General Information of Drug (ID: DMUY35B)

Drug Name
Progesterone
Synonyms
progesterone; 57-83-0; Agolutin; Pregn-4-ene-3,20-dione; Luteohormone; Crinone; 4-Pregnene-3,20-dione; Utrogestan; Syngesterone; Progestin; Luteol; Corpus luteum hormone; Progesterol; Progesteronum; Pregnenedione; Glanducorpin; Prometrium; Corlutin; Cyclogest; Progestron; Gestormone; Progestone; Gestone; Progestasert; Progestronol; Methylpregnone; Hormoflaveine; Syngestrets; Proluton; Progekan; Nalutron; Lutoform; Gynlutin; Gesterol; Fologenon; Corporin; Corlutina; Syntolutan; Prolidon; Membrettes; Lutocyclin; Luteodyn; Lucorteum; Corluvite; LPCN-1107; Progesterone (oral, preterm labor); Progesterone (oral, preterm labor), Lipocine
Indication
Disease Entry ICD 11 Status REF
Premature labour JB00 Approved [1], [2]
Contraception QA21 Phase 3 [3]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 314.5
Topological Polar Surface Area (xlogp) 3.9
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 2
ADMET Property
BDDCS Class
Biopharmaceutics Drug Disposition Classification System (BDDCS) Class 2: low solubility and high permeability [4]
Elimination
0% of drug is excreted from urine in the unchanged form [4]
MRTD
The Maximum Recommended Therapeutic Dose (MRTD) of drug that ensured maximising efficacy and moderate side effect is 21.19955 micromolar/kg/day [5]
Water Solubility
The ability of drug to dissolve in water is measured as 0.007 mg/mL [4]
Chemical Identifiers
Formula
C21H30O2
IUPAC Name
(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Canonical SMILES
CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
InChI
InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
InChIKey
RJKFOVLPORLFTN-LEKSSAKUSA-N
Cross-matching ID
PubChem CID
5994
ChEBI ID
CHEBI:17026
CAS Number
57-83-0
DrugBank ID
DB00396
TTD ID
D07BSQ
VARIDT ID
DR00281
INTEDE ID
DR1346
ACDINA ID
D00560

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Progesterone receptor (PGR) TTUV8G9 PRGR_HUMAN Agonist [6]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [7]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [8]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [9]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Substrate [10]
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Substrate [11]
Cytochrome P450 1A1 (CYP1A1) DE6OQ3W CP1A1_HUMAN Substrate [12]
Glutathione S-transferase alpha-1 (GSTA1) DE4ZHS1 GSTA1_HUMAN Substrate [13]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [11]
Cytochrome P450 2A6 (CYP2A6) DEJVYAZ CP2A6_HUMAN Substrate [14]
Cytochrome P450 3A5 (CYP3A5) DEIBDNY CP3A5_HUMAN Substrate [15]
Cytochrome P450 1B1 (CYP1B1) DE9QHP6 CP1B1_HUMAN Substrate [16]
Cytochrome P450 3A7 (CYP3A7) DERD86B CP3A7_HUMAN Substrate [17]
Sulfotransferase 1A1 (SULT1A1) DEYWLRK ST1A1_HUMAN Substrate [18]
Cytochrome P450 4B1 (CYP4B1) DEMF740 CP4B1_HUMAN Substrate [19]
Cholesterol 24-hydroxylase (CYP46A1) DEKP5HX CP46A_HUMAN Substrate [20]
Aldo-keto reductase 1C1 (AKR1C1) DE7P2FB AK1C1_HUMAN Substrate [21]
Steroid 21-hydroxylase (CYP21A2) DE0JMZ5 CP21A_HUMAN Substrate [22]
Cytochrome P450 MEG (cyp106) DEZ1H4L CPXM_BACME Substrate [23]
Cytochrome P450 21A2 (cyp21) DEBY951 A0A250VKS1_STROL Substrate [24], [25]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Premature labour
ICD Disease Classification JB00
