Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPU2WX)

Drug Name
Omacetaxine mepesuccinate Drug Info
Synonyms Synribo (TN)
Indication
Disease Entry ICD 11 Status REF
Adult acute monocytic leukemia Approved [1]
Chronic myelogenous leukaemia 2A20.0 Approved [1]
Chronic myeloid leukaemia 2A20 Approved [2]
Leukemia Approved [1]
Cross-matching ID
PubChem CID
285033
ChEBI ID
CHEBI:71019
CAS Number
CAS 26833-87-4
TTD Drug ID
DMPU2WX
ACDINA Drug ID
D01298

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Ribosome A (hRA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arbekacin DMHTXSL Bacterial infection 1A00-1C4Z Approved [7]
Drug(s) Affected By Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHUK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [8]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [9]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [11]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [13]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [15]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [16]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [17]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [18]
Methotrexate DM2TEOL Anterior urethra cancer Approved [19]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [20]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [21]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [22]
Paclitaxel DMLB81S Breast carcinoma Approved [23]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [24]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [25]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [26]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [27]
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Drug(s) Affected By Cyclin-dependent kinase 1 (CDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [28]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [29]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [30]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [31]
Selenium DM25CGV N. A. N. A. Approved [32]
Etretinate DM2CZFA Keratosis ED56 Approved [33]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [34]
Methotrexate DM2TEOL Anterior urethra cancer Approved [35]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [36]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [38]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [40]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [41]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [42]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Verapamil DMA7PEW Angina pectoris BA40 Approved [44]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [45]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [46]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [47]
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Drug(s) Affected By G2/mitotic-specific cyclin-B1 (CCNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [28]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [29]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [48]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [31]
Selenium DM25CGV N. A. N. A. Approved [32]
Etretinate DM2CZFA Keratosis ED56 Approved [33]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [49]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [50]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [51]
Methotrexate DM2TEOL Anterior urethra cancer Approved [52]
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Drug(s) Affected By Cyclin-A2 (CCNA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [53]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [29]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [54]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [55]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [56]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [57]
Methotrexate DM2TEOL Anterior urethra cancer Approved [52]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [36]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [58]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
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Drug(s) Affected By G1/S-specific cyclin-E1 (CCNE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [59]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [56]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [49]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [57]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Fluoxetine DM3PD2C Bipolar depression Approved [60]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [61]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [62]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [63]
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Drug(s) Affected By Cyclin-dependent kinase 2 (CDK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [28]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [29]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [59]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [64]
Selenium DM25CGV N. A. N. A. Approved [32]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [49]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [65]
Methotrexate DM2TEOL Anterior urethra cancer Approved [66]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [67]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [68]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [69]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [70]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [46]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [71]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [72]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [73]
Gefitinib DM15F0X Colon adenocarcinoma Approved [74]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [75]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [76]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [77]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [69]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [78]
Paclitaxel DMLB81S Breast carcinoma Approved [79]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [80]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [68]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [42]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [81]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [46]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [71]
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Drug(s) Affected By Hematopoietic progenitor cell antigen CD34 (CD34)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [82]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [83]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [4]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [84]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Valsartan DMREUQ6 Chronic heart failure BD1Z Approved [86]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [87]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [88]
Napabucasin DMDZ6Q3 Colorectal cancer 2B91.Z Phase 3 [89]
Fenretinide DMRD5SP Macular degeneration 9B78.3 Phase 3 [90]
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Drug(s) Affected By ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [91]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [92]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [4]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [93]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [94]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [95]
Bortezomib DMNO38U Leukemia Approved [96]
Novobiocin DMRFWGK Bacterial infection 1A00-1C4Z Approved [97]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [98]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [99]
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Drug(s) Affected By RAC-alpha serine/threonine-protein kinase (AKT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [100]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [101]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [25]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [47]
Gefitinib DM15F0X Colon adenocarcinoma Approved [102]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [103]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [104]
Selenium DM25CGV N. A. N. A. Approved [105]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [106]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [107]
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Drug(s) Affected By Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [81]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [31]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [109]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [110]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [111]
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [112]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [113]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [114]
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Drug(s) Affected By Serine/threonine-protein kinase mTOR (MTOR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [115]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [8]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [116]
Gefitinib DM15F0X Colon adenocarcinoma Approved [117]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [118]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [107]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [119]
