General Information of Drug (ID: DM7HXWT)

Drug Name
Nilotinib Drug Info
Synonyms
NIL; Nilotinibum; Tasigna (Novartis); Nilotinib (INN/USAN); Nilotinib, AMN107, Tasigna; Tasigna, AMN-107, Nilotinib; L-1-yl)-3-(trifluoromethyl)phenyl]benzamide; Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-(9CI); 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazo; 4-Methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide; 4-Methyl-N-[3-(4-methylimidazol-1-yl)-5-trifluoromethylphenyl]-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzamide; 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide; Nilotinib (BCR-ABL inhibitor 2nd gen)
Indication
Disease Entry ICD 11 Status REF
Chronic myelogenous leukaemia 2A20.0 Approved [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
644241
ChEBI ID
CHEMBL255863
CAS Number
CAS 641571-10-0
TTD Drug ID
DM7HXWT
VARIDT Drug ID
DR00013
INTEDE Drug ID
DR1155
ACDINA Drug ID
D00468

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [13]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [13]
Asciminib DM7EVUF Chronic myeloid leukaemia 2A20 Approved [14]
Radotinib DMWA74Y leukaemia 2A60-2B33 Phase 3 [15]
ABL 001 DMMF5K4 Chronic myeloid leukaemia 2A20 Phase 3 [16]
ICLUSIG DM1SQSE Acute lymphoblastic leukaemia 2A85 Phase 3 [17]
Bafetinib DM7586F Bone disease FC0Z Phase 2 [18]
AN-019 DMJ7QP8 Chronic myelogenous leukaemia 2A20.0 Phase 2 [19]
HQP1351 DMQ30X2 Chronic myeloid leukaemia 2A20 Phase 2 [20]
NPB-001-056 DM78KMT Chronic myelogenous leukaemia 2A20.0 Phase 1/2 [21]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [22]
Methotrexate DM2TEOL Anterior urethra cancer Approved [23]
Folic Acid DMEMBJC Colorectal carcinoma Approved [24]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [25]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [26]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [27]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [28]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [29]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [30]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [31]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [32]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [33]
Methotrexate DM2TEOL Anterior urethra cancer Approved [34]
Folic Acid DMEMBJC Colorectal carcinoma Approved [35]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [34]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [34]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [36]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [34]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [37]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [38]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [39]
Methotrexate DM2TEOL Anterior urethra cancer Approved [40]
Folic Acid DMEMBJC Colorectal carcinoma Approved [41]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [42]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [43]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [44]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [45]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [44]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [46]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [47]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [49]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [4]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [50]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [4]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [51]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [52]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [53]
Cerivastatin DMXCM7H Hyperlipidaemia 5C80 Approved [54]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [51]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [4]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [56]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [57]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [4]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [58]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [52]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [54]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [59]
Cerivastatin DMXCM7H Hyperlipidaemia 5C80 Approved [54]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [60]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [61]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [62]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [63]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [64]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [65]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [66]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [67]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [61]
Verapamil DMA7PEW Angina pectoris BA40 Approved [68]
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Drug(s) Metabolized By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [69]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [7]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [7]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [70]
Verapamil DMA7PEW Angina pectoris BA40 Approved [71]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [72]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [73]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [7]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [74]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [75]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [76]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [76]
Gefitinib DM15F0X Colon adenocarcinoma Approved [77]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [78]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [79]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [80]
Methotrexate DM2TEOL Anterior urethra cancer Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [82]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [83]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [84]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [85]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [86]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [87]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [88]
Cepharanthine DM9Y5JB N. A. N. A. Approved [89]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [90]
Clozapine DMFC71L Schizophrenia 6A20 Approved [91]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [92]
Trifluoperazine DMKBYWI Anxiety Approved [93]
Olanzapine DMPFN6Y Bipolar depression Approved [91]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [94]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [95]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [96]
Quercetin DM3NC4M Obesity 5B81 Approved [97]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [98]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [99]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [8]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [100]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [101]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [102]
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Drug(s) Affected By Protein c-Fos (FOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [103]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [104]
Verapamil DMA7PEW Angina pectoris BA40 Approved [105]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [106]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [105]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [107]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [108]
Methotrexate DM2TEOL Anterior urethra cancer Approved [109]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [110]
Quercetin DM3NC4M Obesity 5B81 Approved [111]
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Drug(s) Affected By Transcription factor Jun (JUN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [112]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [113]
Fructose DM43AN2 Vomiting MD90 Approved [78]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [114]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [115]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [106]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [116]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [117]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [118]
Methotrexate DM2TEOL Anterior urethra cancer Approved [119]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [120]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [12]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [12]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [12]
Testosterone enanthate DMB6871 N. A. N. A. Approved [121]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [122]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [123]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [12]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [12]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [124]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [125]
Gefitinib DM15F0X Colon adenocarcinoma Approved [126]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [127]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [128]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [129]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [130]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [129]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [131]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [132]
