA3WT4 GDSC2 0.8275 5.7104 -0.2866 30.5551
GB-1 GDSC2 1.079 6.471 -0.366 29.774
YH-13 GDSC2 1.0959 5.5258 0.0704 27.7
D283 Med GDSC2 1.1241 4.9 0.3636 26.1028
Daoy GDSC2 1.1302 5.4652 0.132 27.2484
SW1783 GDSC2 1.1304 6.4215 -0.2917 29.2269
GI-1 GDSC2 1.1583 9.2165 -1.5779 33.8009
CAS-1 GDSC2 1.4063 8.5186 -1.0056 30.934
D-392MG GDSC2 1.4519 10.0504 -1.7045 33.0405
MOG-G-CCM GDSC2 1.5203 9.3561 -1.3025 31.5202
U-87MG ATCC GDSC2 1.577 6.4274 0.1517 25.2683
Becker GDSC2 1.6927 7.1879 -0.0935 25.9992
ONS-76 GDSC2 1.8932 6.5123 0.4218 22.6257
T98G GDSC2 1.924 10.5476 -1.5132 30.729
KALS-1 GDSC2 2.1994 10.3108 -1.147 28.5056
42-MG-BA GDSC2 2.2146 9.2702 -0.6189 26.3884
PFSK-1 GDSC2 2.326 6.4547 0.864 18.5632
KINGS-1 GDSC2 2.3996 15.1935 -3.399 34.0967
DBTRG-05MG GDSC2 2.5907 6.9277 0.8784 17.5537
LN-18 GDSC2 2.8488 8.2453 0.4557 19.06
D-263MG GDSC2 2.9813 9.3412 0.0239 20.8665
U-118MG GDSC2 3.0703 5.7396 1.8975 9.7736
SF268 GDSC2 3.302 7.4582 1.2372 13.1588
AM-38 GDSC2 3.4021 6.3792 1.8595 9.0204
SW1088 GDSC2 3.5029 10.5701 -0.1525 20.1294
LN-405 GDSC2 3.7377 11.7437 -0.5477 21.2599
LN-229 GDSC2 4.1354 8.0834 1.5804 8.8302
SK-MG-1 GDSC2 4.4083 10.8245 0.4331 14.7065
DK-MG GDSC2 5.6461 16.5614 -1.4749 20.2116
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC2 2.3702 6.1281 1.0638 17.2399
TGBC24TKB GDSC2 3.6262 7.4644 1.4985 10.6413
TGBC1TKB GDSC2 3.7878 13.5837 -1.4261 24.6188
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC2 1.3284 11.037 -2.3012 35.0989
ESS-1 GDSC2 1.6675 6.9351 0.0021 25.6417
KLE GDSC2 2.3553 8.986 -0.3512 24.73
MFE-280 GDSC2 2.6442 8.4509 0.1728 21.2225
AN3-CA GDSC2 3.621 12.4254 -0.983 23.4096
MFE-296 GDSC2 4.495 7.46 2.1297 4.7381
MFE-319 GDSC2 4.6069 14.0463 -1.0106 20.8819
EN GDSC2 5.625 14.7769 -0.6182 16.8521
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 129 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IM-9 GDSC2 -2.389 -1.1395 -2.389 57.3064
CML-T1 GDSC2 -2.2357 -0.9779 -2.2358 55.769
BALL-1 GDSC2 -1.8584 -0.3234 -1.8593 51.9822
MOLT-16 GDSC2 -1.8231 -0.5776 -1.8232 51.6301
Karpas-231 GDSC2 -1.8221 -0.0743 -1.8246 51.6149
JVM-3 GDSC2 -1.8197 -0.4601 -1.82 51.5961
EoL-1 GDSC2 -1.7877 0.1679 -1.7934 51.2665
MOLM-13 GDSC2 -1.7684 0.4843 -1.7827 51.0657
CTV-1 GDSC2 -1.6935 1.2089 -1.7515 50.3153
SU-DHL-5 GDSC2 -1.6841 0.2091 -1.6893 50.2347
ARH-77 GDSC2 -1.683 1.0552 -1.7271 50.2166
RPMI-8866 GDSC2 -1.6572 0.8169 -1.6839 49.9665
DG-75 GDSC2 -1.592 2.0611 -1.7567 49.3777
ATN-1 GDSC2 -1.4072 0.7918 -1.4248 47.4926
697 GDSC2 -1.3505 0.6352 -1.3607 46.9139
NALM-6 GDSC2 -1.1201 1.0233 -1.1404 44.6448
A3/Kawakami GDSC2 -1.1115 1.021 -1.1315 44.5582
Namalwa GDSC2 -1.0382 1.7961 -1.1232 44.0213
BL-41 GDSC2 -1.0049 1.6054 -1.0656 43.6253
JURL-MK1 GDSC2 -0.8979 1.8352 -0.9789 42.6368
HAL-01 GDSC2 -0.7378 1.0635 -0.7493 40.7917
WSU-NHL GDSC2 -0.7357 1.8535 -0.8087 41.0122
MOLT-4 GDSC2 -0.6675 1.9854 -0.7531 40.3859
KOPN-8 GDSC2 -0.5194 1.8352 -0.5772 38.8067
VAL GDSC2 -0.5137 2.6437 -0.7002 39.2558
H9 GDSC2 -0.4839 2.6865 -0.6769 38.9912
GR-ST GDSC2 -0.4712 4.2219 -1.0942 40.2578
BC-1 GDSC2 -0.4391 1.3849 -0.4568 37.8264
OCI-M1 GDSC2 -0.4211 3.2041 -0.7314 38.8144
ML-2 GDSC2 -0.3901 2.1758 -0.4835 37.6737
RPMI-8402 GDSC2 -0.3106 2.6228 -0.4757 37.1908
WIL2 NS GDSC2 -0.308 3.6995 -0.7487 38.2121
OCI-AML-2 GDSC2 -0.2858 0.9733 -0.2879 36.2145
AMO1 GDSC2 -0.2762 1.911 -0.3284 36.3566
P32/ISH GDSC2 -0.2722 1.6652 -0.3017 36.2101
P12-Ichikawa GDSC2 -0.2642 2.2487 -0.3596 36.4324
KE-37 GDSC2 -0.2407 2.2845 -0.3398 36.2153
RPMI-6666 GDSC2 -0.2242 2.6192 -0.3814 36.3076
YT GDSC2 -0.2063 2.1675 -0.2857 35.784
SUP-B15 GDSC2 -0.1915 1.576 -0.2117 35.3568
Jiyoye GDSC2 -0.1845 5.2645 -1.1674 38.8287
HC-1 GDSC2 -0.0811 1.406 -0.0899 34.1933
SR GDSC2 -0.0579 2.2746 -0.1424 34.3274
SCC-3 GDSC2 -0.0576 2.5813 -0.1936 34.5656
Ku812 GDSC2 -0.0533 4.1755 -0.6255 36.3352
VL51 GDSC2 -0.0354 4.5377 -0.7335 36.631
SUP-T1 GDSC2 -0.0164 3.0574 -0.2526 34.613
SUP-M2 GDSC2 0.0173 1.8858 -0.0169 33.3323
JVM-2 GDSC2 0.1321 2.5345 0.0198 32.5657
A4/Fukuda GDSC2 0.1544 2.1169 0.1043 32.0371
BV-173 GDSC2 0.2605 2.0048 0.2276 30.8871
KCL-22 GDSC2 0.2701 3.5347 -0.069 32.2821
NKM-1 GDSC2 0.2791 6.4501 -1.1727 36.4505
Jurkat GDSC2 0.3179 3.3051 0.0481 31.4854
LC4-1 GDSC2 0.3434 4.0766 -0.1621 32.3375
EB2 GDSC2 0.3472 4.1075 -0.1685 32.3469
U-698-M GDSC2 0.3578 6.49 -1.1091 35.8701
DEL GDSC2 0.3592 2.5261 0.2659 30.2024
Reh GDSC2 0.4298 3.6367 0.0745 30.7992
GA-10 GDSC2 0.4338 2.9313 0.2675 29.8252
CA46 GDSC2 0.4343 4.6586 -0.274 32.3771
RS4;11 GDSC2 0.4688 3.0527 0.2774 29.6027
JSC-1 GDSC2 0.5019 3.9466 0.0536 30.5445
WSU-DLCL2 GDSC2 0.6768 4.5134 0.0405 29.7631
LAMA-84 GDSC2 0.7112 5.0025 -0.1135 30.3215
DB GDSC2 0.7506 5.2199 -0.1604 30.3506
