Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMFH15Z)

Drug Name
Bendamustine hydrochloride Drug Info
Synonyms Treanda (TN)
Indication
Disease Entry ICD 11 Status REF
leukaemia 2A60-2B33 Approved [1]
Cross-matching ID
PubChem CID
77082
CAS Number
CAS 3543-75-7
TTD Drug ID
DMFH15Z
INTEDE Drug ID
DR0188
ACDINA Drug ID
D00869

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Human Deoxyribonucleic acid (hDNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [7]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [8]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [9]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [10]
Carboplatin DMG281S Adenocarcinoma 2D40 Approved [11]
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [12]
Procarbazine DMIK367 Hodgkin lymphoma 2B30 Approved [13]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [14]
Dacarbazine DMNPZL4 Adenocarcinoma 2D40 Approved [15]
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Drug(s) Metabolized By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [16]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [17]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [18]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [19]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [20]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [21]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [22]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [23]
Verapamil DMA7PEW Angina pectoris BA40 Approved [24]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [25]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [26]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [28]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [29]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [30]
Paclitaxel DMLB81S Breast carcinoma Approved [31]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [32]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [33]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [34]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [35]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [36]
Gefitinib DM15F0X Colon adenocarcinoma Approved [37]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [38]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [39]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [40]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [41]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [40]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [42]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [43]
Methotrexate DM2TEOL Anterior urethra cancer Approved [44]
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Drug(s) Affected By Beta-galactosidase (GLB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [45]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [47]
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [50]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [51]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [52]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [53]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [54]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [55]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [56]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [57]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [30]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [58]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [59]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [60]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [61]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [62]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [63]
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Drug(s) Affected By Caspase-7 (CASP7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [64]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [65]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [67]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [68]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [68]
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [69]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [70]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [71]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [72]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [73]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [36]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [74]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [75]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [76]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [39]
Meloxicam DM2AR7L Arthritis FA20 Approved [77]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [78]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [79]
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Drug(s) Affected By Caspase-6 (CASP6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [80]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [81]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Methotrexate DM2TEOL Anterior urethra cancer Approved [83]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [84]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [85]
Quercetin DM3NC4M Obesity 5B81 Approved [86]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [87]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [88]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 3 (BIRC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [89]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [63]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [90]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [39]
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [91]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [92]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [93]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [94]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 2 (BIRC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [89]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [63]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [95]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [96]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [97]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [98]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [99]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [94]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [100]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [101]
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Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [102]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [103]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [104]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [81]
Gefitinib DM15F0X Colon adenocarcinoma Approved [105]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [106]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [39]
Selenium DM25CGV N. A. N. A. Approved [107]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [78]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
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Drug(s) Affected By PRKC apoptosis WT1 regulator protein (PAWR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [108]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [109]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [110]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [111]
Leflunomide DMR8ONJ Arthritis FA20 Approved [112]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [113]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [114]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [115]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [53]
Menthol DMG2KW7 Back pain ME84.Z Approved [116]
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Drug(s) Affected By Diablo IAP-binding mitochondrial protein (DIABLO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [117]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [118]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [39]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [119]
Quercetin DM3NC4M Obesity 5B81 Approved [120]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [122]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [124]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [53]
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Drug(s) Affected By Death domain-associated protein 6 (DAXX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [90]
Quercetin DM3NC4M Obesity 5B81 Approved [125]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [126]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [127]
Leflunomide DMR8ONJ Arthritis FA20 Approved [112]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [128]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [114]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [53]
Menthol DMG2KW7 Back pain ME84.Z Approved [116]
Arsenic DMTL2Y1 N. A. N. A. Approved [129]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Human Deoxyribonucleic acid (hDNA) TTUTN1I NOUNIPROTAC Modulator [1]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 1A2 (CYP1A2) Main DME DEJGDUW CP1A2_HUMAN Substrate [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Gene/Protein Processing [3]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Gene/Protein Processing [4]
Beta-galactosidase (GLB1) OTB0TKAG BGAL_HUMAN Gene/Protein Processing [5]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [4]
Caspase-6 (CASP6) OTXLD3EC CASP6_HUMAN Gene/Protein Processing [4]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Gene/Protein Processing [4]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [4]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [4]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [4]
Death domain-associated protein 6 (DAXX) OTX6O7PL DAXX_HUMAN Gene/Protein Processing [4]

References

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