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Dopaminergic pathway polymorphisms and heroin addiction: further support for association of CSNK1E variants.Pharmacogenomics. 2014 Dec;15(16):2001-9. doi: 10.2217/pgs.14.145.
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Functional polymorphisms of the glutamate receptor N-methyl D-aspartate 2A gene are associated with heroin addiction.Genet Mol Res. 2014 Oct 27;13(4):8714-21. doi: 10.4238/2014.October.27.12.
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GABRB2 Haplotype Association with Heroin Dependence in Chinese Population.PLoS One. 2015 Nov 12;10(11):e0142049. doi: 10.1371/journal.pone.0142049. eCollection 2015.
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A cis-eQTL in OPRM1 is Associated with Subjective Response to Alcohol and Alcohol Use.Alcohol Clin Exp Res. 2017 May;41(5):929-938. doi: 10.1111/acer.13369. Epub 2017 Apr 10.
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OPRD1 gene affects disease vulnerability and environmental stress in patients with heroin dependence in Han Chinese.Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:109-116. doi: 10.1016/j.pnpbp.2018.08.028. Epub 2018 Aug 30.
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Increased mesolimbic GABA concentration blocks heroin self-administration in the rat.J Pharmacol Exp Ther. 2000 Aug;294(2):613-9.
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Adipocyte-derived hormones in heroin addicts: the influence of methadone maintenance treatment. Physiol Res. 2005;54(1):73-78. doi: 10.33549/physiolres.930568.
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High-Frequency Stimulation of the Subthalamic Nucleus Blocks Compulsive-Like Re-Escalation of Heroin Taking in Rats.Neuropsychopharmacology. 2017 Aug;42(9):1850-1859. doi: 10.1038/npp.2016.270. Epub 2016 Dec 5.
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Genome-Wide Association of Heroin Dependence in Han Chinese.PLoS One. 2016 Dec 9;11(12):e0167388. doi: 10.1371/journal.pone.0167388. eCollection 2016.
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Association between stress pathway gene (CRHR1CRHBP) polymorphisms and heroin dependence.J Clin Neurosci. 2018 Aug;54:33-38. doi: 10.1016/j.jocn.2018.05.009. Epub 2018 May 28.
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Effect of Sirtuin-1 on Synaptic Plasticity in Nucleus Accumbens in a Rat Model of Heroin Addiction.Med Sci Monit. 2018 Jun 5;24:3789-3803. doi: 10.12659/MSM.910550.
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Significant association of DRD2 enhancer variant rs12364283 with heroin addiction in a Pakistani population.Ann Hum Genet. 2019 Sep;83(5):367-372. doi: 10.1111/ahg.12322. Epub 2019 Apr 26.
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Changes in Expression of Dopamine, Its Receptor, and Transporter in Nucleus Accumbens of Heroin-Addicted Rats with Brain-Derived Neurotrophic Factor (BDNF) Overexpression.Med Sci Monit. 2017 Jun 9;23:2805-2815. doi: 10.12659/msm.904670.
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Drug addiction and stress-response genetic variability: association study in African Americans.Ann Hum Genet. 2014 Jul;78(4):290-8. doi: 10.1111/ahg.12064. Epub 2014 Apr 26.
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The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence.Biol Psychiatry. 2010 Jan 1;67(1):20-7. doi: 10.1016/j.biopsych.2009.08.019.
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Stress-related genes and heroin addiction: a role for a functional FKBP5 haplotype.Psychoneuroendocrinology. 2014 Jul;45:67-76. doi: 10.1016/j.psyneuen.2014.03.017. Epub 2014 Apr 6.
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GRK5 Is Associated with the Regulation of Methadone Dosage in Heroin Dependence.Int J Neuropsychopharmacol. 2018 Oct 1;21(10):910-917. doi: 10.1093/ijnp/pyy066.
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N-acetylaspartylglutamate Inhibits Heroin Self-Administration and Heroin-Seeking Behaviors Induced by Cue or Priming in Rats.Neurosci Bull. 2017 Aug;33(4):396-404. doi: 10.1007/s12264-017-0140-3. Epub 2017 May 22.
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Polymorphisms in the 5-hydroxytryptamine receptor 3B gene are associated with heroin dependence in the Chinese Han population.Neurosci Lett. 2016 Dec 2;635:123-129. doi: 10.1016/j.neulet.2016.10.033. Epub 2016 Oct 20.