ALL-PO GDSC2 0.7561 4.9037 -0.0264 29.7064
Granta-519 GDSC2 0.8168 5.2717 -0.1123 29.8234
P30/OHK GDSC2 0.8325 3.7774 0.4684 26.8813
OCI-AML-5 GDSC2 0.8746 3.1019 0.7078 25.4246
NCI-H929 GDSC2 1.0323 4.2421 0.5229 25.6775
Raji GDSC2 1.063 4.3899 0.5005 25.6579
Ramos.2G6.4C10 GDSC2 1.1195 5.6868 0.0248 27.8166
MEG-01 GDSC2 1.121 5.221 0.2268 26.816
HL-60 GDSC2 1.1535 2.8413 1.0673 22.2049
JJN-3 GDSC2 1.2005 5.8783 0.0233 27.4719
MHH-PREB-1 GDSC2 1.2162 5.1476 0.3569 25.735
Hs 445 GDSC2 1.2911 5.1318 0.4416 24.9685
RPMI-8226 GDSC2 1.2996 5.8849 0.1212 26.5703
KMOE-2 GDSC2 1.3027 5.4629 0.3109 25.6
OCI-AML-3 GDSC2 1.3471 3.4836 1.1205 21.0182
SU-DHL-10 GDSC2 1.3596 4.3044 0.8501 22.4561
MOLP-8 GDSC2 1.3628 4.5531 0.7559 22.9623
CCRF-CEM GDSC2 1.3856 4.7685 0.6925 23.213
TUR GDSC2 1.4197 3.7171 1.126 20.6615
Mono-Mac-6 GDSC2 1.499 4.7024 0.8388 21.9231
TK [Human B-cell lymphoma] GDSC2 1.5823 3.5428 1.3588 18.6482
SU-DHL-8 GDSC2 1.5919 4.4819 1.0267 20.4741
L-540 GDSC2 1.6387 5.4068 0.6795 22.2318
KM-H2 GDSC2 1.649 5.6704 0.5714 22.7824
DND-41 GDSC2 1.6693 5.3431 0.7391 21.7766
MOLT-13 GDSC2 1.6906 4.0526 1.2997 18.5049
EM-2 GDSC2 1.7263 3.6068 1.4952 17.2492
Daudi GDSC2 1.7445 5.4959 0.7467 21.4321
Karpas-1106P GDSC2 1.7606 5.308 0.8476 20.7998
CESS GDSC2 1.7715 7.3456 -0.0931 25.689
K-562 GDSC2 2.0054 7.2778 0.1625 23.5456
KMS-12-BM GDSC2 2.0971 5.5183 1.0889 18.0983
ST486 GDSC2 2.1384 7.1186 0.3652 22.0036
KY821 GDSC2 2.1587 5.2024 1.2963 16.6391
RC-K8 GDSC2 2.2566 5.3387 1.3301 16.0689
Karpas-422 GDSC2 2.2589 6.3301 0.8606 18.8252
NOMO-1 GDSC2 2.3196 5.4536 1.3378 15.7898
MN-60 GDSC2 2.3873 7.9286 0.1998 21.9686
MLMA GDSC2 2.4341 7.2535 0.5747 19.8112
OPM-2 GDSC2 2.6116 5.737 1.4811 13.8776
MM1.S GDSC2 2.6484 5.5495 1.6068 12.9787
BE-13 GDSC2 2.7419 8.0097 0.4787 19.2872
ALL-SIL GDSC2 2.8475 7.61 0.7707 17.3161
PF-382 GDSC2 2.9388 6.3959 1.455 12.9476
MHH-CALL-2 GDSC2 3.0668 5.4697 2.0287 8.96
KG-1 GDSC2 3.1977 8.2273 0.7649 16.2445
SUP-HD1 GDSC2 3.2959 5.6222 2.15 7.4952
L-428 GDSC2 3.3027 6.8357 1.549 11.2483
SU-DHL-6 GDSC2 3.3981 7.6533 1.2194 12.9841
Karpas-299 GDSC2 3.4691 6.8229 1.6925 9.8765
L-363 GDSC2 3.4793 8.3823 0.9217 14.5073
P31/FUJ GDSC2 3.5029 6.4583 1.9019 8.4711
HDLM-2 GDSC2 3.5586 9.2815 0.537 16.4414
EJM GDSC2 3.5815 7.387 1.5015 10.7461
L-1236 GDSC2 3.6223 7.6544 1.4007 11.2504
Karpas-620 GDSC2 3.6591 6.7895 1.8605 8.3079
GDM-1 GDSC2 3.7209 6.5085 2.0477 6.9757
Loucy GDSC2 3.8049 8.6956 1.0262 12.9871
ME1 GDSC2 4.4388 10.4174 0.6565 13.4324
SK-MM-2 GDSC2 4.4497 7.5053 2.0789 5.1271
Karpas-45 GDSC2 4.5994 7.9756 1.9542 5.5636
U266B1 GDSC2 5.4398 8.1506 2.3606 2.0451
HH [Human lymphoma] GDSC2 6.247 8.1136 2.7196 0.2682
⏷ Show the Full List of 129 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB996-RCC GDSC2 0.0413 5.3708 -0.9698 37.0196
CAL-54 GDSC2 0.1132 7.8811 -1.9785 39.3312
BFTC-909 GDSC2 0.4141 5.0332 -0.4404 33.1783
RCC10RGB GDSC2 0.4622 6.9015 -1.1842 35.6089
ACHN GDSC2 0.5939 4.7047 -0.1209 30.9146
KMRC-20 GDSC2 1.2829 8.0802 -0.9145 31.0985
KTCTL-195 GDSC2 1.3471 8.1412 -0.8816 30.7154
786-O GDSC2 1.3853 6.1041 0.109 26.2691
SW13 GDSC2 1.7387 7.2527 -0.0801 25.7553
769-P GDSC2 1.8047 6.562 0.3122 23.5454
KMRC-1 GDSC2 1.9845 8.9795 -0.6864 27.4965
A-498 GDSC2 2.2149 9.7591 -0.8602 27.3663
A-704 GDSC2 2.3619 12.7398 -2.2092 31.3487
VMRC-RCZ GDSC2 4.1284 6.702 2.2476 4.7829
TK-10 GDSC2 4.1723 8.812 1.2493 10.7218
SN12C GDSC2 4.5694 13.8661 -0.9501 20.7328
OS-RC-2 GDSC2 6.0982 16.0317 -0.8944 16.9917
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LoVo GDSC2 -0.2744 2.3712 -0.3901 36.6231
SNU-175 GDSC2 -0.0098 3.1657 -0.2726 34.6663
HCT 15 GDSC2 0.4622 5.2633 -0.4817 33.1088
SW620 GDSC2 0.5265 5.7575 -0.6193 33.3388
LS180 GDSC2 0.5938 6.1269 -0.708 33.3552
LS513 GDSC2 0.5974 4.2062 0.0675 30.0137
RKO GDSC2 0.7273 5.1885 -0.172 30.5117
CL-11 GDSC2 0.7726 8.9984 -1.8452 36.1138
GP5d GDSC2 0.7954 8.7208 -1.6916 35.6091
MDST8 GDSC2 1.0861 4.3289 0.5483 25.3014
HCT 116 GDSC2 1.1368 6.265 -0.2145 28.8551
SNU-C5 GDSC2 1.157 4.944 0.38 25.8731
SK-CO-1 GDSC2 1.5113 4.7967 0.8124 22.0182
HT-55 GDSC2 1.5515 6.7275 -0.0136 26.1823
SNU-407 GDSC2 1.7208 6.4077 0.3026 23.9248
KM12 GDSC2 1.7705 6.3627 0.3726 23.3633
CCK-81 GDSC2 1.7945 5.4455 0.82 20.8209
LS123 GDSC2 1.9258 9.5412 -1.0162 28.9967
COLO 320HSR GDSC2 2.1217 6.2156 0.784 19.7676
C2BBe1 GDSC2 2.1431 8.4728 -0.2916 25.2157
HCC2998 GDSC2 2.2581 7.2823 0.3977 21.3956
LS411N GDSC2 2.2965 8.5125 -0.1707 24.1076
SW626 GDSC2 2.6026 8.4887 0.1171 21.6451
NCI-H716 GDSC2 2.9377 6.8305 1.238 14.2758
LS1034 GDSC2 2.9536 9.0822 0.1294 20.4278
CW-2 GDSC2 2.9975 8.3213 0.547 18.0855
NCI-H747 GDSC2 3.0814 8.1425 0.7084 16.9239
HT-29 GDSC2 3.1319 10.0005 -0.177 21.3658