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Progesterone receptor (PGR) DTT PGR 3.26E-38 -3.79 -2.5
P-glycoprotein 1 (ABCB1) DTP P-GP 7.04E-04 -2.76E-01 -4.63E-01
Breast cancer resistance protein (ABCG2) DTP BCRP 3.03E-24 -1.50E+00 -1.59E+00
Sulfotransferase 1A1 (SULT1A1) DME SULT1A1 1.61E-03 -2.57E-01 -3.75E-01
Cytochrome P450 4B1 (CYP4B1) DME CYP4B1 6.27E-03 -5.51E-01 -3.60E-01
Cholesterol 24-hydroxylase (CYP46A1) DME CYP46A1 3.65E-26 -7.77E-01 -1.26E+00
Cytochrome P450 2A6 (CYP2A6) DME CYP2A6 4.55E-04 -1.16E-01 -4.21E-01
Cytochrome P450 3A5 (CYP3A5) DME CYP3A5 5.32E-01 2.09E-01 1.24E-01
Mephenytoin 4-hydroxylase (CYP2C19) DME CYP2C19 1.07E-03 -2.00E-01 -3.54E-01
Cytochrome P450 2D6 (CYP2D6) DME CYP2D6 3.27E-02 -6.33E-02 -2.52E-01
Cytochrome P450 1B1 (CYP1B1) DME CYP1B1 2.78E-13 -1.51E+00 -1.15E+00
Aldo-keto reductase 1C1 (AKR1C1) DME AKR1C1 2.01E-05 2.14E-01 3.73E-01
Cytochrome P450 1A1 (CYP1A1) DME CYP1A1 2.46E-01 -7.08E-03 -2.10E-02
Cytochrome P450 2C9 (CYP2C9) DME CYP2C9 4.46E-05 -2.53E-01 -2.36E-01
Glutathione S-transferase alpha-1 (GSTA1) DME GSTA1 4.62E-01 -5.05E-02 -1.52E-01
Cytochrome P450 3A4 (CYP3A4) DME CYP3A4 2.20E-02 -1.08E-01 -2.31E-01
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Drug-Drug Interaction (DDI) Information of This Drug

Coadministration of a Drug Treating the Disease Different from Progesterone (Comorbidity)
DDI Drug Name DDI Drug ID Severity Mechanism Comorbidity REF
Ivosidenib DM8S6T7 Moderate Increased metabolism of Progesterone caused by Ivosidenib mediated induction of CYP450 enzyme. Acute myeloid leukaemia [2A60] [136]
Idarubicin DMM0XGL Moderate Decreased clearance of Progesterone due to the transporter inhibition by Idarubicin. Acute myeloid leukaemia [2A60] [137]
Daunorubicin DMQUSBT Moderate Decreased clearance of Progesterone due to the transporter inhibition by Daunorubicin. Acute myeloid leukaemia [2A60] [137]
Arn-509 DMT81LZ Moderate Increased metabolism of Progesterone caused by Arn-509 mediated induction of CYP450 enzyme. Acute myeloid leukaemia [2A60] [136]
Mitotane DMU1GX0 Moderate Increased metabolism of Progesterone caused by Mitotane mediated induction of CYP450 enzyme. Adrenal cancer [2D11] [136]
Dronedarone DMA8FS5 Moderate Decreased metabolism of Progesterone caused by Dronedarone mediated inhibition of CYP450 enzyme. Angina pectoris [BA40] [138]
Methylphenobarbital DMDSWAG Moderate Increased metabolism of Progesterone caused by Methylphenobarbital mediated induction of CYP450 enzyme. Anxiety disorder [6B00-6B0Z] [139]
Voriconazole DMAOL2S Moderate Decreased metabolism of Progesterone caused by Voriconazole mediated inhibition of CYP450 enzyme. Aspergillosis [1F20] [140]
Posaconazole DMUL5EW Moderate Decreased metabolism of Progesterone caused by Posaconazole mediated inhibition of CYP450 enzyme. Aspergillosis [1F20] [140]
Dalfopristin DM4LTKV Moderate Decreased metabolism of Progesterone caused by Dalfopristin mediated inhibition of CYP450 enzyme. Bacterial infection [1A00-1C4Z] [141]
Clarithromycin DM4M1SG Moderate Decreased metabolism of Progesterone caused by Clarithromycin mediated inhibition of CYP450 enzyme. Bacterial infection [1A00-1C4Z] [142]
Telithromycin DMZ4P3A Moderate Decreased metabolism of Progesterone caused by Telithromycin mediated inhibition of CYP450 enzyme. Bacterial infection [1A00-1C4Z] [143]
