Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMKYQO4)

Drug Name
dehydroascorbic acid Drug Info
Synonyms dehydroascorbate
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
440667
ChEBI ID
CHEBI:27956
CAS Number
CAS 490-83-5
TTD Drug ID
DMKYQO4
VARIDT Drug ID
DR00260
INTEDE Drug ID
DR2035

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Transported By Glucose transporter type 1, erythrocyte/brain (SLC2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [9]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
D-glucose DMMG2TO Discovery agent N.A. Investigative [11]
Arsenite DMBCO4Q Discovery agent N.A. Investigative [12]
Drug(s) Transported By Glucose transporter type 14 (SLC2A14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [2]
Drug(s) Metabolized By Glutathione S-transferase omega-1 (GSTO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [4]
Drug(s) Metabolized By Glutathione S-transferase omega-2 (GSTO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [4]
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [13]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [14]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [15]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [16]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [17]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [18]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [17]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [19]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [20]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [21]
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Drug(s) Affected By Catalase (CAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [22]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [23]
Haloperidol DM96SE0 Delirium Approved [24]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [25]
Selenium DM25CGV N. A. N. A. Approved [26]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [27]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [28]
Methotrexate DM2TEOL Anterior urethra cancer Approved [29]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [30]
Quercetin DM3NC4M Obesity 5B81 Approved [31]
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Drug(s) Affected By Superoxide dismutase , mitochondrial (SOD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [32]
Selenium DM25CGV N. A. N. A. Approved [33]
Methotrexate DM2TEOL Anterior urethra cancer Approved [34]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [35]
Epinephrine DM3KJBC Acute asthma CA23 Approved [36]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [38]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [39]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [40]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [42]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [43]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [44]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [45]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [24]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [46]
Verapamil DMA7PEW Angina pectoris BA40 Approved [47]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [48]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [49]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [50]
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Drug(s) Affected By Cytochrome c (CYCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [51]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [52]
Gefitinib DM15F0X Colon adenocarcinoma Approved [53]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [54]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [55]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [56]
Methotrexate DM2TEOL Anterior urethra cancer Approved [29]
Quercetin DM3NC4M Obesity 5B81 Approved [31]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [57]
Pefloxacin DM49IGF Gonococcal urethritis 1A70.0Y Approved [58]
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Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [59]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [60]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [61]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [62]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [61]
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [61]
Quercetin DM3NC4M Obesity 5B81 Approved [31]
Fluoxetine DM3PD2C Bipolar depression Approved [61]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
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Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [59]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [18]
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
Quercetin DM3NC4M Obesity 5B81 Approved [31]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Glucose transporter type 14 (SLC2A14) DT18YD9 GTR14_HUMAN Substrate [2]
Glucose transporter type 1, erythrocyte/brain (SLC2A1) DTG3T6X GTR1_HUMAN Substrate [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Glutathione S-transferase omega-2 (GSTO2) DEHMPZR GSTO2_HUMAN Substrate [4]
Glutathione S-transferase omega-1 (GSTO1) DEZSNJD GSTO1_HUMAN Substrate [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [5]
Catalase (CAT) OTHEBX9R CATA_HUMAN Gene/Protein Processing [5]
Cytochrome c (CYCS) OTBFALJD CYC_HUMAN Protein Interaction/Cellular Processes [5]
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) OTA675TJ GTR1_HUMAN Regulation of Drug Effects [6]
Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2) OTBL2W7R GTR2_HUMAN Regulation of Drug Effects [7]
Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) OT2HZK5M GTR3_HUMAN Regulation of Drug Effects [8]
Superoxide dismutase , mitochondrial (SOD2) OTIWXGZ9 SODM_HUMAN Gene/Protein Processing [5]

References

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