SW1417 GDSC2 3.1588 8.8799 0.4058 18.3443
COLO 678 GDSC2 3.192 9.9911 -0.1215 20.9154
DiFi GDSC2 3.2347 9.2538 0.283 18.7591
COLO205 GDSC2 3.2566 5.8489 2.0036 8.536
SNU-C2B GDSC2 3.275 9.5147 0.1863 19.1358
SW948 GDSC2 3.3927 5.6843 2.1992 6.9043
SW837 GDSC2 3.5676 8.4175 0.9759 13.9393
CaR-1 GDSC2 3.595 8.5321 0.9408 14.0651
T84 GDSC2 3.6891 9.245 0.6605 15.3904
RCM-1 [Human ESC] GDSC2 3.8373 6.6953 2.0432 6.7117
SNU-C1 GDSC2 4.4512 11.8208 -0.027 16.9291
SW1116 GDSC2 4.4591 12.6263 -0.4199 18.7481
SW1463 GDSC2 4.8326 7.155 2.4698 2.2769
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 0.7916 5.452 -0.2141 30.401
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-7 GDSC2 0.8139 6.8652 -0.8118 32.7276
SK-HEP-1 GDSC2 0.8267 5.0716 -0.0196 29.3463
HLE GDSC2 1.8928 7.3909 0.001 24.7714
JHH-2 GDSC2 2.4214 8.9922 -0.2947 24.2439
SNU-398 GDSC2 2.8687 6.5511 1.3156 14.0276
JHH-4 GDSC2 3.0535 7.8381 0.8364 16.2822
Hep-G2/C3A GDSC2 3.5412 7.7958 1.265 12.299
JHH-6 GDSC2 3.6977 7.1925 1.6902 9.2651
Huh-7 GDSC2 3.706 12.1885 -0.7955 22.4066
SNU-423 GDSC2 3.7844 10.461 0.1301 17.9334
HuH-1 GDSC2 3.8488 10.6635 0.0805 18.0026
SNU-449 GDSC2 3.9182 12.4598 -0.7601 21.6668
SNU-387 GDSC2 3.9589 12.3864 -0.691 21.2627
JHH-1 GDSC2 4.9764 11.2435 0.641 12.2426
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 129 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H810 GDSC2 -1.8321 4.1064 -2.5351 51.2509
NCI-H1876 GDSC2 -1.7117 1.134 -1.7638 50.4915
SBC-3 GDSC2 -1.4187 2.9272 -1.7494 47.9351
NCI-H209 GDSC2 -1.1192 1.4985 -1.1752 44.7358
A-549 GDSC2 -0.9814 3.2889 -1.3654 44.1748
NCI-H847 GDSC2 -0.7364 3.1369 -1.0579 41.8029
Lu-139 GDSC2 -0.141 3.2907 -0.4487 36.1287
NCI-H520 GDSC2 -0.0343 4.3663 -0.6712 36.4006
Ms-1 GDSC2 0.4029 2.6571 0.2901 29.8634
NCI-H526 GDSC2 0.6131 3.4192 0.3385 28.5915
NCI-H1944 GDSC2 0.6566 4.5099 0.0202 29.9562
NCI-H1155 GDSC2 0.7157 4.8506 -0.0482 29.9982
NCI-H446 GDSC2 0.7852 5.6526 -0.3058 30.8339
DMS 273 GDSC2 0.8233 6.1584 -0.486 31.4186
COR-L311 GDSC2 0.8589 3.8331 0.4788 26.7044
NCI-H1341 GDSC2 0.9219 5.4788 -0.0897 29.2381
NCI-H1299 GDSC2 0.9636 5.5263 -0.0667 28.9424
SBC-5 GDSC2 1.0647 4.7567 0.359 26.3911
NCI-H1993 GDSC2 1.0827 6.5516 -0.3988 29.8983
NCI-H211 GDSC2 1.0865 5.3634 0.1304 27.4481
SK-MES-1 GDSC2 1.0971 8.5859 -1.3348 33.3011
NCI-H1623 GDSC2 1.1411 8.2283 -1.1222 32.4184
NCI-H1092 GDSC2 1.1515 5.8584 -0.0178 27.8805
NCI-H82 GDSC2 1.1858 4.7571 0.4867 25.1868
NCI-H1581 GDSC2 1.311 6.2085 -0.0132 27.1747
Lu-99A GDSC2 1.3269 7.329 -0.5162 29.3561
NCI-H1792 GDSC2 1.4355 7.4061 -0.4465 28.6169
COR-L95 GDSC2 1.4618 7.5724 -0.4999 28.7361
EMC-BAC-2 GDSC2 1.479 5.6257 0.4193 24.2935
NCI-H1355 GDSC2 1.5703 6.2643 0.2207 24.948
NCI-H2122 GDSC2 1.6646 4.7028 1.0119 20.2549
NCI-H2009 GDSC2 1.6762 10.9001 -1.9131 32.8225
COR-L279 GDSC2 1.692 5.1586 0.8439 21.0964
RERF-LC-Sq1 GDSC2 1.7169 5.622 0.6617 22.0149
HARA [Human squamous cell lung carcinoma] GDSC2 1.7303 6.8166 0.1193 24.8188
NCI-H2023 GDSC2 1.836 8.3455 -0.5149 27.3363
KNS-62 GDSC2 1.9038 7.2321 0.088 24.3025
DMS 53 GDSC2 1.9439 7.4827 0.0052 24.5571
HCC44 GDSC2 1.9916 7.4286 0.0765 24.027
EBC-1 GDSC2 2.0539 8.5254 -0.3997 26.0254
Lu-135 GDSC2 2.062 5.1486 1.2241 17.4365
NCI-H835 GDSC2 2.0734 8.2762 -0.2597 25.3248
CPC-N GDSC2 2.1122 6.0158 0.8699 19.3124
NCI-H524 GDSC2 2.1406 5.5451 1.1193 17.755
NCI-H1048 GDSC2 2.1478 7.0229 0.4205 21.6757
Calu-3 GDSC2 2.2206 9.7195 -0.8355 27.2491
NCI-H650 GDSC2 2.2295 9.6574 -0.7967 27.0636
Calu-6 GDSC2 2.2792 6.1539 0.9648 18.1484
NCI-H1666 GDSC2 2.3719 9.5027 -0.5919 25.7239
COLO 668 GDSC2 2.4507 6.9355 0.746 18.7959
NCI-H2085 GDSC2 2.4526 8.6273 -0.0861 23.1585
NCI-H2795 GDSC2 2.4947 8.1703 0.178 21.706
NCI-H2461 GDSC2 2.6524 9.6451 -0.4136 23.9962
NCI-H2731 GDSC2 2.7717 10.191 -0.5813 24.3374
NCI-H69 GDSC2 2.7866 6.9107 1.0639 15.8095
NCI-H23 GDSC2 3.1743 7.779 0.9692 15.1374
NCI-H2373 GDSC2 3.1973 8.1024 0.8271 15.8907
DMS 114 GDSC2 3.2479 8.9873 0.4273 17.9561
NCI-H720 GDSC2 3.2903 9.6081 0.1525 19.2617
PC-14 GDSC2 3.2968 8.1099 0.907 15.1293
COR-L23 GDSC2 3.3241 10.4245 -0.2275 21.016
NCI-H1651 GDSC2 3.3243 7.9553 1.0072 14.4628
NCI-H322M GDSC2 3.338 10.4341 -0.2207 20.9421
Lu-165 GDSC2 3.3481 6.6657 1.6718 10.3515
LC-1/sq GDSC2 3.3949 8.1476 0.9696 14.4742
NCI-H2818 GDSC2 3.4249 10.6004 -0.2319 20.7349
LCLC-103H GDSC2 3.4464 8.6319 0.7699 15.4728
HCC78 GDSC2 3.4912 7.7594 1.2427 12.5754
NCI-H1781 GDSC2 3.4929 8.4943 0.8768 14.7269
NCI-H841 GDSC2 3.4967 11.5874 -0.6661 22.4646
NCI-H1693 GDSC2 3.5094 7.7836 1.2453 12.5077
Lu-65 GDSC2 3.5994 7.1057 1.656 9.7419
NCI-H1648 GDSC2 3.6042 8.4072 1.0106 13.633
HCC15 GDSC2 3.6516 11.782 -0.6366 21.8909
NCI-H1703 GDSC2 3.6636 8.0635 1.2295 12.1708
