Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMHPYSM)

Drug Name
Ellipticine Drug Info
Synonyms
ellipticine; 519-23-3; Elliptisine; 5,11-Dimethyl-6H-pyrido[4,3-b]carbazole; NSC 71795; TCMDC-125546; NSC-71795; 5,11-Dimethyl-6H-pyrido(4,3-b)carbazole; ICIG 770; 5,11-Dimethylpyrido[4,3-b]carbazole; CCRIS 2003; CP 5; UNII-117VLW7484; NSC71795; EINECS 208-264-0; CHEMBL123; BRN 0221300; MLS000736786; MLS000028487; CHEBI:4776; 6H-Pyrido(4,3-b)carbazole, 5,11-dimethyl-; CCG-36483; 117VLW7484; SMR000058370; 6H-Pyrido[4,3-b]carbazole,5,11-dimethyl-; 6H-Pyrido[4,3-b]carbazole, 5,11-dimethyl-; SR-01000003083; elliptecine; Ellipticin
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
3213
ChEBI ID
CHEBI:4776
CAS Number
CAS 519-23-3
TTD Drug ID
DMHPYSM

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting DNA topoisomerase II (TOP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [6]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [7]
Teniposide DMLW57T Acute lymphoblastic leukaemia 2A85 Approved [6]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [8]
Idarubicin DMM0XGL Acute myelogenous leukaemia 2A41 Approved [6]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [6]
Lomefloxacin DMVRH9C Bacterial infection 1A00-1C4Z Approved [9]
Dexrazoxane DMD7X1O Breast cancer 2C60-2C65 Approved [6]
Podofilox DMT2EJP Condyloma 1A95 Approved [10]
Enoxacin DMYTE6L Acute gonococcal cervicitis Approved [11]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [12]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [14]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [15]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [16]
Paclitaxel DMLB81S Breast carcinoma Approved [17]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [18]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [19]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [20]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [21]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [22]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [23]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [24]
Gefitinib DM15F0X Colon adenocarcinoma Approved [25]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Etretinate DM2CZFA Keratosis ED56 Approved [28]
Prednisone DM2HG4X Acute asthma CA23 Approved [29]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [30]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [31]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [32]
Gefitinib DM15F0X Colon adenocarcinoma Approved [33]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [34]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [35]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [36]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [30]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [36]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [37]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [38]
Methotrexate DM2TEOL Anterior urethra cancer Approved [39]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [40]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [41]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [42]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [43]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [44]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [32]
Verapamil DMA7PEW Angina pectoris BA40 Approved [45]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [46]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [47]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [48]
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Drug(s) Affected By G2/mitotic-specific cyclin-B1 (CCNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [49]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [50]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [24]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [51]
Selenium DM25CGV N. A. N. A. Approved [52]
Etretinate DM2CZFA Keratosis ED56 Approved [28]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [30]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [53]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [54]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
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Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [57]
Selenium DM25CGV N. A. N. A. Approved [58]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [59]
Etretinate DM2CZFA Keratosis ED56 Approved [60]
Methotrexate DM2TEOL Anterior urethra cancer Approved [61]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [62]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [63]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [64]
Quercetin DM3NC4M Obesity 5B81 Approved [65]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [66]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [67]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [48]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [68]
Gefitinib DM15F0X Colon adenocarcinoma Approved [69]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Selenium DM25CGV N. A. N. A. Approved [58]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [71]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [72]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [73]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [74]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [75]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [47]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [76]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [77]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [78]
Gefitinib DM15F0X Colon adenocarcinoma Approved [79]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [80]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [81]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [82]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [74]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [83]
Paclitaxel DMLB81S Breast carcinoma Approved [84]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [85]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [73]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [44]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [47]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [76]
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Drug(s) Affected By M-phase inducer phosphatase 3 (CDC25C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [49]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [87]
Methotrexate DM2TEOL Anterior urethra cancer Approved [88]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [90]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [91]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [92]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [93]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [94]
Testosterone DM7HUNW Hot flushes GA30 Approved [95]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [96]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [97]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [98]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [16]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [99]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [100]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [101]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [102]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [104]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [105]
Gefitinib DM15F0X Colon adenocarcinoma Approved [69]
Prednisone DM2HG4X Acute asthma CA23 Approved [29]
Methotrexate DM2TEOL Anterior urethra cancer Approved [106]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [107]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [108]
Quercetin DM3NC4M Obesity 5B81 Approved [109]
