Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DE4OGUF)

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

10 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[1]
Amodiaquine	DME4RA8	Malaria	1F40-1F45	Approved	[1]
Buspirone	DMBS632	Anxiety disorder	6B00-6B0Z	Approved	[1], [2]
Chlorzoxazone	DMCYVDT	Acute pain	MG31	Approved	[3], [1]
Dextromethorphan	DMUDJZM	Allergic rhinitis	CA08.0	Approved	[1]
Diclofenac	DMPIHLS	Chronic renal failure	GB61.Z	Approved	[4]
Meclofenamic acid	DM05FXR	Ankylosing spondylitis	FA92.0	Approved	[4]
Mefenamic acid	DMK7HFI	Dysmenorrhea	GA34.3	Approved	[4]
Nifedipine	DMSVOZT	Angina pectoris	BA40	Approved	[3], [1]
Propranolol	DM79NTF	Angina pectoris	BA40	Approved	[2]
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⏷ Show the Full List of 10 Approved Drug(s)

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GEA-6414	DM8J0MK	N. A.	N. A.	Phase 1/2	[4]
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4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aniline	DMLCAR9	N. A.	N. A.	Investigative	[3], [1]
Benzyloxyresorufin	DM26SR7	N. A.	N. A.	Investigative	[1]
METHYLENEDIOXYMETHAMPHETAMINE	DMYVU47	Discovery agent	N.A.	Investigative	[1]
Mononitrophenol	DM4QO9G	N. A.	N. A.	Investigative	[3], [1]
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Molecule Interaction Atlas

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References

1	The bacterial P450 BM3: a prototype for a biocatalyst with human P450 activities. Trends Biotechnol. 2007 Jul;25(7):289-98.
2	acillus megaterium SF185 spores exert protective effects against oxidative stress in vivo and in vitro. Sci Rep. 2019 Aug 19;9(1):12082.
3	Wild-type CYP102A1 as a biocatalyst: turnover of drugs usually metabolised by human liver enzymes. J Biol Inorg Chem. 2007 Mar;12(3):313-23.
4	Both reactivity and accessibility are important in cytochrome P450 metabolism: a combined DFT and MD study of fenamic acids in BM3 mutants. J Chem Inf Model. 2019 Feb 25;59(2):743-753.