SHP-77 GDSC2 3.6749 7.2543 1.6416 9.6268
PaCa-3 GDSC2 3.722 8.4508 1.0828 12.8819
NCI-H2087 GDSC2 3.7297 7.3294 1.6471 9.4472
UMC-11 GDSC2 3.7387 8.3775 1.1326 12.5423
NCI-H2228 GDSC2 3.7516 10.0494 0.3092 17.1064
NCI-H1793 GDSC2 3.7865 7.0922 1.8086 8.298
NCI-H1975 GDSC2 3.7882 7.9824 1.368 10.9994
NCI-H2170 GDSC2 3.8075 7.3402 1.7017 8.906
RERF-LC-KJ GDSC2 3.8478 11.5023 -0.3387 20.0134
SW1271 GDSC2 3.8652 9.8615 0.4931 15.8162
LXF 289 GDSC2 3.9085 12.3642 -0.7202 21.5255
SK-LU-1 GDSC2 3.9284 8.8183 1.0614 12.4514
VMRC-LCD GDSC2 3.9286 9.0503 0.9463 13.1177
NCI-H727 GDSC2 3.9374 9.1928 0.8823 13.4613
LCLC-97TM1 GDSC2 3.9718 7.4013 1.7953 7.9155
NCI-H2141 GDSC2 3.9768 9.3106 0.8543 13.516
HOP-62 GDSC2 3.9843 11.9376 -0.4471 20.128
NCI-H2066 GDSC2 4.0734 13.2936 -1.0523 22.4319
HCC827 GDSC2 4.1692 8.8877 1.2097 10.9635
NCI-H1915 GDSC2 4.2036 10.1484 0.6127 14.2662
COR-L105 GDSC2 4.2595 11.8846 -0.2054 18.2782
COR-L88 GDSC2 4.3284 9.8437 0.8571 12.5966
NCI-H596 GDSC2 4.359 12.1206 -0.2458 18.208
NCI-H1573 GDSC2 4.3759 7.7853 1.8958 6.373
IA-LM GDSC2 4.3765 9.9606 0.8352 12.5998
LK-2 GDSC2 4.3854 14.0614 -1.1893 22.145
EPLC-272H GDSC2 4.3907 7.1393 2.2136 4.4487
HOP-92 GDSC2 4.4037 14.6903 -1.4878 23.2089
NCI-H358 GDSC2 4.4096 9.2295 1.2182 10.3287
NCI-H513 GDSC2 4.4133 11.1926 0.255 15.6188
SW1573 GDSC2 4.4196 9.7178 0.9863 11.6416
NCI-H64 GDSC2 4.4945 11.7214 0.0549 16.418
NCI-H1688 GDSC2 4.4987 6.4248 2.6067 2.0415
NCI-H2369 GDSC2 4.516 7.6134 2.0711 5.0414
NCI-H2347 GDSC2 4.5249 8.2774 1.7609 6.8601
NCI-H196 GDSC2 4.5329 16.7119 -2.3925 25.8571
NCI-H2722 GDSC2 4.6861 9.5462 1.2603 9.4481
NCI-H2405 GDSC2 4.7379 10.6944 0.7388 12.2634
NCI-H1435 GDSC2 4.7476 11.3578 0.4213 13.9353
NCI-H2591 GDSC2 4.797 9.6366 1.2933 9.0135
NCI-H441 GDSC2 4.8118 12.1765 0.0666 15.5775
LOU-NH91 GDSC2 4.88 14.1477 -0.8537 19.57
NCI-H1563 GDSC2 4.9307 12.6494 -0.0784 15.9956
NCI-H1650 GDSC2 4.9336 9.3677 1.5136 7.4588
NCI-H226 GDSC2 4.9398 10.5363 0.9578 10.5978
NCI-H2342 GDSC2 4.9489 10.752 0.8599 11.1182
NCI-H661 GDSC2 4.9583 18.4709 -2.9358 26.3997
NCI-H522 GDSC2 4.9938 13.211 -0.3079 16.9196
NCI-H3122 GDSC2 5.0039 14.3431 -0.8574 19.2868
NCI-H2595 GDSC2 5.0164 10.8278 0.8701 10.9128
NCI-H1755 GDSC2 5.1852 10.8223 0.9879 9.9029
NCI-H1869 GDSC2 5.2407 11.5241 0.6888 11.4029
NCI-H1838 GDSC2 5.8607 18.7651 -2.3995 22.8551
NCI-H1568 GDSC2 6.0987 17.7741 -1.7411 20.1888
⏷ Show the Full List of 129 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 0.7897 4.2763 0.2495 28.2046
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EC-GI-10 GDSC2 0.1456 3.8652 -0.3067 33.9901
TE-6 GDSC2 0.7614 5.0104 -0.0636 29.8557
KYSE-150 GDSC2 0.7654 5.7409 -0.3641 31.1754
TE-5 GDSC2 1.3073 6.9554 -0.3607 28.7762
TE-15 GDSC2 1.557 5.7029 0.4638 23.7363
KYSE-270 GDSC2 1.5861 7.0542 -0.1335 26.6102
KYSE-180 GDSC2 1.6298 5.8084 0.4894 23.3037
OE33 GDSC2 2.3482 7.1853 0.5289 20.3656
KYSE-450 GDSC2 2.4221 8.7915 -0.1947 23.7796
OE21 GDSC2 2.5535 7.5988 0.5136 19.7328
TE-9 GDSC2 3.4885 8.2412 0.9997 14.0261
KYSE-410 GDSC2 3.8724 9.0007 0.9272 13.3782
T.T GDSC2 4.0645 9.9863 0.5866 14.7725
TE-1 GDSC2 4.1598 11.1571 0.0788 17.1663
OE19 GDSC2 4.1703 8.6741 1.3157 10.3337
KYSE-520 GDSC2 4.4382 9.4021 1.1545 10.6308
KYSE-140 GDSC2 4.5326 11.4999 0.1928 15.634
KYSE-70 GDSC2 4.6552 9.4013 1.3089 9.2356
TE-4 GDSC2 4.8942 7.7595 2.236 3.4265
COLO 680N GDSC2 5.0031 12.8375 -0.1179 16.0121
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A2780 GDSC2 -0.436 2.7958 -0.6485 38.6003
DOV13 GDSC2 -0.1035 4.3543 -0.7417 37.0325
TOV-21G GDSC2 0.2484 5.3146 -0.7282 35.122
TOV-112D GDSC2 0.4519 4.7262 -0.2808 32.3196
IGROV-1 GDSC2 0.879 4.2547 0.3535 27.2613
ES-2 GDSC2 0.9258 5.0079 0.1108 28.265
TYK-nu GDSC2 1.6322 8.1562 -0.6158 28.5406
OAW28 GDSC2 2.1597 9.563 -0.8132 27.3754
OC 314 GDSC2 2.2303 7.4916 0.2696 22.1688
Caov-4 GDSC2 2.4157 9.5142 -0.5585 25.4305
RMG-I GDSC2 2.6744 9.0407 -0.0935 22.4404
OVCAR-8 GDSC2 2.9267 7.9029 0.6943 17.493
OAW42 GDSC2 3.2607 9.2425 0.3105 18.5362
OVCAR-5 GDSC2 3.5218 7.6459 1.3242 11.996
OVTOKO GDSC2 3.6628 9.5937 0.4654 16.5304
SK-OV-3 GDSC2 3.7843 11.1524 -0.215 19.6164
FU-OV-1 GDSC2 3.9661 11.3661 -0.1767 18.9306
OVISE GDSC2 4.0816 11.6939 -0.249 18.9567
OV56 GDSC2 4.1136 9.9042 0.665 14.2139
OVCAR-3 GDSC2 4.4544 11.9055 -0.0665 17.1116
OVKATE GDSC2 4.4894 6.8496 2.41 3.1327
EFO-21 GDSC2 4.7732 10.0894 1.0581 10.4078
Kuramochi GDSC2 5.0921 8.698 1.9267 4.8078
OV-90 GDSC2 5.4103 19.327 -3.0138 25.6035
OVCAR-4 GDSC2 6.228 15.8295 -0.7069 15.9479
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PL4 GDSC2 0.9588 5.296 0.026 28.5257
CFPAC-1 GDSC2 1.2644 6.0397 0.0161 27.2321
PaTu 8988t GDSC2 1.2795 8.9836 -1.3502 32.6146
KP-4 GDSC2 1.5785 7.6241 -0.4118 27.8926
