Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMOPGHQ)

Drug Name
Indiplon Drug Info
Synonyms NBI 34060; NBI-34060; Indiplon (USAN/INN); N-methyl-N-[3-[3-(thiophene-2-carbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]acetamide
Indication
Disease Entry ICD 11 Status REF
Fibromyalgia MG30.01 Approved [1]
Insomnia 7A00-7A0Z Approved [1]
Cross-matching ID
PubChem CID
6450813
CAS Number
CAS 325715-02-4
TTD Drug ID
DMOPGHQ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting GABA(A) receptor alpha-1 (GABRA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [3]
Zolpidem DMWOSKJ Insomnia 7A00-7A0Z Approved [4]
Methoxyflurane DML0RAE Anaesthesia 9A78.6 Approved [3]
Nitrazepam DMEGIQ6 Epilepsy 8A60-8A68 Approved [3]
Allopregnanolone DMNLHAC Depression 6A70-6A7Z approved [5]
Clobazam - Lundbeck DMW1OQ0 Anxiety disorder 6B00-6B0Z Approved [3]
Hexobarbital DMQ314B Anaesthesia 9A78.6 Approved [3]
THIOCOLCHICOSIDE DMEPWYA Muscle spasm MB47.3 Approved [6]
Meprobamate DMHM93Y Anxiety Approved [3]
Zaleplon DMGFWSM Insomnia 7A00-7A0Z Approved [7]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
GABA(A) receptor alpha-1 (GABRA1) TT1MPAY GBRA1_HUMAN Agonist [2]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4221).
2 Emerging therapies for fibromyalgia. Expert Opin Emerg Drugs. 2008 Mar;13(1):53-62.
3 DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6.
4 Zolpidem, a selective GABA(A) receptor alpha1 subunit agonist, induces comparable Fos expression in oxytocinergic neurons of the hypothalamic paraventricular and accessory but not supraoptic nuclei in the rat.Brain Res Bull.2006 Dec 11;71(1-3):200-7.
5 Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (... J Med Chem. 2005 Apr 21;48(8):3051-9.
6 3-demethoxy-3-glycosylaminothiocolchicines: Synthesis of a new class of putative muscle relaxant compounds. J Med Chem. 2006 Sep 7;49(18):5571-7.
7 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.