Pexidartinib DMS2J0Z Moderate Increased metabolism of Progesterone caused by Pexidartinib mediated induction of CYP450 enzyme. Bone/articular cartilage neoplasm [2F7B] [136]
Lapatinib DM3BH1Y Moderate Decreased metabolism of Progesterone caused by Lapatinib mediated inhibition of CYP450 enzyme. Breast cancer [2C60-2C6Y] [144]
Atorvastatin DMF28YC Minor Decreased metabolism of Progesterone caused by Atorvastatin mediated inhibition of CYP450 enzyme. Cardiovascular disease [BA00-BE2Z] [145]
Secobarbital DM14RF5 Moderate Increased metabolism of Progesterone caused by Secobarbital mediated induction of CYP450 enzyme. Chronic insomnia [7A00] [136]
Phenylbutazone DMAYL0T Moderate Increased metabolism of Progesterone caused by Phenylbutazone mediated induction of CYP450 enzyme. Chronic pain [MG30] [136]
Fidaxomicin DMFP6MV Minor Decreased clearance of Progesterone due to the transporter inhibition by Fidaxomicin. Clostridium difficile enterocolitis [1A04] [142]
Mifepristone DMGZQEF Moderate Decreased metabolism of Progesterone caused by Mifepristone mediated inhibition of CYP450 enzyme. Cushing syndrome [5A70] [142]
Lumacaftor DMCLWDJ Moderate Increased metabolism of Progesterone caused by Lumacaftor mediated induction of CYP450 enzyme. Cystic fibrosis [CA25] [139]
MK-8228 DMOB58Q Moderate Decreased metabolism of Progesterone caused by MK-8228 mediated inhibition of CYP450 enzyme. Cytomegaloviral disease [1D82] [142]
Aprepitant DM053KT Moderate Decreased metabolism of Progesterone caused by Aprepitant mediated inhibition of CYP450 enzyme. Depression [6A70-6A7Z] [146]
Nefazodone DM4ZS8M Moderate Decreased metabolism of Progesterone caused by Nefazodone mediated inhibition of CYP450 enzyme. Depression [6A70-6A7Z] [147]
Griseofulvin DMK54YG Moderate Increased metabolism of Progesterone caused by Griseofulvin mediated induction of CYP450 enzyme. Dermatophytosis [1F28] [136]
Primidone DM0WX6I Moderate Increased metabolism of Progesterone caused by Primidone mediated induction of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [136]
Felbamate DM1V5ZS Moderate Increased metabolism of Progesterone caused by Felbamate mediated induction of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [136]
Oxcarbazepine DM5PU6O Moderate Increased metabolism of Progesterone caused by Oxcarbazepine mediated induction of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [136]
Cenobamate DMGOVHA Moderate Increased metabolism of Progesterone caused by Cenobamate mediated induction of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [136]
Stiripentol DMMSDOY Moderate Decreased metabolism of Progesterone caused by Stiripentol mediated inhibition of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [148]
Fosphenytoin DMOX3LB Moderate Increased metabolism of Progesterone caused by Fosphenytoin mediated induction of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [136]
Rufinamide DMWE60C Moderate Increased metabolism of Progesterone caused by Rufinamide mediated induction of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [149]
Phenobarbital DMXZOCG Moderate Increased metabolism of Progesterone caused by Phenobarbital mediated induction of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [136]
Carbamazepine DMZOLBI Moderate Increased metabolism of Progesterone caused by Carbamazepine mediated induction of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [136]