PSN1 GDSC2 1.6101 5.616 0.5567 23.0204
PaTu 8902 GDSC2 2.3772 8.0982 0.1071 22.4736
Panc 10.05 GDSC2 2.4329 8.9297 -0.2534 24.0145
HuP-T4 GDSC2 3.3057 5.395 2.2718 6.696
DAN-G GDSC2 3.3166 6.981 1.4879 11.5849
Panc 03.27 GDSC2 3.3943 6.469 1.8083 9.3645
Capan-1 GDSC2 3.5354 8.8534 0.732 15.4281
Panc 02.03 GDSC2 3.6508 7.2785 1.6106 9.8837
HuP-T3 GDSC2 3.7706 6.8273 1.9277 7.5985
KP-1N GDSC2 3.7904 7.6748 1.5225 10.0534
MIA PaCa-2 GDSC2 3.8152 7.792 1.4835 10.2266
HPAC GDSC2 4.0014 8.9467 1.0538 12.3039
SW1990 GDSC2 4.1774 8.8071 1.2555 10.6729
SUIT-2 GDSC2 4.3594 6.1669 2.6427 2.0593
Capan-2 GDSC2 4.4905 11.0583 0.3792 14.7827
YAPC GDSC2 4.5045 10.7029 0.5647 13.7667
SU.86.86 GDSC2 4.5215 6.5101 2.5817 2.1401
KP-3 GDSC2 4.525 9.6412 1.1002 10.7386
KP-2 GDSC2 4.6423 10.5393 0.7457 12.4515
Hs 766T GDSC2 4.6762 8.9811 1.5259 7.9237
Panc 08.13 GDSC2 4.7206 12.3589 -0.0905 16.5613
BxPC-3 GDSC2 4.7443 8.6478 1.7307 6.5831
HPAF-II GDSC2 4.7541 14.098 -0.924 20.1664
Panc 04.03 GDSC2 4.8094 8.3936 1.8926 5.5144
AsPC-1 GDSC2 5.0836 11.817 0.438 13.0671
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC2 1.4999 8.3991 -0.8588 30.0191
NCI-H2052 GDSC2 1.6322 5.7607 0.5135 23.1638
MSTO-211H GDSC2 2.8729 9.1823 0.0096 21.2856
NCI-H2452 GDSC2 4.2796 15.6598 -2.0682 25.4893
IST-Mes1 GDSC2 4.3721 12.946 -0.6453 19.9656
NCI-H28 GDSC2 4.5384 9.1564 1.3458 9.2837
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC2 1.5871 9.0925 -1.1117 30.6083
VCaP GDSC2 2.7773 8.0288 0.5005 19.0518
22Rv1 GDSC2 3.3803 8.6757 0.6935 16.098
PC-3 GDSC2 4.5047 8.928 1.4329 8.8484
DU145 GDSC2 4.5112 10.2982 0.7685 12.6409
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 1.0958 4.2878 0.5741 25.1203
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
WM115 GDSC2 -0.5827 5.8111 -1.8064 42.5351
RPMI-7951 GDSC2 0.3678 6.1497 -0.9513 35.3064
A101D GDSC2 0.3704 4.9748 -0.4639 33.4919
A-375 GDSC2 0.3914 4.5748 -0.2885 32.6533
LOX-IMVI GDSC2 0.4724 3.7419 0.0881 30.5228
SK-MEL-24 GDSC2 0.7237 7.8606 -1.359 34.9601
A2058 GDSC2 1.0408 7.3566 -0.8109 31.728
IST-MEL1 GDSC2 1.2883 5.5393 0.2627 25.9082
WM1552C GDSC2 1.3091 5.2942 0.3907 25.1589
SH-4 GDSC2 1.5563 6.3133 0.1841 25.1897
IGR-37 GDSC2 1.5626 9.2826 -1.2271 31.1039
SK-MEL-1 GDSC2 1.66 11.6023 -2.2735 33.8499
IGR-1 GDSC2 1.6862 5.863 0.521 22.9066
WM793 GDSC2 1.7626 6.4605 0.3189 23.6756
WT2-iPS GDSC2 1.8173 7.7662 -0.2518 26.2493
GAK GDSC2 1.9141 5.7133 0.817 20.3686
HT-144 GDSC2 2.5653 7.4203 0.6125 19.1482
COLO 679 GDSC2 2.5967 7.4355 0.6334 18.9252
M14 GDSC2 2.9292 7.3135 0.9901 15.7819
CHL-1 GDSC2 3.0174 8.7004 0.3749 18.9517
WM35 GDSC2 3.2657 6.423 1.7243 10.2658
HMV-II GDSC2 3.3748 8.4121 0.8207 15.394
G-361 GDSC2 3.697 6.9117 1.8293 8.4026
WM278 GDSC2 3.8524 9.3742 0.7257 14.575
COLO 792 GDSC2 4.032 8.7965 1.1515 11.6531
MeWo GDSC2 4.1868 6.9893 2.1493 5.252
UACC-257 GDSC2 4.2255 8.0786 1.6481 8.206
SK-MEL-2 GDSC2 4.3005 5.6216 2.8488 1.082
Mel JuSo GDSC2 4.3122 8.38 1.5632 8.5154
COLO 829 GDSC2 4.9771 7.1372 2.5532 1.6802
UACC-62 GDSC2 5.0686 12.1675 0.2568 14.0268
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 633.T GDSC2 -2.3591 1.2944 -2.4648 56.3255
SW982 GDSC2 -0.6296 4.5983 -1.3959 41.9728
KYM-1 GDSC2 -0.6061 4.2503 -1.2501 41.4846
SK-LMS-1 GDSC2 -0.5102 4.4392 -1.211 40.8058
VA-ES-BJ GDSC2 0.6907 7.5754 -1.2599 34.8012
MES-SA GDSC2 1.5302 5.6653 0.4536 23.9003
SK-UT-1 GDSC2 1.6019 8.8758 -0.9925 30.1211
EW-8 GDSC2 1.6519 4.4407 1.1067 19.7677
G-401 GDSC2 1.9759 7.251 0.1474 23.7323
Rh41 GDSC2 2.0209 6.1686 0.7087 20.5702
A-204 GDSC2 2.1026 9.5441 -0.8558 27.7464
G-402 GDSC2 2.2034 7.7329 0.1267 22.9955
HT-1080 GDSC2 2.8533 7.5612 0.8001 17.1293
Rh30 GDSC2 3.0572 7.4625 1.0271 15.1593
RKN GDSC2 3.0768 9.5048 0.0239 20.5647
RD GDSC2 3.0798 8.376 0.5904 17.5873
MFH-ino GDSC2 3.5888 11.5662 -0.58 21.8269
SW872 GDSC2 4.1173 16.4098 -2.5715 27.4091
GCT GDSC2 4.4427 6.887 2.3643 3.4744
SW684 GDSC2 4.6927 14.7068 -1.2724 21.6865
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AGS GDSC2 -0.9564 3.1384 -1.2983 43.8633
23132/87 GDSC2 -0.0989 3.3579 -0.4212 35.7833
HGC-27 GDSC2 0.4384 4.8685 -0.3501 32.6826
GCIY GDSC2 0.5533 5.2613 -0.3849 32.2667
HSC-39 GDSC2 0.6951 3.61 0.3716 28.0298
RF-48 GDSC2 0.9579 5.5384 -0.0778 29.0201
SNU-5 GDSC2 1.0216 6.0575 -0.2387 29.4687
Hs 746.T GDSC2 1.1796 7.1588 -0.5816 30.2421
NUGC-3 GDSC2 1.3012 9.6512 -1.652 33.4596
SNU-1 GDSC2 1.415 6.0651 0.1566 25.9089
OCUM-1 GDSC2 2.2049 8.5347 -0.2653 24.8732
ECC10 GDSC2 2.262 5.6234 1.2014 16.8169
MKN28 GDSC2 2.6242 7.7061 0.5243 19.4334
MKN1 GDSC2 2.6688 5.9704 1.4205 14.0517
KATO III GDSC2 3.0496 8.9105 0.2976 19.2574
RERF-GC-1B GDSC2 3.308 8.3785 0.782 15.8136
NCI-N87 GDSC2 3.4321 9.1498 0.4993 17.0158