Methotrexate DM2TEOL Anterior urethra cancer Approved [133]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [115]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [134]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [135]
Quercetin DM3NC4M Obesity 5B81 Approved [136]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [98]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [137]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [103]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [138]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [139]
Leflunomide DMR8ONJ Arthritis FA20 Approved [140]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [135]
Methotrexate DM2TEOL Anterior urethra cancer Approved [141]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [137]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [142]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [12]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [144]
Dabigatran DMDI6R4 Stroke 8B20 Approved [12]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [12]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [12]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [96]
Quercetin DM3NC4M Obesity 5B81 Approved [145]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [96]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [120]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [146]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [147]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [148]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [96]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [150]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [151]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [12]
Panobinostat DM58WKG Chronic graft versus host disease Approved [152]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [12]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [153]
Dabigatran DMDI6R4 Stroke 8B20 Approved [12]
Folic Acid DMEMBJC Colorectal carcinoma Approved [154]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [12]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [155]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [156]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [120]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [12]
Panobinostat DM58WKG Chronic graft versus host disease Approved [152]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [12]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [157]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [12]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Dabigatran DMDI6R4 Stroke 8B20 Approved [12]
Folic Acid DMEMBJC Colorectal carcinoma Approved [155]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [159]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [160]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [106]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [161]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [96]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [162]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [163]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [164]
Methotrexate DM2TEOL Anterior urethra cancer Approved [165]
Quercetin DM3NC4M Obesity 5B81 Approved [136]
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Drug(s) Affected By Crk-like protein (CRKL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [166]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [167]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [168]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [169]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [170]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [171]
Rigosertib DMOSTXF Myelodysplastic syndrome 2A37 Phase 3 [172]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [173]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [174]
PMID25656651-Compound-5 DMAI95U Chronic myeloid leukaemia 2A20 Patented [175]
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Drug(s) Affected By Homeobox protein MOX-1 (MEOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [12]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [12]
Panobinostat DM58WKG Chronic graft versus host disease Approved [152]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [177]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [12]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [138]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [12]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [144]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [12]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [12]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [12]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [12]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [12]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [12]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [178]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [12]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [12]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [12]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [12]
Dabigatran DMDI6R4 Stroke 8B20 Approved [12]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [12]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [12]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [12]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [178]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [12]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [12]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [12]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [12]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [155]
Dabigatran DMDI6R4 Stroke 8B20 Approved [12]
Ethanol DMDRQZU Chronic pain MG30 Approved [179]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [12]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [137]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [122]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [180]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [181]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [182]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [183]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [178]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [184]
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Drug(s) Affected By Eyes absent homolog 1 (EYA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [185]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [99]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [12]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [12]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [12]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [12]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [12]
Dabigatran DMDI6R4 Stroke 8B20 Approved [12]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [12]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [12]
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Drug(s) Affected By Neurogenin-2 (NEUROG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [99]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [12]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [12]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [12]
Leflunomide DMR8ONJ Arthritis FA20 Approved [140]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [144]
Dabigatran DMDI6R4 Stroke 8B20 Approved [12]
Folic Acid DMEMBJC Colorectal carcinoma Approved [155]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [12]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [12]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fusion protein Bcr-Abl (Bcr-Abl) TTS7G69 BCR_HUMAN-ABL1_HUMAN Modulator [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [3]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [3]
Organic anion transporting polypeptide 1B1 (SLCO1B1) DT3D8F0 SO1B1_HUMAN Substrate [4]
Organic anion transporting polypeptide 1B3 (SLCO1B3) DT9C1TS SO1B3_HUMAN Substrate [4]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [5]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [6]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Acetyl-CoA carboxylase 1 (ACACA) OT5CQPZY ACACA_HUMAN Post-Translational Modifications [8]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Drug Response [9]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Drug Response [10]
Crk-like protein (CRKL) OTOYSD1R CRKL_HUMAN Post-Translational Modifications [11]
Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6) OTAFHAVI ATF6A_HUMAN Gene/Protein Processing [11]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Gene/Protein Processing [11]
ER degradation-enhancing alpha-mannosidase-like protein 1 (EDEM1) OTWHN69S EDEM1_HUMAN Gene/Protein Processing [11]
Eyes absent homolog 1 (EYA1) OTHU807A EYA1_HUMAN Gene/Protein Processing [12]
Homeobox protein Hox-B7 (HOXB7) OTC7WYU8 HXB7_HUMAN Gene/Protein Processing [12]
Homeobox protein Hox-B9 (HOXB9) OTMVHQOU HXB9_HUMAN Gene/Protein Processing [12]

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