Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJAPE7)

Drug Name
Methylene blue Drug Info
Synonyms
methylene blue; 61-73-4; Methylthioninium chloride; Swiss Blue; Chromosmon; Methylene Blue N; Methylenium ceruleum; Urolene blue; Methylene Blue chloride; Solvent blue 8; Bleu de methylene; Methylene Blue G; Methylene Blue A; External Blue 1; Methylene Blue D; Methylene Blue B; Methylene Blue anhydrous; CI Basic Blue 9; Methylene Blue ZF; Methylene Blue SP; Methylene Blue NZ; Methylene Blue BX; Methylene Blue BD; Methylene Blue SG; Tetramethylene Blue; Methylene Blue ZX; Methylene Blue FZ; Methylene Blue BP; Calcozine; 3,7-Bis-dimethylamino-phenothiazin-5-ylium
Indication
Disease Entry ICD 11 Status REF
Acquired methemoglobinemia 3A93 Approved [1]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2 [2]
Cross-matching ID
PubChem CID
6099
ChEBI ID
CHEBI:6872
CAS Number
CAS 61-73-4
TTD Drug ID
DMJAPE7

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Patented Agent(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Monoamine oxidase (MAO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Moclobemide DMNZWL7 Depression 6A70-6A7Z Approved [11]
Phenelzine DMHIDUE Depression 6A70-6A7Z Approved [11]
Tranylcypromine DMGB5RE Major depressive disorder 6A70.3 Approved [11]
Selegiline DM6034S Major depressive disorder 6A70.3 Approved [11]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [11]
Pargyline DMM0HR1 Hypertension BA00-BA04 Approved [11]
Ergoloid mesylate DMORPBA Alzheimer disease 8A20 Approved [12]
Cyclopropylamine derivative 11 DMMJ0YN N. A. N. A. Patented [13]
PMID27019002-Compound-20a DMRX748 N. A. N. A. Patented [13]
Cyclopropylamine derivative 9 DMX7YAL N. A. N. A. Patented [13]
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Drug(s) Targeting Guanylate cyclase (GC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [14]
Isosorbide Dinitrate DMBI4JG Anal fissure DB50.0 Approved [14]
Isosorbide Mononitrate DMYLMU0 Angina pectoris BA40 Approved [14]
Erythrityl Tetranitrate DMFGQ2S Angina pectoris BA40 Approved [14]
Pirsidomine DMHI6GE Angina pectoris BA40 Phase 2 [15]
IW-1701 DM457XO Sickle-cell disorder 3A51 Phase 2 [16]
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Drug(s) Affected By Amine oxidase B (MAOB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [17]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Quercetin DM3NC4M Obesity 5B81 Approved [19]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [20]
Selegiline DM6034S Major depressive disorder 6A70.3 Approved [21]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [22]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [23]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [24]
BENZYL BENZOATE DMDPYI5 Infestations of lice and scabies 1G00.Z Approved [25]
Linezolid DMGFPU2 Bacteremia 1A73 Approved [26]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [27]
Methotrexate DM2TEOL Anterior urethra cancer Approved [28]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [31]
Paclitaxel DMLB81S Breast carcinoma Approved [32]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [33]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [34]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [35]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [36]
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Drug(s) Affected By Microtubule-associated protein tau (MAPT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [37]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [38]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [39]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [9]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [40]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [22]
Leflunomide DMR8ONJ Arthritis FA20 Approved [42]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [23]
Testosterone enanthate DMB6871 N. A. N. A. Approved [43]
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Drug(s) Affected By Glucose-6-phosphate 1-dehydrogenase (G6PD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [44]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [10]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [45]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [46]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [48]
Quercetin DM3NC4M Obesity 5B81 Approved [19]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [50]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [51]
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Drug(s) Affected By Acetylcholinesterase (ACHE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetylcholine DMDF79Z Cataract 9B10 Approved [52]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [53]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [54]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [56]
L-Glutamic Acid DM4PUDW Schizophrenia 6A20 Approved [54]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [57]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [58]
Neostigmine DM6T2J3 Myasthenia gravis 8C6Y Approved [59]
Testosterone DM7HUNW Hot flushes GA30 Approved [60]
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Drug(s) Affected By 6-phosphogluconate dehydrogenase, decarboxylating (PGD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [19]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [61]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [62]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [23]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [24]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Benzoic Acid DMKB9FI Alopecia areata ED70.2 Approved [63]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [65]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [66]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [67]
Fructose DM43AN2 Vomiting MD90 Approved [10]
Ketoprofen DMRKXPT Bursitis Approved [10]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [68]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [69]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [70]
Gefitinib DM15F0X Colon adenocarcinoma Approved [71]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [72]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Guanylate cyclase (GC) TT6HPVC NOUNIPROTAC Inhibitor [3]
Monoamine oxidase (MAO) TT32XQJ NOUNIPROTAC Not Available [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
6-phosphogluconate dehydrogenase, decarboxylating (PGD) OTVG296F 6PGD_HUMAN Gene/Protein Processing [5]
Acetylcholinesterase (ACHE) OT2H8HG6 ACES_HUMAN Gene/Protein Processing [6]
Amine oxidase B (MAOB) OTTDFM1O AOFB_HUMAN Gene/Protein Processing [7]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [8]
Glucose-6-phosphate 1-dehydrogenase (G6PD) OT300SMK G6PD_HUMAN Gene/Protein Processing [5]
Microtubule-associated protein tau (MAPT) OTMTP2Z7 TAU_HUMAN Gene/Protein Processing [9]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Drug Response [10]

References

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