Fluoxetine DM3PD2C Bipolar depression Approved [110]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [111]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [113]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [114]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [32]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [46]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [115]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [116]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [35]
Meloxicam DM2AR7L Arthritis FA20 Approved [117]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [118]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [119]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [40]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [104]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [32]
Verapamil DMA7PEW Angina pectoris BA40 Approved [45]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [120]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [115]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [87]
Meloxicam DM2AR7L Arthritis FA20 Approved [121]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [30]
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Drug(s) Affected By DNA topoisomerase 2-beta (TOP2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [122]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [123]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [126]
Menthol DMG2KW7 Back pain ME84.Z Approved [127]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [128]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [51]
Arsenic DMTL2Y1 N. A. N. A. Approved [129]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [130]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [131]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [132]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [133]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [134]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [135]
Ethacrynic acid DM60QMR Edema MG29 Approved [136]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [137]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [138]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [139]
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Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [140]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [141]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [142]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [143]
Capsaicin DMGMF6V Back pain ME84.Z Approved [144]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [145]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [146]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [145]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [141]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [44]
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Drug(s) Affected By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [140]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [147]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [145]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [142]
Capsaicin DMGMF6V Back pain ME84.Z Approved [144]
Zafirlukast DMHNQOG Asthma CA23 Approved [148]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [145]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [149]
Fluconazole DMOWZ6B Cryptococcal meningitis Approved [142]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [145]
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Drug(s) Affected By Cytochrome P450 2E1 (CYP2E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fomepizole DM6VOWQ Athylene glycol or methanol poisoning NE61 Approved [150]
Ademetionine DMYQDBO Hepatic fibrosis DB93.0 Approved [151]
Theophylline DMRJFN9 Bronchitis CA20 Approved [44]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [152]
Ethanol DMDRQZU Chronic pain MG30 Approved [153]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [154]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [155]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Didanosine DMI2QPE Human immunodeficiency virus infection 1C62 Approved [44]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [141]
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Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [156]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [156]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [156]
Capsaicin DMGMF6V Back pain ME84.Z Approved [144]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [157]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [146]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [158]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [159]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [160]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [44]
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Drug(s) Affected By E3 ubiquitin-protein ligase Mdm2 (MDM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Flucytosine DM13VTW Cryptococcal meningitis Approved [161]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [161]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [162]
Methotrexate DM2TEOL Anterior urethra cancer Approved [88]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [163]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [14]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [92]
Amifostine DM5FL14 Mucositis CA00 Approved [164]
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Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [165]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [140]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [166]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [142]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [145]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [145]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [167]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [168]
Capsaicin DMGMF6V Back pain ME84.Z Approved [169]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [170]
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Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [131]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [171]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [172]
Estrone DM5T6US Acne vulgaris ED80 Approved [173]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [174]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [175]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [176]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [177]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [178]
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Drug(s) Affected By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [179]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [180]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [181]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [182]
Oxatomide DM1F42Z Hay fever CA08.00 Approved [183]
Cinacalcet DMCX0K3 Hyperparathyroidism 5A51 Approved [184]
Capsaicin DMGMF6V Back pain ME84.Z Approved [144]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [145]
Quinidine DMLPICK N. A. N. A. Approved [185]
Buprenorphine DMPRI8G Opioid dependence 6C43.2Z Approved [186]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNA topoisomerase II (TOP2) TT0IHXV TOP2A_HUMAN; TOP2B_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [2]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [2]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [2]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [2]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [3]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [3]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Gene/Protein Processing [4]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Regulation of Drug Effects [5]
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Regulation of Drug Effects [5]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Regulation of Drug Effects [5]

References

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