Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM54OKX)

Drug Name
Thenoyltrifluoroacetone Drug Info
Synonyms thenoyl trifluoro acetone; MolPort-001-660-116; STK312921; AKOS005437067; ST45092067; (2E)-1,1,1-trifluoro-4-oxo-4-(thiophen-2-yl)but-2-en-2-olate
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5601
CAS Number
CAS 326-91-0
TTD Drug ID
DM54OKX

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Liver carboxylesterase (CES1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [5]
PACTIMIBE DM0NZDT Arteriosclerosis BD40 Phase 2/3 [6]
K-604 DMQVN6P Arteriosclerosis BD40 Phase 2 [7]
Eldacimibe DML7WP0 Hyperlipidaemia 5C80 Phase 2 [8]
GR148672X DM7W6YN Acute lymphoblastic leukaemia 2A85 Clinical trial [9]
Avasimibe DMFG4OM Peripheral vascular disease BD4Z Discontinued in Phase 3 [10]
E-5324 DM562BM Hyperlipidaemia 5C80 Discontinued in Phase 2 [11]
RP-64477 DMTQ3BS Hyperlipidaemia 5C80 Discontinued in Phase 2 [12]
CI-976 DMBO28J Hyperlipidaemia 5C80 Discontinued in Phase 2 [13]
CL-283796 DM7LIDT Hyperlipidaemia 5C80 Discontinued in Phase 2 [14]
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Drug(s) Affected By Leptin (LEP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [15]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [16]
Ramipril DM2R68E Acute heart failure BD10-BD13 Approved [17]
Quercetin DM3NC4M Obesity 5B81 Approved [18]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [19]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [15]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [15]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [20]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [21]
Amlodipine DMBDAZV Angina pectoris BA40 Approved [22]
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Drug(s) Affected By Beclin-1 (BECN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcipotriol DM03CP7 Psoriasis EA90 Approved [23]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [24]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [25]
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Fluoxetine DM3PD2C Bipolar depression Approved [28]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [31]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [32]
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Drug(s) Affected By Autophagy protein 5 (ATG5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [33]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [34]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [35]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [36]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [31]
Promethazine DM6I5GR Hyperemesis gravidarum Approved [37]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [38]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [40]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [41]
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Drug(s) Affected By Superoxide dismutase , mitochondrial (SOD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
Selenium DM25CGV N. A. N. A. Approved [43]
Methotrexate DM2TEOL Anterior urethra cancer Approved [44]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [45]
Epinephrine DM3KJBC Acute asthma CA23 Approved [46]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [48]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [49]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [50]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Liver carboxylesterase (CES1) TTMF541 EST1_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Autophagy protein 5 (ATG5) OT4T5SMS ATG5_HUMAN Drug Response [2]
Beclin-1 (BECN1) OT4X293M BECN1_HUMAN Gene/Protein Processing [2]
Leptin (LEP) OT5Q7ODW LEP_HUMAN Protein Interaction/Cellular Processes [3]
Serine/threonine-protein kinase ULK1 OTXNP0N5 ULK1_HUMAN Gene/Protein Processing [4]
Superoxide dismutase , mitochondrial (SOD2) OTIWXGZ9 SODM_HUMAN Drug Response [2]

References

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