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Association of polymorphisms in the melanocortin receptor type 2 (MC2R, ACTH receptor) gene with heroin addiction.Neurosci Lett. 2008 Apr 25;435(3):234-9. doi: 10.1016/j.neulet.2008.02.042. Epub 2008 Feb 26.
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Genetic polymorphisms of FADS1, FADS2, and FADS3 and fatty acid profiles in subjects received methadone maintenance therapy. Prostaglandins Leukot Essent Fatty Acids. 2018 Sep;136:117-121.
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Expression of brain-derived neurotrophic factors, neurotrophin-3, and neurotrophin-4 in the nucleus accumbens during heroin dependency and withdrawal.Neuroreport. 2017 Aug 2;28(11):654-660. doi: 10.1097/WNR.0000000000000810.
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Contribution of Genetic Polymorphisms and Haplotypes in DRD2, BDNF, and Opioid Receptors to Heroin Dependence and Endophenotypes Among the Han Chinese.OMICS. 2017 Jul;21(7):404-412. doi: 10.1089/omi.2017.0057.
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TPH2 and TPH1: association of variants and interactions with heroin addiction.Behav Genet. 2008 Mar;38(2):133-50. doi: 10.1007/s10519-007-9187-7. Epub 2008 Jan 8.
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Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence.Mol Psychiatry. 2011 Nov;16(11):1139-46. doi: 10.1038/mp.2010.94. Epub 2010 Sep 14.
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Identification of novel risk loci with shared effects on alcoholism, heroin, and methamphetamine dependence.Mol Psychiatry. 2021 Apr;26(4):1152-1161. doi: 10.1038/s41380-019-0497-y. Epub 2019 Aug 28.
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Synaptic Plasticity and Signal Transduction Gene Polymorphisms and Vulnerability to Drug Addictions in Populations of European or African Ancestry.CNS Neurosci Ther. 2015 Nov;21(11):898-904. doi: 10.1111/cns.12450. Epub 2015 Sep 19.
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The evidence for the contribution of the autism susceptibility candidate 2 (AUTS2) gene in heroin dependence susceptibility.J Mol Neurosci. 2014 Dec;54(4):811-9. doi: 10.1007/s12031-014-0421-5. Epub 2014 Nov 15.
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Genetic signatures of heroin addiction.Medicine (Baltimore). 2016 Aug;95(31):e4473. doi: 10.1097/MD.0000000000004473.
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Association analysis of GABRB3 promoter variants with heroin dependence.PLoS One. 2014 Jul 15;9(7):e102227. doi: 10.1371/journal.pone.0102227. eCollection 2014.
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Association between genetic variations of NMDA receptor NR3 subfamily genes and heroin addiction in male Han Chinese.Neurosci Lett. 2016 Sep 19;631:122-125. doi: 10.1016/j.neulet.2016.08.025. Epub 2016 Aug 16.
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A heroin addiction severity-associated intronic single nucleotide polymorphism modulates alternative pre-mRNA splicing of the opioid receptor gene OPRM1 via hnRNPH interactions.J Neurosci. 2014 Aug 13;34(33):11048-66. doi: 10.1523/JNEUROSCI.3986-13.2014.
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Weighted gene co-expression network analysis to explore the mechanism of heroin addiction in human nucleus accumbens.J Cell Biochem. 2020 Feb;121(2):1870-1879. doi: 10.1002/jcb.29422. Epub 2019 Nov 6.
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Genetic association analyses and meta-analysis of Dynorphin-Kappa Opioid system potential functional variants with heroin dependence.Neurosci Lett. 2018 Oct 15;685:75-82. doi: 10.1016/j.neulet.2018.08.023. Epub 2018 Aug 20.
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Proenkephalin mediates the enduring effects of adolescent cannabis exposure associated with adult opiate vulnerability.Biol Psychiatry. 2012 Nov 15;72(10):803-10. doi: 10.1016/j.biopsych.2012.04.026. Epub 2012 Jun 8.
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Evidence for the contribution of genetic variations in regulator of G protein signaling 9 to the genetic susceptibility of heroin dependence.Mol Med Rep. 2015 May;11(5):3908-13. doi: 10.3892/mmr.2015.3210. Epub 2015 Jan 16.
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