Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM7KJTI)

Drug Name
PD-153035 Drug Info
Synonyms
183322-45-4; PD153035 hydrochloride; N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride; PD153035 HCl; PD 153035 HYDROCHLORIDE; PD-153035 hydrochloride; PD153035 (Hydrochloride); Tyrphostin AG 1517; AG 1517 hydrochloride; SU-5271 hydrochloride; UNII-AHJ252P69N; ZM 252868; SU 5271; AG 1517; 4-[(3-BROMOPHENYL)AMINO]-6,7-DIMETHOXYQUINAZOLINE HYDROCHLORIDE; AHJ252P69N; pd 153035; PD153035.HCl; CHEMBL1204168; 6,7-Dimethoxy-4-[N-(3-bromophenyl)amino]quinazoline hydrochloride; C16H15BrClN3O2; 4-Quinazolinamine, N-(3-bromo
Indication
Disease Entry ICD 11 Status REF
Psoriasis vulgaris EA90 Discontinued in Phase 1 [1]
Cross-matching ID
PubChem CID
4705
ChEBI ID
CHEBI:91076
CAS Number
CAS 153436-54-5
TTD Drug ID
DM7KJTI

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Epidermal growth factor receptor (EGFR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [5]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [6]
Gefitinib DM15F0X Colon adenocarcinoma Approved [7]
Erlotinib DMCMBHA Adrenal gland neoplasm Approved [8]
Vandetanib DMRICNP Solid tumour/cancer 2A00-2F9Z Approved [9]
Dacomitinib DMOH8VY Non-small-cell lung cancer 2C25.Y Approved [10]
BIBW 2992 DMTKD7Q Non-small-cell lung cancer 2C25.Y Approved [11]
SKI-758 DMQ8E9R Ischemia 8B10-8B11 Approved [12]
Epidermal growth factor DMVONE6 Vulnerary ND56.Z Approved [10]
Merimepodib DM0HS92 Breast cancer 2C60-2C65 Approved [13]
BIBW 2992 DMTKD7Q Non-small-cell lung cancer 2C25.Y Approved [22]
Gefitinib DM15F0X Colon adenocarcinoma Approved [23]
Erlotinib DMCMBHA Adrenal gland neoplasm Approved [24]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [25]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [26]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [27]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [28]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [29]
Selenium DM25CGV N. A. N. A. Approved [30]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [31]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Affected By Aromatase (CYP19A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [14]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [15]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [16]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [17]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [16]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
FADROZOLE DM3C5GZ Breast cancer 2C60-2C65 Approved [19]
Bifonazole DM3KN7V Fungal infection 1F29-1F2F Approved [20]
Quercetin DM3NC4M Obesity 5B81 Approved [21]
Fluoxetine DM3PD2C Bipolar depression Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratin, type I cytoskeletal 14 (KRT14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [34]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [35]
Folic Acid DMEMBJC Colorectal carcinoma Approved [36]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [32]
Bexarotene DMOBIKY Cutaneous T-cell lymphoma 2B01 Approved [37]
Methamphetamine DMPM4SK Anxiety Approved [38]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratin, type II cytoskeletal 6A (KRT6A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [39]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [41]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [42]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [32]
Arsenic DMTL2Y1 N. A. N. A. Approved [43]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [44]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratin, type II cytoskeletal 6B (KRT6B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [40]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [45]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [46]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [47]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [48]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [49]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [50]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [51]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Keratin, type II cytoskeletal 1 (KRT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [52]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [32]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [53]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [35]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [54]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [32]
Arsenic DMTL2Y1 N. A. N. A. Approved [55]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [56]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor AP-2-alpha (TFAP2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [57]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [58]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
Panobinostat DM58WKG Chronic graft versus host disease Approved [60]
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [57]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [40]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [62]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [62]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratin, type I cytoskeletal 16 (KRT16)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcipotriol DM03CP7 Psoriasis EA90 Approved [63]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [64]
Testosterone DM7HUNW Hot flushes GA30 Approved [65]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [66]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [68]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [35]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [69]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [71]
Gefitinib DM15F0X Colon adenocarcinoma Approved [72]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [74]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [75]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [76]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [75]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [77]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [78]
Methotrexate DM2TEOL Anterior urethra cancer Approved [79]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Retinoic acid receptor beta (RARB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [80]
Quercetin DM3NC4M Obesity 5B81 Approved [81]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [82]