MKN45 GDSC2 3.4656 6.9302 1.6361 10.2374
IM95 GDSC2 3.6606 6.412 2.0492 7.1224
SK-GT-2 GDSC2 3.8901 9.629 0.6285 15.0114
TGBC11TKB GDSC2 4.0752 8.1516 1.5025 9.4488
Fu97 GDSC2 4.229 8.3796 1.5034 9.0698
NUGC-4 GDSC2 5.1023 13.1506 -0.1992 16.1615
SNG-M GDSC2 -0.6049 4.9131 -1.4833 42.0174
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC2 -2.1595 1.0403 -2.2255 54.6842
ASH-3 GDSC2 0.7995 6.4227 -0.6274 32.093
CAL-62 GDSC2 1.1512 5.3372 0.2088 26.7742
BHT-101 GDSC2 1.2261 7.52 -0.7048 30.5366
K5 GDSC2 1.2717 8.5235 -1.1368 31.9353
WRO GDSC2 2.4177 9.4741 -0.5368 25.3305
B-CPAP GDSC2 2.5189 7.4673 0.5471 19.6685
CGTH-W-1 GDSC2 2.6202 7.0707 0.8348 17.7046
8505C GDSC2 3.2256 9.8566 -0.026 20.3493
HTC-C3 GDSC2 3.5016 8.1249 1.0685 13.5841
TT GDSC2 4.1926 9.3674 0.9906 12.1784
8305C GDSC2 4.3817 9.6026 1.0151 11.5692
TT2609-C02 GDSC2 4.7262 9.0256 1.5385 7.7438
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB49-HNC GDSC2 -0.5868 5.8745 -1.8362 42.6123
HO-1-N-1 GDSC2 -0.3498 2.811 -0.5581 37.7488
Detroit 562 GDSC2 -0.0484 4.7914 -0.8409 37.0736
HO-1-u-1 GDSC2 0.629 6.397 -0.7901 33.4944
NCI-H3118 GDSC2 0.6436 5.6755 -0.4627 32.1572
HSC-2 GDSC2 0.7138 6.6362 -0.8099 33.1744
SAS GDSC2 0.7693 6.5654 -0.7218 32.5934
Ca9-22 GDSC2 0.9032 5.6656 -0.1891 29.7774
CAL-27 GDSC2 1.3185 7.2104 -0.4688 29.1925
JHU-022 GDSC2 1.4078 9.3373 -1.3993 32.27
HSC-3 GDSC2 1.5374 6.343 0.1515 25.4302
FaDu GDSC2 1.6608 7.6864 -0.3626 27.3527
SAT [Human HNSCC] GDSC2 1.9428 12.3089 -2.367 33.1299
BICR 78 GDSC2 1.9534 7.2941 0.1053 24.028
SCC-15 GDSC2 2.0329 7.3321 0.1622 23.4438
OSC-20 GDSC2 2.1847 7.626 0.1616 22.8876
SKN-3 GDSC2 2.6317 6.1159 1.3149 14.8215
BICR 10 GDSC2 2.9842 8.1979 0.5971 17.8515
CAL-33 GDSC2 2.9903 10.0952 -0.3449 22.5898
PCI-30 GDSC2 3.0043 8.7355 0.3461 19.1458
SCC-9 GDSC2 3.037 9.9277 -0.2213 21.8708
DOK GDSC2 3.1554 11.822 -1.0677 25.11
UPCI-SCC-090 GDSC2 4.0239 8.0383 1.5201 9.4691
BICR 22 GDSC2 4.3218 10.8368 0.3617 15.301
SCC-4 GDSC2 4.6986 9.6898 1.1995 9.7701
HSC-4 GDSC2 4.7825 13.8599 -0.7849 19.5219
LB771-HNC GDSC2 4.9862 11.1027 0.7161 11.8174
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-905 GDSC2 -0.346 4.9919 -1.235 39.9144
639V GDSC2 0.7895 3.6936 0.4484 27.1869
647V GDSC2 0.9492 5.1595 0.073 28.3428
5637 GDSC2 1.3453 5.9157 0.1537 26.2156
CAL-29 GDSC2 1.5009 8.4492 -0.882 30.1031
KU-19-19 GDSC2 1.8413 5.9565 0.6321 21.6864
J82 GDSC2 1.8841 9.9194 -1.2403 29.955
SW1710 GDSC2 2.2319 9.7113 -0.8212 27.1526
UM-UC-3 GDSC2 2.4268 6.3359 1.0166 17.3167
HT-1197 GDSC2 2.444 9.8857 -0.7176 26.001
RT-4 GDSC2 3.3213 6.1842 1.8902 9.0603
SW780 GDSC2 3.334 7.0164 1.4847 11.5537
RT-112 GDSC2 4.0917 9.4369 0.8799 13.069
TCCSUP GDSC2 4.3806 7.7924 1.8956 6.3643
HT-1376 GDSC2 5.1963 7.9281 2.3296 2.4949
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PA-1 GDSC2 -1.0415 4.3919 -1.7699 45.2595
NT2-D1 GDSC2 -0.8976 3.8935 -1.4509 43.7794
KGN GDSC2 -0.8083 3.8236 -1.3318 42.9482
NEC8 GDSC2 -0.5635 1.8763 -0.6287 39.2757
CAL-39 GDSC2 -0.1282 4.5009 -0.8203 37.4403
C-4-I GDSC2 -0.1219 2.3521 -0.223 35.0435
TC-YIK GDSC2 0.4015 3.1733 0.1741 30.4513
BPH-1 GDSC2 0.4223 5.6171 -0.6691 34.0352
HEY GDSC2 0.666 4.5345 0.0209 29.9082
PWR-1E GDSC2 0.733 3.9579 0.3005 28.2131
C-33 A GDSC2 1.0868 5.1817 0.2077 27.063
ME-180 GDSC2 1.3072 7.7501 -0.7342 30.3154
MS751 GDSC2 1.5918 7.3734 -0.2794 27.2558
DSH1 GDSC2 2.0688 4.7256 1.4205 16.25
LB831-BLC GDSC2 2.4225 6.2217 1.068 17.0288
SKG-IIIa GDSC2 2.5978 11.8546 -1.5619 28.6232
Ca Ski GDSC2 2.6963 8.2006 0.3434 20.1627
SiSo GDSC2 3.2254 7.869 0.9675 14.9918
OVMIU GDSC2 3.3568 8.9532 0.5353 17.0433
DoTc2 4510 GDSC2 3.4009 10.3026 -0.1029 20.1931
SKN GDSC2 3.5838 8.3641 1.0156 13.6609
HEC-1 GDSC2 4.0203 9.4987 0.7945 13.7389
SW756 GDSC2 4.0822 7.2931 1.9288 6.8311
OVCA420 GDSC2 4.2553 10.291 0.5814 14.3034
SiHa GDSC2 4.3085 12.8194 -0.6318 20.0727
HT-3 GDSC2 4.444 9.6421 1.0412 11.2695
PEO1 GDSC2 4.4774 9.5119 1.1291 10.6849
HeLa GDSC2 4.5547 14.9555 -1.5021 22.8791
NCC-IT GDSC2 5.1081 7.3576 2.5266 1.654
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug

Drug-Drug Interaction (DDI) Information of This Drug

Coadministration of a Drug Treating the Disease Different from Mycophenolic acid (Comorbidity)
DDI Drug Name DDI Drug ID Severity Mechanism Comorbidity REF
Sodium bicarbonate DMMU6BJ Moderate Decreased absorption of Mycophenolic acid due to altered gastric pH caused by Sodium bicarbonate. Acidosis [5C73] [15]
Clindamycin DM15HL8 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Clindamycin. Acne vulgaris [ED80] [16]
Cefuroxime DMSIMD8 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefuroxime. Acute bronchitis [CA42] [16]
Paromomycin DM1AGXN Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Paromomycin. Amoebiasis [1A36] [16]
