Details of the Drug-Related molecule(s) Interaction Atlas

Phenolsulfonphthalein Drug Info

3,3-Bis(4-hydroxyphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide; 4,4'-(3H-2,1-Benzoxathiol-3-ylidene)diphenol S,S-dioxide; BRN 0326470; EINECS 205-609-7; Fenolipuna; I6G9Y0J1OJ; MFCD00003552; NSC 10459; NSC10459; PHENOL RED; PSP; PSP (indicator); Phenol Red, ACS reagent; Phenol red; Phenol, 4,4'-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis-; Phenolred; Phenolsulfonephthalein; Phenolsulphonphthalein; Phenosulfophthalein; Sulfonphthal; Sulphental; Sulphonthal; UNII-I6G9Y0J1OJ; phenolsulfonphthalein

Cross-matching ID

PubChem CID

4766

ChEBI ID

CHEBI:31991

CAS Number

CAS 143-74-8

TTD Drug ID

DMCTUAD

VARIDT Drug ID

DR01234

General Information of Drug (ID: DMCTUAD)

Molecule-Related Drug Atlas

Molecule Type:

DTP

DOT

Drug Status:

Approved Drug(s)

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Drug(s) Transported By Organic anion transporter 3 (SLC22A8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[6]
Dinoprostone	DMTYOPD	Medical abortion	JA00.1Z	Approved	[7]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[8]
Prasterone	DM67VKL	Chronic obstructive pulmonary disease	CA22	Approved	[9]
Pravastatin	DM6A0X7	Adult acute monocytic leukemia		Approved	[10]
L-Tryptophan	DMIBH7M	Depression	6A70-6A7Z	Approved	[11]
Mercaptopurine	DMTM2IK	Acute lymphoblastic leukaemia	2A85	Approved	[12]
PITAVASTATIN CALCIUM	DM1UJO0	Dyslipidemia	5C80-5C81	Approved	[13]
Rosuvastatin	DMMIQ7G	Arteriosclerosis	BD40	Approved	[14]
Cilostazol	DMZMSCT	Intermittent claudication	BD40.00	Approved	[15]
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Drug(s) Affected By Progesterone receptor (PGR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[16]
Drospirenone	DM1A9W3	Acne vulgaris	ED80	Approved	[17]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[18]
Estrone	DM5T6US	Acne vulgaris	ED80	Approved	[19]
Tibolone	DM78XFG	Anabolic metabolism	5C50-5C8Z	Approved	[20]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[21]
Exemestane	DM9HPW3	Hormonally-responsive breast cancer	2C60-2C65	Approved	[22]
Goserelin	DMAT8CG	Breast cancer	2C60-2C65	Approved	[23]
Lindane	DMB8CNL	Infestations of lice and scabies	1G00.Z	Approved	[24]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[25]
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Drug(s) Affected By POU domain, class 5, transcription factor 1 (POU5F1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[26]
Ciprofloxacin XR	DM2NLS9	Acute gonococcal cervicitis		Approved	[27]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[28]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[29]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[30]
Chlorpromazine	DMBGZI3	Acute intermittent hepatic porphyria	5C58.11	Approved	[31]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[32]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[33]
Lamotrigine	DM8SXYG	Bipolar disorder	6A60	Approved	[34]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[35]
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Drug(s) Affected By Myeloperoxidase (MPO)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dapsone	DM4LT8A	Acne vulgaris	ED80	Approved	[36]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[37]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[36]
Sulfamethoxazole	DMB08GE	Acute otitis media	AB00	Approved	[36]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[38]
Salicyclic acid	DM2F8XZ	Acne vulgaris	ED80	Approved	[39]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[40]
Penicillamine	DM40EF6	Cystinuria	5C60.2	Approved	[41]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[42]
Propylthiouracil	DM6D7N8	Hyperthyroidism	5A02	Approved	[43]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Organic anion transporter 3 (SLC22A8)	DTVP67E	S22A8_HUMAN	Substrate	[1]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Myeloperoxidase (MPO)	OTOOXLIN	PERM_HUMAN	Biotransformations	[2]
POU domain, class 5, transcription factor 1 (POU5F1)	OTDHHN7O	PO5F1_HUMAN	Gene/Protein Processing	[3]
Progesterone receptor (PGR)	OT0FZ3QE	PRGR_HUMAN	Gene/Protein Processing	[4]
UDP-glucuronosyltransferase 2B15	OTABTFU2	UDB15_HUMAN	Biotransformations	[5]

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