Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJ85FS)

• Drug Name: Glutathione-S-S-glutathione Drug Info
• Synonyms: oxiglutatione; glutathione disulfide; GSSG; oxidized glutathione; Glutathione disulphide; L-Glutathione oxidized; Glutathione-ssg; Glutathione, oxidized; Oxigluthione; glutathione oxidized; Glutathone disulfide; Bi(glutathion-S-yl); Oxidized L-glutathione; L-Oxidized glutathione; L(-)-Glutathione; Oxiglutatione [INN]; S,S'-Ethylenebis(glutathione); Oxiglutationum [INN-Latin]; Oxiglutationa [INN-Spanish]; CCRIS 780; OXIDIZED GLUTATHIONE DISULFIDE; Glutathiol; UNII-ULW86O013H
• Cross-matching ID:
  PubChem CID: 65359
  ChEBI ID: CHEBI:17858
  CAS Number: CAS 27025-41-8
  TTD Drug ID: DMJ85FS
  VARIDT Drug ID: DR01698

Molecule-Related Drug Atlas

Drug(s) Transported By Multidrug resistance-associated protein 1 (ABCC1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[4]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[5]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[6]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[7]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[8]
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[9]
Irinotecan	DMP6SC2	Adenocarcinoma	2D40	Approved	[10]
Glutathione	DMAHMT9	Human immunodeficiency virus infection	1C62	Approved	[11]
Phenytoin	DMNOKBV	Epilepsy	8A60-8A68	Approved	[12]
Daunorubicin	DMQUSBT	Acute monocytic leukemia		Approved	[13]

Drug(s) Transported By Multidrug resistance-associated protein 2 (ABCC2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[14]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[15]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[16]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[17]
Dinoprostone	DMTYOPD	Medical abortion	JA00.1Z	Approved	[18]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[19]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[20]
Sulfasalazine	DMICA9H	Irritable bowel syndrome	DD91.0	Approved	[21]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[22]
Oxaliplatin	DMQNWRD	Adenocarcinoma	2D40	Approved	[23]

Drug(s) Transported By Multidrug resistance-associated protein 3 (ABCC3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[24]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[5]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[25]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[26]
Ezetimibe	DM7A8TW	Atherosclerosis	BD40	Approved	[27]
Glibenclamide	DM8JXPZ	Diabetic complication	5A2Y	Approved	[28]
Morphine	DMRMS0L	Advanced cancer	2A00-2F9Z	Approved	[29]
Cefadroxil	DMMC345	Bacterial infection	1A00-1C4Z	Approved	[30]
Teniposide	DMLW57T	Acute lymphoblastic leukaemia	2A85	Approved	[31]
Fexofenadine	DM17ONX	Allergic rhinitis	CA08.0	Approved	[32]

Molecular Interaction Atlas of This Drug

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Multidrug resistance-associated protein 3 (ABCC3)	DTQ3ZHF	MRP3_HUMAN	Substrate	[1]
Multidrug resistance-associated protein 2 (ABCC2)	DTFI42L	MRP2_HUMAN	Substrate	[2]
Multidrug resistance-associated protein 1 (ABCC1)	DTSYQGK	MRP1_HUMAN	Substrate	[3]

References

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• [23] Multidrug Resistance-Associated Protein 2 (MRP2) Mediated Transport of Oxaliplatin-Derived Platinum in Membrane Vesicles. PLoS One. 2015 Jul 1;10(7):e0130727.
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