Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMCMOS8)

Drug Name
L-cysteine Drug Info
Synonyms
52-90-4; Cystein; Half-cystine; (R)-Cysteine; Thioserine; (R)-2-Amino-3-mercaptopropanoic acid; L-(+)-Cysteine; L-Cystein; (2R)-2-amino-3-sulfanylpropanoic acid; beta-Mercaptoalanine; Half cystine; FREE CYSTEINE; Cysteine, L-; L-Cys; L-Alanine, 3-mercapto-; L-Zystein; H-Cys-OH; Cisteinum [Latin]; L-2-Amino-3-mercaptopropionic acid; Cisteina [Spanish]; cisteina; Polycysteine; Cysteinum; Cisteinum; (R)-2-Amino-3-mercaptopropionic acid; L Cysteine; alpha-Amino-beta-thiolpropionic acid; L-2-Amino-3-mercaptopropanoic a
Indication
Disease Entry ICD 11 Status REF
Amyloidosis 5D00 Approved [1]
Bronchiectasis CA24 Approved [2]
Bronchitis CA20 Approved [3]
Paracetamol poisoning Approved [4]
Non-small-cell lung cancer 2C25.Y Clinical trial [5]
Cross-matching ID
PubChem CID
5862
ChEBI ID
CHEBI:17561
CAS Number
CAS 52-90-4
TTD Drug ID
DMCMOS8
INTEDE Drug ID
DR2105

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Affected By Retinoblastoma-associated protein (RB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [10]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [11]
Gefitinib DM15F0X Colon adenocarcinoma Approved [12]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [13]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [14]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [15]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [16]
Methotrexate DM2TEOL Anterior urethra cancer Approved [17]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [18]
Quercetin DM3NC4M Obesity 5B81 Approved [19]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [20]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [21]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [22]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [23]
Gefitinib DM15F0X Colon adenocarcinoma Approved [24]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [13]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [25]
Selenium DM25CGV N. A. N. A. Approved [26]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [27]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [28]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [11]
Gefitinib DM15F0X Colon adenocarcinoma Approved [24]
Prednisone DM2HG4X Acute asthma CA23 Approved [29]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [31]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [32]
Quercetin DM3NC4M Obesity 5B81 Approved [33]
Fluoxetine DM3PD2C Bipolar depression Approved [34]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [35]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [36]
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Drug(s) Affected By Arsenite methyltransferase (AS3MT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [37]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [38]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [39]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [43]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [44]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [45]
Ademetionine DMYQDBO Hepatic fibrosis DB93.0 Approved [40]
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Drug(s) Affected By Amino acid transporter heavy chain SLC3A1 (SLC3A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [46]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [48]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [49]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [50]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [51]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [51]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [52]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [53]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [54]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Glutamate-cysteine ligase catalytic (GCLC) DESYL1F GSH1_HUMAN Substrate [6]
Glutamate-cysteine ligase regulatory (GCLM) DEEBDFT GSH0_HUMAN Substrate [6]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Amino acid transporter heavy chain SLC3A1 (SLC3A1) OT56V01A SLC31_HUMAN Regulation of Drug Effects [7]
Arsenite methyltransferase (AS3MT) OTNLWD0N AS3MT_HUMAN Post-Translational Modifications [8]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Gene/Protein Processing [9]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Gene/Protein Processing [9]
Retinoblastoma-associated protein (RB1) OTQJUJMZ RB_HUMAN Post-Translational Modifications [9]

References

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