Quercetin DM3NC4M Obesity 5B81 Approved [120]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [121]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [122]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [123]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [124]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [125]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [22]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [126]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [127]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [128]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [129]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [130]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [131]
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Drug(s) Affected By Proliferation marker protein Ki-67 (MKI67)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [132]
Methotrexate DM2TEOL Anterior urethra cancer Approved [52]
Quercetin DM3NC4M Obesity 5B81 Approved [133]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [134]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [135]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [136]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [137]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [138]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [139]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [13]
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Drug(s) Affected By Neurogenic locus notch homolog protein 1 (NOTCH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [142]
Propranolol DM79NTF Angina pectoris BA40 Approved [143]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [114]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [145]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [146]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [147]
Mebendazole DMO14SG Ascariasis 1F62 Approved [148]
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Drug(s) Affected By Ephrin type-B receptor 4 (EPHB4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [149]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [15]
Testosterone enanthate DMB6871 N. A. N. A. Approved [150]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [151]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [147]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [152]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [98]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [153]
Arsenic DMTL2Y1 N. A. N. A. Approved [154]
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Drug(s) Affected By Caspase-7 (CASP7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [155]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [156]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [157]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [158]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [159]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [159]
Methotrexate DM2TEOL Anterior urethra cancer Approved [35]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [160]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [161]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [162]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [163]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [164]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [45]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [165]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [166]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [167]
Meloxicam DM2AR7L Arthritis FA20 Approved [168]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [169]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [170]
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Drug(s) Affected By Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [25]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [171]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [172]
Methotrexate DM2TEOL Anterior urethra cancer Approved [19]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [173]
Quercetin DM3NC4M Obesity 5B81 Approved [174]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [175]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [176]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [177]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
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Drug(s) Affected By Nuclear factor NF-kappa-B p100 subunit (NFKB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [81]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [156]
Methotrexate DM2TEOL Anterior urethra cancer Approved [35]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [121]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [179]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [181]
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Drug(s) Affected By Transcription factor RelB (RELB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [53]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [156]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [31]
Methotrexate DM2TEOL Anterior urethra cancer Approved [19]
Quercetin DM3NC4M Obesity 5B81 Approved [182]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [183]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [109]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [184]
Testosterone DM7HUNW Hot flushes GA30 Approved [185]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [185]
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Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [81]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [47]
Selenium DM25CGV N. A. N. A. Approved [105]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [34]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [186]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [187]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [188]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [91]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [189]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [38]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [131]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Verapamil DMA7PEW Angina pectoris BA40 Approved [44]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [190]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [165]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [191]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Meloxicam DM2AR7L Arthritis FA20 Approved [193]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [49]
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Drug(s) Affected By Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [46]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [190]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [194]
Methotrexate DM2TEOL Anterior urethra cancer Approved [66]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [149]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [196]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [190]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [197]
Ethacrynic acid DM60QMR Edema MG29 Approved [198]
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Drug(s) Affected By Jouberin (AHI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [199]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [114]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [199]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [98]
Arsenic DMTL2Y1 N. A. N. A. Approved [154]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [87]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [199]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [200]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bcl2-associated agonist of cell death (BAD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [201]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [131]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [81]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [202]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [203]
Quercetin DM3NC4M Obesity 5B81 Approved [204]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [205]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [206]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [207]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ribosome A (hRA) TTA4FIU NOUNIPROTAC Modulator [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38) OTG0TTX7 CD38_HUMAN Gene/Protein Processing [4]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [5]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [6]
Bcl2-associated agonist of cell death (BAD) OT63ERYM BAD_HUMAN Gene/Protein Processing [5]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Protein Interaction/Cellular Processes [5]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Protein Interaction/Cellular Processes [5]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Protein Interaction/Cellular Processes [5]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [4]
Cyclin-A2 (CCNA2) OTPHHYZJ CCNA2_HUMAN Gene/Protein Processing [5]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Gene/Protein Processing [5]

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