Cefamandole DMNEXZF Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefamandole. Anaerobic bacterial infection [1A00-1A09] [16]
Aminophylline DML2NIB Minor Increased plasma concentration of Mycophenolic acid and Aminophylline due to competitive binding of plasma proteins. Asthma [CA23] [16]
Roflumilast DMPGHY8 Moderate Additive immunosuppressive effects by the combination of Mycophenolic acid and Roflumilast. Asthma [CA23] [17]
Cefotetan DM07TX3 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefotetan. Bacterial infection [1A00-1C4Z] [16]
Ofloxacin DM0VQN3 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Ofloxacin. Bacterial infection [1A00-1C4Z] [16]
Oritavancin DM28D05 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Oritavancin. Bacterial infection [1A00-1C4Z] [16]
Kanamycin DM2DMPO Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Kanamycin. Bacterial infection [1A00-1C4Z] [16]
Ceftizoxime DM3VOGS Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Ceftizoxime. Bacterial infection [1A00-1C4Z] [16]
Dalfopristin DM4LTKV Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Dalfopristin. Bacterial infection [1A00-1C4Z] [16]
Clarithromycin DM4M1SG Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Clarithromycin. Bacterial infection [1A00-1C4Z] [16]
Ticarcillin DM4ME02 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Ticarcillin. Bacterial infection [1A00-1C4Z] [16]
Cefoperazone DM53PV8 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefoperazone. Bacterial infection [1A00-1C4Z] [16]
Cefprozil DM7DSYP Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefprozil. Bacterial infection [1A00-1C4Z] [16]
Sparfloxacin DMB4HCT Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Sparfloxacin. Bacterial infection [1A00-1C4Z] [16]
Ceftriaxone DMCEW64 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Ceftriaxone. Bacterial infection [1A00-1C4Z] [16]
Streptomycin DME1LQN Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Streptomycin. Bacterial infection [1A00-1C4Z] [16]
Dalbavancin DMGMNH3 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Dalbavancin. Bacterial infection [1A00-1C4Z] [16]
Gemifloxacin DMHT34O Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Gemifloxacin. Bacterial infection [1A00-1C4Z] [16]
Cefepime DMHVWIK Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefepime. Bacterial infection [1A00-1C4Z] [16]
Imipenem DMI9FBP Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Imipenem. Bacterial infection [1A00-1C4Z] [16]
Meticillin DMIKHN0 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Meticillin. Bacterial infection [1A00-1C4Z] [16]
Norfloxacin DMIZ6W2 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Norfloxacin. Bacterial infection [1A00-1C4Z] [16]
ABT-492 DMJFD2I Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by ABT-492. Bacterial infection [1A00-1C4Z] [16]
Cefpodoxime DMJUNY5 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefpodoxime. Bacterial infection [1A00-1C4Z] [16]
Cefadroxil DMMC345 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefadroxil. Bacterial infection [1A00-1C4Z] [16]
Bacampicillin DMP54C7 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Bacampicillin. Bacterial infection [1A00-1C4Z] [16]
Cefazolin DMPDYFR Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefazolin. Bacterial infection [1A00-1C4Z] [16]
Novobiocin DMRFWGK Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Novobiocin. Bacterial infection [1A00-1C4Z] [16]
Levofloxacin DMS60RB Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Levofloxacin. Bacterial infection [1A00-1C4Z] [16]
Cefditoren DMSUVM1 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefditoren. Bacterial infection [1A00-1C4Z] [16]
Cefonicid DMTX2BH Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefonicid. Bacterial infection [1A00-1C4Z] [16]
Cefradine DMUNSWV Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefradine. Bacterial infection [1A00-1C4Z] [16]
Cloxacillin DMUTL7O Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cloxacillin. Bacterial infection [1A00-1C4Z] [16]
Amoxicillin DMUYNEI Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Amoxicillin. Bacterial infection [1A00-1C4Z] [16]
Troleandomycin DMUZNIG Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Troleandomycin. Bacterial infection [1A00-1C4Z] [16]
Cefoxitin DMY8NC4 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefoxitin. Bacterial infection [1A00-1C4Z] [16]
Ceftibuten DMWV2AG Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Ceftibuten. Bronchitis [CA20] [16]
Oxtriphylline DMLHSE3 Minor Increased plasma concentration of Mycophenolic acid and Oxtriphylline due to competitive binding of plasma proteins. Cough [MD12] [16]