Eslicarbazepine DMZREFQ Moderate Increased metabolism of Progesterone caused by Eslicarbazepine mediated induction of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [136]
Tazemetostat DMWP1BH Moderate Increased metabolism of Progesterone caused by Tazemetostat mediated induction of CYP450 enzyme. Follicular lymphoma [2A80] [150]
Itraconazole DMCR1MV Moderate Decreased metabolism of Progesterone caused by Itraconazole mediated inhibition of CYP450 enzyme. Fungal infection [1F29-1F2F] [140]
Miconazole DMPMYE8 Moderate Decreased metabolism of Progesterone caused by Miconazole mediated inhibition of CYP450 enzyme. Fungal infection [1F29-1F2F] [140]
Ketoconazole DMPZI3Q Moderate Decreased metabolism of Progesterone caused by Ketoconazole mediated inhibition of CYP450 enzyme. Fungal infection [1F29-1F2F] [140]
Ripretinib DM958QB Moderate Decreased clearance of Progesterone due to the transporter inhibition by Ripretinib. Gastrointestinal stromal tumour [2B5B] [142]
Sulfinpyrazone DMEV954 Moderate Increased metabolism of Progesterone caused by Sulfinpyrazone mediated induction of CYP450 enzyme. Gout [FA25] [136]
Boceprevir DMBSHMF Moderate Decreased metabolism of Progesterone caused by Boceprevir mediated inhibition of CYP450 enzyme. Hepatitis virus infection [1E50-1E51] [151]
Telaprevir DMMRV29 Moderate Decreased metabolism of Progesterone caused by Telaprevir mediated inhibition of CYP450 enzyme. Hepatitis virus infection [1E50-1E51] [152]
Rifampin DMA8J1G Moderate Increased metabolism of Progesterone caused by Rifampin mediated induction of CYP450 enzyme. HIV-infected patients with tuberculosis [1B10-1B14] [139]
Rifapentine DMCHV4I Moderate Increased metabolism of Progesterone caused by Rifapentine mediated induction of CYP450 enzyme. HIV-infected patients with tuberculosis [1B10-1B14] [136]
Brentuximab vedotin DMWLC57 Moderate Decreased clearance of Progesterone due to the transporter inhibition by Brentuximab vedotin. Hodgkin lymphoma [2B30] [153]
Delavirdine DM3NF5G Minor Decreased metabolism of Progesterone caused by Delavirdine mediated inhibition of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [154]
Efavirenz DMC0GSJ Moderate Increased metabolism of Progesterone caused by Efavirenz mediated induction of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [136]
Saquinavir DMG814N Moderate Decreased metabolism of Progesterone caused by Saquinavir mediated inhibition of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [155]
Darunavir DMN3GCH Moderate Decreased metabolism of Progesterone caused by Darunavir mediated inhibition of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [156]
Conivaptan DM1V329 Moderate Decreased metabolism of Progesterone caused by Conivaptan mediated inhibition of CYP450 enzyme. Hypo-osmolality/hyponatraemia [5C72] [157]
Berotralstat DMWA2DZ Moderate Decreased metabolism of Progesterone caused by Berotralstat mediated inhibition of CYP450 enzyme. Innate/adaptive immunodeficiency [4A00] [158]
Amobarbital DM0GQ8N Moderate Increased metabolism of Progesterone caused by Amobarbital mediated induction of CYP450 enzyme. Insomnia [7A00-7A0Z] [136]
Brigatinib DM7W94S Moderate Increased metabolism of Progesterone caused by Brigatinib mediated induction of CYP450 enzyme. Lung cancer [2C25] [159]