Panobinostat DM58WKG Chronic graft versus host disease Approved [60]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [68]
Ethanol DMDRQZU Chronic pain MG30 Approved [84]
Folic Acid DMEMBJC Colorectal carcinoma Approved [85]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [86]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Parathyroid hormone-related protein (PTHLH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [87]
Ceruletide DM2WE5K Caerulein stimulated gastric and pancreatic secretion 5A4Y Approved [88]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [91]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [66]
Leflunomide DMR8ONJ Arthritis FA20 Approved [93]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [94]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
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Drug(s) Affected By Keratin, type I cytoskeletal 13 (KRT13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [96]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [97]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [98]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [69]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [99]
Paclitaxel DMLB81S Breast carcinoma Approved [100]
Afimoxifene DMFORDT Breast cancer 2C60-2C65 Phase 2 [101]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [49]
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Drug(s) Affected By Keratin, type II cytoskeletal 5 (KRT5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [32]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [34]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [68]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [35]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [32]
Bexarotene DMOBIKY Cutaneous T-cell lymphoma 2B01 Approved [37]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Trans-acting T-cell-specific transcription factor GATA-3 (GATA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [102]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [103]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Panobinostat DM58WKG Chronic graft versus host disease Approved [60]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [105]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [40]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxisome proliferator-activated receptor gamma (PPARG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [107]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [108]
Quercetin DM3NC4M Obesity 5B81 Approved [109]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [110]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [111]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [112]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [113]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [114]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [115]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [116]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratin, type II cytoskeletal 6C (KRT6C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [35]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [69]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [45]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [117]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [48]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [50]
chloropicrin DMSGBQA Discovery agent N.A. Investigative [118]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Hepatocyte nuclear factor 3-alpha (FOXA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [80]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [17]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [102]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [80]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [119]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [91]
Leflunomide DMR8ONJ Arthritis FA20 Approved [93]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [120]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tripartite motif-containing protein 29 (TRIM29)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [121]
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [40]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [68]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [124]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [35]
Arsenic DMTL2Y1 N. A. N. A. Approved [125]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [126]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor protein 63 (TP63)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [127]
Quercetin DM3NC4M Obesity 5B81 Approved [128]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Panobinostat DM58WKG Chronic graft versus host disease Approved [129]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [40]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [130]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [131]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Topotecan DMP6G8T Central nervous system neoplasm Approved [133]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [134]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Epidermal growth factor receptor (EGFR) TTGKNB4 EGFR_HUMAN Modulator [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Aromatase (CYP19A1) OTZ6XF74 CP19A_HUMAN Gene/Protein Processing [3]
Epidermal growth factor receptor (EGFR) OTAPLO1S EGFR_HUMAN Gene/Protein Processing [4]
Hepatocyte nuclear factor 3-alpha (FOXA1) OTEBY0TD FOXA1_HUMAN Gene/Protein Processing [4]
Keratin, type I cytoskeletal 13 (KRT13) OTTYSKGX K1C13_HUMAN Gene/Protein Processing [4]
Keratin, type I cytoskeletal 14 (KRT14) OTUVZ1DW K1C14_HUMAN Gene/Protein Processing [4]
Keratin, type I cytoskeletal 16 (KRT16) OTGA0EQN K1C16_HUMAN Gene/Protein Processing [4]
Keratin, type II cytoskeletal 1 (KRT1) OTIOJWA4 K2C1_HUMAN Gene/Protein Processing [4]
Keratin, type II cytoskeletal 5 (KRT5) OTVGI9HT K2C5_HUMAN Gene/Protein Processing [4]
Keratin, type II cytoskeletal 6A (KRT6A) OT392M5T K2C6A_HUMAN Gene/Protein Processing [4]
Keratin, type II cytoskeletal 6B (KRT6B) OTBXJYHY K2C6B_HUMAN Gene/Protein Processing [4]

References

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4 Activation of PPAR and inhibition of cell proliferation reduces key proteins associated with the basal subtype of bladder cancer in As3+-transformed UROtsa cells. PLoS One. 2020 Aug 21;15(8):e0237976. doi: 10.1371/journal.pone.0237976. eCollection 2020.
