General Information of Drug (ID: DMCT2YF)

Drug Name
Emetine Drug Info
Synonyms
Emetine hydrochloride; EMETINE; 14198-59-5; MLS000028478; SMR000058444; NSC-33669; NSC33669; Emetine monohydrochloride; Opera_ID_1460; Cephaeline methyl ether HCl; AC1O7FP4; SCHEMBL636599; CHEMBL513000; DTXSID80424947; MolPort-004-964-890; Cephaeline methyl ether hydrochloride; NSC752340; AKOS024374935; NSC-752340; ST51014995; Emetan,7',10,11-tetramethoxy-, dihydrochloride; Q-100155; 10-[((1R)-6,7-dimethoxy(1,2,3,4-tetrahydroisoquinolyl))methyl](10S,11aS,9R)-9- ethyl-2,3-dimethoxy-5,6,7,11a-tetrahydropiperidino[2,1-a]isoquinolin
Indication
Disease Entry ICD 11 Status REF
Hepatitis virus infection 1E50-1E51 Approved [1]
Cross-matching ID
PubChem CID
10219
ChEBI ID
CHEBI:4781
CAS Number
CAS 483-18-1
TTD Drug ID
DMCT2YF
VARIDT Drug ID
DR00554
INTEDE Drug ID
DR0571

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [7]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [8]
Methotrexate DM2TEOL Anterior urethra cancer Approved [9]
Folic Acid DMEMBJC Colorectal carcinoma Approved [10]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [9]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [9]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [11]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [9]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [12]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [13]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [14]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [15]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [16]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [18]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [19]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [20]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [21]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [15]
Verapamil DMA7PEW Angina pectoris BA40 Approved [22]
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Drug(s) Metabolized By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [23]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [24]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [25]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [18]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [22]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [26]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [27]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [28]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [29]
Propranolol DM79NTF Angina pectoris BA40 Approved [30]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [31]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [33]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [34]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [35]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Folic Acid DMEMBJC Colorectal carcinoma Approved [37]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [38]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [39]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [40]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [41]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [42]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [44]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [45]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [46]
Prednisone DM2HG4X Acute asthma CA23 Approved [47]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [48]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [49]
Methotrexate DM2TEOL Anterior urethra cancer Approved [50]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [51]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [52]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [54]
Panobinostat DM58WKG Chronic graft versus host disease Approved [55]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [56]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [57]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [58]
Menthol DMG2KW7 Back pain ME84.Z Approved [59]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [60]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Selenium DM25CGV N. A. N. A. Approved [62]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [63]
Quercetin DM3NC4M Obesity 5B81 Approved [64]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [65]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [66]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [68]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [69]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [70]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [71]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [72]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [73]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [74]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [75]
Testosterone enanthate DMB6871 N. A. N. A. Approved [76]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [77]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [78]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [39]
Mebendazole DMO14SG Ascariasis 1F62 Approved [5]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [79]
Gefitinib DM15F0X Colon adenocarcinoma Approved [80]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [81]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [82]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [83]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [84]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [83]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [85]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [86]
Methotrexate DM2TEOL Anterior urethra cancer Approved [87]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [88]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [89]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [90]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [52]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [91]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [92]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [95]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [93]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 3 (CCL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [96]
Methotrexate DM2TEOL Anterior urethra cancer Approved [50]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [97]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [98]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [99]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [100]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [101]
Betamethasone DMAHJEF Acute adrenal insufficiency Approved [5]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [96]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [5]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [102]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [103]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [104]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [6]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [105]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [73]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [106]
Leflunomide DMR8ONJ Arthritis FA20 Approved [107]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [75]
Testosterone enanthate DMB6871 N. A. N. A. Approved [76]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 4 (CCL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [97]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [98]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [101]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [109]
Betamethasone DMAHJEF Acute adrenal insufficiency Approved [5]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [110]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [58]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [111]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [5]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [96]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [112]
Gefitinib DM15F0X Colon adenocarcinoma Approved [113]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [114]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [46]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [115]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [116]
Methotrexate DM2TEOL Anterior urethra cancer Approved [50]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [117]
Quercetin DM3NC4M Obesity 5B81 Approved [118]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 5 (CCL5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [119]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [120]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [121]
Methotrexate DM2TEOL Anterior urethra cancer Approved [50]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [122]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [123]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [124]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [101]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [125]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [126]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [112]
Gefitinib DM15F0X Colon adenocarcinoma Approved [127]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [114]
Selenium DM25CGV N. A. N. A. Approved [62]
Pentosan Polysulfate DM2HRKE Interstitial cystitis GC00.3 Approved [128]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [85]
Methotrexate DM2TEOL Anterior urethra cancer Approved [129]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [130]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [131]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [132]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [133]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [135]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [136]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [137]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [138]
Gefitinib DM15F0X Colon adenocarcinoma Approved [139]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [140]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [142]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [133]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [143]
Paclitaxel DMLB81S Breast carcinoma Approved [144]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [145]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [132]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [42]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [146]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [135]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [136]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [3]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
72 kDa type IV collagenase (MMP2) OT5NIWA2 MMP2_HUMAN Gene/Protein Processing [4]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Gene/Protein Processing [5]
C-C motif chemokine 3 (CCL3) OTW2H3ND CCL3_HUMAN Gene/Protein Processing [5]
C-C motif chemokine 4 (CCL4) OT6B8P25 CCL4_HUMAN Gene/Protein Processing [5]
C-C motif chemokine 5 (CCL5) OTSCA5CK CCL5_HUMAN Gene/Protein Processing [5]
Interleukin-6 receptor subunit alpha (IL6R) OTCQL07Z IL6RA_HUMAN Gene/Protein Processing [5]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Gene/Protein Processing [5]
Matrix metalloproteinase-9 (MMP9) OTB2QDAV MMP9_HUMAN Gene/Protein Processing [4]
Microtubule-associated protein tau (MAPT) OTMTP2Z7 TAU_HUMAN Gene/Protein Processing [6]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Post-Translational Modifications [4]

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48 Ciprofloxacin decreases survival in HT-29 cells via the induction of TGF-beta1 secretion and enhances the anti-proliferative effect of 5-fluorouracil. Br J Pharmacol. 2009 Jun;157(3):362-70. doi: 10.1111/j.1476-5381.2009.00161.x. Epub 2009 Apr 9.
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