PF-06463922 DMKM7EW Moderate Increased metabolism of Progesterone caused by PF-06463922 mediated induction of CYP450 enzyme. Lung cancer [2C25] [136]
Selpercatinib DMZR15V Moderate Decreased metabolism of Progesterone caused by Selpercatinib mediated inhibition of CYP450 enzyme. Lung cancer [2C25] [149]
GDC-0199 DMH0QKA Major Decreased clearance of Progesterone due to the transporter inhibition by GDC-0199. Mature B-cell leukaemia [2A82] [142]
IPI-145 DMWA24P Moderate Decreased metabolism of Progesterone caused by IPI-145 mediated inhibition of CYP450 enzyme. Mature B-cell leukaemia [2A82] [160]
Arry-162 DM1P6FR Moderate Decreased clearance of Progesterone due to the transporter inhibition by Arry-162. Melanoma [2C30] [142]
Vemurafenib DM62UG5 Moderate Increased metabolism of Progesterone caused by Vemurafenib mediated induction of CYP450 enzyme. Melanoma [2C30] [136]
Dabrafenib DMX6OE3 Moderate Increased metabolism of Progesterone caused by Dabrafenib mediated induction of CYP450 enzyme. Melanoma [2C30] [136]
Exjade DMHPRWG Moderate Decreased metabolism of Progesterone caused by Exjade mediated inhibition of CYP450 enzyme. Mineral absorption/transport disorder [5C64] [161]
Rifabutin DM1YBHK Moderate Increased metabolism of Progesterone caused by Rifabutin mediated induction of CYP450 enzyme. Mycobacterium infection [1B10-1B21] [136]
Fedratinib DM4ZBK6 Moderate Decreased metabolism of Progesterone caused by Fedratinib mediated inhibition of CYP450 enzyme. Myeloproliferative neoplasm [2A20] [149]
Nilotinib DM7HXWT Moderate Decreased metabolism of Progesterone caused by Nilotinib mediated inhibition of CYP450 enzyme. Myeloproliferative neoplasm [2A20] [162]
Imatinib DM7RJXL Moderate Decreased metabolism of Progesterone caused by Imatinib mediated inhibition of CYP450 enzyme. Myeloproliferative neoplasm [2A20] [163]
Dasatinib DMJV2EK Moderate Decreased metabolism of Progesterone caused by Dasatinib mediated inhibition of CYP450 enzyme. Myeloproliferative neoplasm [2A20] [164]
Modafinil DMYILBE Minor Increased metabolism of Progesterone caused by Modafinil mediated induction of CYP450 enzyme. Narcolepsy [7A20] [165]
Rucaparib DM9PVX8 Moderate Decreased metabolism of Progesterone caused by Rucaparib mediated inhibition of CYP450 enzyme. Ovarian cancer [2C73] [166]
Abametapir DM2RX0I Moderate Decreased metabolism of Progesterone caused by Abametapir mediated inhibition of CYP450 enzyme. Pediculosis [1G00] [167]
Lefamulin DME6G97 Moderate Decreased metabolism of Progesterone caused by Lefamulin mediated inhibition of CYP450 enzyme. Pneumonia [CA40] [168]
Lonafarnib DMGM2Z6 Moderate Decreased metabolism of Progesterone caused by Lonafarnib mediated inhibition of CYP450 enzyme. Premature ageing appearance [LD2B] [169]
Enzalutamide DMGL19D Moderate Increased metabolism of Progesterone caused by Enzalutamide mediated induction of CYP450 enzyme. Prostate cancer [2C82] [136]
Bosentan DMIOGBU Moderate Increased metabolism of Progesterone caused by Bosentan mediated induction of CYP450 enzyme. Pulmonary hypertension [BB01] [136]
Riociguat DMXBLMP Moderate Decreased clearance of Progesterone due to the transporter inhibition by Riociguat. Pulmonary hypertension [BB01] [142]
Temsirolimus DMS104F Moderate Increased plasma concentrations of Progesterone and Temsirolimus due to competitive inhibition of the same metabolic pathway. Renal cell carcinoma [2C90] [170]