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6 Triple negative breast cancer--current status and prospective targeted treatment based on HER1 (EGFR), TOP2A and C-MYC gene assessment. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2009 Mar;153(1):13-7.
7 Gefitinib ('Iressa', ZD1839) and new epidermal growth factor receptor inhibitors. Br J Cancer. 2004 Feb 9;90(3):566-72.
8 Quantitative prediction of fold resistance for inhibitors of EGFR. Biochemistry. 2009 Sep 8;48(35):8435-48.
9 A comparison of physicochemical property profiles of marketed oral drugs and orally bioavailable anti-cancer protein kinase inhibitors in clinical development. Curr Top Med Chem. 2007;7(14):1408-22.
10 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1797).
11 Boehringer Ingelheim. Product Development Pipeline. June 2 2009.
12 Synthesis and Src kinase inhibitory activity of a series of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-furyl-3-quinolinecarbonitriles. J Med Chem. 2006 Dec 28;49(26):7868-76.
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15 Cannabidiol (CBD) but not tetrahydrocannabinol (THC) dysregulate in vitro decidualization of human endometrial stromal cells by disruption of estrogen signaling. Reprod Toxicol. 2020 Apr;93:75-82. doi: 10.1016/j.reprotox.2020.01.003. Epub 2020 Jan 14.
16 Effects of selective serotonin reuptake inhibitors on three sex steroids in two versions of the aromatase enzyme inhibition assay and in the H295R cell assay. Toxicol In Vitro. 2015 Oct;29(7):1729-35.
17 Arsenite and cadmium promote the development of mammary tumors. Carcinogenesis. 2020 Jul 14;41(7):1005-1014. doi: 10.1093/carcin/bgz176.
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19 Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitors of aldosterone synthase. J Med Chem. 2005 Mar 10;48(5):1563-75.
20 Comparative assessment of the inhibition of recombinant human CYP19 (aromatase) by azoles used in agriculture and as drugs for humans. Endocr Res. 2004 Aug;30(3):387-94.
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22 Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors. J Med Chem. 2011 Mar 10;54(5):1347-55. doi: 10.1021/jm101396q. Epub 2011 Feb 15.
23 Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival. Cancer Res. 2006 Jun 1;66(11):5542-8. doi: 10.1158/0008-5472.CAN-05-4620.
24 Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med. 2004 May 20;350(21):2129-39. doi: 10.1056/NEJMoa040938. Epub 2004 Apr 29.
25 The dual ErbB1/ErbB2 inhibitor, lapatinib (GW572016), cooperates with tamoxifen to inhibit both cell proliferation- and estrogen-dependent gene expression in antiestrogen-resistant breast cancer. Cancer Res. 2005 Jan 1;65(1):18-25.
26 A fine-needle aspirate-based vulnerability assay identifies polo-like kinase 1 as a mediator of gemcitabine resistance in pancreatic cancer. Mol Cancer Ther. 2010 Feb;9(2):311-8. doi: 10.1158/1535-7163.MCT-09-0693. Epub 2010 Jan 26.
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28 Sertraline induces endoplasmic reticulum stress in hepatic cells. Toxicology. 2014 Aug 1;322:78-88. doi: 10.1016/j.tox.2014.05.007. Epub 2014 May 24.
29 Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. PLoS One. 2010 Dec 17;5(12):e14352. doi: 10.1371/journal.pone.0014352.
30 Inhibition of invasion and induction of apoptosis by selenium in human malignant brain tumour cells in vitro. Int J Oncol. 2007 May;30(5):1263-71.
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