General Information of Drug (ID: DMYK31O)

Drug Name
MDL-28170 Drug Info
Synonyms MDL-2170
Indication
Disease Entry ICD 11 Status REF
Alzheimer disease 8A20 Terminated [1]
Cross-matching ID
PubChem CID
72430
ChEBI ID
CHEBI:82818
CAS Number
CAS 88191-84-8
TTD Drug ID
DMYK31O
VARIDT Drug ID
DR00841

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Drug(s) Targeting Calpain-2 (CAPN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ABT-957 DMB9N4J Alzheimer disease 8A20 Phase 1 [3]
PMID25399719-Compound-17 DMRXKJZ N. A. N. A. Patented [4]
Epoxysuccinate derivative 9 DM49FU0 N. A. N. A. Patented [4]
Epoxysuccinate derivative 4 DMCF6M8 N. A. N. A. Patented [4]
Carboxamide derivative 7 DM8TQS4 N. A. N. A. Patented [4]
Epoxysuccinate derivative 7 DMTSPVF N. A. N. A. Patented [4]
Carboxamide derivative 10 DM5WMO9 N. A. N. A. Patented [4]
Carboxamide derivative 11 DM1DN94 N. A. N. A. Patented [4]
Carboxamide derivative 8 DM6HI34 N. A. N. A. Patented [4]
Epoxysuccinate derivative 10 DMYF39U N. A. N. A. Patented [4]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calpain-2 (CAPN2) TTG5QB7 CAN2_HUMAN Inhibitor [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003692)
2 Synthesis of a small library of diketopiperazines as potential inhibitors of calpain. Bioorg Med Chem Lett. 2005 Jun 15;15(12):3034-8.
3 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
4 An updated patent review of calpain inhibitors (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):17-31.