Nafcillin DMN9RPO Moderate Increased metabolism of Progesterone caused by Nafcillin mediated induction of CYP450 enzyme. Rheumatoid arthritis [FA20] [136]
Telotristat ethyl DMDIYFZ Moderate Increased metabolism of Progesterone caused by Telotristat ethyl mediated induction of CYP450 enzyme. Small intestine developmental anomaly [DA90] [149]
Larotrectinib DM26CQR Moderate Decreased metabolism of Progesterone caused by Larotrectinib mediated inhibition of CYP450 enzyme. Solid tumour/cancer [2A00-2F9Z] [142]
Armodafinil DMGB035 Minor Increased metabolism of Progesterone caused by Armodafinil mediated induction of CYP450 enzyme. Solid tumour/cancer [2A00-2F9Z] [165]
Fostamatinib DM6AUHV Moderate Decreased clearance of Progesterone due to the transporter inhibition by Fostamatinib. Thrombocytopenia [3B64] [171]
Lusutrombopag DMH6IKO Moderate Decreased clearance of Progesterone due to the transporter inhibition by Lusutrombopag. Thrombocytopenia [3B64] [166]
Apixaban DM89JLN Moderate Decreased clearance of Progesterone due to the transporter inhibition by Apixaban. Thrombosis [DB61-GB90] [149]
Sirolimus DMGW1ID Moderate Increased plasma concentrations of Progesterone and Sirolimus due to competitive inhibition of the same metabolic pathway. Transplant rejection [NE84] [170]
Tacrolimus DMZ7XNQ Moderate Increased plasma concentrations of Progesterone and Tacrolimus due to competitive inhibition of the same metabolic pathway. Transplant rejection [NE84] [170]
Elagolix DMB2C0E Moderate Increased metabolism of Progesterone caused by Elagolix mediated induction of CYP450 enzyme. Uterine fibroid [2E86] [136]
⏷ Show the Full List of 85 DDI Information of This Drug

Drug Inactive Ingredient(s) (DIG) and Formulation(s) of This Drug

DIG
DIG Name DIG ID PubChem CID Functional Classification
Allura red AC dye E00338 33258 Colorant
Quinoline yellow WS E00309 24671 Colorant
Sunset yellow FCF E00255 17730 Colorant
Ammonia E00007 222 Alkalizing agent
Eisenoxyd E00585 56841934 Colorant
Ferric hydroxide oxide yellow E00539 23320441 Colorant
Ferrosoferric oxide E00231 14789 Colorant
Glycerin E00026 753 Antimicrobial preservative; Emollient; Flavoring agent; Humectant; Lubricant; Plasticizing agent; Solvent; Suppository base; Tonicity agent; Viscosity-controlling agent
Polyethylene glycol 400 E00653 Not Available Coating agent; Diluent; Ointment base; Plasticizing agent; Solvent; Suppository base; lubricant
Propylene glycol E00040 1030 Antimicrobial preservative; Humectant; Plasticizing agent; Solvent
Soybean lecithin E00637 Not Available Other agent
Titanium dioxide E00322 26042 Coating agent; Colorant; Opacifying agent
Water E00035 962 Solvent
⏷ Show the Full List of 13 Pharmaceutical Excipients of This Drug
Pharmaceutical Formulation
Formulation Name Drug Dosage Dosage Form Route
Progesterone 100 mg capsule 100 mg Oral Capsule Oral
Progesterone 200 mg capsule 200 mg Oral Capsule Oral
Jump to Detail Pharmaceutical Formulation Page of This Drug

References

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169 Product Information. Zokinvy (lonafarnib). Eiger BioPharmaceuticals, Palo Alto, CA.
170 Product Information. Prograf (tacrolimus). Fujisawa, Deerfield, IL.
171 Product Information. Tavalisse (fostamatinib). Rigel Pharmaceuticals, South San Francisco, CA.