SODIUM CITRATE DMHPD2Y Moderate Decreased absorption of Mycophenolic acid due to altered gastric pH caused by SODIUM CITRATE. Discovery agent [N.A.] [15]
Benzylpenicillin DMS9503 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Benzylpenicillin. Discovery agent [N.A.] [16]
Fosphenytoin DMOX3LB Minor Increased plasma concentration of Mycophenolic acid and Fosphenytoin due to competitive binding of plasma proteins. Epilepsy/seizure [8A61-8A6Z] [16]
Lincomycin DMVTHER Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Lincomycin. Gram-positive bacterial infection [1B74-1F40] [16]
Rifampin DMA8J1G Major Increased metabolism of Mycophenolic acid caused by Rifampin mediated induction of UGT. HIV-infected patients with tuberculosis [1B10-1B14] [17]
Teriflunomide DMQ2FKJ Major Additive myelosuppressive effects by the combination of Mycophenolic acid and Teriflunomide. Hyper-lipoproteinaemia [5C80] [18]
TP-434 DM5A31S Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by TP-434. Infectious gastroenteritis/colitis [1A40] [16]
Denosumab DMNI0KO Moderate Additive myelosuppressive effects by the combination of Mycophenolic acid and Denosumab. Low bone mass disorder [FB83] [19]
PF-06463922 DMKM7EW Moderate Increased metabolism of Mycophenolic acid caused by PF-06463922 mediated induction of UGT. Lung cancer [2C25] [20]
Sulphadoxine DMZI2UF Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Sulphadoxine. Malaria [1F40-1F45] [16]
Lanthanum carbonate DMMJQSH Moderate Decreased absorption of Mycophenolic acid due to formation of complexes caused by Lanthanum carbonate. Mineral absorption/transport disorder [5C64] [21]
Tecfidera DM2OVDT Moderate Additive immunosuppressive effects by the combination of Mycophenolic acid and Tecfidera. Multiple sclerosis [8A40] [22]
Siponimod DM2R86O Major Additive immunosuppressive effects by the combination of Mycophenolic acid and Siponimod. Multiple sclerosis [8A40] [20]
Fingolimod DM5JVAN Major Additive immunosuppressive effects by the combination of Mycophenolic acid and Fingolimod. Multiple sclerosis [8A40] [23]
Ocrelizumab DMEZ2KH Moderate Additive immunosuppressive effects by the combination of Mycophenolic acid and Ocrelizumab. Multiple sclerosis [8A40] [24]
Ozanimod DMT6AM2 Major Additive immunosuppressive effects by the combination of Mycophenolic acid and Ozanimod. Multiple sclerosis [8A40] [17]
Gatifloxacin DMSL679 Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Gatifloxacin. Respiratory infection [CA07-CA4Z] [16]
Colistimethate DMZ9BMU Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Colistimethate. Respiratory infection [CA07-CA4Z] [16]
Canakinumab DM8HLO5 Moderate Additive immunosuppressive effects by the combination of Mycophenolic acid and Canakinumab. Rheumatoid arthritis [FA20] [25]
Rilonacept DMGLUQS Moderate Additive immunosuppressive effects by the combination of Mycophenolic acid and Rilonacept. Rheumatoid arthritis [FA20] [25]
Golimumab DMHZV7X Major Additive immunosuppressive effects by the combination of Mycophenolic acid and Golimumab. Rheumatoid arthritis [FA20] [26]
Leflunomide DMR8ONJ Major Additive myelosuppressive effects by the combination of Mycophenolic acid and Leflunomide. Rheumatoid arthritis [FA20] [18]
Anthrax vaccine DM9GSWY Moderate Antagonize the effect of Mycophenolic acid when combined with Anthrax vaccine. Sepsis [1G40-1G41] [27]
Cephapirin DMV2JNY Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Cephapirin. Sepsis [1G40-1G41] [16]
Tedizolid DMG2SKR Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Tedizolid. Skin and skin-structure infection [1F28-1G0Z] [16]
Pitolisant DM8RFNJ Moderate Increased metabolism of Mycophenolic acid caused by Pitolisant mediated induction of UGT. Somnolence [MG42] [17]
Doripenem DM9UCJK Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Doripenem. Urinary tract infection [GC08] [16]
Plazomicin DMKMBES Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Plazomicin. Urinary tract infection [GC08] [16]
Secnidazole DMJ18YL Moderate Altered absorption of Mycophenolic acid due to GI flora changes caused by Secnidazole. Vaginal discharge [MF3A] [16]
⏷ Show the Full List of 71 DDI Information of This Drug

References

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25 Product Information. Arcalyst (rilonacept). Regeneron Pharmaceuticals Inc, Tarrytown, NY.
26 Product Information. Cimzia (certolizumab). UCB Pharma Inc, Smyrna, GA.
27 CDC. Centers for Disease Control and Prevention/ "Recommendations of the advisory committtee on immunization practices (ACIP): use of vaccines and immune globulins in persons with altered immunocompetence." MMWR Morb Mortal Wkly Rep 42(RR-04) (1993): 1-18. [PMID: 20300058]